caffeine and 1-methylxanthine

caffeine has been researched along with 1-methylxanthine in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (11.54)	18.7374
1990's	18 (34.62)	18.2507
2000's	17 (32.69)	29.6817
2010's	10 (19.23)	24.3611
2020's	1 (1.92)	2.80

Authors

Authors	Studies
Daly, JW; Padgett, WL; Shamim, MT; Ukena, D	1
Grahner, B; Lanzner, W; Müller, CE; Winiwarter, S	1
Ebihara, A; Hashiguchi, M	1
Kiss, T; Osipenko, ON	1
Kalow, W; Tang, BK	1
Iriah, J; Kadar, D; Kalow, W; Qian, L; Tang, BK; Yip, J	1
Beitins, IZ; Kilbane, AJ; Manis, M; Silbart, LK; Weber, WW	1
Butler, MA; Kadlubar, FF; Lang, NP; Massengill, JP; Talaska, G; Teitel, CH	1
Griener, JC; Morris, ME; Msall, ME	1
Hildebrand, M; Seifert, W	1
Lorenzo, B; Reidenberg, MM	1
Fell, AF; Hudson, SA; Rankin, RB	1
Campbell, ME; Kalow, W; Spielberg, SP	1
Bresnick, E; McQuilkin, SH; Nierenberg, DW	1
Cribb, AE; Gillespie, CT; Isbrucker, R; Levatte, T; Renton, KW; Tsui, B	1
Gee, RL; Kloth, MT; Messing, EM; Swaminathan, S	1
Galteau, MM; Gueguen, R; Pontes, ZB; Siest, G; Vincent-Viry, M	1
Bell, DA; Brubaker, LH; Butler, MA; Kadlubar, FF; Lucier, GW; Stephens, EA; Taylor, JA; Wiest, J	1
Arvela, P; Klebovich, I; Pelkonen, O	1
Bechtel, PR; Bechtel, YC; Bonaiti-Pellie, C; Magnette, J; Poisson, N	1
Birkett, DJ; Day, RO; Lillywhite, KJ; Miners, JO; Valente, L	1
Bernal, ML; Fanlo, A; Juste, JL; Lanuza, J; Mayayo, E; Sáenz, MA; Sinués, B	1
Banerjee, K; Lang, N; Leyland-Jones, B; Massengill, J; Nowell, S; Wong, P	1
Boobis, AR; Edwards, RJ; Murray, BP; Murray, S; Odupitan, AO	1
Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT	1
Cao, XM; Lin, SS; Lu, JF; Yi, T; Zhuo, HT	1
Barrett, E; Coggins, M; Fasy, E; Jahn, L; Kaul, S; Lindner, J; Rattigan, S	1
Crews, HM; Olivier, L; Wilson, LA	1
Cui, X; Guo, R; Li, C; Wang, B; Xu, Z	1
Abraham, K; Bauer, S; Brockmöller, J; Geusau, A; Helge, H; Tosun, Y	1
Borlak, J; Cascorbi, I; Erb, K; Fuhr, U; Hermann, R; Illauer, M; Jetter, A; Kinzig-Schippers, M; Smith, G; Sörgel, F; Wolf, H	1
Cihlar, T; Haefeli, WE; Lindenmaier, H; Rengelshausen, J; Walter-Sack, I; Weiss, J	1
Blaszkewicz, M; Bolt, HM; Dannappel, D; Golka, K; Selinski, S	1
Li, J; Peng, XQ; Xu, JP; Zhang, J	1
Brüning, T; John, A; Rihs, HP; Scherenberg, M; Seidel, A	1
Brøsen, K; Damkier, P; Grandjean, P; Halling, J; Nielsen, F; Petersen, MS; Weihe, P	1
Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A	1
Burhenne, J; Göggelmann, C; Haefeli, WE; Mikus, G; Rengelshausen, J; Riedel, KD; Walter-Sack, I	1
Fuhr, U; Jetter, A; Kinzig, M; Rodamer, M; Sörgel, F; Tomalik-Scharte, D	1
Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Summers, R; Yu, CL	1
Ashida, H; Hashimoto, T; Kanazawa, K; Nakabayashi, H; Nishiumi, S	1
Srinivas, NR	1
Aklillu, E; Carrillo, JA; Djordjevic, N; Fukasawa, T; Gervasini, G; Jankovic, S; Suda, A; Ueda, N	1
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Karlsson, S; Roh, HK; Ueda, N	1
Kamataki, T; Kimura, M; Kiyotani, K; Nakagawa, K; Shimizu, M; Yamazaki, H	1
Fan, XR; Li, XY; Li, YF; Li, YP; Liu, YN; Yang, M; Yao, XC; Yin, YM; Yuan, M; Zhu, JB	1
Borsotti, A; Castiglioni, S; Gracia-Lor, E; Senta, I; Zuccato, E	1
Ahluwalia, N; Pao, CI; Pfeiffer, CM; Rybak, ME; Sternberg, MR	1
Kishimoto, I; Kobayashi, K; Murayama, N; Shimizu, M; Yamazaki, H	1
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Makonnen, E	1
Dong, ZB; Liang, YR; Lu, J; Ma, YX; Wu, HS; Wu, XH; Ye, JH; Zheng, XQ	1
Li, X; Ma, C; Ren, X; Xia, T; Zhou, B	1

