Compounds > caffeine

caffeine and lorazepam

caffeine has been researched along with lorazepam in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (20.00)	18.7374
1990's	4 (20.00)	18.2507
2000's	10 (50.00)	29.6817
2010's	2 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Coassolo, P; Lavé, T; Schneider, G	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Junien, JL; Wettstein, JG	1
Breen, K; Swartz, CM; Wahby, VS	1
Johnson, RF; Meredith, CG; Schenker, S; Secor, JW; Snowdy, P; Speeg, KV	1
Ator, NA; Griffiths, RR	1
Bond, AJ; File, SE; Lister, RG	1
Ahmaidi, SB; Audran, MA; Caillaud, CF; Chanal, JL; Collomp, KR; Préfaut, CG	1
Donnelly, CL; McEvoy, JP; Narasimhachari, N; Wilson, WH	1

Reviews

1 review(s) available for caffeine and lorazepam

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

3 trial(s) available for caffeine and lorazepam

Article	Year
Pharmacologic provocation and dexamethasone suppression test sensitivity. Neuropsychobiology, 1989, Volume: 22, Issue:1 Topics: Caffeine; Depressive Disorder; Dexamethasone; Electroconvulsive Therapy; Humans; Hydrocortisone; Lorazepam; Prognosis; Randomized Controlled Trials as Topic; Theophylline	1989
Interaction between effects of caffeine and lorazepam in performance tests and self-ratings. Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:2 Topics: Adult; Anti-Anxiety Agents; Anxiety; Caffeine; Drug Interactions; Emotions; Female; Flicker Fusion; Humans; Lorazepam; Male; Placebos; Psychological Tests; Self-Assessment; Verbal Learning	1982
A study of the potential confounding effects of diet, caffeine, nicotine and lorazepam on the stability of plasma and urinary homovanillic acid levels in patients with schizophrenia. Biological psychiatry, 1996, Dec-15, Volume: 40, Issue:12 Topics: Adult; Caffeine; Central Nervous System Stimulants; Diet; Drug Interactions; GABA Modulators; Homovanillic Acid; Humans; Lorazepam; Male; Nicotine; Nicotinic Agonists; Psychiatric Status Rating Scales; Schizophrenia; Time Factors	1996

Other Studies

16 other study(ies) available for caffeine and lorazepam

Article	Year
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques. Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25 Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats	1999
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogPoct: a tool for lipophilicity determination in drug discovery. Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Effects of 5-HT3 antagonists on fixed-interval behavior in rats. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:3 Topics: Animals; Behavior, Animal; Caffeine; Cocaine; Drug Interactions; Lorazepam; Male; Rats; Rats, Inbred Strains; Serotonin Antagonists	1992
Lack of effect of nizatidine on hepatic drug metabolism in man. British journal of clinical pharmacology, 1985, Volume: 20, Issue:6 Topics: Adult; Blood Proteins; Caffeine; Chlordiazepoxide; Histamine H2 Antagonists; Humans; Kinetics; Liver; Lorazepam; Male; Nizatidine; Pharmaceutical Preparations; Protein Binding; Theophylline; Thiazoles	1985
Lorazepam and pentobarbital discrimination: interactions with CGS 8216 and caffeine. European journal of pharmacology, 1985, Jan-02, Volume: 107, Issue:2 Topics: Animals; Caffeine; Conditioning, Operant; Convulsants; Discrimination Learning; Dose-Response Relationship, Drug; Lorazepam; Male; Papio; Pentobarbital; Pyrazoles; Rats; Species Specificity	1985
Effects of benzodiazepine during a Wingate test: interaction with caffeine. Medicine and science in sports and exercise, 1993, Volume: 25, Issue:12 Topics: Adult; Benzodiazepines; Caffeine; Catecholamines; Energy Metabolism; Exercise; Female; Humans; Lactates; Lorazepam; Male; Physical Exertion	1993