caffeine and n(6)-cyclohexyladenosine

caffeine has been researched along with n(6)-cyclohexyladenosine in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (33.33)	18.7374
1990's	21 (53.85)	18.2507
2000's	5 (12.82)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jacobson, KA; van Galen, PJ; Williams, M	1
Browne, RG; Howard, HR; Koe, BK; Lebel, LA; Sarges, R; Seymour, PA	1
Daly, JW	1
Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U	1
Hara, T; Minematsu, N; Mizuki, Y; Obara, N; Ushijima, I; Yamada, M	1
Guillet, R; Kellogg, CK	1
Holtzman, SG; Mante, S; Minneman, KP	1
Brownstone, RM; Geiger, JD; Lesiuk, HJ; Peeling, J; Rydzy, M; Saunders, JK; Sutherland, GR	1
Seale, TW; Sekar, KC; Sheldon, RE; Toubas, PL	1
Durcan, MJ; Morgan, PF	1
Clark, M; Post, RM	1
Sosnowski, M; Stevens, CW; Yaksh, TL	1
Abla, KA; Carney, JM; Daly, JW; Seale, TW; Shamim, MT	1
Coffin, VL; Spealman, RD	1
Buckholtz, NS; Middaugh, LD	1
Marangos, PJ; Patel, J; Post, RM; Weiss, SR	1
Anderson, SM; Daly, JW; Padgett, W; Weir, RL	1
Caldwell, P; Emmett-Oglesby, MW; Spencer, DG	1
Plagemann, PG; Wohlhueter, RM	1
Boulenger, JP; Marangos, PJ; Patel, J	1
Boulenger, JP; Marangos, PJ; Parma, AM; Patel, J; Post, RM	1
Butts-Lamb, P; Daly, JW; Padgett, W	1
Schiffmann, SN; Vanderhaeghen, JJ	1
Etzel, BA; Guillet, R	1
Shafaghi, B; Zarrindast, MR	1
Fisher, CE; Hughes, RN	1
Poon, A; Sawynok, J	1
Shaban, M; Smith, RA; Stone, TW	1
Jen, SC; Rovainen, CM	1
Fredholm, BB; Georgiev, V; Johansson, B; Lindström, K	1
Frobenius, W; Geis, U; Hipp, J; Müller, CE; Pawłowski, M; Sandoval-Ramírez, J; Schobert, U; Suzuki, F	1
Akimoto, T; Mashimoto, S; Suetsugi, M; Ushijima, I; Watanabe, K; Yamada, M	1
Fredholm, BB; Lindström, K	1
Aguirre-Bañuelos, P; Castañeda-Hernández, G; Granados-Soto, V; López-Muñoz, FJ; Pérez-Urizar, J	1
Antle, MC; Mistlberger, RE; Steen, NM	1
Berrino, L; Capuano, A; De Novellis, V; Filippelli, A; Mazzeo, F; Rossi, F; Stella, L; Vitelli, MR	1
Gu, R; Li, W; Shan, H; Wang, J; Wang, WH; Xu, Y; Yang, B; Zhang, Y	1
Binfaré, RW; Budni, J; Lobato, KR; Rodrigues, AL; Rosa, AO; Santos, AR	1
Burbiel, CE; Knittel, J; Müller, CE; Töpfer, M; Verspohl, EJ	1

Reviews

2 review(s) available for caffeine and n(6)-cyclohexyladenosine

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992
Adenosine receptors: targets for future drugs. Journal of medicinal chemistry, 1982, Volume: 25, Issue:3 Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines	1982

