caffeine has been researched along with acetaminophen in 517 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 134 (25.92) | 18.7374 |
| 1990's | 83 (16.05) | 18.2507 |
| 2000's | 125 (24.18) | 29.6817 |
| 2010's | 130 (25.15) | 24.3611 |
| 2020's | 45 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Botta, M; Dreassi, E; Falchi, F; Maga, G; Santucci, A; Schenone, S; Zizzari, AT | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Akamatsu, M | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Borges, F; Chavarria, D; Fernandes, C; Gil-Martins, E; Oliveira, PJ; Remião, F; Silva, C; Silva, R; Silva, T; Silva, V; Soares, P | 1 |
| Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A | 1 |
| Miller, RR | 1 |
| Jager, LP; Seegers, AJ; Van Noordwijk, J | 2 |
| Adamkov, J; Bevilaqua, L; Drobný, M; Fundárek, J; Knéslová, L; Pithová, B; Wolfová, E | 1 |
| Flores-Mercado, F; Gallegos-Torres, J | 1 |
| Fozard, JR | 1 |
| Lawczyński, L; Olszewska, M; Samochowiec, L; Szwed, G; Wójcicki, J | 1 |
| Kagan, G; Masheter, HC | 1 |
| Atkinson, D | 1 |
| Dressler, F | 1 |
| Alberola, S; Jeanjean, B; Sabon, F; Terol, A | 1 |
| Baum, RG; Cantwell, FF | 1 |
| Somerville, BW | 1 |
| León Díaz, C | 1 |
| Borges, J; Zavaleta, C | 1 |
| Bare, WW; Berry, FN; Levin, HM; Miller, JM; Smith, MT | 1 |
| Le Roux, PA | 1 |
| Cotty, VF; Ederma, H; Hunter, D; Lehr, M; Melman, K; Mueller, F; Skerpac, J; Sterbenz, FJ | 1 |
| Ebel, S; Herold, G | 1 |
| Harnisch, H; Lincke, U | 1 |
| Gallery, E; Mahony, JF; McCarthy, SW; Roberts, BA; Stewart, JH; Storey, BG | 1 |
| Balinsky, D; Cayanis, E; Disler, P; Gomperts, ED; Myers, A | 1 |
| Axelsen, RA | 1 |
| Wilkinson, M | 2 |
| Chen, ZX; Cheng, XM; Li, HL | 1 |
| Castañeda-Hernández, G; Flores-Murrieta, FJ; Granados-Soto, V; López-Muñoz, FJ | 1 |
| Dutkiewicz, T; Juzwiak, S; Juzyszyn, Z; Krasowska, B; Olenderek, B; Raińska, T; Roźéwicka, L; Samochowiec, L; Wójcicki, J | 1 |
| Carroll, D; Guest, P; Juniper, RP; McQuay, HJ; Moore, RA | 1 |
| Kamiyama, T; Liu, J; Marumo, F; Miyakawa, H; Sato, C; Shigesawa, T; Tajiri, K | 1 |
| Michaelis, HC; Schoel, G; Sharifi, S | 1 |
| Ersoy, L; Sungur, S; Yurdakul, G | 1 |
| Lyall, JB | 1 |
| Adusumilli, PS; Aloba, OT; Nigalaye, AG | 1 |
| Brown, A; Chaing, DS; Konerman, JP; Schachtel, BP; Thoden, WR | 1 |
| Collste, P | 1 |
| Gayawali, K; Pandhi, P; Sharma, PL | 1 |
| Brenner, S; Dascalu, D; Hodak, E; Lurie, R; Wolf, R | 1 |
| Elkind, AH | 1 |
| Avery, D; Dunner, D; Ward, N; Whitney, C | 1 |
| Aboul Khier, A; el Sadek, M; el Shanawany, A; Rücker, G | 1 |
| Habib, S; Levers, BG; Matthews, RW; Scully, C; Shepherd, JP | 1 |
| Kalhorn, TF; Lee, CA; Nelson, SD; Slattery, JT | 1 |
| Fukuyama, T; Matsuo, M; Nishi, H; Terabe, S | 1 |
| Blyth, DA; Eiceman, GA; Shoff, DB; Snyder, AP | 1 |
| Avramova, J | 1 |
| Autret, E; Breteau, M; Furet, Y; Jonuille, AP; Maizoub, S; Rossazza, C | 1 |
| Cheung, YM; Lau, OW; Luk, SF | 1 |
| Abrahamsen, A; Førre, O; Kåss, E; Vaerøy, H | 1 |
| Izumi, N; Sato, C | 1 |
| Clerc, JT; Kosmeas, N | 1 |
| Tománková, H; Vasatová, M | 1 |
| Cockaerts, P | 1 |
| Bamford, CR; Gillman, MA; Sandyk, R | 1 |
| Autret, E; Breteau, M; Furet, Y; Jonville, AP; Majzoub, S; Rossazza, C | 1 |
| Verbov, J | 1 |
| DiSerio, FJ; Friedman, AP | 1 |
| Gale, GR; Smith, AB | 1 |
| Ford, D; Meatherall, R | 1 |
| Osterloh, J; Yu, S | 1 |
| Bauer, M; Bauerová, J; Bojar, Z; Dobrotka, G; Marsinová, G | 1 |
| Gundersen, R; Høivik, HO; Osmundsen, K | 1 |
| Gale, GR; Price, VF | 1 |
| Gupta, D; Jain, A; Sanghi, SK; Verma, KK | 1 |
| Atkins, LM; Gale, GR; Smith, AB; Walker, EM | 1 |
| Johansson, G; Laakso, ML; Lindroos, F | 1 |
| Gusdorf, CF; Sitsen, JM; Tukker, JJ | 1 |
| Luo, GA; Luo, Z; Wang, YM | 1 |
| Atkins, LM; Gale, GR; Lamar, C; Smith, AB; Walker, EM | 1 |
| Bird, HA | 1 |
| Bloch, B; Smythe, E; Weeks, R | 1 |
| Hasumura, Y; Izumi, N; Nouchi, T; Sato, C; Takeuchi, J | 1 |
| Clyne, MJ; Middleton, RS | 1 |
| Mamolo, MG; Maurich, V; Vio, L | 1 |
| Barciulli, F; Cosentina, R | 1 |
| Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ | 1 |
| Beyrich, T; Schleuder, M | 1 |
| Prescott, LF | 2 |
| Cantor, M | 1 |
| Bonnamour, C; Peaud, PY; Plauchu, M | 1 |
| Rosenbaum, D | 1 |
| Booy, RH | 1 |
| Flores Mercado, F; Gallegos Torres, J | 1 |
| Messerich, J | 1 |
| Doutre, LP; Périssat, J | 1 |
| Arnold, L; Collins, C; Starmer, GA | 1 |
| Jurand, J; Knox, JH | 1 |
| Siegers, CP | 1 |
| Naess, K | 1 |
| Buytendijk, HJ; Maesen, F | 1 |
| Thorpe, P | 2 |
| Wohlzogen, FX | 2 |
| Karapandzic, M; Obradovic, V; Piscevic, A; Poznic, M | 1 |
| Baechtold-Fowler, N; Bonjour, JP; Chométy-Diézi, F; Filloux, B; Guidoux, R; Guignard, JP; Hedinger, C; Peters, G; Peters-Haefeli, L; Roch-Ramel, F; Schelling, JL; Weber, E | 1 |
| Götz, K | 1 |
| Gabe, A; Gault, MH; Shahidi, NT | 1 |
| Chow, YP; Repta, AJ | 1 |
| Boyd, EM | 2 |
| Ahmed, I; Olowe, O | 1 |
| Bagnasco, G; Cometti, A; Maggi, N | 1 |
| Burtis, CA; Stevenson, RL | 1 |
| Alber, LL; Overton, MW; Smith, DE | 1 |
| Martins, HT | 1 |
| Kincaid-Smith, P | 1 |
| Kalatzis, E | 1 |
| Miele, D; Shane, N | 1 |
| Abel, JA; Miley, RA | 1 |
| Gerbold, H | 1 |
| Kowblansky, M; Shane, N | 1 |
| Koibuchi, M; Minamikawa, T; Nishimura, Y; Shibazaki, T | 1 |
| Guillory, JK; Hwang, SC; Lach, JL | 1 |
| Dikstein, S; Grotto, M; Sulman, FG | 1 |
| Felber, R | 1 |
| McMartin, C; Street, HV | 1 |
| Johansson, S | 1 |
| Ananian, V; MacKay, IS | 1 |
| Bradshaw, AJ; Edmondson, HD | 1 |
| Frawley, VL; Ou, CN | 1 |
| Middleton, RS | 1 |
| Deng, JF; Rall, TW; Spyker, DA; Steward, O | 1 |
| Elvers, WB; Laska, EM; Mueller, F; Rubin, A; Siegel, C; Sunshine, A | 1 |
| Sturrock, RD | 1 |
| Beaver, WT | 2 |
| Rubin, A; Winter, L | 1 |
| Boston, PF | 1 |
| Bruno, VF; De Ritis, G; De Rossi, P; De Tommaso, G; Granato, C; Lotti, A; Morabito, F; Nola, P; Pozzessere, C; Roscioni, C | 1 |
| Derendorf, H; Elger, CE; Knoll, O; Rohdewald, P | 1 |
| Laska, EM; Marrero, I; Olson, N; Roure, C; Sunshine, A; Wanderling, J; Zighelboim, I | 1 |
| Cunningham, B; Dougall, JR; Nimmo, WS | 1 |
| Ladwa, RA | 1 |
| Strunin, L; White, P | 1 |
| Even-Adin, D; Vanherweghem, JL | 1 |
| Bannister, SJ; Snyder, LR; van der Wal, S | 1 |
| Mettler, L; Sadighi, R | 1 |
| Maier-Lenz, H; Ringwelski, L; Windorfer, A | 1 |
| DeAngelis, RL; Findlay, JM; Findlay, JW; Kearney, MF; Welch, RM | 1 |
| Schenk, GH; Street, KW | 1 |
| Johansson, SL | 1 |
| Das Gupta, V | 1 |
| Jager, LP; Olling, M; Seegers, JM; Van Noordwijk, J | 1 |
| Daniel, V; Howard, M; Nanra, RS | 1 |
| Thoma, E; Thoma, H | 1 |
| Elsayed, MA; Ogbonnia, OS | 1 |
| Loft, S; Poulsen, HE; Roberts, DW; Thomsen, MS | 1 |
| Hanusz, Z | 1 |
| Monshouwer, M; Nijmeijer, SM; Pijpers, A; Van Miert, AS; Verheijden, JH; Witkamp, RF | 1 |
| Ahmad, B; Gilani, AU; Iqbal, N; Janbaz, KH; Niazi, SK | 1 |
| Kleinknecht, D | 1 |
| Luksa, J; Marusic, A | 1 |
| Chen, A; Lunte, CE | 1 |
| Armellino, JJ; Beaver, WT; Friedman, M; Gillings, DB; Migliardi, JR | 1 |
| Bock, KW; Brockmeier, D; Eichelbaum, M; Forster, A; Griese, EU; Mörike, K; Schrenk, D | 1 |
| Castañeda-Hernández, G; Flores-Murrieta, FJ; Granados-Soto, V; López-Muñoz, FJ; Salazar, LA; Villarreal, JE | 1 |
| Abdel-Meguid, EM; Farag, MM | 1 |
| Fang, XG; Ghodbane, S; Shen, P; Thomas, BR | 1 |
| Kaa, E | 1 |
| Kondo, T; Lin, Z; Nagano, T; Nakaya, T; Nishigami, J; Ohshima, T; Sawaguchi, T; Takayasu, T | 1 |
| Hamada, H; Hiwada, K; Inoue, Y; Kohno, N; Kondo, K; Yokoyama, A | 1 |
| Jaw, S; Jeffery, EH | 1 |
| Lee, CA; Lillibridge, JH; Nelson, SD; Slattery, JT | 1 |
| Raińska-Giezek, T | 1 |
| Aicher, B; Kraupp, O | 1 |
| Wu, C; Zhao, H; Zhou, Z | 1 |
| Engelhardt, G | 1 |
| Engelhardt, G; Homma, D | 1 |
| Adriani, Y; Indrayanto, G; Sunarto, A | 1 |
| Bauer, E; Bauer, M; Greischel, A; Hirsch, U; Lehmann, H; Schmid, J; Schneider, P | 1 |
| Li Wan Po, A; Zhang, WY | 1 |
| Doğan, HN | 1 |
| Brossel, R; Kuntz, D | 1 |
| Hsiao, ML; Huang, WF; Wen, KC | 1 |
| Carrive, P; Meyer-Carrive, I | 1 |
| Schwarz, A | 1 |
| Hörl, WH | 1 |
| Danilov, AB; Vornovskaia, OV | 1 |
| Iñiguez, C; Larrodé, P; Mauri, JA; Morales, F | 1 |
| Casley, WL; Girard, M; Menzies, JA; Moon, TW; Mousseau, N; Whitehouse, LW | 1 |
| Engelhardt, G; Mauz, AB; Pairet, M | 1 |
| Amelin, AV; Sorokoumov, VA | 1 |
| Evglevskaia, IuP; Minkin, LN; Zuev, VP | 2 |
| Casley, WL; Girard, M; Larocque, L; Menzies, JA; Moon, TW; Mousseau, N; Whitehouse, LW | 1 |
| Danilov, AB; Poliakova, LV; Tuter, NV | 1 |
| Strong, FC | 1 |
| Lipton, RB; Ryan, RE; Saper, J; Sheftell, F; Silberstein, S; Stewart, WF | 1 |
| Amidon, GE; Amidon, GL; Barnett, JL; Frens, J; Hayashi, Y; Putcha, L; Rhie, JK; Wald, RJ; Welage, LS | 1 |
| Aicher, B; Baumeister, M | 1 |
| Barrett, BJ; Gault, MH | 1 |
| Kriukov, AI; Kunel'skaia, NL; Ogorodnikov, DS; Pal'chun, VT; Uzdennikov, AA; Vladimirova, VV | 1 |
| Aichmüller, C; Schütz, C; Soyka, M | 1 |
| Bach, PH; Berndt, WO; Delzell, E; Dubach, U; Finn, WF; Fox, JM; Hess, R; Michielsen, P; Sandler, DP; Trump, B; Williams, G | 1 |
| Hintze, R; Karaus, M; Naumann, MG | 1 |
| Maizels, M | 1 |
| Albert, K; Bayer, E; Gfrörer, P; Pusecker, K; Schewitz, J; Tseng, LH | 1 |
| Armellino, JJ; Battikha, JP; Hamelsky, SW; Hoffman, HD; Lipton, RB; Silberstein, SD; Stewart, WF | 1 |
| Corneillie, M; Stevens, E; Van Assche, A; Van de Velde, M; Vanacker, B; Vandermeersch, E; Verhaeghe, J | 1 |
| Dabek-Zlotorzynska, E; Lai, EP | 1 |
| Armellino, JJ; Battikha, JP; Blumenthal, H; Couch, J; Goldstein, J; Hamelsky, SW; Hoffman, HD; Lipton, RB | 1 |
| Dinç, E | 2 |
| Fernandez de Córdova, ML; Molina-Diaz, A; Ruiz Medina, A | 1 |
| Bebawy, LI; El-Kousy, NM | 1 |
| Forte, LV; Galvão, AC; Rabello, GD | 1 |
| Opletal, L; Sladkovský, R; Solich, P | 1 |
| Asahi, M; Kobayashi, M; Yamamoto, O; Yasuda, H | 1 |
| Aicher, B; Engelhardt, G; Fiebich, BL; Hüll, M; Lieb, K; Pairet, M; van Ryn, J | 1 |
| See, IO | 1 |
| Kitamura, R; Kusunose, S; Matsuoka, Y; Nakamura, K; Ogino, Y | 1 |
| Curhan, GC; Delzell, E; Deschepper, PJ; Feinstein, AR; Fox, JM; Graf, H; Heinemann, LA; Luft, FC; Michielsen, P; Mihatsch, MJ; Suissa, S; Van Der Woude, F; Willich, S | 1 |
| Evans, RW | 1 |
| Burg, MB; Ferguson, DR; Kirby, M; Michea, LF; Peters, EM; Rocha, GM; Xu, Y | 1 |
| Guo, X; Qian, W; Yang, C; Zhu, X | 1 |
| Denton, MB; Liang, Y; Simon, RE; Walton, LK | 1 |
| Czégány, Z; Harsányi, J; Homoki, M; Kassai, M; Kiss, E; Kiss, I; Ladányi, E; Lócsey, L; Major, L; Mátyus, J; Misz, M; Nagy, J; Nagy, L; Pintér, I; Polner, K; Pótó, L; Rédl, J; Solt, I; Tichy, B; Török, M; Varga, G; Wagner, G; Wittmann, I; Wórum, I; Zsoldos, B | 1 |
| Boobis, AR; Edwards, RJ; Murray, BP; Murray, S; Odupitan, AO | 1 |
| Dinç, E; Kökdil, G; Onur, F | 1 |
| Kartal, M | 1 |
| Abou-Donia, MB; Abu-Qare, AW | 1 |
| Baleanu, D; Dinç, E; Onur, F | 1 |
| Amidon, GE; Amidon, GL; Barnett, JL; Choe, SY; Neudeck, BL; Welage, LS | 1 |
| Gui, CQ; Sun, RY; Wang, XW; Zheng, QS | 1 |
| Gore, MA; Morshedi, MM; Reidhaar-Olson, JF | 1 |
| Llobat-Estellés, M; Pascual-Martí, MC; Roig-Marco, MI | 1 |
| Baleanu, D; Dinç, E | 1 |
| Burdan, F; Siezieniewska, Z; Urbanowicz, Z | 1 |
| Bi, K; Dai, R; Luo, X; Wang, X | 1 |
| Moral Turiel, M; Rodríguez Simón, MO; Sahagún de la Lastra, J; Yuste Pascual, JA | 1 |
| Burdan, F | 2 |
| Agbaba, D; Aleksic, M; Eric, S; Franeta, JT; Pavkov, S; Vladimirov, S | 1 |
| Kutter, JP; Mogensen, KB; Petersen, NJ | 1 |
| Molina-Díaz, A; Ortega-Barrales, P; Padilla-Weigand, R | 1 |
| Rollins, G | 1 |
| Bement, J; Chatfield, K; DiPetrillo, K; Jeffery, E; Kostrubsky, V; Sinclair, J; Sinclair, P; Wood, S; Wrighton, S | 1 |
| Berenbeim, D; Burk, CT; Gilderman, A; Nichol, MB; Salas, J | 1 |
| Burg, MB; Cai, Q; Dmitrieva, NI; Ferguson, D; Michea, LF; Rocha, G | 1 |
| Alken, RG; Bacratcheva, N; Gawronska-Szklarz, B; Giesel, B; Koytchev, R; Mrozikiewiczs, A; van der Meer, M; Vlahov, V; Wojcicki, J | 1 |
| Yildirim, RC | 1 |
| Su, WT; Tang, X; Wu, XH; Zhang, LQ; Zhu, XL | 1 |
| Zhang, J; Zhang, XS | 1 |
| SIEGWAN, NA | 1 |
| AVIADO, DM; SALEM, H | 1 |
| KOSHY, KT | 1 |
| Jarmalaviciene, R; Kornysova, O; Maruska, A; Westerlund, D | 1 |
| Poppi, RJ; Sena, MM | 1 |
| KRISCHEK, J | 1 |
| Ivanovic, D; Jancic, B; Malenovic, A; Medenica, M; Misljenovic, Dj | 1 |
| Ju, H; Shi, X; Yuan, Z; Zhang, D | 1 |
| Fanali, S; Mandrioli, R; Pucci, V; Raggi, MA | 1 |
| Fraker, SL; Smith, GR | 1 |
| Baron, JD; Hinchey, JA; Knox, AP; Romero, CE; Ropper, AH | 1 |
| Beebe, DK; Cook, JW; Jafri, SH; Reed, RR | 1 |
| Araújo, AN; Conceição, M; Montenegro, BS; Neto, I; Satínský, D; Sklenákova, H; Solich, P | 1 |
| Mao, YQ; Mu, ZX; Zhang, YF | 1 |
| Brain, RA; Hanson, ML; Johnson, DJ; Lam, MW; Mabury, SA; Richards, SM; Sanderson, H; Sibley, PK; Solomon, KR; Young, C | 1 |
| Pistos, C; Stewart, JT | 1 |
| Eriksson, F; Gustafsson, O; Kutter, JP; Mogensen, KB; Nikolajsen, RP | 1 |
| Akpinar, H; Esmaoglu, A; Uğur, F | 1 |
| Deibel, MA; Ford, MJ; Van Berkel, GJ | 1 |
| Hara, H; Yokoyama, A | 1 |
| Koundourellis, JE; Malliou, ET; Markopoulou, CK | 1 |
| Dinç, E; Ozdemir, A | 1 |
| Cai, YM; Cao, D; Huang, XR; Tai, Y | 1 |
| Almas, M; Hilliard, B; Loder, E; Martin, VT; Taylor, K | 1 |
| Baggish, J; Battikha, JP; Elkind, AH; Gallagher, RM; Goldstein, J; Hoffman, H; Saper, JR; Silberstein, SD; Smith, TR | 1 |
| Court, MH; Duan, SX; Evans, RM; Greenblatt, DJ; Hao, Q; Hunt, JA; Jeffery, EH; Lan, L; Schuetz, EG; Sinclair, JF; Sinclair, PR; Szakacs, JG; von Moltke, LL; Walton-Strong, BW; Wolf, KK; Wood, SG; Wrighton, SA; Yasuda, K | 1 |
| Aicher, B; Diener, HC; Pageler, L; Peil, H; Pfaffenrath, V | 2 |
| Croker, B; Ejaz, AA; Johnson, RJ; Munjal, S; Sekhon, I | 1 |
| Charlier, C; Denooz, R; Dubois, N | 1 |
| Alcalá, M; Blanco, M | 1 |
| Burgett, AA; Smith, GR | 1 |
| Clarke, GD; Godfrey, L; Hourani, SM; Kitchen, I; Ledent, C; Yan, L | 1 |
| Bigal, ME; Rapoport, AM; Sheftell, FD; Tepper, SJ; Volcy, M | 1 |
| Blumenthal, HJ; Diamond, ML | 1 |
| Wenzel, RG | 1 |
| Aicher, B; Akundi, RS; Candelario-Jalil, E; Fiebich, BL; Finkenzeller, G; Heinzmann, M; Hüll, M; Knörle, R; Mantovani, M; Schnierle, P | 1 |
| Cooks, RG; Mulligan, CC; Talaty, N | 1 |
| Goldstein, J; Lipton, RB; Ryan, RE; Saper, JR; Silberstein, SD | 1 |
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| Abdelouahab, N; Baccarelli, AA; Bellenger, JP; Bloomquist, TR; Brennan, KJM; Burris, HH; Cassoulet, R; Coull, BA; Desautels, AS; Gillet, V; Laue, HE; Shen, Y; Takser, L; Weisskopf, MG; Wilkie, E; Wu, H; Zhang, W | 1 |
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| Araya-Valverde, E; Balcázar, JL; Briceño-Guevara, S; Cambronero-Heinrichs, JC; Masis-Mora, M; Mendez-Rivera, M; Montiel-Mora, JR; Ramírez-Morales, D; Rodríguez-Rodríguez, CE; Sànchez-Melsió, A; Soto-Garita, C | 1 |
| Masís-Mora, M; Méndez-Rivera, M; Montiel-Mora, JR; Ramírez-Morales, D; Rodríguez-Rodríguez, CE | 1 |
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21 review(s) available for caffeine and acetaminophen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Propoxyphene: a review.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Chemical Phenomena; Chemistry; Dextropropoxyphene; Drug Combinations; Drug Incompatibility; Heroin Dependence; Humans; Kinetics; Phenacetin; Substance-Related Disorders | 1977 |
The animal pharmacology of drugs used in the treatment of migraine.