Trials

3 trial(s) available for caffeine and 1-methylxanthine

Article	Year
Urinary biomarkers for assessing dietary exposure to caffeine. Food additives and contaminants, 2001, Volume: 18, Issue:12 Topics: Adult; Arylamine N-Acetyltransferase; Biomarkers; Caffeine; Cytochrome P-450 CYP1A2; Diet; Female; Humans; Liver; Male; Middle Aged; Phenotype; Theophylline; Time Factors; Uric Acid; Xanthines	2001
Reduction in non-glomerular renal clearance of the caffeine metabolite 1-methylxanthine by probenecid. International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:8 Topics: Adult; Area Under Curve; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Creatinine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Depression, Chemical; Double-Blind Method; Female; Humans; Kidney; Male; Probenecid; Renal Agents; Spectrophotometry, Ultraviolet; Xanthine Oxidase; Xanthines	2007
Cytochrome P450 2A6 phenotyping based on dietary caffeine intake in a Japanese population of non-smokers. Drug metabolism letters, 2012, Jun-01, Volume: 6, Issue:2 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP2A6; Female; Gene Deletion; Genotype; Humans; Japan; Male; Phenotype; Pilot Projects; Theophylline; Uric Acid; Xanthines; Young Adult	2012

Other Studies

49 other study(ies) available for caffeine and 1-methylxanthine

Article	Year
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions. Journal of medicinal chemistry, 1989, Volume: 32, Issue:6 Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines	1989
Synthesis and structure-activity relationships of deazaxanthines: analogs of potent A1- and A2-adenosine receptor antagonists. Journal of medicinal chemistry, 1994, May-13, Volume: 37, Issue:10 Topics: Animals; Brain; In Vitro Techniques; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Xanthines	1994
Acetylation polymorphism of caffeine in a Japanese population. Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:3 Topics: Acetylation; Adult; Caffeine; Humans; Japan; Male; Metabolism; Phenotype; Polymorphism, Genetic; Uracil; Xanthines	1992
Neurohypophysial peptides selectively depressed high voltage-activated Ca-current in snail neurons. Neuroscience letters, 1990, Nov-27, Volume: 120, Issue:1 Topics: Animals; Barium; Caffeine; Calcium Channels; Ganglia; Helix, Snails; In Vitro Techniques; Lypressin; Membrane Potentials; Neurons; Oxytocin; Phosphodiesterase Inhibitors; Theophylline; Xanthines	1990
Caffeine as a metabolic probe: exploration of the enzyme-inducing effect of cigarette smoking. Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:1 Topics: Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Liver; Nicotiana; Oxidoreductases; Plants, Toxic; Smoking; Uric Acid; Xanthines	1991
Caffeine as a metabolic probe: validation of its use for acetylator phenotyping. Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:6 Topics: Acetylation; Acetyltransferases; Adult; Caffeine; Humans; Phenotype; Polymorphism, Genetic; Sulfamethazine; Time Factors; Uracil; Uric Acid; Xanthines	1991
Human N-acetylation genotype determination with urinary caffeine metabolites. Clinical pharmacology and therapeutics, 1990, Volume: 47, Issue:4 Topics: Acetylation; Caffeine; Chromatography, High Pressure Liquid; Gene Frequency; Genetics, Population; Genotype; Humans; Nitrogen; Pedigree; Phenotype; Theophylline; Time Factors; Uracil; Uric Acid; Xanthines	1990
Determination of carcinogenic arylamine N-oxidation phenotype in humans by analysis of caffeine urinary metabolites. Progress in clinical and biological research, 1990, Volume: 340B Topics: Acetylation; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Cytochrome P-450 Enzyme System; Disease Susceptibility; Humans; Isoenzymes; Oxidation-Reduction; Phenotype; Theophylline; Uracil; Urinary Bladder Neoplasms; Xanthines	1990
N-acetylator variability in Down's syndrome: characterization with caffeine. Clinical pharmacology and therapeutics, 1989, Volume: 46, Issue:3 Topics: Acetylation; Adolescent; Adult; Caffeine; Child; Chromatography, High Pressure Liquid; Down Syndrome; Female; Humans; Male; Middle Aged; Phenotype; Uracil; Xanthines	1989
Determination of acetylator phenotype in Caucasians with caffeine. European journal of clinical pharmacology, 1989, Volume: 37, Issue:5 Topics: Acetylation; Adolescent; Adult; Aged; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Sex Factors; Smoking; Uracil; White People; Xanthines	1989
