caffeine and cyclic gmp

caffeine has been researched along with cyclic gmp in 102 studies

Research

Studies (102)

Timeframe	Studies, this research(%)	All Research%
pre-1990	52 (50.98)	18.7374
1990's	35 (34.31)	18.2507
2000's	11 (10.78)	29.6817
2010's	4 (3.92)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Morishima, I	2
Chatterjee, SK; Kim, U	1
Filburn, CR; Karn, J; Wyatt, GR	1
Collier, HO	1
Chan, YH; Curtis-Prior, PB; Gibbons, JR	1
Singh, M	1
Howell, SL; Montague, W; Tyhurst, M	1
Dickens, MS; Lucas-Leonard, J; Roth, JS	1
Chu, EH; Trosko, JE	1
Furihata, C; Matsushima, T; Sugimura, T; Terai, M	1
Erlij, D; Grinstein, S	1
Asano, T; Hidaka, H; Ochiai, Y	1
Heim, F; Mitznegg, P; Sprügel, W	1
Roberts, JJ; Tisdale, MJ	1
Coosen, R; Geilenkirchen, WL; Jansen, J; van Wijk, R	1
Foecking, MK; Matthews, RH; Minton, JP; Webster, DJ	1
Bianchi, CP	1
Stefanovich, V	1
Perlman, RL; Ullman, B	1
Huang, TF; Ko, FN; Liou, MJ; Teng, CM; Wu, TS	1
Huang, LJ; Huang, TF; Kuo, SC; Sun, SS; Teng, CM; Yu, SM	1
Huang, TF; Ko, FN; Lin, CN; Liou, SS; Teng, CM	1
Huang, TF; Ko, FN; Teng, CM	1
Frings, S; Lindemann, B	1
Hester, RK; Koibuchi, Y; Matsuo, M; Satake, N; Sato, N; Shibata, S	1
Fontana, DR; Luo, CS; Phillips, JC	1
Chen, CC; Huang, TF; Huang, YL; Lin, CH; Teng, CM; Tsai, CW; Yu, SM	1
Bolton, TB; Komori, S	1
Ivanov, AI; Ivanova, TN; Korovkin, BF; Losev, NI	1
Kai, H; Kanaide, H; Nakamura, M	1
Twort, CH; van Breemen, C	1
Adam-Vizi, V; Allen, TJ; Baker, PF	1
Itoh, T; Kanmura, Y; Kuriyama, H; Sasaguri, T	1
Obara, K; Yamada, T	1
Higgins, WJ	1
Brush, JS; Kitabchi, AE; Solomon, SS	1
Kitabchi, AE; Sharma, RK; Wilson, DB	1
Fleischman, DE; Pannbacker, RG; Reed, DW	1
Cheung, WY; Song, SY	1
Murad, F; Pak, CY	1
Chasin, M; Harris, DN; Hess, SM; Phillips, MB	1
Murad, F	1
March, RB; Rojakovick, AS	1
Barnabei, O; Luly, P; Tomasi, V; Trevisani, A; Tria, E	1
Amrhein, N; Fischer, U	1
Gee, JB; Khandwala, AS	1
Cheung, WY; Lin, YM; Liu, YP	1
Bensinger, R; Chader, G; Fletcher, R; Johnson, M	1
Lackie, JM	1
Abramowitz, J; Chavin, W	1
Bittar, EE; Hift, H; Huddart, H; Tong, E	1
Kramer, GL; Wells, JN	1
Daniel, JW; Oleinick, NL	2
Kavaliers, M	1
Dascombe, MJ; Milton, AS	1
Anderson, P; Goldspink, DF; Lewis, SE	1
Brenner, M; Thoms, SD	1
Alsina, A; Debs-Elías, N; Rodríguez-Del Valle, N	1
Hatano, Y; Iranami, H; Mizumoto, K; Yamamoto, M; Yoshiyama, T	1
Bereta, J; Bereta, M; Coffman, FD; Cohen, MC; Cohen, S; Georgoff, I	1
Usachev, Y; Verkhratsky, A	1
Furukawa, K; Momose, K; Ohizumi, Y; Yamamoto, M; Yoshikawa, K	1
Ko, FN; Lu, ST; Teng, CM; Wu, YC	1
Garfield, RE; Izumi, H; Makino, Y; Shirakawa, K	1
Hsu, KS; Lin-Shiau, SY	2
Barker, JL; Bulan, EJ; Mienville, JM	1
Chen, WY; Ko, FN; Lu, ST; Teng, CM; Wu, YC	1
Koide, T; Naitoh, S; Sugawa, M; Tamura, K	1
Clementi, E; Meldolesi, J; Nisticò, G; Riccio, M; Sciorati, C	1
Grégoire, G; Loirand, G; Pacaud, P	1
Camello, PJ; Petersen, OH; Toescu, EC	1
García de Boto, MJ; Hidalgo, A; Menéndez, L; Sánchez, M	1
Johnson, DE; Kannan, MS; Prakash, YS; Sieck, GC	1
Hensel, M; Kox, WJ; Mäding, K; Volk, T	1
Kanaide, H; Kawasaki, J; Kobayashi, S; Nishimura, J; Sumiyoshi, R; Takahashi, S	1
Izumi, M; Karaki, H; Mitsui-Saito, M; Ozaki, H	1
Abe, K; Inoue, R; Ito, Y; Morita, H; Teramoto, N; Waniishi, Y	1
Hata, F; Ishii, T; Nishio, H; Saitoh, N; Sunami, O; Takeuchi, T	1
Aardal, S; Helle, KB; Lillestłl, IK	1
Dasso, M; Rosenzweig, S; Spielman, AI; Yan, W	1
Corbin, JD; Francis, SH	1
Aguirre-Bañuelos, P; Castañeda-Hernández, G; Granados-Soto, V; López-Muñoz, FJ	1
Cantoni, O; Clementi, E; Guidarelli, A; Sciorati, C	1
Cocks, TM; Selemidis, S	1
Castañeda-Hernández, G; Granados-Soto, V	1
Christophersen, P; Jensen, BS; Olesen, SP; Schrøder, RL; Strøbaek, D	1
Steinbusch, HW	1
Aalkjaer, C; Ivarsen, A; Matchkov, V; Nilsson, H; Peng, H	1
Bourreau, JP; Deng, C; Shan, Q; Yin, X	1
Conklin, JL; Cullen, JJ; Hinkhouse, MM; Lindaman, BA	1
Lehrman, MA; Shang, J	1
Lin, CH; Tsai, MC	1
Ahn, DS; Chung, SS; Lee, HG; Lee, YH; Nam, TS	1
Cao, LH; Yang, XL; Yu, YC	1
Bonz, A; Burkard, N; Cartwright, EJ; Frantz, S; Hallhuber, M; Hofmann, U; Hu, K; Kaufmann, SG; Maier, LS; Maier, SK; Neyses, L; Renné, T; Ritter, O; Rokita, AG; Schuh, K; Wu, R	1
Bian, JS; Hu, LF; Huang, D; Wang, S; Yong, QC	1
Bazán-Perkins, B	1
Arendash, GW; Bradshaw, PC; Cao, C; Copes, N; Delic, V; Dragicevic, N; Lin, X; Mamcarz, M; Wang, L	1
Aronsen, L; Lysaa, R; Orvoll, E; Ravna, AW; Sager, G	1

Reviews

5 review(s) available for caffeine and cyclic gmp

Article	Year
The role of DNA repair and somatic mutation in carcinogenesis. Advances in cancer research, 1975, Volume: 21 Topics: Aging; Base Sequence; Caffeine; Carcinogens; Cell Differentiation; Cell Division; Chromatin; Chromosome Aberrations; Cyclic AMP; Cyclic GMP; DNA Nucleotidyltransferases; DNA Repair; DNA Replication; Endonucleases; Environment; Genetic Diseases, Inborn; Humans; Models, Biological; Mutagens; Mutation; Neoplasms; Phenotype; Phorbol Esters; Precancerous Conditions; Recombination, Genetic; Ultraviolet Rays	1975
Clinical studies and applications of cyclic nucleotides. Advances in cyclic nucleotide research, 1973, Volume: 3 Topics: Affective Symptoms; Animals; Asthma; Caffeine; Calcitonin; Calcium; Catecholamines; Circadian Rhythm; Cyclic AMP; Cyclic GMP; Dermatitis, Atopic; Diabetes Insipidus; Glucagon; Growth Hormone; Humans; Hypercalcemia; Hyperparathyroidism; Hypocalcemia; Hypoparathyroidism; Insulin; Organ Specificity; Parathyroid Hormone; Psoriasis; Vasopressins	1973
Phosphodiesterase inhibitors as tools in cyclic nucleotide research: a precautionary comment. Molecular and cellular endocrinology, 1981, Volume: 23, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Cyclic AMP; Cyclic GMP; Isoenzymes; Phosphodiesterase Inhibitors; Theophylline; Xanthines	1981
Cyclic GMP phosphodiesterase-5: target of sildenafil. The Journal of biological chemistry, 1999, May-14, Volume: 274, Issue:20 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Hemodynamics; Humans; Male; Models, Chemical; Penis; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones	1999
