caffeine has been researched along with haloperidol in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (33.33) | 18.7374 |
| 1990's | 13 (14.44) | 18.2507 |
| 2000's | 27 (30.00) | 29.6817 |
| 2010's | 19 (21.11) | 24.3611 |
| 2020's | 1 (1.11) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Blake, JF; Curatolo, WJ; Lombardo, F | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Sen, S; Sinha, N | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A | 1 |
| Boissier, JR; Dumont, C; Oberlander, C; Peterfalvi, M | 1 |
| Andén, NE; Jackson, DM | 1 |
| Dreesen, R; Stüttgen, G | 1 |
| Henry, G; King, DJ | 1 |
| Calder, LD; Karler, R | 1 |
| Hishinuma, S; Hongo, I; Kurokawa, M; Uchida, MK | 1 |
| Rudas, N; Tondo, L | 1 |
| Kuribara, H; Tadokoro, S | 1 |
| Asami, T; Ida, I; Kuribara, H; Machiyama, Y; Tadokoro, S | 1 |
| Caporali, MG; Popoli, P; Scotti de Carolis, A | 1 |
| Fletcher, JE; Lizzo, FH; Rosenberg, H | 1 |
| Hommer, DW; Skirboll, LR; Stoner, GR; Werkman, S | 1 |
| Fujiwara, Y; Kazahaya, Y; Otsuki, S; Sandyk, R; Takeda, T | 1 |
| La Cascia, C; Mascarella, A; Migneco, G; Navetta, A; Tripi, S | 1 |
| Holloway, WR; Thor, DH | 1 |
| Caporali, MG; de Carolis, AS; Popoli, P | 1 |
| Matsubara, S; Omori, T | 1 |
| Kalivas, PW | 1 |
| Zetler, G | 1 |
| Filippova, LM; Rapoport, IA; Zhurkov, VS | 1 |
| Boissier, JR; Larousse, C; Simon, P; Villeneuve, A | 1 |
| Atanassova-Shopova, S; Lazarova, MB; Roussinov, KS | 1 |
| Bass, WC; Brown, H | 1 |
| Ban, TA; Lehmann, HE | 1 |
| Senault, B | 1 |
| De Fina, V; Duzzi, L; Valsecchi, B | 1 |
| Hance, AJ; Monti, JM | 1 |
| Chandra, A; Lin, MT; Liu, GG | 1 |
| Yonkov, DI | 1 |
| Boadle-Biber, MC | 1 |
| Schechter, MD | 1 |
| Jones, RS; Olpe, HR; Steinmann, MW | 1 |
| Ellison, G; Nelson, L; Potthoff, AD | 1 |
| Mueller, K; Nyhan, WL; Palmour, R; Saboda, S | 1 |
| Hirshkowitz, M; Karacan, I; Thornby, JI | 1 |
| Castel, MN; Dagerlind, A; Hökfelt, T; Morino, P | 1 |
| Collins, SP; Mendes, LS | 1 |
| Dalia, A; Uretsky, NJ; Wallace, LJ | 1 |
| Fredholm, BB; Nergårdh, R; Svenningsson, P | 1 |
| Beuckmann, CT; Franke, H; Galla, HJ | 1 |
| Dorsa, DM; Ward, RP | 1 |
| Beilstein, MA; Chen, JF; Cuellar, B; Fink, JS; Grandy, DK; Hackett, E; Impagnatiello, F; Low, MJ; Moratalla, R; Ongini, E; Rubinstein, M; Schwarzschild, MA | 1 |
| Ross, BM; Seeman, M; Turenne, SD | 1 |
| Alvarez-Cervera, FJ; Arankowsky-Sandoval, G; Góngora-Alfaro, JL; Heredia-López, F; Moo-Puc, RE; Pineda, JC | 1 |
| Costentin, J; El Yacoubi, M; Vaugeois, JM | 1 |
| Bishnoi, M; Chopra, K; Kulkarni, SK | 1 |
| Christopher, TA; Gao, F; Huang, Z; Liu, X; Lopez, B; Ma, X; Shi, G; Zhang, Y | 1 |
| Grzelak, ME; Hodgson, RA; Hunter, JC; Parker, EM; Pond, AJ; Varty, GB | 1 |
| Bateup, HS; Gong, S; Greengard, P; Heintz, N; Kuroiwa, M; Nishi, A; Svenningsson, P | 1 |
| Barodia, SK; Luthra, PM; Raghubir, R | 1 |
| Ballero, M; Barhate, S; Kasture, S; Maxia, A; Mohan, M; Sanna, C | 1 |
| Collins, LE; Farrar, AM; Font, L; Nunes, EJ; Patel, V; Sager, TN; Salamone, JD; Schlar, DE | 1 |
