caffeine and dactinomycin

caffeine has been researched along with dactinomycin in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199030 (71.43)18.7374
1990's2 (4.76)18.2507
2000's3 (7.14)29.6817
2010's7 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Götz von Olenhusen, KG; Jücker, H; Wohlfarth-Bottermann, KE1
Claycomb, WC1
Clarke, CH; Shankel, DM1
Dewey, WC; Tomasovic, SP1
Kohn, KW; Ross, WE; Zwelling, LA1
Chubykin, VL; Lebedeva, LI1
Allewell, NM; Oles, J; Wolfe, J1
Aĭrapetian, LG; Sevan'kaev, AV1
Belyaeva, ES; Semeshin, VF; Sherudilo, AI1
Sancar, A; Selby, CP1
Craig, RW; Kastan, MB; Onyekwere, O; Sidransky, D; Vogelstein, B1
Pardee, AB; Schlegel, R1
Johnson, MD; Lambert, ME; Okin, E; Ronai, ZA; Weinstein, IB1
Delbono, O; Muchnik, S; Obejero Paz, CA1
Ono, J; Shimazu, Y1
Davies, DR1
Arlett, CF2
Cleaver, JE1
Oliver, IT; Yeung, D1
Fukui, N1
Sasaki, MS; Tonomura, A1
Kiefer, J1
Bootsma, D; Hoeksema, JL; Kleijer, WJ; Sluyter, ML1
Jeter, WS; Klesius, PH; Laux, DC1
Oravec, M; Sourkes, TL; Young, SN1
Rahwan, RG1
Nishikawa, H; Shio, I1
Dehn, F; LeValley, SE; Lombrozo, L; Mitoma, C1
Best, JB; Morita, M1
Kleppe, K; Lossius, I; Sandlie, I; Sjåstad, K1
Mathinos, PR; Randall, JL; Ritter, EJ; Scott, WJ; Wilson, JG1
Bedner, E; Darzynkiewicz, Z; Du, L; Traganos, F1
Huseby, NE; Johannessen, M; Moens, U; Pandur, S; Pankiv, S1
Goodisman, J; Jones, E; Souid, AK; Tao, Z1
Ma, H; Pederson, T1
Kovalev, VI; Vekshin, NL1

Reviews

4 review(s) available for caffeine and dactinomycin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antimutagenesis in microbial systems.
    Bacteriological reviews, 1975, Volume: 39, Issue:1

    Topics: Acridines; Antipsychotic Agents; Bacteria; Caffeine; Chloramphenicol; Dactinomycin; Dibenzocycloheptenes; DNA Repair; Escherichia coli; Fungi; Genes; Histidine; Manganese; Mutagens; Mutation; Phenothiazines; Polyamines; Purine Nucleosides; Quinacrine; Radiation Effects; Rosaniline Dyes; Ultraviolet Rays; Uracil; Warfarin

1975
The biochemical and pharmacological basis of learning and memory.
    Agents and actions, 1971, Volume: 2, Issue:3

    Topics: Amphetamine; Azaguanine; Brain Chemistry; Caffeine; Cycloheximide; Dactinomycin; Glutamates; Learning; Memory; Memory, Short-Term; Nerve Tissue Proteins; Neurons; Pemoline; Puromycin; Quaternary Ammonium Compounds; RNA; Strychnine; Time Factors; Vitamin B 12

1971
Planarians as a model system for in vitro teratogenesis studies.
    Teratogenesis, carcinogenesis, and mutagenesis, 1982, Volume: 2, Issue:3-4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Behavior, Animal; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cadmium; Caffeine; Chlordan; Colchicine; Dactinomycin; Demecolcine; Drug Evaluation, Preclinical; Ethanol; Lead; Mercury; Models, Biological; Planarians; Puromycin; Reproduction; Teratogens; Thalidomide; Turbellaria

1982

Other Studies

38 other study(ies) available for caffeine and dactinomycin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Induction of a plasmodial stage of Physarum without plasmalemma invaginations.
    Cell and tissue research, 1979, Apr-12, Volume: 197, Issue:3

    Topics: Caffeine; Cell Membrane; Cytoplasm; Cytoskeleton; Dactinomycin; Microscopy, Electron; Movement; Physarum; Time Factors

1979
Poly(adenosine diphosphate ribose) polymerase activity and nicotinamide adenine dinucleotide in differentiating cardiac muscle.
    The Biochemical journal, 1976, Feb-15, Volume: 154, Issue:2