A review of the pharmacokinetic and pharmacodynamic factors in the potentiation of the antinociceptive effect of nonsteroidal anti-inflammatory drugs by caffeine. Journal of pharmacological and toxicological methods, 1999, Volume: 42, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Humans	1999

Other Studies

97 other study(ies) available for caffeine and cyclic gmp

Article	Year
Cylic nucleotide phosphodiesterase in silkworm. Characterization of cyclic GMP phosphodiesterase. Biochimica et biophysica acta, 1975, Dec-18, Volume: 410, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Bombyx; Caffeine; Chromatography, Gel; Cyclic AMP; Cyclic GMP; Cyclic IMP; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Molecular Weight; Nucleotides; Phosphoric Diester Hydrolases; Theophylline	1975
Biochemical properties of cyclic nucleotide phosphodiesterase in metastasizing and nonmetastasizing rat mammary carcinomas. Journal of the National Cancer Institute, 1976, Volume: 56, Issue:1 Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Calcium; Cobalt; Cyclic AMP; Cyclic GMP; Depression, Chemical; Edetic Acid; Egtazic Acid; Hydrogen-Ion Concentration; Magnesium; Manganese; Neoplasm Metastasis; Nickel; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Theophylline; Zinc	1976
Cyclic nucleotide phosphodiesterases of Hyalophora cecropia silkmoth fat body. Biochimica et biophysica acta, 1977, Mar-15, Volume: 481, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Bombyx; Caffeine; Chromatography, Gel; Cyclic AMP; Cyclic GMP; Edetic Acid; Hot Temperature; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Larva; Manganese; Phosphoric Diester Hydrolases; Theophylline	1977
Consequences of interaction between opioid and receptor. Biochemical Society transactions, 1977, Volume: 5, Issue:1 Topics: Analgesics, Opioid; Animals; Brain; Caffeine; Cyclic AMP; Cyclic GMP; Drug Tolerance; Humans; Ileum; Models, Biological; Morphine; Neurons; Rats; Receptors, Opioid; Substance Withdrawal Syndrome; Substance-Related Disorders	1977
Cyclic nucleotide phosphodiesterase activity of human normal and carcinomatous lung tissue. Lancet (London, England), 1976, Dec-04, Volume: 2, Issue:7997 Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Caffeine; Carcinoma, Squamous Cell; Cyclic AMP; Cyclic GMP; Female; Humans; Lung; Lung Neoplasms; Middle Aged; Phosphoric Diester Hydrolases; Theophylline	1976
Calcium and cyclic nucleotide interaction in secretion of amylase from rat pancreas in vitro. The Journal of physiology, 1979, Volume: 296 Topics: Amylases; Animals; Bucladesine; Caffeine; Calcimycin; Calcium; Cholecystokinin; Cholera Toxin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Pancreas; Rats; Secretory Rate; Theophylline	1979
Calcium distribution in islets of Langerhans: a study of calcium concentrations and of calcium accumulation in B cell organelles. Journal of cell science, 1975, Volume: 19, Issue:2 Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Bucladesine; Caffeine; Calcium; Cell Nucleus; Cyclic AMP; Cyclic GMP; Cytoplasm; Cytoplasmic Granules; Endoplasmic Reticulum; Female; Islets of Langerhans; Mitochondria; Rats; Subcellular Fractions; Theophylline; Xanthines	1975
Induction of thymidylate synthetase activity in Tetrahymena by cyclic guanosine monophosphate. Biochemical and biophysical research communications, 1975, Dec-15, Volume: 67, Issue:4 Topics: Animals; Bucladesine; Caffeine; Cell Division; Culture Media; Cyclic GMP; Enzyme Induction; Methyltransferases; Tetrahymena pyriformis; Theophylline; Thymidylate Synthase	1975
Partial purification of adenosine 3',5'-cyclic monophosphate phosphodiesterases from rat pancreas in the presence of excess protease inhibitors. Archives of biochemistry and biophysics, 1976, Volume: 176, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Caffeine; Cyclic GMP; Cyclic IMP; Isoenzymes; Kinetics; Male; Pancreas; Phosphoric Diester Hydrolases; Protease Inhibitors; Rats; Theophylline	1976
Action of insulin and cell calcium: effect of ionophore A23187. The Journal of membrane biology, 1976, Nov-29, Volume: 29, Issue:4 Topics: Animals; Anti-Bacterial Agents; Bucladesine; Caffeine; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Insulin; Membrane Potentials; Methylglucosides; Muscle Contraction; Muscles; Rats; Theophylline	1976
Selective inhibition of separated forms of human platelet cyclic nucleotide phosphodiesterase by platelet aggregation inhibitors. Molecular pharmacology, 1977, Volume: 13, Issue:3 Topics: Adenosine; Blood Platelets; Caffeine; Chromatography, DEAE-Cellulose; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dipyridamole; Humans; In Vitro Techniques; Kinetics; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phthalazines; Platelet Aggregation; Theophylline	1977
The influence of caffeine and theobromine on locomotive activity and the brain cGMP/cAMP ratio in white mice. Biochemical pharmacology, 1977, Sep-15, Volume: 26, Issue:18 Topics: Animals; Brain Chemistry; Caffeine; Cyclic AMP; Cyclic GMP; Drug Interactions; Male; Mice; Motor Activity; Theobromine	1977
Cyclic nucleotide metabolism in HeLa and Chinese hamster cells after treatment with chlorambucil. Biochemical pharmacology, 1978, Feb-15, Volume: 27, Issue:4 Topics: Animals; Caffeine; Cell Line; Chlorambucil; Cricetinae; Cricetulus; Cyclic AMP; Cyclic GMP; Drug Synergism; HeLa Cells; Humans; Protein Kinases	1978
Changes in the content of cyclic AMP and cyclic GMP in eggs of Mactra solidissima during the second cleavage cycle. Cell biology international reports, 1977, Volume: 1, Issue:5 Topics: Animals; Caffeine; Cell Cycle; Cyclic AMP; Cyclic GMP; Female; Mitosis; Mollusca; Zygote	1977
Response of fibrocystic disease to caffeine withdrawal and correlation of cyclic nucleotides with breast disease. American journal of obstetrics and gynecology, 1979, Sep-01, Volume: 135, Issue:1 Topics: Adult; Breast Diseases; Caffeine; Cyclic AMP; Cyclic GMP; Cysts; Female; Humans; Middle Aged; Xanthines	1979
