caffeine and quinine

caffeine has been researched along with quinine in 134 studies

Research

Studies (134)

TimeframeStudies, this research(%)All Research%
pre-199070 (52.24)18.7374
1990's12 (8.96)18.2507
2000's19 (14.18)29.6817
2010's28 (20.90)24.3611
2020's5 (3.73)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Choo, YM; Doerksen, RJ; Gertsch, J; Hamann, MT; Jacob, MR; Khan, SI; Kudrimoti, S; Madgula, V; Mayer, AM; Odde, S; Peng, J; Pennaka, HK; Prasanna, S; Rao, KV; Tekwani, BL; Tu, LC; Wang, B1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN1
Akaike, N; Sato, M1
Bowman, WC; Khan, HH; Savage, AO1
Connett, RJ1
Burrin, DH; Syson, AJ; Theobald, TC2
Cagan, RH1
Moffat, AC1
Peck, JW1
Price, NR; Williams, AJ1
Kusionowicz, S1
Holecková, H; Stichová, E; Zahradnicek, M1
Inoue, T; Inoue, Y; Ishii, T; Tatsuzawa, M1
Piasecka, H1
Alonso, GL; Arrigo, DM; Bazerque, PM; Terradas, SE1
Brown, K; Newland, MC1
Culberson, JC; Kellogg, MS; Muller, GW; Roy, G; Schiffman, SS; Walters, DE; Warwick, ZS; Ziegler, J1
Røed, A1
Baró, I; Escande, D1
Krnjevic, K; Leblond, J1
Savage, AO1
Chicz-DeMet, A; DeMet, E; Nelson, J; Sangdahl, C; Stein, MK; Tran, C1
Kashiwayanagi, M; Kumazawa, T; Kurihara, K1
Cox, WM; Heppner, CC; Kemble, ED1
Rentsch, G; Staubesand, J; Wittekind, D1
Carvalho, AP; Madeira, VM1
Kurihara, K1
Beyrich, T; Schleuder, M1
Falk, M; Fürst, W1
Doctor, RB; Jindal, MN; Kelkar, VV1
Behnsen, G; Kühn, L; Pfeifer, S1
Koyama, N; Kurihara, K1
Greenhow, EJ; Spencer, LE1
Shine, KI1
Paumgartten, FJ; Suarez-Kurtz, G1
Chasar, DW; Toth, GB1
Kawahara, Y; Yamada, S1
Samková, M1
Huddart, H2
Wilkoszewski, R1
Paschke, M; Schwanitz, F1
Ahmed, I; Olowe, O1
Hinkes, MJ; Isaacson, A; Taylor, SR1
Isaacson, A; Sandow, A; Yamaji, K1
Van der Kloot, WG1
Harbin, JE; Robbins, RC1
Robbins, RC1
Clinch, NF1
Fecko, J; Przybylek-Piontek, W1
Carvalho, AP1
Guillory, JK; Hwang, SC; Lach, JL1
Beyrich, T1
Isaacson, A; Sandow, A1
Sato, T; Sugimoto, K1
Hartung, K; Hermann, A1
Kasai, M; Yamamoto, N1
Braga da Costa, MJ; Coutinho, S; Suarez-Kurtz, G1
Grossi, G; Lombardo, E; Mondi', C; Santoni, G1
Suarez-Kurtz, G1
De Ritis, G; De Rossi, P; Diamanti, E; Lauretti, MC; Maggio, F; Marchionni, G; Morabito, F; Roscioni, C1
El-Fadaly, MA; El-Gendi, AY; Hassan, AB; Mohamed, MF1
Coleman, AW; Coleman, JR1
Katsuragi, Y; Kurihara, K; Lee, C; Otsuji, K; Sugiura, Y1
Chen, S; Inoue, R; Ito, Y1
Finger, TE; Lamb, CF1
Kashiwayanagi, M; Katsuragi, Y; Kumazawa, T; Kurihara, K; Matsuoka, I; Shoji, T1
Apfeldorf, WJ; Shear, MK1
Beauchamp, GK; Breslin, PA1
Nelson, SL; Sanregret, JD1
Caprio, J; Marui, T; Ogawa, K1
Falk, JL; Lau, CE; Schwartz, A; Yosef, E1
Frank, O; Hofmann, T; Ottinger, H1
Cubero-Castillo, E; Noble, AC1
SEYFERT, B1
ETZENSPERGER, J1
BEDFORD, C; CHILD, KJ; TOMICH, EG1
NIYOGI, SK; STREET, HV1
GRAHAM, HD; THOMAS, LB1
MALONE, MH; RAGOZZINO, PW1
DODION-FRANSEN, J1
CARLASSARE, M1
KAMP, W1
Bouverat, BP; Frank, ME; Hettinger, TP; MacKinnon, BI1
Blizard, DA; Frank, ME; Hettinger, TP; Katsuie, Y; Makino, J; Mizutani, M; Umezawa, H; Wada, Y1
Hiroi, M; Marion-Poll, F; Meunier, N; Tanimura, T1
Breslin, PA; Hansen, JL; Martin, NG; Reed, DR; Wright, MJ1
Cole, L; Heard, C1
Keast, RS; Roper, J1
Maehashi, K; Matano, M; Nonaka, M; Udaka, S; Yamamoto, Y1
Bertram, HJ; Blings, M; Hoffmann-Lücke, P; Krammer, GE; Ley, JP; Paetz, S1
Andersson, TB; Bäckström, T; Bertilsson, L; Böttiger, Y; Bredberg, E; Diczfalusy, U; Kanebratt, KP; Sparve, E1
Hernandez Salazar, LT; Laska, M; Rivas Bautista, RM1
Jiao, Y; Lee, Y; Montell, C; Moon, SJ1
Masek, P; Scott, K1
Marion-Poll, F; Reeb, P; Sellier, MJ1
Guerin, PM; Kessler, S; Vlimant, M1
Breitkreutz, J; Eckert, C; Pein, M; Preis, M1
Sanderson, MJ; Tan, X1
Nasri, S; Nili-Ahmadabadi, A; Ostad, SN; Sabzevari, O; Tavakoli, F; Tayeboon, GS1
Mansfield, CJ; Mathew, PS; Mennella, JA; Reed, DR; Roberts, KM2
Dinnella, C; Masi, C; Monteleone, E; Prescott, J1
Frías Tejera, I; González Reyes, AB; Gutiérrez Fernández, AJ; Hardisson de la Torre, A; Revert Gironés, C; Rubio Armendáriz, C1
Boisseau, RP; Dussutour, A; Vogel, D1
Asparch, Y; Barrozo, RB; Masagué, S; Minoli, S; Pontes, G1
Coupland, J; Elias, R; Euston, S; Hayes, J; Tenney, K1
Behrens, M; Cheled-Shoval, S; Di Pizio, A; Korb, A; Meyerhof, W; Niv, MY; Uni, Z1
Coppola, DM; Slotnick, B1
Browne, T; Conti, T; Fiorentin, TR; Krotulski, AJ; Logan, BK; Martin, DM; Triplett, J1
Breslin, PAS; Couvy-Duchesne, B; de Zubicaray, GI; Hwang, LD; Martin, NG; McMahon, K; Reed, DR; Strike, LT; Wright, MJ1
Besser, G; Liu, DT; Mueller, CA; Oeller, F; Renner, B1
George, O; Kimbrough, A; Lee, CH1
Barrozo, RB; Muñoz, IJ; Schilman, PE1
Bakke, AJ; Coupland, JN; Elias, RJ; Hayes, JE; Tenney, K1
Balaji, A; Breaker, RR; Midy, MK; Mohsen, MG1

