caffeine has been researched along with camptothecin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Andersson, HC; Kihlman, BA | 1 |
| Shin, CG; Snapka, RM; Strayer, JM; Wani, MA | 1 |
| Evans, A; Johnson, RT; Ryan, AJ; Squires, S; Strutt, HL | 1 |
| Ardelt, B; Darzynkiewicz, RJ; Darzynkiewicz, Z; Gong, J; Kapuscinski, J; Traganos, F | 1 |
| Kaneko, S; Mizuno, K; Okada, M | 1 |
| Bernhard, EJ; Janss, AJ; Levow, C; McKenna, WG; Muschel, RJ; Phillips, PC; Sutton, L | 1 |
| Wang, Y; Zhou, XY | 1 |
| Enomoto, T; Kobayashi, T; Murofushi, H; Seki, M; Tada, S; Tsuyama, T | 1 |
| Bhonde, MR; Boland, CR; Hanski, C; Hanski, ML; Magrini, R; Notter, M; Scherübl, H; Zeitz, M | 1 |
| Block, WD; Lees-Miller, SP; Meek, K; Merkle, D | 1 |
| Arooz, T; Chow, JP; Ho, HT; Lau, A; Poon, RY; Siu, WY | 1 |
| Ferrara, L; Kmiec, EB | 1 |
| Chen, SY; Kussick, SJ; Roberson, RS; Vallieres, E; Wu, DY | 1 |
| Feng, YD; Gong, JP; Tan, HL; Tao, DD; Xiao, H; Xie, DX; Yu, CN | 1 |
| Blain, SW; Ye, W | 1 |
| Kim, KP; Lee, BK; Yoon, S | 1 |
22 other study(ies) available for caffeine and camptothecin
| Article | Year |
|---|---|
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Enhancement and reduction by methylated oxypurines of the frequencies of chromatid aberrations induced by camptothecin in root-tip cells of Vicia faba.
Topics: Caffeine; Camptothecin; Chromatids; Chromosome Aberrations; Dose-Response Relationship, Drug; Methylnitrosourea; Mutagenicity Tests; Mutagens; Plants; Purines; Theophylline; Uric Acid | 1992 |
Rapid evaluation of topoisomerase inhibitors: caffeine inhibition of topoisomerases in vivo.
Topics: Animals; Caffeine; Camptothecin; Etoposide; Haplorhini; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1990 |
Different fates of camptothecin-induced replication fork-associated double-strand DNA breaks in mammalian cells.
Topics: Animals; Caffeine; Camptothecin; Cell Line; CHO Cells; Chromosome Aberrations; Cricetinae; DNA; DNA Damage; DNA Replication; DNA, Neoplasm; Humans; Mitosis; Sensitivity and Specificity; Skin; Skin Physiological Phenomena; Urinary Bladder Neoplasms | 1994 |
Caffeine prevents apoptosis and cell cycle effects induced by camptothecin or topotecan in HL-60 cells.
Topics: Antineoplastic Agents; Apoptosis; Caffeine; Camptothecin; Cell Cycle; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Topotecan; Tumor Cells, Cultured | 1993 |
Adenosine A1 and A2 receptors modulate extracellular dopamine levels in rat striatum.
Topics: Adenosine; Animals; Antihypertensive Agents; Caffeine; Camptothecin; Dopamine; Enzyme Inhibitors; Extracellular Space; Irinotecan; Male; Microdialysis; Neostriatum; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theobromine; Vasodilator Agents | 1996 |
Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines.
Topics: Apoptosis; Brain Neoplasms; Caffeine; Camptothecin; Cisplatin; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; G2 Phase; Humans; Staurosporine; Tumor Cells, Cultured | 1998 |
Inhibition of DNA replication in camptothecin-treated cells is regulated by protein kinases.
Topics: Androstadienes; Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia Mutated Proteins; Caffeine; Camptothecin; Cell Cycle Proteins; DNA Damage; DNA Replication; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; HeLa Cells; Humans; Mutation; Nuclear Proteins; Phosphodiesterase Inhibitors; Protein Serine-Threonine Kinases; S Phase; Tumor Suppressor Proteins; Wortmannin | 2000 |
Focus-formation of replication protein A, activation of checkpoint system and DNA repair synthesis induced by DNA double-strand breaks in Xenopus egg extract.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Biotin; Caffeine; Camptothecin; Cell Cycle Proteins; Cell Extracts; Cell Nucleus; Cell-Free System; Deoxyuracil Nucleotides; DNA Damage; DNA Repair; DNA-Binding Proteins; Eukaryotic Cells; Female; Geminin; Genes, cdc; Male; Oocytes; Protein Serine-Threonine Kinases; Replication Protein A; Site-Specific DNA-Methyltransferase (Adenine-Specific); Spermatozoa; Tumor Suppressor Proteins; Xenopus laevis; Xenopus Proteins | 2002 |
Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Blotting, Western; Caffeine; Camptothecin; Carrier Proteins; CDC2 Protein Kinase; Cell Cycle; Colonic Neoplasms; Drug Resistance, Neoplasm; Flow Cytometry; Gene Deletion; Humans; Irinotecan; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine.
Topics: Animals; Caffeine; Camptothecin; Cell Extracts; Cell Line; Cricetinae; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Radiation-Sensitizing Agents; Replication Protein A | 2004 |
Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.
Topics: Antibiotics, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Caffeine; Camptothecin; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; G1 Phase; G2 Phase; Genes, cdc; Guanine Nucleotide Exchange Factors; Humans; Nuclear Proteins; Protein Serine-Threonine Kinases; S Phase; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Suppressor Proteins | 2004 |
Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombination.
Topics: Androstadienes; Antineoplastic Agents, Phytogenic; Base Sequence; Benzaldehydes; Caffeine; Camptothecin; Cell Line, Tumor; DNA Damage; DNA Repair; Green Fluorescent Proteins; Humans; Luminescent Proteins; Molecular Sequence Data; Oligonucleotides; Recombination, Genetic; Wortmannin | 2004 |
Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Caffeine; Camptothecin; Carboplatin; Carcinoma, Non-Small-Cell Lung; CDC2 Protein Kinase; Cell Division; Cell Line, Tumor; Cellular Senescence; G2 Phase; Humans; Lung Neoplasms; Neoadjuvant Therapy; Paclitaxel; Randomized Controlled Trials as Topic; Research Support as Topic; RNA, Small Interfering; Transcription, Genetic; Tumor Suppressor Protein p53 | 2005 |
[Effect of caffeine on camptothecin-induced apoptosis of Molt-4 cells].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caffeine; Camptothecin; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia, T-Cell; S Phase | 2005 |
Chk1 has an essential role in the survival of differentiated cortical neurons in the absence of DNA damage.
Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caffeine; Camptothecin; Cell Cycle Proteins; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebral Cortex; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Damage; DNA-Binding Proteins; Female; Genes, p53; Genomic Instability; Neurons; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Staurosporine; Tumor Suppressor Proteins | 2011 |
Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer.
Topics: Adenocarcinoma; Caffeine; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; DNA; Humans; Irinotecan | 2023 |