caffeine and methylphenidate

caffeine has been researched along with methylphenidate in 95 studies

Research

Studies (95)

Timeframe	Studies, this research(%)	All Research%
pre-1990	61 (64.21)	18.7374
1990's	3 (3.16)	18.2507
2000's	13 (13.68)	29.6817
2010's	14 (14.74)	24.3611
2020's	4 (4.21)	2.80

Authors

Authors	Studies
Butler, DE; L'Italien, YJ; Marriott, JG; Nordin, IC; Poschel, PH; Zweisler, L	1
Butler, DE; Marriott, JG; Poschel, BP	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Arnold, LE; Bhatara, V; Knopp, W; Smeltzer, DJ	1
Bartus, RT	1
Roussinov, K; Yonkov, D	1
Sansone, M	1
Arnold, LE; Christopher, J; Huestis, R; Smeltzer, DJ	1
Davey, J; Firestone, P; Goodman, JT; Peters, S	1
Garfinkel, BD; Sloman, L; Webster, CD	3
Greig, AM; Hughes, RN	1
Arnold, LE; Huestis, RD; Smeltzer, DJ	1
Gross, MD	1
Dawsey, WJ; Geyer, MA; Mandell, AJ	1
Isaac, W; Kallman, WM	1
Finn, IB; Holtzman, SG; Iuvone, PM	1
Asami, T; Ida, I; Kuribara, H; Machiyama, Y; Tadokoro, S	1
Beuthin, FC; Louis-Ferdinand, RT; Rosen, JB; Young, AM	1
Burgess, KE	1
Jones, RS; Olpe, HR; Steinmann, MW	1
Finn, IB; Holtzman, SG	1
Holloway, FA; Shull, RN	1
Baiguerra, G; Giraud, O; Valzelli, L	1
Holtzman, SG	1
Giurgea, C; Leemans, R; Mouravieff-Lesuisse, F	1
Winnie, AP	1
Machata, G	1
Saito, A; Shibata, M; Takagi, K; Watanabe, M	1
Busca, GP	1
Diversi, G; Gallizia, G	1
Kornetsky, C; Orzack, MH; Taylor, CL	1
DaVanzo, JP; Kang, LS; Kline, ES; Ward, JW; Watterson, JR	1
Fog, R	2
Chiba, S; Nagawa, Y; Yui, T	1
Carr, LA; Moore, KE	1
Ditzler, W; Plotnikoff, N; Will, F	1
Dandiya, PC; Gupta, BD; Gupta, ML	1
Allen, LE; Ferguson, HC; McKinney, GR	1
Klapper, JA; McColloch, MA	1
Kulkarni, AS	1
Estler, CJ	1
Schnackenberg, RC	1
Schulze, HA	1
Burgison, RM; Dietz, AJ	1
Iwasawa, Y; Takagi, K	1
Marriott, AS	1
Priyatkina, TN; Sytinskii, IA	1
Evans, AV; Plotnikoff, N	1
Nicholson, AN; Stone, BM	1
Matthies, H; Roussinov, K; Wetzel, W; Yonkov, D	1
Matsue, Y; Matsuoka, H; Okuma, T; Toyomura, K	1
Holloway, WR; Thor, DH	1
Carney, JM; Holloway, FA; Modrow, HE	1
Donev, N; Petkov, V	1
Biaggioni, I; Black, BK; Jordan, J; Norman, R; Robertson, D; Shannon, JR	1
Homsi, J; Nelson, KA; Walsh, D	1
Arneric, SP; Bain, JN; Buccafusco, JJ; Prendergast, MA; Smith, MA; Terry, AV	1
Hall, SS	1
LATRANYI, M; MECHNER, F	1
FITZLOFF, J; PLOTNIKOFF, NP	1
WHITE, RP	1
GROSSMANN, V; MRAZOVA, J; VESELY, C	1
GRANT, WM; PECZON, JD	1
CROMLEY, WH; EBY, RZ; FELLOWS, EJ; FOWLER, PJ; PAULS, JF; TEDESCHI, DH	1
RUDOLPH, AS; SEWELL, HH; WHITE, RP	1
Bizarro, L; Murtagh, C; Patel, S; Stolerman, IP	1
Pereira, RR; van de Wetering, BJ	1
Alisky, JM	1
Fernandes, D; Pamplona, FA; Pandolfo, P; Pires, VA; Prediger, RD; Takahashi, RN	1
Boeck, CR; Constantino, LC; Lima, FF; Marques, VB; Quevedo, J; Romano-Silva, MA; Rosa, DV; Valvassori, SS	1
Ali, M; Auger, RR; Morgenthaler, TI; Slocumb, NL	1
Elie, D; Gagnon, B; Gagnon, P; Giguère, A	1
Flood, DG; Gasior, M; Marino, MJ; Zuvich, E	1
Pamplona, FA; Pandolfo, P; Pires, VA; Prediger, RD; Takahashi, RN	1
Matsumoto, K; Murakami, Y; Ono, K; Ouchi, H	1
Dimpfel, W	1
Anagnostaras, SG; Sage, JR; Shuman, T; Wood, S	1
Fond, G; MacGregor, A; Micoulaud-Franchi, JA	1
Chinthapalli, K	1
Dance, A	1
Agricola, A; Balló, HE; Frank, B; Franke, AG; Gerdes, C; Gorbulev, S; Gränsmark, P; Lieb, K; Rommel, T; Ruckes, C; Schühle, K; Sebastian, A; Tüscher, O	1
Barcellos, LJG; de Alcantara Barcellos, HH; Fortuna, M; Freddo, N; Koakoski, G; Maffi, VC; Mozzato, MT; Pompermaier, A; Rossato-Grando, LG; Soares, SM; Varela, ACC	1
Bovy, L; Dresler, M; Kühn, S; Ohla, K; Repantis, D	1
Adam, LC; Dresler, M; Konrad, BN; Kühn, S; Repantis, D	1
Becker, M; Dresler, M; Kühn, S; Repantis, D	1

Reviews

6 review(s) available for caffeine and methylphenidate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
On stereotypy and catalepsy: studies on the effect of amphetamines and neuroleptics in rats. Acta neurologica Scandinavica. Supplementum, 1972, Volume: 50 Topics: Amphetamine; Animals; Basal Ganglia; Caffeine; Catalepsy; Cocaine; Compulsive Behavior; Corpus Striatum; Disease Models, Animal; Dopamine; Hippocampus; Humans; Lysergic Acid Diethylamide; Methamphetamine; Methylphenidate; Morphine; Norepinephrine; Pemoline; Phenmetrazine; Psychoses, Substance-Induced; Rats; Reserpine; Thalamus; Tranquilizing Agents	1972
Psychostimulants in supportive care. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2000, Volume: 8, Issue:5 Topics: Adult; Caffeine; Central Nervous System Stimulants; Child; Dextroamphetamine; Ephedrine; Humans; Mental Disorders; Methylphenidate; Neoplasms; Pemoline; Substance-Related Disorders	2000
