caffeine has been researched along with dapsone in 35 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.86) | 18.7374 |
1990's | 3 (8.57) | 18.2507 |
2000's | 12 (34.29) | 29.6817 |
2010's | 19 (54.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Hein, DW; Weber, WW | 1 |
Guo, R; Lauterberg, B; Thormann, W | 1 |
Adedoyin, A; Branch, RA; Frye, RF; Matzke, GR; Porter, JA | 1 |
Adedoyin, A; Branch, RA; Frye, RF; Mauro, K | 1 |
Crane, LR; Doll, MA; Drobitch, RK; Farrough, MJ; Fretland, AJ; Hein, DW; MacArthur, RD; O'Neil, WM; Svensson, CK | 1 |
Adedoyin, A; Branch, RA; Frye, RF; Romkes, M; Wilson, JW | 1 |
Branch, RA; Frye, RF | 1 |
Hu, JP; Xu, YX; Yan, SL; Zhang, JN | 1 |
Arsenault, M; Bélanger, PM; Hamelin, BA; Pilote, S; Sharma, A | 1 |
Branch, RA; Frye, RF; Romkes, M; Tracy, TS; Zgheib, NK | 1 |
Ge, B; Jiang, S; Li, Y; Liu, X; Min, G; Tang, H | 1 |
Gao, J; Gao, X; Jia, H; Xu, A; Yuan, J | 1 |
Guo, K; Ji, H; Jiang, SX; Zhang, JR; Zhang, LL; Zhang, Y | 1 |
Jiang, SX; Mo, F; Yu, ZG; Zhang, JR; Zhang, LL; Zhao, J | 1 |
Hang, P; Liu, G; Liu, R; Liu, Y; Qin, M; Zhang, Z | 1 |
Li, X; Liu, G; Liu, Y; Tai, S; Yang, C; Zhang, X | 1 |
Cui, J; Li, J; Li, R; Lin, W; Ling, X; Yang, H; Yu, N; Zhang, J | 1 |
Chang, ZQ; Li, J; Zhai, QQ | 1 |
Bhateria, M; Bhatta, RS; Ramakrishna, R; Singh, R | 1 |
Amaro, MI; Cabral, LM; da Silva, LCRP; de Almeida, GS; de Sousa, VP; do Amaral, LH; do Carmo, FA; Healy, AM; Rodrigues, CR | 1 |
Dong, M; Liu, D; Liu, G; Qiao, Y; Qin, M; Shi, Y; Xu, J; Zhang, W | 1 |
Cabral, LM; Healy, AM; Todaro, V; Worku, ZA | 1 |
2 review(s) available for caffeine and dapsone
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
N-acetylation pharmacogenetics.
Topics: Acebutolol; Acetyl Coenzyme A; Acetylation; Acetyltransferases; Aminoglutethimide; Animals; Anti-Anxiety Agents; Benzodiazepines; Caffeine; Carcinogens; Cricetinae; Dapsone; Disease; Drug-Related Side Effects and Adverse Reactions; Ethnicity; Genotype; Humans; Hydrazines; Kinetics; Liver; Mice; Models, Biological; Mutagens; Pharmaceutical Preparations; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Procainamide; Rabbits; Species Specificity; Substrate Specificity; Sulfasalazine | 1985 |
2 trial(s) available for caffeine and dapsone
Article | Year |
---|---|
Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes.
Topics: Adult; Analysis of Variance; Arylamine N-Acetyltransferase; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Interactions; Humans; Male; Mephenytoin; Phenotype; Reference Values | 1997 |
Validation of incorporating flurbiprofen into the Pittsburgh cocktail.
Topics: Administration, Oral; Adolescent; Adult; Aged; Caffeine; Chlorzoxazone; Cross-Over Studies; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Therapy, Combination; Female; Flurbiprofen; Genotype; Humans; Isoenzymes; Male; Mephenytoin; Middle Aged | 2006 |
31 other study(ies) available for caffeine and dapsone
Article | Year |
---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Relationship between high incidence of adverse dapsone reactions and slow acetylate phenotype or low plasma/lymphocyte glutathione level.
Topics: Acetylation; Acquired Immunodeficiency Syndrome; Adult; Anti-Infective Agents; Caffeine; Chromatography, High Pressure Liquid; Dapsone; Female; Glutathione; Humans; Lymphocytes; Male; Middle Aged; Phenotype | 1996 |
Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail.
Topics: Adult; Analysis of Variance; Antimalarials; Caffeine; Chloroquine; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Administration Schedule; Drug Interactions; Humans; Isoenzymes; Male; Phenotype | 1998 |
Acetylator phenotype and genotype in patients infected with HIV: discordance between methods for phenotype determination and genotype.
Topics: Acetylation; Adult; Antigens, CD; Arylamine N-Acetyltransferase; Base Sequence; Caffeine; Dapsone; DNA Primers; Female; Genotype; HIV Infections; Humans; Isoenzymes; Male; Middle Aged; Phenotype; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha | 2000 |
In vivo modulation of CYP enzymes by quinidine and rifampin.