Reviews

4 review(s) available for caffeine and quinine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Filling of drugs into gelatine capsules in pharmacies].
    Ceskoslovenska farmacie, 1969, Volume: 18, Issue:6

    Topics: Acetanilides; Antipyrine; Aspirin; Bicarbonates; Bismuth; Caffeine; Capsules; Codeine; Dosage Forms; Methods; Nitrates; Pharmacies; Phosphates; Quinine; Salicylates; Sodium; Starch; Sulfates; Technology, Pharmaceutical

1969
Ca2+ activated K+ conductance in molluscan neurones.
    Cell calcium, 1983, Volume: 4, Issue:5-6

    Topics: Action Potentials; Animals; Apamin; Aplysia; Binding Sites; Caffeine; Calcium; Electric Conductivity; Gallamine Triethiodide; Helix, Snails; Ion Channels; Membrane Potentials; Mollusca; Neurons; Photoreceptor Cells; Potassium; Quinidine; Quinine; Ruthenium Red; Tetraethylammonium Compounds

1983
Receptor mechanisms of bitter substances.
    Physiology & behavior, 1994, Volume: 56, Issue:6

    Topics: Amino Acid Sequence; Animals; Caffeine; GTP-Binding Proteins; Humans; Molecular Sequence Data; Quinine; Receptors, Cell Surface; RNA, Messenger; Strychnine; Synaptic Transmission; Taste; Taste Buds; Theophylline

1994

Trials

4 trial(s) available for caffeine and quinine

ArticleYear
[Comparison of the clinical activity of 2 analgesic formulations].
    La Clinica terapeutica, 1981, Mar-31, Volume: 96, Issue:6

    Topics: Adult; Analgesics; Antipyrine; Caffeine; Clinical Trials as Topic; Drug Combinations; Female; Humans; Lactose; Pain; Phenacetin; Quinine

1981
Effect of compound sequence on bitterness enhancement.
    Chemical senses, 2001, Volume: 26, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Caffeine; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Female; Humans; Male; Middle Aged; Quaternary Ammonium Compounds; Quinine; Sensation; Sensitivity and Specificity; Taste

2001
Cytochrome P450 induction by rifampicin in healthy subjects: determination using the Karolinska cocktail and the endogenous CYP3A4 marker 4beta-hydroxycholesterol.
    Clinical pharmacology and therapeutics, 2008, Volume: 84, Issue:5

    Topics: Adult; Anti-Ulcer Agents; Antibiotics, Antitubercular; Antihypertensive Agents; Antimalarials; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 Enzyme System; Drug Combinations; Enzyme Induction; Female; Humans; Hydroxycholesterols; Losartan; Male; Middle Aged; Omeprazole; Quinine; Rifampin

2008
Age-related differences in bitter taste and efficacy of bitter blockers.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Adult; Aging; Caffeine; Child; Child, Preschool; Female; Genotype; Gluconates; Humans; Male; Propylthiouracil; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Sodium Glutamate; Taste; Taste Buds

2014

Other Studies

126 other study(ies) available for caffeine and quinine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections.
    Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1

    Topics: Animals; Anti-Infective Agents; Carbazoles; Cerebellar Diseases; Indole Alkaloids; Mice; Microbial Sensitivity Tests; Molecular Structure; Neurogenic Inflammation; Porifera; Stereoisomerism; Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
    Chemical biology & drug design, 2016, Volume: 88, Issue:6

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain

2016
Mechanism of action of some bitter-tasting compounds on frog taste cells.
    The Japanese journal of physiology, 1976, Volume: 26, Issue:1

    Topics: Animals; Caffeine; Glossopharyngeal Nerve; Membrane Potentials; Quinine; Rana catesbeiana; Strychnine; Taste Buds; Urea

1976
Some antagonists of dantrolene sodium on the isolated diaphragm muscle of the rat.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:10

    Topics: Animals; Caffeine; Calcimycin; Dantrolene; Diaphragm; Electric Stimulation; Epinephrine; Female; Hydantoins; In Vitro Techniques; Male; Muscle Contraction; Pyridines; Quinine; Rats; Thiocyanates; Uranium

1977
Association of increased pHi with calcium ion release in skeletal muscle.
    The American journal of physiology, 1978, Volume: 234, Issue:3

    Topics: Animals; Anura; Caffeine; Calcium; Dantrolene; Dimethadione; Extracellular Space; Hydrogen-Ion Concentration; Insulin; Muscles; Procaine; Quinine; Rana pipiens; Sarcoplasmic Reticulum; Theophylline

1978
The effect of caffeine and quinine on calcium efflux and cyclic AMP levels in bovine ileal smooth muscle.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1978, Volume: 61 C, Issue:2

    Topics: Animals; Biological Transport; Caffeine; Calcium; Cattle; Cyclic AMP; Ileum; In Vitro Techniques; Muscle, Smooth; Quinine

1978
Biochemical studies of taste sensation: II. Labelling of cyclic AMP of bovine taste papillae in response to sweet and bitter stimuli.
    Journal of neuroscience research, 1976, Volume: 2, Issue:5-6

    Topics: Adenine; Animals; Caffeine; Cattle; Cyclic AMP; Epinephrine; Lactose; Quinine; Sucrose; Taste; Taste Buds; Theophylline

1976
The standardisation of thin-layer chromatographic systems for the identification of basic drugs.
    Journal of chromatography, 1975, Jul-16, Volume: 110, Issue:2

    Topics: Amitriptyline; Amphetamine; Caffeine; Chromatography, Thin Layer; Codeine; Hydrogen-Ion Concentration; Lidocaine; Meperidine; Pharmaceutical Preparations; Quinine; Silicon Dioxide; Solvents; Strychnine

1975
Calcium movements in bovine ileal smooth muscle [proceedings].
    Biochemical Society transactions, 1979, Volume: 7, Issue:3