SEDATIVES, STIMULANTS, AND INTRAOCULAR PRESSURE IN GLAUCOMA. Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 72 Topics: Anticonvulsants; Barbiturates; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Glaucoma; Hydantoins; Hypnotics and Sedatives; Intraocular Pressure; Meperidine; Mephenesin; Meprobamate; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pharmacology; Phenytoin; Primidone; Promethazine; Reserpine; Tonometry, Ocular; Tranquilizing Agents	1964
[Using psychostimulants in end-of-life patients with hypoactive delirium and cognitive disorders: A literature review]. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2010, Volume: 55, Issue:6 Topics: Aged; Caffeine; Central Nervous System Stimulants; Cognition Disorders; Confusion; Delirium; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Mental Status Schedule; Methylphenidate; Middle Aged; Palliative Care; Psychomotor Disorders; Randomized Controlled Trials as Topic; Terminal Care	2010
Psychostimulants and cognition: a continuum of behavioral and cognitive activation. Pharmacological reviews, 2014, Volume: 66, Issue:1 Topics: Animals; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cocaine; Cognition; Humans; Methamphetamine; Methylphenidate; Modafinil	2014

Trials

16 trial(s) available for caffeine and methylphenidate

Article	Year
A survey study of the use of electropupillogram in predicting response to psychostimulants. Psychopharmacology, 1978, Apr-28, Volume: 57, Issue:2 Topics: Adolescent; Caffeine; Central Nervous System Stimulants; Child; Child, Preschool; Dextroamphetamine; Humans; Hyperkinesis; Methylphenidate; Pupil; Time Factors	1978
Methylphenidate vs dextroamphetamine vs caffeine in minimal brain dysfunction: controlled comparison by placebo washout design with Bayes' analysis. Archives of general psychiatry, 1978, Volume: 35, Issue:4 Topics: Attention Deficit Disorder with Hyperactivity; Caffeine; Child; Child, Preschool; Clinical Trials as Topic; Dextroamphetamine; Dose-Response Relationship, Drug; Double-Blind Method; Factor Analysis, Statistical; Female; Humans; Hyperkinesis; Male; Methylphenidate	1978
Individual responses to methylphenidate and caffeine in children with minimal brain dysfunction. Canadian Medical Association journal, 1975, Oct-18, Volume: 113, Issue:8 Topics: Attention Deficit Disorder with Hyperactivity; Caffeine; Child; Citrates; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Humans; Male; Methylphenidate	1975
Methylphenidate and caffeine in the treatment of children with minimal brain dysfunction. The American journal of psychiatry, 1975, Volume: 132, Issue:7 Topics: Administration, Oral; Attention Deficit Disorder with Hyperactivity; Caffeine; Child; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Humans; Hyperkinesis; Male; Methylphenidate; Placebos; Psychological Tests; Remission, Spontaneous	1975
Caffeine versus methylphenidate and d-amphetamine in minimal brain dysfunction: a double-blind comparison. The American journal of psychiatry, 1975, Volume: 132, Issue:8 Topics: Amphetamine; Attention Deficit Disorder with Hyperactivity; Caffeine; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Methylphenidate; Placebos	1975
Caffeine in the treatment of children with minimal brain dysfunction or hyperkinetic syndrome. Psychosomatics, 1975, Volume: 16, Issue:1 Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Caffeine; Child; Child, Preschool; Clinical Trials as Topic; Dextroamphetamine; Humans; Hyperkinesis; Imipramine; Methylphenidate	1975
Chemical respirogenesis: a comparative study. Acta anaesthesiologica Scandinavica. Supplementum, 1973, Volume: 51 Topics: Adult; Aminobutyrates; Aminophylline; Bemegride; Benzamides; Blood Pressure; Caffeine; Central Nervous System Stimulants; Doxapram; Female; Humans; Lobeline; Methylphenidate; Nikethamide; Pentylenetetrazole; Placebos; Pulse; Quinolizines; Respiration; Respiratory Tract Diseases; Spirometry	1973
A research report on the anti-fatigue effects of magnesium pemoline. Psychopharmacologia, 1968, Volume: 13, Issue:5 Topics: Adult; Attention; Caffeine; Central Nervous System; Central Nervous System Stimulants; Fatigue; Female; Humans; Male; Methylphenidate; Oxazoles; Pemoline; Placebos; Problem Solving; Reaction Time; Stimulation, Chemical	1968
Heterocyclic amphetamine derivatives and caffeine on sleep in man. British journal of clinical pharmacology, 1980, Volume: 9, Issue:2 Topics: Adult; Amphetamines; Caffeine; Central Nervous System Stimulants; Electroencephalography; Humans; Male; Methylphenidate; Norbornanes; Pemoline; Pyrrolidines; Sleep; Sleep, REM	1980
