caffeine has been researched along with benzocaine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A | 1 |
| Cruccu, G; Ferracuti, S; Innocenti, P; Leardi, MG; Prandi, P | 1 |
| Di Gennaro, M; Vassalle, M | 1 |
| Bondani, A; Karler, R | 1 |
| Desai, SJ; Higuchi, WI; Simonelli, AP; Singh, P | 1 |
| Levine, J; Weber, JD | 1 |
| Desai, SJ; Higuchi, WI; Mir, NA | 1 |
| Bhattacharyya, ML; Vassalle, M | 1 |
| HIGUCHI, T; LACH, JL | 1 |
| HIGUCHI, T; LACHMAN, L | 1 |
| Scrivens, JH; Williams, JP | 1 |
| Kolavennu, A; Liu, S; Mobley, DL; Paluch, AS; Parameswaran, S | 1 |
| Augusti, R; De Carvalho, TC; Filgueiras, PR; França, HS; Merlo, BB; Ortiz, RS; Rodrigues, RR; Romão, W; Santos, H; Souza, LM; Tosato, F; Vaz, BG | 1 |
| Dick, JE; Kong, EF; Krushinski, LE; Vannoy, KJ | 1 |
1 trial(s) available for caffeine and benzocaine
| Article | Year |
|---|---|
[Electric stimulation of the dental pulp in the evaluation of the central effect of analgesics].
Topics: Adult; Analgesics; Antipyrine; Benzocaine; Caffeine; Dental Pulp; Diphenhydramine; Diphenylacetic Acids; Dipyrone; Double-Blind Method; Drug Combinations; Drug Evaluation; Electric Stimulation; Ethylmorphine; Humans; Pain Measurement; Sensory Thresholds | 1990 |
18 other study(ies) available for caffeine and benzocaine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines | 2021 |
Relationship between caffeine effects and calcium in canine cardiac Purkinje fibers.
Topics: Action Potentials; Animals; Benzocaine; Caffeine; Calcium; Dogs; Electric Conductivity; Female; Heart; Heart Conduction System; Heart Rate; Kinetics; Male; Membrane Potentials; Myocardial Contraction; Procaine; Purkinje Fibers; Tetrodotoxin | 1985 |
Interaction of calcium and local anesthetics with skeletal muscle microsomes.
Topics: Anesthetics, Local; Animals; Benzocaine; Binding Sites; Caffeine; Calcium; Calcium Isotopes; Cell Membrane; Cell-Free System; Cytoplasmic Granules; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle Contraction; Muscles; Ouabain; Procaine; Quinidine; Rats; Sodium; Tetracaine | 1970 |
Release rates of solid drug mixtures dispersed in inert matrices. II. Mutually interacting drug mixtures.
Topics: Benzocaine; Caffeine; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Mathematics; Models, Theoretical; Pharmaceutic Aids; Polyethylenes; Polyvinyls; Solubility; Tablets | 1967 |
Determination of antipyrine in combinations with other drugs.
Topics: Antipyrine; Benzocaine; Caffeine; Chemistry, Pharmaceutical; Salicylates | 1965 |
Dissolution rates of polyphase mixtures.
Topics: Benzoates; Benzocaine; Caffeine; Chemistry, Pharmaceutical; Kinetics; Phosphates; Salicylates; Solubility | 1965 |
The effect of local anaesthetics on strophanthidin toxicity in canine cardiac Purkinje fibres.
Topics: Action Potentials; Animals; Benzocaine; Caffeine; Calcium; Dogs; Female; Heart Conduction System; In Vitro Techniques; Male; Myocardial Contraction; Norepinephrine; Procaine; Purkinje Fibers; Strophanthidin | 1981 |
Investigation of some complexes formed in solution by caffeine. IV. Interactions between caffeine and sulfathiazole, sulfadiazine, p-aminobenzoic acid, benzocaine, phenobarbital, and barbital.
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Barbital; Barbiturates; Benzocaine; Caffeine; Pharmaceutical Solutions; Phenobarbital; Solutions; Sulfadiazine; Sulfathiazole; Sulfathiazoles | 1954 |
Inhibition of hydrolysis of esters in solution by formation of complexes. I. Stabilization of benzocaine with caffeine.
Topics: Anesthetics; Anesthetics, Local; Benzocaine; Caffeine; Esters; Hydrolysis; Pharmaceutical Solutions; Solutions | 1955 |
Coupling desorption electrospray ionisation and neutral desorption/extractive electrospray ionisation with a travelling-wave based ion mobility mass spectrometer for the analysis of drugs.
Topics: Acetaminophen; Analgesics; Anti-Infective Agents, Local; Benzocaine; Caffeine; Chlorhexidine; Codeine; Dentifrices; Drug Combinations; Gels; Pharmaceutical Preparations; Polyethylene Glycols; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Predicting the excess solubility of acetanilide, acetaminophen, phenacetin, benzocaine, and caffeine in binary water/ethanol mixtures via molecular simulation.
Topics: Acetaminophen; Acetanilides; Benzocaine; Caffeine; Ethanol; Models, Molecular; Pharmaceutical Preparations; Phenacetin; Solubility; Solvents; Water | 2015 |
Thin layer chromatography coupled to paper spray ionization mass spectrometry for cocaine and its adulterants analysis.
Topics: Benzocaine; Caffeine; Chromatography, Thin Layer; Cocaine; Drug Contamination; Humans; Lidocaine; Mass Spectrometry; Narcotics; Phenacetin | 2016 |
Reagentless Voltammetric Identification of Cocaine from Complex Powders.
Topics: Benzocaine; Caffeine; Carbon Fiber; Cocaine; Levamisole; Lidocaine; Powders; Procaine; Water | 2022 |