caffeine and erythromycin

caffeine has been researched along with erythromycin in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.56)18.7374
1990's5 (12.82)18.2507
2000's12 (30.77)29.6817
2010's18 (46.15)24.3611
2020's3 (7.69)2.80

Authors

AuthorsStudies
Belas, F; Chaudhary, AK; Cvetkovic, M; Dempsey, PJ; Fromm, MF; Kim, RB; Leake, B; Roden, DM; Roden, MM; Wandel, C; Wilkinson, GR; Wood, AJ1
Jolivette, LJ; Ward, KW1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abdel-Raziq, MS; Gabr, MT1
Berchou, RC; Kareti, D; LeWitt, PA; Nelson, MV1
Bukowskyj, M; Munt, PW; Nakatsu, K1
Taylor, D1
Breimer, DD; Tanaka, E1
Bastien, MC; Demers, C; Gascon-Barré, M; Provencher, SJ; Villeneuve, JP1
Ashoush, R; Farah, E; Ghayad, E; Jebara, V; Karam, B1
Grand, F; Guitton, J; Kilinc, I; Sarkis, A1
Fuhr, U; Kober, S; Mutschler, E; Spahn-Langguth, H; Zaigler, M1
Speer, CP; Thomas, W1
Boleda, MA; Galceran, MA; Ventura, F1
Dupuis, R; Everhart, JE; Everson, GT; Gillespie, BW; Goodrich, NP; Herman, A; Hoefs, JC; Lauriski, S; Milne, N; Niemann, CU; Olthoff, KM1
Chen, F; Chen, H; Fu, W; Luo, W; Meng, F; Xie, Y; Yang, X; Ye, T; Young, K1
Almeida, CM; Benoliel, MJ; Cardoso, VV; de Jesus Gaffney, V; Loureiro, M; Mota-Filipe, H; Pinto, RA; Thiemermann, C1
Behrens, M; Cheled-Shoval, S; Di Pizio, A; Korb, A; Meyerhof, W; Niv, MY; Uni, Z1
Adedayo, O; Adeoye-Isijola, MO; Coopoosamy, RM; Okon, V; Olajuyigbe, OO1
Cao, X; Lu, Y; Song, S; Wang, C; Xiu, C; Zhang, M1
Cao, Z; Li, X; Lu, Y; Mao, R; Song, S; Sun, B; Wang, C; Wang, R; Zhang, M1
Chen, F; Cheng, R; Dai, HR; Ding, XS; Guo, HL; He, X; Hu, YH; Jiao, Z; Liu, Y; Lu, KY; Xu, J1

Reviews

5 review(s) available for caffeine and erythromycin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Theophylline reassessed.
    Annals of internal medicine, 1984, Volume: 101, Issue:1

    Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; Caffeine; Contraceptives, Oral; Cooking; Cystic Fibrosis; Drug Interactions; Erythromycin; Female; Heart Diseases; Histamine H2 Antagonists; Humans; Hypoxia; Infections; Kinetics; Liver Diseases; Lung Diseases, Obstructive; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Respiration Disorders; Sleep; Smoking; Theophylline

1984
Pharmacokinetic interactions involving clozapine.
    The British journal of psychiatry : the journal of mental science, 1997, Volume: 171

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antipsychotic Agents; Caffeine; Cimetidine; Clozapine; Drug Interactions; Erythromycin; Fluvoxamine; Humans; Risperidone; Selective Serotonin Reuptake Inhibitors

1997
In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease.
    Journal of clinical pharmacy and therapeutics, 1997, Volume: 22, Issue:4

    Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Erythromycin; Humans; Liver Diseases; Liver Function Tests; Trimethadione

1997
Prevention and therapy of bronchopulmonary dysplasia - evidence and clinical practice.
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2007, Volume: 9, Issue:3

    Topics: Antioxidants; Bronchopulmonary Dysplasia; Caffeine; Diuretics; Erythromycin; Humans; Incidence; Infant, Newborn; Nitric Oxide; Oxygen; Ureaplasma urealyticum

2007

Other Studies

34 other study(ies) available for caffeine and erythromycin

ArticleYear
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
    Pharmaceutical research, 1999, Volume: 16, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Male; Mice; Oxidoreductases, N-Demethylating; Pharmacokinetics; Substrate Specificity

1999
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Structure-based design, synthesis, and evaluation of structurally rigid donepezil analogues as dual AChE and BACE-1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2018, 09-15, Volume: 28, Issue:17

    Topics: Acetylcholinesterase; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Blood-Brain Barrier; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Crystallography, X-Ray; Donepezil; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2018
Pharmacokinetic evaluation of erythromycin and caffeine administered with bromocriptine.
    Clinical pharmacology and therapeutics, 1990, Volume: 47, Issue:6

    Topics: Adult; Bromocriptine; Caffeine; Drug Interactions; Erythromycin; Humans; Male; Middle Aged

1990
Effect of cyclosporine A on cytochrome P-450-mediated drug metabolism in the partially hepatectomized rat.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:4

    Topics: Aminopyrine; Animals; Biotransformation; Blotting, Northern; Caffeine; Carbon Radioisotopes; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Activation; Erythromycin; Hepatectomy; Isoenzymes; Liver Regeneration; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity

