caffeine and fluoxetine

caffeine has been researched along with fluoxetine in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.33)18.7374
1990's7 (16.28)18.2507
2000's9 (20.93)29.6817
2010's21 (48.84)24.3611
2020's5 (11.63)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Sen, S; Sinha, N1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gibaldi, M1
Burket, RC; Hodgin, JD1
Callaway, CW; Geyer, MA; Rempel, NL1
Brøsen, K; Gram, LF; Jeppesen, U; Loft, S; Poulsen, HE; Vistisen, K1
Borrell, L; Foreyt, JP; Haddock, CK; Poston, WS1
Aunis, D; Burgun, C; Humblot, N; Thiriet, N; Zwiller, J1
Kaneko, S; Kawata, Y; Kondo, T; Mizuno, K; Murakami, T; Okada, M; Wada, K1
Esser, MJ; Reid, AR; Sawynok, J1
Liang, JH; Liu, RK; Sun, HL; Wang, XH; Ye, XF; Zheng, JW1
Caboche, J; Girault, JA; Hervé, D; Pagès, C; Valjent, E1
Hong, Z; Kelly, RF; Lang, IM; Murar, J; Nelson, DP; Rezaie-Majd, S; Varghese, A; Weir, EK1
Alici, T; Aygoren, MO; Kayir, H; Saglam, E; Uzbay, IT1
André, C; Blaise, C; Gagné, F; Salazar, M1
Amri, H; Bartels, BK; Beeson, E; Bergner, CL; Cachat, JM; Canavello, PR; Egan, RJ; Elegante, MF; Elkhayat, SI; Glasgow, E; Hart, PC; Kalueff, AV; Mohnot, S; Tien, AK; Tien, DH; Zukowska, Z1
Colwill, RM; Creton, R; Pelkowski, SD; Richendrfer, H1
Amaral, VC; Campos, KF; Miguel, TT; Nunes-de-Souza, RL; Rico, JL1
Bohner, LO; Costa, AP; De Lima, TC; Lino-de-Oliveira, C; Santos, EC; Silva, CF; Vieira, C1
Baca, S; Martinez Gomez, DA; Walsh, EJ1
Carrilho, MC; Francisco, RP; Krebs, VL; Lopes, LM; Lopes, MA; Zugaib, M1
Aickareth, G; Bajaj, R; Durgam, A; Jamal, F; Mathews, M1
Doboszewska, U; Dudka, J; Herbet, M; Kanadys, A; Korga, A; Ostrowska, M; Poleszak, E; Serefko, A; Świąder, K; Szopa, A; Terlecka, J; Wlaź, A; Wlaź, P; Wośko, S; Wróbel, A; Wyska, E1
Afsa, S; Hamden, K; Lara Martin, PA; Mansour, HB1
Akerman, J; González Cautela, BV; Pfaus, JG; Quintana, GR1
Brandão, CJ; de Souza, RC; Dos Santos, TL; Godoy, AA; Kummrow, F; Pinto, E1
Baldinelli, A; Battistoni, G; Ciavattini, A; Delli Carpini, G; Di Giuseppe, J; Giannella, L; Montironi, R; Pozzi, M1
Ghasemi, JB; Hosseini, E; Shekarchi, M1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN1

Reviews

4 review(s) available for caffeine and fluoxetine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug interactions: Part I.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5

    Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine

1992
Challenges in obesity management.
    Southern medical journal, 1998, Volume: 91, Issue:8

    Topics: 1-Naphthylamine; Adrenergic beta-Agonists; Appetite Depressants; Behavior Therapy; Caffeine; Cyclobutanes; Diethylpropion; Ephedrine; Fenfluramine; Fluoxetine; Humans; Lactones; Leptin; Lipase; Obesity; Orlistat; Phentermine; Proteins; Sertraline

1998
Foetal ductus arteriosus constriction unrelated to non-steroidal anti-Inflammatory drugs: a case report and literature review.
    Annals of medicine, 2021, Volume: 53, Issue:1

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Cesarean Section; Constriction; Constriction, Pathologic; Ductus Arteriosus; Female; Fluoxetine; Humans; Naphazoline; Pesticides; Pharmaceutical Preparations; Polyphenols; Pregnancy; Solvents; Ultrasonography, Prenatal

2021

Trials

1 trial(s) available for caffeine and fluoxetine

ArticleYear
Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine.
    European journal of clinical pharmacology, 1996, Volume: 51, Issue:1

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Chromatography, High Pressure Liquid; Citalopram; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Humans; Male; Mephenytoin; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sparteine

