caffeine and 4-hydroxymephenytoin

caffeine has been researched along with 4-hydroxymephenytoin in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (25.00)	18.2507
2000's	3 (75.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Caslavska, J; Desiderio, C; Hufschmid, E; Theurillat, R; Thormann, W; Wolfisberg, H	1
Chen, XP; Huang, SL; Huang, Z; Ou-Yang, DS; Tan, ZR; Zhou, HH	1
Abd El-Aty, AM; An, W; Chen, GL; Li, Q; Li, Z; Liu, J; Tang, ZR; Wang, D; Wang, LS; Wu, J; Zhou, G; Zhou, HH; Zhu, B	1
Branch, RA; Chaves-Gnecco, D; Frye, RF; Matzke, GR; Rabinovitz, M; Shaikh, OS; Zgheib, NK	1

Trials

3 trial(s) available for caffeine and 4-hydroxymephenytoin

Article	Year
Screening for hydroxylation and acetylation polymorphisms in man via simultaneous analysis of urinary metabolites of mephenytoin, dextromethorphan and caffeine by capillary electrophoretic procedures. Journal of chromatography. B, Biomedical applications, 1994, Jun-03, Volume: 656, Issue:1 Topics: Acetylation; Adult; Biotransformation; Caffeine; Chromatography, High Pressure Liquid; Dextromethorphan; Electrophoresis, Polyacrylamide Gel; Humans; Hydroxylation; Mephenytoin; Middle Aged; Phenotype; Polymorphism, Genetic	1994
The influence of St John's Wort on CYP2C19 activity with respect to genotype. Journal of clinical pharmacology, 2004, Volume: 44, Issue:6 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Genotype; Humans; Hypericum; Male; Mephenytoin; Mixed Function Oxygenases; Plant Extracts; Polymorphism, Genetic	2004
Liver disease selectively modulates cytochrome P450--mediated metabolism. Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3 Topics: Administration, Oral; Adult; Anticonvulsants; Antihypertensive Agents; Caffeine; Case-Control Studies; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Isoenzymes; Liver Diseases; Male; Mephenytoin; Middle Aged; Muscle Relaxants, Central; Phosphodiesterase Inhibitors; Severity of Illness Index; Theophylline	2006

Other Studies

1 other study(ies) available for caffeine and 4-hydroxymephenytoin

Article	Year
Isozyme-specific induction of low-dose aspirin on cytochrome P450 in healthy subjects. Clinical pharmacology and therapeutics, 2003, Volume: 73, Issue:3 Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Asian People; Aspirin; Caffeine; China; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Isoenzymes; Male; Mephenytoin; Metoprolol; Midazolam; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenotype; Reference Values; Theophylline	2003

Article

Year

Isozyme-specific induction of low-dose aspirin on cytochrome P450 in healthy subjects.

Clinical pharmacology and therapeutics, 2003, Volume: 73, Issue:3

Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Asian People; Aspirin; Caffeine; China; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Isoenzymes; Male; Mephenytoin; Metoprolol; Midazolam; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenotype; Reference Values; Theophylline

2003