caffeine has been researched along with ibuprofen in 134 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.99) | 18.7374 |
| 1990's | 11 (8.21) | 18.2507 |
| 2000's | 38 (28.36) | 29.6817 |
| 2010's | 60 (44.78) | 24.3611 |
| 2020's | 21 (15.67) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Akamatsu, M | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Carroll, D; Guest, P; Juniper, RP; McQuay, HJ; Moore, RA | 1 |
| Beaver, WT; Forbes, JA; Gongloff, CM; Jones, KF; Kehm, CJ; Smith, JW; Smith, WK; Zeleznock, JR | 1 |
| Habib, S; Levers, BG; Matthews, RW; Scully, C; Shepherd, JP | 1 |
| Turcotte, JY | 1 |
| Bird, HA | 1 |
| Masson, EL; Squires, DJ | 1 |
| Babington, MA; Monson, RA | 1 |
| Kondo, T; Lin, Z; Nagano, T; Nakaya, T; Nishigami, J; Ohshima, T; Sawaguchi, T; Takayasu, T | 1 |
| Hamilton, J | 1 |
| Angell, K; Carroll, D; Juniper, RP; McQuay, HJ; Moore, RA | 1 |
| Khalil, RM | 1 |
| Carrive, P; Meyer-Carrive, I | 1 |
| Po, AL; Zhang, WY | 1 |
| Biaggioni, I; Black, BK; Jordan, J; Norman, R; Robertson, D; Shannon, JR | 1 |
| Furukawa, M; Kataoka, H; Koyama, R; Nakatsugi, S; Tanaka, Y | 1 |
| Balm, TK; Diamond, S; Freitag, FG | 1 |
| Sparano, N | 1 |
| Golub, MS; Hori, MT; Kanda, H; Tuck, ML | 1 |
| Diamond, S; Freitag, FG | 1 |
| Kiersch, TA; Minić, MR | 1 |
| Rollins, G | 1 |
| Drewe, J; Haefeli, WE; Krähenbühl, S; Vrtic, F; Wenk, M | 1 |
| Berger, U; Hühnerfuss, H; Jensen, E; Kallenborn, R; Thoresen, H; Weigel, S | 1 |
| Bock, U; Haltner, E; Krause, W; Otto, J | 1 |
| Foster, GD; Thomas, PM | 1 |
| Croker, B; Ejaz, AA; Johnson, RJ; Munjal, S; Sekhon, I | 1 |
| Lawrence, JR; Neu, TR; Swerhone, GD; Wassenaar, LI | 1 |
| English, JC; Swanson, JK | 1 |
| Goldstein, J; Lipton, RB; Ryan, RE; Saper, JR; Silberstein, SD | 1 |
| André, C; Blaise, C; Gagné, F; Salazar, M | 1 |
| Agren, H; Bondesson, L; Garberg, P; Luo, Y; Mikkelsen, KV | 1 |
| Bravo, G; Cook, HJ; Déciga-Campos, M; Díaz-Reval, MI; Domínguez-Ramírez, AM; López, JR; López-Muñoz, FJ | 1 |
| Haag, G | 1 |
| Hancock, DB; Jewett, R; Martin, ER; Scott, BL; Scott, WK; Stacy, MA; Stajich, JM; Vance, JM | 1 |
| Brna, PM; Dooley, JM; Fraser, A; Gordon, KE; MacSween, J; Wood, EP | 1 |
| Bondesson, L; Luo, Y; Rudberg, E; Sałek, P | 1 |
| Abdollahi, H; Khoshayand, MR; Mohammadi, A; Saadatfard, A; Shariatpanahi, M | 1 |
| Inglis, K; Mitchell, A; Porter, G; van Zanten, SV | 1 |
| Hadgraft, J; Lane, ME; Mitchell, J; Russeau, W; Tetteh, J | 1 |
| Rashwan, WA | 1 |
| Bigal, M; Lipton, RB; Scher, AI; Stewart, WF | 1 |
| Chia, M; Corallo, CE; Ernest, D | 1 |
| Attygalle, AB; Bolgar, MS; Chan, CC; Miller, SA | 1 |
| Fink, G; Martineau, C; Saito, K; Taulelle, F | 1 |
| Abbott, PV; Asgar, K; Delvarani, A; Karamifar, K; Khabazi, H; Kharazifard, MJ; Lotfi, M; Mehrvarzfar, P; Saghiri, MA | 1 |
| Alhaique, F; Carafa, M; Coviello, T; Di Marzio, L; Marianecci, C; Matricardi, P; Meo, C; Rinaldi, F | 1 |
| Derry, CJ; Derry, S; Moore, RA | 2 |
| Finnin, BC; Gee, CM; Nicolazzo, JA; Watkinson, AC | 1 |
| Gersberg, RM; Hua, T; Jinadasa, KB; Tan, SK; Zhang, DQ; Zhu, J | 1 |
| Inglis, K; McCrea, P; Mitchell, A; Porter, G | 1 |
| Carriquiriborde, P; Elorriaga, Y; Marino, DJ; Ronco, AE | 1 |
| Clarke, GS; Kazarian, SG; Wray, PS | 1 |
| Berka, K; Otyepka, M; Paloncýová, M | 1 |
| Blondeel, P; Boonen, J; De Saeger, S; De Spiegeleer, B; Malysheva, SV; Mavungu, JD; Roche, N; Taevernier, L; Veryser, L | 1 |
| Gardinali, PR; Wang, J | 1 |
| Burdette, CQ; Manard, BT; Marcus, RK; Zhang, LX | 1 |
| Micov, AM; Stepanović-Petrović, RM; Tomić, MA | 1 |
