caffeine and furosemide

caffeine has been researched along with furosemide in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19909 (15.52)18.7374
1990's2 (3.45)18.2507
2000's19 (32.76)29.6817
2010's23 (39.66)24.3611
2020's5 (8.62)2.80

Authors

AuthorsStudies
Ishii, A; Karasawa, A; Kawakita, T; Kubo, K; Mizumoto, H; Nonaka, H; Shimada, J; Suzuki, F1
Ishii, A; Karasawa, A; Kubo, K; Mizumoto, H; Nonaka, H; Ohno, T; Shimada, J; Suzuki, F1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Jolivette, LJ; Ward, KW1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Botta, M; Dreassi, E; Falchi, F; Maga, G; Santucci, A; Schenone, S; Zizzari, AT1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Conradi, R; Lee, PH; Shanmugasundaram, V1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Akamatsu, M1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Alexander, MJ1
Biaggioni, I; Branch, RA; Jackson, EK; Paul, S; Robertson, D1
Benham, CD; Bolton, TB; Byrne, NG; Large, WA1
Appell, LH; Blythe, LL; Craig, AM; Slizeski, ML1
Cabrini, GP; Giovanelli, M; Infuso, L; Nicola, GC1
Ferguson, DR1
Dibbern, HW1
Connett, RJ; Gilda, EN; Hays, ET1
Ashley, CC; Lea, TJ1
Glavaski, A; Jeftinija, K; Jeftinija, S; Jeremic, A; Stevanovic, J1
Lawrence, JR; Neu, TR; Swerhone, GD; Wassenaar, LI1
Bouchard, F; Gosselin, P; Lemieux, M; Mateescu, MA; Paquin, J1
Chalasani, N; Hall, SD; Jones, DR; Mattar, S; Tandra, S; Vuppalanchi, R1
Alashi, Y; Biliaminu, SA; Owoyele, BV; Oyewole, AL1
Fukami, T; Furuishi, T; Kitagawa, S; Nagase, H; Sakane, T; Teraoka, R; Tode, C; Ueda, H; Yutani, R1
Barco, S; Bruschettini, M; Cangemi, G; Ley, D; Romantsik, O; Tripodi, G1
Correia, AT; Guimarães, LL; Roveri, V; Toma, W1
Giner, B; Lafuente, C; Lomba, L; Polo, A; Werner, Á1
Allison, DB; Baker, BA; Coffey, CS; Steiner, D1
Crowley, DC; Evans, M; Guthrie, N; Langston, J; Sulley, AM1

Reviews

2 review(s) available for caffeine and furosemide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022

Trials

3 trial(s) available for caffeine and furosemide

ArticleYear
Pharmacokinetic and pharmacodynamic alterations in the Roux-en-Y gastric bypass recipients.
    Annals of surgery, 2013, Volume: 258, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Biotransformation; Caffeine; Case-Control Studies; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Dextromethorphan; Diuretics; Excitatory Amino Acid Antagonists; Female; Furosemide; GABA Modulators; Gastric Bypass; Humans; Hypoglycemic Agents; Male; Midazolam; Middle Aged; Omeprazole; Pharmacokinetics; Tandem Mass Spectrometry; Tolbutamide; Young Adult

2013
A randomized double-blind placebo-controlled clinical trial of a product containing ephedrine, caffeine, and other ingredients from herbal sources for treatment of overweight and obesity in the absence of lifestyle treatment.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2004, Volume: 28, Issue:11

    Topics: Adult; Anti-Obesity Agents; Benzyl Alcohols; Body Mass Index; Caffeine; Cola; Double-Blind Method; Drug Combinations; Ephedra sinica; Ephedrine; Female; Glucosides; Humans; Logistic Models; Male; Middle Aged; Obesity; Phytotherapy; Plants, Medicinal; Salix; Statistics, Nonparametric; Time Factors; Weight Loss

2004
Pain Bloc-R Alleviates Unresolved, Non-Pathological Aches and Discomfort in Healthy Adults-A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
    Nutrients, 2020, Jun-19, Volume: 12, Issue:6

    Topics: Acetylcarnitine; Adult; Angelica; Berberine Alkaloids; Caffeine; Chronic Pain; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glutamates; Humans; Hydrochloric Acid; Male; Middle Aged; Pain Management; Plant Bark; Plant Extracts; Plant Roots; Salix; Sex Factors; Thiamine; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin D; Vitamins; Young Adult

2020

Other Studies

53 other study(ies) available for caffeine and furosemide

ArticleYear
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure.
    Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16

    Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines

1992
8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Animals; Diuretics; Indicators and Reagents; Kidney; Kidney Function Tests; Kinetics; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Purinergic; Structure-Activity Relationship; Xanthines

1991
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:9

    Topics: Humans; Lipids; Membranes, Artificial; Permeability; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrazoles; Pyrimidines

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Treatment of acute alcoholism.
    JACEP, 1976, Volume: 5, Issue:8

    Topics: Alcoholic Intoxication; Caffeine; Furosemide; Humans; Intubation, Gastrointestinal

1976
Caffeine potentiates the renin response to furosemide in rats. Evidence for a regulatory role of endogenous adenosine.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:1

    Topics: Adenosine; Animals; Caffeine; Drug Synergism; Furosemide; Kidney; Male; Rats; Rats, Inbred Strains; Renin; Xanthines

1989
Action of externally applied adenosine triphosphate on single smooth muscle cells dispersed from rabbit ear artery.
    The Journal of physiology, 1987, Volume: 387

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Caffeine; Chlorides; Egtazic Acid; Female; Furosemide; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Potassium; Rabbits; Sodium