1996

Other Studies

38 other study(ies) available for caffeine and fluoxetine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Fluoxetine treatment of a depressed patient susceptible to malignant hyperthermia.
    The American journal of psychiatry, 1989, Volume: 146, Issue:5

    Topics: Adolescent; Caffeine; Depressive Disorder; Disease Susceptibility; Female; Fluoxetine; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction

1989
Serotonin1B receptor activation mimics behavioral effects of presynaptic serotonin release.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Caffeine; Designer Drugs; Dopamine Agents; Dose-Response Relationship, Drug; Fluoxetine; Indoles; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Scopolamine; Serotonin; Serotonin Receptor Agonists; Synapses

1993
Cocaine and fluoxetine induce the expression of the hVH-5 gene encoding a MAP kinase phosphatase.
    Brain research. Molecular brain research, 1998, Nov-20, Volume: 62, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Amphetamine; Animals; Caffeine; Central Nervous System Stimulants; Cocaine; Drug Interactions; Dual-Specificity Phosphatases; Enzyme Induction; Fluoxetine; Genes, Immediate-Early; Immediate-Early Proteins; Male; Nerve Tissue Proteins; Protein Tyrosine Phosphatases; Rats; Rats, Wistar

1998
Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin.
    The European journal of neuroscience, 1999, Volume: 11, Issue:1

    Topics: Adenosine; Animals; Antihypertensive Agents; Biological Transport; Caffeine; Central Nervous System Stimulants; Fluoxetine; Hippocampus; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quipazine; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Theobromine; Theophylline; Vasodilator Agents

1999
Peripheral antinociceptive actions of desipramine and fluoxetine in an inflammatory and neuropathic pain test in the rat.
    Pain, 1999, Volume: 82, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Caffeine; Desipramine; Drug Evaluation, Preclinical; Fluoxetine; Male; Neuralgia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Spinal Nerves

1999
Buspirone-induced antinociception is mediated by L-type calcium channels and calcium/caffeine-sensitive pools in mice.
    Psychopharmacology, 2003, Volume: 166, Issue:3

    Topics: 5-Hydroxytryptophan; Analgesics; Animals; Buspirone; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Central Nervous System Stimulants; Chelating Agents; Egtazic Acid; Female; Fluoxetine; Injections, Intraventricular; Mice; Nifedipine; Pain Measurement; Reaction Time; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ryanodine; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

2003
Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain.
    The European journal of neuroscience, 2004, Volume: 19, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzazepines; Brain; Caffeine; Central Nervous System Stimulants; Cocaine; Desipramine; Dopamine Antagonists; Dronabinol; Enzyme Activation; Fluoxetine; Immunohistochemistry; Male; Mice; Mitogen-Activated Protein Kinases; Morphine; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Scopolamine; Selective Serotonin Reuptake Inhibitors

2004
Increased release of serotonin from rat ileum due to dexfenfluramine.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 287, Issue:5

    Topics: 4-Aminopyridine; Animals; Caffeine; Calcium; Chromatography, High Pressure Liquid; Cytosol; Dexfenfluramine; Fluoxetine; Hypertension, Pulmonary; Ileum; Male; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists

2004
Discriminative stimulus properties of tianeptine.
    Psychopharmacology, 2006, Volume: 183, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Cyclohexanols; Discrimination Learning; Discrimination, Psychological; Fluoxetine; Male; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Thiazepines; Venlafaxine Hydrochloride

2006
Effects of pharmaceutical products and municipal wastewaters on temperature-dependent mitochondrial electron transport activity in Elliptio complanata mussels.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2006, Volume: 143, Issue:4

    Topics: Bivalvia; Caffeine; Carbamazepine; Cholestanol; Cotinine; Electron Transport; Fluoxetine; Ibuprofen; Lipid Peroxidation; Mitochondria; Novobiocin; Pharmaceutical Preparations; Sewage; Temperature; Trimethoprim; Xenobiotics

2006
Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish.
    Behavioural brain research, 2009, Dec-14, Volume: 205, Issue:1

    Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Disease Models, Animal; Ethanol; Female; Fluoxetine; Hydrocortisone; Male; Motor Activity; Phenotype; Pheromones; Species Specificity; Stress, Psychological; Zebrafish

2009
On the edge: pharmacological evidence for anxiety-related behavior in zebrafish larvae.
    Behavioural brain research, 2012, Mar-01, Volume: 228, Issue:1

    Topics: Animals; Anxiety; Caffeine; Cues; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Spatial Behavior; Swimming; Zebrafish

2012
Ethopharmacological evaluation of the rat exposure test: a prey-predator interaction test.
    Behavioural brain research, 2013, Mar-01, Volume: 240