| Mu, B; O'Donnell, KP; Sheskey, PJ; Thompson, MR; Weatherley, S | 1 |
| Aarons, L; Johnson, TN; Ogungbenro, K; Rostami-Hodjegan, A; Salem, F; Vajjah, P | 1 |
| Aguirre-Martínez, GV; Buratti, S; DelValls, AT; Fabbr, E; Martín-Díaz, ML | 1 |
| Nutt, DJ; Smith, AP | 1 |
| Gold, M; Goldstein, J; Hagen, M | 1 |
| Boonen, J; De Spiegeleer, B; Guillaume, J; Risseeuw, M; Roche, N; Shah, SN; Taevernier, L; Van Calenbergh, S; Veryser, L | 1 |
| Nacapricha, D; Saetear, P; Teerasong, S; Wattanasin, P; Wilairat, P | 1 |
| Chaves, SC; Cunha, RR; Dos Santos, WT; Muñoz, RA; Ribeiro, MM; Richter, EM; Torres, LM | 1 |
| Aguirre-Martínez, GV; DelValls, AT; Laura Martín-Díaz, M | 1 |
| Derry, S; Moore, RA; Wiffen, PJ | 1 |
| Aguirre-Martínez, GV; DelValls, TA; Martín-Díaz, ML | 1 |
| Bergese, S; Castellon-Larios, K | 1 |
| Groza, LG; Hebig, KH; Ptacek, CJ; Sabourin, MJ; Scheytt, TJ | 1 |
| Alexandre, C; Ferreira, A; Latremoliere, A; Miracca, G; Scammell, TE; Woolf, CJ; Yamamoto, M | 1 |
| Hegewisch, A; Lange, R; Muse, DD; Richter, E; Weiser, T | 1 |
| Bansiwal, A; Hippargi, G; Kaur, H; Pophali, GR | 1 |
| Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS | 1 |
| Aguirre-Martínez, GV; André, C; Gagné, F; Martín-Díaz, LM | 1 |
| Berger, L; Glass, BD; Llewelyn, VK | 4 |
| Edwards, QA; Garner-O'Neale, LD; Kulikov, SM; Metcalfe, CD; Sultana, T; Yargeau, V | 1 |
| Demiri, V; Khinast, J; Lingitz, J; Piller, M; Rinner, P; Sacher, S; Salar-Behzadi, S; Stranzinger, S | 1 |
| Adib Rad, H; Bakouei, F; Basirat, Z; Farhadi Kotenaei, Z; Kazemi, S; Khafri, S; Moghadamnia, AA; Nikpour, M | 1 |
| Lange, R; Mück, T; Schepers, C; Weiser, T | 1 |
| Colón, I; Medendorp, J; Ryan, T | 1 |
| Alonso, C; Barba, C; Carrer, V; Coderch, L; Martí, M; Yousef, I | 1 |
| Ariño, C; Castilla, Ò; Díaz-Cruz, JM; Diaz-Cruz, MS; Serrano, N | 1 |
| Abduljalil, K; Jamei, M; Johnson, TN; Pan, X; Pansari, A | 1 |
| Musselman, E; Stannard, D | 1 |
| Almeida, TS; Carvalho, JPF; Freire, CSR; Mota, JP; Rosado, C; Silva, NHCS; Silvestre, AJD; Vilela, C | 1 |
| Förderreuther, S; Hitier, S; Lampert, A; Lange, R; Weiser, T | 1 |
| Bhatt-Mehta, V; Schumacher, RE | 1 |
| Lampert, A; Lange, R; Weiser, T | 1 |
| Björklund, E; Jankowska, K; Lambropoulou, D; Luczkiewicz, A; Nannou, C; Polkowska, Ż; Potapowicz, J; Svahn, O; Szopińska, M | 1 |
| Nguyen, GCD; Nguyen, QTT; Tran, AMT; Tran, BT; Tran, TN | 1 |
| Draz, ME; El Enany, N; El Sherbiny, D; Wahba, MEK | 1 |
| Chand, N; Kumar, K; Singh, V; Suthar, S | 1 |
| Abdool-Ghany, AA; Gidley, ML; Klaus, J; Sahwell, PJ; Sinigalliano, CD; Solo-Gabriele, HM | 1 |
| Lau, CI; Wang, YF | 1 |
| Gadžurić, S; Gligorić, E; Grujić-Letić, N; Teofilović, B; Vraneš, M | 1 |
| Corvini, PF; Demaria, F; Kolvenbach, BA; Suleiman, M; Zimmardi, C | 1 |
| Araya-Valverde, E; Balcázar, JL; Briceño-Guevara, S; Cambronero-Heinrichs, JC; Masis-Mora, M; Mendez-Rivera, M; Montiel-Mora, JR; Ramírez-Morales, D; Rodríguez-Rodríguez, CE; Sànchez-Melsió, A; Soto-Garita, C | 1 |
| Goh, R; Kitagawa, S; Li, X; Lim, CC; Lim, JYC; Lin, Q; Loh, XJ; Otake, KI; Tan, TTY | 1 |
| Barbieri, MV; Chiron, S; Chkirbene, A; Gómez-Navarro, O; Khadhar, S; Khezami, F; Khiari, N; Pérez, S | 1 |
| Masís-Mora, M; Méndez-Rivera, M; Montiel-Mora, JR; Ramírez-Morales, D; Rodríguez-Rodríguez, CE | 1 |
| Andeen, NK; Eiwaz, MB; Groat, T; Hebert, JF; Hutchens, MP; Munhall, AC; Nickerson, MN; Pai, AA | 1 |
8 review(s) available for caffeine and ibuprofen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Analgesic efficacy of ibuprofen alone and in combination with codeine or caffeine in post-surgical pain: a meta-analysis.