| Goode, T; Harris, A; Trevitt, J; Vallance, C | 1 |
| Adams, C; Bilsky, EJ; Cormier, J; Dunbar, C; Mercer, H; Negus, SS; Stevenson, GW | 1 |
| Alvarez-Cervera, FJ; Bata-García, JL; Góngora-Alfaro, JL; Heredia-López, FJ; Moo-Puc, RE; Pineda, JC; Villanueva-Toledo, JR | 1 |
| Eyanagi, R; Imoto, M; Kuroki, H; Nishimura, S; Shimeno, H; Soeda, S; Toda, A; Uchiyama, H; Watanabe, S | 1 |
| Cerimele, JM; Jutras-Aswad, D; Stern, AP | 1 |
| Hawryluck, LA; Kraeva, N; Riazi, S; Russell, T; Steel, AC | 1 |
| Acuña-Lizama, MM; Alvarez-Cervera, FJ; Bata-García, JL; Góngora-Alfaro, JL | 1 |
| Acquas, E; Arote, S; Cotti, E; Gaikar, M; Kasture, SB; Kasture, V; Rosas, M; Salve, B | 1 |
| Engmann, O; Giralt, A; Girault, JA | 1 |
| Ain, R; Drumm, M; Joshi, RS; Panicker, MM; Quadros, R | 1 |
| Avvisati, L; Buonaguro, EF; de Bartolomeis, A; Iasevoli, F; Latte, G; Marmo, F; Tomasetti, C | 1 |
| Anoopkumar-Dukie, S; Arora, D; Grant, GD; Hall, S; Kinra, M; Mallik, SB; Mudgal, J; Nampoothiri, M; Rao, CM | 1 |
1 review(s) available for caffeine and haloperidol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for caffeine and haloperidol
| Article | Year |
|---|---|
The effect of neuroleptics on cognitive and psychomotor function. A preliminary study in healthy volunteers.
Topics: Adult; Antipsychotic Agents; Arousal; Attention; Caffeine; Diazepam; Female; Flicker Fusion; Haloperidol; Humans; Life Change Events; Male; Neuropsychological Tests; Personality Inventory; Problem Solving; Psychomotor Performance; Reaction Time; Sensory Thresholds; Trihexyphenidyl | 1992 |
Effects of psychoactive drugs on conflict avoidance behavior in human subjects.
Topics: Adolescent; Adult; Amobarbital; Avoidance Learning; Caffeine; Child; Chlordiazepoxide; Chlorpromazine; Conflict, Psychological; Electroshock; Female; Haloperidol; Humans; Male; Meprobamate; Methamphetamine; Neurotic Disorders; Pentylenetetrazole; Perphenazine; Placebos; Tranquilizing Agents | 1971 |
87 other study(ies) available for caffeine and haloperidol
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Computation of brain-blood partitioning of organic solutes via free energy calculations.
Topics: Animals; Blood-Brain Barrier; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Membrane Lipids; Microcirculation; Molecular Conformation; Molecular Structure; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Software; Solubility; Thermodynamics | 1996 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines | 2021 |
Pharmacological interactions with circling behaviour induced by the piperidinyl indole derivative RU 23686.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Caffeine; Drug Interactions; Haloperidol; Humans; Indoles; Male; Methyltyrosines; Methysergide; Motor Activity; Neurotransmitter Agents; Nialamide; Phenoxybenzamine; Propranolol; Rats; Reserpine; Scopolamine; Stereotyped Behavior | 1977 |
Locomotor activity stimulation in rats produced by dopamine in the nucleus accumbens: potentiation by caffeine.