    Topics: Adenosine Triphosphate; Animals; Bucladesine; Caffeine; Cell Differentiation; Cell Nucleus; Dactinomycin; DNA; DNA Nucleotidyltransferases; Heart; Isoproterenol; Myocardium; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Niacinamide; Proteins; Rats; Theophylline; Thymidine; Xanthines

1976
Comparative studies of the effects of drugs on X-ray-induced G2 delay.
    Radiation research, 1978, Volume: 74, Issue:1

    Topics: Benzimidazoles; Caffeine; Cell Cycle; Cells, Cultured; Dactinomycin; Deoxyadenosines; Dimethyl Sulfoxide; Lucanthone; Mitosis; RNA; Sulfhydryl Compounds; Theophylline; Time Factors; X-Rays

1978
Relationship between cytotoxicity and DNA strand breakage produced by adriamycin and other intercalating agents.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:8

    Topics: Animals; Caffeine; Cell Survival; Cells, Cultured; Dactinomycin; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Doxorubicin; Drug Interactions; Ellipticines; Intercalating Agents; Leukemia L1210; Mice

1979
[Formation of structural chromosome mutations in metaphase of mitosis].
    Genetika, 1979, Volume: 15, Issue:3

    Topics: Acridine Orange; Animals; Caffeine; Cells, Cultured; Chromosome Aberrations; Chromosomes; Dactinomycin; Ethidium; Fibroblasts; Hydroxylamines; Metaphase; Mice; Mice, Inbred BALB C; Mutation; Puromycin; Ultraviolet Rays

1979
A physicochemical analysis of conjugation in Tetrahymena pyriformis.
    Experimental cell research, 1976, Volume: 97, Issue:2

    Topics: Amino Acids; Animals; Caffeine; Calcium; Colchicine; Conjugation, Genetic; Culture Media; Cycloheximide; Dactinomycin; Dithiothreitol; Egtazic Acid; Kinetics; Magnesium; Manganese; Potassium; Sodium; Temperature; Tetrahymena pyriformis; Theophylline; Zinc

1976
[Action of caffeine and actinomycin D on the frequency of chromosome aberrations in a human lymphocyte culture after irradiation at various stages of the cell cycle].
    Meditsinskaia radiologiia, 1977, Volume: 22, Issue:2

    Topics: Caffeine; Cells, Cultured; Chromosome Aberrations; Dactinomycin; Gamma Rays; Humans; Lymphocytes; Mitosis; Time Factors

1977
Nucleoli formation under inhibited RNA synthesis.
    Experimental cell research, 1975, Volume: 93, Issue:2

    Topics: Caffeine; Cell Line; Cell Nucleolus; Cell Nucleus; Dactinomycin; Diploidy; Dose-Response Relationship, Drug; Mitosis; RNA

1975
Noncovalent drug-DNA binding interactions that inhibit and stimulate (A)BC excinuclease.
    Biochemistry, 1991, Apr-23, Volume: 30, Issue:16

    Topics: Binding Sites; Bisbenzimidazole; Caffeine; Dactinomycin; DNA; DNA Repair; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Ethidium; Intercalating Agents; Kinetics; Plasmids; Protein Binding

1991
Participation of p53 protein in the cellular response to DNA damage.
    Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 1

    Topics: Bone Marrow Cells; Caffeine; Cell Cycle; Cycloheximide; Dactinomycin; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; Exons; Flow Cytometry; Genes, p53; Humans; Mutation; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1991
Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells.
    Science (New York, N.Y.), 1986, Jun-06, Volume: 232, Issue:4755

    Topics: Animals; Caffeine; Cells, Cultured; Cricetinae; Cycloheximide; Dactinomycin; DNA Replication; Interphase; Mitosis; RNA

1986
Induction of asynchronous replication of polyoma DNA in rat cells by ultraviolet irradiation and the effects of various inhibitors.
    Cancer research, 1987, Sep-01, Volume: 47, Issue:17

    Topics: Animals; Base Sequence; Caffeine; Cell Line; Cycloheximide; Dactinomycin; DNA; DNA Damage; DNA Replication; Polyomavirus; Rats; Ultraviolet Rays; Virus Replication

1987
Effects of actinomycin D on contractile properties of denervated rat skeletal muscle.
    Experimental neurology, 1986, Volume: 94, Issue:3

    Topics: Animals; Caffeine; Dactinomycin; Membrane Potentials; Muscle Contraction; Muscle Denervation; Muscles; Organ Size; Rats; Rats, Inbred Strains

1986
Ultraviolet reactivation of a bacteriophage containing a single-stranded deoxyribonucleic acid as a genetic element.
    Virology, 1966, Volume: 29, Issue:2