Topics: Adult; Anesthetics, Combined; Caffeine; Codeine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Ibuprofen; Pain, Postoperative; Randomized Controlled Trials as Topic; Sleep Stages | 1998 |
The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/ caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis).
Topics: Adult; Antipyrine; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Phenacetin; Placebo Effect; Pyridones; Single-Blind Method; Toothache | 2002 |
[Self-medication of migraine and headache].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Controlled Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Evaluation Studies as Topic; Humans; Ibuprofen; Migraine Disorders; Practice Guidelines as Topic; Self Medication; Serotonin Receptor Agonists; Sumatriptan; Tablets; Tension-Type Headache; Vasoconstrictor Agents | 2006 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Caffeine; Chemotherapy, Adjuvant; Female; Headache; Humans; Ibuprofen; Pain, Postoperative; Postpartum Period; Pregnancy; Randomized Controlled Trials as Topic | 2012 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Analgesics; Caffeine; Chemotherapy, Adjuvant; Diclofenac; Drug Synergism; Dysmenorrhea; Female; Headache; Humans; Ibuprofen; Male; Middle Aged; ortho-Aminobenzoates; Pain, Postoperative; Postpartum Period; Pregnancy; Randomized Controlled Trials as Topic | 2014 |
Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics, Non-Narcotic; Caffeine; Drug Combinations; Humans; Ibuprofen; Numbers Needed To Treat; Pain, Postoperative; Randomized Controlled Trials as Topic | 2015 |
Caffeine in the management of patients with headache.
Topics: Abdominal Pain; Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Central Nervous System Stimulants; Headache; Humans; Ibuprofen; Migraine Disorders; Randomized Controlled Trials as Topic; Tension-Type Headache | 2017 |
23 trial(s) available for caffeine and ibuprofen
| Article | Year |
|---|---|
A multiple dose comparison of combinations of ibuprofen and codeine and paracetamol, codeine and caffeine after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Caffeine; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Molar, Third; Pain Measurement; Pain, Postoperative | 1992 |
Effect of caffeine on ibuprofen analgesia in postoperative oral surgery pain.
Topics: Adolescent; Adult; Analgesia; Analysis of Variance; Caffeine; Dentistry, Operative; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Pain, Postoperative; Postoperative Care; Time Factors; Tooth Extraction | 1991 |
A study of the comparative efficacy of four common analgesics in the control of postsurgical dental pain.
Topics: Acetaminophen; Adult; Analgesics; Analysis of Variance; Aspirin; Caffeine; Codeine; Drug Combinations; Female; Humans; Ibuprofen; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Random Allocation; Single-Blind Method; Tooth Extraction; Tooth, Impacted | 1990 |
A double-blind comparison of ibuprofen, ASA-codeine-caffeine compound and placebo in the treatment of dental surgery pain.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Pain, Postoperative; Placebos; Random Allocation; Surgery, Oral | 1981 |
Ibuprofen compared with ibuprofen plus caffeine after third molar surgery.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Tooth Extraction | 1996 |
Contrasting actions of pressor agents in severe autonomic failure.
Topics: Aged; Autonomic Agents; Blood Pressure; Caffeine; Catecholamines; Female; Heart Rate; Humans; Hypotension, Orthostatic; Ibuprofen; Indomethacin; Male; Methylphenidate; Phenylpropanolamine; Regression Analysis; Single-Blind Method; Yohimbine | 1998 |
Ibuprofen plus caffeine in the treatment of tension-type headache.
Topics: Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Tension-Type Headache | 2000 |
The use of ibuprofen plus caffeine to treat tension-type headache.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Research Design; Tension-Type Headache; Time Factors | 2001 |
[Comparative in vitro and in vivo studies on the permeation and penetration of ketoprofen and ibuprofen in human skin].
Topics: Administration, Topical; Adult; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Diffusion Chambers, Culture; Female; Gels; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Permeability; Skin Absorption | 2004 |
Acetaminophen, aspirin, and caffeine in combination versus ibuprofen for acute migraine: results from a multicenter, double-blind, randomized, parallel-group, single-dose, placebo-controlled study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Migraine Disorders | 2006 |
Caffeine as an adjuvant to ibuprofen in treating childhood headaches.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Child; Child, Preschool; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Female; Headache; Humans; Ibuprofen; Male; Pilot Projects; Severity of Illness Index; Treatment Outcome | 2007 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Central Nervous System Stimulants; Codeine; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Prospective Studies; Treatment Outcome | 2008 |
The efficacy of acetaminophen-caffeine compared to Ibuprofen in the control of postoperative pain after periodontal surgery: a crossover pilot study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Chronic Periodontitis; Cross-Over Studies; Debridement; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Periodontal Attachment Loss; Periodontal Diseases; Periodontal Pocket; Pilot Projects; Prospective Studies; Subgingival Curettage; Surgical Flaps; Young Adult | 2009 |
Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Pain Measurement; Pain, Postoperative; Placebos; Pulpectomy; Pulpitis; Root Canal Preparation; Tramadol; Young Adult | 2012 |
A randomized, controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine (Tylenol 3) after outpatient breast surgery.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Breast Neoplasms; Caffeine; Central Nervous System Stimulants; Codeine; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ibuprofen; Middle Aged; Narcotics; Neoplasm Staging; Pain, Postoperative; Postoperative Complications; Prognosis; Prospective Studies; Tertiary Care Centers | 2012 |
Effects of upper respiratory tract illnesses, ibuprofen and caffeine on reaction time and alertness.