Topics: Acetaminophen; Adrenergic alpha-Antagonists; Analgesics; Animals; Aspirin; Caffeine; Clonidine; Cyproheptadine; Dihydroergotamine; Ergotamine; Humans; Methysergide; Migraine Disorders; Monoamine Oxidase Inhibitors; Muscle, Smooth; Pizotyline; Serotonin Antagonists; Sympathetic Nervous System; Synaptic Transmission; Tryptamines; Vagus Nerve; Vasoconstrictor Agents; Vasodilator Agents | 1975 |
Interstitial nephritis, the nephrotic syndrome, and chronic renal failure secondary to nonsteroidal anti-inflammatory drugs.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Humans; Kidney Failure, Chronic; Nephritis, Interstitial; Nephrotic Syndrome | 1995 |
[Effectiveness of fixed analgesic combinations exemplified by thomapyrin].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Germany; Humans; Pain; Pain Measurement; Product Surveillance, Postmarketing; Treatment Outcome | 1996 |
Analgesic efficacy of paracetamol and its combination with codeine and caffeine in surgical pain--a meta-analysis.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Caffeine; Codeine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Pain, Postoperative; Randomized Controlled Trials as Topic; Regression Analysis | 1996 |
Analgesic nephropathy.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Canada; Drug Combinations; Drug Synergism; Humans; Kidney Failure, Chronic; Phenacetin; Risk Factors; United States | 1998 |
A safety assessment of fixed combinations of acetaminophen and acetylsalicylic acid, coformulated with caffeine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Drug Combinations; Humans; Kidney Failure, Chronic; Risk | 1998 |
Relationship between nonphenacetin combined analgesics and nephropathy: a review. Ad Hoc Committee of the International Study Group on Analgesics and Nephropathy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Drug Combinations; Humans; Kidney Failure, Chronic; Phenacetin; Phosphodiesterase Inhibitors | 2000 |
ANTITUSSIVE DRUGS, WITH SPECIAL REFERENCE TO A NEW THEORY FOR THE INITATION OF THE COUGH REFLEX AND THE INFLUENCE OR BRONCHODILATORS.
Topics: Acetaminophen; Aerosols; Aminophylline; Analgesics; Analgesics, Non-Narcotic; Animals; Antimony; Antipyretics; Antitussive Agents; Ascorbic Acid; Bronchodilator Agents; Caffeine; Codeine; Cough; Dogs; Electric Stimulation; Electrophysiology; Expectorants; Histamine H1 Antagonists; Hypnotics and Sedatives; Ion Exchange Resins; Noscapine; Parasympatholytics; Pharmacology; Phenothiazines; Promethazine; Reflex; Research; Sodium Salicylate; Sympathomimetics | 1964 |
[Self-medication of migraine and headache].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Controlled Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Evaluation Studies as Topic; Humans; Ibuprofen; Migraine Disorders; Practice Guidelines as Topic; Self Medication; Serotonin Receptor Agonists; Sumatriptan; Tablets; Tension-Type Headache; Vasoconstrictor Agents | 2006 |
Efficacy of fixed combinations of acetylsalicyclic acid, acetaminophen and caffeine in the treatment of idiopathic headache: a review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Caffeine; Drug Combinations; Humans; Tension-Type Headache | 2010 |
A risk-benefit assessment of paracetamol (acetaminophen) combined with caffeine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Caffeine; Central Nervous System Stimulants; Databases, Factual; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Liver; Pain; Risk Assessment; Treatment Outcome | 2010 |
Methylxanthines and pain.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Drug Interactions; Humans; Morphine; Pain | 2011 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Caffeine; Chemotherapy, Adjuvant; Female; Headache; Humans; Ibuprofen; Pain, Postoperative; Postpartum Period; Pregnancy; Randomized Controlled Trials as Topic | 2012 |
Beta2-adrenoceptor agonists for dysmenorrhoea.
Topics: Acetaminophen; Adolescent; Adrenergic beta-2 Receptor Agonists; Adult; Caffeine; Dysmenorrhea; Female; Humans; Isoxsuprine; Metaproterenol; Randomized Controlled Trials as Topic; Ritodrine; Terbutaline; Young Adult | 2012 |
Combined butalbital/acetaminophen/caffeine overdose: case files of the Robert Wood Johnson Medical School Toxicology Service.
Topics: Acetaminophen; Acetylcysteine; Adult; Barbiturates; Caffeine; Drug Combinations; Drug Overdose; Female; Hemoperfusion; Humans; Renal Dialysis; Treatment Outcome; Vasopressins; Xanthines | 2012 |
Use of a fixed combination of acetylsalicylic acid, acetaminophen and caffeine compared with acetaminophen alone in episodic tension-type headache: meta-analysis of four randomized, double-blind, placebo-controlled, crossover studies.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; Humans; Pain Measurement; Tension-Type Headache; Treatment Outcome | 2014 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Analgesics; Caffeine; Chemotherapy, Adjuvant; Diclofenac; Drug Synergism; Dysmenorrhea; Female; Headache; Humans; Ibuprofen; Male; Middle Aged; ortho-Aminobenzoates; Pain, Postoperative; Postpartum Period; Pregnancy; Randomized Controlled Trials as Topic | 2014 |
Caffeine in the management of patients with headache.
Topics: Abdominal Pain; Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Central Nervous System Stimulants; Headache; Humans; Ibuprofen; Migraine Disorders; Randomized Controlled Trials as Topic; Tension-Type Headache | 2017 |
Aspirin, paracetamol (acetaminophen) and caffeine for the treatment of acute migraine attacks: A systemic review and meta-analysis of randomized placebo-controlled trials.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Humans; Migraine Disorders; Randomized Controlled Trials as Topic | 2022 |
80 trial(s) available for caffeine and acetaminophen
| Article | Year |
|---|---|
[Effectiveness of fenalgin SPOFA in lumboischiadic syndrome (author's transl)].
Topics: Acetaminophen; Adult; Aspirin; Back Pain; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Drug Combinations; Female; Humans; Male; Middle Aged; Phenobarbital; Sciatica; Syndrome | 1979 |
Isoxsuprine in primary dysmenorrhoea. Its effectiveness in premenstrual tension.
Topics: Acetaminophen; Adolescent; Adult; Caffeine; Double-Blind Method; Drug Combinations; Dysmenorrhea; Female; Humans; Isoxsuprine; Premenstrual Syndrome | 1975 |
A double-blind comparative evaluation of aspirin, paracetamol and paracetamol + caffeine (finimal) for their analgesic effectiveness.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Headache; Humans; Male; Middle Aged; Pain, Postoperative | 1977 |
A controlled study of short-term treatment of tension headache.
Topics: Acetaminophen; Adult; Analgesics; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Doxylamine; Drug Combinations; Female; Headache; Humans; Male; Middle Aged; Placebos; Stress, Psychological; Time Factors | 1978 |
A single dose placebo-controlled study to assess the effectiveness of adding a muscle relaxant to a compound analgesic in the treatment of tension headache.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Caffeine; Chlormezanone; Clinical Trials as Topic; Codeine; Drug Combinations; Drug Therapy, Combination; Female; Headache; Humans; Male; Middle Aged; Muscle Relaxants, Central; Placebos | 1979 |
Treatment of migraine attacks with an analgesic combination (Mersyndol).
Topics: Acetaminophen; Acute Disease; Caffeine; Clinical Trials as Topic; Codeine; Doxylamine; Drug Combinations; Humans; Migraine Disorders; Placebos; Pyridines | 1976 |
[Evaluation of a new analgesic combination in the control of pain in different odontological processes].
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Caffeine; Clinical Trials as Topic; Dextropropoxyphene; Drug Combinations; Drug Evaluation; Female; Humans; Hydroxyzine; Male; Middle Aged; Tablets; Toothache | 1976 |
Study of a new analgesic compound in the treatment of tension headache.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Caffeine; Clinical Trials as Topic; Dextropropoxyphene; Drug Combinations; Drug Evaluation; Female; Headache; Humans; Hydroxyzine; Male; Middle Aged | 1976 |
Acetaminophen extra strength capsules versus propoxphene compound-65 versus placebo: a double-blind study of effectiveness and safety.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Caffeine; Capsules; Clinical Trials as Topic; Dextropropoxyphene; Drug Combinations; Episiotomy; Female; Humans; Pain; Placebos; Pregnancy | 1975 |
The analgesic effect of Syndol following neurosurgery and neurosurgical procedures.
Topics: Acetaminophen; Adult; Caffeine; Clinical Trials as Topic; Codeine; Doxylamine; Drug Combinations; Female; Humans; Male; Neurosurgery; Pain, Postoperative; Pyridines; Time Factors | 1975 |
[Double-blind study on the comparative effects of phenazetin and parazetamol in an analgetics combination].
Topics: Acetaminophen; Analgesics; Caffeine; Drug Combinations; Drug Evaluation; Humans; Phenazines; Vitamin B Complex | 1975 |
A multiple dose comparison of combinations of ibuprofen and codeine and paracetamol, codeine and caffeine after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Caffeine; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Molar, Third; Pain Measurement; Pain, Postoperative | 1992 |
Third molar surgery: the effect of primary closure, wound dressing and metronidazole on postoperative recovery.
Topics: Acetaminophen; Adult; Analgesics; Bandages; Bismuth; Caffeine; Codeine; Drug Combinations; Female; Humans; Hydrocarbons, Iodinated; Male; Metronidazole; Molar, Third; Pain, Postoperative; Surgical Wound Infection; Suture Techniques; Sutures; Tooth, Impacted; Wound Healing | 1991 |
Headache pain model for assessing and comparing the efficacy of over-the-counter analgesic agents.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Headache; Humans; Male; Medical History Taking; Middle Aged; Models, Biological; Nonprescription Drugs | 1991 |
The analgesic effects of caffeine in headache.
Topics: Acetaminophen; Adolescent; Adult; Affect; Caffeine; Double-Blind Method; Drug Combinations; Female; Headache; Humans; Male; Middle Aged; Pain Measurement | 1991 |
A study of the comparative efficacy of four common analgesics in the control of postsurgical dental pain.
Topics: Acetaminophen; Adult; Analgesics; Analysis of Variance; Aspirin; Caffeine; Codeine; Drug Combinations; Female; Humans; Ibuprofen; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Random Allocation; Single-Blind Method; Tooth Extraction; Tooth, Impacted | 1990 |
Treatment of fibromyalgia (fibrositis syndrome): a parallel double blind trial with carisoprodol, paracetamol and caffeine (Somadril comp) versus placebo.
Topics: Acetaminophen; Adult; Aged; Caffeine; Carisoprodol; Clinical Trials as Topic; Double-Blind Method; Female; Fibromyalgia; Humans; Middle Aged; Physical Stimulation; Pressure; Sensory Thresholds | 1989 |
Symptomatic treatment of chronically recurring tension headache: a placebo-controlled, multicenter investigation of Fioricet and acetaminophen with codeine.
Topics: Acetaminophen; Adult; Barbiturates; Caffeine; Chronic Disease; Clinical Trials as Topic; Consumer Behavior; Double-Blind Method; Drug Combinations; Female; Headache; Humans; Male; Middle Aged; Random Allocation | 1987 |
[Combined analgesics in myalgia of the neck. A double-blind comparison of paracetamol and orphenadrine (Norgesic) and paracetamol and codeine (Paralgin forte) in general practice].
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Muscles; Neck Muscles; Orphenadrine; Pain | 1986 |
Analgesics for pain relief after gynaecological surgery. A two-phase study.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Benzophenones; Caffeine; Clinical Trials as Topic; Codeine; Dipyrone; Double-Blind Method; Drug Combinations; Female; Humans; Hysterectomy; Injections, Intramuscular; Meperidine; Meprobamate; Pain, Postoperative; Piperidines; Random Allocation; Smoking; Time Factors | 1985 |
A comparative study of Propain and a dextropropoxyphene/paracetamol combination analgesic.
Topics: Acetaminophen; Adolescent; Adult; Aged; Caffeine; Codeine; Dextropropoxyphene; Diphenhydramine; Drug Combinations; Female; Humans; Male; Middle Aged; Pain | 1985 |
[Pain relief with simple analgesics in dentistry].
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Dry Socket; Heterocyclic Compounds; Humans; Pain Management; Placebos; Tooth Extraction | 1972 |
[Use of Mesindol in dysmenorrhea].
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Atropine; Caffeine; Clinical Trials as Topic; Drug Combinations; Dysmenorrhea; Female; Humans; Placebos; Salicylamides | 1972 |
[EMA 3--a phenacetin-free combination with analgesic action].
Topics: Acetaminophen; Adult; Aged; Allyl Compounds; Analgesics; Barbiturates; Caffeine; Clinical Trials as Topic; Drug Combinations; Evaluation Studies as Topic; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Pain; Phenacetin; Thioridazine | 1973 |
[Double blind testing of the analgesic CIBA AA 200 in comparison with another analgesic and a placebo].
Topics: Acetaminophen; Aspirin; Caffeine; Clinical Trials as Topic; Humans; Placebos | 1968 |
Controlled and uncontrolled studies on "Fiorinal-PA" for symptomatic relief in tension headache.
Topics: Acetaminophen; Aspirin; Barbiturates; Caffeine; Clinical Trials as Topic; Drug Synergism; Headache; Humans; Hypnotics and Sedatives; Phenacetin; Placebos | 1970 |
Method, design, and analysis of a comparative study of analgetics.
Topics: Acetaminophen; Analgesics; Analysis of Variance; Caffeine; Clinical Trials as Topic; Humans; Pain; Placebos; Reaction Time; Thioridazine | 1970 |
Method, design, and analysis of a comparative study of analgetics.
Topics: Acetaminophen; Analgesics; Analysis of Variance; Caffeine; Clinical Trials as Topic; Humans; Pain; Placebos; Reaction Time; Thioridazine | 1970 |
[EMA 3--a new combined analgesic].
Topics: Acetaminophen; Adult; Aged; Analgesics; Caffeine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Thioridazine | 1970 |
An assessment of "Fiorinal" and FIPA in painful conditions of the hands.
Topics: Acetaminophen; Adult; Aged; Analgesics; Analysis of Variance; Arthritis, Rheumatoid; Aspirin; Caffeine; Drug Synergism; Hand; Humans; Middle Aged; Osteoarthritis; Pain; Phenacetin; Placebos | 1970 |
Analgesia following adult tonsillectomy: a comparative study of solpadeine and a soluble form of dextropropoxyphene napsylate and paracetamol.
Topics: Acetaminophen; Adult; Aged; Analgesics; Caffeine; Codeine; Dextropropoxyphene; Drug Combinations; Drug Tolerance; Female; Humans; Male; Middle Aged; Pain, Postoperative; Solubility; Tonsillectomy | 1982 |
Analgesia following oral surgery: a comparative study of Solpadeine and a soluble form of dextropropoxyphene napsylate and paracetamol.
Topics: Acetaminophen; Adolescent; Adult; Caffeine; Codeine; Dextropropoxyphene; Drug Combinations; Female; Humans; Male; Middle Aged; Molar, Third; Pain; Random Allocation; Tooth Extraction | 1983 |
A comparison of two analgesic muscle relaxant combinations in acute back pain.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Aspirin; Back Pain; Caffeine; Carisoprodol; Chlormezanone; Clinical Trials as Topic; Diclofenac; Drug Combinations; Female; Humans; Male; Methocarbamol; Middle Aged | 1984 |
Caffeine as an analgesic adjuvant.
Topics: Acetaminophen; Adjuvants, Pharmaceutic; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Headache; Humans; Pain; Pain, Postoperative; Pregnancy; Salicylamides; Tooth Extraction | 1984 |
Distalgesic; safety and efficacy. Efficacy: UK experience.
Topics: Acetaminophen; Apazone; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Drug Combinations; Humans; Pain; United Kingdom | 1984 |
A double-blind randomized study of an aspirin/caffeine combination versus acetaminophen/aspirin combination versus acetaminophen versus placebo in patients with moderate to severe post-partum pain.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Drug Evaluation; Drug Synergism; Female; Humans; Pain; Placebos; Pregnancy; Puerperal Disorders; Random Allocation | 1984 |
[Analgesic, antipyretic and anti-rheumatic activity of 2 preparations evaluated in a multicenter clinical trial].
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Child; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Female; Fever; Humans; Infant; Joint Diseases; Male; Middle Aged; Pain; Rheumatic Diseases; Sulfadimethoxine; Tripelennamine | 1982 |
Effect of caffeine on acetaminophen analgesia.
Topics: Acetaminophen; Analgesia; Analysis of Variance; Caffeine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Female; Humans; Pain, Postoperative | 1983 |
Paracetamol absorption from Paramax, Panadol and Solpadeine.
Topics: Acetaminophen; Administration, Oral; Adult; Caffeine; Codeine; Drug Combinations; Humans; Male; Metoclopramide | 1983 |
The effect of caffeine on the pharmacokinetics of acetaminophen in man.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Coffee; Cross-Over Studies; Drug Combinations; Drug Synergism; Half-Life; Humans; Male | 1995 |
Caffeine as an analgesic adjuvant in tension headache.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Humans; Male; Middle Aged; Tension-Type Headache | 1994 |
[Influence of caffeine on toxicity and pharmacokinetics of paracetamol].
Topics: Acetaminophen; Adult; Alkaline Phosphatase; Animals; Caffeine; Cross-Over Studies; Cytochrome P-450 Enzyme System; Drug Interactions; Glutathione; Humans; Lethal Dose 50; Liver; Male; Mice; Middle Aged; Nonlinear Dynamics; Transaminases | 1995 |
[Analgesic effect and clinical tolerability of the combination of paracetamol 500 mg and caffeine 50 mg versus paracetamol 400 mg and dextropropoxyphene 30 mg in back pain].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Back Pain; Caffeine; Central Nervous System Stimulants; Dextropropoxyphene; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Osteoarthritis; Prospective Studies | 1996 |
It may be the caffeine in Extra Strength Excedrin that is effective for migraine.