Model insomnia by methylphenidate and caffeine and use in the evaluation of temazepam. Psychopharmacology, 1982, Volume: 76, Issue:3 Topics: Adult; Anti-Anxiety Agents; Caffeine; Drug Evaluation; Electroencephalography; Electrooculography; Humans; Male; Methylphenidate; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Temazepam	1982
Responses to methylphenidate and varied doses of caffeine in children with attention deficit disorder. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1981, Volume: 26, Issue:6 Topics: Attention Deficit Disorder with Hyperactivity; Caffeine; Child; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Male; Methylphenidate	1981
Contrasting actions of pressor agents in severe autonomic failure. The American journal of medicine, 1998, Volume: 105, Issue:2 Topics: Aged; Autonomic Agents; Blood Pressure; Caffeine; Catecholamines; Female; Heart Rate; Humans; Hypotension, Orthostatic; Ibuprofen; Indomethacin; Male; Methylphenidate; Phenylpropanolamine; Regression Analysis; Single-Blind Method; Yohimbine	1998
Methylphenidate, modafinil, and caffeine for cognitive enhancement in chess: A double-blind, randomised controlled trial. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2017, Volume: 27, Issue:3 Topics: Adult; Analysis of Variance; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Cross-Sectional Studies; Double-Blind Method; Female; Humans; Male; Methylphenidate; Middle Aged; Modafinil; Neuropsychological Tests; Retrospective Studies; Wakefulness-Promoting Agents	2017
Cognitive enhancement effects of stimulants: a randomized controlled trial testing methylphenidate, modafinil, and caffeine. Psychopharmacology, 2021, Volume: 238, Issue:2 Topics: Adult; Attention; Caffeine; Central Nervous System Stimulants; Cognition; Double-Blind Method; Fatigue; Humans; Male; Methylphenidate; Modafinil; Nootropic Agents; Pilot Projects; Treatment Outcome; Young Adult	2021
Memory enhancement with stimulants: Differential neural effects of methylphenidate, modafinil, and caffeine. A pilot study. Brain and cognition, 2021, Volume: 154 Topics: Adult; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Humans; Magnetic Resonance Imaging; Methylphenidate; Modafinil; Pilot Projects	2021
Cognitive enhancement: Effects of methylphenidate, modafinil, and caffeine on latent memory and resting state functional connectivity in healthy adults. Human brain mapping, 2022, 10-01, Volume: 43, Issue:14 Topics: Adult; Brain; Brain Mapping; Caffeine; Central Nervous System Stimulants; Cognition; Double-Blind Method; Humans; Magnetic Resonance Imaging; Male; Methylphenidate; Modafinil; Neural Pathways	2022

Other Studies

73 other study(ies) available for caffeine and methylphenidate

Article	Year
Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam. Journal of medicinal chemistry, 1984, Volume: 27, Issue:5 Topics: Amnesia; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Humans; Male; Mice; Mice, Inbred Strains; Pyrrolidines; Structure-Activity Relationship	1984
Cognition-activating properties of 3-(Aryloxy)pyridines. Journal of medicinal chemistry, 1981, Volume: 24, Issue:3 Topics: Animals; Cognition; Dose-Response Relationship, Drug; Male; Mice; Psychotropic Drugs; Pyridines; Structure-Activity Relationship	1981
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Four stimulants of the central nervous system: effects on short-term memory in young versus aged monkeys. Journal of the American Geriatrics Society, 1979, Volume: 27, Issue:7 Topics: Aging; Animals; Caffeine; Central Nervous System Stimulants; Female; Haplorhini; Macaca mulatta; Male; Memory, Short-Term; Methylphenidate; Nicotinic Acids; Pemoline; Pentylenetetrazole	1979
Influence of diethyldithiocarbamate (DDC) on the memory-facilitating effect of some central stimulants. Acta physiologica et pharmacologica Bulgarica, 1979, Volume: 5, Issue:1 Topics: Amphetamine; Animals; Avoidance Learning; Brain Chemistry; Caffeine; Ditiocarb; Drug Interactions; Male; Memory; Methylphenidate; Norepinephrine; Quinolines; Quinolones; Rats; Strychnine; Thiocarbamates; Time Factors	1979
Effects of chlordiazepoxide, CNS stimulants and their combinations on avoidance behaviour in mice. Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 215, Issue:2 Topics: Animals; Avoidance Learning; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Cocaine; Drug Interactions; Male; Methamphetamine; Methylphenidate; Mice; Pentylenetetrazole; Strychnine	1975
The effects of caffeine and methylphenidate on hyperactive children. Journal of the American Academy of Child Psychiatry, 1978,Summer, Volume: 17, Issue:3 Topics: Caffeine; Child; Double-Blind Method; Drug Evaluation; Female; Humans; Hyperkinesis; Male; Methylphenidate	1978