Topics: Acetylation; Administration, Oral; Adrenergic alpha-Antagonists; Adult; Anti-Arrhythmia Agents; Antibiotics, Antitubercular; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Drug Administration Schedule; Enzyme Inhibitors; Humans; Male; Mephenytoin; Mixed Function Oxygenases; Quinidine; Reference Values; Rifampin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline | 2000 |
Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N-acetyltransferase in healthy human subjects.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Debrisoquin; Disulfiram; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Male; Mephenytoin; Mixed Function Oxygenases; Time Factors | 2002 |
[Simultaneous determination of three probe drugs by reversed-phase high performance liquid chromatography].
Topics: Animals; Caffeine; Chlorzoxazone; Chromatography, High Pressure Liquid; Dapsone; Male; Rats | 2002 |
A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study.
Topics: Adult; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Dapsone; Drug Combinations; Humans; Male; Metoprolol; Phenformin; Pilot Projects; Tolbutamide | 2004 |
Evaluation of protective effects of Chi-Zhi-Huang decoction on Phase I drug metabolism of liver injured rats by cocktail probe drugs.
Topics: Alanine Transaminase; Animals; Area Under Curve; Aspartate Aminotransferases; Bilirubin; Caffeine; Chemical and Drug Induced Liver Injury; Chlorzoxazone; Chromatography, High Pressure Liquid; Dapsone; Drugs, Chinese Herbal; Liver; Liver Function Tests; Male; Plants, Medicinal; Protective Agents; Rats; Rats, Wistar | 2008 |
[Experimental study on cytochrome P450 enzymes after receiving ferment powder caterpillar fungus].
Topics: Animals; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Drugs, Chinese Herbal; Fermentation; Male; Random Allocation; Rats; Rats, Wistar | 2009 |
Effects of fluoroquinolones on CYP4501A and 3A in male broilers.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Caffeine; Chickens; Ciprofloxacin; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Drug Interactions; Enrofloxacin; Fluoroquinolones; Gene Expression Regulation, Enzymologic; Half-Life; Liver; Male; Organ Size; Weight Gain | 2011 |
Effects of ionophores on liver CYP1A and 3A in male broilers.
Topics: Animals; Blotting, Western; Caffeine; Chickens; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Dapsone; Dose-Response Relationship, Drug; Gene Expression; Ionophores; Lactones; Liver; Male; Microsomes, Liver; Monensin; Pyrans; Reverse Transcriptase Polymerase Chain Reaction; RNA Processing, Post-Transcriptional; RNA, Messenger | 2010 |
Effects of Panax notoginseng saponins on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats in vivo.
Topics: Animals; Blotting, Western; Caffeine; Chromatography, Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochromes; Dapsone; Enzyme Activation; Injections, Intraperitoneal; Liver; Male; Metoprolol; Panax notoginseng; Protein Biosynthesis; Rats; Rats, Wistar; Saponins; Tandem Mass Spectrometry; Time Factors; Tolbutamide | 2012 |
UPLC-MS-MS method for simultaneous determination of caffeine, tolbutamide, metoprolol, and dapsone in rat plasma and its application to cytochrome P450 activity study in rats.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dapsone; Drug Stability; Linear Models; Male; Metoprolol; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tolbutamide | 2013 |
Evaluation of the effect of TM208 on the activity of five cytochrome P450 enzymes using on-line solid-phase extraction HPLC-DAD: a cocktail approach.
Topics: Administration, Oral; Animals; Antipyrine; Caffeine; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dapsone; Limit of Detection; Linear Models; Male; Metoprolol; Omeprazole; Piperazines; Random Allocation; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Solid Phase Extraction | 2013 |
Evaluation on activity of cytochrome p450 enzymes in turbot via a probe drug cocktail.
Topics: Animals; Antitubercular Agents; Area Under Curve; Caffeine; Chlorzoxazone; Cytochrome P-450 Enzyme System; Dapsone; Enzyme Induction; Flatfishes; Folic Acid Antagonists; Muscle Relaxants, Central; Nucleic Acid Synthesis Inhibitors; Phosphodiesterase Inhibitors; Rifampin | 2014 |
Evaluation of the impact of 16-dehydropregnenolone on the activity and expression of rat hepatic cytochrome P450 enzymes.
Topics: Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P450 Family 2; Dapsone; Dextromethorphan; Gene Expression Regulation; Hypolipidemic Agents; Liver; Male; Microsomes, Liver; Pregnenolone; Rats; Rats, Sprague-Dawley; Steroid 16-alpha-Hydroxylase; Tolbutamide | 2016 |
Development and Characterization of Dapsone Cocrystal Prepared by Scalable Production Methods.
Topics: Administration, Inhalation; Caffeine; Calorimetry, Differential Scanning; Cell Line; Chemistry, Pharmaceutical; Crystallization; Dapsone; Desiccation; Drug Compounding; Dry Powder Inhalers; Humans; Microscopy, Electron, Scanning; Particle Size; Solubility; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; X-Ray Diffraction | 2018 |
Effects of shuanghuanglian injection on the activities of CYP1A2, 2C11, 2D1 and 3A1/2 in rats in vivo and in vitro.
Topics: Animals; Caffeine; Calibration; Cytochrome P-450 Enzyme System; Dapsone; Drugs, Chinese Herbal; Injections; Limit of Detection; Male; Metabolome; Metoprolol; Rats, Wistar; Reproducibility of Results; Time Factors; Tolbutamide | 2019 |
In Situ Cocrystallization of Dapsone and Caffeine during Fluidized Bed Granulation Processing.
Topics: Caffeine; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Dapsone; Drug Combinations; Solvents; X-Ray Diffraction | 2019 |