Topics: Acetaminophen; Adjuvants, Pharmaceutic; Analgesics; Aspirin; Caffeine; Dose-Response Relationship, Drug; Drug Approval; Drug Combinations; Half-Life; Humans; Migraine Disorders | 1997 |
Efficacy and safety of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain: three double-blind, randomized, placebo-controlled trials.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Migraine Disorders; Pain Measurement; Severity of Illness Index; Treatment Outcome | 1998 |
[The experience with solpadeine -- a new analgesic].
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Caffeine; Codeine; Drug Combinations; Fever; Humans; Middle Aged | 1997 |
Treatment of menstruation-associated migraine with the nonprescription combination of acetaminophen, aspirin, and caffeine: results from three randomized, placebo-controlled studies.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Drug Therapy, Combination; Female; Humans; Menstruation; Middle Aged; Migraine Disorders; Retrospective Studies | 1999 |
Treatment of severe, disabling migraine attacks in an over-the-counter population of migraine sufferers: results from three randomized, placebo-controlled studies of the combination of acetaminophen, aspirin, and caffeine.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Drug Utilization; Female; Humans; Hyperacusis; Male; Middle Aged; Migraine Disorders; Nausea; Nonprescription Drugs; Photophobia; Severity of Illness Index | 1999 |
Novel method to assess gastric emptying in humans: the Pellet Gastric Emptying Test.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Area Under Curve; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Drug Implants; Fasting; Female; Food-Drug Interactions; Gastric Emptying; Humans; Male; Reproducibility of Results; Tablets, Enteric-Coated | 2001 |
Evaluation of the efficacy of a combined formulation (Grippostad-C) in the therapy of symptoms of common cold: a randomized, double-blind, multicenter trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Ascorbic Acid; Caffeine; Chlorpheniramine; Common Cold; Double-Blind Method; Drug Combinations; Histamine H1 Antagonists; Humans; Middle Aged; Phosphodiesterase Inhibitors; Prospective Studies; Treatment Outcome | 2003 |
Oral multidose caffeine-paracetamol combination is not effective for the prophylaxis of postdural puncture headache.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, Spinal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Dura Mater; Female; Headache; Hemodynamics; Humans; Lower Extremity; Male; Middle Aged; Postoperative Complications; Prospective Studies; Spinal Puncture | 2005 |
Eletriptan treatment of migraine in patients switching from barbiturate-containing analgesics: results from a multiple-attack study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Barbiturates; Caffeine; Drug Combinations; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Patient Satisfaction; Pyrrolidines; Quality of Life; Serotonin Receptor Agonists; Treatment Outcome; Tryptamines | 2005 |
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Chi-Square Distribution; Double-Blind Method; Drug Combinations; Dyspepsia; Female; Humans; Male; Migraine Disorders; Nausea; Nonprescription Drugs; Prospective Studies; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome | 2005 |
The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group st
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Synergism; Germany; Humans; Migraine Disorders; Pain Measurement; Placebo Effect; Prognosis; Severity of Illness Index; Tension-Type Headache; Treatment Outcome | 2005 |
Acetaminophen, aspirin, and caffeine in combination versus ibuprofen for acute migraine: results from a multicenter, double-blind, randomized, parallel-group, single-dose, placebo-controlled study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Migraine Disorders | 2006 |
Efficacy of a paracetamol and caffeine combination in the treatment of the key symptoms of primary dysmenorrhoea.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Dysmenorrhea; Female; Humans; Placebos; Treatment Outcome | 2007 |
Caffeine accelerates absorption and enhances the analgesic effect of acetaminophen.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Area Under Curve; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Drug Synergism; Female; Humans; Intestinal Absorption; Male; Middle Aged; Pain; Solubility | 2007 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Central Nervous System Stimulants; Codeine; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Prospective Studies; Treatment Outcome | 2008 |
Tolerability and efficacy of a combination of paracetamol and caffeine in the treatment of tension-type headache: a randomised, double-blind, double-dummy, cross-over study versus placebo and naproxen sodium.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Italy; Male; Middle Aged; Naproxen; Pain Measurement; Pain Threshold; Retrospective Studies; Tension-Type Headache; Young Adult | 2008 |
Headache classification by history has only limited predictive value for headache episodes treated in controlled trials with OTC analgesics.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Nonprescription Drugs; Surveys and Questionnaires; Tension-Type Headache; Young Adult | 2009 |
OTC analgesics in headache treatment: open-label phase vs randomized double-blind phase of a large clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Combinations; Female; Headache Disorders; Humans; Male; Middle Aged; Nonprescription Drugs; Pain Measurement; Phosphodiesterase Inhibitors; Reproducibility of Results; Treatment Outcome; Young Adult | 2009 |
The efficacy of acetaminophen-caffeine compared to Ibuprofen in the control of postoperative pain after periodontal surgery: a crossover pilot study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Chronic Periodontitis; Cross-Over Studies; Debridement; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Periodontal Attachment Loss; Periodontal Diseases; Periodontal Pocket; Pilot Projects; Prospective Studies; Subgingival Curettage; Surgical Flaps; Young Adult | 2009 |
A comparison of intra-articular magnesium and/or morphine with bupivacaine for postoperative analgesia after arthroscopic knee surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anesthetics, Local; Arthroscopy; Bupivacaine; Caffeine; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Injections, Intra-Articular; Magnesium Sulfate; Male; Morphine; Pain Measurement; Pain, Postoperative | 2009 |
[Treating pain after dental surgery: a randomised, controlled, double-blind trial to assess a new formulation of paracetamol, opium powder and caffeine versus tramadol or placebo].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Caffeine; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Male; Molar, Third; Opium; Pain Measurement; Pain, Postoperative; Placebos; Safety; Tooth Extraction; Tooth, Impacted; Tramadol; Treatment Outcome; Young Adult | 2010 |
Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Pain Measurement; Pain, Postoperative; Placebos; Pulpectomy; Pulpitis; Root Canal Preparation; Tramadol; Young Adult | 2012 |
The efficacy and tolerability of a fixed combination of acetylsalicylic acid, paracetamol, and caffeine in patients with severe headache: a post-hoc subgroup analysis from a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel g
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Migraine Disorders; Phosphodiesterase Inhibitors; Placebos; ROC Curve; Severity of Illness Index; Tension-Type Headache; Treatment Outcome; Young Adult | 2011 |
Efficacy and tolerability of combined dipyrone, isometheptene and caffeine in the treatment of mild-to-moderate primary headache episodes.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia; Analgesics; Caffeine; Cross-Over Studies; Dipyrone; Double-Blind Method; Drug Combinations; Female; Headache Disorders, Primary; Humans; Male; Methylamines; Middle Aged; Pain Measurement; Prospective Studies; Treatment Outcome | 2012 |
Pain measurement: Visual Analogue Scale (VAS) and Verbal Rating Scale (VRS) in clinical trials with OTC analgesics in headache.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Area Under Curve; Aspirin; Caffeine; Drug Combinations; Female; Headache; Humans; Male; Middle Aged; Pain Measurement; Reproducibility of Results; ROC Curve; Young Adult | 2012 |
A randomized, controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine (Tylenol 3) after outpatient breast surgery.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Breast Neoplasms; Caffeine; Central Nervous System Stimulants; Codeine; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ibuprofen; Middle Aged; Narcotics; Neoplasm Staging; Pain, Postoperative; Postoperative Complications; Prognosis; Prospective Studies; Tertiary Care Centers | 2012 |
Comparison of tolerability and efficacy of a combination of paracetamol + caffeine and sumatriptan in the treatment of migraine attack: a randomized, double-blind, double-dummy, cross-over study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Caffeine; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Migraine Disorders; Pain Measurement; Sumatriptan; Treatment Outcome; Vasoconstrictor Agents | 2012 |
Efficacy, end points and eventualities: sumatriptan/naproxen versus butalbital/paracetamol/caffeine in the treatment of migraine.
Topics: Acetaminophen; Barbiturates; Caffeine; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Endpoint Determination; Humans; Migraine Disorders; Naproxen; Severity of Illness Index; Sumatriptan; Treatment Outcome | 2012 |
Results of a multicenter, double-blind, randomized, parallel-group, placebo-controlled, single-dose study comparing the fixed combination of acetaminophen, acetylsalicylic acid, and caffeine with ibuprofen for acute treatment of patients with severe migra
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Migraine Disorders | 2014 |
Analgesia evaluation of 2 NSAID drugs as adjuvant in management of chronic temporomandibular disorders.
Topics: Acetaminophen; Adult; Aged; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Carisoprodol; Chronic Pain; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pain Management; Pain Measurement; Temporomandibular Joint Disorders | 2015 |
Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus.
Topics: Acetaminophen; Adult; Aged; Analgesics; Arabs; Biological Availability; Caffeine; Female; Hepatitis C; Humans; Liver Diseases; Male; Middle Aged; Saliva | 2016 |
Bioequivalence and Pharmacokinetic Evaluation Study of Acetaminophen vs. Acetaminophen Plus Caffeine Tablets in Healthy Mexican Volunteers.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Caffeine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Healthy Volunteers; Humans; Male; Mexico; Middle Aged; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency; Young Adult | 2016 |
Pharmacokinetics in Morbid Obesity: Influence of Two Bariatric Surgery Techniques on Paracetamol and Caffeine Metabolism.
Topics: Acetaminophen; Adolescent; Adult; Bariatric Surgery; Biomarkers; Caffeine; Female; Gastrectomy; Gastric Bypass; Humans; Inactivation, Metabolic; Male; Middle Aged; Obesity, Morbid; Weight Loss; Young Adult | 2017 |
Effect of Ginger and Novafen on menstrual pain: A cross-over trial.
Topics: Acetaminophen; Adolescent; Adult; Caffeine; Cross-Over Studies; Drug Combinations; Dysmenorrhea; Female; Humans; Ibuprofen; Iran; Plant Preparations; Statistics, Nonparametric; Visual Analog Scale; Young Adult; Zingiber officinale | 2018 |
No additive effect of acetaminophen when co-ingested with caffeine on cycling performance in well-trained young men.
Topics: Acetaminophen; Caffeine; Double-Blind Method; Glycogen; Humans; Male; Muscle, Skeletal; Performance-Enhancing Substances; Phosphocreatine | 2021 |
The efficacy of low-level laser therapy versus paracetamol-caffeine in controlling orthodontic separation pain and changes in the oral-health-related quality of life in Class I malocclusions: A 3-arm, randomized, placebo-controlled clinical trial.
Topics: Acetaminophen; Caffeine; Female; Humans; Low-Level Light Therapy; Male; Malocclusion, Angle Class I; Pain; Pain Measurement; Quality of Life | 2022 |
Occipital Nerve Block Compared With Acetaminophen and Caffeine for Headache Treatment in Pregnancy: A Randomized Controlled Trial.
Topics: Acetaminophen; Anesthetics, Local; Caffeine; Female; Headache; Humans; Infant, Newborn; Nerve Block; Pregnancy; Premature Birth; Treatment Outcome | 2023 |
416 other study(ies) available for caffeine and acetaminophen
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogPoct: a tool for lipophilicity determination in drug discovery.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Determination of log D via automated microfluidic liquid-liquid extraction.
Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data.
Topics: Humans; Lipids; Membranes, Artificial; Permeability; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrazoles; Pyrimidines | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies.
Topics: Alkaloids; Benzodioxoles; Caco-2 Cells; Cell Differentiation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Humans; Ligands; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines | 2021 |
Gastric erosions induced by analgesic drug mixtures in the rat.
Topics: Acetaminophen; Animals; Aspirin; Caffeine; Drug Combinations; Female; Lethal Dose 50; Phenacetin; Rats; Rats, Inbred Strains; Stomach Ulcer; Time Factors | 1978 |
Effects of phenacetin, paracetamol and caffeine on the erosive activity of acetylsalicylic acid in the rat stomach: dose-response relationships, time course of erosion development and effects on acid secretion.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Female; Gastric Juice; Gastric Mucosa; Male; Phenacetin; Rats; Sex Factors; Time Factors | 1979 |
[The antipyretic effect of Lonarid N in children].
Topics: Acetaminophen; Amobarbital; Caffeine; Child; Child, Preschool; Codeine; Drug Combinations; Drug Evaluation; Fever; Humans; Infant; Suppositories | 1979 |
[Contribution to the study of paracetamol-theophylline and paracetamol-caffeine associations (author's transl)].
Topics: Acetaminophen; Caffeine; Chemical Phenomena; Chemistry; Chemistry, Physical; Theophylline | 1979 |
Liquid chromatographic analysis of analgesics on amberlite XAD-7.
Topics: Acetaminophen; Acrylic Resins; Analgesics; Aspirin; Caffeine; Chromatography, Liquid; Drug Combinations; Phenacetin; Polystyrenes; Salicylamides; Salicylates; Tablets | 1978 |
Augmentation of human blood acetylsalicylate concentrations by the simultaneous administration of acetaminophen with aspirin.
Topics: Acetaminophen; Aspirin; Caffeine; Drug Combinations; Drug Interactions; Humans; Salicylates; Time Factors | 1977 |
[Dualwavelength in situ determination using zigzag scan (author's transl)].
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, Thin Layer; Phenacetin | 1976 |
Para-seltzer.
Topics: Acetaminophen; Caffeine; Drug Combinations; Humans; Tablets | 1976 |
Diseases causing end-stage renal failure in New South Wales.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Australia; Caffeine; Codeine; Cystoscopy; Female; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Phenacetin; Polycystic Kidney Diseases; Pyelonephritis; Renal Dialysis; Salicylamides; Salicylates; Transplantation, Homologous; Urography; Vesico-Ureteral Reflux | 1975 |
G6PD hillbrow: a new variant of glucose-6-phosphate dehydrogenase associated with drug-induced haemolytic anaemia.
Topics: Acetaminophen; Adult; Anemia, Hemolytic; Caffeine; Carisoprodol; Chlormezanone; Diclofenac; Drug Combinations; Erythrocyte Aging; Erythrocytes; Genetic Variation; Glucosephosphate Dehydrogenase; Humans; Male | 1975 |
The induction of renal papillary necrosis in Gunn rats by analgesics and analgesic mixtures.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Caffeine; Female; Heterozygote; Homozygote; Kidney Papillary Necrosis; Male; Phenacetin; Rats; Rats, Inbred Strains | 1975 |
Editorial: The treatment of acute migraine attacks.
Topics: Acetaminophen; Acute Disease; Antiemetics; Aspirin; Caffeine; Ergotamine; Humans; Hypnotics and Sedatives; Migraine Disorders | 1976 |
[Zero-crossing derivative spectrophotometry for the determination of three components in paracetamol compound tablets].
Topics: Acetaminophen; Aspirin; Caffeine; Drug Combinations; Spectrophotometry; Tablets | 1992 |
Pharmacokinetic/pharmacodynamic analysis of the interaction between acetaminophen and caffeine.
Topics: Acetaminophen; Administration, Oral; Animals; Caffeine; Chromatography, High Pressure Liquid; Drug Synergism; Female; Pain; Rats; Rats, Inbred Strains | 1992 |
Caffeine reduces the hepatotoxicity of paracetamol in mice.
Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Bilirubin; Caffeine; Glutathione; Liver; Male; Mice; Mice, Inbred BALB C | 1992 |
Effects of caffeine on paracetamol activation in rat and mouse liver microsomes.
Topics: Acetaminophen; Animals; Caffeine; Inactivation, Metabolic; Male; Mice; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains | 1992 |
Rhabdomyolysis after suicidal ingestion of an overdose of caffeine, acetaminophen and phenazone as a fixed-dose combination (Spalt N).
Topics: Acetaminophen; Adult; Antipyrine; Caffeine; Creatine Kinase; Drug Combinations; Drug Overdose; Humans; Male; Myoglobin; Rhabdomyolysis; Suicide, Attempted; Tablets | 1991 |
Comparison of HPLC and derivative spectrophotometric methods for the determination of paracetamol and caffeine in tablets.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Quality Control; Spectrophotometry, Ultraviolet; Tablets | 1991 |
High performance liquid chromatographic analysis of a multicomponent product using a silica stationary phase and an aqueous-organic mobile phase.
Topics: Acetaminophen; Barbiturates; Caffeine; Chromatography, High Pressure Liquid | 1991 |
[Lobak--a case of disinformation?].
Topics: Acetaminophen; Analgesics; Caffeine; Carisoprodol; Chlormezanone; Diclofenac; Drug Combinations; Drug Information Services; Humans; Sweden | 1991 |
Determination of the optimal analgesia-potentiating dose of caffeine and a study of its effect on the pharmacokinetics of aspirin in mice.
Topics: Acetaminophen; Analgesia; Animals; Aspirin; Caffeine; Dipyrone; Dose-Response Relationship, Drug; Drug Synergism; Female; Half-Life; Male; Mice | 1991 |
A possible case of drug-induced familial pemphigus.
Topics: Acetaminophen; Caffeine; Chlorpheniramine; Common Cold; Drug Combinations; Female; Humans; Middle Aged; Pemphigus; Phenylephrine; Risk Factors | 1990 |
Drug abuse and headache.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Ergot Alkaloids; Headache; Humans; Nonprescription Drugs; Self Medication; Substance-Related Disorders | 1991 |
Determination of the components of analgesic mixtures using high-performance thin-layer chromatography.
Topics: Acetaminophen; Analgesics; Antipyrine; Ascorbic Acid; Caffeine; Chromatography, High Pressure Liquid; Phenacetin; Phenylephrine | 1990 |
Effect of methylxanthines on acetaminophen hepatotoxicity in various induction states.
Topics: Acetaminophen; Alanine Transaminase; Animals; Benzoquinones; Body Temperature; Caffeine; Glutathione; Imines; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1990 |
Separation and determination of the ingredients of a cold medicine by micellar electrokinetic chromatography with bile salts.
Topics: Acetaminophen; Bile Acids and Salts; Caffeine; Chlorpheniramine; Chromatography; Common Cold; Hydrogen-Ion Concentration; Salicylamides; Sodium Dodecyl Sulfate | 1990 |
Screening of solid commercial pharmaceuticals using ion mobility spectrometry.
Topics: Acetaminophen; Analgesics; Aspirin; Brompheniramine; Caffeine; Chlorpheniramine; Ephedrine; Mass Spectrometry; Nonprescription Drugs; Phenylpropanolamine; Spectrum Analysis | 1990 |
Simultaneous determination of propyphenazone, paracetamol and caffeine in blood by high-performance liquid chromatography.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Rats | 1989 |
[Prolonged mydriasis caused by Lamaline].
Topics: Acetaminophen; Belladonna Alkaloids; Caffeine; Humans; Josamycin; Male; Middle Aged; Mydriasis; Opium; Suppositories; Vision Disorders | 1989 |
Simultaneous determination of ascorbic acid, caffeine and paracetamol in drug formulations by differential-pulse voltammetry using a glassy carbon electrode.
Topics: Acetaminophen; Analgesics; Ascorbic Acid; Caffeine; Carbon; Electrodes; Glass; Quality Control | 1989 |
Mechanism of increased hepatotoxicity of acetaminophen by the simultaneous administration of caffeine in the rat.
Topics: Acetaminophen; Animals; Biotransformation; Caffeine; Drug Interactions; Glutathione; In Vitro Techniques; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred Strains | 1989 |
[A quick DC method for simultaneous quantitative determination of paracetamol, caffeine, phenobarbital and propyphenazone in plasma].
Topics: Acetaminophen; Antipyrine; Caffeine; Humans; Phenobarbital | 1989 |
[Densitometric determination of propyphenazone, paracetamol, guaiacol glycerol ether, caffeine and acetylsalicylic acid in analgesic-antipyretic preparations with thin-layer chromatography].
Topics: Acetaminophen; Antipyrine; Aspirin; Caffeine; Chromatography, Thin Layer; Densitometry; Drug Combinations; Guaifenesin | 1989 |
[Analysis of Perdolan tablets using high pressure liquid chromatography].
Topics: Acetaminophen; Analgesics; Aspirin; Bromisovalum; Caffeine; Chromatography, High Pressure Liquid; Codeine; Drug Combinations; Pharmaceutical Vehicles; Urea | 1985 |
Opiates in the restless legs syndrome.
Topics: Acetaminophen; Adult; Aged; Analgesics; Aspirin; Caffeine; Clonazepam; Dextropropoxyphene; Drug Combinations; Female; Humans; Male; Narcotics; Oxycodone; Phenacetin; Restless Legs Syndrome; Temazepam | 1987 |
[Prolonged mydriasis caused by Lamaline].
Topics: Acetaminophen; Belladonna Alkaloids; Caffeine; Drug Combinations; Humans; Male; Middle Aged; Opium; Pupil | 1988 |
Fixed drug eruption due to a drug combination but not to its constituents.
Topics: Acetaminophen; Adult; Analgesics; Caffeine; Carisoprodol; Chlormezanone; Diclofenac; Drug Combinations; Drug Eruptions; Female; Humans | 1985 |
Interaction of caffeine with acetaminophen in mice: schedule dependency of the antagonism by caffeine of acetaminophen hepatotoxicity and the effects of caffeine metabolites, allopurinol, and diethyl ether.
