caffeine and norclozapine

caffeine has been researched along with norclozapine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sen, S; Sinha, N1
de Leon, J; Odom-White, A1
Benítez, J; Carrillo, JA; Herraiz, AG; Ramos, SI1
Afra, P; Albers, LJ; Collins, EJ; Kalow, W; Kennedy, JL; Ozdemir, V; Posner, P; Reist, C; Roy, R; Tang, BK; Walkes, W1
Ansermot, N; Baumann, P; Crettol, S; Eap, CB; Harenberg, S; Jaquenoud Sirot, E; Knezevic, B; Morena, GP; Oneda, B1

Trials

2 trial(s) available for caffeine and norclozapine

ArticleYear
CYP1A2 activity as measured by a caffeine test predicts clozapine and active metabolite steady-state concentrationin patients with schizophrenia.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:4

    Topics: Adult; Aged; Antipsychotic Agents; Caffeine; Clozapine; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Psychotic Disorders; Reference Values; Schizophrenia; Smoking

2001
ABCB1 and cytochrome P450 polymorphisms: clinical pharmacogenetics of clozapine.
    Journal of clinical psychopharmacology, 2009, Volume: 29, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Fluvoxamine; Genotype; Humans; Male; Midazolam; Middle Aged; Phenotype; Polymorphism, Genetic; Substrate Specificity; Switzerland; Young Adult

2009

Other Studies

3 other study(ies) available for caffeine and norclozapine

ArticleYear
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Clozapine levels and caffeine.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:4

    Topics: Adult; Caffeine; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Humans; Mixed Function Oxygenases; Oxidoreductases; Psychotic Disorders

1996
Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patients.
    Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:4

    Topics: Adult; Antipsychotic Agents; Biological Availability; Biotransformation; Caffeine; Chromatography, High Pressure Liquid; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Substance Withdrawal Syndrome

1998