Effects of caffeine, methamphetamine and methylphenidate on reactions to novelty and activity in rats. Neuropharmacology, 1976, Volume: 15, Issue:11 Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Male; Methamphetamine; Methylphenidate; Motor Activity; Rats	1976
Differential effects of caffeine, D-amphetamine and methylphenidate on individual raphe cell fluorescence: a microspectrofluorimetric demonstration. Brain research, 1975, Feb-21, Volume: 85, Issue:1 Topics: Amphetamine; Animals; Caffeine; Male; Mesencephalon; Methylphenidate; Rats; Serotonin; Spectrometry, Fluorescence	1975
The effects of age and illumination on the dose-response curves for three stimulants. Psychopharmacologia, 1975, Volume: 40, Issue:4 Topics: Adaptation, Psychological; Aging; Animals; Arousal; Caffeine; Darkness; Dextroamphetamine; Dose-Response Relationship, Drug; Light; Male; Methylphenidate; Motor Activity; Rats; Rats, Inbred Strains	1975
Depletion of catecholamines in the brain of rats differentially affects stimulation of locomotor activity by caffeine, D-amphetamine, and methylphenidate. Neuropharmacology, 1990, Volume: 29, Issue:7 Topics: alpha-Methyltyrosine; Animals; Brain Chemistry; Caffeine; Catecholamines; Dextroamphetamine; Diencephalon; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Methylphenidate; Methyltyrosines; Motor Activity; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Reserpine; Telencephalon; Tyrosine 3-Monooxygenase	1990
[Characteristics of antagonism between ceruletide and various central-acting drugs: investigation by means of ambulatory activity in mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1990, Volume: 96, Issue:6 Topics: Animals; Bromocriptine; Caffeine; Ceruletide; Cocaine; Dose-Response Relationship, Drug; Drug Tolerance; Ephedrine; Haloperidol; Male; Methamphetamine; Methylphenidate; Mice; Morphine; Motor Activity; Scopolamine	1990
Discriminative stimulus properties of amphetamine and other stimulants in lead-exposed and normal rats. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:2 Topics: Amphetamine; Animals; Apomorphine; Body Weight; Caffeine; Central Nervous System Stimulants; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Stimulus; Lead; Lead Poisoning; Male; Methylphenidate; Rats	1986
Nursing alert. Understanding the spectrum of cerebral stimulants (continuing education). Nursing, 1985, Volume: 15, Issue:7 Topics: Amphetamines; Caffeine; Education, Nursing, Continuing; Humans; Methylphenidate; Pemoline; Synaptic Transmission	1985
Locus coeruleus as a target for psychogeriatric agents. Annals of the New York Academy of Sciences, 1985, Volume: 444 Topics: Amphetamine; Animals; Caffeine; Cerebral Cortex; Dihydroergotoxine; Dose-Response Relationship, Drug; Learning; Locus Coeruleus; Male; Memory; Methylphenidate; Neural Pathways; Neurons; Piracetam; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Septum Pellucidum; Vincamine	1985
Tolerance to behavioral effects of caffeine in rats. Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:2 Topics: Animals; Behavior, Animal; Caffeine; Drug Tolerance; Male; Methylphenidate; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Reinforcement Schedule	1988
Effects of psychoactive drugs on operant responding and non-operant activity of rats with hippocampal system damage. Brain research bulletin, 1986, Volume: 16, Issue:4 Topics: Animals; Behavior, Animal; Caffeine; Conditioning, Operant; Dextroamphetamine; Hippocampus; Imipramine; Male; Methylphenidate; Pentobarbital; Psychotropic Drugs; Rats; Rats, Inbred Strains; Sodium Chloride	1986
Difference in learning and retention by Albino Swiss mice. Part III. Effect of some brain stimulants. Methods and findings in experimental and clinical pharmacology, 1986, Volume: 8, Issue:6 Topics: Animals; Autonomic Agents; Caffeine; Learning; Male; Memory; Methylphenidate; Mice; Nicotine; Piperazines; Piracetam; Pyrrolidines	1986
Discriminative stimulus effects of caffeine: tolerance and cross-tolerance with methylphenidate. Life sciences, 1987, Jan-26, Volume: 40, Issue:4 Topics: Animals; Caffeine; Discrimination Learning; Drug Tolerance; Generalization, Stimulus; Male; Methylphenidate; Rats; Rats, Inbred Strains	1987
Correlations between electrical and pharmacological observations during anoxia in the rabbit, in normal and assisted respiration. Electroencephalography and clinical neurophysiology, 1971, Volume: 30, Issue:3 Topics: Amphetamine; Brain; Caffeine; Electroencephalography; Ethylamines; Hypoxia; Meclofenoxate; Methylphenidate; Pentylenetetrazole; Respiration; Respiration, Artificial; Theophylline	1971