    Topics: Animals; Biological Transport, Active; Caffeine; Calcium; Cattle; Ileum; Mitochondria; Quinine; Subcellular Fractions

1979
Rats drinking quinine- or caffeine-adulterated water defend lean body weights against caloric and osmotic stress.
    Physiology & behavior, 1978, Volume: 21, Issue:4

    Topics: Animal Feed; Animals; Body Weight; Caffeine; Cold Temperature; Drinking Behavior; Energy Intake; Feeding Behavior; Female; Male; Motor Activity; Osmolar Concentration; Quinine; Rats; Sodium Chloride; Stress, Physiological; Time Factors; Water

1978
An assay for inorganic orthophosphate in the presence of alkaloids and related drugs.
    Biochemical medicine, 1977, Volume: 17, Issue:2

    Topics: Alkaloids; Atropine; Caffeine; Methods; Molybdenum; Phosphates; Quinine; Theophylline

1977
[Amidoquine poisoning in children].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1976, Oct-15, Volume: 29, Issue:20

    Topics: Accidents, Home; Age Factors; Aminopyrine; Caffeine; Child, Preschool; Female; Humans; Infant; Male; Quinine

1976
[Determination of caffeine and quinine in the medicinal preparation Chinascorbin dragées by means of differential titration in non-aqueous medium].
    Ceskoslovenska farmacie, 1976, Volume: 25, Issue:10

    Topics: Caffeine; Drug Combinations; Potentiometry; Quinine; Solutions

1976
[Determination of anti-cold agents in pharmaceutical preparations by the dual-wavelength chromatoscanner (author's transl)].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1975, Issue:93

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Chromatography, Thin Layer; Common Cold; Drug Combinations; Quinine

1975
[Determination of Amidochin components following their separation by thin-layer chromatography].
    Acta poloniae pharmaceutica, 1975, Volume: 32, Issue:2

    Topics: Aminopyrine; Caffeine; Chromatography, Thin Layer; Colorimetry; Drug Combinations; Fluorometry; Quinine

1975
Effects of various drugs on calcium uptake by microsomes of rat submaxillary gland.
    Acta physiologica latino americana, 1975, Volume: 25, Issue:5

    Topics: Adenosine Triphosphate; Anesthetics; Animals; Caffeine; Calcium; Drug Evaluation; Microsomes; Quinine; Rats; Submandibular Gland

1975
Oral caffeine consumption by rats: the role of flavor history, concentration, concurrent food, and an adenosine agonist.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: Adenosine; Animals; Caffeine; Drinking Behavior; Feeding Behavior; Food; Male; Phenylisopropyladenosine; Quinine; Rats; Taste

1992
Carboxylic acid replacement structure-activity relationships in suosan type sweeteners. A sweet taste antagonist. 1.
    Journal of medicinal chemistry, 1992, May-15, Volume: 35, Issue:10

    Topics: Aspartic Acid; beta-Alanine; Caffeine; Carboxylic Acids; Flavanones; Flavonoids; Humans; Phenylurea Compounds; Quinine; Structure-Activity Relationship; Sweetening Agents; Taste

1992
Selective potentiation of subtetanic and tetanic contractions by the calcium-channel antagonist nifedipine in the rat diaphragm preparation.
    General pharmacology, 1991, Volume: 22, Issue:2

    Topics: Animals; Caffeine; Calcium; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Male; Membranes; Muscle Contraction; Nifedipine; Phenytoin; Potassium; Quinine; Rats; Rats, Inbred Strains; Respiratory Muscles

1991
A long lasting Ca2+-activated outward current in guinea-pig atrial myocytes.
    Pflugers Archiv : European journal of physiology, 1989, Volume: 415, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apamin; Atrial Function; Caffeine; Calcium; Calcium Channels; Cobalt; Electric Conductivity; Guinea Pigs; Heart; Kinetics; Nitrendipine; Potassium Channels; Quinine; Ryanodine

1989
Hypoxic changes in hippocampal neurons.
    Journal of neurophysiology, 1989, Volume: 62, Issue:1

    Topics: 4-Aminopyridine; Adenosine Triphosphate; Aminopyridines; Animals; Apamin; Caffeine; Calcium; Egtazic Acid; Electric Stimulation; Hippocampus; Hypoxia; Membrane Potentials; Neuroglia; Neuromuscular Depolarizing Agents; Neurons; Nitrogen; Quinine; Rats; Rats, Inbred Strains; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors; Tolbutamide

1989
A comparison of the actions of 4-aminopyridine, caffeine and quinine on the toad isolated rectus abdominis muscle.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1989, Volume: 92, Issue:1

    Topics: 4-Aminopyridine; Aminopyridines; Animals; Bufonidae; Caffeine; Egtazic Acid; In Vitro Techniques; Manganese; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Potassium; Procaine; Quinine; Verapamil

1989
Caffeine taste test for panic disorder: adenosine receptor supersensitivity.
    Psychiatry research, 1989, Volume: 30, Issue:3

    Topics: Adult; Anxiety Disorders; Arousal; Brain; Caffeine; Fear; Female; Humans; Male; Panic; Quinine; Receptors, Purinergic; Stress Disorders, Post-Traumatic; Taste; Taste Threshold

1989
Contribution of electrostatic and hydrophobic interactions of bitter substances with taste receptor membranes to generation of receptor potentials.
    Biochimica et biophysica acta, 1986, Aug-29, Volume: 888, Issue:1

    Topics: Adsorption; Animals; Caffeine; Cell Line; Electricity; In Vitro Techniques; Membrane Fluidity; Membrane Potentials; Mice; Osmolar Concentration; Quinine; Rana catesbeiana; Solubility; Strychnine; Taste; Taste Buds; Theophylline

1986
Effects of food deprivation on caffeine consumption in male and female rats.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:6

    Topics: Analysis of Variance; Animals; Body Weight; Caffeine; Female; Food Deprivation; Male; Quinine; Rats; Sex Factors

1986
Drugs in breast milk.
    The Medical letter on drugs and therapeutics, 1974, Mar-15, Volume: 16, Issue:6

    Topics: Anticoagulants; Anticonvulsants; Antineoplastic Agents; Antithyroid Agents; Aspirin; Atropine; Caffeine; Chloramphenicol; Chlorothiazide; Contraceptives, Oral; Ergot Alkaloids; Ethanol; Female; Humans; Hypnotics and Sedatives; Methadone; Milk, Human; Nalidixic Acid; Narcotics; Penicillins; Quinine; Reserpine; Sulfonamides; Tetracycline

