caffeine has been researched along with nicardipine in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.70) | 18.7374 |
| 1990's | 13 (35.14) | 18.2507 |
| 2000's | 14 (37.84) | 29.6817 |
| 2010's | 8 (21.62) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
| Somasundaram, B; Tregear, RT; Trentham, DR | 1 |
| Chang, CC; Hong, SJ; Huang, CY | 1 |
| Hatae, J; Kawata, H | 1 |
| Fujino, M; Sato, Y | 1 |
| Chapunoff, D; Herman, CA; Romero, MA; Schulmeister, K; Skarda, S; Torres, OA | 1 |
| Ogihara, M | 1 |
| Gerthoffer, WT; Publicover, NG; Sanders, KM; Sato, K | 1 |
| Hata, S; Ishii, K; Ishiro, H; Nakayama, K; Tanaka, Y | 1 |
| Advenier, C; Candenas, ML; Martin, JD; Moreau, J; Naline, E; Norte, M; Palette, C; Pays, M | 1 |
| Itoh, T; Kanmura, Y; Ohashi, M; Shiraishi, Y; Yamaguchi, S; Yoshimura, N | 1 |
| Hiraoka, M; Kawano, S; Kuruma, A | 1 |
| Thayer, SA; Usachev, YM | 1 |
| Guan, Z; Saqr, HE; Stokes, BT; Yates, AJ | 1 |
| Cameron, JS; Coyne, MD; Gwathmey, JK; Kim, CS | 1 |
| Nobe, H; Nobe, K; Obara, K; Paul, RJ | 1 |
| Nishi, K; Tokutomi, N; Tokutomi, Y | 1 |
| Jin, NG; Li, L; Li, Y; Li, ZL; Piao, L; Xu, WX | 1 |
| Fujita, A; Hata, F; Hirayama, N; Kitayama, M; Sumiyoshi, M; Takeuchi, T | 1 |
| Hong, SJ; Liang, HC; Shen, CJ | 1 |
| Cho, MC; Choi, MY; Choi, W; Hwang, KK; Kim, KW; Kim, YC; Lee, SJ; Lim, SW; Park, JK; Sim, JH | 1 |
| Fleming, NW; Hennig, GW; Keef, KD; Lee, HT; Sanders, KM; Smith, TK; Spencer, NJ; Ward, SM | 1 |
| Hashitani, H; Suzuki, H | 1 |
| Callison, CR; Kumar, AB; Miller, M | 1 |
| Lopatin, AN; Moench, I | 1 |
2 review(s) available for caffeine and nicardipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
35 other study(ies) available for caffeine and nicardipine
| Article | Year |
|---|---|
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
GTP gamma S causes contraction of skinned frog skeletal muscle via the DHP-sensitive Ca2+ channels of sealed T-tubules.
Topics: Animals; Binding Sites; Binding, Competitive; Caffeine; Calcium Channels; Dihydropyridines; Egtazic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Microtubules; Muscle Contraction; Nicardipine; Pertussis Toxin; Photolysis; Rana pipiens; Rana temporaria; Virulence Factors, Bordetella | 1991 |
Organic calcium channel antagonists provoke acetylcholine receptor autodesensitization on train stimulation of motor nerve.
Topics: Animals; Bungarotoxins; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Diaphragm; Egtazic Acid; Electric Stimulation; Electrophysiology; Mice; Motor Endplate; Muscle Contraction; Neostigmine; Nicardipine; Phrenic Nerve; Receptors, Cholinergic; Theophylline | 1990 |
Dependence of contractile responses by some calcium antagonists on external calcium in the skeletal muscle.
Topics: Animals; Caffeine; Calcium; Membrane Potentials; Muscle Contraction; Muscles; Nicardipine; Ranidae; Verapamil | 1990 |
Inhibition of excitation-contraction coupling by a Ca channel blocker nicardipine at low temperature in frog twitch fibers.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cold Temperature; Electrophysiology; Muscle Contraction; Nicardipine; Potassium; Ranidae | 1987 |
Leukotriene C4-stimulated contractions in bullfrog lung are affected by cold acclimation and calcium antagonists.
