caffeine and propylthiouracil

caffeine has been researched along with propylthiouracil in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (7.41)	18.7374
1990's	2 (7.41)	18.2507
2000's	8 (29.63)	29.6817
2010's	15 (55.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Avdeef, A; Tam, KY	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cannell, GR; Mortimer, RH; Williams, JP; Yap, AS	1
Varrone, S; Wolff, J	1
Dumont, JE; Van Sande, J	1
Louis-Sylvestre, J; Smagghe, K	1
Drewnowski, A; Ly, A	1
Breslin, PA; Hansen, JL; Martin, NG; Reed, DR; Wright, MJ	1
Keast, RS; Roper, J	1
Mansfield, CJ; Mathew, PS; Mennella, JA; Reed, DR; Roberts, KM	2
Dinnella, C; Masi, C; Monteleone, E; Prescott, J	1
Aragoni, MC; Arca, M; Cabras, T; Caltagirone, C; Castagnola, M; Crnjar, R; Melis, M; Messana, I; Tepper, BJ; Tomassini Barbarossa, I	1
Coppola, DM; Slotnick, B	1
Breslin, PAS; Couvy-Duchesne, B; de Zubicaray, GI; Hwang, LD; Martin, NG; McMahon, K; Reed, DR; Strike, LT; Wright, MJ	1

Reviews

1 review(s) available for caffeine and propylthiouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for caffeine and propylthiouracil

Article	Year
Age-related differences in bitter taste and efficacy of bitter blockers. PloS one, 2014, Volume: 9, Issue:7 Topics: Adult; Aging; Caffeine; Child; Child, Preschool; Female; Genotype; Gluconates; Humans; Male; Propylthiouracil; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Sodium Glutamate; Taste; Taste Buds	2014

Other Studies

25 other study(ies) available for caffeine and propylthiouracil

Article	Year
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Selective liquid chromatographic assay for propylthiouracil in plasma. Journal of chromatography, 1991, Mar-08, Volume: 564, Issue:1 Topics: Caffeine; Chloroform; Chromatography, High Pressure Liquid; Half-Life; Humans; Propylthiouracil	1991
The methyl xanthines--a new class of goitrogens. Endocrinology, 1969, Volume: 85, Issue:3 Topics: Aminophylline; Animals; Antithyroid Agents; Blood Proteins; Caffeine; Cyclic AMP; Drug Synergism; Goiter; Hypophysectomy; In Vitro Techniques; Iodine; Male; Propylthiouracil; Protein Binding; Rats; Theobromine; Theophylline; Thyroid Gland	1969
Effects of thyrotropin, prostaglandin E1 and iodide on cyclic 3',5'-AMP concentration in dog thyroid slices. Biochimica et biophysica acta, 1973, Jul-28, Volume: 313, Issue:2 Topics: Animals; Caffeine; Calcium; Cyclic AMP; Dogs; In Vitro Techniques; Iodides; Iodine Radioisotopes; Methimazole; Perchlorates; Phosphodiesterase Inhibitors; Potassium; Propylthiouracil; Prostaglandins; Sodium; Thyroid Gland; Thyrotropin; Time Factors; Tritium	1973
Influence of PROP-sensitivity on taste perceptions and hedonics in French women. A study performed without retronasal olfaction. Appetite, 1998, Volume: 30, Issue:3 Topics: Adult; Caffeine; Female; Humans; Perception; Propylthiouracil; Saccharin; Smell; Sodium Chloride; Solutions; Sucrose; Taste Threshold	1998
PROP (6-n-Propylthiouracil) tasting and sensory responses to caffeine,sucrose, neohesperidin dihydrochalcone and chocolate. Chemical senses, 2001, Volume: 26, Issue:1 Topics: Adolescent; Adult; Cacao; Caffeine; Chalcone; Chalcones; Eating; Female; Food Preferences; Hesperidin; Humans; Propylthiouracil; Solutions; Sucrose; Sweetening Agents; Taste	2001
Heritability and genetic covariation of sensitivity to PROP, SOA, quinine HCl, and caffeine. Chemical senses, 2006, Volume: 31, Issue:5 Topics: Adolescent; Adult; Caffeine; Child; Female; Genetic Variation; Humans; Inheritance Patterns; Male; Models, Genetic; Phenotype; Propylthiouracil; Quinine; Sensitivity and Specificity; Siblings; Sucrose; Taste; Twins, Dizygotic; Twins, Monozygotic	2006
A complex relationship among chemical concentration, detection threshold, and suprathreshold intensity of bitter compounds. Chemical senses, 2007, Volume: 32, Issue:3 Topics: Adult; Caffeine; Dose-Response Relationship, Drug; Female; Humans; Male; Propylthiouracil; Quinine; Taste Threshold	2007
"A spoonful of sugar helps the medicine go down": bitter masking by sucrose among children and adults. Chemical senses, 2015, Volume: 40, Issue:1 Topics: Adult; Caffeine; Child; Child, Preschool; Female; Genotype; Heterozygote; Humans; Male; Propylthiouracil; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Sucrose; Taste Threshold; Urea	2015
The impact of individual variations in taste sensitivity on coffee perceptions and preferences. Physiology & behavior, 2015, Volume: 138 Topics: Adult; Caffeine; Coffee; Dietary Sucrose; Female; Food Preferences; Humans; Hydrochloric Acid; Male; Middle Aged; Propylthiouracil; Psychophysics; Quinine; Taste Perception; Taste Threshold; Tongue; Young Adult	2015
Dose-Dependent Effects of L-Arginine on PROP Bitterness Intensity and Latency and Characteristics of the Chemical Interaction between PROP and L-Arginine. PloS one, 2015, Volume: 10, Issue:6 Topics: Adult; Arginine; Caffeine; Carbonic Anhydrases; Dose-Response Relationship, Drug; Female; Food Preferences; Genotype; Humans; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Male; Phenotype; Propylthiouracil; Receptors, G-Protein-Coupled; Saliva; Solubility; Taste; Taste Perception; Young Adult	2015
Odor-Cued Bitter Taste Avoidance. Chemical senses, 2018, 04-23, Volume: 43, Issue:4 Topics: Animals; Aversive Agents; Avoidance Learning; Caffeine; Cues; Female; Mice; Olfactory Bulb; Propylthiouracil; Quaternary Ammonium Compounds; Quinine; Smell; Sucrose; Taste	2018
Associations between brain structure and perceived intensity of sweet and bitter tastes. Behavioural brain research, 2019, 05-02, Volume: 363 Topics: Adult; Australia; Aversive Agents; Brain; Caffeine; Connectome; Female; Humans; Male; Propylthiouracil; Quinine; Sucrose; Sweetening Agents; Taste; Taste Perception	2019