Topics: Adolescent; Adult; Affect; Anti-Inflammatory Agents, Non-Steroidal; Attention; Caffeine; Central Nervous System Stimulants; Choice Behavior; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Psychomotor Performance; Reaction Time; Respiratory Tract Diseases; Young Adult | 2014 |
Results of a multicenter, double-blind, randomized, parallel-group, placebo-controlled, single-dose study comparing the fixed combination of acetaminophen, acetylsalicylic acid, and caffeine with ibuprofen for acute treatment of patients with severe migra
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Migraine Disorders | 2014 |
Efficacy and safety of a fixed-dose combination of ibuprofen and caffeine in the management of moderate to severe dental pain after third molar extraction.
Topics: Adolescent; Adult; Analgesics; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Molar, Third; Pain, Postoperative; Tooth Extraction; Treatment Outcome | 2018 |
Effect of Ginger and Novafen on menstrual pain: A cross-over trial.
Topics: Acetaminophen; Adolescent; Adult; Caffeine; Cross-Over Studies; Drug Combinations; Dysmenorrhea; Female; Humans; Ibuprofen; Iran; Plant Preparations; Statistics, Nonparametric; Visual Analog Scale; Young Adult; Zingiber officinale | 2018 |
Pharmacokinetic Properties of Ibuprofen (IBU) From the Fixed-Dose Combination IBU/Caffeine (400/100 mg; FDC) in Comparison With 400 mg IBU as Acid or Lysinate Under Fasted and Fed Conditions-Data From 2 Single-Center, Single-Dose, Randomized Crossover Stu
Topics: Adult; Area Under Curve; Caffeine; Cross-Over Studies; Fasting; Female; Food; Food-Drug Interactions; Healthy Volunteers; Humans; Ibuprofen; Lysine; Male; Middle Aged; Postprandial Period; Young Adult | 2019 |
Preterm Physiologically Based Pharmacokinetic Model. Part II: Applications of the Model to Predict Drug Pharmacokinetics in the Preterm Population.
Topics: Administration, Intravenous; Administration, Oral; Alfentanil; Anti-Bacterial Agents; Caffeine; Computer Simulation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Female; Gentamicins; Gestational Age; Humans; Hypnotics and Sedatives; Ibuprofen; Infant, Newborn; Kidney; Liver; Male; Metabolic Clearance Rate; Midazolam; Models, Biological; Narcotics; Predictive Value of Tests; Premature Birth; Vancomycin | 2020 |
The Impact of Baseline Pain Intensity on the Analgesic Efficacy of Ibuprofen/Caffeine in Patients with Acute Postoperative Dental Pain: Post Hoc Subgroup Analysis of a Randomised Controlled Trial.
Topics: Acute Pain; Adolescent; Adult; Analgesics; Caffeine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Ibuprofen; Male; Pain Management; Pain, Postoperative; Tooth, Impacted; Young Adult | 2020 |
Lack of Evidence for Blood Pressure Effects of Caffeine Added to Ibuprofen.
Topics: Analgesics, Non-Narcotic; Blood Pressure; Caffeine; Double-Blind Method; Humans; Ibuprofen; Pain; Pain, Postoperative | 2023 |
103 other study(ies) available for caffeine and ibuprofen
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
[Ibuprofen pre- and postoperatively in oral surgery].
Topics: Adolescent; Adult; Aged; Aspirin; Caffeine; Codeine; Drug Combinations; Drug Evaluation; Female; Humans; Ibuprofen; Male; Middle Aged; Oral Surgical Procedures, Preprosthetic; Placebos; Postoperative Care; Preoperative Care; Random Allocation; Tooth Extraction | 1986 |
Impact of over the counter availability of non-steroidal anti-inflammatory drugs.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Caffeine; Codeine; Humans; Ibuprofen; Nonprescription Drugs; United States | 1985 |
Dependence on Midol.
Topics: Adult; Aspirin; Caffeine; Drug Combinations; Ephedrine; Female; Humans; Phenacetin; Substance-Related Disorders | 1982 |
[A fatal case due to intoxication with seven drugs detected by GC-MS and TDx methods].
Topics: Acetaminophen; Adult; Bromisovalum; Caffeine; Drug Overdose; Female; Fluorescent Antibody Technique; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; Salicylamides; Suicide; Urea | 1993 |
Premature babies and pharmacology.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Drug Combinations; Humans; Ibuprofen; Infant, Newborn; Infant, Premature; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pharmacology; Prilocaine | 1995 |
Interaction of ibuprofen and indomethacin with caffeine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Chemical Phenomena; Chemistry, Physical; Ibuprofen; Indomethacin; Male; Rats; Skin Absorption; Solubility; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1996 |
Changes in formalin-evoked spinal Fos expression and nociceptive behaviour after oral administration of Bufferin A (aspirin) and L-5409709 (ibuprofen + caffeine + paracetamol).
Topics: Acetaminophen; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Drug Combinations; Formaldehyde; Ibuprofen; Immunohistochemistry; Male; Nociceptors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord | 1997 |
Effect of caffeine on ibuprofen-induced gastric mucosal damage in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Dinoprostone; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Gastrointestinal Motility; Hydrochloric Acid; Ibuprofen; Male; Peroxidase; Rats; Rats, Inbred Strains; Regional Blood Flow; Stomach; Stomach Diseases; Time Factors | 1999 |
Is the combination of ibuprofen and caffeine effective for the treatment of a tension-type headache?
Topics: Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Drug Therapy, Combination; Ibuprofen; Randomized Controlled Trials as Topic; Tension-Type Headache; Treatment Outcome | 2001 |
Inhibitors of arachidonic acid metabolism have variable effects on calcium signaling pathways.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Caffeine; Calcium; Calcium Signaling; Cells, Cultured; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Ibuprofen; Lipoxygenase Inhibitors; Male; Muscle, Smooth, Vascular; Oxazines; Rats; Ryanodine | 2001 |
Migraine sufferers are not seeking nor receiving guideline-based care.