1974
[Reaction with drugs of basophilic structures in young red blood cells].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Animals; Atropine; Caffeine; Guinea Pigs; Heinz Bodies; Microscopy, Electron; Morphine; Organoids; Phenylhydrazines; Quinine; Reticulocytes; Ribosomes

1967
Interaction of cations and local anesthetics with isolated sarcolemma.
    Biochimica et biophysica acta, 1972, Jun-20, Volume: 266, Issue:3

    Topics: Actomyosin; Adenosine Triphosphatases; Anesthetics, Local; Animals; Binding Sites; Caffeine; Calcium; Chlorpromazine; Enzyme Activation; Lipids; Magnesium; Mathematics; Procaine; Protein Binding; Protons; Quinine; Rabbits; Sarcolemma; Spectrophotometry, Atomic; Tetracaine; Zinc

1972
Inhibition of cyclic 3',5'-nucleotide phosphodiesterase in bovine taste papillae by bitter taste stimuli.
    FEBS letters, 1972, Nov-01, Volume: 27, Issue:2

    Topics: Animals; Bacitracin; Binding, Competitive; Caffeine; Cattle; Cyclic AMP; Epithelium; In Vitro Techniques; Kinetics; Papaverine; Phosphodiesterase Inhibitors; Quinine; Strychnine; Taste; Taste Buds; Theobromine; Theophylline

1972
[Comparative study on quantitative determination of mixtures of analgesics. 1. Studies on selectivity of volumetric analysis procedures].
    Die Pharmazie, 1974, Volume: 29, Issue:7

    Topics: Acetaminophen; Aminopyrine; Analgesics; Ascorbic Acid; Aspirin; Barbiturates; Caffeine; Chlorpromazine; Codeine; Conductometry; Electrochemistry; Meprobamate; Mesylates; Methods; Papaverine; Phenacetin; Phenobarbital; Phenylbutazone; Potentiometry; Quinine; Salicylamides; Salicylates; Theobromine

1974
[Drug permeation through synthetic lipid membranes. Permeability of lecithin-collodium membranes for drugs and metabolites].
    Die Pharmazie, 1974, Volume: 29, Issue:9

    Topics: Buffers; Caffeine; Diffusion; Hexobarbital; Hydrogen-Ion Concentration; Kinetics; Membranes, Artificial; Models, Chemical; Papaverine; Phenobarbital; Phenytoin; Phosphatidylcholines; Quinine; Salicylates; Solutions; Time Factors

1974
Chlorpromazine-induced contracture of frog rectus abdominis muscle.
    Pharmacology, 1974, Volume: 12, Issue:1

    Topics: Acetylcholine; Adenosine; Animals; Arsenic; Atropine; Caffeine; Chlorpromazine; Choline; Cocaine; Cyanides; Electric Stimulation; Fluorides; Hexamethonium Compounds; In Vitro Techniques; Iodoacetates; Muscle Contraction; Ouabain; Physostigmine; Potassium Chloride; Procaine; Quinine; Sparteine; Stimulation, Chemical; Tubocurarine

1974
[Stability of alkaloids in organic solvents. 1].
    Die Pharmazie, 1972, Volume: 27, Issue:10

    Topics: Acetone; Alkaloids; Atropine; Benzene; Caffeine; Chloroform; Codeine; Darkness; Drug Stability; Ethanol; Light; Methanol; Morphine; Noscapine; Papaverine; Physostigmine; Pilocarpine; Quinine; Radiation; Reserpine; Scopolamine; Solvents; Temperature; Thebaine

1972
Mechanism of bitter taste reception: interaction of bitter compounds with monolayers of lipids from bovine circumvallate papillae.
    Biochimica et biophysica acta, 1972, Oct-23, Volume: 288, Issue:1

    Topics: Anilides; Animals; Caffeine; Cattle; Flavonoids; Formaldehyde; Formamides; Glycosides; Lipids; Membranes, Artificial; Methyl Ethers; Nicotine; Picrates; Quinine; Sensory Receptor Cells; Strychnine; Surface Tension; Taste Buds; Theobromine; Urea

1972
Ionic polymerisation as a means of end-point indication in non-aqueous thermometric titrimetry. 3. The determination of alkaloids and alkaloidal salts.
    The Analyst, 1973, Volume: 98, Issue:163

    Topics: Alkaloids; Atropine; Caffeine; Codeine; Ephedrine; Indicators and Reagents; Methods; Microchemistry; Nicotine; Papaverine; Polymers; Quinine; Salts; Strychnine; Temperature; Theophylline

1973
Contractile calcium in rabbit myocardium: observations with nicotine and quinine.
    The American journal of physiology, 1973, Volume: 224, Issue:5

    Topics: Animals; Biomechanical Phenomena; Buffers; Caffeine; Calcium; Calcium Isotopes; Heart Septum; Hydrogen-Ion Concentration; Lanthanum; Muscle Contraction; Myocardium; Nicotine; Perfusion; Quinine; Rabbits; Reserpine

1973
Sites of action of Lilly 18947 in skeletal muscle.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2

    Topics: Animals; Anura; Binding Sites; Biphenyl Compounds; Caffeine; Calcium; Calcium Isotopes; Chlorides; Electric Stimulation; Ethylamines; In Vitro Techniques; Membrane Potentials; Microsomes, Liver; Muscle Contraction; Muscles; Osmolar Concentration; Oxidoreductases; Procaine; Quinine; Sarcoplasmic Reticulum; Time Factors

1973
TLC separation of drug alkaloids.
    Journal of chemical education, 1974, Volume: 51, Issue:1

    Topics: Alkaloids; Caffeine; Chromatography, Thin Layer; Methods; Quinine; Strychnine

1974
[Pharmacological studies on the vascular system of the human placenta].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:2

    Topics: Acetylcholine; Atropine; Blood Vessels; Caffeine; Carbon Dioxide; Ephedrine; Epinephrine; Ergotamine; Female; Histamine; Humans; Isoproterenol; Nicotine; Norepinephrine; Oxygen; Oxytocin; Papaverine; Perfusion; Phenoxybenzamine; Pilocarpine; Placenta; Pregnancy; Propranolol; Quinine; Serotonin

1974
Superprecipitation of actomyosin extracted from crayfish skeletal muscle: the effect of heavy metal cations, EDTA and drugs.
    The Journal of experimental zoology, 1971, Volume: 177, Issue:4

    Topics: Adenosine Triphosphate; Animals; Astacoidea; Binding Sites; Cadmium; Caffeine; Calcium; Chemical Precipitation; Drug Synergism; Edetic Acid; Magnesium; Metals; Muscle Contraction; Muscle Proteins; Muscles; Myofibrils; Quinine; Spectrophotometry; Strontium; Time Factors; Zinc

1971
[2 cases of fatal poisoning with amidochin in small children].
    Przeglad lekarski, 1971, Volume: 28, Issue:5