Other Studies

37 other study(ies) available for caffeine and n(6)-cyclohexyladenosine

Article	Year
4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants. Journal of medicinal chemistry, 1990, Volume: 33, Issue:8 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Cats; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Corpus Striatum; Male; Molecular Structure; Motor Activity; Purinergic Antagonists; Quinoxalines; Rats; Receptors, Purinergic; Sleep; Structure-Activity Relationship; Triazoles	1990
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium	1999
Effects of lithium and purinergic compounds on the behavioral and physiological aspects of restraint stress in rats. Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3 Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Defecation; Injections, Intraperitoneal; Injections, Intraventricular; Lithium; Male; Motor Activity; Purines; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer; Stress, Psychological	1992
Neonatal caffeine exposure alters developmental sensitivity to adenosine receptor ligands. Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:4 Topics: Adenosine; Age Factors; Animals; Animals, Newborn; Brain; Caffeine; Kinetics; Ligands; Motor Activity; Phenylisopropyladenosine; Rats; Receptors, Purinergic	1991
Role of adenosine receptors in caffeine tolerance. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Administration, Oral; Animals; Binding Sites; Brain; Caffeine; Cyclic AMP; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Time Factors; Tritium; Xanthines	1991
The effects of caffeine on ischemic neuronal injury as determined by magnetic resonance imaging and histopathology. Neuroscience, 1991, Volume: 42, Issue:1 Topics: Adenosine; Animals; Blood Pressure; Brain Ischemia; Caffeine; Cerebral Cortex; Corpus Striatum; Hippocampus; Histocytochemistry; Magnetic Resonance Imaging; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Purinergic	1991
Fetal and newborn lambs differ in their cardiopulmonary responsiveness to adenosine agonists. Developmental pharmacology and therapeutics, 1990, Volume: 15, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Blood Pressure; Bradycardia; Caffeine; Female; Heart; Heart Rate, Fetal; Hydrogen-Ion Concentration; Phenylisopropyladenosine; Pregnancy; Pulmonary Gas Exchange; Respiration; Sheep; Vasodilator Agents	1990
Caffeine-induced seizures: apparent proconvulsant action of N-ethyl carboxamidoadenosine (NECA). Life sciences, 1990, Volume: 47, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Caffeine; Cerebral Ventricles; Dose-Response Relationship, Drug; Male; Mice; Premedication; Receptors, Purinergic; Regression Analysis; Seizures	1990
Carbamazepine, but not caffeine, is highly selective for adenosine A1 binding sites. European journal of pharmacology, 1989, May-19, Volume: 164, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Carbamazepine; Cerebellum; Corpus Striatum; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic	1989
Assessment of the role of A1/A2 adenosine receptors mediating the purine antinociception, motor and autonomic function in the rat spinal cord. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autonomic Nervous System; Blood Pressure; Caffeine; Male; Movement; Pain; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Spinal Cord; Urinary Bladder	1989
3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs. Life sciences, 1988, Volume: 43, Issue:21 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Body Temperature; Caffeine; Male; Mice; Mice, Inbred DBA; Motor Activity; Reference Values; Theobromine; Theophylline	1988
Behavioral and cardiovascular effects of analogs of adenosine in cynomolgus monkeys. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1 Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Blood Pressure; Caffeine; Cardiovascular System; Clonidine; Cocaine; Dextroamphetamine; Heart Rate; Isomerism; Macaca fascicularis; Male; Phenylisopropyladenosine	1987
Effects of caffeine and L-phenylisopropyladenosine on locomotor activity of mice. Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:2 Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Phenylisopropyladenosine; Time Factors; Tritium	1987
Adenosine antagonists. Lack of effect on the inhibition of kindled seizures in rats by carbamazepine. Neuropharmacology, 1985, Volume: 24, Issue:7 Topics: Adenosine; Animals; Caffeine; Carbamazepine; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Seizures; Theophylline	1985
Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system. Epilepsia, 1984, Volume: 25, Issue:4 Topics: Adenosine; Animals; Anticonvulsants; Brain; Caffeine; Carbamazepine; Cerebellum; Cerebral Cortex; Cyclic AMP; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline	1984
Tolerance to N6-(L-phenylisopropyl) adenosine. Contribution of behavioral mechanisms and cross-tolerance profile. Neuropharmacology, 1984, Volume: 23, Issue:6 Topics: Adenosine; Animals; Behavior, Animal; Caffeine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic	1984
Inhibition of the transport of adenosine, other nucleosides and hypoxanthine in novikoff rat hepatoma cells by methylxanthines, papaverine, N6-cyclohexyladenosine and N6-phenylisopropyladenosine. Biochemical pharmacology, 1984, Jun-01, Volume: 33, Issue:11 Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Biological Transport, Active; Caffeine; Cell Line; Hypoxanthine; Hypoxanthines; Liver Neoplasms, Experimental; Papaverine; Phenylisopropyladenosine; Rats; Theophylline; Uridine; Xanthines	1984
Effects of caffeine and theophylline on adenosine and benzodiazepine receptors in human brain. Neuroscience letters, 1982, May-28, Volume: 30, Issue:2 Topics: Adenosine; Binding, Competitive; Brain; Caffeine; Diazepam; Humans; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Receptors, Purinergic; Theophylline; Xanthines	1982
Chronic caffeine consumption increases the number of brain adenosine receptors. Life sciences, 1983, Mar-07, Volume: 32, Issue:10 Topics: Adenosine; Animals; Brain; Caffeine; Diazepam; Diet; Mice; Receptors, Cell Surface; Receptors, Purinergic; Xanthines	1983
Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines. Cellular and molecular neurobiology, 1983, Volume: 3, Issue:1 Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Brain; Caffeine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theobromine; Theophylline; Xanthines	1983
Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Corpus Striatum; Enkephalins; Gene Expression Regulation; Globus Pallidus; Neurons; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Purinergic; Substance P; Substantia Nigra	1993
Effects of neonatal exposure to caffeine on adenosine A1 receptor ontogeny using autoradiography. Brain research. Developmental brain research, 1994, Oct-14, Volume: 82, Issue:1-2 Topics: Adenosine; Administration, Oral; Aging; Animals; Animals, Newborn; Autoradiography; Brain; Caffeine; Cerebellum; Female; Hippocampus; Humans; Infant, Newborn; Infant, Premature; Male; Neurons; Organ Specificity; Pyramidal Cells; Rats; Receptors, Purinergic P1; Thalamus; Tritium	1994
Effects of adenosine receptor agonists and antagonists on acquisition of passive avoidance learning. European journal of pharmacology, 1994, May-02, Volume: 256, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Avoidance Learning; Caffeine; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Theophylline; Vasodilator Agents	1994
Effects of diazepam and cyclohexyladenosine on open-field behavior in rats perinatally exposed to caffeine. Life sciences, 1996, Volume: 58, Issue:8 Topics: Adenosine; Animals; Caffeine; Diazepam; Eliminative Behavior, Animal; Emotions; Female; Grooming; Locomotion; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Sex Characteristics	1996
Antinociception by adenosine analogs and an adenosine kinase inhibitor: dependence on formalin concentration. European journal of pharmacology, 1995, Nov-14, Volume: 286, Issue:2 Topics: Adenosine; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Caffeine; Deoxyadenosines; Enzyme Inhibitors; Formaldehyde; Male; Pentostatin; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1	1995
Purine suppression of proliferation of Sertoli-like TM4 cells in culture. Cell proliferation, 1995, Volume: 28, Issue:12 Topics: Adenosine; Animals; Caffeine; Cell Division; Cells, Cultured; Male; Mice; Purinergic P1 Receptor Antagonists; Purines; Receptors, Purinergic P1; Sertoli Cells; Theobromine; Theophylline	1995
An adenosine agonist increases blood flow and density of capillary branches in the optic tectum of Xenopus laevis tadpoles. Microcirculation (New York, N.Y. : 1994), 1994, Volume: 1, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Capillaries; Microcirculation; Microscopy, Video; Neovascularization, Physiologic; Nitroglycerin; Regional Blood Flow; Superior Colliculi; Theophylline; Time Factors; Vasodilator Agents; Xenopus laevis	1994
