caffeine has been researched along with bupivacaine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 9 (42.86) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN | 1 |
| Camu, F | 1 |
| Fichter-Gagnepain, V; Louboutin, JP; Noireaud, J | 1 |
| Agustí, M; Carrero, EJ; Fábregas, N; Fernández, C; Valldeoriola, F | 1 |
| Fink, RH; Graf, BM; Kunst, G; Martin, E; Sinner, B; Zink, W | 1 |
| Fink, RH; Graf, BM; Martin, E; Missler, G; Sinner, B; Zink, W | 1 |
| Abengochea Cotaina, A; Gallego García, J; Jordá Sanz, L; León Carsí, I | 1 |
| Jasti, B; Kulkarni, U; Li, X; Mahalingam, R; Pather, SI | 1 |
| Aly, A; Farouk, S | 1 |
| Bollwein, G; Graf, BM; Gruber, M; Hofmann, P; Metterlein, T; Plank, C; Zink, W | 1 |
| Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE | 1 |
1 trial(s) available for caffeine and bupivacaine
| Article | Year |
|---|---|
A comparison of intra-articular magnesium and/or morphine with bupivacaine for postoperative analgesia after arthroscopic knee surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anesthetics, Local; Arthroscopy; Bupivacaine; Caffeine; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Injections, Intra-Articular; Magnesium Sulfate; Male; Morphine; Pain Measurement; Pain, Postoperative | 2009 |
20 other study(ies) available for caffeine and bupivacaine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain | 2016 |
Effects of local anesthetics on glucose-stimulated insulin secretion from rat pancreas in vitro.
Topics: Anesthetics, Local; Animals; Antigens; Bupivacaine; Caffeine; Calcium; Cyclic AMP; Dibucaine; Glucose; In Vitro Techniques; Insulin; Insulin Antibodies; Insulin Secretion; Lidocaine; Mepivacaine; Neutralization Tests; Pancreas; Potassium; Prilocaine; Procaine; Rats; Stimulation, Chemical; Tetracaine | 1973 |
External calcium dependence of extensor digitorum longus muscle contractility during bupivacaine-induced regeneration.
Topics: Animals; Bupivacaine; Caffeine; Calcium; Glycerol; Male; Muscle Contraction; Muscles; Rats; Rats, Wistar; Regeneration | 1996 |
Unilateral trigeminal and facial nerve palsies associated with epidural analgesia in labour.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bupivacaine; Caffeine; Central Nervous System Stimulants; Cranial Nerve Diseases; Facial Paralysis; Female; Fluid Therapy; Headache; Humans; Infant, Newborn; Intracranial Hypotension; Lysine; Methadone; Narcotics; Obstetric Labor, Premature; Opioid-Related Disorders; Palliative Care; Paralysis; Pregnancy; Spinal Puncture; Syndrome; Trigeminal Nerve | 1998 |
Differential effects of bupivacaine on intracellular Ca2+ regulation: potential mechanisms of its myotoxicity.
Topics: Anesthetics, Local; Animals; Bupivacaine; Caffeine; Calcium; Contractile Proteins; In Vitro Techniques; Isometric Contraction; Mice; Mice, Inbred BALB C; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphodiesterase Inhibitors; Sarcoplasmic Reticulum | 2002 |
Differential effects of bupivacaine and ropivacaine enantiomers on intracellular Ca2+ regulation in murine skeletal muscle fibers.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Caffeine; Calcium; Calcium Signaling; Central Nervous System Stimulants; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Ropivacaine; Sarcoplasmic Reticulum; Stereoisomerism | 2005 |
[Blood patch in a patient with postdural puncture headache].
Topics: Accidents; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bed Rest; Betamethasone; Blood Patch, Epidural; Bupivacaine; Caffeine; Combined Modality Therapy; Dura Mater; Female; Humans; Injections; Myofascial Pain Syndromes; Post-Dural Puncture Headache; Pregnancy | 2006 |
Porcine buccal mucosa as an in vitro model: relative contribution of epithelium and connective tissue as permeability barriers.
Topics: Administration, Buccal; Animals; Antipyrine; Bupivacaine; Buspirone; Caffeine; Cell Membrane Permeability; Connective Tissue Cells; Diffusion; Diffusion Chambers, Culture; Epithelial Cells; Kinetics; Lipid Bilayers; Models, Biological; Mouth Mucosa; Swine; Technology, Pharmaceutical | 2009 |
Modification of Bupivacaine-Induced Myotoxicity with Dantrolene and Caffeine In Vitro.
Topics: Anesthetics, Local; Animals; Annexins; Bupivacaine; Caffeine; Central Nervous System Stimulants; Dantrolene; In Vitro Techniques; Mice; Mice, Inbred BALB C; Muscle Relaxants, Central; Muscular Diseases; Necrosis; Primary Cell Culture | 2016 |
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine | 2016 |