Topics: Acetaminophen; Alanine Transaminase; Allopurinol; Animals; Biotransformation; Caffeine; Ethanol; Ether; Ethyl Ethers; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA | 1988 |
Isocratic liquid chromatographic determination of theophylline, acetaminophen, chloramphenicol, caffeine, anticonvulsants, and barbiturates in serum.
Topics: Acetaminophen; Anticonvulsants; Barbiturates; Caffeine; Chloramphenicol; Chromatography, High Pressure Liquid; Humans; Theophylline | 1988 |
Simultaneous ion-pair and partition liquid chromatography of acetaminophen, theophylline and salicylate with application to 500 toxicologic specimens.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Humans; Salicylates; Spectrophotometry, Ultraviolet; Theophylline | 1988 |
[Significance of the interaction between analgesic-antipyretics and ethanol in forensic medicine investigations].
Topics: Accidents, Traffic; Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Codeine; Drug Combinations; Drug Interactions; Ethanol; Forensic Medicine; Guaifenesin; Humans; Male; Middle Aged; Phenobarbital; Psychomotor Performance | 1987 |
Effects of caffeine on biotransformation and elimination kinetics of acetaminophen in mice.
Topics: Acetaminophen; Animals; Biotransformation; Caffeine; Drug Interactions; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA | 1987 |
Determination of aspirin by pre-column transacetylation reaction of 3-aminophenol and reversed-phase high-performance liquid chromatography: simultaneous determination of aspirin, acetaminophen, and caffeine.
Topics: Acetaminophen; Acetylation; Aminophenols; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations | 1987 |
Effects of caffeine on acetaminophen-induced hepatotoxicity and cadmium redistribution in mice.
Topics: Acetaminophen; Animals; Cadmium; Caffeine; Drug Administration Schedule; Drug Synergism; Kidney; Liver; Male; Mice; Microsomes, Liver | 1986 |
Deoxyglucose-autoradiography of the hypothalamus after food deprivation in the mouse.
Topics: Acetaminophen; Animals; Autoradiography; Caffeine; Deoxy Sugars; Deoxyglucose; Drug Combinations; Food Deprivation; Guaifenesin; Hypothalamus; Male; Mice; Mice, Inbred Strains | 1986 |
Bioavailability of paracetamol after oral administration to healthy volunteers. Influence of caffeine on rate and extent of absorption.
Topics: Acetaminophen; Biological Availability; Caffeine; Drug Combinations; Humans; Intestinal Absorption; Male; Solubility | 1986 |
[Quantitative analysis of a three-component mixture--compound tablets of acetaminophen using signal multiplier spectrophotometry].
Topics: Acetaminophen; Aspirin; Caffeine; Drug Combinations; Microcomputers; Spectrophotometry, Ultraviolet; Tablets | 1986 |
Acetaminophen-induced hepatotoxicity: antagonistic action of caffeine in mice.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Binding Sites; Cadmium; Caffeine; Chemical and Drug Induced Liver Injury; Fasting; Glutathione; Kidney; Male; Mice | 1987 |
Impact of over the counter availability of non-steroidal anti-inflammatory drugs.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Caffeine; Codeine; Humans; Ibuprofen; Nonprescription Drugs; United States | 1985 |
Migraine--treatment of acute attack.
Topics: Acetaminophen; Acute Disease; Aspirin; Caffeine; Ergotamine; Ergotamines; Humans; Metoclopramide; Migraine Disorders; Sleep; Time Factors | 1985 |
Increased hepatotoxicity of acetaminophen by concomitant administration of caffeine in the rat.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeine; Chemical and Drug Induced Liver Injury; Drug Interactions; Liver Diseases; Male; Necrosis; Rats; Rats, Inbred Strains | 1985 |
High-pressure liquid chromatographic analysis of paracetamol, caffeine and acetylsalicylic acid in tablets. Salicylic acid quantitation.
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Salicylates; Salicylic Acid; Tablets | 1985 |
[Evaluation of the analgesic activity of a preconstituted combination of acetylsalicylic acid, paracetamol and caffeine].
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Caffeine; Drug Combinations; Drug Evaluation; Female; Humans; Middle Aged; Pain | 1985 |
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium | 1973 |
[Comparative study on quantitative determination of mixtures of analgesics. 1. Studies on selectivity of volumetric analysis procedures].
Topics: Acetaminophen; Aminopyrine; Analgesics; Ascorbic Acid; Aspirin; Barbiturates; Caffeine; Chlorpromazine; Codeine; Conductometry; Electrochemistry; Meprobamate; Mesylates; Methods; Papaverine; Phenacetin; Phenobarbital; Phenylbutazone; Potentiometry; Quinine; Salicylamides; Salicylates; Theobromine | 1974 |
The nephrotoxicity of analgesics.
Topics: Acetaminophen; Aspirin; Caffeine; Erythrocytes; Female; Humans; Kidney; Kidney Tubules; Leukocytes; Male; Nephritis; Phenacetin | 1966 |
A comparison of propoxyphene HCl (Darvon) and an analgesic mixture (Percogesic) in pain relief after gingivectomy.
Topics: Acetaminophen; Adult; Analgesics; Atropine; Caffeine; Dextropropoxyphene; Female; Gingivectomy; Histamine H1 Antagonists; Humans; Male; Middle Aged; Pain | 1967 |
[Clinical study of a new antalgic: Propofan].
Topics: Acetaminophen; Adult; Aged; Analgesics; Aspirin; Caffeine; Dextropropoxyphene; Female; Headache; Histamine H1 Antagonists; Humans; Male; Middle Aged; Pain; Rheumatic Diseases; Vascular Diseases | 1972 |
Quantitative analysis of a multicomponent analgesic product containing butalbital, using high speed reverse-phase liquid chromatography.
Topics: Acetaminophen; Allyl Compounds; Analgesics; Aspirin; Barbiturates; Caffeine; Chromatography; Drug Combinations; Phenacetin; Tablets | 1974 |
[Propofan as an antalgic in general surgery. Apropos of 50 cases].
Topics: Acetaminophen; Analgesics; Aspirin; Bone Diseases; Caffeine; Chlorpheniramine; Dextropropoxyphene; Drug Combinations; Fractures, Bone; Humans; Lidocaine; Peritoneal Diseases; Postoperative Care; Suppositories; Tablets; Wounds and Injuries | 1972 |
The short-term effects of analgesics on the kidney with special reference to acetylsalicylic acid.
Topics: Acetaminophen; Acute Kidney Injury; Administration, Oral; Animals; Aspirin; Caffeine; Dose-Response Relationship, Drug; Drug Combinations; Female; Kidney Cortex; Kidney Tubules; Male; Nephrons; Phenacetin; Rats; Regeneration; Time Factors | 1973 |
Separation of morphine alkaloids, heroin, methadone and other drugs by ion-exchange chromatography.
Topics: Acetaminophen; Aspirin; Autoanalysis; Caffeine; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Heroin; Methadone; Methods; Morphine; Opium; Phenacetin; Solvents | 1973 |
Effects of caffeine on the absorption and analgesic efficacy of paracetamol in rats.
Topics: Acetaminophen; Administration, Oral; Analgesics; Animals; Caffeine; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Inflammation; Intestinal Absorption; Kinetics; Male; Pain; Rats; Time Factors | 1973 |
[Risks in long-term treatment with analgesics].
Topics: Acetaminophen; Analgesics; Antipyrine; Aspirin; Caffeine; Diuresis; Drug Combinations; Humans; Kidney Diseases; Mental Disorders; Phenacetin; Substance-Related Disorders | 1973 |
Aspirin and the kidney. New Zealand Rheumatism Association Study.
Topics: Acetaminophen; Adult; Arthritis, Rheumatoid; Aspirin; Caffeine; Codeine; Drug Synergism; Female; Humans; Kidney Diseases; Male; Middle Aged; New Zealand; Osteoarthritis; Phenacetin; Phenylbutazone; Salicylates; Urinary Tract Infections | 1974 |
General and renal toxicity of phenacetin, paracetamol and some anti-mitotic agents in the rat.
Topics: Acetaminophen; Anemia, Macrocytic; Anilides; Animals; Blood; Blood Glucose; Body Weight; Caffeine; Depression, Chemical; Diuresis; Feeding Behavior; Glomerular Filtration Rate; Growth; Kidney; Male; Mercaptopurine; Methemoglobinemia; Phenacetin; Rats; Urea; Urine | 1972 |
[Practical experience with Neuramag sine].
Topics: Acetaminophen; Adult; Aged; Aspirin; Caffeine; Chemical Phenomena; Chemistry; Drug Combinations; Female; Humans; Male; Middle Aged; Pain | 1972 |
The effect of acetylsalicylic acid, caffeine, and codeine on the excretion of phenacetin metabolites.
Topics: Acetaminophen; Aniline Compounds; Aspirin; Caffeine; Chromatography, Thin Layer; Codeine; Creatinine; Ethyl Ethers; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Phenacetin; Time Factors; Tritium | 1972 |
Complexation of acetaminophen with methyl xanthines.
Topics: Acetaminophen; Caffeine; Calorimetry; Chemistry, Pharmaceutical; Kinetics; Magnetic Resonance Spectroscopy; Solubility; Spectrophotometry; Spectrum Analysis; Theobromine; Theophylline | 1972 |
100-day LD 50 index of chronic toxicity.
Topics: Acetaminophen; Administration, Oral; Animals; Aspirin; Atropine; Caffeine; DDT; Drug-Related Side Effects and Adverse Reactions; Intubation, Gastrointestinal; Lethal Dose 50; Penicillin G; Phenacetin; Pilocarpine; Rats; Sodium Chloride; Sucrose; Time Factors | 1971 |
Haemoglobinuria in Nigerian children.
Topics: Acetaminophen; Aspirin; Autopsy; Brain; Caffeine; Child; Child, Preschool; Coombs Test; Diagnosis, Differential; Erythrocytes; Female; Genotype; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Hemoglobinuria; Humans; Infant; Kidney; Liver; Malaria; Male; Nigeria; Phenacetin; Quinine; Sex Factors; Spleen; Sulfonamides | 1971 |
GLC analysis of multicomponent suppository formulations.
Topics: Acetaminophen; Amides; Aminopyrine; Aspirin; Benzoates; Caffeine; Chlorpheniramine; Chromatography, Gas; Dextropropoxyphene; Ethylamines; Lidocaine; Malonates; Phenacetin; Sulfadimethoxine; Suppositories | 1971 |
The analysis of aspirin and related compounds by liquid chromatography.
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, Ion Exchange; Computers; Methods; Phenacetin; Salicylamides | 1971 |
Gas-liquid chromatographic assay for salicylamide, acetaminophen, and caffeine mixtures, using on-line, computerized real-time data acquisition.
Topics: Acetaminophen; Caffeine; Chromatography, Gas; Computers; Drug Combinations; Evaluation Studies as Topic; Methods; Online Systems; Salicylamides; Spectrophotometry, Ultraviolet | 1971 |
[Study of a new combination of analgesic substances].
Topics: Acetaminophen; Adult; Caffeine; Female; Humans; Male; Pain; Salicylamides | 1965 |
Analgesic nephropathy. A common form of renal disease in Australia.
Topics: Acetaminophen; Analgesics; Anemia; Animals; Aspirin; Australia; Caffeine; Diagnosis, Differential; Drug and Narcotic Control; Drug Synergism; Drug Utilization; Female; Humans; Kidney Function Tests; Kidney Papillary Necrosis; Nephritis, Interstitial; Phenacetin; Radiography; Substance-Related Disorders; Uremia | 1969 |
Reactions of acetaminophen in pharmaceutical dosage forms: its proposed acetylation by acetylsalicylic acid.
Topics: Acetaminophen; Aspirin; Caffeine; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Codeine; Dosage Forms; Drug Stability; Humidity; Spectrophotometry; Temperature | 1970 |
Fluorometric determination of salicylic acid in aspirin products including noninterfering, interfering, and buffered substances.
Topics: Acetaminophen; Aspirin; Buffers; Caffeine; Fluorometry; Methods; Salicylates; Tablets | 1970 |
Phenacetin nephropathy.
Topics: Acetaminophen; Animals; Aspirin; Caffeine; Humans; Kidney Diseases; Phenacetin; Rats | 1970 |
[Treatment of vascular headaches with a new compound preparation].
Topics: Acetaminophen; Adult; Amobarbital; Analgesics; Caffeine; Codeine; Ergotamine; Female; Headache; Humans; Male; Middle Aged; Tartrates; Vascular Headaches | 1970 |
Determination of acetylsalicylic acid, salicylamide, acetaminophen, and caffeine in tablets or powders by independent methods.
Topics: Acetaminophen; Aspirin; Autoanalysis; Caffeine; Methods; Salicylamides; Spectrophotometry; Tablets | 1968 |
Analgesic abuse: maximal tolerated daily doses of acetylsalicylic acid.
Topics: Acetaminophen; Acids; Analgesics; Animals; Appetite; Aspirin; Brain; Caffeine; Growth; Humans; Phenacetin; Rats; Substance-Related Disorders; Thirst; Water | 1968 |
[Determination of pharmaceutical preparations by gas chromatography. I. Determination of acetaminophen and other components in antipyretic preparations].
Topics: Acetaminophen; Analgesics; Caffeine; Chromatography, Gas | 1968 |
Interactions between pharmaceutical compounds by thermal methods.
Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K | 1969 |
Additive and augmentative synergism between analgesic drugs.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Caffeine; Codeine; Dextropropoxyphene; Drug Synergism; Hydroxyzine; Meprobamate; Mice; Phenacetin | 1965 |
[New combined therapy in influenza and common cold with Theraflu].
Topics: Acetaminophen; Adult; Caffeine; Child; Codeine; Common Cold; Female; Flavonoids; Humans; Influenza, Human; Male; Pyrazoles | 1965 |
Gas-liquid chromatography of submicrogram amounts of drugs. I. Preparation, scope and limitation of columns.
Topics: Acetaminophen; Amphetamine; Caffeine; Chlordiazepoxide; Chromatography, Gas; Cyclizine; Morphine; Phenelzine; Phenylbutazone; Salicylates; Scopolamine; Secobarbital; Trifluoperazine | 1966 |
Cardiovascular lesions in Sprague-Dawley rats induced by long-term treatment with caffeine.
Topics: Acetaminophen; Animals; Antipyrine; Caffeine; Cardiovascular Diseases; Heart; Male; Myocardial Infarction; Myocardium; Necrosis; Phenacetin; Polyarteritis Nodosa; Rats; Rats, Inbred Strains; Splanchnic Circulation | 1981 |
Theophylline, dyphylline, caffeine, acetaminophen, salicylate, acetylsalicylate, procainamide, and N-acetylprocainamide determined in serum with a single liquid-chromatographic assay.
Topics: Acecainide; Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Dyphylline; Humans; Pharmaceutical Preparations; Procainamide; Salicylates; Salicylic Acid; Theophylline | 1982 |
Reduction in caffeine toxicity by acetaminophen.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Acetaminophen; Acoustic Stimulation; Adenosine; Adult; Animals; Brain; Caffeine; Drug Interactions; Female; Humans; Mice; Seizures | 1982 |
Combination analgesics.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Codeine; Dextropropoxyphene; Drug Interactions; Drug Therapy, Combination; Humans; Hydrocodone; Narcotics; Oxycodone; Phenacetin; Primary Health Care; Tranquilizing Agents | 1984 |
Paracetamol absorption from Paramax, Panadol and Solpadeine.
Topics: Absorption; Acetaminophen; Caffeine; Codeine; Drug Combinations; Humans; Metoclopramide | 1983 |
[Quantification of the attenuation of pain sensation through evoked potentials after the application of mild analgesics (author's transl)].
Topics: Acetaminophen; Aspirin; Caffeine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Evoked Potentials; Humans; Sensory Thresholds | 1980 |
Comparison of Syndol and paracetamol in the relief of dental pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Caffeine; Codeine; Double-Blind Method; Doxylamine; Drug Combinations; Drug Evaluation; Female; Humans; Male; Middle Aged; Mouth; Pain, Postoperative; Pyridines; Random Allocation | 1981 |
Post-anaesthetic dental extraction analgesia: a comparison of paracetamol, codeine, caffeine (Solpadeine) and diflunisal (Dolobid).
Topics: Acetaminophen; Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, General; Caffeine; Codeine; Diflunisal; Drug Combinations; Female; Humans; Male; Middle Aged; Pain, Postoperative; Salicylates; Tooth Extraction | 1982 |
Epidemiology of analgesic nephropathy in Belgium.
Topics: Acetaminophen; Analgesics; Antipyrine; Aspirin; Belgium; Caffeine; Drug Combinations; Humans; Kidney Diseases; Phenacetin | 1982 |
Automated analysis of acetaminophen and caffeine in serum using the FAST-LC system: contributions to assay imprecision in procedures based on HPLC with sample pretreatment.
Topics: Acetaminophen; Anticonvulsants; Autoanalysis; Caffeine; Chromatography, High Pressure Liquid; Humans | 1982 |
[Gynecologic-obstetric pain therapy. Use of Lonarid N].
Topics: Acetaminophen; Adolescent; Adult; Amobarbital; Caffeine; Codeine; Drug Combinations; Dysmenorrhea; Endometritis; Episiotomy; Female; Humans; Middle Aged; Pain; Parametritis; Pelvic Inflammatory Disease; Premenstrual Syndrome | 1980 |
[A comparative pharmacokinetic study for tablet and suppository formulations of a combination product of caffeine, ethaverine, propyphenazone, paracetamol and phenobarbital (author's transl)].
Topics: Acetaminophen; Adult; Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Kinetics; Male; Papaverine; Phenobarbital; Rectum; Suppositories; Tablets | 1981 |
Analgesic drugs in breast milk and plasma.
Topics: Acetaminophen; Adult; Analgesics; Caffeine; Codeine; Female; Humans; Kinetics; Milk, Human; Morphine; Phenacetin; Salicylates | 1981 |
Spectrofluorometric determination of acetylsalicylic acid, salicylamide, and salicyclic acid as an impurity in pharmaceutical preparations.
Topics: Acetaminophen; Aspirin; Buffers; Caffeine; Drug Combinations; Drug Contamination; Salicylamides; Salicylates; Salicylic Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1981 |
Carcinogenicity of analgesics: long-term treatment of Sprague-Dawley rats with phenacetin, phenazone, caffeine and paracetamol (acetamidophen).
Topics: Acetaminophen; Adenocarcinoma; Analgesics; Animals; Antipyrine; Caffeine; Carcinogens; Carcinoma, Squamous Cell; Kidney; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Phenacetin; Rats; Rats, Inbred Strains; Sarcoma; Time Factors; Urinary Tract; Urologic Diseases | 1981 |
Simultaneous quantitation of acetaminophen, aspirin, caffeine, codeine phosphate, phenacetin, and salicylamide by high-pressure liquid chromatography.
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Codeine; Phenacetin; Salicylamides | 1980 |
Interactions of aspirin with acetaminophen and caffeine in rat stomach: pharmacokinetics of absorption and accumulation in gastric mucosa.
Topics: Acetaminophen; Animals; Aspirin; Caffeine; Chromatography, Gas; Drug Interactions; Gastric Mucosa; Intestinal Absorption; Kinetics; Rats | 1980 |
Analgesic nephropathy induced by common proprietary mixtures.
Topics: Acetaminophen; Analgesics; Animals; Antipyrine; Caffeine; Drug Combinations; Female; Humans; Kidney Papillary Necrosis; Nonprescription Drugs; Phenacetin; Rats; Salicylamides; Substance-Related Disorders | 1980 |
[Analgesic therapy in the orthopedic office. Experiences with Lonarid N].
Topics: Acetaminophen; Amobarbital; Analgesia; Bone Diseases; Caffeine; Codeine; Drug Combinations; Humans | 1980 |
Use of differential kinetic method in assay of acetylsalicylic acid in combination with paracetamol and caffeine.
Topics: Acetaminophen; Aspirin; Caffeine; Drug Combinations; Kinetics; Methods; Tablets | 1980 |
Aspirin and acetaminophen as constituents of analgesic combinations.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Combinations; Humans; Narcotics | 1981 |
Cytochrome P4502E1 inhibition by propylene glycol prevents acetaminophen (paracetamol) hepatotoxicity in mice without cytochrome P4501A2 inhibition.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Liver; Male; Mice; Mice, Inbred Strains; Oxidoreductases, N-Demethylating; Propylene Glycol; Propylene Glycols | 1995 |
Relative potency of two preparations in two-way elimination of heterogeneity designs with multivariate responses.
Topics: Acetaminophen; Analgesia; Analgesics; Biometry; Caffeine; Dentistry; Humans; Mathematics; Models, Statistical; Multivariate Analysis; Pain; Pain Measurement; Randomized Controlled Trials as Topic; Regression Analysis; Research Design | 1995 |
Selective effects of a bacterial infection (Actinobacillus pleuropneumoniae) on the hepatic clearances of caffeine, antipyrine, paracetamol, and indocyanine green in the pig.
Topics: Acetaminophen; Actinobacillus Infections; Actinobacillus pleuropneumoniae; Animals; Antipyrine; Caffeine; Creatinine; Indocyanine Green; Liver; Male; Swine | 1995 |
Rapid high-performance liquid chromatographic determination of vancomycin in human plasma.