A1 and A2A adenosine receptors and A1 mRNA in mouse brain: effect of long-term caffeine treatment. Brain research, 1997, Jul-11, Volume: 762, Issue:1-2 Topics: Adenosine; Animals; Antihypertensive Agents; Autoradiography; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; In Situ Hybridization; Male; Mice; Mice, Inbred Strains; Phenethylamines; Radioligand Assay; Receptors, Purinergic P1; RNA, Messenger; Time Factors; Tritium; Xanthines	1997
Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonists. Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26 Topics: Adenosine; Animals; Binding, Competitive; Brain; Caffeine; Molecular Structure; Phenethylamines; Protein Binding; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Theobromine; Xanthines	1997
Stress-dependent antinociceptive effects of carbamazepine: a study in stressed and nonstressed rats. Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:1 Topics: Adenosine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Caffeine; Carbamazepine; Cerebral Ventricles; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Male; Naloxone; Pain; Physical Stimulation; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Time Factors	1998
Autoradiographic comparison of the potency of several structurally unrelated adenosine receptor antagonists at adenosine A1 and A(2A) receptors. European journal of pharmacology, 1999, Sep-10, Volume: 380, Issue:2-3 Topics: Adenosine; Animals; Autoradiography; Binding, Competitive; Brain; Caffeine; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Pyrazines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Tritium; Xanthines	1999
Activation of adenosine A1 receptors facilitates the analgesic effect of ketorolac and ketorolac-caffeine combinations in the rat. Proceedings of the Western Pharmacology Society, 1999, Volume: 42 Topics: Adenosine; Analgesics, Non-Narcotic; Animals; Area Under Curve; Caffeine; Central Nervous System Stimulants; Drug Synergism; Female; Ketorolac; Pain Measurement; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar	1999
Adenosine and caffeine modulate circadian rhythms in the Syrian hamster. Neuroreport, 2001, Sep-17, Volume: 12, Issue:13 Topics: Adenosine; Animals; Caffeine; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Mesocricetus; Motor Activity; Neurons; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sleep; Sleep Deprivation; Suprachiasmatic Nucleus	2001
Interactive role of adenosine and dopamine in the opiate withdrawal syndrome. Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:2 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Chromatography, High Pressure Liquid; Dopamine; Injections, Subcutaneous; Male; Microdialysis; Morphine; Pyrimidines; Rats; Rats, Wistar; Receptors, Dopamine; Substance Withdrawal Syndrome; Triazoles	2003
Adenosine stimulates the basolateral 50 pS K channels in the thick ascending limb of the rat kidney. American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:1 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenylyl Cyclases; Algorithms; Animals; Bucladesine; Caffeine; Dose-Response Relationship, Drug; Enzyme Activation; Female; Kidney; Male; Patch-Clamp Techniques; Phenethylamines; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Adenosine A2; Stimulation, Chemical; Xanthines	2007
Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test. Progress in neuro-psychopharmacology & biological psychiatry, 2008, May-15, Volume: 32, Issue:4 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Aniline Compounds; Animals; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Dipyridamole; Female; Male; Mice; Motor Activity; Nucleoside Transport Proteins; Receptor, Adenosine A1; Receptor, Adenosine A2A; Swimming; Triazines; Triazoles; Xanthines; Zinc	2008
Modulation of insulin release by adenosine A1 receptor agonists and antagonists in INS-1 cells: the possible contribution of 86Rb+ efflux and 45Ca2+ uptake. Cell biochemistry and function, 2008, Volume: 26, Issue:8 Topics: 3T3-L1 Cells; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Analgesics; Animals; Antineoplastic Agents; Caffeine; Calcium; Calcium Channels; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Insulin; Mice; Potassium Channels; Rats; Rats, Wistar; Receptor, Adenosine A1; Rubidium; Xanthines	2008