caffeine and chlorocresol

caffeine has been researched along with chlorocresol in 47 studies

Research

Studies (47)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.13)	18.7374
1990's	11 (23.40)	18.2507
2000's	31 (65.96)	29.6817
2010's	3 (6.38)	24.3611
2020's	1 (2.13)	2.80

Authors

Authors	Studies
Scutari, E; Tegazzin, V; Treves, S; Zorzato, F	1
Herrmann-Frank, A; Lehmann-Horn, F; Richter, M	1
Li, G; Pralong, WF; Wollheim, CB	1
Bittner, RE; Fricker, R; Gilly, H; Kress, HG; Musat, I; Steinbereithner, K	1
Adnet, PJ; Ben-Abraham, R; Haudcoeur, G; Krivosic-Horber, RM; Perel, A	1
Bendixen, D; Fagerlund, T; Gardi, T; Glahn, K; Ording, H	1
Andrade, FH; Islam, MS; Westerblad, H	1
Du, GG; MacLennan, DH	1
Allen, DG; Kabbara, AA	1
Choisy, S; Huchet-Cadiou, C; Leoty, C	2
Bao, JX; Copenhagen, DR; Krizaj, D; Schmitz, Y; Witkovsky, P	1
Baur, CP; Bellon, L; Felleiter, P; Fiege, M; Fricker, R; Georgieff, M; Glahn, K; Heffron, JJ; Herrmann-Frank, A; Jurkat-Rott, K; Klingler, W; Lehane, M; Lehmann-Horn, F; Ording, H; Tegazzin, V; Wappler, F	1
Allen, PD; Chen, SR; Fessenden, JD; Moore, RA; Pessah, IN; Wang, Y	1
Choisy, S; Divet, A; Huchet-Cadiou, C; Léoty, C	1
Moccagatta, L; Pouliquin, R; Treves, S; Zorzato, F	1
Cohen, J; Hentschel, J; Klauke, N; Mohamed, I; Plattner, H	1
Koenig, F; Neuhaus, J; Olthoff, D; Rueffert, H; Wehner, M	1
Fuller, GA; Ishida, K; Klomkleaw, W; Kurono, C; Nakajima, R; Oba, T; Takaishi, T; Yamaguchi, M	1
Allen, PD; López, JR	1
Bina, S; Brandom, BW; Daly, JW; Gallagher, KL; Holman, SJ; Hosoi, E; Muldoon, S; Pudimat, PA; Sei, Y; Venzon, DJ; Wyre, HW	1
Freymond, D; Guignet, R; Lhote, P; Passaquin, AC; Rüegg, UT	1
Allen, PD; Pessah, IN; Ta, TA; Yang, T	1
Allen, PD; Fessenden, JD; Goth, S; Perez, CF; Pessah, IN	1
Graves, TK; Hinkle, PM	1
Anetseder, M; Baur, CP; Censier, K; Doetsch, S; Felleiter, P; Fiege, M; Fricker, R; Halsall, PJ; Hartung, E; Heffron, JJ; Heytens, L; Hopkins, PM; Klingler, W; Lehmann-Horn, F; Nivoche, Y; Schulte am Esch, J; Tegazzin, V; Tzanova, I; Urwyler, A; Wappler, F; Weisshorn, R	1
George, CH; Higgs, GV; Lai, FA	1
BIGGS, DF	1
Koenig, F; Olthoff, D; Rueffert, H; Wehner, M	2
Kress, HG; Ludwig-Papst, C; Weigl, LG	1
Allen, PD; Feng, W; Fessenden, JD; Pessah, IN	1
Allen, PD; Linares, N; López, JR; Pessah, IN	1
Ducreux, S; Ferreiro, A; Jungbluth, H; Monnier, N; Müller, CR; Muntoni, F; Treves, S; Zorzato, F	1
Bina, S; Bünger, R; Cowan, G; Karaian, J; Mongan, P; Muldoon, S	1
Higure, Y; Nohmi, M; Shimazaki, Y	1
Butler, T; Klein, MG; McKinney, LC; Mullen, SP	1
Allard, B; Couchoux, H; Jacquemond, V; Pouvreau, S	1
Fogarty, KE; Lifshitz, LM; Singer, JJ; Tuft, RA; Zhang, YA; Zou, H	1
Liu, QH; Rathore, R; Wang, QS; Wang, YX; Yadav, V; Zheng, YM	1
Kaufmann, A; Kraft, B; Michalek-Sauberer, A; Weigl, LG	1
Meur, G; Rosker, C; Taylor, CW; Taylor, EJ	1
Girard, T; Levano, S; Matter, A; Singer, M; Treves, S; Urwyler, A; Vukcevic, M	1
Hamada, H; Kawamoto, M; Kobayashi, M; Migita, T; Mukaida, K; Yuge, O	1
Johannsen, S; Mögele, S; Müller, CR; Roewer, N; Schneiderbanger, D; Schuster, F; Treves, S	1
Hamada, H; Kanzaki, R; Kawamoto, M; Kondo, T; Miyoshi, H; Mukaida, K; Nishino, I; Otsuki, S; Yasuda, T	1
Almássy, J; Bárdi, M; Diszházi, G; Jóna, I; Kovács, T; Lukács, B; Magyar, ZÉ; Márton, I; Nánási, P; Novák, S; Péli-Szabó, J; Sárközi, S; Skaliczki, M	1