Topics: Acetaminophen; Analgesics; Barbiturates; Caffeine; Drug Combinations; Drug Prescriptions; Female; Health Behavior; Humans; Ibuprofen; Male; Migraine Disorders; Nonprescription Drugs; Office Visits; Patient Satisfaction; Practice Guidelines as Topic; United States | 2002 |
Interaction of ibuprofen and probenecid with drug metabolizing enzyme phenotyping procedures using caffeine as the probe drug.
Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Drug Interactions; Female; Humans; Ibuprofen; Male; Phenotype; Probenecid; Uricosuric Agents | 2003 |
Determination of selected pharmaceuticals and caffeine in sewage and seawater from Tromsø/Norway with emphasis on ibuprofen and its metabolites.
Topics: Caffeine; Chromatography, Liquid; DEET; Gas Chromatography-Mass Spectrometry; Ibuprofen; Norway; Pharmaceutical Preparations; Seawater; Sewage; Triclosan; Water Pollutants, Chemical | 2004 |
Tracking acidic pharmaceuticals, caffeine, and triclosan through the wastewater treatment process.
Topics: Caffeine; Diclofenac; Ibuprofen; Ketoprofen; Meclofenamic Acid; Models, Chemical; Naproxen; Pharmaceutical Preparations; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Glomerular tip lesion associated with nonsteroidal anti-inflammatory drug-induced nephrotic syndrome.
Topics: Accidents, Traffic; Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Barbiturates; Caffeine; Drug Therapy, Combination; Female; Foam Cells; Humans; Ibuprofen; Kidney Glomerulus; Nephrosis, Lipoid; Nephrotic Syndrome; Pain; Tramadol | 2005 |
Effects of selected pharmaceuticals on riverine biofilm communities.
Topics: Bacteria; Biofilms; Bioreactors; Caffeine; Carbamazepine; Carbon Isotopes; Colony Count, Microbial; Drug Prescriptions; Ecosystem; Furosemide; Ibuprofen; In Situ Hybridization, Fluorescence; Microscopy, Confocal; Pharmaceutical Preparations; Rivers | 2005 |
Serum sickness-like reaction to Pamabrom.
Topics: Adult; Arm; Aspirin; Caffeine; Diagnosis, Differential; Drug Combinations; Ephedrine; Female; Humans; Leg; Phenacetin; Propanolamines; Serum Sickness; Theophylline | 2006 |
Effects of pharmaceutical products and municipal wastewaters on temperature-dependent mitochondrial electron transport activity in Elliptio complanata mussels.
Topics: Bivalvia; Caffeine; Carbamazepine; Cholestanol; Cotinine; Electron Transport; Fluoxetine; Ibuprofen; Lipid Peroxidation; Mitochondria; Novobiocin; Pharmaceutical Preparations; Sewage; Temperature; Trimethoprim; Xenobiotics | 2006 |
Hydrogen bonding effects on infrared and Raman spectra of drug molecules.
Topics: Aspirin; Caffeine; Hydrogen Bonding; Ibuprofen; Models, Molecular; Molecular Structure; Spectrum Analysis, Raman | 2007 |
Enhancement of antinociception by co-administration of ibuprofen and caffeine in arthritic rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ibuprofen; Male; Rats; Rats, Wistar; Time Factors | 2006 |
Smoking, caffeine, and nonsteroidal anti-inflammatory drugs in families with Parkinson disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Beverages; Caffeine; Case-Control Studies; Family Health; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Odds Ratio; Parkinson Disease; Risk Factors; Smoking; Tea | 2007 |
A linear scaling study of solvent-solute interaction energy of drug molecules in aqua solution.
Topics: Aspirin; Caffeine; Electrons; Ibuprofen; Mathematical Computing; Pharmaceutical Preparations; Solvents; Thermodynamics; Water | 2007 |
Simultaneous spectrophotometric determination of paracetamol, ibuprofen and caffeine in pharmaceuticals by chemometric methods.
Topics: Acetaminophen; Algorithms; Caffeine; Calibration; Chemistry Techniques, Analytical; Ibuprofen; Least-Squares Analysis; Multivariate Analysis; Neural Networks, Computer; Pharmaceutical Preparations; Spectrophotometry | 2008 |
Investigation of the permeation of model formulations and a commercial ibuprofen formulation in Carbosil and human skin using ATR-FTIR and multivariate spectral analysis.
Topics: Aged; Caffeine; Diffusion; Ethanol; Excipients; Factor Analysis, Statistical; Female; Humans; Ibuprofen; In Vitro Techniques; Membranes, Artificial; Middle Aged; Parabens; Permeability; Reproducibility of Results; Skin Absorption; Solubility; Spectroscopy, Fourier Transform Infrared; Water | 2009 |
Patterns of medication use by chronic and episodic headache sufferers in the general population: results from the frequent headache epidemiology study.
Topics: Adolescent; Adult; Aged; Analgesics; Aspirin; Caffeine; Chronic Disease; Disease Progression; Female; Headache Disorders; Headache Disorders, Secondary; Health Surveys; Humans; Ibuprofen; Male; Middle Aged; Nonprescription Drugs; Tryptamines; Young Adult | 2010 |
Profound hypokalaemia due to Nurofen Plus and Red Bull misuse.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Beverages; Caffeine; Codeine; Drug Combinations; Humans; Hypokalemia; Ibuprofen; Male; Nonprescription Drugs; Rhabdomyolysis; Substance-Related Disorders | 2010 |
A combined desorption ionization by charge exchange (DICE) and desorption electrospray ionization (DESI) source for mass spectrometry.