[The chemical detection of doping among athletes]. Deutsche Zeitschrift fur die gesamte gerichtliche Medizin, 1966, Volume: 57, Issue:1 Topics: Aminobutyrates; Amphetamine; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Ephedrine; Forensic Medicine; Humans; Methylphenidate; Sports Medicine; Substance-Related Disorders; Toxicology; Urine	1966
[Studies of drug action on the behavior of small animals. I. Central nervous system stimulants and their combined effects]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1967, Volume: 87, Issue:7 Topics: Animals; Behavior, Animal; Caffeine; Lysergic Acid Diethylamide; Methamphetamine; Methylphenidate; Piperidines; Rats; Stimulation, Chemical	1967
[Psychopharmacologic agents and the sense of smell]. Monatsschrift fur Ohrenheilkunde und Laryngo-Rhinologie, 1968, Volume: 102, Issue:4 Topics: Amphetamine; Antidepressive Agents; Bromine; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Humans; Imipramine; Meclofenoxate; Meprobamate; Methylphenidate; Phenothiazines; Smell; Thioridazine; Tranquilizing Agents	1968
[Psychopharmacological agents and taste]. Monatsschrift fur Ohrenheilkunde und Laryngo-Rhinologie, 1968, Volume: 102, Issue:4 Topics: Amphetamine; Antidepressive Agents; Bromine; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Humans; Meclofenoxate; Meprobamate; Methylphenidate; Monoamine Oxidase Inhibitors; Nialamide; Phenothiazines; Taste; Tranquilizing Agents	1968
Species dependent effects of doxapram HCl on alcohol dehydrogenase activity. European journal of pharmacology, 1969, Volume: 6, Issue:2 Topics: Alcohol Oxidoreductases; Alcohols; Animals; Bemegride; Benzamides; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Dogs; Doxapram; Electrophoresis; Ethanol; Female; Glycols; Guinea Pigs; Horses; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Methylphenidate; Mice; Microsomes; Morpholines; Nikethamide; Pentylenetetrazole; Propylene Glycols; Pyrrolidinones; Rabbits; Rats; Species Specificity	1969
Stereotyped and non-stereotyped behaviour in rats induced by various stimulant drugs. Psychopharmacologia, 1969, Volume: 14, Issue:4 Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Caffeine; Central Nervous System; Cocaine; Lysergic Acid Diethylamide; Male; Methamphetamine; Methylphenidate; Nikethamide; Pemoline; Phenmetrazine; Piperidines; Rats	1969
[Pharmacological studies on 2-methyl-4-amino-6-methoxy-s-triazine (CV399); with special reference to its central effects]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Volume: 66, Issue:1 Topics: Amphetamine; Analgesics; Animals; Avoidance Learning; Behavior, Animal; Blood Pressure; Body Temperature; Brain Chemistry; Caffeine; Cats; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Drug Synergism; Ethanol; Haplorhini; Indoleacetic Acids; Male; Meprobamate; Methylphenidate; Mice; Morphine; Motor Activity; Pentobarbital; Piperidines; Rats; Reserpine; Respiration; Salivation; Seizures; Serotonin; Triazines	1970
Release of norepinephrine and normetanephrine from cat brain by central nervous system stimulants. Biochemical pharmacology, 1970, Volume: 19, Issue:9 Topics: Amphetamine; Animals; Brain; Caffeine; Cats; Chlorine; Cocaine; Dextroamphetamine; Ephedrine; Methylphenidate; Norepinephrine; Normetanephrine; Piperidines; Tritium	1970
Stimulant activity of pemoline and magnesium hydroxide. Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 181, Issue:2 Topics: Animals; Antacids; Ataxia; Caffeine; Cats; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Coma; Diazepam; Dogs; Drug Antagonism; Haplorhini; Hydroxides; Magnesium; Methamphetamine; Methylphenidate; Mice; Motor Activity; Pemoline; Pupil; Resins, Plant; Stimulation, Chemical; Tetrabenazine; Vomiting	1969
A psycho-pharmacological analysis of behaviour in rats. Japanese journal of pharmacology, 1971, Volume: 21, Issue:3 Topics: Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Grooming; Hallucinogens; Locomotion; Male; Mescaline; Methylphenidate; Pargyline; Pentylenetetrazole; Placebos; Rats; Statistics as Topic	1971
A survey of selected drugs on behavioral performance in ethanol-treated rats. European journal of pharmacology, 1971, Volume: 15, Issue:3 Topics: Amphetamine; Animals; Caffeine; Conditioning, Operant; Cyproheptadine; Drug Antagonism; Ethanol; Histamine H1 Antagonists; Imipramine; Male; Methylphenidate; Methyltyrosines; Pentylenetetrazole; Piperidines; Pyridines; Rats	1971