Potential artifacts in the use of caffeine to determine acetylation phenotype. British journal of clinical pharmacology, 1989, Volume: 28, Issue:2 Topics: Acetylation; Caffeine; False Positive Reactions; Humans; Phenotype; Time Factors; Uracil; Xanthines	1989
Caffeine as a potential indicator for acetylator status. Journal of clinical pharmacy and therapeutics, 1987, Volume: 12, Issue:1 Topics: Acetylation; Acetyltransferases; Adolescent; Adult; Caffeine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenotype; Sulfamethazine; Xanthines	1987
A urinary metabolite ratio that reflects systemic caffeine clearance. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:2 Topics: Adult; Age Factors; Asian People; Caffeine; Child; Child, Preschool; Contraceptives, Oral; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Smoking; Time Factors; Uracil; Uric Acid; White People; Xanthines	1987
Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1995, Volume: 4, Issue:2 Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Female; Genetic Variation; Humans; Male; Middle Aged; Oxidoreductases; Phenotype; Spectrophotometry, Ultraviolet; Theophylline; Time Factors; Uracil; Xanthines	1995
Acetylator phenotyping: the urinary caffeine metabolite ratio in slow acetylators correlates with a marker of systemic NAT1 activity. Pharmacogenetics, 1994, Volume: 4, Issue:3 Topics: 4-Aminobenzoic Acid; Acetylation; Adult; Arylamine N-Acetyltransferase; Biomarkers; Caffeine; Female; Humans; Isoenzymes; Kinetics; Leukocytes, Mononuclear; Male; Middle Aged; Phenotype; Substrate Specificity; Uracil; Xanthines	1994
Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells. Carcinogenesis, 1994, Volume: 15, Issue:12 Topics: Acetylation; Adult; Alleles; Amines; Arylamine N-Acetyltransferase; Biomarkers; Caffeine; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; DNA, Complementary; Epithelial Cells; Epithelium; Female; Gene Expression; Genetic Predisposition to Disease; Humans; Male; Microsomes, Liver; Oxidoreductases; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Risk Factors; Uracil; Ureter; Urinary Bladder Neoplasms; Xanthines	1994
Segregation analyses of four urinary caffeine metabolite ratios implicated in the determination of human acetylation phenotypes. Genetic epidemiology, 1994, Volume: 11, Issue:2 Topics: Acetylation; Adolescent; Adult; Alleles; Arylamine N-Acetyltransferase; Caffeine; Child; Chromatography, High Pressure Liquid; Family; Female; Gene Frequency; Genes, Recessive; Humans; Male; Middle Aged; Models, Genetic; Models, Statistical; Phenotype; Polymorphism, Genetic; Theophylline; Uracil; Uric Acid; Xanthines	1994
Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans. Carcinogenesis, 1993, Volume: 14, Issue:8 Topics: Acetylation; Alleles; Amino Acid Sequence; Arylamine N-Acetyltransferase; Base Sequence; Black People; Caffeine; Genotype; Humans; Molecular Sequence Data; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Sequence Homology, Amino Acid; United States; Uracil; Xanthines	1993
HPLC method for rapid determination of acetylator phenotype by measuring urinary caffeine metabolites. Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:10 Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Phenotype; Reproducibility of Results; Uracil; Xanthines	1993
A population and family study of N-acetyltransferase using caffeine urinary metabolites. Clinical pharmacology and therapeutics, 1993, Volume: 54, Issue:2 Topics: Acetylation; Arylamine N-Acetyltransferase; Caffeine; Family; Heterozygote; Humans; Models, Statistical; Time Factors; Uracil; Xanthines	1993
1-Methylxanthine derived from caffeine as a pharmacodynamic probe of oxypurinol effect. British journal of clinical pharmacology, 1997, Volume: 43, Issue:2 Topics: Adult; Caffeine; Female; Humans; Male; Molecular Probes; Oxypurinol; Uric Acid; Xanthines	1997
Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenicity and urine flow. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:2 Topics: Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Environmental Exposure; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mutagens; Rheology; Smoking; Theophylline; Time Factors; Uracil; Uric Acid; Urination; Xanthines	1999
Validity of an ELISA for N-acetyltransferase-2 (NAT2) phenotyping. Journal of immunological methods, 2001, May-01, Volume: 251, Issue:1-2 Topics: Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Genotype; Humans; Phenotype; Uracil; Xanthines	2001
Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline. Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:3 Topics: Acetaminophen; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Caffeine; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inhibitory Concentration 50; Kinetics; Magnesium Chloride; Microsomes, Liver; Mixed Function Oxygenases; Models, Chemical; Pentoxifylline; Phenacetin; Protein Binding; Serum Albumin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Theophylline; Time Factors; Tromethamine; Xanthines	2001
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities]. Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:11 Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines	1997
[HPLC determination of five caffeine metabolites]. Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:8 Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Theophylline; Uracil; Uric Acid; Xanthines	1997
Physiologic hyperinsulinemia enhances human skeletal muscle perfusion by capillary recruitment. Diabetes, 2001, Volume: 50, Issue:12 Topics: Adult; Albumins; Blood Flow Velocity; Blood Glucose; Blood Volume; Brachial Artery; Caffeine; Capillaries; Female; Glucose; Humans; Insulin; Lactic Acid; Male; Muscle, Skeletal; Oxygen Consumption; Theophylline; Xanthines	2001
Relationship between metabolic phenotype of N-acetylation and bladder cancer. Chinese medical journal, 2000, Volume: 113, Issue:4 Topics: Acetylation; Adult; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Uracil; Urinary Bladder Neoplasms; Xanthines	2000
Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction. Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:2 Topics: Adult; Breath Tests; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Enzyme Induction; Female; Humans; Liver; Male; Methylation; Polychlorinated Dibenzodioxins; Smoking; Teratogens; Theophylline; Uracil; Uric Acid; Xanthines	2002
Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure. European journal of clinical pharmacology, 2004, Volume: 60, Issue:1 Topics: Acetylation; Administration, Oral; Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Diet; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Spectrometry, Mass, Electrospray Ionization; Time Factors; Uracil; Uric Acid; Xanthines	2004
Inhibition of the human organic anion transporter 1 by the caffeine metabolite 1-methylxanthine. Biochemical and biophysical research communications, 2004, Jul-16, Volume: 320, Issue:1 Topics: Animals; Caffeine; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Fluoresceins; Humans; Organic Anion Transporters; Theophylline; Xanthines	2004
Re-investigation of the concordance of human NAT2 phenotypes and genotypes. Archives of toxicology, 2005, Volume: 79, Issue:4 Topics: Acetylation; Alleles; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Genotype; Humans; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Uracil; Xanthines	2005
[Determination of the activity of cytochrome P-450 CYP2A6 by HPLC method with caffeine as metabolizing probe]. Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:3 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Female; Humans; Male; Mixed Function Oxygenases; Theophylline; Uracil; Uric Acid; Xanthines	2006
Concordance between the deduced acetylation status generated by high-speed: real-time PCR based NAT2 genotyping of seven single nucleotide polymorphisms and human NAT2 phenotypes determined by a caffeine assay. Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 376, Issue:1-2 Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Genotype; Humans; Male; Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Uracil; Uric Acid; White People; Xanthines	2007
Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls. European journal of clinical pharmacology, 2006, Volume: 62, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Biometry; Caffeine; Cohort Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Female; Genotype; Humans; Male; Methylation; Middle Aged; Polychlorinated Biphenyls; Sex Factors; Smoking; Uracil; Uric Acid; Xanthines	2006
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios. Biomedical chromatography : BMC, 2007, Volume: 21, Issue:2 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines	2007
Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected? European journal of clinical pharmacology, 2009, Volume: 65, Issue:4 Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Humans; Male; Phenotype; Time Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines	2009
