caffeine and hexobarbital

caffeine has been researched along with hexobarbital in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199026 (81.25)18.7374
1990's2 (6.25)18.2507
2000's3 (9.38)29.6817
2010's1 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Atkinson, J; Milon, H1
Veselova, TP1
Busch, M; Klapproth, HE; Lücker, PW; Schmitz, H1
Aeschbacher, HU; Atkinson, J; Domahidy, B1
Fukushima, M; Shibata, M1
Gibaldi, M1
Apseloff, G; Gerber, N; Hilliard, JB; Mays, DC1
Gerber, N; Hilliard, JB; Mays, DC; Nawoot, S; Pacula, CM1
Greengard, P; Quinn, GP; Reid, MB1
Kimura, R; Murata, T1
Falk, M; Fürst, W1
Hiskey, CF; Lachman, L; Mayell, JS1
Hach, B; Heim, F1
Hansch, C; Martin, YC1
Nieschulz, O1
Coville, PF; Telford, JM2
Burgison, RM; Dietz, AJ1
Melson, F1
Casadio, S; Coppi, G; Marazziùberti, E; Pala, G1
McMartin, C; Street, HV1
Ristow, W1
Tozhanova, NM; Zakusov, VV1
Kruse, H; Rössner, M; Siegemund, G1
PILZ, G1
JACOB, J; MICHAUD, G1
ARUSHANIAN, EB; SHAPAVALOV, AI1
LECHAT, P; MAGET, E; STREICHENBERGER, G1

Reviews

1 review(s) available for caffeine and hexobarbital

ArticleYear
Drug interactions: Part I.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5

    Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine

1992

Other Studies

31 other study(ies) available for caffeine and hexobarbital

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Hexobarbital blood levels and effects on EEG in the presence and absence of caffeine.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:11

    Topics: Animals; Body Temperature; Caffeine; Carbon Dioxide; Drug Interactions; Electroencephalography; Hexobarbital; Kinetics; Male; Rats; Time Factors

1979
[Pharmacological characteristics of nilverm].
    Veterinariia, 1979, Issue:5

    Topics: Animals; Caffeine; Cardiovascular System; Cats; Central Nervous System; Digestive System; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Hexobarbital; Levamisole; Mice; Sheep; Tetramisole

1979
[A novel psychometric test model applying tailored testing for economic and efficient collection of psychopharmacological effects (author's transl)].
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:5

    Topics: Attention; Caffeine; Female; Hexobarbital; Humans; Male; Memory; Models, Psychological; Motor Skills; Pemoline; Placebos; Psychometrics; Psychopharmacology; Stress, Psychological

1979
The effect of caffeine on barbiturate sleeping time and brain level.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:3

    Topics: Aminopyrine N-Demethylase; Analysis of Variance; Animals; Barbiturates; Brain Chemistry; Caffeine; Drug Interactions; Hexobarbital; Liver; Male; Morphine Derivatives; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Sleep; Time Factors

1975
[Acute toxicity and sedative action of zizyphus seeds (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1975, Volume: 95, Issue:4

    Topics: Anesthesia, Intravenous; Animals; Caffeine; Chlorpromazine; Drug Evaluation, Preclinical; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Mice; Plant Extracts; Seeds

1975
Inhibition and induction of drug metabolism by psoralens: alterations in duration of sleep induced by hexobarbital and in clearance of caffeine and hexobarbital in mice.
    Xenobiotica; the fate of foreign compounds in biological systems, 1991, Volume: 21, Issue:11

    Topics: Animals; Caffeine; Coumarins; Furocoumarins; Half-Life; Hexobarbital; Male; Methoxsalen; Mice; Sleep; Time Factors; Warfarin

1991
Inhibition and induction of drug biotransformation in vivo by 8-methoxypsoralen: studies of caffeine, phenytoin and hexobarbital metabolism in the rat.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Animals; Biotransformation; Caffeine; Hexobarbital; Male; Methoxsalen; Phenytoin; Rats; Rats, Inbred Strains

1987
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
Influence of alkylamides of glutamic acid and related compounds on the central nervous system. I. Central depressant effect of theanine.
    Chemical & pharmaceutical bulletin, 1971, Volume: 19, Issue:6

