Compounds > caffeine

caffeine and n-acetyl-4-benzoquinoneimine

caffeine has been researched along with n-acetyl-4-benzoquinoneimine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kalhorn, TF; Lee, CA; Nelson, SD; Slattery, JT1
Jaw, S; Jeffery, EH1
Lee, CA; Lillibridge, JH; Nelson, SD; Slattery, JT1
Lee, CA; Manyike, PT; Nelson, SD; Slattery, JT; Thummel, KE1
Court, MH; Duan, SX; Evans, RM; Greenblatt, DJ; Hao, Q; Hunt, JA; Jeffery, EH; Lan, L; Schuetz, EG; Sinclair, JF; Sinclair, PR; Szakacs, JG; von Moltke, LL; Walton-Strong, BW; Wolf, KK; Wood, SG; Wrighton, SA; Yasuda, K1

Other Studies

5 other study(ies) available for caffeine and n-acetyl-4-benzoquinoneimine

ArticleYear
Effect of methylxanthines on acetaminophen hepatotoxicity in various induction states.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1

    Topics: Acetaminophen; Alanine Transaminase; Animals; Benzoquinones; Body Temperature; Caffeine; Glutathione; Imines; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Theobromine; Theophylline

1990
Interaction of caffeine with acetaminophen. 1. Correlation of the effect of caffeine on acetaminophen hepatotoxicity and acetaminophen bioactivation following treatment of mice with various cytochrome P450 inducing agents.
    Biochemical pharmacology, 1993, Aug-03, Volume: 46, Issue:3

    Topics: Acetaminophen; Acetone; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzoquinones; beta-Naphthoflavone; Biotransformation; Caffeine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Activation; Female; Imines; Isoenzymes; Kinetics; Liver Diseases; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital

1993
Effects of caffeine and theophylline on acetaminophen pharmacokinetics: P450 inhibition and activation.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzoquinones; Caffeine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Activation; Glutathione; Imines; Male; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Theophylline

1996
Mechanism of cytochrome P450 activation by caffeine and 7,8-benzoflavone in rat liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:10

    Topics: Animals; Benzoflavones; Benzoquinones; Caffeine; Cytochrome P-450 Enzyme System; Cytochromes b5; Electron Transport; Enzyme Activation; Imines; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Sprague-Dawley

1997
Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:12

    Topics: Acetaminophen; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoquinones; Biological Transport; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Glutathione; Hepatocytes; Imines; Intestinal Absorption; Liver; Mice; Mice, Inbred C57BL; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcription, Genetic

2005