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5. Journal of bacteriology, 2009, Volume: 191, Issue:14 Topics: Caffeine; Gene Expression; Metabolic Networks and Pathways; Pseudomonas putida; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines	2009
Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes. BioFactors (Oxford, England), 2008, Volume: 34, Issue:4 Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Biological Transport; Caffeine; Cell Differentiation; Glucose; Insulin; Lipid Metabolism; Mice; Theophylline; Uracil; Uric Acid; Xanthines	2008
Is 1-methylxanthine an ideal model substrate for establishing the renal tubular transport of organic ions? International journal of clinical pharmacology and therapeutics, 2010, Volume: 48, Issue:2 Topics: Biological Transport; Caffeine; Humans; Kidney Tubules; Organic Anion Transporters; Xanthines	2010
N-Acetyltransferase-2 (NAT2) gene polymorphisms and enzyme activity in Serbs: unprecedented high prevalence of rapid acetylators in a White population. Journal of clinical pharmacology, 2011, Volume: 51, Issue:7 Topics: Acetylation; Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Female; Genetic Association Studies; Haplotypes; Humans; Isoenzymes; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Serbia; Uracil; Uric Acid; White People; Xanthines; Young Adult	2011
Comparison of N-acetyltransferase-2 enzyme genotype-phenotype and xanthine oxidase enzyme activity between Swedes and Koreans. Journal of clinical pharmacology, 2012, Volume: 52, Issue:10 Topics: Arylamine N-Acetyltransferase; Asian People; Caffeine; Contraceptives, Oral; Genotype; Humans; Phenotype; Polymorphism, Single Nucleotide; Sex Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines	2012
[Effect of Tibetan medicine zuotai on the activity, protein and mRNA expression of CYP1A2 and NAT2]. Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:2 Topics: Administration, Oral; Animals; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Male; Medicine, Tibetan Traditional; Rats; Rats, Sprague-Dawley; RNA, Messenger; Theophylline; Uracil; Uric Acid; Xanthines	2014
Wastewater analysis to monitor use of caffeine and nicotine and evaluation of their metabolites as biomarkers for population size assessment. Water research, 2015, May-01, Volume: 74 Topics: Biomarkers; Caffeine; Chromatography, Liquid; Cities; Humans; Italy; Nicotine; Population Density; Smoking; Tandem Mass Spectrometry; Wastewater; Xanthines	2015
Urine excretion of caffeine and select caffeine metabolites is common in the U.S. population and associated with caffeine intake. The Journal of nutrition, 2015, Volume: 145, Issue:4 Topics: Adolescent; Adult; Biomarkers; Black or African American; Caffeine; Child; Chromatography, Liquid; Cross-Sectional Studies; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nutrition Surveys; Tandem Mass Spectrometry; Theophylline; Uracil; Uric Acid; White People; Xanthines; Young Adult	2015
Cytochrome P450 2A6 Phenotyping Using Dietary Caffeine Salivary Metabolite Ratios and Genotyping Using Blood on Storage Cards in Non-smoking Japanese Volunteers. Drug metabolism letters, 2017, Volume: 10, Issue:4 Topics: Adult; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Diet; Female; Genotyping Techniques; Healthy Volunteers; Humans; Male; Middle Aged; Multiplex Polymerase Chain Reaction; Phenotype; Real-Time Polymerase Chain Reaction; Saliva; Specimen Handling; Tea; Uric Acid; Xanthines	2017
N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians. European journal of clinical pharmacology, 2018, Volume: 74, Issue:7 Topics: Adult; Arylamine N-Acetyltransferase; Black People; Caffeine; Ethiopia; Female; Gene-Environment Interaction; Genotype; Humans; Male; Phenotype; Polymorphism, Single Nucleotide; Sweden; Uracil; Uric Acid; Xanthines	2018
Different Catabolism Pathways Triggered by Various Methylxanthines in Caffeine-Tolerant Bacterium Journal of microbiology and biotechnology, 2018, Jul-28, Volume: 28, Issue:7 Topics: Biodegradation, Environmental; Caffeine; Drug Tolerance; Gardens; Metabolic Networks and Pathways; Pseudomonas putida; Soil; Soil Microbiology; Substrate Specificity; Tea; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines	2018
LC-MS/MS-based metabolomic analysis of caffeine-degrading fungus Aspergillus sydowii during tea fermentation. Journal of food science, 2020, Volume: 85, Issue:2 Topics: Aspergillus; Caffeine; Chromatography, High Pressure Liquid; Fermentation; Flavonoids; Metabolomics; Plant Leaves; Tandem Mass Spectrometry; Tea; Xanthines	2020