Trials

2 trial(s) available for caffeine and chlorocresol

Article	Year
A multicenter study of 4-chloro-m-cresol for diagnosing malignant hyperthermia susceptibility. Anesthesia and analgesia, 2000, Volume: 90, Issue:1 Topics: Caffeine; Central Nervous System Stimulants; Cresols; Europe; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Regression Analysis; Risk Assessment	2000
Multicentre evaluation of in vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility. European journal of anaesthesiology, 2003, Volume: 20, Issue:7 Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Sensitivity and Specificity	2003

Article

Year

A multicenter study of 4-chloro-m-cresol for diagnosing malignant hyperthermia susceptibility.

Anesthesia and analgesia, 2000, Volume: 90, Issue:1

Topics: Caffeine; Central Nervous System Stimulants; Cresols; Europe; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Regression Analysis; Risk Assessment

2000

Multicentre evaluation of in vitro contracture testing with bolus administration of 4-chloro-m-cresol for diagnosis of malignant hyperthermia susceptibility.

European journal of anaesthesiology, 2003, Volume: 20, Issue:7

Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Sensitivity and Specificity

2003

Other Studies

45 other study(ies) available for caffeine and chlorocresol

Article	Year
Chlorocresol, an additive to commercial succinylcholine, induces contracture of human malignant hyperthermia-susceptible muscles via activation of the ryanodine receptor Ca2+ channel. Anesthesiology, 1996, Volume: 84, Issue:6 Topics: Animals; Caffeine; Calcium; Calcium Channels; Cresols; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscle Proteins; Neuromuscular Depolarizing Agents; Rabbits; Ryanodine Receptor Calcium Release Channel; Succinylcholine	1996
4-Chloro-m-cresol: a specific tool to distinguish between malignant hyperthermia-susceptible and normal muscle. Biochemical pharmacology, 1996, Jul-12, Volume: 52, Issue:1 Topics: Animals; Caffeine; Calcium; Cresols; Malignant Hyperthermia; Muscle, Skeletal; Protein Binding; Ryanodine; Swine; Tritium	1996
Oscillations of cytosolic free calcium in bombesin-stimulated HIT-T15 cells. Cell calcium, 1996, Volume: 19, Issue:6 Topics: Animals; Biological Clocks; Bombesin; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Central Nervous System Stimulants; Chelating Agents; Circadian Rhythm; Cresols; Cricetinae; Cytosol; Diazoxide; Egtazic Acid; Fura-2; Glucose; Hydroquinones; Membrane Potentials; Ryanodine; Verapamil	1996
Classification of malignant hyperthermia-equivocal patients by 4-chloro-M-cresol. Anesthesia and analgesia, 1997, Volume: 85, Issue:1 Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Caffeine; Cresols; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle, Skeletal; Sensitivity and Specificity	1997
[Effect of chlorocresol vs caffeine on muscle contracture in malignant hyperthermia susceptible patients]. Harefuah, 1997, Jun-15, Volume: 132, Issue:12 Topics: Adolescent; Adult; Caffeine; Cresols; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Phenotype	1997
4-Chloro-m-cresol test--a possible supplementary test for diagnosis of malignant hyperthermia susceptibility. Acta anaesthesiologica Scandinavica, 1997, Volume: 41, Issue:8 Topics: Biopsy; Caffeine; Cresols; Disease Susceptibility; Dose-Response Relationship, Drug; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Ryanodine	1997
Effects of ryanodine receptor agonist 4-chloro-m-cresol on myoplasmic free Ca2+ concentration and force of contraction in mouse skeletal muscle. Cell calcium, 1998, Volume: 24, Issue:2 Topics: Animals; Caffeine; Calcium; Chlorophenols; Cresols; Dantrolene; Electric Stimulation; Male; Membrane Potentials; Mice; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum	1998
Functional consequences of mutations of conserved, polar amino acids in transmembrane sequences of the Ca2+ release channel (ryanodine receptor) of rabbit skeletal muscle sarcoplasmic reticulum. The Journal of biological chemistry, 1998, Nov-27, Volume: 273, Issue:48 Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Caffeine; Calcium; Cell Line; Conserved Sequence; Cresols; Humans; Kinetics; Macromolecular Substances; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Point Mutation; Rabbits; Recombinant Proteins; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sequence Alignment; Sequence Homology, Amino Acid; Transfection; Valine	1998
