caffeine has been researched along with enprofylline in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (25.00) | 18.7374 |
| 1990's | 8 (33.33) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Bridson, PK; Daly, JW; Hide, I | 1 |
| Daly, JW; Padgett, WL; Shamim, MT; Ukena, D | 1 |
| Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE | 1 |
| Daly, JW; Diekmann, M; Jacobson, KA; Müller, CE; Padgett, WL; Qurishi, R; Thorand, M | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Bertarelli, DC; Borrmann, T; Florin, NC; Hinz, S; Li, W; Müller, CE; Scheiff, AB | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Azuaje, J; Carbajales, C; Crespo, A; El Maatougui, A; Escalante, L; García-Mera, X; González-Gómez, M; Gutiérrez-de-Terán, H; Miguez, G; Sotelo, E | 1 |
| Gaba, S; Gupta, GD; Monga, V; Patel, R; Saini, A; Singh, G | 1 |
| Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S | 1 |
| Dulloo, AG; Girardier, L; Seydoux, J | 1 |
| Lenders, JW; Smits, P; Thien, T | 1 |
| Brackett, LE; Daly, JW; Shamim, MT | 1 |
| Schouten, J; Smits, P; Thien, T | 2 |
| Andersson, KE; Kjellin, G; Persson, CG | 1 |
| Grgurinovich, N | 1 |
| Edvinsson, L; Fletcher, R; Monti, M; Ranklev, E | 1 |
| Cortijo, J; Morcillo, EJ; Orón, JD; Perpiñá, M | 1 |
| De Sarro, A; De Sarro, G; Grasso, S; Nava, F; Zappala, M | 1 |
| Gean, PW; Lu, KT; Wu, SP | 1 |
2 review(s) available for caffeine and enprofylline
| Article | Year |
|---|---|
Adenosine receptor antagonists: Recent advances and therapeutic perspective.
Topics: Dose-Response Relationship, Drug; Humans; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Structure-Activity Relationship | 2022 |
Effects of enprofylline and theophylline may show the role of adenosine.
Topics: Adenosine; Animals; Asthma; Brain; Bronchodilator Agents; Caffeine; Diuresis; Fatty Acids, Nonesterified; Gastric Acid; Heart; Humans; Kidney; Kinetics; Lung; Natriuresis; Phosphodiesterase Inhibitors; Receptors, Cell Surface; Receptors, Purinergic; Respiration; Seizures; SRS-A; Theophylline; Vasoconstriction; Vasodilation; Xanthines | 1986 |
2 trial(s) available for caffeine and enprofylline
| Article | Year |
|---|---|
Cardiovascular effects of two xanthines and the relation to adenosine antagonism.
Topics: Adenosine; Adult; Aldosterone; Blood Pressure; Caffeine; Double-Blind Method; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Male; Nausea; Norepinephrine; Random Allocation; Renin; Xanthines | 1989 |
Respiratory stimulant effects of adenosine in man after caffeine and enprofylline.
Topics: Adenosine; Adult; Bronchodilator Agents; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Respiration; Respiratory Function Tests; Stimulation, Chemical; Xanthines | 1987 |
20 other study(ies) available for caffeine and enprofylline
| Article | Year |
|---|---|
Imidazodiazepinediones: a new class of adenosine receptor antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Azepines; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diazepam; Imidazoles; In Vitro Techniques; Molecular Conformation; Phenylisopropyladenosine; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1990 |
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines | 1989 |
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines | 2002 |
Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists.
Topics: 3T3 Cells; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Brain; Electrophoresis, Capillary; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; In Vitro Techniques; Membranes; Mice; PC12 Cells; Purinergic P1 Receptor Antagonists; Purines; Purinones; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Solubility; Stereoisomerism; Structure-Activity Relationship; Water | 2002 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.
Topics: Adenosine A2 Receptor Antagonists; Animals; Drug Design; Humans; Kinetics; Ligands; Mice; Protein Binding; Radioligand Assay; Rats; Receptor, Adenosine A2B; Xanthines | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery of Potent and Highly Selective A2B Adenosine Receptor Antagonist Chemotypes.
Topics: Adenosine A2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Pyrimidinones; Receptor, Adenosine A2B; Structure-Activity Relationship | 2016 |
Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Caffeine; Electroencephalography; Male; Parasympatholytics; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Theophylline; Xanthines | 1992 |
Peripheral mechanisms of thermogenesis induced by ephedrine and caffeine in brown adipose tissue.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature Regulation; Caffeine; Culture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Ephedrine; Male; Oxygen Consumption; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Theophylline; Xanthines | 1991 |
Caffeine and theophylline attenuate adenosine-induced vasodilation in humans.
Topics: Adenosine; Adolescent; Adult; Bronchodilator Agents; Caffeine; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Regional Blood Flow; Theophylline; Vasodilation; Xanthines | 1990 |
Activities of caffeine, theophylline, and enprofylline analogs as tracheal relaxants.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Receptors, Purinergic; Theophylline; Trachea; Xanthines | 1990 |
Simple and sensitive method for the simultaneous determination of enprofylline, theobromine, paraxanthine, theophylline and caffeine using high-performance liquid chromatography.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Theobromine; Theophylline; Xanthines | 1986 |
Methylxanthines reduce in vitro human overall platelet metabolism as measured by microcalorimetry.
Topics: Blood Platelets; Body Temperature Regulation; Caffeine; Calorimetry; Humans; Theophylline; Xanthines | 1986 |
Effects of alkylxanthines on contractility of diaphragm fibres isolated from normal and sensitized guinea-pigs.
Topics: Adenosine; Animals; Bronchodilator Agents; Caffeine; Calcium; Culture Media; Dantrolene; Diaphragm; Electric Stimulation; Extracellular Space; Female; Guinea Pigs; Immunization; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Serum Albumin, Bovine; Theobromine; Theophylline; Verapamil; Xanthines | 1993 |
Convulsant effects of some xanthine derivatives in genetically epilepsy-prone rats.
Topics: 1-Methyl-3-isobutylxanthine; Acoustic Stimulation; Animals; Caffeine; Convulsants; Dyphylline; Electroencephalography; Epilepsy; Female; Lipid Metabolism; Male; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Theobromine; Theophylline; Xanthines | 1997 |
Promotion of forskolin-induced long-term potentiation of synaptic transmission by caffeine in area CA1 of the rat hippocampus.
Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Colforsin; Cyclic AMP; Drug Synergism; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Quinazolines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazoles; Xanthines | 1999 |