1999
Ergotism precipitated by erythromycin: a rare case of vasospasm.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2000, Volume: 19, Issue:1

    Topics: Abscess; Adult; Anti-Bacterial Agents; Caffeine; Drug Combinations; Ergotamine; Ergotism; Erythromycin; Humans; Ischemia; Male; Migraine Disorders

2000
Application of isotopic ratio mass spectrometry for the in vitro determination of demethylation activity in human liver microsomes using N-methyl-13C-labeled substrates.
    Analytical biochemistry, 2002, Jul-15, Volume: 306, Issue:2

    Topics: Aminopyrine; Caffeine; Carbon Isotopes; Cytochrome P-450 Enzyme System; Erythromycin; Humans; In Vitro Techniques; Mass Spectrometry; Methylation; Microsomes, Liver; Oxidoreductases, N-Demethylating

2002
Rate-limiting biotransformation of triamterene is mediated by CYP1A2.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:7

    Topics: Caffeine; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythromycin; Humans; Hydroxylation; Ketoconazole; Kinetics; Microsomes, Liver; Omeprazole; Quinidine; Substrate Specificity; Sulfuric Acid Esters; Theophylline; Triamterene

2005
Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments.
    Environmental pollution (Barking, Essex : 1987), 2011, Volume: 159, Issue:6

    Topics: Acetaminophen; Caffeine; Cocaine; Cotinine; Environmental Monitoring; Erythromycin; Halogenation; Illicit Drugs; Iohexol; Kinetics; Nicotine; Osmosis; Ozone; Pharmaceutical Preparations; Ultrafiltration; Water Pollutants, Chemical; Water Pollution, Chemical; Water Purification; Water Supply

2011
Functional elements associated with hepatic regeneration in living donors after right hepatic lobectomy.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2013, Volume: 19, Issue:3

    Topics: Adult; Alanine Transaminase; Bilirubin; Breath Tests; Caffeine; Cholates; Colorado; Erythromycin; Female; Hepatectomy; Humans; International Normalized Ratio; Linear Models; Liver; Liver Circulation; Liver Regeneration; Liver Transplantation; Living Donors; Male; Middle Aged; Organ Size; Predictive Value of Tests; Prospective Studies; Recovery of Function; San Francisco; Serum Albumin; Serum Albumin, Human; Time Factors; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Treatment Outcome; Young Adult

2013
Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China.
    Environmental science and pollution research international, 2013, Volume: 20, Issue:8

    Topics: Acetaminophen; Caffeine; Carbamazepine; Carbon; China; Ciprofloxacin; DEET; Environmental Monitoring; Erythromycin; Nitrates; Nitrites; Nitrogen; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Rivers; Sulfamethoxazole; Trimethoprim; Water Pollutants, Chemical; Water Quality

2013
Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water.
    Environmental toxicology and chemistry, 2016, Volume: 35, Issue:11

    Topics: Animals; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Drinking Water; Environmental Exposure; Erythromycin; Kidney; Liver; Models, Theoretical; Pharmaceutical Preparations; Rats; Rats, Wistar; Tandem Mass Spectrometry; Water Purification

2016
From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds.
    Molecules (Basel, Switzerland), 2017, May-17, Volume: 22, Issue:5

    Topics: Animals; Avoidance Learning; Beak; Caffeine; Catechin; Chickens; Erythromycin; Gene Expression; HEK293 Cells; Humans; Ligands; Nicotine; Quinine; Receptors, G-Protein-Coupled; Taste Threshold; Transfection

2017
In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens.
    Acta biochimica Polonica, 2017, Volume: 64, Issue:2

    Topics: Anti-Bacterial Agents; Bacteria; Caffeine; Chloramphenicol; Drug Synergism; Erythromycin; Humans; Kanamycin; Metronidazole; Microbial Sensitivity Tests; Nalidixic Acid; Tetracycline

2017
Distribution and ecological risks of pharmaceuticals and personal care products with different anthropogenic stresses in a coastal watershed of China.
    Chemosphere, 2022, Volume: 303, Issue:Pt 2

    Topics: Caffeine; Carbamazepine; China; Cosmetics; Ecosystem; Environmental Monitoring; Erythromycin; Pharmaceutical Preparations; Risk Assessment; Rivers; Sulfamethoxazole; Water; Water Pollutants, Chemical

2022
Contamination, transport, and ecological risks of pharmaceuticals and personal care products in a large irrigation region.
    The Science of the total environment, 2022, Dec-10, Volume: 851, Issue:Pt 1

    Topics: Caffeine; China; Cosmetics; Ecosystem; Environmental Monitoring; Erythromycin; Humans; Norfloxacin; Ofloxacin; Pharmaceutical Preparations; Risk Assessment; Sulfamethoxazole; Water Pollutants, Chemical

2022
Population pharmacokinetic modeling of caffeine in preterm infants with apnea of prematurity: New findings from concomitant erythromycin and AHR genetic polymorphisms.
    Pharmacological research, 2022, Volume: 184

    Topics: Apnea; Caffeine; Erythromycin; Humans; Infant; Infant, Newborn; Infant, Premature; Polymorphism, Genetic; Receptors, Aryl Hydrocarbon

2022