Measurement of sarcoplasmic reticulum Ca2+ content in intact amphibian skeletal muscle fibres with 4-chloro-m-cresol. Cell calcium, 1999, Volume: 25, Issue:3 Topics: Animals; Bufo marinus; Caffeine; Calcium; Central Nervous System Stimulants; Cresols; Dose-Response Relationship, Drug; Electrophysiology; Indoles; Muscle, Skeletal; Sarcoplasmic Reticulum	1999
Sarcoplasmic reticulum Ca(2+) release by 4-chloro-m-cresol (4-CmC) in intact and chemically skinned ferret cardiac ventricular fibers. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2 Topics: Animals; Caffeine; Calcium; Contractile Proteins; Cresols; Ferrets; Heart Ventricles; In Vitro Techniques; Kinetics; Male; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Octoxynol; Ryanodine Receptor Calcium Release Channel; Saponins; Sarcoplasmic Reticulum	1999
Caffeine-sensitive calcium stores regulate synaptic transmission from retinal rod photoreceptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Sep-01, Volume: 19, Issue:17 Topics: Ambystoma; Animals; Barium; Caffeine; Calcium; Calcium Channels; Chelating Agents; Cresols; Egtazic Acid; Electrophysiology; In Vitro Techniques; Kinetics; Models, Neurological; Presynaptic Terminals; Retinal Rod Photoreceptor Cells; Ryanodine; Synaptic Transmission; Thymol; Xenopus laevis	1999
Differential effects of 4-chloro-m-cresol and caffeine on skinned fibers from rat fast and slow skeletal muscles. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3 Topics: Animals; Caffeine; Calcium; Contractile Proteins; Cresols; In Vitro Techniques; Male; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Octoxynol; Rats; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Surface-Active Agents	2000
Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line. Biophysical journal, 2000, Volume: 79, Issue:5 Topics: Animals; Biophysical Phenomena; Biophysics; Caffeine; Calcium Signaling; Cell Line; Cresols; Electrophysiology; Gene Expression; Herpesvirus 1, Human; Mice; Muscle Contraction; Muscle, Skeletal; Protein Isoforms; Recombinant Proteins; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Tacrolimus Binding Protein 1A; Transduction, Genetic	2000
Sarcoplasmic reticulum Ca(2+) content affects 4-CmC and caffeine contractures of rat skinned skeletal muscle fibers. The Japanese journal of physiology, 2001, Volume: 51, Issue:6 Topics: Animals; Caffeine; Calcium; Cresols; Dose-Response Relationship, Drug; Fungicides, Industrial; Male; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Weight-Bearing	2001
Functional properties of EGFP-tagged skeletal muscle calcium-release channel (ryanodine receptor) expressed in COS-7 cells: sensitivity to caffeine and 4-chloro-m-cresol. Cell calcium, 2002, Volume: 31, Issue:1 Topics: Animals; Caffeine; Calcium; Central Nervous System Stimulants; COS Cells; Cresols; Fluorescent Antibody Technique; Green Fluorescent Proteins; Luminescent Proteins; Recombinant Proteins; Ryanodine Receptor Calcium Release Channel; Tritium	2002
Functional and fluorochrome analysis of an exocytotic mutant yields evidence of store-operated Ca2+ influx in Paramecium. The Journal of membrane biology, 2002, May-01, Volume: 187, Issue:1 Topics: Animals; Caffeine; Calcium; Calcium Channels; Cell Line; Cresols; Dextrans; Exocytosis; Fluorescent Dyes; Mutation; Paramecium tetraurelia; Sensitivity and Specificity	2002
Increased sensitivity to 4-chloro-m-cresol and caffeine in primary myotubes from malignant hyperthermia susceptible individuals carrying the ryanodine receptor 1 Thr2206Met (C6617T) mutation. Clinical genetics, 2002, Volume: 62, Issue:2 Topics: Amino Acid Substitution; Caffeine; Calcium; Cresols; Female; Humans; Male; Malignant Hyperthermia; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Pedigree; Potassium Chloride; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum	2002