    Topics: Amides; Amino Acids; Animals; Bemegride; Brain; Brain Chemistry; Caffeine; Carbon Isotopes; Central Nervous System; Depression, Chemical; Glutamine; Hexobarbital; Liver; Male; Mice; Pentylenetetrazole; Picrotoxin; Piperidines; Seizures; Sleep; Strychnine

1971
[Drug permeation through synthetic lipid membranes. Permeability of lecithin-collodium membranes for drugs and metabolites].
    Die Pharmazie, 1974, Volume: 29, Issue:9

    Topics: Buffers; Caffeine; Diffusion; Hexobarbital; Hydrogen-Ion Concentration; Kinetics; Membranes, Artificial; Models, Chemical; Papaverine; Phenobarbital; Phenytoin; Phosphatidylcholines; Quinine; Salicylates; Solutions; Time Factors

1974
Quantitative analysis of a multicomponent drug product using liquid chromatography.
    Analytical chemistry, 1974, Volume: 46, Issue:3

    Topics: Analgesics; Aspirin; Caffeine; Chromatography, Gas; Hexobarbital; Phenacetin; Solvents; Temperature

1974
[Comparative studieson the central stimulating effects of caffeie and chlorogenic acid in white mice].
    Arzneimittel-Forschung, 1971, Volume: 2

    Topics: Animals; Caffeine; Chlorogenic Acid; Drug Antagonism; Hexobarbital; Male; Mice; Movement; Oxygen Consumption; Seizures; Sleep

1971
Influence of hydrophobic character on the relative rate of oxidation of drugs by rat liver microsomes.
    Journal of medicinal chemistry, 1971, Volume: 14, Issue:9

    Topics: Aniline Compounds; Animals; Barbiturates; Caffeine; Chemical Phenomena; Chemistry, Physical; Chlorine; Codeine; Ephedrine; Fatty Alcohols; Hexobarbital; Kinetics; Male; Mathematics; Microsomes, Liver; Mixed Function Oxygenases; Naphthalenes; Oxidoreductases; Phenobarbital; Physostigmine; Rats; Solubility; Structure-Activity Relationship

1971
[Pharmacology of the active substances in betel. 3. Experiments with arecaidine].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:2

    Topics: Animals; Areca; Behavior, Animal; Bile; Blood Glucose; Blood Pressure; Caffeine; Chlorpromazine; Depression, Chemical; Diuresis; Dogs; Drug Synergism; Efficiency; Glutamates; Hexobarbital; Imipramine; Learning; Mice; Nicotinic Acids; Parasympathomimetics; Perception; Phenothiazines; Plant Extracts; Plants, Medicinal; Psychopharmacology; Rats; Reserpine; Stimulation, Chemical

1970
The effect of thyroid hormones on the action of some centrally acting drugs.
    British journal of pharmacology, 1970, Volume: 40, Issue:4

    Topics: Analgesia; Animals; Caffeine; Castration; Dextroamphetamine; Drug Synergism; Ethinyl Estradiol; Hexobarbital; Male; Mice; Morphine; Motor Activity; Rats; Sex Factors; Sleep; Thyroidectomy; Thyroxine; Time Factors

1970
The hypnotic properties of 8-ethylthio-6-thiotheophylline sodium.
    Toxicology and applied pharmacology, 1968, Volume: 12, Issue:2

    Topics: Amphetamine; Animals; Caffeine; Chloral Hydrate; Chlorpromazine; Dogs; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Meprobamate; Methylphenidate; Mice; Morphine; Nalorphine; Nikethamide; Pentobarbital; Pentylenetetrazole; Phenobarbital; Rabbits; Rats; Reserpine; Sleep; Theophylline; Thiopental

1968
Alteration of the flicker fusion frequency and auditory thresholds in man by Frenolon and Trioxazine compared with other centrally acting compounds.
    Therapia Hungarica (English edition), 1968, Volume: 16, Issue:3

    Topics: Auditory Threshold; Caffeine; Dioxoles; Flicker Fusion; Hexobarbital; Humans; Meprobamate; Methods; Morpholines; Pentylenetetrazole; Tranquilizing Agents