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Humans; Quality Control; Sensitivity and Specificity; Vancomycin | 1995 |
Microdialysis sampling coupled on-line to fast microbore liquid chromatography.
Topics: Acetaminophen; Animals; Caffeine; Chromatography, High Pressure Liquid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Theobromine; Theophylline | 1995 |
The influence of environmental and genetic factors on CYP2D6, CYP1A2 and UDP-glucuronosyltransferases in man using sparteine, caffeine, and paracetamol as probes.
Topics: Acetaminophen; Adolescent; Adult; Caffeine; Coffee; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Female; Genotype; Glucuronates; Glucuronosyltransferase; Humans; Male; Middle Aged; Mixed Function Oxygenases; Nicotiana; Oxidation-Reduction; Oxidoreductases; Phenotype; Plants, Toxic; Random Allocation; Sex Factors; Smoking; Sparteine | 1994 |
Characterization of the analgesic effect of paracetamol and caffeine combinations in the pain-induced functional impairment model in the rat.
Topics: Acetaminophen; Administration, Oral; Animals; Caffeine; Drug Combinations; Drug Synergism; Female; Hindlimb; Pain; Pain Measurement; Rats; Rats, Wistar; Uric Acid | 1993 |
Hepatic glutathione and lipid peroxidation in rats treated with theophylline. Effect of dose and combination with caffeine and acetaminophen.
Topics: Acetaminophen; Animals; Caffeine; Dose-Response Relationship, Drug; Glutathione; Lipid Peroxidation; Liver; Male; Rats; Theophylline | 1994 |
Mixed ion pair liquid chromatography method for the simultaneous assay of ascorbic acid, caffeine, chlorpheniramine maleate, dextromethorphan HBr monohydrate and paracetamol in Frenadol sachets.
Topics: Acetaminophen; Alkanesulfonic Acids; Ascorbic Acid; Caffeine; Chlorpheniramine; Chromatography, High Pressure Liquid; Dextromethorphan; Dosage Forms; Nonprescription Drugs; Quality Control; Quaternary Ammonium Compounds; Reference Standards; Reproducibility of Results | 1994 |
Impurities, adulterants and diluents of illicit heroin. Changes during a 12-year period.
Topics: Acetaminophen; Caffeine; Carbohydrates; Denmark; Drug Contamination; Heroin; Hydrogen-Ion Concentration; Illicit Drugs; Lactose; Morphine; Noscapine; Papaverine; Phenobarbital; Procaine | 1994 |
[A fatal case due to intoxication with seven drugs detected by GC-MS and TDx methods].
Topics: Acetaminophen; Adult; Bromisovalum; Caffeine; Drug Overdose; Female; Fluorescent Antibody Technique; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; Salicylamides; Suicide; Urea | 1993 |
Acetaminophen-induced eosinophilic pneumonia.
Topics: Acetaminophen; Bromisovalum; Caffeine; Drug Combinations; Drug Eruptions; Eosinophilia; Humans; Lymphocyte Activation; Male; Middle Aged; Pulmonary Eosinophilia | 1993 |
Interaction of caffeine with acetaminophen. 1. Correlation of the effect of caffeine on acetaminophen hepatotoxicity and acetaminophen bioactivation following treatment of mice with various cytochrome P450 inducing agents.
Topics: Acetaminophen; Acetone; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzoquinones; beta-Naphthoflavone; Biotransformation; Caffeine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Activation; Female; Imines; Isoenzymes; Kinetics; Liver Diseases; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital | 1993 |
Effects of caffeine and theophylline on acetaminophen pharmacokinetics: P450 inhibition and activation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzoquinones; Caffeine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Activation; Glutathione; Imines; Male; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Theophylline | 1996 |
[Determination of paracetmol caffeine and ephedrine hydrochloride in likeshu capsules].
Topics: Acetaminophen; Anti-Infective Agents; Caffeine; Capsules; Drug Combinations; Ephedrine; Spectrophotometry, Ultraviolet | 1995 |
Effect of acetylsalicylic acid, paracetamol, caffeine and a combination of these substances on the renal prostaglandin E2, 6-keto-prostaglandin F1 alpha, water, creatinine and electrolyte excretion of the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Body Water; Caffeine; Central Nervous System Stimulants; Creatinine; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electrolytes; Female; Kidney; Rats; Rats, Inbred Strains | 1996 |
Effects of acetylsalicylic acid, paracetamol and caffeine and a combination of these substances on kidney glutathione levels.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Combinations; Glutathione; Kidney; Liver; Male; Mice; Rats; Rats, Inbred Strains; Species Specificity | 1996 |
Simultaneous assay of phenylpropanolamine hydrochloride, caffeine, paracetamol, glycerylguaiacolate and chlorpheniramine maleate in Silabat tablet using HPLC with diode array detection.
Topics: Acetaminophen; Caffeine; Chlorpheniramine; Chromatography, High Pressure Liquid; Drug Combinations; Guaifenesin; Indicators and Reagents; Phenylpropanolamine; Tablets | 1995 |
Studies on the chronic oral toxicity of an analgesic drug combination consisting of acetylsalicylic acid, paracetamol and caffeine in rats including an electron microscopical evaluation of kidneys.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Blood Cell Count; Body Weight; Caffeine; Central Nervous System Stimulants; Drug Combinations; Enzymes; Female; Kidney Diseases; Male; Microscopy, Electron; Organ Size; Rats; Rats, Wistar | 1996 |
Simultaneous determination of acetaminophen, dipyrone and caffeine in pharmaceutical preparations by the absorbance ratio technique.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Dipyrone; Drug Combinations; Spectrophotometry, Ultraviolet; Tablets | 1996 |
Adulteration by synthetic therapeutic substances of traditional Chinese medicines in Taiwan.
Topics: Acetaminophen; Caffeine; Drug Contamination; Drugs, Chinese Herbal; Indomethacin; Taiwan | 1997 |
Changes in formalin-evoked spinal Fos expression and nociceptive behaviour after oral administration of Bufferin A (aspirin) and L-5409709 (ibuprofen + caffeine + paracetamol).
Topics: Acetaminophen; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Drug Combinations; Formaldehyde; Ibuprofen; Immunohistochemistry; Male; Nociceptors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord | 1997 |
[Nephrotoxicity of analgesic combination preparations].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Humans; Kidney Failure, Chronic; Phenacetin; Risk Factors | 1997 |
[Comment on the contribution: "Usefulness of fixed analgesic combinations exemplified by thomapyrin"].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Humans; Kidney Failure, Chronic; Phenacetin; Risk Factors | 1997 |
[Caffetin in the treatment of neck pain and lumbago-sciatica].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Codeine; Drug Combinations; Drug Evaluation; Humans; Low Back Pain; Neck Pain; Pain Measurement; Sciatica | 1997 |
[Clinical features of daily chronic headache].
Topics: Acetaminophen; Adult; Age of Onset; Analgesics; Benzodiazepines; Caffeine; Chronic Disease; Ergotamine; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Severity of Illness Index | 1997 |
Increased basal expression of hepatic Cyp1a1 and Cyp1a2 genes in inbred mice selected for susceptibility to acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Caffeine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Female; Gene Expression Regulation; Immunoassay; Intubation, Gastrointestinal; Liver; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; RNA, Messenger; Sex Factors | 1997 |
Role of caffeine in combined analgesic drugs from the point of view of experimental pharmacology.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Chemistry; Caffeine; Cattle; Central Nervous System Stimulants; Drug Combinations; Electric Stimulation; Enzymes; In Vitro Techniques; Inflammation; Liver; Mice; Mice, Inbred Strains; Motor Activity; Pain Measurement; Physical Stimulation; Prostaglandins; Rats; Rats, Inbred Strains; Stomach Ulcer | 1997 |
[The efficacy of Solpadeine in patients with primary forms of headache].
Topics: Acetaminophen; Adult; Analgesics; Caffeine; Codeine; Drug Combinations; Drug Evaluation; Female; Humans; Male; Middle Aged; Migraine Disorders; Pain Measurement; Tension-Type Headache | 1997 |
[The use of the preparation Solpadeine in dental practice].
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Codeine; Dipyrone; Drug Combinations; Drug Evaluation; Fever; Humans; Middle Aged; Pain; Tablets | 1997 |
Differences in caffeine 3-demethylation activity among inbred mouse strains: a comparison of hepatic Cyp1a2 gene expression between two inbred strains.
Topics: Acetaminophen; Animals; Caffeine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; DNA, Complementary; Female; Gene Expression Regulation, Enzymologic; Immunoblotting; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Oligonucleotide Probes; Phenotype; RNA, Messenger; Sex Factors; Theophylline | 1997 |
[The treatment of a complex regional pain syndrome].
Topics: Acetaminophen; Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Cerebrovascular Disorders; Codeine; Combined Modality Therapy; Drug Combinations; Evaluation Studies as Topic; Hand Injuries; Humans; Hyperbaric Oxygenation; Leg Injuries; Nerve Compression Syndromes; Pain Measurement; Reflex Sympathetic Dystrophy; Soft Tissue Injuries | 1997 |
Drug marker absorption in relation to pellet size, gastric motility and viscous meals in humans.
Topics: Acetaminophen; Adult; Area Under Curve; Caffeine; Female; Food-Drug Interactions; Gastric Emptying; Humans; Male; Viscosity | 1998 |
Minimizing migraines.
Topics: Acetaminophen; Aspirin; Caffeine; Drug Combinations; Humans; Migraine Disorders; Riboflavin | 1998 |
Analgesic nephropathy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Drug Interactions; Humans; Kidney Diseases; Phenacetin | 1998 |
[On postop strategies in surgically treated forms of ethmoid sinusitis].
Topics: Acetaminophen; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Caffeine; Chronic Disease; Codeine; Drug Combinations; Ethmoid Sinusitis; Humans; Middle Aged; Peptides; Postoperative Care; Thymus Extracts; Treatment Outcome | 1998 |
[Abuse of and dependence on mixed analgesics--clinical aspects and differential diagnostic problems].
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Diagnosis, Differential; Drug Combinations; Humans; Male; Substance-Related Disorders | 1998 |
Solitary rectal ulcer induced by excessive use of analgesic suppositories containing paracetamol, caffeine, and codeine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Caffeine; Codeine; Drug Combinations; Endoscopy; Female; Humans; Middle Aged; Rectal Diseases; Suppositories; Ulcer; Ultrasonography | 1998 |
Limitations of acetaminophen, aspirin, and caffeine in alleviating migraine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Drug Therapy, Combination; Humans; Migraine Disorders; Recurrence; Reproducibility of Results; Severity of Illness Index; Treatment Outcome | 1998 |
Gradient elution capillary electrochromatography and hyphenation with nuclear magnetic resonance.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Chromatography, Liquid; Electrophoresis, Capillary; Magnetic Resonance Spectroscopy; Molecular Structure | 1999 |
Treatment for postdural puncture headache associated with late postpartum eclampsia.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Benzoates; Blood Patch, Epidural; Caffeine; Drug Combinations; Eclampsia; Epilepsy, Tonic-Clonic; Female; Headache; Humans; Pregnancy; Puerperal Disorders; Punctures | 1999 |
Separation of theophylline, caffeine and related drugs by normal-phase capillary electrochromatography.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Dyphylline; Electric Conductivity; Electrophoresis, Capillary; Hydrochlorothiazide; Molecular Structure; Niacin; Phenylbutazone; Theobromine; Theophylline | 1999 |
A comparative study of the ratio spectra derivative spectrophotometry, Vierordt's method and high-performance liquid chromatography applied to the simultaneous analysis of caffeine and paracetamol in tablets.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Spectrophotometry, Ultraviolet; Tablets | 1999 |
Simultaneous determination of paracetamol, caffeine and acetylsalicylic acid by means of a FI ultraviolet pls multioptosensing device.
Topics: Acetaminophen; Aspirin; Caffeine; Electronic Data Processing; Flow Injection Analysis; Hydrogen-Ion Concentration; Least-Squares Analysis; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets | 1999 |
Simultaneous determination of some multicomponent dosage forms by quantitative thin layer chromatography densitometric method.
Topics: Acetaminophen; Caffeine; Chlorzoxazone; Chromatography, Thin Layer; Densitometry; Diflunisal; Dosage Forms; Naproxen; Pharmaceutical Preparations; Solvents; Theophylline | 1999 |
[Clinical evaluation of the efficacy of the paracetamol and caffeine combination in the treatment of tension headache].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Tension-Type Headache; Treatment Outcome | 2000 |
HPLC determination of caffeine in a multicomponent preparation.
Topics: Acetaminophen; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Drug Combinations; Indicators and Reagents; Solutions; Spectrophotometry, Ultraviolet | 2000 |
A case of toxic epidermal necrolysis-type drug eruption induced by oral lysozyme chloride.
Topics: Acetaminophen; Administration, Oral; Adult; Anti-Inflammatory Agents; Betamethasone; Biopsy, Needle; Caffeine; Common Cold; Drug Combinations; Follow-Up Studies; Guaiacol; Humans; Male; Muramidase; Nonprescription Drugs; Stevens-Johnson Syndrome; Urticaria | 2000 |
Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E(2) synthesis in rat microglial cells.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Caffeine; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Isoenzymes; Lipopolysaccharides; Microglia; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 2000 |
"Chap Kaki Tiga" a possible cause of upper gastrointestinal haemorrhage.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Drug Combinations; Gastrointestinal Hemorrhage; Humans; Powders | 1996 |
[Perioperative management of a patient with a history of over-the-counter analgesic abuse for 20 years].
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anesthesia, General; Caffeine; Gastrectomy; Humans; Male; Nonprescription Drugs; Perioperative Care; Salicylamides; Stomach Neoplasms; Substance-Related Disorders | 2000 |
Warning: the excedrin migraine warning label is inadequate to warn consumers of the risk of medication rebound headache.
Topics: Acetaminophen; Adult; Aspirin; Caffeine; Drug Combinations; Drug Labeling; Female; Humans; Migraine Disorders; Risk Factors | 1999 |
Direct toxicity of nonsteroidal antiinflammatory drugs for renal medullary cells.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caffeine; Cell Division; Cell Line; Cyclooxygenase Inhibitors; Drug Interactions; Flow Cytometry; Indomethacin; Kidney Tubules, Collecting; Mice; Microscopy, Electron; Salicylic Acid | 2001 |
[Analysis of paracetamol, caffeine and chlorphenamine maleate in suxiaoshangfeng capsules by capillary gas chromatography].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Caffeine; Capsules; Chlorpheniramine; Chromatography, Gas; Drug Compounding; Drugs, Chinese Herbal | 1998 |
Fluorescence quenching high-performance thin-layer chromatographic analysis utilizing a scientifically operated charge-coupled device detector.
Topics: Acetaminophen; Aspirin; Autoanalysis; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Famotidine; Sensitivity and Specificity; Signal Processing, Computer-Assisted | 2001 |
[Analgesics-induced chronic renal failure in patients on dialysis therapy in Hungary].
Topics: Acetaminophen; Adult; Aged; Amphetamine; Analgesics; Aspirin; Caffeine; Codeine; Female; Humans; Hungary; Kidney Failure, Chronic; Male; Middle Aged; Phenacetin; Prevalence; Renal Dialysis; Tomography, X-Ray Computed | 2001 |
Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline.
Topics: Acetaminophen; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Caffeine; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inhibitory Concentration 50; Kinetics; Magnesium Chloride; Microsomes, Liver; Mixed Function Oxygenases; Models, Chemical; Pentoxifylline; Phenacetin; Protein Binding; Serum Albumin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline; Time Factors; Tromethamine; Xanthines | 2001 |
Derivative ratio spectra-zero crossing spectrophotometry and LC method applied to the quantitative determination of paracetamol, propyphenazone and caffeine in ternary mixtures.
Topics: Acetaminophen; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Indicators and Reagents; Solutions; Spectrophotometry, Ultraviolet; Tablets | 2001 |
LC method for the analysis of paracetamol, caffeine and codeine phosphate in pharmaceutical preparations.
Topics: Acetaminophen; Caffeine; Calibration; Chromatography, High Pressure Liquid; Codeine; Reference Standards; Reproducibility of Results; Tablets | 2001 |
A validated HPLC method for the determination of pyridostigmine bromide, acetaminophen, acetylsalicylic acid and caffeine in rat plasma and urine.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Calibration; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2001 |
Spectrophotometric multicomponent analysis of a mixture of metamizol, acetaminophen and caffeine in pharmaceutical formulations by two chemometric techniques.
Topics: Acetaminophen; Algorithms; Caffeine; Chromatography, High Pressure Liquid; Dipyrone; Drug Combinations; Reference Standards; Spectrophotometry, Ultraviolet; Tablets | 2001 |
Quantitative design of optimal analgesic combination of acetaminophen, caffeine, and butalbital.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Barbiturates; Caffeine; Carrageenan; Dose-Response Relationship, Drug; Drug Compounding; Drug Synergism; Female; Male; Mice; Pain; Pain Threshold; Rats; Rats, Wistar | 2001 |
Gene expression changes associated with cytotoxicity identified using cDNA arrays.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Caffeine; Cell Line; Cytotoxins; DNA, Complementary; Gene Expression Profiling; Humans; Liver; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Thioacetamide | 2000 |
Determination of caffeine in pharmaceutical preparations by the linear absorbances method.
Topics: Acetaminophen; Algorithms; Aspirin; Caffeine; Calibration; Drug Combinations; Spectrophotometry, Ultraviolet | 2000 |
Two new spectrophotometric approaches to the multicomponent analysis of the acetaminophen and caffeine in tablets by classical least-squares and principal component regression techniques.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Least-Squares Analysis; Spectrophotometry | 2002 |
Combined effects of acetaminophen, isopropylantipyrine and caffeine on pregnant and nonpregnant liver.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Body Weight; Caffeine; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Liver; Liver Function Tests; Organ Size; Periodic Acid-Schiff Reaction; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar | 2001 |
[Application of statistical simulation spectrophotometry to the determination of four medicaments in feibaosanxiao tablets].
Topics: Acetaminophen; Caffeine; Drug Combinations; Monte Carlo Method; Phenytoin; Spectrophotometry; Tablets; Theophylline | 1998 |
[Treatment of post-dural-puncture headache with intravenous cortisone].
Topics: Acetaminophen; Adult; Analgesics; Anesthesia, Epidural; Anesthesia, Obstetrical; Anti-Inflammatory Agents; Caffeine; Cesarean Section; Diplopia; Dura Mater; Female; Headache; Humans; Hydrocortisone; Injections, Intravenous; Intraoperative Complications; Postoperative Complications; Pregnancy; Puerperal Disorders; Punctures; Tramadol | 2002 |
Effects of prenatal exposure to combination of acetaminophen, isopropylantipyrine and caffeine on intrauterine development in rats.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Embryonic and Fetal Development; Female; Male; Pregnancy; Rats; Rats, Wistar | 2002 |
HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Pharmaceutical Preparations; Phenobarbital; Reproducibility of Results; Tablets | 2002 |
Performance of an in-plane detection cell with integrated waveguides for UV/Vis absorbance measurements on microfluidic separation devices.
Topics: Absorption; Acetaminophen; Ascorbic Acid; Caffeine; Chemical Fractionation; Electrophoresis, Capillary; Ketoprofen; Miniaturization; Spectrophotometry, Ultraviolet | 2002 |
Simultaneous determination of paracetamol and caffeine by flow injection-solid phase spectrometry using C18 silica gel as a sensing support.
Topics: Acetaminophen; Caffeine; Carbon Isotopes; Flow Injection Analysis; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Photometry; Silica Gel; Silicon Dioxide; Spectrophotometry, Ultraviolet | 2002 |
Migraine sufferers are not seeking nor receiving guideline-based care.
Topics: Acetaminophen; Analgesics; Barbiturates; Caffeine; Drug Combinations; Drug Prescriptions; Female; Health Behavior; Humans; Ibuprofen; Male; Migraine Disorders; Nonprescription Drugs; Office Visits; Patient Satisfaction; Practice Guidelines as Topic; United States | 2002 |
Effect of caffeine on acetaminophen hepatotoxicity in cultured hepatocytes treated with ethanol and isopentanol.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Drug Synergism; Enzyme Inhibitors; Ethanol; Hepatocytes; Oxidoreductases, N-Demethylating; Pentanols; Rats; Troleandomycin | 2002 |
The impact of an over-the-counter migraine medication program on quality of life.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Drug Combinations; Drug Prescriptions; Female; Health Status; Humans; Male; Middle Aged; Migraine Disorders; Nonprescription Drugs; Prospective Studies; Quality of Life | 2003 |
Toxicity of acetaminophen, salicylic acid, and caffeine for first-passage rat renal inner medullary collecting duct cells.
Topics: Acetaminophen; Animals; Caffeine; Cell Count; Cell Division; Cells, Cultured; Keratolytic Agents; Kidney Medulla; Kidney Tubules, Collecting; Mice; Rats; Rats, Sprague-Dawley; Salicylic Acid | 2003 |
Caffeine consumption in drivers of heavy vehicles in Turkey.