Topics: Acclimatization; Animals; Caffeine; Calcium Channel Blockers; Calcium-Transporting ATPases; Cold Temperature; Contracture; Egtazic Acid; Eicosapentaenoic Acid; Female; Hot Temperature; Leukotriene C4; Lung; Male; Nicardipine; Nifedipine; Nitrendipine; Rana catesbeiana; SRS-A; Terpenes; Thapsigargin; Verapamil | 1995 |
Nifedipine and nicardipine potentiate glucagon-stimulated glycogenolysis in primary cultures of rat hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Glycogen; Liver; Male; Nicardipine; Nifedipine; Papaverine; Rats; Rats, Wistar | 1993 |
Sources of calcium utilized in cholinergic responses in canine colonic smooth muscle.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Colon; Dogs; Female; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Ryanodine | 1994 |
Stretching releases Ca2+ from intracellular storage sites in canine cerebral arteries.
Topics: Animals; Basilar Artery; Caffeine; Calcium; Calcium Channel Blockers; Carbamates; Cholera Toxin; Dogs; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Phenylcarbamates; Ryanodine; Temperature; Type C Phospholipases; Virulence Factors, Bordetella | 1994 |
Effects of okadaic acid on the human isolated bronchus.
Topics: Acetylcholine; Bronchi; Cadmium; Cadmium Compounds; Caffeine; Dose-Response Relationship, Drug; Ethers, Cyclic; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Nicardipine; Okadaic Acid; Papaverine; Phosphatidylinositols; Potassium Chloride; Sulfates; Vasoconstrictor Agents | 1994 |
Possible mechanisms underlying the midazolam-induced relaxation of the noradrenaline-contraction in rabbit mesenteric resistance artery.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Midazolam; Muscle Contraction; Muscle Relaxation; Nicardipine; Norepinephrine; Potassium; Rabbits; Vascular Resistance; Vasodilator Agents | 1997 |
Activation of Ca2+-sensitive Cl- current by reverse mode Na+/Ca2+ exchange in rabbit ventricular myocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Caffeine; Calcium; Chloride Channels; Electric Conductivity; Female; Heart; Heart Ventricles; Kinetics; Male; Nicardipine; Patch-Clamp Techniques; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Sodium; Sodium-Calcium Exchanger; Thapsigargin; Ventricular Function | 1998 |
Ca2+ influx in resting rat sensory neurones that regulates and is regulated by ryanodine-sensitive Ca2+ stores.
Topics: Action Potentials; Animals; Animals, Newborn; Biological Transport; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Ganglia, Spinal; Membrane Potentials; Neurons, Afferent; Nicardipine; Nimodipine; Patch-Clamp Techniques; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Ryanodine; Ryanodine Receptor Calcium Release Channel | 1999 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Elapid Venoms; Endoplasmic Reticulum; Enzyme Inhibitors; Flufenamic Acid; Glioma; Humans; Imidazoles; Ion Transport; Masoprocol; Neoplasm Proteins; Nicardipine; Nimodipine; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Peptides; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Ryanodine; Thapsigargin; Tumor Cells, Cultured; Verapamil | 1999 |
Effects of temperature and calcium availability on ventricular myocardium from rainbow trout.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adrenergic beta-Agonists; Animals; Body Temperature; Cadmium; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System Stimulants; Cold Temperature; Heart Ventricles; Isometric Contraction; Isoproterenol; Myocardial Contraction; Myocardium; Nicardipine; Oncorhynchus mykiss; Oxygen Consumption; Patch-Clamp Techniques; Ryanodine; Sarcolemma; Ventricular Function | 2000 |
Preferential role of intracellular Ca2+ stores in regulation of isometric force in NIH 3T3 fibroblast fibres.
Topics: 3T3 Cells; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cattle; Drug Synergism; Endoplasmic Reticulum; Enzyme Inhibitors; Estrenes; Fibroblasts; Indoles; Intracellular Membranes; Mice; Nicardipine; Potassium Chloride; Pyrrolidinones; Ryanodine; Thapsigargin; Type C Phospholipases | 2000 |
The properties of ryanodine-sensitive Ca(2+) release in mouse gastric smooth muscle cells.