    Topics: Accidents, Home; Aminopyrine; Autopsy; Brain Edema; Caffeine; Child, Preschool; Female; Humans; Poisoning; Pulmonary Edema; Quinine; Time Factors

1971
[Pretesting of drugs using lower and higher plants. II. Effect of phenazetin and various substances frequently combined with it, on the shape and growth of Micrasterias americana].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:6

    Topics: Antineoplastic Agents; Biological Assay; Caffeine; Cell Division; Cell Transformation, Neoplastic; Drug Synergism; Eukaryota; Phenacetin; Phenobarbital; Quinine

1971
Haemoglobinuria in Nigerian children.
    The African journal of medical sciences, 1971, Volume: 2, Issue:2

    Topics: Acetaminophen; Aspirin; Autopsy; Brain; Caffeine; Child; Child, Preschool; Coombs Test; Diagnosis, Differential; Erythrocytes; Female; Genotype; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Hemoglobinuria; Humans; Infant; Kidney; Liver; Malaria; Male; Nigeria; Phenacetin; Quinine; Sex Factors; Spleen; Sulfonamides

1971
Contracture and twitch potentiation of fast and slow muscles of the rat at 20 and 37 C.
    The American journal of physiology, 1970, Volume: 218, Issue:1

    Topics: Animals; Anura; Caffeine; Male; Muscle Contraction; Muscles; Nitrates; Physiology, Comparative; Procaine; Quinine; Rats; Temperature; Zinc

1970
Quinine contractures and Ca45 movements of frog sartorius muscles as affected by pH.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 171, Issue:1

    Topics: Animals; Anura; Caffeine; Calcium; Calcium Isotopes; Endoplasmic Reticulum; Hydrogen-Ion Concentration; Muscle Contraction; Muscles; Procaine; Quinine

1970
The effects of potentiators and of anticholinesterases on the kinetics of calcium uptake by isolated sarcoplasmic reticulum from the lobster and the rat.
    Comparative and general pharmacology, 1970, Volume: 1, Issue:2

    Topics: Acetyltransferases; Animals; Caffeine; Calcium; Choline; Cholinesterase Inhibitors; Cholinesterases; Dithiothreitol; Drug Synergism; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Muscle Contraction; Muscles; Nephropidae; Quinine; Rats; Sarcoplasmic Reticulum; Spectrophotometry; Temperature

1970
The in vitro sensitivity of erythrocyte aggregation to quinine: assessment by a serial blood sedimentation procedure.
    Clinical chemistry, 1971, Volume: 17, Issue:1

    Topics: Animals; Blood Flow Velocity; Blood Sedimentation; Caffeine; Erythrocyte Aggregation; Erythrocytes; Horses; In Vitro Techniques; Quinine; Temperature; Time Factors

1971
The effect of quinine on tension development, membrane potentials and excitation-contraction coupling of crab skeletal muscle fibres.
    The Journal of physiology, 1971, Volume: 216, Issue:3

    Topics: Action Potentials; Animals; Caffeine; Calcium; Crustacea; Endoplasmic Reticulum; Membrane Potentials; Muscle Contraction; Muscles; Myofibrils; Potassium; Quinine

1971
Effects of phenyl benzo-gamma-pyrone derivatives (flavonoids) on blood cell aggregation: basis for a concept of mode of action.
    Clinical chemistry, 1971, Volume: 17, Issue:5

    Topics: Animals; Blood Sedimentation; Caffeine; Capillary Fragility; Capillary Permeability; Cell Aggregation; Depression, Chemical; Dextrans; Erythrocytes; Flavonoids; Horses; Molecular Weight; Quinine; Rutin

1971
On the increase in rate of heat production caused by stretch in frog's skeletal muscle.
    The Journal of physiology, 1968, Volume: 196, Issue:2

    Topics: Animals; Anura; Body Temperature Regulation; Caffeine; Carbon Dioxide; Electrophysiology; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Methods; Muscles; Procaine; Quinine; Sarcolemma; Sodium Chloride; Species Specificity; Sulfates; Thiocyanates; Zinc

1968
[Separation and identification of components of drugs containing salicylamide by means of paper chromatography].
    Acta poloniae pharmaceutica, 1968, Volume: 25, Issue:2

    Topics: Aminobenzoates; Aspirin; Caffeine; Chromatography, Paper; Pharmaceutical Preparations; Phenacetin; Quinine; Salicylamides

1968
Calcium-binding properties of sarcoplasmic reticulum as influenced by ATP, caffeine, quinine, and local anesthetics.
    The Journal of general physiology, 1968, Volume: 52, Issue:4

    Topics: Adenosine Triphosphate; Animals; Binding Sites; Caffeine; Calcium; Cell Membrane; Magnesium; Muscles; Potassium; Procaine; Quinine; Rabbits; Radioisotopes; Spectrum Analysis; Tetracaine

1968
Interactions between pharmaceutical compounds by thermal methods.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:3

    Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K

1969
[Non-aqueous titration of pentetrazole and its determination in drug mixtures].
    Die Pharmazie, 1969, Volume: 24, Issue:3

    Topics: Caffeine; Electrodes; Ephedrine; Methods; Morphinans; Pentylenetetrazole; Quinine

1969
Quinine and caffeine effects on 45Ca movements in frog sartorius muscle.
    The Journal of general physiology, 1967, Volume: 50, Issue:8

    Topics: Action Potentials; Animals; Anura; Caffeine; Calcium; Calcium Isotopes; Endoplasmic Reticulum; Muscle Contraction; Muscles; Potassium; Quinine; Water-Electrolyte Balance

1967
The adaptation of the frog tongue to various taste solutions: the effect on gustatory neural responses to bitter stimuli.
    Comparative biochemistry and physiology. A, Comparative physiology, 1982, Volume: 73, Issue:3

    Topics: Adaptation, Physiological; Animals; Caffeine; Carbohydrates; Picrates; Quinine; Rana catesbeiana; Salts; Strychnine; Taste; Taste Buds

1982
Mechanism and function of the Ca2+-gated cation channel in sarcoplasmic reticulum vesicles.
    Journal of biochemistry, 1982, Volume: 92, Issue:2

    Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Choline; Cobalt; Dicyclohexylcarbodiimide; In Vitro Techniques; Ion Channels; Kinetics; Magnesium; Muscles; Quinine; Rabbits; Sarcoplasmic Reticulum

1982
Inhibitory effects of salicylate on contractility in skeletal muscle.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2

    Topics: Animals; Bufo marinus; Caffeine; Calcium; Hydrogen-Ion Concentration; Membrane Potentials; Muscle Contraction; Potassium; Quinine; Ranidae; Salicylamides; Salicylates; Salicylic Acid