Topics: Accidents, Traffic; Acetaminophen; Adult; Caffeine; Cross-Sectional Studies; Headache; Humans; Middle Aged; Motor Vehicles; Sleep; Surveys and Questionnaires; Time Factors; Turkey; Visual Acuity | 2003 |
[Research into simultaneous spectrophotometric determination of components in cough syrup by principal component regression method].
Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Caffeine; Chlorpheniramine; Drug Combinations; Expectorants; Guaifenesin; Histamine H1 Antagonists; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2002 |
[Assay for paracetamol by derivative spectrophotometry in compound amantadine tablets].
Topics: Acetaminophen; Amantadine; Antiviral Agents; Caffeine; Drug Combinations; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets | 2002 |
[CLINICAL TRIAL OF LUNEDON AS AN ANALGESIC FOR ELDERLY PATIENTS].
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Caffeine; Codeine; Geriatrics; Humans; Sweden; Thiazines | 1964 |
CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS DETERMINATION OF ASPIRIN, CAFFEINE, AND ACETAMINOPHEN.
Topics: Acetaminophen; Aspirin; Caffeine; Chemistry, Pharmaceutical; Chromatography; Pharmacy; Research; Salicylic Acid | 1964 |
EFFECTS OF ACETYLSALICYLIC ACID, PHENACETIN, PARACETAMOL, AND CAFFEINE ON RENAL TUBULAR EPITHELIUM.
Topics: Acetaminophen; Aspirin; Caffeine; Cell Biology; Coloring Agents; Epithelium; Erythrocytes; Humans; Kidney Tubules; Leukocytes; Phenacetin; Placebos; Staining and Labeling; Toxicology; Urine | 1965 |
Non-particulate (continuous bed or monolithic) restricted-access reversed-phase media for sample clean-up and separation by capillary-format liquid chromatography.
Topics: Acetaminophen; Animals; Aspirin; Benzoates; Caffeine; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Flow Injection Analysis; Organic Chemicals; Silicon Dioxide; Time Factors | 2003 |
Linear regression analysis and its application to the multivariate spectral calibrations for the multiresolution of a ternary mixture of caffeine, paracetamol and metamizol in tablets.
Topics: Acetaminophen; Caffeine; Calibration; Dipyrone; Linear Models; Multivariate Analysis; Pharmaceutical Solutions; Tablets | 2003 |
N-way PLS applied to simultaneous spectrophotometric determination of acetylsalicylic acid, paracetamol and caffeine.
Topics: Acetaminophen; Aspirin; Caffeine; Calibration; Least-Squares Analysis; Spectrophotometry, Ultraviolet | 2004 |
[Migraine therapy with migraine kranit].
Topics: Acetaminophen; Antipyrine; Caffeine; Drug Combinations; Humans; Migraine Disorders; Muscle Relaxants, Central; Papaverine; Phenobarbital | 1951 |
Optimization of the RP-HPLC method for multicomponent analgetic drug determination.
Topics: Acetaminophen; Analgesics; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Indicators and Reagents; Reference Standards; Spectrophotometry, Ultraviolet; Tablets | 2003 |
Component analysis of illicit heroin samples with GC/MS and its application in source identification.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Codeine; Drug Contamination; Gas Chromatography-Mass Spectrometry; Heroin; Illicit Drugs; Morphine Derivatives; Narcotics; Theophylline; Vasodilator Agents | 2004 |
Reversed-phase capillary electrochromatography for the simultaneous determination of acetylsalicylic acid, paracetamol, and caffeine in analgesic tablets.
Topics: Acetaminophen; Acetonitriles; Analgesics; Aspirin; Buffers; Caffeine; Chromatography, Micellar Electrokinetic Capillary; Hydrogen-Ion Concentration; Reference Standards; Reproducibility of Results; Silicon Dioxide; Tablets; Time | 2004 |
Direct and interactive effects of ecologically relevant concentrations of organic wastewater contaminants on Rana pipiens tadpoles.
Topics: Acetaminophen; Animals; Caffeine; Drug Combinations; Drug Synergism; Larva; Motor Activity; Rana pipiens; Reflex, Startle; Sewage; Triclosan; Water Pollution, Chemical | 2004 |
Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Antipyrine; Caffeine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Embryonic Development; Female; Fetal Development; Fetal Weight; Organ Size; Placenta; Pregnancy; Rats; Rats, Wistar; Toxicity Tests | 2004 |
Barbiturate withdrawal following Internet purchase of Fioricet.
Topics: Acetaminophen; Adult; Barbiturates; Caffeine; Drug Combinations; Female; Humans; Internet; Substance Withdrawal Syndrome | 2004 |
Acute onset of bilateral myoclonus in a 16-year-old female.
Topics: Acetaminophen; Acute Disease; Adolescent; Aspirin; Attention Deficit Disorder with Hyperactivity; Caffeine; Dextroamphetamine; Diagnosis, Differential; Drug Combinations; Female; Headache; Humans; Medical History Taking; Myoclonus; Nonprescription Drugs | 2004 |
Sequential injection chromatographic determination of paracetamol, caffeine, and acetylsalicylic acid in pharmaceutical tablets.
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography; Indicators and Reagents; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Tablets | 2004 |
[Experimental study on the pharmacology of 999 ganmaoling, a compound recipe of Chinese and Western materia medica].
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Chlorpheniramine; Common Cold; Drug Combinations; Drug Synergism; Drugs, Chinese Herbal; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Rabbits; Rats; Rats, Sprague-Dawley | 2004 |
Microcosm evaluation of the effects of an eight pharmaceutical mixture to the aquatic macrophytes Lemna gibba and Myriophyllum sibiricum.
Topics: Acetaminophen; Analysis of Variance; Atorvastatin; Biological Assay; Biomass; Caffeine; Carbamazepine; Complex Mixtures; Dose-Response Relationship, Drug; Heptanoic Acids; Heterocyclic Compounds; Levofloxacin; Magnoliopsida; Ofloxacin; Pharmaceutical Solutions; Pyrroles; Sertraline; Sulfamethoxazole; Toxicity Tests; Trimethoprim; Water Pollutants, Chemical | 2004 |
Assay for the simultaneous determination of acetaminophen-caffeine-butalbital in human serum using a monolithic column.
Topics: Acetaminophen; Barbiturates; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Humans | 2004 |
Pure-silica optical waveguides, fiber couplers, and high-aspect ratio submicrometer channels for electrokinetic separation devices.
Topics: Acetaminophen; Caffeine; Electrophoresis, Microchip; Equipment Design; Fiber Optic Technology; Ketoprofen; Microfluidic Analytical Techniques; Silicon Dioxide; Ultraviolet Rays | 2004 |
Thin-layer chromatography and mass spectrometry coupled using desorption electrospray ionization.
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, Thin Layer; Drug Combinations; Food Coloring Agents; Molecular Structure; Organic Chemicals; Rhodamines; Spectrometry, Mass, Electrospray Ionization | 2005 |
Multiple fixed drug eruption due to drug combination.
Topics: Acetaminophen; Aged; Aged, 80 and over; Anti-Bacterial Agents; Caffeine; Diagnosis, Differential; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Levofloxacin; Ofloxacin; Patch Tests; Promethazine; Salicylamides | 2005 |
Content uniformity and dissolution tests of triplicate mixtures by a double divisor-ratio spectra derivative method.
Topics: Acetaminophen; Aspirin; Caffeine; Chlorpheniramine; Chromatography, High Pressure Liquid; Reproducibility of Results; Sensitivity and Specificity; Solubility; Spectrophotometry, Ultraviolet | 2005 |
Mathematical algorithms applied to the multi-linear regression functions for the multicomponent determination of pharmaceutical dosage form containing three-component mixtures.
Topics: Acetaminophen; Algorithms; Aspirin; Caffeine; Pharmaceutical Preparations; Regression Analysis | 2005 |
[Ratio spectrophotometry and its application to assay of compound pharmacy preparations].
Topics: Acetaminophen; Algorithms; Caffeine; Chemistry, Pharmaceutical; Chlorzoxazone; Pharmaceutical Preparations; Reference Standards; Reproducibility of Results; Sodium Benzoate; Spectrophotometry, Ultraviolet | 2005 |
Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoquinones; Biological Transport; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Glutathione; Hepatocytes; Imines; Intestinal Absorption; Liver; Mice; Mice, Inbred C57BL; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcription, Genetic | 2005 |
Glomerular tip lesion associated with nonsteroidal anti-inflammatory drug-induced nephrotic syndrome.
Topics: Accidents, Traffic; Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Barbiturates; Caffeine; Drug Therapy, Combination; Female; Foam Cells; Humans; Ibuprofen; Kidney Glomerulus; Nephrosis, Lipoid; Nephrotic Syndrome; Pain; Tramadol | 2005 |
[Analysis of two year heroin seizures in the Liege area].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; France; Heroin; Law Enforcement; Noscapine; Papaverine | 2005 |
Simultaneous quantitation of five active principles in a pharmaceutical preparation: development and validation of a near infrared spectroscopic method.
Topics: Acetaminophen; Ascorbic Acid; Caffeine; Chlorpheniramine; Dextromethorphan; Guidelines as Topic; Pharmaceutical Preparations; Regression Analysis; Reproducibility of Results; Spectroscopy, Near-Infrared | 2006 |
Effects of three organic wastewater contaminants on American toad, Bufo americanus, tadpoles.
Topics: Acetaminophen; Animals; Anti-Infective Agents, Local; Anti-Inflammatory Agents, Non-Steroidal; Bufonidae; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Larva; Survival; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Modulation of paracetamol antinociception by caffeine and by selective adenosine A2 receptor antagonists in mice.
Topics: Acetaminophen; Adenosine A2 Receptor Antagonists; Analgesics, Non-Narcotic; Animals; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Knockout; Neuroprotective Agents; Nociceptors; Pain; Pain Measurement; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Sulfonic Acids; Time Factors; Triazoles; Xanthines | 2006 |
Botulinum toxin A for the treatment of greater occipital neuralgia and trigeminal neuralgia: a case report with pathophysiological considerations.
Topics: Acetaminophen; Adult; Analgesics; Anxiety; Aspirin; Botulinum Toxins, Type A; Caffeine; Colitis, Ulcerative; Depression; Hashimoto Disease; Humans; Hypertension; Insulin Resistance; Male; Meniere Disease; Neuromuscular Agents; Occipital Bone; Temporomandibular Joint Disorders; Trigeminal Neuralgia | 2006 |
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial--a comment.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Drug Combinations; Humans; Migraine Disorders; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan | 2006 |
A comment on acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Drug Combinations; Humans; Migraine Disorders; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan | 2006 |
Modulation of catecholamine release from rat striatal slices by the fixed combination of aspirin, paracetamol and caffeine.
Topics: Acetaminophen; Animals; Aspirin; Brain; Caffeine; Corpus Striatum; Dopamine; Male; Norepinephrine; Pain; Rats | 2006 |
Desorption electrospray ionization with a portable mass spectrometer: in situ analysis of ambient surfaces.
Topics: Acetamides; Acetaminophen; Aspirin; Atrazine; Caffeine; DEET; Herbicides; Insect Repellents; Organophosphorus Compounds; Plant Leaves; Spectrometry, Mass, Electrospray Ionization; Tablets | 2006 |
Acute migraine treatment: patterns of use and satisfaction in a clinical population.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Drug Combinations; Ergotamine; Female; Health Surveys; Humans; Male; Middle Aged; Migraine Disorders; Narcotics; Nonprescription Drugs; Patient Satisfaction; Recurrence; Serotonin Receptor Agonists; Surveys and Questionnaires | 2006 |
Re: Oral multidose caffeine-paracetamol combination is not effective for the prophylaxis of postdural puncture headache.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Humans; Post-Dural Puncture Headache | 2006 |
Heterotropic and homotropic cooperativity by a drug-metabolising mutant of cytochrome P450 BM3.
Topics: Acetaminophen; Amodiaquine; Arginine; Benzoflavones; Caffeine; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Activation; Humans; Kinetics; Leucine; Molecular Structure; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Pharmaceutical Preparations; Phenylalanine; Substrate Specificity | 2006 |
Acetylsalicylic acid, paracetamol and caffeine combination in headache.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Drug Combinations; Headache; Humans | 2006 |
[Chronic interstitial nephritis in an 18-year-old due to intake of a compound analgesic].
Topics: Acetaminophen; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Caffeine; Creatinine; Drug Combinations; Flank Pain; Headache; Humans; Kidney; Kidney Failure, Chronic; Male; Nephritis, Interstitial; Urography | 2006 |
Simultaneous determination of paracetamol, caffeine and propyphenazone in ternary mixtures by micellar electrokinetic capillary chromatography.
Topics: Acetaminophen; Antipyrine; Caffeine; Chromatography, Micellar Electrokinetic Capillary; Molecular Structure; Reproducibility of Results | 2007 |
The fixed combination of acetylsalicylic acid, paracetamol and caffeine.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Chemistry, Pharmaceutical; Double-Blind Method; Drug Combinations; Headache; Humans; Randomized Controlled Trials as Topic; Selection Bias | 2006 |
Paracetamol inhibits nitric oxide synthesis in murine spinal cord slices.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arginine; Caffeine; Central Nervous System Stimulants; Cerebellum; Citrulline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; In Vitro Techniques; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Spinal Cord | 2007 |
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial--a comment.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Enzyme Inhibitors; Humans; Migraine Disorders | 2007 |
Structure and drug release in a crosslinked poly(ethylene oxide) hydrogel.
Topics: Acetaminophen; Caffeine; Chemistry, Pharmaceutical; Cross-Linking Reagents; Crystallization; Crystallography, X-Ray; Cyclohexanes; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Hydrogels; Microscopy, Atomic Force; Models, Chemical; Molecular Conformation; Molecular Structure; Neutron Diffraction; Phase Transition; Polyethylene Glycols; Scattering, Small Angle; Solubility; Technology, Pharmaceutical; Time Factors; Water | 2007 |
[Current problems in the quality control of pharmaceutical preparations manufactured in pharmacies II. Paracetamol contraining preparations].
Topics: Acetaminophen; Aspirin; Caffeine; Chemistry, Pharmaceutical; Ethylmorphine; Hungary; Quality Control | 2006 |
Is there a relationship between street heroin purity and drug-related emergencies and/or drug-related deaths? An analysis from Vienna, Austria.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Austria; Caffeine; Central Nervous System Stimulants; Drug Contamination; Emergencies; Female; Forensic Toxicology; Heroin; Heroin Dependence; Humans; Illicit Drugs; Lactose; Male; Narcotics; Sweetening Agents | 2007 |
Simultaneous spectrophotometric determination of paracetamol, ibuprofen and caffeine in pharmaceuticals by chemometric methods.
Topics: Acetaminophen; Algorithms; Caffeine; Calibration; Chemistry Techniques, Analytical; Ibuprofen; Least-Squares Analysis; Multivariate Analysis; Neural Networks, Computer; Pharmaceutical Preparations; Spectrophotometry | 2008 |
Rational estimation of the optimum amount of non-fibrous disintegrant applying percolation theory for binary fast disintegrating formulation.
Topics: Acetaminophen; Algorithms; Caffeine; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Diffusion; Drug Compounding; Excipients; Models, Statistical; Particle Size; Porosity; Powders; Tablets; Water | 2008 |
Investigation of hypromellose particle size effects on drug release from sustained release hydrophilic matrix tablets.
Topics: Acetaminophen; Caffeine; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Excipients; Hydrochlorothiazide; Hypromellose Derivatives; Ketoprofen; Methylcellulose; Metoprolol; Molecular Weight; Particle Size; Solubility; Tablets; Theophylline; Viscosity | 2007 |
Cooperative binding of acetaminophen and caffeine within the P450 3A4 active site.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Binding Sites; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Escherichia coli; Glutathione; Humans; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Recombinant Proteins | 2007 |
Evaluation of selected micronized poloxamers as tablet lubricants.
Topics: Acetaminophen; Aspirin; Caffeine; Chemistry, Pharmaceutical; Excipients; Hardness; Hydrophobic and Hydrophilic Interactions; Leucine; Lubricants; Poloxamer; Solubility; Stearic Acids; Surface Properties; Tablets | 2007 |
Coupling desorption electrospray ionisation and neutral desorption/extractive electrospray ionisation with a travelling-wave based ion mobility mass spectrometer for the analysis of drugs.
Topics: Acetaminophen; Analgesics; Anti-Infective Agents, Local; Benzocaine; Caffeine; Chlorhexidine; Codeine; Dentifrices; Drug Combinations; Gels; Pharmaceutical Preparations; Polyethylene Glycols; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Determination of caffeine and associated compounds in food, beverages, natural products, pharmaceuticals, and cosmetics by micellar electrokinetic capillary chromatography.
Topics: Acetaminophen; Antipyrine; Aspirin; Beverages; Biological Products; Caffeine; Chromatography, Micellar Electrokinetic Capillary; Codeine; Cosmetics; Food Analysis; Linear Models; Pharmaceutical Preparations; Salicylic Acid; Theobromine; Theophylline | 2008 |
Ambient aerodynamic ionization source for remote analyte sampling and mass spectrometric analysis.
Topics: Acetaminophen; Caffeine; Natriuretic Peptide, Brain; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Ubiquitin | 2008 |
A tandem mass spectrometry assay for the simultaneous determination of acetaminophen, caffeine, phenytoin, ranitidine, and theophylline in small volume pediatric plasma specimens.
Topics: Acetaminophen; Analgesics; Anticonvulsants; Bronchodilator Agents; Caffeine; Calibration; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Histamine H2 Antagonists; Humans; Infant, Newborn; Phenytoin; Quality Control; Ranitidine; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Theophylline | 2008 |
Multivariate analysis of paracetamol, propiphenazone, caffeine and thiamine in quaternary mixtures by PCR, PLS and ANN calibrations applied on wavelet transform data.
Topics: Acetaminophen; Algorithms; Artificial Intelligence; Caffeine; Calibration; Chemistry, Pharmaceutical; Least-Squares Analysis; Models, Statistical; Multivariate Analysis; Neural Networks, Computer; Pharmaceutical Preparations; Reference Standards; Reproducibility of Results; Solutions; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Thiamine | 2008 |
Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons.
Topics: Acetaminophen; Actins; Animals; Animals, Newborn; Antipyrine; Caffeine; Calcium; Cells, Cultured; Codeine; Dendritic Spines; Drug Combinations; Electric Stimulation; Excitatory Amino Acid Agents; Green Fluorescent Proteins; Hippocampus; Microfilament Proteins; Models, Biological; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Protein Transport; Rats; Receptors, AMPA; RNA, Small Interfering; Ryanodine Receptor Calcium Release Channel; Synaptophysin; Transfection | 2009 |
GC/MS analysis of an herbal dietary supplement containing ephedrine.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Dietary Supplements; Ephedrine; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Heart Rate; Humans; Hypokalemia; Nonprescription Drugs | 2009 |
Simultaneous voltammetric determination of paracetamol and caffeine in pharmaceutical formulations using a boron-doped diamond electrode.
Topics: Acetaminophen; Boron; Caffeine; Calibration; Diamond; Electrodes; Potentiometry; Tablets | 2009 |
Rapid simultaneous determination of paracetamol, amantadine hydrochloride, caffeine and chlorpheniramine maleate in human plasma by liquid chromatography/tandem mass spectrometry.
Topics: Acetaminophen; Amantadine; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Chlorpheniramine; Chromatography, High Pressure Liquid; Histamine H1 Antagonists; Humans; Male; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry | 2009 |
Simultaneous determination of acetylsalicylic acid, paracetamol and caffeine using solid-phase molecular fluorescence and parallel factor analysis.
Topics: Acetaminophen; Analysis of Variance; Aspirin; Caffeine; Chemistry, Pharmaceutical; Pharmaceutical Preparations; Reproducibility of Results; Spectrometry, Fluorescence | 2009 |
Simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma by liquid chromatography-tandem mass spectrometry.
Topics: Acetaminophen; Caffeine; Chlorpheniramine; Chromatography, Liquid; Evaluation Studies as Topic; Humans; Male; Piperidines; Pseudoephedrine; Tandem Mass Spectrometry | 2010 |
Non-destructive determination of the coating film thickness by X-ray powder diffractometry and correlation with the dissolution behavior of film-coated tablets.
Topics: Acetaminophen; Aspirin; Caffeine; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Hypromellose Derivatives; Kinetics; Methylcellulose; Microscopy, Electron, Scanning; Powder Diffraction; Solubility; Surface Properties; Tablets; Technology, Pharmaceutical; Titanium; X-Ray Diffraction | 2010 |
Composition, purity and perceived quality of street cocaine in France.
Topics: Acetaminophen; Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Data Collection; Diltiazem; Drug Contamination; Drug Users; Female; France; Humans; Illicit Drugs; Lidocaine; Male; Middle Aged; Smoking; Young Adult | 2010 |
Two-column sequential injection chromatography--new approach for fast and effective analysis and its comparison with gradient elution chromatography.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Spectrophotometry, Ultraviolet; Tablets | 2010 |
Development of a method for nondestructive NIR transmittance spectroscopic analysis of acetaminophen and caffeine anhydrate in intact bilayer tablets.