Topics: Animals; Caffeine; Dextroamphetamine; Dopamine; Drug Synergism; Haloperidol; Male; Motor Activity; Nialamide; Olfactory Bulb; Rats; Reserpine; Stimulation, Chemical; Time Factors | 1975 |
Dopamine effects on the microcirculation and veins of the skin after local application and their changes by antagonistic drugs.
Topics: Adult; Anesthesia, General; Caffeine; Child; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Guanethidine; Haloperidol; Humans; Infant; Microcirculation; Phentolamine; Skin; Veins | 1979 |
Excitatory amino acids and the actions of cocaine.
Topics: Animals; Caffeine; Cocaine; Dextromethorphan; Dizocilpine Maleate; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism; Stereotyped Behavior | 1992 |
Haloperidol differentiates smooth muscle contractions induced by release of intracellularly stored Ca and by influx of extracellular Ca.
Topics: Animals; Caffeine; Calcium; Carbachol; Female; Guinea Pigs; Haloperidol; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Potassium | 1992 |
The course of a seasonal bipolar disorder influenced by caffeine.
Topics: Bipolar Disorder; Caffeine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Haloperidol; Humans; Lithium; Middle Aged; Recurrence; Seasons | 1991 |
The ambulation-increasing effect of buprenorphine in mice: comparison with the effect of morphine.
Topics: Animals; Buprenorphine; Caffeine; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Locomotion; Male; Methamphetamine; Mice; Morphine; Naloxone; Pilocarpine; Scopolamine | 1991 |
[Characteristics of antagonism between ceruletide and various central-acting drugs: investigation by means of ambulatory activity in mice].
Topics: Animals; Bromocriptine; Caffeine; Ceruletide; Cocaine; Dose-Response Relationship, Drug; Drug Tolerance; Ephedrine; Haloperidol; Male; Methamphetamine; Methylphenidate; Mice; Morphine; Motor Activity; Scopolamine | 1990 |
The role of the purinergic system in the control of stereotypy: relationship to D-1/D-2 dopamine receptor activity.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzazepines; Caffeine; Carbamazepine; Dopamine Antagonists; Drug Interactions; Electroencephalography; Haloperidol; Male; Rabbits; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic; Stereotyped Behavior | 1989 |
Effects of droperidol, haloperidol and ketamine on halothane, succinylcholine and caffeine contractures: implications for malignant hyperthermia.
Topics: Animals; Caffeine; Contracture; Droperidol; Haloperidol; Halothane; Humans; Ketamine; Male; Malignant Hyperthermia; Rats; Rats, Inbred Strains; Succinylcholine | 1989 |
Preferential effects of caffeine on limbic and cortical dopamine systems.
Topics: Animals; Caffeine; Diazepam; Frontal Lobe; Haloperidol; Limbic System; Male; Mesencephalon; Neural Pathways; Neurons; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Synaptic Transmission | 1988 |
Inhibitory effects of carbamazepine on clonidine-induced aggressive behavior in mice.
Topics: Adenosine; Aggression; Animals; Behavior, Animal; Caffeine; Carbamazepine; Clonidine; Haloperidol; Male; Mice; Prazosin; Receptors, Cell Surface; Yohimbine | 1988 |
[Cytolytic episodes during cirrhosis].
Topics: Antipyrine; Anxiety Disorders; Barbiturates; Caffeine; Cholestasis; Drug Therapy, Combination; Female; Haloperidol; Humans; Liver Cirrhosis; Maprotiline; Middle Aged; Recurrence; Temazepam; Time Factors | 1986 |
Interactive effects of caffeine, 2-chloroadenosine and haloperidol on activity, social investigation and play fighting of juvenile rats.
Topics: 2-Chloroadenosine; Adenosine; Aggression; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Humans; Male; Motor Activity; Rats; Receptors, Cell Surface; Receptors, Purinergic; Social Behavior | 1985 |
Is the purinergic system involved in the control of pathological movements?
Topics: Animals; Caffeine; Carbamazepine; Electroencephalography; Haloperidol; Male; Purines; Rabbits; Stereotyped Behavior | 1987 |
Rapid cooling contracture in frog striated muscles treated with chlorpromazine and haloperidol.
Topics: Animals; Caffeine; Chlorpromazine; Cold Temperature; Dantrolene; Haloperidol; Muscle Contraction; Muscles; Procaine; Ranidae; Time Factors; Toes | 1985 |
Sensitization to repeated enkephalin administration into the ventral tegmental area of the rat. II. Involvement of the mesolimbic dopamine system.