    Topics: Caffeine; Chloramphenicol; Coliphages; Dactinomycin; DNA, Viral; In Vitro Techniques; Radiation Effects; Ultraviolet Rays

1966
Repair mechanisms and variations in UV sensitivity within the cell cycle.
    Mutation research, 1965, Volume: 2, Issue:6

    Topics: Acridines; Caffeine; Cell Division; Chloramphenicol; Dactinomycin; DNA; Eukaryota; Light; Radiation Genetics; Ultraviolet Rays

1965
A failure of specific inhibitors to affect survival of Chinese hamster cells exposed to ultra-violet light.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1967, Volume: 13, Issue:4

    Topics: Acridines; Animals; Caffeine; Chloramphenicol; Clone Cells; Cricetinae; Cycloheximide; Dactinomycin; Puromycin; Radiation Effects; Theophylline; Ultraviolet Rays

1967
Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair.
    Radiation research, 1969, Volume: 37, Issue:2

    Topics: Acridines; Animals; Autoradiography; Bromodeoxyuridine; Caffeine; Centrifugation, Density Gradient; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Depression; DNA; DNA Replication; Floxuridine; Gentian Violet; HeLa Cells; Humans; Hydroxyurea; Iodoacetates; L Cells; Mice; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays

1969
Induction of phosphopyruvate carboxylase in neonatal rat liver by adenosine 3',5'-cyclic monophosphate.
    Biochemistry, 1968, Volume: 7, Issue:9

    Topics: Adenine Nucleotides; Animals; Animals, Newborn; Caffeine; Carboxy-Lyases; Cyclic AMP; Dactinomycin; Enzyme Induction; Ergotamine; Fetus; Fructose-Bisphosphatase; Insulin; Liver; Nitrogen; Nucleotides; Prostaglandins; Pyruvate Kinase; Pyruvates; Radioisotopes; Rats

1968
Factors regulating thymidine kinase in regenerating liver.
    Journal of biochemistry, 1971, Volume: 69, Issue:6

    Topics: Adrenocorticotropic Hormone; Animals; Caffeine; Carbon Isotopes; Cyclic AMP; Cycloheximide; Dactinomycin; DNA Replication; Female; Growth Hormone; Hepatectomy; Hypophysectomy; In Vitro Techniques; Liver; Liver Regeneration; Rats; Thymidine; Thymidine Kinase; Tritium

1971
A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.
    Cancer research, 1973, Volume: 33, Issue:8

    Topics: Alkanesulfonates; Alkylating Agents; Anemia, Aplastic; Antimetabolites; Caffeine; Cell Division; Cells, Cultured; Chloramphenicol; Chromosome Aberrations; Chromosomes; Cobalt Isotopes; Dactinomycin; DNA Repair; Humans; Lymphocytes; Mechlorethamine; Methoxsalen; Mitomycins; Nitrosoguanidines; Quinolines; Radiation Effects; Ultraviolet Rays

1973
The effect of some nucleic acid-binding metabolic inhibitors on split-dose sparing in u.v.-and electron-irradiated diploid yeast.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1973, Volume: 24, Issue:1

    Topics: Acridines; Anaerobiosis; Caffeine; Dactinomycin; Diploidy; DNA Repair; Electrons; Formaldehyde; Hydroxylamines; Radiation Dosage; Radiation Effects; Saccharomyces cerevisiae; Ultraviolet Rays

1973
Effects of inhibitors on repair of DNA in normal human and xeroderma pigmentosum cells after exposure to x-rays and ultraviolet irradiation.
    Mutation research, 1973, Volume: 17, Issue:3

    Topics: Acridines; Anti-Bacterial Agents; Caffeine; Cells, Cultured; Dactinomycin; Dinitrophenols; DNA; DNA Repair; Edetic Acid; Fibroblasts; Gentian Violet; HeLa Cells; Humans; Iodoacetates; Kidney; Potassium; Radiation Dosage; Ultraviolet Rays; Xeroderma Pigmentosum

1973
Suppressive effects of caffeine on the immune response of the mouse to sheep erythrocytes.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 144, Issue:2

    Topics: Animals; Antibody Formation; Caffeine; Carbon Radioisotopes; Cells, Cultured; Dactinomycin; Depression, Chemical; DNA; Erythrocytes; Hemolysin Proteins; Immunization; Immunosuppressive Agents; Isoleucine; Mice; Protein Biosynthesis; Puromycin; Sheep; Spleen; Thymidine; Tritium; Uridine

