caffeine has been researched along with orphenadrine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (51.61) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.23) | 29.6817 |
| 2010's | 8 (25.81) | 24.3611 |
| 2020's | 6 (19.35) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Sen, S; Sinha, N | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gundersen, R; Høivik, HO; Osmundsen, K | 1 |
| Backe-Hansen, K; Skinnemoen, BE; Smit, A | 1 |
| Nathan, LA | 1 |
| Batterman, RC | 2 |
| Frascá, ID | 1 |
| Albertoni, WM; Fiori, EF; Frascá, ID; Frascá, JA; Pires, OS | 1 |
| McClure, DA | 1 |
| Dinan, B; Jick, H; Muench, H; Slone, D | 1 |
| Bianchine, JR; Goldlust, MB; Harrison, LI; Kehe, CR; Kvam, DC | 1 |
| Guay, DR; Meatherall, RC | 1 |
| CASS, LJ; FREDERIK, WS | 2 |
| BLUMENTHAL, LS; FUCHS, M | 1 |
| GOLDSTEIN, L; MURPHREE, HB; PFEIFFER, CC; SUGERMAN, AA | 1 |
| Darwish, K; El-Sadek, M; Mostafa, S; Salama, I | 1 |
| Abdelrahman, MM | 1 |
| Farhoudian, A; Fekri, M; Movaghar, AR; Rahimzadeh, S; Sadeghi, M; Sefatian, S; Vishteh, HR | 1 |
| Boltia, SA; Elzanfaly, ES; Soudi, AT; Zaazaa, HE | 2 |
| El-Adl, SM; Mattar, AA; Sebaiy, MM | 1 |
| Correia, AT; de Oliveira, TMN; Guimarães, LL; Pisetta, AM; Roveri, V | 1 |
| Correia, AT; Guimarães, LL; Roveri, V; Toma, W | 1 |
1 review(s) available for caffeine and orphenadrine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
5 trial(s) available for caffeine and orphenadrine
| Article | Year |
|---|---|
[Combined analgesics in myalgia of the neck. A double-blind comparison of paracetamol and orphenadrine (Norgesic) and paracetamol and codeine (Paralgin forte) in general practice].
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Muscles; Neck Muscles; Orphenadrine; Pain | 1986 |
Methodology of analgesic evaluation: experience with orphenadrine citrate compound.
Topics: Adult; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Orphenadrine; Phenacetin | 1965 |
Norgesic.
Topics: Aspirin; Caffeine; Clinical Trials as Topic; Humans; Orphenadrine; Phenacetin | 1965 |
Methodology of analgesic-muscle relaxant evaluation. Experience with orphenadrine citrate compound.
Topics: Adult; Aspirin; Caffeine; Clinical Trials as Topic; Female; Humans; Male; Muscles; Orphenadrine; Pain; Phenacetin | 1965 |
Evaluation of drug efficacy by a preference technic.
Topics: Arthritis, Rheumatoid; Aspirin; Caffeine; Dexamethasone; Dextropropoxyphene; Humans; Hypnotics and Sedatives; Orphenadrine; Phenacetin; Secobarbital | 1966 |
25 other study(ies) available for caffeine and orphenadrine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
On the Nordic Pharmacopoeia limit test for heavy metals. Heating with anhydrous sodium sulphate as a source of error.
Topics: Cadmium; Caffeine; Chlorine; Copper; Hot Temperature; Iron; Lead; Metals; Methods; Norway; Orphenadrine; Pharmacopoeias as Topic; Silicon Dioxide; Sodium; Spectrum Analysis; Sulfates | 1974 |
Dysmenorrhea and pre-menstrual tension in adolescents.
Topics: Adolescent; Aspirin; Caffeine; Dysmenorrhea; Female; Humans; Orphenadrine; Phenacetin; Premenstrual Syndrome | 1967 |
[New muscle relaxant analgesic in orthopedics and traumatology. Preliminary note].
Topics: Adolescent; Adult; Aged; Caffeine; Female; Humans; Male; Middle Aged; Muscular Diseases; Orphenadrine; Pyrazoles; Sulfonic Acids; Wounds and Injuries | 1970 |
[New muscle relaxant analgesic in orthopedics and traumatology (final evaluation of 100 treated cases)].
Topics: Adolescent; Adult; Analgesics; Caffeine; Female; Humans; Male; Middle Aged; Muscle Contraction; Neuromuscular Depolarizing Agents; Orphenadrine; Orthopedics; Pyrazoles; Sulfonic Acids; Wounds and Injuries | 1970 |
The poteniation of the analgesic action of APC by orphenadrine citrate.