Topics: Amphetamine; Animals; Behavior, Animal; Caffeine; Corpus Striatum; Dopamine; Enkephalin, Methionine; Haloperidol; Injections, Intraventricular; Limbic System; Male; Motor Activity; Neurotensin; Nucleus Accumbens; Rats; Rats, Inbred Strains; Tegmentum Mesencephali | 1985 |
Drug-induced catalepsy as influenced by convulsant and anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Arecoline; Bemegride; Caffeine; Catalepsy; Central Nervous System Stimulants; Drug Synergism; Ethosuximide; Haloperidol; Humans; Lobeline; Male; Mice; Mice, Inbred Strains; Nicotine; Nikethamide; Paraoxon; Pentylenetetrazole; Pilocarpine; Tetrabenazine; Tremorine; Trifluoperazine | 1973 |
Investigation of the mutagenic activity of phenothiazines and other drug preparations.
Topics: Animals; Caffeine; Chromosome Aberrations; Drosophila melanogaster; Gene Frequency; Genes, Lethal; Haloperidol; Larva; Mutagens; Mutation; Phenothiazines; Promethazine; Sex Chromosomes; Structure-Activity Relationship | 1973 |
Flurothyl in mice: seizure, post-convulsive behavior, and interactions with psychotropic drugs.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Biperiden; Caffeine; Catalepsy; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Diazepam; Electroshock; Haloperidol; Humans; Imipramine; Iproniazid; Meprobamate; Monoamine Oxidase Inhibitors; Motor Activity; Parasympatholytics; Pargyline; Prenylamine; Procyclidine; Rats; Reflex; Reserpine; Seizures; Tranylcypromine | 1968 |
Experimental study of the effect of lithium, haloperidol, caffeine and theophylline on convulsive seizure reactions.
Topics: Animals; Caffeine; Drug Synergism; Haloperidol; Lithium; Male; Rats; Seizures; Theophylline | 1974 |
Effect of drugs on visually controlled avoidance behavior in rhesus monkeys: a psychophysical analysis.
Topics: Anesthetics; Animals; Avoidance Learning; Caffeine; Chlorpromazine; Dextroamphetamine; Escape Reaction; Hallucinogens; Haloperidol; Haplorhini; Lysergic Acid Diethylamide; Male; Morphine; Parasympatholytics; Pentobarbital; Phencyclidine; Piperidines; Psychopharmacology; Size Perception; Strychnine; Visual Perception | 1967 |
[Intraspecific aggressive behavior induced by apomorphine in the rat].
Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine | 1970 |
[Variations in toxicologic responses of rats in relation to the type of enteric administration].
Topics: Animals; Caffeine; Diet; Haloperidol; Isoniazid; Male; Papaverine; Phenylbutazone; Phenylhydrazines; Phosphoric Acids; Rats; Thiazoles | 1967 |
Effects of haloperidol and trifluperidol on operant behavior in the rat.
Topics: Animals; Antidepressive Agents; Butyrophenones; Caffeine; Conditioning, Operant; Fluorine; Haloperidol; Male; Piperidines; Placebos; Rats; Transfer, Psychology; Trifluperidol | 1967 |
The effects of theophylline and caffeine on thermoregulatory functions of rats at different ambient temperatures.
Topics: Animals; Body Temperature Regulation; Caffeine; Drug Interactions; Haloperidol; Hydroxydopamines; Male; Phentolamine; Propranolol; Rats; Temperature; Theophylline | 1980 |
Possible role of brain dopaminergic systems in the memory effects of central stimulants.
Topics: Amphetamine; Animals; Avoidance Learning; Brain; Caffeine; Central Nervous System Stimulants; Dopamine; Haloperidol; Male; Memory; Rats; Rats, Inbred Strains; Strychnine | 1984 |
Blockade by haloperidol of the increase in tryptophan hydroxylase activity induced by incubation of slices of brain stem with dibutyryl cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain Stem; Bucladesine; Caffeine; Calcium; Haloperidol; Male; Rats; Theophylline; Tryptophan Hydroxylase | 1982 |
Caffeine potentiation of apomorphine discrimination.