Regulation of aerobic metabolism of frog skeletal muscle by calcium, cyclic GMP and cyclic AMP. Proceedings of the Western Pharmacology Society, 1979, Volume: 22 Topics: Aerobiosis; Animals; Anura; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Muscles; Oxygen Consumption; Potassium	1979
Cyclic 3',5'-adenosine monophosphate phosphodiesterase (cAMP PDE) and cyclic 3',5'-guanosine monophosphate phosphodiesterase (cGMP PDE) in microvessels isolated from bovine cortex. Neurochemical research, 1979, Volume: 4, Issue:6 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Caffeine; Calcium; Cattle; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Imidazoles; Magnesium; Microcirculation; Theobromine; Theophylline	1979
Purification and characterization of a phosphoprotein phosphatase from bovine adrenal cortex. Biochimica et biophysica acta, 1975, Oct-22, Volume: 403, Issue:2 Topics: Adenine Nucleotides; Adrenal Cortex; Adrenal Glands; Animals; Caffeine; Cattle; Cyclic AMP; Cyclic GMP; Enzyme Activation; Fluorides; Hydrogen-Ion Concentration; Kinetics; Male; Manganese; Molecular Weight; Osmolar Concentration; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylase Phosphatase; Phosphorylases; Rats; Sodium Chloride	1975
Vasorelaxation of rat thoracic aorta caused by osthole isolated from Angelica pubescens. European journal of pharmacology, 1992, Aug-14, Volume: 219, Issue:1 Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Coumarins; Cyclic AMP; Cyclic GMP; Drugs, Chinese Herbal; Female; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Vasodilation	1992
Vasorelaxation of rat thoracic aorta caused by two Ca(2+)-channel blockers, HA-22 and HA-23. The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:8 Topics: Animals; Aorta, Thoracic; Benzopyrans; Caffeine; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Male; Nifedipine; Pyrans; Pyrazoles; Pyrroles; Rats; Rats, Inbred Strains; Vasodilation; Verapamil	1992
Vasorelaxation of rat thoracic aorta caused by norathyriol isolated from Gentianaceae. European journal of pharmacology, 1991, Jan-03, Volume: 192, Issue:1 Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Calcium Radioisotopes; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Inosine Monophosphate; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Plants, Medicinal; Potassium; Rats; Rats, Inbred Strains; Xanthenes	1991
Vasodilatory action mechanisms of apigenin isolated from Apium graveolens in rat thoracic aorta. Biochimica et biophysica acta, 1991, Nov-14, Volume: 1115, Issue:1 Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Calcium Radioisotopes; Chamomile; Cyclic AMP; Cyclic GMP; Female; Flavonoids; Inositol Phosphates; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oils, Volatile; Plants, Medicinal; Potassium; Rats; Rats, Inbred Strains; Vasodilator Agents	1991
Current recording from sensory cilia of olfactory receptor cells in situ. I. The neuronal response to cyclic nucleotides. The Journal of general physiology, 1991, Volume: 97, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Caffeine; Cilia; Colforsin; Cyclic AMP; Cyclic GMP; Electrophysiology; In Vitro Techniques; Nasal Mucosa; Phosphodiesterase Inhibitors; Rana esculenta; Rana ridibunda; Sensory Receptor Cells; Smell	1991
Characteristics of the vasorelaxing action of (3E)-4-ethyl-2-hydroximino-5-nitro-3-hexamide FK409, a new vasodilator isolated from microbial sources, in isolated rabbit arteries. Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:3 Topics: Animals; Arteries; Caffeine; Calcium; Cyclic GMP; Hemoglobins; Histamine; In Vitro Techniques; Inositol Phosphates; Male; Methylene Blue; Nitro Compounds; Nitroglycerin; Norepinephrine; Purinones; Rabbits; Serotonin; Vasoconstriction; Vasodilator Agents	1991
Dictyostelium discoideum lipids modulate cell-cell cohesion and cyclic AMP signaling. Molecular and cellular biology, 1991, Volume: 11, Issue:1 Topics: Adenylyl Cyclases; Caffeine; Cell Aggregation; Cell Communication; Cell Differentiation; Cell Membrane; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Membrane Lipids	1991
Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii. European journal of pharmacology, 1990, Oct-02, Volume: 187, Issue:1 Topics: Animals; Aorta, Thoracic; Benzofurans; Caffeine; Calcium; Calcium Radioisotopes; Cells, Cultured; Cyclic AMP; Cyclic GMP; Drugs, Chinese Herbal; Epoprostenol; In Vitro Techniques; Lignans; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Inbred Strains	1990
Actions of guanine nucleotides and cyclic nucleotides on calcium stores in single patch-clamped smooth muscle cells from rabbit portal vein. British journal of pharmacology, 1989, Volume: 97, Issue:3 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Caffeine; Calcium; Carbachol; Cyclic AMP; Cyclic GMP; Female; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Rabbits; Ryanodine	1989
[Acid hydrolase activity and cyclic nucleotide contents in the rat heart during myocardial ischemia and postischemic reperfusion]. Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 108, Issue:7 Topics: Acid Phosphatase; Animals; Caffeine; Cathepsin D; Coronary Disease; Cyclic AMP; Cyclic GMP; Male; Myocardial Reperfusion; Myocardium; Rats; Time Factors	1989
Effects of nicorandil on cytosolic calcium concentrations in quin2-loaded rat aortic vascular smooth muscle cells in primary culture. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:3 Topics: Aminoquinolines; Animals; Aorta; Caffeine; Calcium; Cells, Cultured; Cyclic GMP; Cytosol; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Vasodilator Agents	1989
Cyclic guanosine monophosphate-enhanced sequestration of Ca2+ by sarcoplasmic reticulum in vascular smooth muscle. Circulation research, 1988, Volume: 62, Issue:5 Topics: Animals; Caffeine; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Male; Muscle, Smooth, Vascular; Rats; Sarcoplasmic Reticulum	1988
The effects of nitroprusside and putative agonists on guanylate cyclase activity in squid giant axons. Biochimica et biophysica acta, 1988, Mar-03, Volume: 938, Issue:3 Topics: Animals; Axons; Caffeine; Carbachol; Cyclic GMP; Decapodiformes; Electric Stimulation; Ferricyanides; Glutamates; Glutamic Acid; Guanylate Cyclase; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Potassium Chloride; Serotonin	1988