    Topics: Adrenergic alpha-2 Receptor Antagonists; Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Diazepam; Escape Reaction; Factor Analysis, Statistical; Fluoxetine; Food Chain; Imipramine; Male; Mice; Motor Activity; Posture; Predatory Behavior; Rats; Rats, Long-Evans; Time Factors; Yohimbine

2013
A proposal for refining the forced swim test in Swiss mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Aug-01, Volume: 45

    Topics: Animals; Antidepressive Agents; Apomorphine; Caffeine; Central Nervous System Stimulants; Desipramine; Disease Models, Animal; Fluoxetine; Imipramine; Immobility Response, Tonic; Male; Mice; Principal Component Analysis; Swimming; Time Factors

2013
Lethal and sublethal effects of selected PPCPs on the freshwater rotifer, Plationus patulus.
    Environmental toxicology and chemistry, 2015, Volume: 34, Issue:4

    Topics: Acetaminophen; Animals; Caffeine; Cosmetics; Fluoxetine; Food Chain; Fresh Water; Lethal Dose 50; Mexico; Pharmaceutical Preparations; Rotifera; Triclosan; Water Pollutants, Chemical; Water Pollution, Chemical

2015
Fetal ductus arteriosus constriction and closure: analysis of the causes and perinatal outcome related to 45 consecutive cases.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2016, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Caffeine; Central Nervous System Stimulants; Constriction, Pathologic; Ductus Arteriosus; Echocardiography, Doppler, Color; Echocardiography, Doppler, Pulsed; Female; Fluoxetine; Heart Failure; Humans; Hypertension, Pulmonary; Isoxsuprine; Maternal Exposure; Maternal-Fetal Exchange; Naphazoline; Nasal Decongestants; Pesticides; Pregnancy; Remission, Spontaneous; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Tricuspid Valve Insufficiency; Ultrasonography, Prenatal; Vasodilator Agents; Ventricular Dysfunction, Right; Young Adult

2016
A Case of Caffeine Intolerance With Long-Term Use of Fluoxetine.
    The primary care companion for CNS disorders, 2017, Jun-01, Volume: 19, Issue:3

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Caffeine; Central Nervous System Stimulants; Coffee; Depressive Disorder; Drug Interactions; Female; Fluoxetine; Humans

2017
Chronic treatment with caffeine and its withdrawal modify the antidepressant-like activity of selective serotonin reuptake inhibitors in the forced swim and tail suspension tests in mice. Effects on Comt, Slc6a15 and Adora1 gene expression.
    Toxicology and applied pharmacology, 2017, 12-15, Volume: 337

    Topics: Amino Acid Transport Systems, Neutral; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Cerebral Cortex; Citalopram; Depression; Disease Models, Animal; Drug Administration Schedule; Fluoxetine; Hindlimb Suspension; Male; Mice; Motor Activity; Receptor, Adenosine A1; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Swimming; Time Factors

2017
Occurrence of 40 pharmaceutically active compounds in hospital and urban wastewaters and their contribution to Mahdia coastal seawater contamination.
    Environmental science and pollution research international, 2020, Volume: 27, Issue:2

    Topics: Caffeine; Environmental Monitoring; Fluoxetine; Hospitals; Pharmaceutical Preparations; Salicylic Acid; Seawater; Sulfadiazine; Sulfamethizole; Tunisia; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical

2020
Acute caffeine reverses the disruptive effects of chronic fluoxetine on the sexual behavior of female and male rats.
    Psychopharmacology, 2021, Volume: 238, Issue:3

    Topics: Animals; Caffeine; Copulation; Ejaculation; Estradiol; Female; Fluoxetine; Libido; Male; Progesterone; Rats; Rats, Long-Evans; Selective Serotonin Reuptake Inhibitors; Sexual Behavior, Animal

2021
Occurrence of caffeine, fluoxetine, bezafibrate and levothyroxine in surface freshwater of São Paulo State (Brazil) and risk assessment for aquatic life protection.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:16

    Topics: Bezafibrate; Brazil; Caffeine; Environmental Monitoring; Fluoxetine; Fresh Water; Risk Assessment; Thyroxine; Water Pollutants, Chemical

2021
Simultaneous Determination of Adulterants in Dietary Food Supplements Using Multivariate Data Analysis after Preconcentration with Novel Nanosorbents and Chromatographic Measurement.
    Journal of AOAC International, 2022, Sep-06, Volume: 105, Issue:5

    Topics: Caffeine; Chromatography, High Pressure Liquid; Data Analysis; Dietary Supplements; Ephedrine; Fluoxetine

2022
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
    Chemical biology & drug design, 2016, Volume: 88, Issue:6

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain

2016