Topics: Acetaminophen; Caffeine; Ibuprofen; Pharmaceutical Preparations; Pressure; Spectrometry, Mass, Electrospray Ionization | 2011 |
Flip-back, an old trick to face highly contrasted relaxation times: application in the characterization of pharmaceutical mixtures by CPMAS NMR.
Topics: Caffeine; Ibuprofen; Kinetics; Magnetic Phenomena; Magnetic Resonance Spectroscopy; Pharmaceutical Preparations; Time Factors | 2011 |
A new vesicle-loaded hydrogel system suitable for topical applications: preparation and characterization.
Topics: Administration, Topical; Caffeine; Cholesterol; Diffusion; Drug Compounding; Drug Delivery Systems; Fluoresceins; Gels; Humans; Hydrogels; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Liposomes; Models, Chemical; Oxazines; Particle Size; Pharmacokinetics; Polysorbates; Surface-Active Agents | 2011 |
Assessment of the lateral diffusion and penetration of topically applied drugs in humans using a novel concentric tape stripping design.
Topics: Adhesives; Administration, Topical; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Caffeine; Central Nervous System Stimulants; Drug Delivery Systems; Epidermis; Female; Humans; Hydrocortisone; Ibuprofen; Male; Skin Absorption; Young Adult | 2012 |
Batch versus continuous feeding strategies for pharmaceutical removal by subsurface flow constructed wetland.
Topics: Biodegradation, Environmental; Caffeine; Carbamazepine; Clofibric Acid; Diclofenac; Ibuprofen; Ketoprofen; Kinetics; Pharmaceutical Preparations; Waste Disposal, Fluid; Water Movements; Water Pollutants, Chemical; Wetlands | 2012 |
Human pharmaceuticals in wastewaters from urbanized areas of Argentina.
Topics: Argentina; Atenolol; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Cities; Diclofenac; Environmental Monitoring; Humans; Ibuprofen; Mass Spectrometry; Pharmaceutical Preparations; Wastewater; Water Pollutants, Chemical | 2013 |
Dissolution of tablet-in-tablet formulations studied with ATR-FTIR spectroscopic imaging.
Topics: Caffeine; Cellulose; Delayed-Action Preparations; Glucose; Hydrogen-Ion Concentration; Hypromellose Derivatives; Ibuprofen; Methylcellulose; Polyethylene Glycols; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets | 2013 |
Molecular insight into affinities of drugs and their metabolites to lipid bilayers.
Topics: Caffeine; Cell Membrane; Chlorzoxazone; Coumarins; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Ibuprofen; Lipid Bilayers; Molecular Dynamics Simulation; Pharmaceutical Preparations; Phosphatidylcholines; Phosphatidylglycerols; Thermodynamics; Xenobiotics | 2013 |
Skin penetration enhancing properties of the plant N-alkylamide spilanthol.
Topics: Aflatoxin B1; Amides; Caffeine; Female; Humans; Ibuprofen; In Vitro Techniques; Middle Aged; Polyunsaturated Alkamides; Skin; Skin Absorption; T-2 Toxin; Testosterone | 2013 |
Uptake and depuration of pharmaceuticals in reclaimed water by mosquito fish (Gambusia holbrooki): a worst-case, multiple-exposure scenario.
Topics: Animals; Caffeine; Carbamazepine; Cyprinodontiformes; Diphenhydramine; Fresh Water; Ibuprofen; Pharmaceutical Preparations; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2013 |
Ambient desorption/ionization mass spectrometry using a liquid sampling-atmospheric glow discharge (LS-APGD) ionization source.
Topics: Analgesics, Non-Narcotic; Atmospheric Pressure; Caffeine; Coffee; Electrolytes; Equipment Design; Ibuprofen; Ions; Limit of Detection; Mass Spectrometry; Nicotiana; Plant Leaves; Tea | 2013 |
Levetiracetam interacts synergistically with nonsteroidal analgesics and caffeine to produce antihyperalgesia in rats.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Celecoxib; Drug Synergism; Drug Therapy, Combination; Hyperalgesia; Ibuprofen; Inflammation; Levetiracetam; Male; Piracetam; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2013 |
Hot-melt granulation in a twin screw extruder: effects of processing on formulations with caffeine and Ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Drug Compounding; Drug Stability; Hot Temperature; Ibuprofen; Lactose; Particle Size; Solubility; X-Ray Diffraction | 2013 |
Precision criteria to derive sample size when designing pediatric pharmacokinetic studies: which measure of variability should be used?
Topics: Adult; Area Under Curve; Biomedical Research; Caffeine; Child; Child, Preschool; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Itraconazole; Male; Midazolam; Models, Biological; Pharmacokinetics; Sample Size; Theophylline | 2014 |
Using lysosomal membrane stability of haemocytes in Ruditapes philippinarum as a biomarker of cellular stress to assess contamination by caffeine, ibuprofen, carbamazepine and novobiocin.
Topics: Animals; Biomarkers; Bivalvia; Caffeine; Carbamazepine; Hemocytes; Ibuprofen; Lysosomes; Neutral Red; Novobiocin; Wastewater; Water Pollutants, Chemical | 2013 |
The influence of the acyl chain on the transdermal penetration-enhancing effect of synthetic phytoceramides.
Topics: Aged; Caffeine; Ceramides; Female; Humans; Ibuprofen; In Vitro Techniques; Middle Aged; Molecular Structure; Permeability; Skin; Skin Absorption; Sphingosine; Testosterone | 2015 |
Zone fluidics for measurement of octanol-water partition coefficient of drugs.