1973
The effect of theophylline on tryptophan pyrrolase in the hypophysectomized rat and some observations on the validity of tryptophan pyrrolase assays.
    The Journal of biological chemistry, 1974, Jun-25, Volume: 249, Issue:12

    Topics: Animals; Caffeine; Carbon Dioxide; Carbon Radioisotopes; Chromatography, Paper; Cycloheximide; Dactinomycin; Enzyme Activation; Hydrocortisone; Hypophysectomy; Kinetics; Liver; Male; Models, Chemical; Perfusion; Pituitary Gland; Rats; Theophylline; Tryptophan; Tryptophan Oxygenase

1974
Effect of caffeine on adenylosuccinate lyase synthesis in Bacillus subtilis.
    Journal of biochemistry, 1969, Volume: 65, Issue:4

    Topics: Bacillus subtilis; Caffeine; Culture Media; Dactinomycin; Lyases; Nucleosides; Nucleotides; Oxidoreductases; Puromycin; Succinates; Theobromine; Theophylline; Time Factors; Transferases; Xanthines

1969
The influence of post-irradiation conditions on the survival of Chinese hamster cells after gamma-irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1970, Volume: 17, Issue:6

    Topics: Acridines; Animals; Caffeine; Chloramphenicol; Cricetinae; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; Hydroxylamines; Hydroxyurea; Protein Binding; Protein Biosynthesis; Puromycin; Radiation Effects; Temperature; Thymidine

1970
Nature of the effect of caffeine on the drug-metabolizing enzymes.
    Archives of biochemistry and biophysics, 1969, Volume: 134, Issue:2

    Topics: 17-Hydroxycorticosteroids; Acetanilides; Amino Acids; Aminopyrine; Aniline Compounds; Animals; Caffeine; Cytochromes; Dactinomycin; Drug Antagonism; Enzyme Induction; Female; Humans; Male; Methylation; Microsomes, Liver; Oxidoreductases; Phenobarbital; Pregnanes; Pyridones; Rats; Stimulation, Chemical; Time Factors; Zoxazolamine

1969
Mechanism of caffeine-induced inhibition of DNA synthesis in escherichia coli.
    FEBS letters, 1983, Jan-24, Volume: 151, Issue:2

    Topics: Caffeine; Dactinomycin; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; Kinetics; Nalidixic Acid; Novobiocin

1983
Potentiative interactions between caffeine and various teratogenic agents.
    Teratology, 1982, Volume: 25, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Caffeine; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Emetine; Female; Fetal Death; Floxuridine; Hydroxyurea; Pregnancy; Rats; Rats, Inbred Strains

1982
Caffeine dissociates complexes between DNA and intercalating dyes: application for bleaching fluorochrome-stained cells for their subsequent restaining and analysis by laser scanning cytometry.
    Cytometry, 2001, Jan-01, Volume: 43, Issue:1

    Topics: Caffeine; Dactinomycin; DNA; Electrophoresis, Agar Gel; Flow Cytometry; Fluorescence; Fluorescent Dyes; HL-60 Cells; Humans; Intercalating Agents; Kinetics; Lasers; Models, Chemical; Propidium; Staining and Labeling

2001
Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells.
    Free radical research, 2007, Volume: 41, Issue:12

    Topics: Animals; Caffeine; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Cycloheximide; Dactinomycin; gamma-Glutamylcyclotransferase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Oxidative Stress; ras Proteins; Rats; RNA, Messenger; Signal Transduction; Vitamin K 3

2007
Quantitative measure of cytotoxicity of anticancer drugs and other agents.
    Analytical biochemistry, 2008, Oct-01, Volume: 381, Issue:1

    Topics: Antineoplastic Agents; Caffeine; Cell Death; Cell Respiration; Cyclosporine; Dactinomycin; Doxorubicin; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Jurkat Cells; Platinum Compounds; Tirapazamine; Triazines

2008
The nucleolus stress response is coupled to an ATR-Chk1-mediated G2 arrest.
    Molecular biology of the cell, 2013, Volume: 24, Issue:9

    Topics: Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle Proteins; Cell Nucleolus; Checkpoint Kinase 1; Dactinomycin; DNA Damage; G2 Phase Cell Cycle Checkpoints; HeLa Cells; Histones; Humans; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Single-Cell Analysis; Stress, Physiological

2013
Nucleotide carriers for anti-tumour actinomycin antibiotics.
    Journal of biochemistry, 2016, Volume: 159, Issue:1

    Topics: Adenine; Antibiotics, Antineoplastic; Caffeine; Dactinomycin; DNA; Drug Carriers; Fluorescent Dyes; Folic Acid; Guanine; Nucleotides; Thymine

2016