Topics: Animals; Apomorphine; Caffeine; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Prejudice; Rats | 1980 |
The locus coeruleus: actions of psychoactive drugs.
Topics: Action Potentials; Animals; Atropine; Caffeine; Chlorpromazine; Desipramine; Haloperidol; Locus Coeruleus; Male; Neurons; Nicotine; Norepinephrine; Physostigmine; Psychotropic Drugs; Rats; Scopolamine | 1983 |
Ethanol intake increases during continuous administration of amphetamine and nicotine, but not several other drugs.
Topics: Alcohol Drinking; Amphetamine; Animals; Caffeine; Drinking Behavior; Drug Implants; Female; Haloperidol; Lysergic Acid Diethylamide; Mescaline; Nicotine; Phencyclidine; Rats; Secobarbital | 1983 |
Self-injurious behavior produced in rats by daily caffeine and continuous amphetamine.
Topics: Amphetamine; Animals; Behavior, Animal; Caffeine; Drug Administration Schedule; Drug Implants; Haloperidol; Humans; Male; Motor Activity; Rats; Self Mutilation | 1982 |
Sleep spindles: pharmacological effects in humans.
Topics: Atropine; Azepines; Caffeine; Cerebral Cortex; Computers; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials; Flurazepam; Haloperidol; Humans; N-Methylscopolamine; Phenobarbital; Scopolamine; Scopolamine Derivatives; Sleep Stages; Thalidomide; Tryptophan | 1982 |
Up-regulation of neurotensin mRNA in the rat striatum after acute methamphetamine treatment.
Topics: Animals; Autoradiography; Caffeine; Corpus Striatum; Gene Expression Regulation; Haloperidol; Male; Methamphetamine; Neurotensin; Olfactory Bulb; Oligonucleotide Probes; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Substance P; Sulfur Radioisotopes; Time Factors | 1994 |
The effects of the atypical antipsychotics clozapine, remoxipride and risperidone on the contractile characteristics of rat skeletal muscle in vitro.
Topics: Animals; Antipsychotic Agents; Caffeine; Clozapine; Dantrolene; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Halothane; In Vitro Techniques; Muscle Contraction; Muscle Relaxants, Central; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Trifluoperazine | 1997 |
Dopaminergic agonists administered into the nucleus accumbens: effects on extracellular glutamate and on locomotor activity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Benzazepines; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Dopamine Antagonists; Glutamic Acid; Haloperidol; Male; Motor Activity; Nucleus Accumbens; Quinpirole; Rats; Rats, Sprague-Dawley; Salicylamides | 1998 |
Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat.
Topics: Animals; Caffeine; Genes, fos; Haloperidol; In Situ Hybridization; Neostriatum; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger | 1998 |
An improved low-permeability in vitro-model of the blood-brain barrier: transport studies on retinoids, sucrose, haloperidol, caffeine and mannitol.
Topics: Animals; Blood-Brain Barrier; Caffeine; Cells, Cultured; Colchicine; Culture Media, Serum-Free; Endothelium, Vascular; Haloperidol; Mannitol; Retinoids; Sucrose; Swine | 1999 |
Molecular and behavioral effects mediated by Gs-coupled adenosine A2a, but not serotonin 5-Ht4 or 5-Ht6 receptors following antipsychotic administration.
Topics: Adenosine; Animals; Antipsychotic Agents; Behavior, Animal; Caffeine; Catalepsy; Clozapine; Corpus Striatum; Cyclic AMP; Dopamine D2 Receptor Antagonists; Gene Expression Regulation; Genes, fos; GTP-Binding Protein alpha Subunits, Gs; Haloperidol; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D2; Receptors, Purinergic P1; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Second Messenger Systems; Serotonin; Serotonin Antagonists; Theophylline | 1999 |
The role of the D(2) dopamine receptor (D(2)R) in A(2A) adenosine receptor (A(2A)R)-mediated behavioral and cellular responses as revealed by A(2A) and D(2) receptor knockout mice.
Topics: Adenosine; Amphetamines; Animals; Caffeine; Catalepsy; Corpus Striatum; Dopamine Antagonists; Enkephalins; Gene Expression; Haloperidol; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic P1; RNA, Messenger | 2001 |
An animal model of nicotinic-acid-induced vasodilation: effect of haloperidol, caffeine and nicotine upon nicotinic acid response.