H2O2 activates ryanodine receptor but has little effect on recovery of releasable Ca2+ content after fatigue. Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 93, Issue:6 Topics: Animals; Caffeine; Calcium; Catalase; Cresols; Homeostasis; Hydrogen Peroxide; Membrane Potentials; Muscle Contraction; Muscle Fatigue; Oxidants; Oxidation-Reduction; Phosphodiesterase Inhibitors; Rana catesbeiana; Recovery of Function; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum	2002
"Noninvasive" testing for malignant hyperthermia susceptibility. Anesthesiology, 2002, Volume: 97, Issue:5 Topics: Caffeine; Calcium; Cresols; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Muscle Contraction	2002
Patients with malignant hyperthermia demonstrate an altered calcium control mechanism in B lymphocytes. Anesthesiology, 2002, Volume: 97, Issue:5 Topics: Adolescent; Adult; B-Lymphocytes; Caffeine; Calcium; Child; Cresols; Disease Susceptibility; Halothane; Humans; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Mutation; Ryanodine Receptor Calcium Release Channel	2002
Calcium homeostasis and glucose uptake of murine myotubes exposed to insulin, caffeine and 4-chloro-m-cresol. Acta physiologica Scandinavica, 2002, Volume: 176, Issue:4 Topics: Animals; Caffeine; Calcium; Cell Line; Cresols; Cytosol; Dose-Response Relationship, Drug; Glucose; Homeostasis; Insulin; L-Lactate Dehydrogenase; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Ryanodine Receptor Calcium Release Channel	2002
Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling. The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28 Topics: Animals; Caffeine; Calcium; Cell Membrane; Central Nervous System Stimulants; Collagen; Cresols; DNA, Complementary; Dose-Response Relationship, Drug; Drug Combinations; Herpesvirus 1, Human; Immunoblotting; Inhibitory Concentration 50; Laminin; Magnesium; Malignant Hyperthermia; Mice; Muscle Contraction; Muscle, Skeletal; Muscles; Mutation; Potassium Chloride; Protein Structure, Tertiary; Proteoglycans; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel	2003
Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol. The Journal of biological chemistry, 2003, Aug-01, Volume: 278, Issue:31 Topics: Animals; Caffeine; Calcium; Cresols; Gene Expression; Molecular Weight; Muscle Fibers, Skeletal; Mutagenesis, Site-Directed; Potassium Chloride; Protein Isoforms; Rabbits; Recombinant Fusion Proteins; Ryanodine; Ryanodine Receptor Calcium Release Channel; Structure-Activity Relationship; Transfection; Tritium	2003
Ca(2+)-induced Ca(2+) release in the pancreatic beta-cell: direct evidence of endoplasmic reticulum Ca(2+) release. Endocrinology, 2003, Volume: 144, Issue:8 Topics: Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cell Line; Cresols; Cytoplasm; Endoplasmic Reticulum; Glucose; Islets of Langerhans; Membrane Potentials; Potassium Chloride; Ryanodine; Ryanodine Receptor Calcium Release Channel; Type C Phospholipases	2003
Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes. Circulation research, 2003, Sep-19, Volume: 93, Issue:6 Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Caffeine; Calcium; Cell Line; Cresols; Humans; Isoproterenol; Mutation; Myocytes, Cardiac; Phenotype; Ryanodine Receptor Calcium Release Channel; Stress, Physiological; Tachycardia, Ventricular; Tacrolimus Binding Proteins	2003
EXPERIMENTS ON THE MECHANISM OF ACTION OF CHLOROCRESOL AND CAFFEINE. British journal of pharmacology and chemotherapy, 1965, Volume: 24 Topics: Acetylcholine; Animals; Anura; Caffeine; Calcium; Cholinesterase Inhibitors; Cresols; Cyanides; Edetic Acid; Fluorides; Fructose; Gallamine Triethiodide; Glucose; Hexosephosphates; Iodoacetates; Metabolism; Muscle Contraction; Pharmacology; Potassium Chloride; Procaine; Research; Sodium; Tubocurarine	1965
Calcium release from sarcoplasmic reticulum is facilitated in human myotubes derived from carriers of the ryanodine receptor type 1 mutations Ile2182Phe and Gly2375Ala. Genetic testing, 2003,Fall, Volume: 7, Issue:3 Topics: Adult; Aged; Caffeine; Calcium; Child; Child, Preschool; Cresols; Female; Genetic Predisposition to Disease; Halothane; Heterozygote; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Contraction; Muscle Fibers, Skeletal; Point Mutation; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum	2003