Topics: Acetaminophen; Caffeine; Calibration; Least-Squares Analysis; Spectroscopy, Near-Infrared; Tablets | 2010 |
Medication-induced esophageal tattoo in a patient with eosinophilic esophagitis.
Topics: Acetaminophen; Barbiturates; Caffeine; Coloring Agents; Drug Combinations; Eosinophilic Esophagitis; Esophagoscopy; Esophagus; Humans; Male; Middle Aged; Tattooing | 2011 |
Comments on 'Efficacy of fixed combinations of acetylsalicylic acid, acetaminophen and caffeine in the treatment of idiopathic headache: a review'.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Drug Combinations; Humans; Phosphodiesterase Inhibitors; Tension-Type Headache | 2010 |
Transmission electron microscopy of pharmaceutical materials.
Topics: Acetaminophen; Caffeine; Crystallization; Microscopy, Electron, Transmission; Oxalic Acid; Pharmaceutical Preparations; Ranitidine; Theophylline | 2010 |
Potential for biodegradation and sorption of acetaminophen, caffeine, propranolol and acebutolol in lab-scale aqueous environments.
Topics: Acebutolol; Acetaminophen; Adsorption; Biodegradation, Environmental; Caffeine; Cardiovascular Agents; Central Nervous System Stimulants; Clinical Laboratory Techniques; Environmental Restoration and Remediation; Propranolol; Sensory System Agents; Water Pollutants, Chemical | 2010 |
Inkjet printing of drug substances and use of porous substrates-towards individualized dosing.
Topics: Acetaminophen; Administration, Oral; Caffeine; Chromatography, Liquid; Dosage Forms; Mass Spectrometry; Paper; Pharmaceutical Preparations; Porosity; Precision Medicine; Printing; Solutions; Technology, Pharmaceutical; Theophylline | 2011 |
Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments.
Topics: Acetaminophen; Caffeine; Cocaine; Cotinine; Environmental Monitoring; Erythromycin; Halogenation; Illicit Drugs; Iohexol; Kinetics; Nicotine; Osmosis; Ozone; Pharmaceutical Preparations; Ultrafiltration; Water Pollutants, Chemical; Water Pollution, Chemical; Water Purification; Water Supply | 2011 |
A combined desorption ionization by charge exchange (DICE) and desorption electrospray ionization (DESI) source for mass spectrometry.
Topics: Acetaminophen; Caffeine; Ibuprofen; Pharmaceutical Preparations; Pressure; Spectrometry, Mass, Electrospray Ionization | 2011 |
Combining formulation and process aspects for optimizing the high-shear wet granulation of common drugs.
Topics: Acetaminophen; Aspirin; Caffeine; Chemistry, Pharmaceutical; Excipients; Particle Size; Powders; Solubility; Surface Properties; Torque; Wettability | 2011 |
Caffeine inhibits antinociception by acetaminophen in the formalin test by inhibiting spinal adenosine A₁ receptors.
Topics: Acetaminophen; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analgesics; Animals; Caffeine; Gene Deletion; Male; Mice; Pain Measurement; Receptor, Adenosine A1; Receptor, Adenosine A2A; Spinal Cord; Time Factors | 2012 |
Molecular and microscopic assessment of the effects of caffeine, acetaminophen, diclofenac, and their mixtures on river biofilm communities.
Topics: Acetaminophen; Archaea; Bacteria; Biodiversity; Biofilms; Biomass; Caffeine; Carbon; Cyanobacteria; Diclofenac; Rivers; Water Microbiology; Water Pollutants, Chemical | 2012 |
Fast investigations from biological matrices using CE--test of a blood-brain barrier model.
Topics: Acetaminophen; Adsorption; Animals; Blood-Brain Barrier; Caffeine; Carbamazepine; Cell Culture Techniques; Cell Line; Chromatography, Micellar Electrokinetic Capillary; Cimetidine; Humans; Indomethacin; Limit of Detection; Models, Biological; Propranolol; Rats; Reproducibility of Results; Tissue Distribution | 2012 |
Gas chromatographic method validation for the analysis of major components in illicit heroin seized in Malaysia.
Topics: Acetaminophen; Caffeine; Chromatography, Gas; Codeine; Dextromethorphan; Heroin; Malaysia; Morphine; Morphine Derivatives; Reproducibility of Results | 2012 |
Determination of glucosamine and carisoprodol in pharmaceutical formulations by LC with pre-column derivatization and UV detection.
Topics: Acetaminophen; Acetonitriles; Caffeine; Carisoprodol; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Combinations; Glucosamine; Limit of Detection; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets | 2012 |
Suspected opioid overdose case resolved by CYP2D6 genotyping.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Caffeine; Codeine; Cytochrome P-450 CYP2D6; Drug Combinations; Drug Overdose; Female; Genotype; Humans; Pain; Pharmacogenetics | 2012 |
Transmission fourier transform Raman spectroscopy of pharmaceutical tablet cores.
Topics: Absorption; Acetaminophen; Aspirin; Caffeine; Drug Combinations; Fourier Analysis; Organic Chemicals; Spectroscopy, Near-Infrared; Spectrum Analysis, Raman; Tablets | 2012 |
Noninvasive, quantitative analysis of drug mixtures in containers using spatially offset Raman spectroscopy (SORS) and multivariate statistical analysis.
Topics: Acetaminophen; Caffeine; Complex Mixtures; Counterfeit Drugs; Forensic Sciences; Illicit Drugs; Least-Squares Analysis; Multivariate Analysis; Phenylephrine; Principal Component Analysis; Spectrum Analysis, Raman | 2012 |
Internal multiple-scattering hole-enhanced Raman spectroscopy: improved backscattering Fourier transform Raman sampling in pharmaceutical tablets utilizing cylindrical-conical holes.
Topics: Acetaminophen; Aspirin; Caffeine; Drug Combinations; Excipients; Fluorescence; Fourier Analysis; Scattering, Radiation; Signal-To-Noise Ratio; Spectroscopy, Near-Infrared; Spectrum Analysis, Raman; Surface Properties; Tablets | 2012 |
Migraine and proctitis: what is the link?
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Caffeine; Central Nervous System Stimulants; Chronic Disease; Endoscopy, Digestive System; Female; Humans; Migraine Disorders; Opium; Proctitis; Suppositories; Ulcer | 2013 |
Overuse of paracetamol caffeine aspirin powders affects cerebral glucose metabolism in chronic migraine patients.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Chronic Disease; Female; Fluorodeoxyglucose F18; Glucose; Headache Disorders, Secondary; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Migraine Disorders; Neuropsychological Tests; Pain Measurement; Positron-Emission Tomography; Powders; Radiopharmaceuticals | 2013 |
Development of qualitative and quantitative analysis methods in pharmaceutical application with new selective signal excitation methods for 13 C solid-state nuclear magnetic resonance using 1 H T1rho relaxation time.
Topics: Acetaminophen; Antipyrine; beta-Cyclodextrins; Caffeine; Carbon Isotopes; Chemistry, Pharmaceutical; Crystallization; Drug Combinations; Excipients; Indomethacin; Lactose; Magnetic Resonance Spectroscopy; Nifedipine; Pharmaceutical Preparations; Phenacetin; Povidone; Protons; Pyridones; Signal Processing, Computer-Assisted; Technology, Pharmaceutical | 2013 |
Capillary electrophoretic determination of antimigraine formulations containing caffeine, ergotamine, paracetamol and domperidone or metoclopramide.
Topics: Acetaminophen; Caffeine; Domperidone; Drug Combinations; Drug Stability; Electrophoresis, Capillary; Ergotamine; Hydrogen-Ion Concentration; Limit of Detection; Linear Models; Metoclopramide; Migraine Disorders; Osmolar Concentration; Reproducibility of Results; Tablets; Tartrates; Temperature | 2013 |
High-resolution monolithic columns--a new tool for effective and quick separation.
Topics: Acetaminophen; Adsorption; Ascorbic Acid; Caffeine; Chromatography, High Pressure Liquid | 2013 |
Pharmaceutical analysis in solids using front face fluorescence spectroscopy and multivariate calibration with matrix correction by piecewise direct standardization.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Calibration; Central Nervous System Stimulants; Least-Squares Analysis; Spectrometry, Fluorescence | 2013 |
[Rapid identification 15 effective components of anti common cold medicine with MRM by LC-MS/MS].
Topics: Acetaminophen; Acetanilides; Amantadine; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Antipyrine; Caffeine; Chlorpheniramine; Chromatography, Liquid; Diclofenac; Diphenhydramine; Drug Contamination; Drug Stability; Ephedrine; Guaifenesin; Promethazine; Pseudoephedrine; Reproducibility of Results; Salicylates; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China.
Topics: Acetaminophen; Caffeine; Carbamazepine; Carbon; China; Ciprofloxacin; DEET; Environmental Monitoring; Erythromycin; Nitrates; Nitrites; Nitrogen; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Rivers; Sulfamethoxazole; Trimethoprim; Water Pollutants, Chemical; Water Quality | 2013 |
Green chromatography separation of analytes of greatly differing properties using a polyethylene glycol stationary phase and a low-toxic water-based mobile phase.
Topics: Acetaminophen; Acetonitriles; Aminophenols; Antipyrine; Caffeine; Calibration; Chromatography, High Pressure Liquid; Ethylamines; Hydrophobic and Hydrophilic Interactions; Methanol; Polyethylene Glycols; Reproducibility of Results; Tablets; Ultraviolet Rays | 2013 |
[Simultaneous determination of five cold medicine ingredients in paracetamol triprolidine hydrochloride and pseudoephedrine hydrochloride tablets by pH/organic solvent double-gradient high performance liquid chromatography].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antipyretics; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Hydrogen-Ion Concentration; Pseudoephedrine; Salicylamides; Solvents; Tablets; Triprolidine | 2013 |
Sensitivity-enhanced transmission Raman spectroscopy.
Topics: Acetaminophen; Aspirin; Caffeine; Chemistry, Pharmaceutical; Drug Combinations; Drug Industry; Humans; Image Enhancement; Spectrum Analysis, Raman; Surface Properties; Tablets | 2013 |
[Effectiveness of analgesic combinations in the self-medication].
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Drug Combinations; Germany; Humans; Nonprescription Drugs; Self Medication; Treatment Outcome | 2013 |
Levetiracetam interacts synergistically with nonsteroidal analgesics and caffeine to produce antihyperalgesia in rats.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Celecoxib; Drug Synergism; Drug Therapy, Combination; Hyperalgesia; Ibuprofen; Inflammation; Levetiracetam; Male; Piracetam; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2013 |
Genetics of drug-induced hepatotoxicity toxicity in Gilbert's syndrome.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Chemical and Drug Induced Liver Injury; Drug Combinations; Gilbert Disease; Humans; Male; Middle Aged | 2013 |
Evaluation of the hyperbranched polymer Hybrane H1500 for production of matricial controlled-release particles by hot-melt extrusion.
Topics: Acetaminophen; Caffeine; Chemistry, Pharmaceutical; Crystallization; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Stability; Hot Temperature; Kinetics; Particle Size; Polyesters; Porosity; Propanolamines; Solubility | 2014 |
Adsorption characteristics of selected hydrophilic and hydrophobic micropollutants in water using activated carbon.
Topics: 2,4-Dichlorophenoxyacetic Acid; Acetaminophen; Adsorption; Atrazine; Caffeine; Carbanilides; Carbon; Diclofenac; Endocrine Disruptors; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Naproxen; Pesticides; Pharmaceutical Preparations; Sulfamethazine; Sulfamethoxazole; Temperature; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2014 |
Ambient molecular imaging by laser ablation atmospheric pressure chemical ionization mass spectrometry.
Topics: Acetaminophen; Caffeine; Chromatography, Thin Layer; Laser Therapy; Molecular Imaging; Molecular Weight; Spectrometry, Mass, Electrospray Ionization; Tablets; Thyroxine | 2013 |
Natural attenuation of pharmaceuticals and an illicit drug in a laboratory column experiment.
Topics: Acetaminophen; Caffeine; Equipment Design; Geologic Sediments; Groundwater; Humans; Illicit Drugs; Methamphetamine; Silicon Dioxide; Water Pollutants, Chemical; Water Purification | 2014 |
Sensitive and selective cocaine electrochemical detection using disposable sensors.
Topics: Acetaminophen; Anesthetics, Local; Caffeine; Cocaine; Codeine; Electrochemical Techniques; Electrodes; Least-Squares Analysis; Limit of Detection; Nanotubes, Carbon; Oxidation-Reduction; Reproducibility of Results; Substance Abuse Detection | 2014 |
Chars from gasification of coal and pine activated with K2CO3: acetaminophen and caffeine adsorption from aqueous solutions.
Topics: Acetaminophen; Adsorption; Caffeine; Carbonates; Coal; Pinus; Porosity; Potassium; Wood | 2014 |
The impact of different proportions of a treated effluent on the biotransformation of selected micro-contaminants in river water microcosms.
Topics: Acetaminophen; Biotransformation; Caffeine; Carbamazepine; Metoprolol; Pharmaceutical Preparations; Rivers; Sewage; Tetrazoles; Valine; Valsartan; Waste Disposal, Fluid; Water Pollutants, Chemical | 2014 |
Fast dissolving paracetamol/caffeine nanofibers prepared by electrospinning.
Topics: Acetaminophen; Administration, Sublingual; Caffeine; Drug Combinations; Drug Delivery Systems; Drug Liberation; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Molecular Structure; Nanofibers; Solubility; Surface Properties; Technology, Pharmaceutical; Time Factors | 2014 |
Lethal and sublethal effects of selected PPCPs on the freshwater rotifer, Plationus patulus.
Topics: Acetaminophen; Animals; Caffeine; Cosmetics; Fluoxetine; Food Chain; Fresh Water; Lethal Dose 50; Mexico; Pharmaceutical Preparations; Rotifera; Triclosan; Water Pollutants, Chemical; Water Pollution, Chemical | 2015 |
Predicting the excess solubility of acetanilide, acetaminophen, phenacetin, benzocaine, and caffeine in binary water/ethanol mixtures via molecular simulation.
Topics: Acetaminophen; Acetanilides; Benzocaine; Caffeine; Ethanol; Models, Molecular; Pharmaceutical Preparations; Phenacetin; Solubility; Solvents; Water | 2015 |
Zone fluidics for measurement of octanol-water partition coefficient of drugs.
Topics: 1-Octanol; Acetaminophen; Aniline Compounds; Caffeine; Equipment Design; Ibuprofen; Imidazoles; Riboflavin; Water | 2015 |
Simultaneous determination of caffeine, paracetamol, and ibuprofen in pharmaceutical formulations by high-performance liquid chromatography with UV detection and by capillary electrophoresis with conductivity detection.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Ibuprofen; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet | 2015 |
Sex differences in liver toxicity-do female and male human primary hepatocytes react differently to toxicants in vitro?
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Calcium; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Chlorpromazine; Diclofenac; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Hepatocytes; Humans; Male; Membrane Potential, Mitochondrial; Omeprazole; Primary Cell Culture; Sex Characteristics; Verapamil | 2015 |
Comprehensive quantification of tablets with multiple active pharmaceutical ingredients using transmission Raman spectroscopy--a proof of concept study.
Topics: Acetaminophen; Caffeine; Calibration; Excipients; Least-Squares Analysis; Models, Theoretical; Multivariate Analysis; Phenylephrine; Reproducibility of Results; Spectrum Analysis, Raman; Tablets | 2015 |
An investigation into the influence of drug-polymer interactions on the miscibility, processability and structure of polyvinylpyrrolidone-based hot melt extrusion formulations.
Topics: Acetaminophen; Caffeine; Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Hot Temperature; Hydrogen Bonding; Polymers; Povidone; Solubility; Transition Temperature; Vinyl Compounds | 2015 |
Molecular Ionization-Desorption Analysis Source (MIDAS) for Mass Spectrometry: Thin-Layer Chromatography.
Topics: Acetaminophen; Caffeine; Calibration; Chromatography, Thin Layer; Equipment Design; Mass Spectrometry; Salicylamides | 2016 |
3D Printing of Medicines: Engineering Novel Oral Devices with Unique Design and Drug Release Characteristics.
Topics: Acetaminophen; Caffeine; Drug Compounding; Drug Liberation; Humans; Polymers; Printing, Three-Dimensional; Tablets; Technology, Pharmaceutical | 2015 |
Adsorption of pharmaceuticals onto activated carbon fiber cloths - Modeling and extrapolation of adsorption isotherms at very low concentrations.
Topics: Acetaminophen; Adsorption; Caffeine; Carbamazepine; Carbon; Carbon Fiber; Charcoal; Diclofenac; Models, Theoretical; Reproducibility of Results; Water Purification | 2016 |
Pharmacokinetic Herb-Drug Interaction between Essential Oil of Aniseed (Pimpinella anisum L., Apiaceae) and Acetaminophen and Caffeine: A Potential Risk for Clinical Practice.
Topics: Acetaminophen; Allylbenzene Derivatives; Animals; Anisoles; Caffeine; Fruit; Gas Chromatography-Mass Spectrometry; Herb-Drug Interactions; Male; Mice; Oils, Volatile; Parasympatholytics; Pimpinella; Plant Oils | 2016 |
Culex quinquefasciatus larval microbiomes vary with instar and exposure to common wastewater contaminants.
Topics: Acetaminophen; Animals; Anti-Bacterial Agents; Bacteria; Caffeine; Culex; DNA, Bacterial; Hormones; Larva; Microbiota; Polymerase Chain Reaction; Principal Component Analysis; Sequence Analysis, DNA; Wastewater; Water Pollutants, Chemical | 2016 |
The role of sorption and biodegradation in the removal of acetaminophen, carbamazepine, caffeine, naproxen and sulfamethoxazole during soil contact: A kinetics study.
Topics: Acetaminophen; Adsorption; Biodegradation, Environmental; Caffeine; Carbamazepine; Kinetics; Models, Chemical; Naproxen; Soil; Soil Pollutants; Spain; Sulfamethoxazole; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2016 |
Evaluation of the efficiency of continuous wavelet transform as processing and preprocessing algorithm for resolution of overlapped signals in univariate and multivariate regression analyses; an application to ternary and quaternary mixtures.
Topics: Acetaminophen; Algorithms; Aminophenols; Analgesics; Caffeine; Central Nervous System Stimulants; Least-Squares Analysis; Multivariate Analysis; Papaverine; Spectrophotometry; Wavelet Analysis | 2016 |
Medication Overuse Headache Due to Butalbital, Acetaminophen, and Caffeine Tablets.
Topics: Acetaminophen; Analgesics; Barbiturates; Caffeine; Drug Combinations; Headache Disorders, Secondary; Humans; Migraine Disorders; Quality of Life | 2016 |
New potential humic acid stationary phase toward drug components: Development of a chemometric-assisted RP-HPLC method for the determination of paracetamol and caffeine in tablet formulations.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Drug Compounding; Humic Substances; Tablets | 2016 |
Simultaneous determination of caffeine and paracetamol by square wave voltammetry at poly(4-amino-3-hydroxynaphthalene sulfonic acid)-modified glassy carbon electrode.
Topics: Acetaminophen; Caffeine; Carbon; Electrochemical Techniques; Electrodes; Naphthalenesulfonates | 2016 |
Graphene/Nafion composite film modified glassy carbon electrode for simultaneous determination of paracetamol, aspirin and caffeine in pharmaceutical formulations.
Topics: Acetaminophen; Aspirin; Caffeine; Carbon; Electrochemical Techniques; Electrodes; Fluorocarbon Polymers; Graphite; Reproducibility of Results; Tablets | 2016 |
Ocfentanil overdose fatality in the recreational drug scene.
Topics: Acetaminophen; Adolescent; Caffeine; Chromatography, Liquid; Drug Overdose; Fatal Outcome; Humans; Illicit Drugs; Male; Mass Spectrometry; Piperidines; Postmortem Changes | 2016 |
Quantification of Pharmaceutical Compounds Based on Powder X-Ray Diffraction with Chemometrics.
Topics: Acetaminophen; Caffeine; Lactose; Powder Diffraction; Powders | 2016 |
Offline solid-phase extraction for preconcentration of pharmaceuticals and personal care products in environmental water and their simultaneous determination using the reversed phase high-performance liquid chromatography method.
Topics: Acetaminophen; Benzophenones; Caffeine; Carbanilides; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Ciprofloxacin; Cities; Cosmetics; Environmental Monitoring; India; Limit of Detection; Reproducibility of Results; Rivers; Sensitivity and Specificity; Sewage; Solid Phase Extraction; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2016 |
Occurrence and preliminarily environmental risk assessment of selected pharmaceuticals in the urban rivers, China.