Nitroglycerine- and isoprenaline-induced vasodilatation: assessment from the actions of cyclic nucleotides. British journal of pharmacology, 1985, Volume: 84, Issue:2 Topics: Animals; Bucladesine; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; Drug Interactions; Female; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Potassium; Protein Kinases; Rabbits; Swine; Vasodilation	1985
Changes in cyclic AMP and cyclic GMP levels in the contraction-relaxation cycle of isolated smooth muscle cells from guinea-pig taenia caeci. Nihon Heikatsukin Gakkai zasshi, 1985, Volume: 21, Issue:1 Topics: Animals; Caffeine; Colon; Cyclic AMP; Cyclic GMP; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Propranolol	1985
Intracellular actions of 5-hydroxytryptamine on the bivalve myocardium. 1. Adenylate and guanylate cyclases. The Journal of experimental zoology, 1974, Volume: 190, Issue:1 Topics: Acetylcholine; Adenylyl Cyclases; Animals; Bivalvia; Bucladesine; Caffeine; Cyclic AMP; Cyclic GMP; Dopamine; Guanylate Cyclase; Heart; Myocardium; Protein Binding; Serotonin; Stimulation, Chemical; Temperature; Theophylline; Tritium	1974
The insulin-like activity of cyclic nucleotides and their inhibition by caffeine on the isolated fat cells. Biochemical and biophysical research communications, 1970, Volume: 39, Issue:6 Topics: Adenine Nucleotides; Adipose Tissue; Butyrates; Caffeine; Carbon Dioxide; Carbon Isotopes; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Depression, Chemical; Glucose; Glycerol; In Vitro Techniques; Insulin; Insulin Antagonists; Lipid Metabolism; Lipids; Nucleotides; Stimulation, Chemical; Thymine Nucleotides; Uracil Nucleotides	1970
Steroidogenesis in isolated adrenal cells of rat. II. Effect of caffeine on ACTH and cyclic nucleotide-induced steroidogenesis and its relation to cyclic nucleotide phosphodiesterase (PDE). Biochemical and biophysical research communications, 1971, Aug-20, Volume: 44, Issue:4 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Butyrates; Caffeine; Corticosterone; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Drug Antagonism; Enzyme Activation; Imidazoles; In Vitro Techniques; Inosine Nucleotides; Phosphoric Monoester Hydrolases; Rats; Thymine Nucleotides; Tritium; Uracil Nucleotides	1971
Cyclic nucleotide phosphodiesterase: high activity in a mammalian photoreceptor. Science (New York, N.Y.), 1972, Feb-18, Volume: 175, Issue:4023 Topics: Animals; Brain; Butyrates; Caffeine; Cattle; Centrifugation, Density Gradient; Chickens; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Hydrolysis; Kinetics; Papaverine; Phosphoric Monoester Hydrolases; Photoreceptor Cells; Rats; Retina; Theophylline; Uracil Nucleotides	1972
Cyclic 3',5'-nucleotide phosphodiesterase properties of the enzyme of human blood platelets. Biochimica et biophysica acta, 1971, Sep-22, Volume: 242, Issue:3 Topics: Adenosine Triphosphate; Blood Platelets; Caffeine; Carbon Isotopes; Chlorides; Cobalt; Cyclic AMP; Cyclic GMP; Drug Stability; Edetic Acid; Erythrocytes; Humans; Hydrogen-Ion Concentration; Kinetics; Leukocytes; Magnesium; Manganese; Phosphoric Monoester Hydrolases; Ribonucleosides; Ribonucleotides; Subcellular Fractions; Temperature	1971
Urinary excretion of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate. The New England journal of medicine, 1972, Jun-29, Volume: 286, Issue:26 Topics: Adult; Caffeine; Calcitonin; Calcium; Carcinoma, Bronchogenic; Circadian Rhythm; Cyclic AMP; Cyclic GMP; Diagnosis, Differential; Humans; Hypercalcemia; Hyperparathyroidism; Hypoparathyroidism; Lung Neoplasms; Middle Aged; Osteitis Deformans; Parathyroid Glands; Parathyroid Neoplasms; Physical Exertion; Sarcoidosis	1972
1-Ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo-(3,4-b)-pyridine-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009)--a potent new inhibitor of cyclic 3',5'-nucleotide phosphodiesterases. Biochemical pharmacology, 1972, Sep-15, Volume: 21, Issue:18 Topics: Adrenal Glands; Ammonium Sulfate; Animals; Brain; Caffeine; Carboxylic Acids; Cats; Cattle; Cyclic AMP; Cyclic GMP; Esters; Hydrazines; Hydrolysis; In Vitro Techniques; Kinetics; Male; Myocardium; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazoles; Pyridines; Rats; Theophylline	1972
Characteristics of cyclic 3',5'-nucleotide phosphodiesterase from the brain of the Madagascar cockroach (Gromphadorhina portentosa). Comparative biochemistry and physiology. B, Comparative biochemistry, 1974, Jan-15, Volume: 47, Issue:1 Topics: Adenosine Triphosphate; Animals; Brain; Caffeine; Cations, Divalent; Citrates; Cockroaches; Colorimetry; Cyclic AMP; Cyclic GMP; Diphosphates; Drug Stability; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Magnesium; Organ Specificity; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridines; Reserpine; Temperature; Theophylline; Time Factors; Tritium; Xanthines	1974
Modulation by cyclic AMP in vitro of liver plasma membrane (Na+--K+)-ATPase and protein kinases. Biochimica et biophysica acta, 1974, Apr-22, Volume: 343, Issue:2 Topics: Adenosine Triphosphatases; Animals; Bucladesine; Butyrates; Caffeine; Cell Membrane; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Cytosine Nucleotides; Cytosol; Epinephrine; Kinetics; Liver; Magnesium; Male; Nucleotides, Cyclic; Potassium; Propranolol; Protein Kinases; Sodium; Theophylline	1974
Cyclic nucleotide phosphodiesterase of Chlamydomonas reinhardtii. Biochimica et biophysica acta, 1974, Apr-25, Volume: 341, Issue:2 Topics: Aminophylline; Bucladesine; Caffeine; Cations, Divalent; Chlamydomonas; Chromatography, Thin Layer; Cyclic AMP; Cyclic GMP; Diphosphates; Drug Stability; Edetic Acid; Enzyme Activation; Hydrogen-Ion Concentration; Inosine Nucleotides; Kinetics; Nucleotides, Cyclic; Phosphates; Phosphoric Diester Hydrolases; Sulfhydryl Reagents; Temperature; Theophylline; Thymine Nucleotides; Time Factors; Tritium; Uracil Nucleotides	1974