Functional characterization of malignant hyperthermia-associated RyR1 mutations in exon 44, using the human myotube model. Neuromuscular disorders : NMD, 2004, Volume: 14, Issue:7 Topics: Adolescent; Adult; Aged; Anesthetics; Biopsy; Caffeine; Calcium; Cells, Cultured; Central Nervous System Stimulants; Child; Child, Preschool; Cresols; Dose-Response Relationship, Drug; Exons; Family Health; Fungicides, Industrial; Fura-2; Halothane; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; Middle Aged; Molecular Biology; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Ryanodine Receptor Calcium Release Channel	2004
4-chloro-m-cresol cannot detect malignant hyperthermia equivocal cells in an alternative minimally invasive diagnostic test of malignant hyperthermia susceptibility. Anesthesia and analgesia, 2004, Volume: 99, Issue:1 Topics: Caffeine; Calcium; Calibration; Cells, Cultured; Central Nervous System Stimulants; Cresols; DNA Mutational Analysis; DNA, Complementary; Fluorescent Dyes; Fura-2; Humans; Malignant Hyperthermia; Microtubules; Muscle Contraction; Muscle, Smooth, Vascular; RNA, Messenger; Ryanodine Receptor Calcium Release Channel	2004
Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RyR1. The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51 Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Caffeine; Calcium; Cresols; DNA Mutational Analysis; DNA, Complementary; Dose-Response Relationship, Drug; Fungicides, Industrial; Immunoblotting; Mice; Molecular Sequence Data; Muscle, Skeletal; Muscles; Mutation; Phosphodiesterase Inhibitors; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sequence Homology, Amino Acid	2004
Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i. American journal of physiology. Cell physiology, 2005, Volume: 288, Issue:3 Topics: Animals; Animals, Newborn; Caffeine; Calcium; Central Nervous System Stimulants; Chelating Agents; Cresols; Egtazic Acid; Electrophysiology; Fungicides, Industrial; Malignant Hyperthermia; Membrane Potentials; Microelectrodes; Muscle, Skeletal; Swine	2005
Functional properties of ryanodine receptors carrying three amino acid substitutions identified in patients affected by multi-minicore disease and central core disease, expressed in immortalized lymphocytes. The Biochemical journal, 2006, Apr-15, Volume: 395, Issue:2 Topics: Amino Acid Substitution; Caffeine; Calcium Signaling; Case-Control Studies; Cells, Cultured; Cresols; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Herpesvirus 4, Human; Humans; Lymphocytes; Mutation; Myopathy, Central Core; Ryanodine Receptor Calcium Release Channel; Thapsigargin	2006
Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis. Anesthesiology, 2006, Volume: 104, Issue:1 Topics: Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Caffeine; Central Nervous System Stimulants; Creatine Kinase; Cresols; Dose-Response Relationship, Drug; Electrolytes; Glucose; Halothane; Ketamine; Lactic Acid; Malignant Hyperthermia; Microdialysis; Muscle, Skeletal; Propofol; Pyruvic Acid; Ryanodine Receptor Calcium Release Channel; Swine	2006
Can 4-chloro-m-cresol be substituted for caffeine as an activator of calcium oscillation in bullfrog sympathetic ganglion cells? Cell calcium, 2006, Volume: 39, Issue:5 Topics: Animals; Caffeine; Calcium Signaling; Cells, Cultured; Cresols; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Rana catesbeiana; Ryanodine	2006
Characterization of ryanodine receptor-mediated calcium release in human B cells: relevance to diagnostic testing for malignant hyperthermia. Anesthesiology, 2006, Volume: 104, Issue:6 Topics: Animals; B-Lymphocytes; Caffeine; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cresols; Dose-Response Relationship, Drug; Humans; Imidazoles; Malignant Hyperthermia; Oxazoles; Ryanodine; Ryanodine Receptor Calcium Release Channel; Swine	2006
Sarcoplasmic reticulum Ca2+ release and depletion fail to affect sarcolemmal ion channel activity in mouse skeletal muscle. The Journal of physiology, 2006, Aug-15, Volume: 575, Issue:Pt 1 Topics: Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cresols; Delayed Rectifier Potassium Channels; Enzyme Inhibitors; In Vitro Techniques; Indoles; Ion Channel Gating; Male; Membrane Potentials; Mice; Mice, Inbred mdx; Muscle, Skeletal; Patch-Clamp Techniques; Sarcolemma; Sarcoplasmic Reticulum	2006