Topics: Acetaminophen; Animals; Caffeine; China; Chlorophyta; Ecotoxicology; Environmental Monitoring; Humans; Pharmaceutical Preparations; Risk Assessment; Rivers; Urban Population; Water Pollutants, Chemical; Water Quality | 2016 |
Emerging pollutant mixture mineralization by TiO
Topics: Acetaminophen; Caffeine; Catalysis; Photolysis; Spectrometry, Mass, Electrospray Ionization; Tetracycline; Titanium; Ultraviolet Rays; Water; Water Pollutants, Chemical | 2017 |
Fused-filament 3D printing of drug products: Microstructure analysis and drug release characteristics of PVA-based caplets.
Topics: Acetaminophen; Bicarbonates; Caffeine; Drug Liberation; Polyvinyl Alcohol; Porosity; Printing, Three-Dimensional; Solubility; Tablets; Technology, Pharmaceutical | 2016 |
Assessing 2D electrophoretic mobility spectroscopy (2D MOSY) for analytical applications.
Topics: Acetaminophen; Amino Acids; Aspirin; Caffeine; Complex Mixtures; Diffusion; Electrophoretic Mobility Shift Assay; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Tablets | 2017 |
Multiscale modeling reveals inhibitory and stimulatory effects of caffeine on acetaminophen-induced toxicity in humans.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Therapy, Combination; Humans; Models, Biological; Pain; Precision Medicine | 2017 |
Investigating natural attenuation of pharmaceuticals through unsaturated column tests.
Topics: Acetaminophen; Caffeine; Carbamazepine; Kinetics; Naproxen; Nonlinear Dynamics; Pharmaceutical Preparations; Soil; Soil Pollutants; Sulfamethoxazole; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2017 |
Exploiting the high oxidation potential of carisoprodol on a boron-doped diamond electrode: an improved method for its simultaneous determination with acetaminophen and caffeine.
Topics: Acetaminophen; Boron; Caffeine; Carisoprodol; Diamond; Electrodes; Reproducibility of Results | 2017 |
Answer to the Letter to the Editor Concerning "Pharmacokinetics in Morbid Obesity: Influence of Two Bariatric Surgery Techniques on Paracetamol and Caffeine Metabolism".
Topics: Acetaminophen; Bariatric Surgery; Caffeine; Gastric Bypass; Humans; Obesity, Morbid | 2017 |
Letter in Reply to Arno et al. "Pharmacokinetics in Morbid Obesity: Influence of Two Bariatric Surgery Techniques on Paracetamol and Caffeine Metabolism".
Topics: Acetaminophen; Bariatric Surgery; Caffeine; Gastric Bypass; Humans; Obesity, Morbid | 2017 |
Printing of small molecular medicines from the vapor phase.
Topics: Acetaminophen; Biological Availability; Caffeine; Drug Delivery Systems; Drug Discovery; Drug Evaluation, Preclinical; Nitriles; Printing; Sulfones; Tamoxifen; X-Ray Diffraction | 2017 |
Acetaminophen plus caffeine or plus codeine probably results in less pain but more swelling in patients undergoing placement of a single implant without bone grafting in the posterior zone.
Topics: Acetaminophen; Bone Transplantation; Caffeine; Codeine; Humans; Pain, Postoperative | 2018 |
Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics.
Topics: Acetaminophen; Animals; Antioxidants; Caffeine; Chemical and Drug Induced Liver Injury; Energy Metabolism; Hepatocytes; Lipid Peroxidation; Liver; Male; Mice; Mitochondria; Mitochondria, Liver; Oxidative Stress; Reactive Oxygen Species | 2018 |
Determination of Acetaminophen, Dexchlorpheniramine, Caffeine, Cotinine and Salicylic acid in 100 μL of Whole Blood by UHPLC-MS/MS.
Topics: Acetaminophen; Autopsy; Caffeine; Child, Preschool; Chlorpheniramine; Chromatography, High Pressure Liquid; Cotinine; Drug-Related Side Effects and Adverse Reactions; Humans; Infant; Salicylic Acid; Tandem Mass Spectrometry | 2018 |
Characteristics of the use of cold combination products among older ambulatory patients at the National Hospital Organization Tochigi Medical Center in Japan: a retrospective single-center observational study.
Topics: Acetaminophen; Aged; Aged, 80 and over; Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Caffeine; Common Cold; Drug Combinations; Drug Prescriptions; Electronic Health Records; Female; Follow-Up Studies; Histamine H1 Antagonists; Hospitals; Humans; Japan; Male; Retrospective Studies | 2017 |
Development of paracetamol-caffeine co-crystals to improve compressional, formulation and in vivo performance.
Topics: Acetaminophen; Animals; Caffeine; Chemistry, Pharmaceutical; Crystallization; Hardness; Powders; Sheep; Solubility; Tablets; Tensile Strength | 2018 |
Simultaneous determination of isoproterenol, acetaminophen, folic acid, propranolol and caffeine using a sensor platform based on carbon black, graphene oxide, copper nanoparticles and PEDOT:PSS.
Topics: Acetaminophen; Bridged Bicyclo Compounds, Heterocyclic; Caffeine; Copper; Folic Acid; Graphite; Isoproterenol; Metal Nanoparticles; Molecular Structure; Oxides; Particle Size; Polymers; Polystyrenes; Propranolol; Soot | 2018 |
Chitosan/waste coffee-grounds composite: An efficient and eco-friendly adsorbent for removal of pharmaceutical contaminants from water.
Topics: Acetaminophen; Adsorption; Aspirin; Caffeine; Chitosan; Coffee; Dipyrone; Kinetics; Pharmaceutical Preparations; Water Purification | 2018 |
Cellulose membrane modified with polypyrrole as an extraction device for the determination of emerging contaminants in river water with gas chromatography-mass spectrometry.
Topics: Acetaminophen; Benzhydryl Compounds; Brazil; Caffeine; Cellulose; Gas Chromatography-Mass Spectrometry; Phenols; Polymers; Pyrroles; Rivers; Solid Phase Extraction; Water Pollutants, Chemical | 2018 |
Direct detection of the triphenylpyrylium-derived short-lived intermediates in the photocatalyzed degradation of acetaminophen, acetamiprid, caffeine and carbamazepine.
Topics: Acetaminophen; Benzene Derivatives; Caffeine; Carbamazepine; Light; Neonicotinoids; Oxidation-Reduction; Photolysis | 2018 |
Determination of synthetic pharmaceutical adulterants in herbal weight gain supplements sold in herb shops, Tehran, Iran.
Topics: Acetaminophen; Caffeine; Cyproheptadine; Dexamethasone; Dietary Supplements; Drug Contamination; Humans; Iran; Phytochemicals; Sildenafil Citrate; Tramadol; Weight Gain | 2018 |
Dietary effects of Sideritis scardica "mountain tea" on human in vivo activities of xenobiotic metabolizing enzymes in healthy subjects.
Topics: Acetaminophen; Adult; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Dietary Exposure; Female; Glucuronosyltransferase; Healthy Volunteers; Herb-Drug Interactions; Humans; Male; Middle Aged; Plant Components, Aerial; Saliva; Sideritis; Substrate Specificity; Teas, Herbal; Xanthine Oxidase; Xenobiotics; Young Adult | 2018 |
Detection of Cutting Agents in Drug-Positive Seized Exhibits within the United States.
Topics: Acetaminophen; Caffeine; Chromatography, Liquid; Drug Contamination; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Kentucky; Levamisole; Procaine; Quinidine; Quinine; Vermont | 2019 |
Multi-Spheres Adsorptive Microextraction (MSAμE)-Application of a Novel Analytical Approach for Monitoring Chemical Anthropogenic Markers in Environmental Water Matrices.
Topics: Acetaminophen; Adsorption; Caffeine; Charcoal; Chromatography, High Pressure Liquid; Limit of Detection; Solid Phase Microextraction; Water; Water Pollutants, Chemical | 2019 |
Fast Raman chemical imaging of tablets with non-flat surfaces.
Topics: Acetaminophen; Aspirin; Caffeine; Cellulose; Least-Squares Analysis; Spectrum Analysis, Raman; Tablets; Technology, Pharmaceutical | 2019 |
Stability-indicating HPLC method for simultaneous quantification of 14 impurities in excedrin tablet formulations and identification of new impurity by LC-MS in accelerated stability studies.
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Drug Contamination; Limit of Detection; Linear Models; Reproducibility of Results | 2019 |
Effect of Genetic Algorithm-Based Wavelength Selection as a Preprocessing Tool on Multivariate Simultaneous Determination of Paracetamol, Orphenadrine Citrate, and Caffeine in the Presence of p-Aminophenol Impurity.
Topics: Acetaminophen; Algorithms; Aminophenols; Caffeine; Calibration; Least-Squares Analysis; Orphenadrine | 2020 |
Different techniques for overlapped UV spectra resolution of some co-administered drugs with paracetamol in their combined pharmaceutical dosage forms.
Topics: Acetaminophen; Caffeine; Diclofenac; Linear Models; Models, Chemical; Orphenadrine; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2020 |
Commercial Screen-Printed Electrodes Based on Carbon Nanomaterials for a Fast and Cost-Effective Voltammetric Determination of Paracetamol, Ibuprofen and Caffeine in Water Samples.
Topics: Acetaminophen; Caffeine; Electrochemistry; Electrodes; Ibuprofen; Limit of Detection; Nanostructures; Nanotubes, Carbon; Reproducibility of Results; Wastewater; Water Pollutants, Chemical | 2019 |
Development and Validation of Chromatographic Methods for Simultaneous Determination of Paracetamol, Orphenadrine Citrate and Caffeine in Presence of P-aminophenol; Quantification of P-aminophenol Nephrotoxic Impurity Using LC-MS/MS.
Topics: Acetaminophen; Aminophenols; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Reverse-Phase; Chromatography, Thin Layer; Densitometry; Drug Contamination; Excipients; Orphenadrine; Tablets; Tandem Mass Spectrometry | 2020 |
A novel all-3D-printed cell-on-a-chip device as a useful electroanalytical tool: Application to the simultaneous voltammetric determination of caffeine and paracetamol.
Topics: Acetaminophen; Caffeine; Electrochemistry; Lab-On-A-Chip Devices; Printing, Three-Dimensional; Time Factors | 2020 |
Isotopomics by isotope ratio monitoring by
Topics: Acetaminophen; Analgesics, Opioid; Caffeine; Carbon Isotopes; Drug Trafficking; Heroin; Illicit Drugs; Magnetic Resonance Spectroscopy; Mass Spectrometry | 2020 |
Validated ecofriendly chromatographic method for quantitative determination of anti-migraine quaternary mixture.
Topics: Acetaminophen; Caffeine; Chromatography, Thin Layer; Drug Compounding; Ergotamine; Metoclopramide; Molecular Structure | 2020 |
Assessment of Sucralose, Caffeine and Acetaminophen as Anthropogenic Tracers in Aquatic Systems Across Florida.
Topics: Acetaminophen; Caffeine; Ecosystem; Environmental Monitoring; Florida; Humans; Sucrose; Sweetening Agents; Wastewater; Water; Water Pollutants, Chemical | 2020 |
Chemometric assisted UV spectrophotometric and RP-HPLC methods for simultaneous determination of paracetamol, diphenhydramine, caffeine and phenylephrine in tablet dosage form.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Diphenhydramine; Phenylephrine; Spectrophotometry, Ultraviolet; Tablets | 2020 |
Simultaneous Determination of Paracetamol, Propyphenazone and Caffeine in Presence of Paracetamol Impurities Using Dual-Mode Gradient HPLC and TLC Densitometry Methods.
Topics: Acetaminophen; Aminophenols; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Densitometry; Drug Combinations; Drug Contamination; Limit of Detection; Meprobamate; Nitrophenols; Reproducibility of Results; Sensitivity and Specificity; Solvents; Tablets | 2021 |
Photocatalytic degradation of acetaminophen and caffeine using magnetite-hematite combined nanoparticles: kinetics and mechanisms.
Topics: Acetaminophen; Caffeine; Catalysis; Ferric Compounds; Ferrosoferric Oxide; Humans; Kinetics; Magnetite Nanoparticles; Titanium; Water Pollutants, Chemical | 2021 |
Diagnosis of Agglomeration and Crystallinity of Active Pharmaceutical Ingredients in Over the Counter Headache Medication by Electrospray Laser Desorption Ionization Mass Spectrometry Imaging.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Caffeine; Headache; Lasers; Nonprescription Drugs; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tablets | 2021 |
Electrochemical sensing platform based on covalent organic framework materials and gold nanoparticles for high sensitivity determination of theophylline and caffeine.
Topics: Acetaminophen; Caffeine; Capsules; Drug Contamination; Electrochemical Techniques; Electrodes; Gold; Limit of Detection; Metal Nanoparticles; Metal-Organic Frameworks; Reproducibility of Results; Tea; Theophylline | 2021 |
Caffeine disrupts ataxia telangiectasia mutated gene-related pathways and exacerbates acetaminophen toxicity in human fetal immortalized hepatocytes.
Topics: Acetaminophen; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Line, Transformed; Cell Survival; Cells, Cultured; Central Nervous System Stimulants; Fetus; Hepatocytes; Humans; Organoids | 2021 |
Synthesis of a biobased resin and its screening as an alternative adsorbent for organic and inorganic micropollutant removal.
Topics: 2,4-Dichlorophenoxyacetic Acid; Acetaminophen; Adsorption; Atrazine; Biocompatible Materials; Caffeine; Carbon; Diclofenac; Diuron; Flame Retardants; Kinetics; Lead; Methylene Blue; Oxidants; Phenols; Proanthocyanidins; Water; Water Pollutants, Chemical; Water Purification | 2022 |
Occurrence of pharmaceuticals and cocaine in the urban drainage channels located on the outskirts of the São Vicente Island (São Paulo, Brazil) and related ecological risk assessment.
Topics: Acetaminophen; Brazil; Caffeine; Carbamazepine; Cocaine; Environmental Monitoring; Humans; Losartan; Pharmaceutical Preparations; Risk Assessment; Water Pollutants, Chemical | 2022 |
First report on the occurrence of pharmaceuticals and cocaine in the coastal waters of Santa Catarina, Brazil, and its related ecological risk assessment.
Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Cosmetics; Diclofenac; Ecosystem; Environmental Monitoring; Humans; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Sewage; Solid Waste; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical | 2022 |
Predictive models for determining treatment response to nonprescription acute medications in migraine: Results from the American Migraine Prevalence and Prevention Study.
Topics: Acetaminophen; Caffeine; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Nonprescription Drugs; Pain; Prevalence; United States | 2022 |
Simultaneous Determination of Paracetamol, Ibuprofen, and Caffeine in Tablets by Molecular Absorption Spectroscopy Combined with Classical Least Square Method.
Topics: Acetaminophen; Caffeine; Ibuprofen; Least-Squares Analysis; Reproducibility of Results; Spectrophotometry; Tablets | 2022 |
A Recent Review On 3D-Printing: Scope and Challenges with Special Focus on Pharmaceutical Field.
Topics: Acetaminophen; Aspirin; Caffeine; Chloramphenicol; Humans; Naproxen; Prednisolone; Printing, Three-Dimensional; Tablets; Technology, Pharmaceutical | 2022 |
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil.
Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2022 |
In Utero Exposure to Caffeine and Acetaminophen, the Gut Microbiome, and Neurodevelopmental Outcomes: A Prospective Birth Cohort Study.
Topics: Acetaminophen; Bacteria; Birth Cohort; Caffeine; Cohort Studies; Female; Gastrointestinal Microbiome; Humans; Pregnancy; Prospective Studies; RNA, Ribosomal, 16S | 2022 |
Fecal indicator bacteria levels at a marine beach before, during, and after the COVID-19 shutdown period and associations with decomposing seaweed and human presence.
Topics: Acetaminophen; Animals; Bacteria; Bathing Beaches; Caffeine; COVID-19; Dogs; Enterococcus; Environmental Monitoring; Feces; Humans; Ibuprofen; Naproxen; Seaweed; Water; Water Microbiology | 2022 |
A DFT study of the interaction of aspirin, paracetamol and caffeine with one water molecule.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Hydrogen Bonding; Water | 2022 |
Determination of ofloxacin in the presence of dopamine, paracetamol, and caffeine using a glassy carbon electrode based on carbon nanomaterials and gold nanoparticles.
Topics: Acetaminophen; Caffeine; Carbon; Chitosan; Dopamine; Electrodes; Gold; Graphite; Metal Nanoparticles; Ofloxacin; Pharmaceutical Preparations; Water | 2022 |
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin Gene-Related Peptide Receptor Antagonists; Child; Diclofenac; Female; Headache; Humans; Ibuprofen; Migraine Disorders; Morphine Derivatives; Naproxen; Nasal Sprays; Pregnancy; Prochlorperazine; Taiwan; Tramadol; Tryptamines | 2022 |
A reversed-phase-high performance liquid chromatography method for simultaneous determination of paracetamol, caffeine, drotaverine HCl and their related impurities with dissolution profiling of their tablets and greenness profile assessment.
Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Solubility; Tablets | 2023 |
Voltammetric Determination of 3-Methylmorphine Using Glassy Carbon Electrode Modified with rGO and Bismuth Film.
Topics: Acetaminophen; Ascorbic Acid; Bismuth; Caffeine; Carbon; Cellulose; Chitosan; Electrochemical Techniques; Electrodes; Graphite; Humic Substances; Limit of Detection; Povidone; Silicon Dioxide; Urea; Water | 2022 |
Heroin detection in a droplet hosted in a 3D printed support at the miniaturized electrified liquid-liquid interface.
Topics: Acetaminophen; Caffeine; Heroin; Printing, Three-Dimensional; Reproducibility of Results | 2022 |
Enhanced fluorimetric detection of diphenylpyraline HCl using micelle and cyclodextrin mediated approach: Spectrofluorimetric and micellar liquid chromatographic application for either single or combined formulation with caffeine and paracetamol.
Topics: Acetaminophen; Caffeine; Humans; Indicators and Reagents; Micelles; Spectrometry, Fluorescence; Tablets | 2023 |
An effective and stability-indicating method development and optimization utilizing the Box-Behnken design for the simultaneous determination of acetaminophen, caffeine, and aspirin in tablet formulation.
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Tablets | 2023 |
Predictors of treatment-response to caffeine combination products, acetaminophen, acetylsalicylic acid (aspirin), and nonsteroidal anti-inflammatory drugs in acute treatment of episodic migraine.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Female; Humans; Hyperalgesia; Male; Middle Aged; Migraine Disorders; Nonprescription Drugs | 2023 |
Assessment of selected pharmaceuticals in Riyadh wastewater treatment plants, Saudi Arabia: Mass loadings, seasonal variations, removal efficiency and environmental risk.
Topics: Acetaminophen; Anti-Bacterial Agents; Biopharmaceutics; Caffeine; Environmental Monitoring; Saudi Arabia; Seasons; Wastewater; Water Pollutants; Water Purification | 2023 |
Effect of Sample Plates and Sample Matrix on the Quantification Capabilities of Surface-Assisted Flowing Atmospheric-Pressure Afterglow Mass Spectrometry (SA-FAPA-MS).
Topics: Acetaminophen; Caffeine; Mass Spectrometry; Nicotine; Progesterone | 2023 |
Environmental Risk Assessment of Drugs in Tropical Freshwaters Using Ceriodaphnia silvestrii as Test Organism.
Topics: Acetaminophen; Animals; Caffeine; Cladocera; Diclofenac; Fresh Water; Ketoprofen; Risk Assessment; Salicylic Acid; Water Pollutants, Chemical | 2023 |
Use of Physiologically Based Pharmacokinetic Modeling for Hepatically Cleared Drugs in Pregnancy: Regulatory Perspective.
Topics: Acetaminophen; Benzodiazepines; Caffeine; Clindamycin; Female; Glucuronosyltransferase; Humans; Pregnancy | 2023 |
The photolytic breakdown of caffeine and paracetamol residues in surface water.
Topics: Acetaminophen; Caffeine; Pharmaceutical Preparations; Photolysis; Sunlight; Wastewater; Water; Water Pollutants, Chemical | 2023 |
Analyzing microbial communities and their biodegradation of multiple pharmaceuticals in membrane bioreactors.
Topics: Acetaminophen; Atenolol; Biodegradation, Environmental; Bioreactors; Caffeine; Environmental Pollutants; Ibuprofen; Microbiota; Pharmaceutical Preparations; RNA, Ribosomal, 16S; Water Pollutants, Chemical | 2023 |
Occurrence and risk assessment of pharmaceuticals in hospital wastewater in Costa Rica.
Topics: Acetaminophen; Anti-Bacterial Agents; Caffeine; Costa Rica; Environmental Monitoring; Hospitals; Ibuprofen; Pharmaceutical Preparations; Risk Assessment; Wastewater; Water Pollutants, Chemical | 2023 |
On-farm Occurrence of Pharmaceuticals and Their Environmental Hazard: Case Study of a Tropical Dairy farm.
Topics: Acetaminophen; Animals; Caffeine; Carbamazepine; Environmental Monitoring; Farms; Ibuprofen; Ketoprofen; Pharmaceutical Preparations; Risperidone; Wastewater; Water; Water Pollutants, Chemical | 2023 |