caffeine has been researched along with methadone in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (31.43) | 18.7374 |
| 1990's | 1 (2.86) | 18.2507 |
| 2000's | 9 (25.71) | 29.6817 |
| 2010's | 13 (37.14) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Geber, WF; Hung, CY; Lefkowitz, SS | 1 |
| Falek, A; Glick, JH; Madden, JJ; Shafer, DA | 1 |
| Lefkowitz, SS; Nemeth, D | 1 |
| Bauer, G; Konzett, H; Ziegler, E | 1 |
| Jurand, J; Knox, JH | 1 |
| Gorodetzky, CW; Kullberg, MP | 1 |
| Abola, EE; Deutsch, HF; Edmundson, AB; Ely, KR; Fausch, MD; Girling, RL; Schiffer, M; Westholm, FA | 1 |
| Baden, MM; Valanju, NN; Valanju, SN; Verma, SK | 1 |
| Frank, GB; Rohani, F | 1 |
| Agustí, M; Carrero, EJ; Fábregas, N; Fernández, C; Valldeoriola, F | 1 |
| JACOB, J; MICHAUD, G | 1 |
| Beijnen, JH; de Jonge, ME; den Hoed, R; Hendriks, VM; Huitema, AD; Sparidans, RW; van den Brink, W; van Ree, JM; Zandvliet, AS | 1 |
| De Giovanni, N; Fucci, N; Scarlata, S | 1 |
| Bertol, E; Mari, F; Politi, L | 1 |
| Iqbal, MZ; Lagundoye, O; Lennard, MS; Rostami-Hodjegan, A; Seivewright, N; Shiran, MR; Tucker, GT | 1 |
| Galceran, MT; Huerta-Fontela, M; Rosa Boleda, M; Ventura, F | 1 |
| Drennan, D; Farahmand, N; Junkins, S | 1 |
| Barbera, N; Busardò, FP; Indorato, F; Romano, G | 1 |
| Cooley, J; Lopez-Avila, V; Thevis, M; Urdahl, R | 1 |
| Akhtar, S; Desai, A; Goldwater, R; Han, D; Howieson, C; Kowalski, D; Lademacher, C; Pearlman, H; Rammelsberg, D; Townsend, R; Yamazaki, T | 1 |
| Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE | 1 |
| Csorba, J; Figeczki, T; Gyarmathy, VA; Kiss, J; Medgyesi-Frank, K; Péterfi, A; Posta, J | 2 |
| Alavi Nikje, MM; Soleimani, M; Tavakoli, Z | 1 |
| Carnevale Miino, M; Chorazy, T; Halešová, T; Hlavínek, P; Macsek, T | 1 |
1 review(s) available for caffeine and methadone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for caffeine and methadone
| Article | Year |
|---|---|
Population pharmacokinetics of caffeine and its metabolites theobromine, paraxanthine and theophylline after inhalation in combination with diacetylmorphine.
Topics: Administration, Inhalation; Administration, Oral; Biological Availability; Caffeine; Central Nervous System Stimulants; Drug Combinations; Drug Interactions; Half-Life; Heroin; Heroin Dependence; Humans; Injections, Intravenous; Methadone; Narcotics; Population; Theobromine; Theophylline | 2005 |
Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects.
Topics: Adult; Area Under Curve; Bupropion; Caffeine; Carbamates; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Interactions; Female; Healthy Volunteers; Humans; Male; Methadone; Middle Aged; Nitriles; Piperidines; Pyridines; Triazoles; Young Adult | 2017 |
32 other study(ies) available for caffeine and methadone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Effect of morphine, hydromorphone, methadone, mescaline, trypan blue, vitamin A, sodium salicylate, and caffeine on the serum interferon level in response to viral infection.
Topics: Animals; Caffeine; Hydromorphone; Interferons; Male; Mescaline; Methadone; Mice; Morphine; Salicylates; Trypan Blue; Vesicular stomatitis Indiana virus; Virus Diseases; Vitamin A | 1975 |
Effects of opiates and demographic factors on DNA repair synthesis in human leukocytes.