1987
Evaluation of the potential for interference by dimethyl sulfoxide (DMSO) in drug detection in racing animals.
    Journal of veterinary pharmacology and therapeutics, 1987, Volume: 10, Issue:4

    Topics: Acepromazine; Animals; Apomorphine; Caffeine; Chromatography, Thin Layer; Clonixin; Cocaine; Dimethyl Sulfoxide; Drug Interactions; Female; Furosemide; Horses; Lidocaine; Pharmaceutical Preparations; Phenylbutazone

1987
[Changes in cerebrospinal fluid pressure in closed cranial injuries as related to drug therapy].
    Minerva neurochirurgica, 1967, Volume: 11, Issue:3

    Topics: Brain Edema; Brain Injuries; Caffeine; Contusions; Dexamethasone; Furosemide; Hematoma, Subdural; Intracranial Pressure; Phytotherapy; Plants, Medicinal

1967
Effects of frusemide on sodium and water transport by the isolated toad bladder.
    British journal of pharmacology and chemotherapy, 1966, Volume: 27, Issue:3

    Topics: Adenine Nucleotides; Animals; Anura; Arginine; Biological Transport, Active; Caffeine; Furosemide; Sodium; Urinary Bladder; Vasopressins

1966
[Experiments with an in vitro model for the determination of gastroenteric absorption quota].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:2

    Topics: Aminopyrine; Aspirin; Caffeine; Digestive System Physiological Phenomena; Furosemide; Intestinal Absorption; Lipids; Models, Biological; Phenacetin; Spectrophotometry; Tolbutamide

1966
Involvement of transport of H+ equivalents in activation-induced alkaline shift in frog muscle.
    The American journal of physiology, 1984, Volume: 247, Issue:5 Pt 1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acetazolamide; Acid-Base Equilibrium; Amiloride; Animals; Biological Transport, Active; Caffeine; Calcium; Furosemide; Hydrogen-Ion Concentration; Ion Channels; Muscle Contraction; Muscles; Potassium; Rana pipiens; Sodium; Time Factors

1984
Carbon dioxide or bicarbonate ions release Ca2+ from internal stores in crustacean myofibrillar bundles.
    The Journal of membrane biology, 1981, Volume: 61, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Aequorin; Animals; Bicarbonates; Brachyura; Caffeine; Calcium; Calcium-Transporting ATPases; Carbon Dioxide; Furosemide; Hydrogen-Ion Concentration; Magnesium; Muscles; Sarcoplasmic Reticulum; Thoracica

1981
ATP stimulates calcium-dependent glutamate release from cultured astrocytes.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: 4-Chloromercuribenzenesulfonate; Adenosine Triphosphate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Caffeine; Calcium Signaling; Calcium-Transporting ATPases; Cells, Cultured; Cerebral Cortex; Chelating Agents; Chloride Channels; Chromatography, High Pressure Liquid; Egtazic Acid; Enzyme Inhibitors; Estrenes; Furosemide; Glutamic Acid; Ion Transport; Nitrobenzoates; Phosphatidylinositol Diacylglycerol-Lyase; Pyrrolidinones; Rats; Ryanodine; Sodium; Thapsigargin; Type C Phospholipases

2001
Effects of selected pharmaceuticals on riverine biofilm communities.
    Canadian journal of microbiology, 2005, Volume: 51, Issue:8

    Topics: Bacteria; Biofilms; Bioreactors; Caffeine; Carbamazepine; Carbon Isotopes; Colony Count, Microbial; Drug Prescriptions; Ecosystem; Furosemide; Ibuprofen; In Situ Hybridization, Fluorescence; Microscopy, Confocal; Pharmaceutical Preparations; Rivers

2005
The NCI-N87 cell line as a gastric epithelial barrier model for drug permeability assay.
    Biochemical and biophysical research communications, 2011, Sep-02, Volume: 412, Issue:3

    Topics: Absorption; Cadherins; Caffeine; Cell Line; Drug Evaluation; Electric Impedance; Furosemide; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Membrane Proteins; Models, Biological; Pharmacokinetics; Phosphoproteins; Zonula Occludens-1 Protein

2011
Effect of taurine and caffeine on plasma c-reactive protein and calcium in Wistar rats.
    African journal of medicine and medical sciences, 2015, Volume: 44, Issue:3

    Topics: Animals; Biomarkers; C-Reactive Protein; Caffeine; Calcium; Calcium Channel Blockers; Central Nervous System Stimulants; Furosemide; Nifedipine; Rats, Wistar; Sodium Potassium Chloride Symporter Inhibitors; Taurine

2015
Improving the Solid-State Photostability of Furosemide by Its Cocrystal Formation.
    Chemical & pharmaceutical bulletin, 2019, Volume: 67, Issue:9

    Topics: Caffeine; Crystallization; Drug Stability; Furosemide; Light; Niacinamide; Spectrophotometry; Urea

2019
A LC-MS/MS method for the quantification of caffeine, betamethasone, clonidine and furosemide in cerebrospinal fluid of preterm infants.
    Journal of pharmaceutical and biomedical analysis, 2020, Feb-05, Volume: 179

    Topics: Betamethasone; Caffeine; Chromatography, Liquid; Clonidine; Female; Furosemide; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Male; Reproducibility of Results; Tandem Mass Spectrometry

2020
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:59

    Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical

2022
Deep eutectic solvents based on sugars for oral applications.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2023, Volume: 191

    Topics: Caffeine; Deep Eutectic Solvents; Furosemide; Solubility; Solvents; Sugars; Water; Xylitol

2023