Personality and reactivity to stimulants and depressants. The Journal of nervous and mental disease, 1972, Volume: 154, Issue:6 Topics: Amobarbital; Antidepressive Agents; Benzoates; Caffeine; Cognition; Extraversion, Psychological; Female; Humans; Hypnotics and Sedatives; Introversion, Psychological; Male; Methylphenidate; MMPI; Motor Skills; Personality; Psychological Tests; Secobarbital	1972
Avoidance acquisition and CNS stimulants. Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 273, Issue:4 Topics: Animals; Avoidance Learning; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Discrimination Learning; Ephedrine; Male; Methamphetamine; Methylphenidate; Pemoline; Piperidines; Rats; Rats, Inbred Strains	1972
[Drug interference and incompatibilities of drugs attacking the central nervous system. 2. Stimulants]. Fortschritte der Medizin, 1973, May-10, Volume: 91, Issue:13 Topics: Caffeine; Central Nervous System; Drug Antagonism; Drug Interactions; Drug Synergism; Humans; Methamphetamine; Methylphenidate; Stimulation, Chemical; Sympathomimetics; Theophylline	1973
Caffeine as a substitute for Schedule II stimulants in hyperkinetic children. The American journal of psychiatry, 1973, Volume: 130, Issue:7 Topics: Caffeine; Child; Humans; Hyperkinesis; Male; Methylphenidate; Stimulation, Chemical	1973
[Trends and perspectives of psychopharmacology]. Zeitschrift fur arztliche Fortbildung, 1970, Oct-15, Volume: 64, Issue:20 Topics: Amphetamine; Antidepressive Agents; Caffeine; Hallucinogens; Humans; Hypnotics and Sedatives; Mental Disorders; Methylphenidate; Psychopharmacology; Tranquilizing Agents	1970
The hypnotic properties of 8-ethylthio-6-thiotheophylline sodium. Toxicology and applied pharmacology, 1968, Volume: 12, Issue:2 Topics: Amphetamine; Animals; Caffeine; Chloral Hydrate; Chlorpromazine; Dogs; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Meprobamate; Methylphenidate; Mice; Morphine; Nalorphine; Nikethamide; Pentobarbital; Pentylenetetrazole; Phenobarbital; Rabbits; Rats; Reserpine; Sleep; Theophylline; Thiopental	1968
[Intraventricular injection of drugs in the mouse]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1968, Volume: 88, Issue:2 Topics: Animals; Brain; Caffeine; Cerebral Ventricles; Injections; Male; Methamphetamine; Methods; Methylphenidate; Mice	1968
The effects of amphetamine, caffeine and methylphenidate on the locomotor activity of rats in an unfamiliar environment. International journal of neuropharmacology, 1968, Volume: 7, Issue:6 Topics: Amphetamine; Animals; Caffeine; Learning; Male; Methylphenidate; Motor Activity; Rats; Stimulation, Chemical	1968
Effect of certain drugs on the gamma-amino-butyric acid system of the central nervous system. Biochemical pharmacology, 1966, Volume: 15, Issue:1 Topics: Amino Alcohols; Aminobutyrates; Amobarbital; Animals; Brain; Butyrophenones; Caffeine; Carboxy-Lyases; Hypnotics and Sedatives; In Vitro Techniques; Meprobamate; Methylphenidate; Pentylenetetrazole; Picrotoxin; Rats; Subcellular Fractions; Transaminases	1966
Enhancement of conditioned photic evoked responses in the rabbit by pemoline and magnesium hydroxide. International journal of neuropsychiatry, 1967, Volume: 3, Issue:3 Topics: Animals; Caffeine; Cerebral Cortex; Conditioning, Psychological; Electroencephalography; Electrophysiology; Evoked Potentials; Light; Magnesium; Methamphetamine; Methylphenidate; Oxazoles; Pemoline; Rabbits	1967
Improvement of shuttle-box avoidance by combinations of orotic acid and central stimulants. Psychopharmacology, 1981, Volume: 73, Issue:4 Topics: Animals; Avoidance Learning; Caffeine; Central Nervous System Stimulants; Drug Synergism; Male; Memory; Methylphenidate; Orotic Acid; Rats; Retention, Psychology; Strychnine	1981
Play soliciting in juvenile male rats: effects of caffeine, amphetamine and methylphenidate. Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:4 Topics: Amphetamine; Animals; Caffeine; Central Nervous System Stimulants; Drug Interactions; Male; Methylphenidate; Play and Playthings; Rats; Scopolamine; Social Behavior; Time Factors	1983
Caffeine discrimination in the rat. Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:5 Topics: Animals; Caffeine; Conditioning, Operant; Dextroamphetamine; Generalization, Stimulus; Male; Methylphenidate; Motor Activity; Nicotine; Prejudice; Rats; Theophylline; Thyrotropin-Releasing Hormone	1981
[Effect of the psychostimulants caffeine and methylphenidate on the efficiency of physical activity in rats exposed to ionizing radiation]. Eksperimentalna meditsina i morfologiia, 1981, Volume: 20, Issue:2 Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Efficiency; Male; Methylphenidate; Physical Exertion; Radiation Injuries, Experimental; Rats; Swimming; Time Factors	1981