1984
[Simultaneous determination of quinine hydrochloride, phenacetin and caffeine in mixtures using spectrophotometry].
    Bollettino chimico farmaceutico, 1984, Volume: 123, Issue:11

    Topics: Caffeine; Drug Combinations; Phenacetin; Quinine; Spectrophotometry, Ultraviolet

1984
Caffeine and quinine increase the release of sarcoplasmic enzymes from frog skeletal muscles.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1982, Volume: 15, Issue:1

    Topics: Animals; Anura; Caffeine; Creatine Kinase; L-Lactate Dehydrogenase; Muscle Contraction; Muscles; Procaine; Quinine; Rana pipiens; Temperature

1982
Antimycotic activity of some alkaloidal salts.
    Mykosen, 1981, Volume: 24, Issue:7

    Topics: Alkaloids; Animals; Caffeine; Citrates; Drug Combinations; Drug Evaluation, Preclinical; Female; Guinea Pigs; Male; Mitosporic Fungi; Mucorales; Quinine; Tinea; Yeasts

1981
Characterization of the methylxanthine-induced propagated wave phenomenon in striated muscle.
    The Journal of experimental zoology, 1980, Volume: 212, Issue:3

    Topics: Animals; Caffeine; Chick Embryo; Halothane; Histocytochemistry; Muscle Contraction; Muscles; Quinine; Theobromine; Theophylline

1980
Selective inhibition of bitter taste of various drugs by lipoprotein.
    Pharmaceutical research, 1995, Volume: 12, Issue:5

    Topics: Caffeine; Chemistry, Pharmaceutical; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Excipients; Humans; Lactoglobulins; Lipoproteins; Phosphatidic Acids; Phosphatidylcholines; Quinine; Serum Albumin, Bovine; Sodium Chloride; Sucrose; Taste; Taste Threshold; Triglycerides

1995
Pharmacological characterization of muscarinic receptor-activated cation channels in guinea-pig ileum.
    British journal of pharmacology, 1993, Volume: 109, Issue:3

    Topics: 4-Aminopyridine; Acetylcholine; Animals; Caffeine; Calcium Channels; Diphenylamine; Egtazic Acid; Electrophysiology; Female; Flufenamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Muscle, Smooth; Nystatin; Procaine; Quinine; Receptors, Muscarinic; Tetraethylammonium Compounds

1993
Gustatory control of feeding behavior in goldfish.
    Physiology & behavior, 1995, Volume: 57, Issue:3

    Topics: Amino Acids; Animals; Caffeine; Eating; Feeding Behavior; Goldfish; Quinine; Taste; Vagus Nerve

1995
Caffeine potentiation of taste in panic-disorder patients.
    Biological psychiatry, 1993, Feb-01, Volume: 33, Issue:3

    Topics: Adult; Agoraphobia; Caffeine; Drug Synergism; Female; Humans; Male; Middle Aged; Panic Disorder; Quinine; Taste Threshold

1993
Suppression of bitterness by sodium: variation among bitter taste stimuli.
    Chemical senses, 1995, Volume: 20, Issue:6

    Topics: Adult; Amiloride; Anions; Caffeine; Cations; Drug Interactions; Humans; Lithium Chloride; Magnesium Sulfate; Potassium Chloride; Quinine; Sodium; Sodium Chloride; Taste; Urea

1995
Response of pigs to bitter-tasting compounds.
    Chemical senses, 1997, Volume: 22, Issue:2

    Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Male; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Quinine; Random Allocation; Reference Standards; Sucrose; Swine; Swine, Miniature; Taste; Water

1997
Quinine suppression of single facial taste fiber responses in the channel catfish.
    Brain research, 1997, Sep-26, Volume: 769, Issue:2

    Topics: Amino Acids; Animals; Caffeine; Electrophysiology; Face; Ictaluridae; Nerve Fibers; Quaternary Ammonium Compounds; Quinine; Stimulation, Chemical; Taste

1997
Establishing oral preference for quinine, phencyclidine and caffeine solutions in rats.
    Behavioural pharmacology, 1999, Volume: 10, Issue:1

    Topics: Animals; Antimalarials; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking Behavior; Excitatory Amino Acid Antagonists; Male; Phencyclidine; Quinine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Taste

1999
Characterization of an intense bitter-tasting 1H,4H-quinolizinium-7-olate by application of the taste dilution analysis, a novel bioassay for the screening and identification of taste-active compounds in foods.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:1

    Topics: Caffeine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Food; Food Analysis; Humans; Magnetic Resonance Spectroscopy; Maillard Reaction; Mass Spectrometry; Quinine; Quinolizines; Taste

2001
[Abortive treatment of influenzal infections with pleon].
    Munchener medizinische Wochenschrift (1950), 1953, Oct-23, Volume: 95, Issue:43

    Topics: Analgesics; Biomedical Research; Caffeine; Humans; Influenza, Human; Quinine; Sulfasalazine

1953
[Changes in action potential of striated muscle fibers induced by caffeine and quinine].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1957, Volume: 151, Issue:3

    Topics: Action Potentials; Caffeine; Humans; Muscle Cells; Muscle Fibers, Skeletal; Muscles; Quinine

1957
Common drugs that may invalidate spectrophotofluorometric assays of blood griseofulvin.
    The Journal of pharmacy and pharmacology, 1962, Volume: 14

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biological Assay; Caffeine; Griseofulvin; Humans; Quinine; Theophylline

1962
Separation of tabletted mixtures of barbiturates, aspirin, phenacetin, caffeine, codeine, and quinine by ion-exchange paper chromatography.
    Journal of pharmaceutical sciences, 1962, Volume: 51

    Topics: Aspirin; Barbiturates; Caffeine; Chromatography; Chromatography, Ion Exchange; Chromatography, Paper; Codeine; Ion Exchange Resins; Phenacetin; Quinine; Tablets

1962
Interaction of carrageenan and other hydrocolloids with alkaloids. II. Equilibrium dialysis studies.
    Journal of pharmaceutical sciences, 1962, Volume: 51

    Topics: Acacia; Alkaloids; Atropa belladonna; Caffeine; Carrageenan; Colloids; Dialysis; Methylcellulose; Parasympatholytics; Pectins; Polysaccharides; Quinine; Renal Dialysis; Resins, Synthetic; Theophylline

1962
BIODYNAMICS OF THIOUREA-ALKALOID COMBINATIONS.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 141

    Topics: Absorption; Alkaloids; Anti-Bacterial Agents; Blood Chemical Analysis; Caffeine; Intestines; Metabolism; Penicillins; Pharmacology; Quinidine; Quinine; Rats; Research; Salicylic Acid; Thiourea