Caffeine-activated large-conductance plasma membrane cation channels in cardiac myocytes: characteristics and significance. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cell Membrane; Cresols; Enzyme Inhibitors; Heart Atria; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Mice; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tetracaine; Thapsigargin	2007
Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells. Journal of vascular research, 2008, Volume: 45, Issue:6 Topics: Animals; Caffeine; Calcium Signaling; Cell Hypoxia; Cresols; Gene Expression Regulation; In Vitro Techniques; Kinetics; Male; Mesenteric Arteries; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Potassium; Pulmonary Artery; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ryanodine Receptor Calcium Release Channel	2008
Novel ryanodine receptor mutation that may cause malignant hyperthermia. Anesthesiology, 2008, Volume: 109, Issue:3 Topics: Amino Acid Substitution; Anesthetics, Inhalation; Austria; Caffeine; Calcium; Cells, Cultured; Central Nervous System Stimulants; Child; Cresols; Dose-Response Relationship, Drug; Female; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Patch-Clamp Techniques; Polymerase Chain Reaction; RNA, Messenger; Ryanodine Receptor Calcium Release Channel	2008
Functional ryanodine receptors in the plasma membrane of RINm5F pancreatic beta-cells. The Journal of biological chemistry, 2009, Feb-20, Volume: 284, Issue:8 Topics: Animals; Caffeine; Calcium; Calcium Channel Agonists; Cell Line, Tumor; Cell Membrane; Central Nervous System Stimulants; Cresols; Dose-Response Relationship, Drug; Fungicides, Industrial; Inositol 1,4,5-Trisphosphate Receptors; Insulin-Secreting Cells; Male; Rats; Rats, Wistar; Ryanodine; Ryanodine Receptor Calcium Release Channel	2009
Increasing the number of diagnostic mutations in malignant hyperthermia. Human mutation, 2009, Volume: 30, Issue:4 Topics: Caffeine; Calcium; Cell Line, Transformed; Cresols; DNA Mutational Analysis; Dose-Response Relationship, Drug; Family Health; Gene Frequency; Genetic Testing; Genotype; Humans; Lymphocytes; Malignant Hyperthermia; Mutation; Phenotype; Ryanodine Receptor Calcium Release Channel	2009
Analysis of human cultured myotubes responses mediated by ryanodine receptor 1. Anaesthesia and intensive care, 2011, Volume: 39, Issue:2 Topics: Adolescent; Adult; Aged; Caffeine; Calcium; Cells, Cultured; Child; Child, Preschool; Cresols; Dose-Response Relationship, Drug; Female; Genetic Predisposition to Disease; Halothane; Humans; Male; Malignant Hyperthermia; Middle Aged; Muscle Fibers, Skeletal; ROC Curve; Ryanodine Receptor Calcium Release Channel; Young Adult	2011
Functional characterization of the RYR1 mutation p.Arg4737Trp associated with susceptibility to malignant hyperthermia. Neuromuscular disorders : NMD, 2016, Volume: 26, Issue:1 Topics: Anesthetics; Arginine; B-Lymphocytes; Caffeine; Cell Line, Transformed; Cresols; Family Health; Female; Fungicides, Industrial; Genetic Predisposition to Disease; Germany; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Phosphodiesterase Inhibitors; Polymorphism, Single Nucleotide; Ryanodine Receptor Calcium Release Channel; Tryptophan	2016
Genetic and functional analysis of the RYR1 mutation p.Thr84Met revealed a susceptibility to malignant hyperthermia. Journal of anesthesia, 2018, Volume: 32, Issue:2 Topics: Animals; Caffeine; Calcium; Child; Cresols; Genetic Predisposition to Disease; HEK293 Cells; Humans; Male; Malignant Hyperthermia; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Rabbits; Ryanodine Receptor Calcium Release Channel	2018
4-chloro-orto-cresol activates ryanodine receptor more selectively and potently than 4-chloro-meta-cresol. Cell calcium, 2020, Volume: 88 Topics: Adenosine Triphosphatases; Animals; Caffeine; Calcium; Cresols; Hydrolysis; Ion Channel Gating; Ions; Microsomes; Muscle Contraction; Rabbits; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stereoisomerism	2020