Topics: Adolescent; Adult; Age Factors; Caffeine; DNA Repair; Female; Heroin Dependence; Humans; Leukocytes; Male; Methadone; Middle Aged; Sex Factors; Smoking; Ultraviolet Rays | 1979 |
Immunosuppression of rosette-forming cells.
Topics: Amphetamine; Animals; Body Weight; Caffeine; Erythrocytes; Humans; Immunity; Immunologic Techniques; Immunosuppression Therapy; Leukocytes; Male; Methadone; Mice; Morphine; Organ Size; Pentobarbital; Phenobarbital; Sheep; Spleen; Substance-Related Disorders | 1976 |
Drugs in breast milk.
Topics: Anticoagulants; Anticonvulsants; Antineoplastic Agents; Antithyroid Agents; Aspirin; Atropine; Caffeine; Chloramphenicol; Chlorothiazide; Contraceptives, Oral; Ergot Alkaloids; Ethanol; Female; Humans; Hypnotics and Sedatives; Methadone; Milk, Human; Nalidixic Acid; Narcotics; Penicillins; Quinine; Reserpine; Sulfonamides; Tetracycline | 1974 |
[On the inhibitory effect of kinins on isolated intestinal sections].
Topics: Anesthetics, Local; Animals; Atropine; Bradykinin; Caffeine; Duodenum; Ganglionic Blockers; Guanethidine; Ileum; Jejunum; Kallidin; Meperidine; Methadone; Morphine; Phenylbutazone; Rabbits | 1966 |
Separation of morphine alkaloids, heroin, methadone and other drugs by ion-exchange chromatography.
Topics: Acetaminophen; Aspirin; Autoanalysis; Caffeine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Heroin; Methadone; Methods; Morphine; Opium; Phenacetin; Solvents | 1973 |
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cocaine; Codeine; Evaluation Studies as Topic; Glucuronates; Humans; Hydrolysis; Meperidine; Meprobamate; Mescaline; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Naloxone; Pentobarbital; Secobarbital; Substance-Related Disorders | 1974 |
Binding of 2,4-dinitrophenyl compounds and other small molecules to a crystalline lambda-type Bence-Jones dimer.
Topics: Amino Acid Sequence; Amino Acids; Amyloidosis; Bence Jones Protein; Binding Sites; Caffeine; Chemical Phenomena; Chemistry; Colchicine; Dansyl Compounds; Fluorine; Humans; Immunoglobulin Fragments; Immunoglobulins; Iodine; Macromolecular Substances; Methadone; Models, Structural; Morphine; Nitrobenzenes; Phenanthrolines; Protein Binding; Protein Conformation; Uracil; Vitamin K; X-Ray Diffraction | 1974 |
Confirmed identification of biotransformed drugs of abuse in urine.
Topics: Amphetamine; Analgesics; Barbiturates; Biotransformation; Caffeine; Cannabis; Chromatography, Gas; Chromatography, Thin Layer; Codeine; Humans; Hydrogen-Ion Concentration; Imipramine; Indicators and Reagents; Methadone; Morphine; Nicotine; Pharmaceutical Preparations; Procaine; Skin; Spectrum Analysis; Substance-Related Disorders; Tranquilizing Agents | 1972 |
Calcium antagonism of an opiate drug effect on an excitable cell membrane.
Topics: Action Potentials; Animals; Caffeine; Calcium; Cell Membrane; Methadone; Rana pipiens; Receptors, Opioid; Tetrodotoxin | 1983 |
Unilateral trigeminal and facial nerve palsies associated with epidural analgesia in labour.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bupivacaine; Caffeine; Central Nervous System Stimulants; Cranial Nerve Diseases; Facial Paralysis; Female; Fluid Therapy; Headache; Humans; Infant, Newborn; Intracranial Hypotension; Lysine; Methadone; Narcotics; Obstetric Labor, Premature; Opioid-Related Disorders; Palliative Care; Paralysis; Pregnancy; Spinal Puncture; Syndrome; Trigeminal Nerve | 1998 |
[The effect of various pharmacological agents (amphetamine, cocaine, caffeine, hexobarbital, meprobamate, morphine, dextromoramide, 1-methadone, pethidine and CT 3570) on the time of exhaustion and behavior of animals swimming at 20 degrees C].