Topics: Animals; Aspirin; Caffeine; Drug Synergism; Electric Stimulation; Mice; Orphenadrine; Phenacetin | 1965 |
Salicylic acid plasma levels following multiple doses of Norgesic Forte and aspirin.
Topics: Adult; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Kinetics; Male; Orphenadrine; Salicylates; Salicylic Acid | 1983 |
Isothermal gas chromatographic analysis of diphenhydramine after direct injection onto a fused-silica capillary column.
Topics: Caffeine; Chromatography, Gas; Diphenhydramine; Humans; Orphenadrine; Time Factors | 1984 |
AN EVALUATION OF ORPHENADRINE CITRATE IN COMBINATION WITH APC AS AN ANALGESIC.
Topics: Analgesics; Aspirin; Biomedical Research; Caffeine; Humans; Orphenadrine; Pharmacology; Phenacetin; Placebos | 1964 |
THE EVOLUTION OF A NEW ANALGESIC THROUGH CLINICAL STUDIES: A COMPARATIVE CLINICAL INVESTIGATION.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Biomedical Research; Caffeine; Codeine; Orphenadrine; Pharmacology; Phenacetin; Placebos; Toxicology | 1964 |
ANALGESIC COMBINATION IN HEADACHE.
Topics: Analgesics; Arthritis; Aspirin; Back Pain; Caffeine; Cervical Vertebrae; Drug Therapy; Headache; Humans; Intervertebral Disc Displacement; Lumbosacral Region; Orphenadrine; Osteoarthritis; Phenacetin; Torticollis; Toxicology | 1965 |
TIME-SERIES, FREQUENCY ANALYSIS, AND ELECTROGENESIS OF THE EEGS OF NORMALS AND PSYCHOTICS BEFORE AND AFTER DRUGS.
Topics: Amphetamine; Antidepressive Agents; Barbiturates; Biomedical Research; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Deanol; Drug Therapy; Electroencephalography; Lysergic Acid Diethylamide; Meprobamate; Orphenadrine; Pentobarbital; Perphenazine; Pharmacology; Phenobarbital; Placebos; Schizophrenia; Statistics as Topic; Tranquilizing Agents | 1965 |
Validated stability-indicating reversed-phase-HPLC method for simultaneous determination of orphenadrine citrate, caffeine and aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Limit of Detection; Muscarinic Antagonists; Orphenadrine | 2012 |
Selective spectrophotometric methods for determination of ternary mixture with overlapping spectra: a comparative study.
Topics: Area Under Curve; Aspirin; Caffeine; Chemistry, Pharmaceutical; Kinetics; Methanol; Orphenadrine; Reference Standards; Spectrophotometry | 2014 |
A tentative component analysis of Norjizak: A new abused drug in Iran.
Topics: Aspirin; Betamethasone; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Drug Combinations; Heroin; Iran; Orphenadrine; Substance-Related Disorders | 2015 |
Effect of Genetic Algorithm-Based Wavelength Selection as a Preprocessing Tool on Multivariate Simultaneous Determination of Paracetamol, Orphenadrine Citrate, and Caffeine in the Presence of p-Aminophenol Impurity.
Topics: Acetaminophen; Algorithms; Aminophenols; Caffeine; Calibration; Least-Squares Analysis; Orphenadrine | 2020 |
Different techniques for overlapped UV spectra resolution of some co-administered drugs with paracetamol in their combined pharmaceutical dosage forms.
Topics: Acetaminophen; Caffeine; Diclofenac; Linear Models; Models, Chemical; Orphenadrine; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2020 |
Development and Validation of Chromatographic Methods for Simultaneous Determination of Paracetamol, Orphenadrine Citrate and Caffeine in Presence of P-aminophenol; Quantification of P-aminophenol Nephrotoxic Impurity Using LC-MS/MS.
Topics: Acetaminophen; Aminophenols; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Densitometry; Drug Contamination; Excipients; Orphenadrine; Tablets; Tandem Mass Spectrometry | 2020 |
Orphengesic Forte - an old analgesic combination returns.
Topics: Analgesics; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Drug Interactions; Humans; Musculoskeletal Pain; Orphenadrine | 2020 |
First report on the occurrence of pharmaceuticals and cocaine in the coastal waters of Santa Catarina, Brazil, and its related ecological risk assessment.
Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Cosmetics; Diclofenac; Ecosystem; Environmental Monitoring; Humans; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Sewage; Solid Waste; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical | 2022 |
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil.
Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2022 |