Topics: 1-Octanol; Acetaminophen; Aniline Compounds; Caffeine; Equipment Design; Ibuprofen; Imidazoles; Riboflavin; Water | 2015 |
Simultaneous determination of caffeine, paracetamol, and ibuprofen in pharmaceutical formulations by high-performance liquid chromatography with UV detection and by capillary electrophoresis with conductivity detection.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Ibuprofen; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet | 2015 |
Yes, caffeine, ibuprofen, carbamazepine, novobiocin and tamoxifen have an effect on Corbicula fluminea (Müller, 1774).
Topics: Animals; Biomarkers; Caffeine; Carbamazepine; Corbicula; DNA Damage; Environmental Monitoring; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Ibuprofen; Lipid Peroxidation; Novobiocin; Oxidative Stress; Tamoxifen; Toxicity Tests; Water Pollutants, Chemical | 2015 |
General stress, detoxification pathways, neurotoxicity and genotoxicity evaluated in Ruditapes philippinarum exposed to human pharmaceuticals.
Topics: Acetylcholinesterase; Animals; Biomarkers; Bivalvia; Caffeine; Carbamazepine; Cytochrome P-450 CYP1A1; DNA Damage; Gastrointestinal Tract; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hemolymph; Ibuprofen; Inactivation, Metabolic; Lipid Peroxidation; Novobiocin; Oxidative Stress; Water Pollutants, Chemical | 2016 |
The effectiveness of a single dose of oral ibuprofen plus caffeine in acute postoperative pain in adults.
Topics: Acute Pain; Analgesics, Non-Narcotic; Caffeine; Humans; Ibuprofen; Pain, Postoperative | 2016 |
Transport behavior of the pharmaceutical compounds carbamazepine, sulfamethoxazole, gemfibrozil, ibuprofen, and naproxen, and the lifestyle drug caffeine, in saturated laboratory columns.
Topics: Caffeine; Carbamazepine; Filtration; Gemfibrozil; Ibuprofen; Naproxen; Ontario; Silicon Dioxide; Sulfamethoxazole; Water Pollutants, Chemical | 2017 |
Decreased alertness due to sleep loss increases pain sensitivity in mice.
Topics: Acute Disease; Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Caffeine; Chronic Disease; Corticosterone; Electroencephalography; Electromyography; Female; Hyperalgesia; Ibuprofen; Male; Mice; Modafinil; Morphine; Pain; Pain Threshold; Sleep Deprivation; Wakefulness; Wakefulness-Promoting Agents | 2017 |
Effect of hydrophobicity of pharmaceuticals and personal care products for adsorption on activated carbon: Adsorption isotherms, kinetics and mechanism.
Topics: Adsorption; Caffeine; Charcoal; Diffusion; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Kinetics; Triclosan; Wastewater; Water; Water Pollutants, Chemical; Water Purification | 2018 |
The effects of human drugs in Corbicula fluminea. Assessment of neurotoxicity, inflammation, gametogenic activity, and energy status.
Topics: Animals; Biomarkers; Caffeine; Carbamazepine; Corbicula; Energy Metabolism; Germ Cells; Humans; Ibuprofen; Inflammation; Neurotoxins; Novobiocin; Tamoxifen; Water Pollutants, Chemical | 2018 |
Regional variation in percutaneous absorption in the tree frog Litoria caerulea.
Topics: Animals; Anura; Benzoic Acid; Caffeine; Ibuprofen; Models, Biological; Skin; Skin Absorption; Xenobiotics | 2018 |
Contaminants of Emerging Concern in Wastewaters in Barbados, West Indies.
Topics: 3,4-Methylenedioxyamphetamine; Androstenedione; Barbados; Caffeine; Chromatography, Liquid; Cocaine; Environmental Monitoring; Estrone; Ibuprofen; N-Methyl-3,4-methylenedioxyamphetamine; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2018 |
Gluing Pills Technology: A novel route to multilayer tablet manufacturing.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Drug Combinations; Elasticity; Excipients; Gelatin; Ibuprofen; Porosity; Povidone; Tablets; Technology, Pharmaceutical; Tensile Strength | 2018 |
Effects of skin region and relative lipophilicity on percutaneous absorption in the toad Rhinella marina.
Topics: Animals; Benzoic Acid; Bufo marinus; Caffeine; Ecosystem; Ibuprofen; In Vitro Techniques; Kinetics; Male; Skin; Skin Absorption; Time Factors; Xenobiotics | 2019 |
Multivariate approaches for the development of quality control in-situ fiber optics dissolution methods for fixed-dose combination tablets.
Topics: Aspirin; Caffeine; Calibration; Chemistry, Pharmaceutical; Drug Combinations; Drug Liberation; Ephedrine; Excipients; Fiber Optic Technology; Guidelines as Topic; Least-Squares Analysis; Phenacetin; Quality Control; Solubility; Tablets; Technology, Pharmaceutical | 2019 |
Selective modification of skin barrier lipids.
Topics: Acetone; Administration, Cutaneous; Animals; Caffeine; Epidermis; Ibuprofen; Lipid Metabolism; Lipids; Models, Animal; Permeability; Solvents; Spectroscopy, Fourier Transform Infrared; Sus scrofa; Water Loss, Insensible | 2019 |
Commercial Screen-Printed Electrodes Based on Carbon Nanomaterials for a Fast and Cost-Effective Voltammetric Determination of Paracetamol, Ibuprofen and Caffeine in Water Samples.