Topics: Amphetamine; Amphetamines; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior; Caffeine; Central Nervous System Stimulants; Cocaine; Dextromoramide; Hexobarbital; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed | 1960 |
Sweat testing in addicts under methadone treatment: an Italian experience.
Topics: Aged; Aged, 80 and over; Caffeine; Central Nervous System Stimulants; Cocaine; Cotinine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Hair; Heroin Dependence; Humans; Italy; Male; Methadone; Middle Aged; Narcotics; Nicotine; Pyrrolidines; Sweat | 2008 |
Nails of newborns in monitoring drug exposure during pregnancy.
Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Cotinine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methadone; Morphine; Nails; Narcotics; Nicotine; Nicotinic Agonists; Pregnancy; Smoking | 2008 |
Contribution of the activities of CYP3A, CYP2D6, CYP1A2 and other potential covariates to the disposition of methadone in patients undergoing methadone maintenance treatment.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Biomarkers; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Dextromethorphan; Dextrorphan; Female; Humans; Isomerism; Male; Methadone; Midazolam; Middle Aged; Narcotics; Opioid-Related Disorders; Saliva; Young Adult | 2009 |
Evaluation of the presence of drugs of abuse in tap waters.
Topics: Caffeine; Chromatography, High Pressure Liquid; Cocaine; Cotinine; Drinking Water; Environmental Monitoring; Illicit Drugs; Methadone; Nicotine; Pyrrolidines; Spectrometry, Mass, Electrospray Ionization | 2011 |
Patient education and self-advocacy: queries and responses on pain management.
Topics: Caffeine; Chronic Pain; Headache; Humans; Methadone; Pain Management; Sleep Apnea Syndromes | 2008 |
The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome.
Topics: Adult; Anesthetics, Local; Antitussive Agents; Bile; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Citalopram; Codeine; Dextromethorphan; Drug Contamination; Drug Overdose; Drug Users; Female; Forensic Pathology; Forensic Toxicology; Gastrointestinal Contents; Humans; Illicit Drugs; Kidney; Lidocaine; Liver; Lung; Male; Methadone; Morphine; Morphine Derivatives; Narcotics; Pyrrolidines; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders; Vitreous Body | 2013 |
Determination of stimulants using gas chromatography/high-resolution time-of-flight mass spectrometry and a soft ionization source.
Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Codeine; Dopamine Uptake Inhibitors; Equipment Design; GABA Antagonists; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Ions; Methadone; Narcotics; Nicotine; Nikethamide; Norbornanes; Pentylenetetrazole; Phenmetrazine; Sensitivity and Specificity | 2012 |
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine | 2016 |
Drug residues in syringes and other injecting paraphernalia in Hungary.
Topics: Alkaloids; Caffeine; Drug Residues; Europe; Humans; Hungary; Methadone; Prevalence; Syringes | 2018 |
Diverted medications and new psychoactive substances-A chemical network analysis of discarded injecting paraphernalia in Hungary.
Topics: Benzoic Acid; Caffeine; Humans; Hungary; Illicit Drugs; Methadone; Needle Sharing; Opiate Substitution Treatment; Prescription Drug Diversion; Prevalence; Psychotropic Drugs; Substance Abuse, Intravenous; Syringes | 2017 |
Characterization and performance evaluation of functional monomer effect on molecular imprinted polyurethane foam.
Topics: Alprazolam; Caffeine; Chromatography, High Pressure Liquid; Drug Monitoring; Hydrogen-Ion Concentration; Methadone; Molecular Imprinting; Polymers; Polyurethanes; Salts; Solid Phase Extraction | 2019 |
Pharmaceutical and narcotics monitoring in Brno wastewater system and estimation of seasonal effect on the abuse of illicit drugs by a wastewater-based epidemiology approach.
Topics: Amphetamine; Caffeine; Cocaine; Environmental Monitoring; Heroin; Humans; Illicit Drugs; Methadone; Methamphetamine; Narcotics; Seasons; Substance Abuse Detection; Substance-Related Disorders; Wastewater; Wastewater-Based Epidemiological Monitoring; Water Pollutants, Chemical | 2023 |