Inhibition of 2-deoxy-D-glucose transport by theophylline, caffeine and papaverine in alveolar macrophages. Biochemical pharmacology, 1974, Jun-15, Volume: 23, Issue:12 Topics: Animals; Biological Transport; Bucladesine; Caffeine; Carbon Radioisotopes; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Kinetics; Macrophages; Papaverine; Prostaglandins; Pulmonary Alveoli; Sucrose; Theophylline; Tritium	1974
Cyclic 3':5'-nucleotide phosphodiesterase. Purification, characterization, and active form of the protein activator from bovine brain. The Journal of biological chemistry, 1974, Aug-10, Volume: 249, Issue:15 Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Brain; Caffeine; Calcium; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclic AMP; Cyclic GMP; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Guanidines; Isoelectric Focusing; Molecular Weight; Nerve Tissue Proteins; Phosphoric Diester Hydrolases; Protein Binding; Protein Conformation; Spectrophotometry; Sulfhydryl Compounds; Ultracentrifugation	1974
Rod outer segment phosphodiesterase: factors affecting the hydrolysis of cyclic-AMP and cyclic-GMP. Experimental eye research, 1974, Volume: 18, Issue:6 Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Cattle; Cyclic AMP; Cyclic GMP; Dark Adaptation; Enzyme Activation; Freezing; Hot Temperature; Hydrolysis; In Vitro Techniques; Light; Magnesium; Manganese; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Photoreceptor Cells; Surface-Active Agents; Theophylline; Ultrasonics	1974
The aggregation of rabbit polymorphonuclear leucocytes: effects of antimitotic agents, cyclic nucleotides and methyl xanthines. Journal of cell science, 1974, Volume: 16, Issue:1 Topics: Adenine; Adenosine; Animals; Bucladesine; Caffeine; Cell Aggregation; Colchicine; Cyclic AMP; Cyclic GMP; Depression, Chemical; In Vitro Techniques; Leukocytes; Nucleotides, Cyclic; Rabbits; Stimulation, Chemical; Theobromine; Theophylline; Vinblastine; Xanthines	1974
Cyclic nucleotide phosphodiesterase in silkworm: purification and properties. Biochimica et biophysica acta, 1974, Nov-25, Volume: 370, Issue:1 Topics: Animals; Bombyx; Caffeine; Cations, Divalent; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Edetic Acid; Electrophoresis, Disc; Fluorides; Hydrogen-Ion Concentration; Hydroxyapatites; Imidazoles; Kinetics; Larva; Molecular Weight; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Temperature; Theophylline	1974
In vitro response of goldfish (Carassius auratus L.) dermal melanophores to cyclic 3',5'-nucleotides, nucleoside 5'-phosphates and methylxanthines. Journal of cellular physiology, 1974, Volume: 84, Issue:2 Topics: Adenosine Monophosphate; Animals; Binding, Competitive; Bucladesine; Caffeine; Chromatophores; Cyclic AMP; Cyclic GMP; Cyprinidae; Cytosine Nucleotides; Goldfish; Guanine Nucleotides; Melanophores; Nucleotides; Nucleotides, Cyclic; Skin; Theophylline; Thymine Nucleotides; Time Factors; Uracil Nucleotides	1974
The effects of caffeine on sodium transport, membrane potential, mechanical tension and ultrastructure in barnacle muscle fibres. The Journal of physiology, 1974, Volume: 242, Issue:1 Topics: Acetates; Animals; Biological Transport, Active; Caffeine; Calcium; Calcium Chloride; Chelating Agents; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Glycols; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Microscopy, Electron; Muscle Contraction; Myofibrils; Ouabain; Phenytoin; Phosphoric Diester Hydrolases; Procaine; Sodium; Stimulation, Chemical; Thoracica	1974
Cyclic nucleotide responses and radiation-induced mitotic delay in Physarum polycephalum. Radiation research, 1984, Volume: 97, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Caffeine; Cobalt Radioisotopes; Cyclic AMP; Cyclic GMP; Gamma Rays; Mitosis; Phosphodiesterase Inhibitors; Physarum; Theophylline; Time Factors	1984
Circadian variations in the effects of cyclic nucleotides on the thermoregulatory behaviour of a teleost fish. Neuropharmacology, 1981, Volume: 20, Issue:3 Topics: Animals; Body Temperature Regulation; Caffeine; Circadian Rhythm; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Fishes; Nucleotides, Cyclic	1981
Dissimilar effects on body temperature in the cat produced by guanosine 3',5'-monophosphate, acetylcholine and bacterial endotoxin. British journal of pharmacology, 1981, Volume: 74, Issue:2 Topics: Acetylcholine; Animals; Body Temperature; Caffeine; Cats; Cyclic GMP; Dibutyryl Cyclic GMP; Endotoxins; Female; Physostigmine	1981
The effects of calcium on protein turnover in skeletal muscles of the rat. The Biochemical journal, 1982, Apr-15, Volume: 204, Issue:1 Topics: Animals; Caffeine; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Dibucaine; In Vitro Techniques; Insulin; Male; Muscle Proteins; Muscles; Procaine; Rats; Thymol	1982
Caffeine blocks activation of cyclic AMP synthesis in Dictyostelium discoideum. Developmental biology, 1984, Volume: 101, Issue:1 Topics: Adenylyl Cyclases; Caffeine; Calcimycin; Cell Survival; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation	1984
The participation of elevated levels of cyclic GMP in the recovery from radiation-induced mitotic delay. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1984, Volume: 45, Issue:1 Topics: Caffeine; Cobalt Radioisotopes; Cyclic AMP; Cyclic GMP; Gamma Rays; Mitosis; Physarum; Time Factors	1984
Effects of caffeine, cyclic 3', 5' adenosine monophosphate and cyclic 3', 5' guanosine monophosphate in the development of the mycelial form of Sporothrix schenckii. Mycopathologia, 1984, Apr-30, Volume: 86, Issue:1 Topics: Bucladesine; Caffeine; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Humans; Kinetics; Spores, Fungal; Sporothrix	1984
Endothelium-dependent and -independent vasodilation of isolated rat aorta induced by caffeine. The American journal of physiology, 1995, Volume: 269, Issue:5 Pt 2 Topics: Animals; Aorta; Caffeine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Intracellular Membranes; Male; Nitroprusside; Rats; Rats, Wistar; Ryanodine; Vasodilation	1995