1963
[OBSERVATION OF A CASE OF ACUTE HEMOLYTIC ANEMIA RELATED TO A GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY].
    Acta paediatrica Belgica, 1963, Volume: 17

    Topics: Aminopyrine; Anemia; Anemia, Hemolytic; Caffeine; Child; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Humans; Phenacetin; Quinine; Toxicology

1963
[ANALYSIS OF GALENIC PREPARATIONS. QUINA-KOLA SYRUP].
    Bollettino chimico farmaceutico, 1964, Volume: 103

    Topics: Caffeine; Chemistry, Pharmaceutical; Cinchona; Pharmacy; Quinidine; Quinine; Research

1964
[THE DETERMINATION OF THE CAFFEINE, QUININE AND STRYCHNINE CONTENT OF SYRUP OF KOLA BY MEANS OF ION EXCHANGE RESINS].
    Pharmaceutisch weekblad, 1964, Oct-02, Volume: 99

    Topics: Caffeine; Chemistry, Pharmaceutical; Cinchona; Food; Ion Exchange Resins; Pharmacy; Plants, Medicinal; Quinine; Research; Strychnine

1964
The distinctiveness of ionic and nonionic bitter stimuli.
    Physiology & behavior, 2004, Volume: 80, Issue:4

    Topics: Animals; Avoidance Learning; Caffeine; Cricetinae; Generalization, Psychological; Humans; Ions; Lithium Chloride; Male; Mesocricetus; Quaternary Ammonium Compounds; Quinine; Species Specificity; Structure-Activity Relationship; Sucrose; Taste; Taste Buds; Taste Threshold

2004
Variation in intake of sweet and bitter solutions by inbred strains of golden hamsters.
    Behavior genetics, 2004, Volume: 34, Issue:4

    Topics: Analysis of Variance; Animals; Caffeine; Cricetinae; Crosses, Genetic; Drinking Behavior; Female; Inbreeding; Male; Mesocricetus; Quinine; Sucrose; Taste

2004
Two antagonistic gustatory receptor neurons responding to sweet-salty and bitter taste in Drosophila.
    Journal of neurobiology, 2004, Volume: 61, Issue:3

    Topics: Action Potentials; Adaptation, Physiological; Animals; Behavior, Animal; Berberine; Caffeine; Dose-Response Relationship, Drug; Drinking Behavior; Drosophila; Drosophila Proteins; Drug Interactions; Female; Male; Neurons; Quinine; Receptors, Cell Surface; Sex Factors; Sodium Chloride; Strychnine; Sucrose; Taste; Time Factors

2004
Heritability and genetic covariation of sensitivity to PROP, SOA, quinine HCl, and caffeine.
    Chemical senses, 2006, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Caffeine; Child; Female; Genetic Variation; Humans; Inheritance Patterns; Male; Models, Genetic; Phenotype; Propylthiouracil; Quinine; Sensitivity and Specificity; Siblings; Sucrose; Taste; Twins, Dizygotic; Twins, Monozygotic

2006
Skin permeation enhancement potential of Aloe Vera and a proposed mechanism of action based upon size exclusion and pull effect.
    International journal of pharmaceutics, 2007, Mar-21, Volume: 333, Issue:1-2

    Topics: Aloe; Animals; Caffeine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Colchicine; Diffusion Chambers, Culture; Drug Carriers; Excipients; Gels; Mandelic Acids; Mefenamic Acid; Molecular Weight; Organ Culture Techniques; Permeability; Plant Extracts; Quinine; Skin; Skin Absorption; Solubility; Swine; Time Factors; Water

2007
A complex relationship among chemical concentration, detection threshold, and suprathreshold intensity of bitter compounds.
    Chemical senses, 2007, Volume: 32, Issue:3

    Topics: Adult; Caffeine; Dose-Response Relationship, Drug; Female; Humans; Male; Propylthiouracil; Quinine; Taste Threshold

2007
Riboflavin-binding protein is a novel bitter inhibitor.
    Chemical senses, 2008, Volume: 33, Issue:1

    Topics: Acid Phosphatase; Adult; Caffeine; Dipeptides; Egg White; Egg Yolk; Female; Flavanones; Humans; Lactoglobulins; Male; Membrane Transport Proteins; Ovalbumin; Protein Binding; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Serum Albumin, Bovine; Taste; Theobromine

2008
Structural analogues of homoeriodictyol as flavor modifiers. Part III: short chain gingerdione derivatives.
    Journal of agricultural and food chemistry, 2008, Aug-13, Volume: 56, Issue:15

    Topics: Benzyl Alcohols; Caffeine; Carbohydrates; Flavones; Flavoring Agents; Glucosides; Guaiacol; Quinine; Structure-Activity Relationship; Taste

2008
Gustatory responsiveness to six bitter tastants in three species of nonhuman primates.
    Journal of chemical ecology, 2009, Volume: 35, Issue:5

    Topics: Animals; Atelinae; Behavior, Animal; Benzyl Alcohols; Caffeine; Choice Behavior; Flavanones; Food Preferences; Glucosides; Macaca nemestrina; Primates; Quaternary Ammonium Compounds; Quinine; Saimiri; Species Specificity; Sucrose; Taste; Taste Threshold

2009
A Drosophila gustatory receptor essential for aversive taste and inhibiting male-to-male courtship.
    Current biology : CB, 2009, Oct-13, Volume: 19, Issue:19

    Topics: Analysis of Variance; Animals; Caffeine; DNA Primers; Drosophila; Drosophila Proteins; Electrophysiology; Genetic Vectors; Immunohistochemistry; In Situ Hybridization, Fluorescence; Lobeline; Male; Oligonucleotide Array Sequence Analysis; Phylogeny; Quinine; Receptors, Cell Surface; Sexual Behavior, Animal; Taste

2009
Limited taste discrimination in Drosophila.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Aug-17, Volume: 107, Issue:33

    Topics: Animals; Behavior, Animal; Berberine; Caffeine; Conditioning, Psychological; Discrimination, Psychological; Dose-Response Relationship, Drug; Drosophila melanogaster; Food Preferences; Fructose; Glucose; Maltose; Quinine; Taste

2010
Consumption of bitter alkaloids in Drosophila melanogaster in multiple-choice test conditions.
    Chemical senses, 2011, Volume: 36, Issue:4

    Topics: Alkaloids; Animals; Caffeine; Drosophila melanogaster; Drosophila Proteins; Electrophysiology; Food Preferences; Mutation; Quinine; Receptors, Cell Surface; Taste

2011
The sugar meal of the African malaria mosquito Anopheles gambiae and how deterrent compounds interfere with it: a behavioural and neurophysiological study.
    The Journal of experimental biology, 2013, Apr-01, Volume: 216, Issue:Pt 7