1968
Changes in drug sensitivity in hyperthyroidism.
    British journal of pharmacology, 1969, Volume: 36, Issue:1

    Topics: Animals; Brain; Caffeine; Calcium; Dextroamphetamine; Female; Hexobarbital; Hyperthyroidism; Rats; Thyroxine; Uterus

1969
Influence on central nervous system of 39p-propionyl-o-methoxy-phenoxy)-1,2-propanediol.
    Experientia, 1964, Aug-15, Volume: 20, Issue:8

    Topics: Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Caffeine; Central Nervous System; Cocaine; Hexobarbital; Mephenesin; Pentylenetetrazole; Propylene Glycols; Rabbits; Rats; Strychnine

1964
Gas-liquid chromatography of submicrogram amounts of drugs. II. Analysis of barbiturates and related drugs in biological media.
    Journal of chromatography, 1966, Volume: 23, Issue:2

    Topics: Amobarbital; Aspirin; Barbiturates; Bemegride; Caffeine; Chromatography, Gas; Glutethimide; Hexobarbital; Humans; Liver Extracts; Pentobarbital; Salicylates; Secobarbital

1966
[Successful treatment of objective clocking tinnitus].
    Zeitschrift fur Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete, 1966, Volume: 45, Issue:2

    Topics: Caffeine; Craniocerebral Trauma; Delayed-Action Preparations; Hexobarbital; Humans; Injections, Intravenous; Procaine; Tinnitus; Tympanic Membrane

1966
[Combined action of caffeine and sydnocarb].
    Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 96, Issue:8

    Topics: Animals; Blood Pressure; Caffeine; Central Nervous System Stimulants; Conditioning, Classical; Drug Synergism; Hexobarbital; Lethal Dose 50; Mice; Motor Activity; Oxadiazoles; Rabbits; Rats; Sydnones

1983
Thyroliberin (thyrotropin releasing hormone): antagonism of halothane and hexobarbital narcosis in mice. Comparison with pentetrazol, caffeine, d-amphetamine and adrenaline.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:3

    Topics: Animals; Caffeine; Dextroamphetamine; Dose-Response Relationship, Drug; Epinephrine; Halothane; Hexobarbital; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Thyrotropin-Releasing Hormone

1982
[Ambulatory anesthesia in dentistry, brief anesthesia by evipal-sodium; use of the analeptic camphor-caffeine].
    Zahnarztliche Welt, 1952, Aug-10, Volume: 7, Issue:15

    Topics: Anesthesia; Anesthesiology; Caffeine; Camphor; Central Nervous System Stimulants; Dentistry; Hexobarbital; Sodium

1952
[The effect of various pharmacological agents (amphetamine, cocaine, caffeine, hexobarbital, meprobamate, morphine, dextromoramide, 1-methadone, pethidine and CT 3570) on the time of exhaustion and behavior of animals swimming at 20 degrees C].
    Medicina experimentalis : International journal of experimental medicine, 1960, Volume: 2

    Topics: Amphetamine; Amphetamines; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior; Caffeine; Central Nervous System Stimulants; Cocaine; Dextromoramide; Hexobarbital; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed

1960
[EFFECT OF STIMULANTS AND DEPRESSANTS ON THE ACTIVITY OF SINGLE NEURONS OF THE SPINAL CORD FOLLOWING CEREBELLAR STIMULATION].
    Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57

    Topics: Brain; Caffeine; Cats; Cerebellum; Electric Stimulation; Electrophysiology; Hexobarbital; Neurons; Pentobarbital; Pentylenetetrazole; Pharmacology; Piperidines; Research; Spinal Cord; Spinal Nerves; Urethane

1964
[PHARMACOLOGIC STUDY OF RETURN TO SLEEP INDUCED IN THE RAT BY SUDDEN CHANGE IN ENVIRONMENTAL TEMPERATURE].
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1965, Volume: 13

    Topics: Adrenalectomy; Amphetamine; Amphetamines; Caffeine; Chloral Hydrate; Cocaine; Dihydroergotoxine; Ergot Alkaloids; Hexobarbital; Hypnotics and Sedatives; Iproniazid; Pentobarbital; Pentylenetetrazole; Pharmacology; Pregnanediones; Rats; Research; Reserpine; Sleep; Temperature; Yohimbine

1965