Methylxanthines and calcium-mobilizing agents inhibit the expression of cytokine-inducible nitric oxide synthase and vascular cell adhesion molecule-1 in murine microvascular endothelial cells. Experimental cell research, 1994, Volume: 212, Issue:2 Topics: Amino Acid Oxidoreductases; Animals; Atropine; Caffeine; Calcium; Carbachol; Cell Adhesion Molecules; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Gene Expression; Hydrogen-Ion Concentration; Interferon-gamma; Ionomycin; Mice; Nitric Oxide Synthase; Rats; Recombinant Proteins; RNA, Messenger; Signal Transduction; Terpenes; Thapsigargin; Theophylline; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Xanthines	1994
IBMX induces calcium release from intracellular stores in rat sensory neurones. Cell calcium, 1995, Volume: 17, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Biological Transport; Bucladesine; Caffeine; Calcium; Cell Compartmentation; Colforsin; Cyclic GMP; Dibutyryl Cyclic GMP; Endoplasmic Reticulum; Ganglia, Spinal; Neurons, Afferent; Rats; Theophylline	1995
[3H]9-Methyl-7-bromoeudistomin D, a caffeine-like powerful Ca2+ releaser, binds to caffeine-binding sites distinct from the ryanodine receptors in brain microsomes. FEBS letters, 1995, Oct-16, Volume: 373, Issue:3 Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Brain; Caffeine; Calcium; Calcium Channels; Carbolines; Cholic Acids; Cyclic GMP; Detergents; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Kinetics; Microsomes; Muscle Proteins; Procaine; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel	1995
Ca(2+)-channel blockade in rat thoracic aorta by crychine isolated from Cryptocarya chinensis Hemsl. The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:8 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds; Caffeine; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Dioxoles; Drug Interactions; Female; Male; Muscle Contraction; Nifedipine; Norepinephrine; Plant Extracts; Plants, Medicinal; Potassium; Rats; Rats, Wistar	1993
Role of nitric oxide on vasorelaxation in human umbilical artery. American journal of obstetrics and gynecology, 1995, Volume: 172, Issue:5 Topics: Caffeine; Calcimycin; Calcium; Cyclic GMP; Female; Histamine; Humans; In Vitro Techniques; Nitric Oxide; Nitroglycerin; Pregnancy; Umbilical Arteries; Vasodilation	1995
Relaxation of rat thoracic aorta induced by pyridine. European journal of pharmacology, 1995, Mar-16, Volume: 292, Issue:3-4 Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Pyridines; Rats; Rats, Wistar	1995
Immature maxi-K channels exhibit heterogeneous properties in the embryonic rat telencephalon. Developmental neuroscience, 1994, Volume: 16, Issue:1-2 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arachidonic Acid; Caffeine; Calcimycin; Cyclic GMP; Electric Conductivity; Embryo, Mammalian; Embryonic and Fetal Development; Female; Gestational Age; In Vitro Techniques; Ion Channel Gating; Kinetics; Linoleic Acid; Linoleic Acids; Membrane Potentials; Myristic Acid; Myristic Acids; Neurons; Patch-Clamp Techniques; Potassium Channels; Pregnancy; Rats; Rats, Sprague-Dawley; Telencephalon; Time Factors	1994
Vasorelaxing effect in rat thoracic aorta caused by laurotetanine isolated from Litsea cubeba Persoon. The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:5 Topics: Animals; Aorta, Thoracic; Aporphines; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; Drugs, Chinese Herbal; Female; In Vitro Techniques; Male; Molecular Structure; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Rats; Rats, Wistar; Vasodilator Agents	1994
Relaxation of rat thoracic aorta induced by 2,2',2''-tripyridine. European journal of pharmacology, 1994, Jan-03, Volume: 270, Issue:1 Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Male; Norepinephrine; Potassium; Pyridines; Rats; Rats, Wistar; Vasodilation	1994
Functional roles of cyclic guanosine 3',5'-monophosphate analogue in cerebral vasodilation. General pharmacology, 1993, Volume: 24, Issue:3 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Basilar Artery; Caffeine; Calcimycin; Calcium; Calcium Chloride; Cerebrovascular Circulation; Cyclic GMP; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Potassium; Vasoconstrictor Agents; Vasodilation	1993
The type 2 ryanodine receptor of neurosecretory PC12 cells is activated by cyclic ADP-ribose. Role of the nitric oxide/cGMP pathway. The Journal of biological chemistry, 1996, Jul-26, Volume: 271, Issue:30 Topics: Adenosine Diphosphate Ribose; Alkaloids; Animals; Biomarkers; Caffeine; Calcium; Calcium Channels; Carbazoles; Cyclic ADP-Ribose; Cyclic GMP; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Indoles; Ionomycin; Muscle Proteins; Neurosecretory Systems; Nitric Oxide; Nitroprusside; PC12 Cells; Penicillamine; Rats; Ryanodine Receptor Calcium Release Channel; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Terpenes; Thapsigargin	1996
Activation of voltage-independent Ca2+ entry by noradrenaline involves cGMP in vascular myocytes. Cell calcium, 1995, Volume: 18, Issue:6 Topics: Aminoquinolines; Animals; Antibiotics, Antineoplastic; Anticoagulants; Antifungal Agents; Biological Transport; Caffeine; Calcium; Calcium Channel Agonists; Cell Membrane; Cyclic GMP; Dibutyryl Cyclic GMP; Doxorubicin; Econazole; Enzyme Inhibitors; Ethers, Cyclic; Genistein; Heparin; Ion Channel Gating; Isoflavones; Membrane Potentials; Muscle, Smooth, Vascular; Norepinephrine; Okadaic Acid; Phosphodiesterase Inhibitors; Portal Vein; Rats; Rats, Wistar; Sodium; Sympathomimetics; Terpenes; Thapsigargin	1995
Simultaneous presence of cAMP and cGMP exert a co-ordinated inhibitory effect on the agonist-evoked Ca2+ signal in pancreatic acinar cells. Pflugers Archiv : European journal of physiology, 1996, Volume: 432, Issue:5 Topics: Acetylcholine; Animals; Caffeine; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Mice; Pancreas; Papaverine; Phosphoric Diester Hydrolases; Signal Transduction; Theophylline	1996