Topics: Acetaminophen; Caffeine; Electrochemistry; Electrodes; Ibuprofen; Limit of Detection; Nanostructures; Nanotubes, Carbon; Reproducibility of Results; Wastewater; Water Pollutants, Chemical | 2019 |
Percutaneous absorption between frog species: Variability in skin may influence delivery of therapeutics.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Anura; Benzoic Acid; Caffeine; Central Nervous System Stimulants; Ibuprofen; Permeability; Skin; Skin Absorption; Species Specificity | 2020 |
Single-Dose Oral Ibuprofen Plus Caffeine for Acute Postoperative Pain in Adults.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Female; Humans; Ibuprofen; Male; Pain, Postoperative | 2020 |
Topical Drug Delivery Systems Based on Bacterial Nanocellulose: Accelerated Stability Testing.
Topics: Administration, Topical; Bacteria; Biocompatible Materials; Caffeine; Cellulose; Diclofenac; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Stability; Humans; Ibuprofen; Lidocaine; Nanoparticles | 2020 |
Can models of percutaneous absorption based on in vitro data in frogs predict in vivo absorption?
Topics: Animals; Benzoic Acid; Bufo marinus; Caffeine; Cell Membrane Permeability; Diffusion; Ibuprofen; In Vitro Techniques; Male; Models, Biological; Skin; Skin Absorption | 2020 |
The effect of ibuprofen and caffeine prophylaxis on retinopathy of prematurity.
Topics: Birth Weight; Caffeine; Gestational Age; Humans; Ibuprofen; Infant, Newborn; Infant, Very Low Birth Weight; Retinopathy of Prematurity; Retrospective Studies; Risk Factors; Vascular Endothelial Growth Factor A | 2021 |
Pharmaceuticals and other contaminants of emerging concern in Admiralty Bay as a result of untreated wastewater discharge: Status and possible environmental consequences.
Topics: Caffeine; Cosmetics; Diclofenac; Environmental Monitoring; Humans; Ibuprofen; Ketoconazole; Pharmaceutical Preparations; Wastewater; Water Pollutants, Chemical | 2022 |
Simultaneous Determination of Paracetamol, Ibuprofen, and Caffeine in Tablets by Molecular Absorption Spectroscopy Combined with Classical Least Square Method.
Topics: Acetaminophen; Caffeine; Ibuprofen; Least-Squares Analysis; Reproducibility of Results; Spectrophotometry; Tablets | 2022 |
Tracing the influence of caffeine on the pharmacokinetic parameters of three headache relieving pharmaceuticals applying synchronous fluorescence spectroscopy.
Topics: Caffeine; Headache; Humans; Ibuprofen; Micelles; Spectrometry, Fluorescence | 2022 |
Removal of pharmaceuticals by vertical flow constructed wetland with different configurations: Effect of inlet load and biochar addition in the substrate.
Topics: Amoxicillin; Bays; Caffeine; Charcoal; Ibuprofen; Nitrogen; Pharmaceutical Preparations; Waste Disposal, Fluid; Wastewater; Wetlands | 2022 |
Fecal indicator bacteria levels at a marine beach before, during, and after the COVID-19 shutdown period and associations with decomposing seaweed and human presence.
Topics: Acetaminophen; Animals; Bacteria; Bathing Beaches; Caffeine; COVID-19; Dogs; Enterococcus; Environmental Monitoring; Feces; Humans; Ibuprofen; Naproxen; Seaweed; Water; Water Microbiology | 2022 |
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin Gene-Related Peptide Receptor Antagonists; Child; Diclofenac; Female; Headache; Humans; Ibuprofen; Migraine Disorders; Morphine Derivatives; Naproxen; Nasal Sprays; Pregnancy; Prochlorperazine; Taiwan; Tramadol; Tryptamines | 2022 |
Ibuprofen as an Organic Pollutant in the Danube and Effects on Aquatic Organisms.
Topics: Aquatic Organisms; Caffeine; Chromatography, Liquid; Humans; Ibuprofen; Water Pollutants, Chemical | 2023 |
Analyzing microbial communities and their biodegradation of multiple pharmaceuticals in membrane bioreactors.
Topics: Acetaminophen; Atenolol; Biodegradation, Environmental; Bioreactors; Caffeine; Environmental Pollutants; Ibuprofen; Microbiota; Pharmaceutical Preparations; RNA, Ribosomal, 16S; Water Pollutants, Chemical | 2023 |
Occurrence and risk assessment of pharmaceuticals in hospital wastewater in Costa Rica.
Topics: Acetaminophen; Anti-Bacterial Agents; Caffeine; Costa Rica; Environmental Monitoring; Hospitals; Ibuprofen; Pharmaceutical Preparations; Risk Assessment; Wastewater; Water Pollutants, Chemical | 2023 |
MOF-Thermogel Composites for Differentiated and Sustained Dual Drug Delivery.
Topics: Caffeine; Drug Therapy, Combination; Ibuprofen; Leprostatic Agents | 2023 |
Occurrence of contaminants of emerging concern and pesticides and relative risk assessment in Tunisian groundwater.
Topics: Caffeine; Environmental Monitoring; Groundwater; Ibuprofen; Pesticides; Risk Assessment; Tunisia; Water Pollutants, Chemical | 2024 |
On-farm Occurrence of Pharmaceuticals and Their Environmental Hazard: Case Study of a Tropical Dairy farm.
Topics: Acetaminophen; Animals; Caffeine; Carbamazepine; Environmental Monitoring; Farms; Ibuprofen; Ketoprofen; Pharmaceutical Preparations; Risperidone; Wastewater; Water; Water Pollutants, Chemical | 2023 |
Legal Performance-enhancing Drugs Alter Course and Treatment of Rhabdomyolysis-induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Animals; Caffeine; Cilastatin; Glycerol; Humans; Ibuprofen; Mice; Performance-Enhancing Substances; Rhabdomyolysis | 2023 |