Enhanced attention in rhesus monkeys as a common factor for the cognitive effects of drugs with abuse potential. Psychopharmacology, 2003, Volume: 169, Issue:2 Topics: Animals; Atomoxetine Hydrochloride; Attention; Caffeine; Cognition; Cognition Disorders; Color Perception; Female; Macaca mulatta; Macaca nemestrina; Male; Methylphenidate; Morphine; Neuropsychological Tests; Nicotine; Nomifensine; Photic Stimulation; Propylamines; Substance-Related Disorders; Task Performance and Analysis	2003
The quest for a smart pill. Scientific American, 2003, Volume: 289, Issue:3 Topics: Alzheimer Disease; Animals; Behavior, Animal; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Cognition Disorders; Humans; Memory; Memory Disorders; Methylphenidate; Modafinil; Technology, Pharmaceutical	2003
Behavioral effects of caffeine, methamphetamine, and methylphenidate in the rat. Journal of the experimental analysis of behavior, 1963, Volume: 6 Topics: Animals; Caffeine; Central Nervous System Stimulants; Learning; Methamphetamine; Methylphenidate; Rats; Reinforcement, Psychology	1963
EFFECT OF STIMULANTS ON ISOLATED RATS. Archives internationales de pharmacodynamie et de therapie, 1963, Oct-01, Volume: 145 Topics: Amphetamine; Amphetamines; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Hydrazines; Methylphenidate; Noise; Pharmacology; Piperidines; Rats; Research; Tranylcypromine	1963
RELATIONSHIP BETWEEN CHOLINERGIC DRUGS AND EEG ACTIVATION. Archives internationales de pharmacodynamie et de therapie, 1963, Sep-01, Volume: 145 Topics: Atropine; Bemegride; Caffeine; Chlordiazepoxide; Chlorpromazine; Cholinergic Agents; Dextroamphetamine; Electroencephalography; Lysergic Acid Diethylamide; Methylphenidate; Morphine; Parasympathomimetics; Pentobarbital; Pentylenetetrazole; Pharmacology; Phenoxybenzamine; Physostigmine; Rabbits; Research	1963
MODIFICATION BY IONISING RADIATION OF THE CENTRAL NERVOUS REACTIVITY TO STIMULATING DRUGS. Activitas nervosa superior, 1963, Volume: 5 Topics: Amphetamine; Amphetamines; Caffeine; Central Nervous System; Electrocardiography; Electroencephalography; Methylphenidate; Mice; Pentylenetetrazole; Pharmacology; Rabbits; Radiation Injuries; Radiation Injuries, Experimental; Radiation, Ionizing; Rats; Research	1963
EFFECTS OF CENTRALLY ACTING DRUGS ON CONFINEMENT MOTOR ACTIVITY. Journal of pharmaceutical sciences, 1964, Volume: 53 Topics: Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Methylphenidate; Motor Activity; Movement; Pharmacology; Phenmetrazine; Piperidines; Prochlorperazine; Rats; Research; Tranylcypromine; Trifluoperazine	1964
DRUG-INDUCED DISSOCIATION BETWEEN EVOKED RETICULAR POTENTIALS AND THE EEG. Electroencephalography and clinical neurophysiology, 1965, Volume: 19 Topics: Amphetamine; Amphetamines; Animals; Antidepressive Agents; Atropine; Brain; Caffeine; Catechols; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Electroencephalography; Electrophysiology; Hallucinogens; Humans; Imipramine; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pentylenetetrazole; Phenoxybenzamine; Rabbits; Research; Reticular Formation; Scopolamine; Thioridazine; Tranquilizing Agents	1965
Differential effects of psychomotor stimulants on attentional performance in rats: nicotine, amphetamine, caffeine and methylphenidate. Behavioural pharmacology, 2004, Volume: 15, Issue:3 Topics: Amphetamine; Animals; Attention; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Male; Methylphenidate; Nicotine; Rats; Reaction Time	2004
[Caffeine, cannabis and cocaine: from automedication to 'automutilation' in adults with ADHD]. Nederlands tijdschrift voor geneeskunde, 2004, Dec-25, Volume: 148, Issue:52 Topics: Adult; Attention Deficit Disorder with Hyperactivity; Caffeine; Central Nervous System Stimulants; Cocaine-Related Disorders; Diagnosis, Differential; Female; Humans; Male; Marijuana Abuse; Methylphenidate; Substance-Related Disorders; Tobacco Use Disorder	2004
A new approach to Parkinson's disease combining caffeine, methylphenidate, and anticholinergic agents: case histories, pharmacological data, and a conceptual framework from traditional Chinese medicine. Hong Kong medical journal = Xianggang yi xue za zhi, 2006, Volume: 12, Issue:2 Topics: Adult; Aged; Antiparkinson Agents; Caffeine; Disorders of Excessive Somnolence; Drug Therapy, Combination; Humans; Male; Medicine, Chinese Traditional; Methylphenidate; Parkinson Disease	2006