Role of cyclic nucleotides in contraction induced by oxytocin in the testicular capsule of the rat in vitro. Pharmacology, 1996, Volume: 53, Issue:5 Topics: Animals; Arginine; Caffeine; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Male; omega-N-Methylarginine; Oxytocin; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Testis; Theophylline	1996
Nitric oxide inhibits calcium release from sarcoplasmic reticulum of porcine tracheal smooth muscle cells. The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 1 Topics: Acetylcholine; Animals; Caffeine; Calcium; Cyclic GMP; Intracellular Membranes; Muscle, Smooth; Nitric Oxide; Osmolar Concentration; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sarcoplasmic Reticulum; Swine; Trachea	1997
Nitric oxide induces transient Ca2+ changes in endothelial cells independent of cGMP. Journal of cellular physiology, 1997, Volume: 172, Issue:3 Topics: Adenosine Triphosphate; Caffeine; Calcium; Cell Line; Cyclic GMP; Dantrolene; Diltiazem; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Nitric Oxide; Nitroprusside; Penicillamine; Procaine; Ryanodine; S-Nitroso-N-Acetylpenicillamine; Thapsigargin	1997
Diadenosine polyphosphates directly relax porcine coronary arterial smooth muscle. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Caffeine; Calcium; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dinucleoside Phosphates; Histamine; In Vitro Techniques; Muscle, Smooth, Vascular; Potassium Channel Blockers; Swine; Vasodilation	1997
Cicletanine-induced decreases in cytosolic Ca2+ level and contraction in vascular smooth muscle. Japanese journal of pharmacology, 1998, Volume: 76, Issue:1 Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Caffeine; Calcium; Central Nervous System Stimulants; Cyclic GMP; Cytosol; Dinoprost; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Pyridines; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Vasodilation	1998
Cyclic GMP-dependent but G-kinase-independent inhibition of Ca2+-dependent Cl- currents by NO donors in cat tracheal smooth muscle. The Journal of physiology, 1998, Sep-15, Volume: 511 ( Pt 3) Topics: Animals; Anthracenes; Caffeine; Calcium; Carbachol; Cats; Chloride Channels; Chlorides; Cyclic GMP; Dibutyryl Cyclic GMP; Enzyme Inhibitors; Female; GTP-Binding Proteins; Male; Membrane Potentials; Methylene Blue; Muscarinic Agonists; Muscle, Smooth; Nitric Oxide Donors; Patch-Clamp Techniques; Penicillamine; Phosphodiesterase Inhibitors; Receptor, Muscarinic M3; Receptors, Muscarinic; Ryanodine; Thionucleotides; Trachea; Zinc	1998
Inhibition of skeletal muscle sarcoplasmic reticulum Ca2+-ATPase by nitric oxide. FEBS letters, 1998, Nov-27, Volume: 440, Issue:1-2 Topics: Aminoquinolines; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium-Transporting ATPases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dithiothreitol; Guanylate Cyclase; Heparin; Inositol 1,4,5-Trisphosphate; Nitric Oxide; Ouabain; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase; Thapsigargin; Thionucleotides	1998
Relaxing effects of cyclic GMP and cyclic AMP-enhancing agents on the long-lasting contraction to endothelin-1 in the porcine coronary artery. Scandinavian journal of clinical and laboratory investigation, 1998, Volume: 58, Issue:8 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Isradipine; Milrinone; Muscle, Smooth, Vascular; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrrolidinones; Rolipram; Swine; Vasoactive Intestinal Peptide; Vasoconstriction; Vasodilation; Verapamil; Vinca Alkaloids	1998
Possible novel mechanism for bitter taste mediated through cGMP. Journal of neurophysiology, 1999, Volume: 81, Issue:4 Topics: Aminoquinolines; Animals; Caffeine; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Glycine Agents; Methylene Blue; Mice; Nitro Compounds; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Quaternary Ammonium Compounds; Quinoxalines; Signal Transduction; Strychnine; Sulfhydryl Reagents; Taste; Theophylline	1999
Effect of coadministration of caffeine and either adenosine agonists or cyclic nucleotides on ketorolac analgesia. European journal of pharmacology, 1999, Jul-21, Volume: 377, Issue:2-3 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Administration, Topical; Analgesics, Non-Narcotic; Animals; Caffeine; Central Nervous System Stimulants; Cyclic GMP; Cyclohexylamines; Disease Models, Animal; Drug Synergism; Female; Ketorolac; Pain; Pain Measurement; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Time Factors	1999
Different signalling pathways mediate the opposite effects of endogenous versus exogenous nitric oxide on hydroperoxide toxicity in CHP100 neuroblastoma cells. Journal of neurochemistry, 1999, Volume: 73, Issue:4 Topics: Caffeine; Calcium; Cell Survival; Cyclic GMP; Guanylate Cyclase; Humans; Kinetics; Neuroblastoma; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; tert-Butylhydroperoxide; Tumor Cells, Cultured	1999
Nitrergic relaxation of the mouse gastric fundus is mediated by cyclic GMP-dependent and ryanodine-sensitive mechanisms. British journal of pharmacology, 2000, Volume: 129, Issue:7 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Caffeine; Calcium Channel Blockers; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Oxadiazoles; Quinoxalines; Ryanodine	2000
Activation of the human, intermediate-conductance, Ca2+-activated K+ channel by methylxanthines. Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Caffeine; Calcium; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Gene Expression; Humans; Magnesium; Membrane Potentials; Nitroprusside; Patch-Clamp Techniques; Potassium Channels; Recombinant Proteins; Theophylline; Transfection; Xanthines	2000
The effects of phosphodiesterase inhibition on cyclic GMP and cyclic AMP accumulation in the hippocampus of the rat. Brain research, 2001, Jan-12, Volume: 888, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Guanylate Cyclase; Hippocampus; Image Processing, Computer-Assisted; Immunohistochemistry; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Norepinephrine; Phosphodiesterase Inhibitors; Purinones; Radioimmunoassay; Rats; Signal Transduction	2001