    Topics: Action Potentials; Analysis of Variance; Animals; Anopheles; Berberine; Caffeine; Chemoreceptor Cells; Feeding Behavior; Female; Fructose; Glucose; Microscopy, Electron, Transmission; Nigeria; Quaternary Ammonium Compounds; Quinidine; Quinine; Sensilla; Sucrose

2013
New protocol for αAstree electronic tongue enabling full performance qualification according to ICH Q2.
    Journal of pharmaceutical and biomedical analysis, 2013, Volume: 83

    Topics: Biosensing Techniques; Caffeine; Citrates; Drug Industry; Electronics; Quinine; Taste; Technology, Pharmaceutical; Tongue

2013
Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity.
    British journal of pharmacology, 2014, Volume: 171, Issue:3

    Topics: Airway Resistance; Animals; Bronchodilator Agents; Caffeine; Calcium Channel Blockers; Calcium Signaling; Chloroquine; Drug Resistance; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lung; Mice; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Ryanodine; Taste

2014
Effects of Teratogenic Drugs on CYP1A1 Activity in Differentiating Rat Embryo Cells.
    Drug research, 2015, Volume: 65, Issue:5

    Topics: Animals; Caffeine; Cell Differentiation; Cells, Cultured; Cytochrome P-450 CYP1A1; Embryo, Mammalian; Hydrocortisone; Limb Buds; Quinine; Rats; Teratogens; Tretinoin

2015
"A spoonful of sugar helps the medicine go down": bitter masking by sucrose among children and adults.
    Chemical senses, 2015, Volume: 40, Issue:1

    Topics: Adult; Caffeine; Child; Child, Preschool; Female; Genotype; Heterozygote; Humans; Male; Propylthiouracil; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Sucrose; Taste Threshold; Urea

2015
The impact of individual variations in taste sensitivity on coffee perceptions and preferences.
    Physiology & behavior, 2015, Volume: 138

    Topics: Adult; Caffeine; Coffee; Dietary Sucrose; Female; Food Preferences; Humans; Hydrochloric Acid; Male; Middle Aged; Propylthiouracil; Psychophysics; Quinine; Taste Perception; Taste Threshold; Tongue; Young Adult

2015
[CAFFEINE AND QUININE IN SOFT DRINKS; CONTRIBUTION TO THE DIETARY INTAKE].
    Nutricion hospitalaria, 2015, Dec-01, Volume: 32, Issue:6

    Topics: Caffeine; Carbonated Beverages; Chromatography, High Pressure Liquid; Diet; Quinine

2015
Habituation in non-neural organisms: evidence from slime moulds.
    Proceedings. Biological sciences, 2016, 04-27, Volume: 283, Issue:1829

    Topics: Animals; Biological Evolution; Caffeine; Chemotaxis; Habituation, Psychophysiologic; Learning; Models, Biological; Phylogeny; Physarum polycephalum; Quinine

2016
Kissing bugs can generalize and discriminate between different bitter compounds.
    Journal of physiology, Paris, 2016, Volume: 110, Issue:3 Pt A

    Topics: Animals; Avoidance Learning; Behavior, Animal; Caffeine; Conditioning, Psychological; Learning; Quinine; Rhodnius; Taste

2016
Binding of Caffeine and Quinine by Whey Protein and the Effect on Bitterness.
    Journal of food science, 2017, Volume: 82, Issue:2

    Topics: Caffeine; Chromatography, High Pressure Liquid; Computer Simulation; Humans; Lactoglobulins; Models, Molecular; Nitrogen; Quinine; Saliva; Taste; Taste Perception; Thermodynamics; Whey Proteins

2017
From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds.
    Molecules (Basel, Switzerland), 2017, May-17, Volume: 22, Issue:5

    Topics: Animals; Avoidance Learning; Beak; Caffeine; Catechin; Chickens; Erythromycin; Gene Expression; HEK293 Cells; Humans; Ligands; Nicotine; Quinine; Receptors, G-Protein-Coupled; Taste Threshold; Transfection

2017
Odor-Cued Bitter Taste Avoidance.
    Chemical senses, 2018, 04-23, Volume: 43, Issue:4

    Topics: Animals; Aversive Agents; Avoidance Learning; Caffeine; Cues; Female; Mice; Olfactory Bulb; Propylthiouracil; Quaternary Ammonium Compounds; Quinine; Smell; Sucrose; Taste

2018
Detection of Cutting Agents in Drug-Positive Seized Exhibits within the United States.
    Journal of forensic sciences, 2019, Volume: 64, Issue:3

    Topics: Acetaminophen; Caffeine; Chromatography, Liquid; Drug Contamination; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Kentucky; Levamisole; Procaine; Quinidine; Quinine; Vermont

2019
Associations between brain structure and perceived intensity of sweet and bitter tastes.
    Behavioural brain research, 2019, 05-02, Volume: 363

    Topics: Adult; Australia; Aversive Agents; Brain; Caffeine; Connectome; Female; Humans; Male; Propylthiouracil; Quinine; Sucrose; Sweetening Agents; Taste; Taste Perception

2019
Bitter Taste Perception of the Human Tongue Mediated by Quinine and Caffeine Impregnated Taste Strips.
    The Annals of otology, rhinology, and laryngology, 2020, Volume: 129, Issue:8

    Topics: Adult; Caffeine; Female; Healthy Volunteers; Humans; Male; Quinine; Taste; Taste Disorders; Taste Perception; Tongue; Young Adult

2020
Chronic voluntary caffeine intake in male Wistar rats reveals individual differences in addiction-like behavior.
    Pharmacology, biochemistry, and behavior, 2020, Volume: 191

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Choice Behavior; Dose-Response Relationship, Drug; Individuality; Irritable Mood; Male; Nociception; Quinine; Rats; Rats, Wistar; Substance Withdrawal Syndrome

2020
Impact of alkaloids in food consumption, metabolism and survival in a blood-sucking insect.
    Scientific reports, 2020, 06-10, Volume: 10, Issue:1

    Topics: Alkaloids; Animals; Caffeine; Digestion; Eating; Feeding Behavior; Insecta; Quinine; Reduviidae; Rhodnius; Taste

2020
Partitioning of caffeine and quinine in oil-in-water emulsions and effects on bitterness.
    Journal of food science, 2023, Volume: 88, Issue:S1

    Topics: Caffeine; Emulsions; Humans; Quinine; Taste; Water; Whey Proteins

2023
Exploiting natural riboswitches for aptamer engineering and validation.
    Nucleic acids research, 2023, 01-25, Volume: 51, Issue:2

    Topics: Aptamers, Nucleotide; Caffeine; Genetic Engineering; Guanine; Ligands; Nucleic Acid Conformation; Quinine; Riboswitch

2023
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