Adenosine receptor antagonists improve short-term object-recognition ability of spontaneously hypertensive rats: a rodent model of attention-deficit hyperactivity disorder. Behavioural pharmacology, 2009, Volume: 20, Issue:2 Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Attention Deficit Disorder with Hyperactivity; Blood Pressure; Caffeine; Disease Models, Animal; Female; Male; Memory, Short-Term; Methylphenidate; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Adenosine A1; Receptors, Adenosine A2; Recognition, Psychology; Triazines; Triazoles; Xanthines	2009
Early long-term exposure with caffeine induces cross-sensitization to methylphenidate with involvement of DARPP-32 in adulthood of rats. Neurochemistry international, 2009, Volume: 55, Issue:5 Topics: Animals; Blotting, Western; Brain; Caffeine; Dopamine and cAMP-Regulated Phosphoprotein 32; Drug Interactions; Male; Methylphenidate; Motor Activity; Rats; Rats, Wistar	2009
Idiopathic hypersomnia: clinical features and response to treatment. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2009, Dec-15, Volume: 5, Issue:6 Topics: Actigraphy; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Female; Follow-Up Studies; Humans; Idiopathic Hypersomnia; Male; Methamphetamine; Methylphenidate; Modafinil; Pemoline; Polysomnography; Retrospective Studies; Sodium Oxybate; Treatment Outcome	2009
The effects of d-amphetamine, methylphenidate, sydnocarb, and caffeine on prepulse inhibition of the startle reflex in DBA/2 mice. Psychopharmacology, 2010, Volume: 211, Issue:3 Topics: Animals; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Dose-Response Relationship, Drug; Male; Methylphenidate; Mice; Mice, Inbred DBA; Noise; Sensory Gating; Sydnones	2010
Chronic caffeine treatment during prepubertal period confers long-term cognitive benefits in adult spontaneously hypertensive rats (SHR), an animal model of attention deficit hyperactivity disorder (ADHD). Behavioural brain research, 2010, Dec-20, Volume: 215, Issue:1 Topics: Analysis of Variance; Animals; Attention Deficit Disorder with Hyperactivity; Blood Pressure; Caffeine; Central Nervous System Stimulants; Cognition; Disease Models, Animal; Female; Learning; Methylphenidate; Motor Activity; Rats; Rats, Inbred SHR; Rats, Wistar; Recognition, Psychology	2010
Social isolation induces deficit of latent learning performance in mice: a putative animal model of attention deficit/hyperactivity disorder. Behavioural brain research, 2013, Feb-01, Volume: 238 Topics: Aggression; Animals; Attention; Attention Deficit Disorder with Hyperactivity; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Fear; Female; Learning; Male; Methylphenidate; Mice; Mice, Inbred ICR; Motor Activity; Recognition, Psychology; Social Isolation; Spatial Behavior	2013
Pharmacological classification of herbal extracts by means of comparison to spectral EEG signatures induced by synthetic drugs in the freely moving rat. Journal of ethnopharmacology, 2013, Sep-16, Volume: 149, Issue:2 Topics: Animals; Brain; Caffeine; Electroencephalography; Magnoliopsida; Methylphenidate; Paroxetine; Phenytoin; Plant Extracts; Rats; Tramadol	2013
A preliminary study on cognitive enhancer consumption behaviors and motives of French Medicine and Pharmacology students. European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:13 Topics: Adolescent; Adult; Ascorbic Acid; Benzhydryl Compounds; Caffeine; Education, Medical; Female; France; Humans; Illicit Drugs; Male; Methamphetamine; Methylphenidate; Modafinil; Nootropic Agents; Pharmacology; Piracetam; Prevalence; Students, Health Occupations; Surveys and Questionnaires; Young Adult	2014
The billion dollar business of being smart. BMJ (Clinical research ed.), 2015, Sep-14, Volume: 351 Topics: Amphetamine; Attention Deficit Disorder with Hyperactivity; Caffeine; Central Nervous System Stimulants; Energy Drinks; Humans; Methylphenidate; United States	2015
Smart drugs: A dose of intelligence. Nature, 2016, Mar-03, Volume: 531, Issue:7592 Topics: Aging; Amphetamines; Animals; Benzhydryl Compounds; Biomedical Enhancement; Caffeine; Child; Cognition; Dopamine; Healthy Volunteers; Humans; Intelligence; Intelligence Tests; Methylphenidate; Modafinil; Neurotransmitter Agents; Nicotine; Norepinephrine; Off-Label Use; Performance-Enhancing Substances; Prefrontal Cortex; Rats; Substance-Related Disorders; Video Games	2016
Stimulants cocktail: Methylphenidate plus caffeine impairs memory and cognition and alters mitochondrial and oxidative status. Progress in neuro-psychopharmacology & biological psychiatry, 2021, 03-02, Volume: 106 Topics: Animals; Caffeine; Central Nervous System Stimulants; Cognition; Cognitive Dysfunction; Female; Male; Maze Learning; Memory Disorders; Methylphenidate; Mitochondria; Oxidative Stress; Zebrafish	2021