Hypothesis for the initiation of vasomotion. Circulation research, 2001, Apr-27, Volume: 88, Issue:8 Topics: Animals; Biological Clocks; Caffeine; Calcium Signaling; Cyclic GMP; Fluorescent Dyes; In Vitro Techniques; Isometric Contraction; Male; Membrane Potentials; Mesenteric Arteries; Microelectrodes; Models, Cardiovascular; Muscle, Smooth, Vascular; Norepinephrine; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasomotor System	2001
Effect of SIN-1 in rat ventricular myocytes: interference with beta-adrenergic stimulation. Life sciences, 2002, Jun-07, Volume: 71, Issue:3 Topics: Animals; Caffeine; Calcium; Calcium Channels; Cyclic AMP; Cyclic GMP; Drug Interactions; Heart Ventricles; In Vitro Techniques; Molsidomine; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Vasodilator Agents	2002
The effect of phosphodiesterase inhibition on gallbladder motility in vitro. The Journal of surgical research, 2002, Jun-15, Volume: 105, Issue:2 Topics: Animals; Caffeine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Gallbladder; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Opossums; Osmolar Concentration; Phosphodiesterase Inhibitors; Sincalide	2002
Activation of glycogen phosphorylase with 5-aminoimidazole-4-carboxamide riboside (AICAR). Assessment of glycogen as a precursor of mannosyl residues in glycoconjugates. The Journal of biological chemistry, 2004, Mar-26, Volume: 279, Issue:13 Topics: Amides; Aminoimidazole Carboxamide; Binding Sites; Caffeine; Catalysis; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP; Cyclic GMP; Enzyme Activation; Fibroblasts; Glycogen; Glycogen Phosphorylase; Humans; Hypoglycemic Agents; Indoles; Lipid Metabolism; Mannose; Metformin; Oligosaccharides; Phosphorylation; Protein Binding; Ribonucleotides; Skin; Time Factors	2004
Effects of procaine on a central neuron of the snail, Achatina fulica Ferussac. Life sciences, 2005, Feb-18, Volume: 76, Issue:14 Topics: Adenylyl Cyclases; Adrenergic Antagonists; Anesthetics, Local; Animals; Caffeine; Calcium; Calcium Channels; Cholinergic Antagonists; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; Ganglia, Invertebrate; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phospholipases; Procaine; Protein Kinase C; Ruthenium Red; Ryanodine; Snails; Synaptic Transmission; Type C Phospholipases	2005
Inhibition of carbachol-evoked oscillatory currents by the NO donor sodium nitroprusside in guinea-pig ileal myocytes. Experimental physiology, 2005, Volume: 90, Issue:4 Topics: Animals; Caffeine; Carbachol; Chelating Agents; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Egtazic Acid; Guinea Pigs; Ileum; In Vitro Techniques; Membrane Potentials; Muscarinic Agonists; Muscle Contraction; Myocytes, Smooth Muscle; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Quinoxalines; Type C Phospholipases	2005
Modulation by brain natriuretic peptide of GABA receptors on rat retinal ON-type bipolar cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jan-11, Volume: 26, Issue:2 Topics: Animals; Atrial Natriuretic Factor; Caffeine; Calcium; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Calmodulin; Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guanylate Cyclase; Heparin; Imidazoles; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Male; Membrane Potentials; Natriuretic Peptide, Brain; Oxazoles; Patch-Clamp Techniques; Peptide Fragments; Peptides, Cyclic; Polysaccharides; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Receptors, Cytoplasmic and Nuclear; Receptors, GABA; Receptors, GABA-A; Retinal Bipolar Cells; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin	2006
Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility. Circulation research, 2007, Feb-16, Volume: 100, Issue:3 Topics: Animals; Arginine; Caffeine; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Size; Cells, Cultured; Citrulline; Cyclic GMP; Doxycycline; Enzyme Induction; Ion Channel Gating; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide Synthase Type I; Ornithine; Protein Interaction Mapping; Recombinant Fusion Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stroke Volume; Ultrasonography; Ventricular Dysfunction, Left	2007
Hydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl. Cardiovascular research, 2010, Dec-01, Volume: 88, Issue:3 Topics: Animals; Caffeine; Calcium; Cyclic AMP; Cyclic GMP; Diethylamines; Hydrogen Sulfide; Models, Animal; Myocardium; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Rats; Rats, Sprague-Dawley	2010
cGMP reduces the sarcoplasmic reticulum Ca2+ loading in airway smooth muscle cells: a putative mechanism in the regulation of Ca2+ by cGMP. Journal of muscle research and cell motility, 2012, Volume: 32, Issue:6 Topics: Animals; Caffeine; Calcium; Cattle; Cyclic GMP; Dose-Response Relationship, Drug; Myocytes, Smooth Muscle; Sarcoplasmic Reticulum; Trachea	2012
Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells. Neuropharmacology, 2012, Volume: 63, Issue:8 Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antioxidants; Caffeine; Cells, Cultured; Central Nervous System Stimulants; Cyclic AMP; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; In Vitro Techniques; Melatonin; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Diseases; Neurons; Oxygen Consumption; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Reactive Oxygen Species; Signal Transduction; Transfection	2012
Modulation of high affinity ATP-dependent cyclic nucleotide transporters by specific and non-specific cyclic nucleotide phosphodiesterase inhibitors. European journal of pharmacology, 2014, Dec-15, Volume: 745 Topics: ATP-Binding Cassette Transporters; Caffeine; Carbolines; Cyclic AMP; Cyclic GMP; Dipyridamole; Humans; Imidazoles; Kinetics; Multidrug Resistance-Associated Proteins; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purinones; Sulfones; Tadalafil; Theophylline; Triazines; Vardenafil Dihydrochloride	2014