Topics: Animals; Antipsychotic Agents; Brain; Caffeine; Cerebrovascular Circulation; Disease Models, Animal; Haloperidol; Male; Niacin; Nicotine; Rats; Rats, Sprague-Dawley; Schizophrenia; Vasodilation | 2001 |
Caffeine and muscarinic antagonists act in synergy to inhibit haloperidol-induced catalepsy.
Topics: Animals; Caffeine; Catalepsy; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Muscarinic Antagonists; Rats; Rats, Wistar | 2003 |
Adenosine A2A receptors and depression.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Depression; Disease Models, Animal; Dopamine Antagonists; Drug Interactions; Haloperidol; Mice; Mice, Knockout; Motor Activity; Neurotransmitter Agents; Parkinsonian Disorders; Purines; Pyrimidines; Receptor, Adenosine A2A; Triazines; Triazoles | 2003 |
Involvement of adenosinergic receptor system in an animal model of tardive dyskinesia and associated behavioural, biochemical and neurochemical changes.
Topics: Adenosine; Akathisia, Drug-Induced; Animals; Antioxidants; Behavior, Animal; Brain; Caffeine; Catalase; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Haloperidol; Lipid Peroxidation; Male; Mastication; Maze Learning; Motor Activity; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Purinergic P1; Stereotyped Behavior; Superoxide Dismutase; Vasodilator Agents | 2006 |
Effects of N-n-butyl haloperidol iodide on L-type calcium channels and intracellular free calcium in rat ventricular myocytes.
Topics: Animals; Caffeine; Calcium; Calcium Channels, L-Type; Cells, Cultured; Central Nervous System Stimulants; Haloperidol; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Vasodilation | 2007 |
The effects of adenosine A2A receptor antagonists on haloperidol-induced movement disorders in primates.
Topics: Adenosine A2 Receptor Antagonists; Animals; Antipsychotic Agents; Caffeine; Catalepsy; Cebus; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Globus Pallidus; Haloperidol; Neurologic Examination; Purines; Pyrimidines; Receptor, Adenosine A2A; Saimiri; Triazoles; Xanthines | 2008 |
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Caffeine; Central Nervous System Stimulants; Chromosomes, Artificial, Bacterial; Clozapine; Cocaine; Corpus Striatum; Dopamine and cAMP-Regulated Phosphoprotein 32; Globus Pallidus; Haloperidol; Mice; Mice, Transgenic; Neurons; Organ Culture Techniques; Phosphorylation; Substantia Nigra | 2008 |
Antagonism of haloperidol-induced swim impairment in L-dopa and caffeine treated mice: a pre-clinical model to study Parkinson's disease.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Caffeine; Catalepsy; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Glutathione; Haloperidol; Levodopa; Male; Mice; Motor Activity; Parkinsonian Disorders; Posture; Superoxide Dismutase; Swimming | 2009 |
Caffeine withdrawal retains anticataleptic activity but Withania somnifera withdrawal potentiates haloperidol-induced catalepsy in mice.
Topics: Analysis of Variance; Animals; Caffeine; Catalepsy; Haloperidol; Mice; Nervous System; Plant Extracts; Withania | 2009 |
Differential actions of adenosine A1 and A2A antagonists on the effort-related effects of dopamine D2 antagonism.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Behavior, Animal; Caffeine; Central Nervous System Agents; Choice Behavior; Conditioning, Operant; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Feeding Behavior; Haloperidol; Male; Motivation; Purines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Xanthines | 2009 |
Adenosine antagonists reverse the cataleptic effects of haloperidol: implications for the treatment of Parkinson's disease.
Topics: Animals; Caffeine; Catalepsy; Dose-Response Relationship, Drug; Haloperidol; Male; Parkinson Disease; Purinergic P1 Receptor Antagonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Triazoles | 2009 |
Targeting pain-depressed behaviors in preclinical assays of pain and analgesia: drug effects on acetic acid-depressed locomotor activity in ICR mice.
Topics: Acetic Acid; Analgesia; Analgesics; Animals; Behavior, Animal; Benzene Derivatives; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Haloperidol; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Pain; Pain Measurement | 2009 |
Long-lasting resistance to haloperidol-induced catalepsy in male rats chronically treated with caffeine.
