caffeine and hypericum

caffeine has been researched along with hypericum in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gorski, JC; Hall, SD; Hamman, MA; Huang, SM; Lesko, LJ; Wang, Z1
Krähenbühl, S; Todesco, L; Wenk, M1
Abd El-Aty, AM; An, W; Chen, GL; Li, Q; Li, Z; Liu, J; Tang, ZR; Wang, D; Wang, LS; Wu, J; Zhou, G; Zhou, HH; Zhu, B1
Arold, G; Bauer, S; Diefenbach, K; Donath, F; Friede, M; Henneicke-von Zepelin, HH; Maurer, A; Roots, I1
Ang, CY; Cui, Y; Gardner, SF; Gentry, WB; Gurley, BJ; Hubbard, MA; Williams, DK1
Coskun, I; Kayir, H; Ozturk, N; Ozturk, Y; Uzbay, IT1

Trials

4 trial(s) available for caffeine and hypericum

ArticleYear
The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity.
    Clinical pharmacology and therapeutics, 2001, Volume: 70, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biological Availability; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dietary Supplements; Drug Interactions; Enzyme Induction; Female; Humans; Hypericum; Injections, Intravenous; Isoenzymes; Male; Midazolam; Oxidoreductases, N-Demethylating; Plant Extracts; Tolbutamide

2001
The influence of St John's Wort on CYP2C19 activity with respect to genotype.
    Journal of clinical pharmacology, 2004, Volume: 44, Issue:6

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Genotype; Humans; Hypericum; Male; Mephenytoin; Mixed Function Oxygenases; Plant Extracts; Polymorphism, Genetic

2004
No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St John's wort extract.
    Planta medica, 2005, Volume: 71, Issue:4

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Area Under Curve; Caffeine; Cardiotonic Agents; Central Nervous System Stimulants; Digoxin; Double-Blind Method; Drug Interactions; Female; Humans; Hypericum; Hypoglycemic Agents; Male; Middle Aged; Phytotherapy; Plant Extracts; Tolbutamide; Treatment Outcome

2005
Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba.
    Drugs & aging, 2005, Volume: 22, Issue:6

    Topics: Administration, Oral; Aged; Allyl Compounds; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dietary Supplements; Drug Administration Schedule; Female; Ginkgo biloba; Herb-Drug Interactions; Humans; Hypericum; Isoenzymes; Male; Midazolam; Panax; Phenotype; Plant Preparations; Sulfides

2005

Other Studies

2 other study(ies) available for caffeine and hypericum

ArticleYear
Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females.
    British journal of clinical pharmacology, 2004, Volume: 57, Issue:4

    Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Humans; Hydrocortisone; Hypericum; Male; Middle Aged; Xanthine Oxidase

2004
Extract of Hypericum perforatum blocks caffeine-induced locomotor activity in mice: a possible role of nitric oxide.
    Phytotherapy research : PTR, 2007, Volume: 21, Issue:5

    Topics: Animals; Arginine; Caffeine; Hypericum; Male; Mice; Motor Activity; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts

2007