Topics: Animals; Bucladesine; Caffeine; Calcium; Carbachol; Cells, Cultured; Dose-Response Relationship, Drug; Electric Conductivity; Fura-2; Gastric Mucosa; In Vitro Techniques; Ion Channel Gating; Isometric Contraction; Large-Conductance Calcium-Activated Potassium Channels; Mice; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Nicardipine; Potassium; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Chloride; Ryanodine; Stomach; Tetraethylammonium | 2001 |
The involvement of calcium mobilization in the calcium-activated potassium currents activated by hyposmotic swelling in gastric antral circular myocytes of the guinea-pig.
Topics: Animals; Caffeine; Calcium Channel Blockers; Central Nervous System Stimulants; Female; Gadolinium; Guinea Pigs; Male; Muscle, Smooth; Myocardium; Nicardipine; Osmotic Pressure; Patch-Clamp Techniques; Potassium Channels; Pyloric Antrum; Ryanodine; Stomach | 2001 |
Origin of Ca2+ necessary for carbachol-induced contraction in longitudinal muscle of the proximal colon of rats.
Topics: Aminobenzoates; Animals; Caffeine; Calcium; Calcium Channel Blockers; Carbachol; Chlorobenzoates; Cinnamates; Colon; Enzyme Inhibitors; Gastrointestinal Motility; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; ortho-Aminobenzoates; Parasympathomimetics; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Thapsigargin | 2001 |
Alteration of cyclopiazonic acid-mediated contracture of mouse diaphragm after denervation.
Topics: Action Potentials; Animals; Biological Assay; Boron Compounds; Caffeine; Cromakalim; Crotalid Venoms; Diaphragm; Electric Stimulation; Estrenes; Female; Glyburide; Indoles; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle Denervation; Nicardipine; Phrenic Nerve; Pyrrolidinones; Sarcoplasmic Reticulum | 2005 |
Regulation of membrane excitability by intracellular pH (pHi) changers through Ca2+-activated K+ current (BK channel) in single smooth muscle cells from rabbit basilar artery.
Topics: Ammonium Chloride; Animals; Basilar Artery; Caffeine; Calcium; Calcium Channel Blockers; Calcium Signaling; Cytoplasm; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Hydrogen-Ion Concentration; Isometric Contraction; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Myocytes, Smooth Muscle; Nicardipine; Rabbits; Sodium Acetate; Tetraethylammonium | 2007 |
The mechanism and spread of pacemaker activity through myenteric interstitial cells of Cajal in human small intestine.
Topics: Adult; Biological Clocks; Caffeine; Calcium; Calcium Channel Blockers; Central Nervous System Stimulants; Electrophysiology; Female; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate Receptors; Intestinal Mucosa; Jejunum; Male; Middle Aged; Myenteric Plexus; Myocytes, Smooth Muscle; Nicardipine | 2007 |
Properties of spontaneous Ca2+ transients recorded from interstitial cells of Cajal-like cells of the rabbit urethra in situ.
Topics: Adrenergic alpha-Agonists; Animals; Boron Compounds; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Calcium-Transporting ATPases; Enzyme Inhibitors; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Male; Membrane Potentials; Molsidomine; Muscle Contraction; Myocytes, Smooth Muscle; Nicardipine; Nitric Oxide; Nitric Oxide Donors; Phenylephrine; Rabbits; Receptors, Adrenergic, alpha; Ryanodine; Ryanodine Receptor Calcium Release Channel; Time Factors; Urethra | 2007 |
Refractory caffeine and ergot-induced cervico-cerebral vasospasm and stroke treated with combined medical and endovascular approach.
Topics: Adult; Caffeine; Cerebral Angiography; Dihydroergotamine; Drug Therapy, Combination; Female; Humans; Magnetic Resonance Angiography; Migraine Disorders; Nicardipine; Phosphodiesterase Inhibitors; Stents; Stroke; Vasoconstrictor Agents; Vasodilator Agents; Vasospasm, Intracranial | 2012 |
Ca(2+) homeostasis in sealed t-tubules of mouse ventricular myocytes.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Cytoplasm; Dinitrophenols; Heart Ventricles; Homeostasis; Ion Transport; Membrane Potentials; Mice; Myocytes, Cardiac; Nicardipine; Potassium; Sarcolemma; Uncoupling Agents | 2014 |