Topics: Animals; Caffeine; Catalepsy; Central Nervous System Stimulants; Disease Susceptibility; Dopamine D2 Receptor Antagonists; Haloperidol; Male; Neuroprotective Agents; Rats; Rats, Wistar; Time Factors | 2009 |
The stimulatory effects of caffeine with oseltamivir (Tamiflu) on light-dark behavior and open-field behavior in mice.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Antiviral Agents; Caffeine; Darkness; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Exploratory Behavior; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Haloperidol; Male; Mice; Motor Activity; Neurotransmitter Agents; Oseltamivir; Pyrimidines; Random Allocation; Triazoles; Xanthines | 2010 |
Psychosis following excessive ingestion of energy drinks in a patient with schizophrenia.
Topics: Adult; Affect; Antipsychotic Agents; Arousal; Beverages; Caffeine; Central Nervous System Stimulants; Disease Progression; Dose-Response Relationship, Drug; Haloperidol; Humans; Injections, Intramuscular; Male; Psychoses, Substance-Induced; Schizophrenia, Paranoid | 2010 |
Ecstacy-induced delayed rhabdomyolysis and neuroleptic malignant syndrome in a patient with a novel variant in the ryanodine receptor type 1 gene.
Topics: Anesthetics, Inhalation; Antipsychotic Agents; Body Temperature; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Creatine Kinase; Dantrolene; Disseminated Intravascular Coagulation; Female; Genetic Variation; Hallucinogens; Haloperidol; Halothane; Humans; Multiple Organ Failure; N-Methyl-3,4-methylenedioxyamphetamine; Neuroleptic Malignant Syndrome; Recurrence; Rhabdomyolysis; Ryanodine Receptor Calcium Release Channel; Spectrum Analysis; Young Adult | 2012 |
Caffeine has greater potency and efficacy than theophylline to reverse the motor impairment caused by chronic but not acute interruption of striatal dopaminergic transmission in rats.
Topics: Animals; Caffeine; Catalepsy; Corpus Striatum; Dopaminergic Neurons; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Skills; Oxidopamine; Parkinsonian Disorders; Rats; Theophylline | 2013 |
Tea component, epigallocatechin gallate, potentiates anticataleptic and locomotor-sensitizing effects of caffeine in mice.
Topics: Animals; Antipsychotic Agents; Caffeine; Catalepsy; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Lipid Peroxidation; Male; Mice; Motor Activity; Parkinsonian Disorders; Tea | 2015 |
Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducin.
Topics: Animals; Caffeine; Cytoskeletal Proteins; Dendritic Spines; Dopamine and cAMP-Regulated Phosphoprotein 32; Female; Haloperidol; Male; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Nucleus Accumbens; Phosphorylation; Psychotropic Drugs; Quinpirole | 2016 |
Sedative effect of Clozapine is a function of 5-HT
Topics: Animals; Antipsychotic Agents; Caffeine; Central Nervous System Stimulants; Clozapine; Dose-Response Relationship, Drug; Environment; Exploratory Behavior; Genotype; Haloperidol; Inhibition, Psychological; Mice; Mice, Knockout; Receptor, Serotonin, 5-HT2A; Risperidone; Serotonin Antagonists | 2017 |
Nicotine and caffeine modulate haloperidol-induced changes in postsynaptic density transcripts expression: Translational insights in psychosis therapy and treatment resistance.
Topics: Animals; Brain; Caffeine; Central Nervous System Agents; Cytoskeletal Proteins; Drug Interactions; Drug Resistance; Gene Expression; Haloperidol; Homer Scaffolding Proteins; Male; Motor Activity; Nerve Tissue Proteins; Nicotine; Post-Synaptic Density; Psychotic Disorders; Random Allocation; Rats, Sprague-Dawley; RNA, Messenger; Schizophrenia | 2018 |
Interplay between adenosine receptor antagonist and cyclooxygenase inhibitor in haloperidol-induced extrapyramidal effects in mice.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Caffeine; Catalepsy; Cyclooxygenase Inhibitors; Haloperidol; Male; Mice; Motor Activity; Naproxen; Purinergic P1 Receptor Antagonists; Treatment Outcome | 2018 |