Compounds > caffeic acid phenethyl ester
Page last updated: 2024-09-02

caffeic acid phenethyl ester and tamoxifen

caffeic acid phenethyl ester has been researched along with tamoxifen in 5 studies

Compound Research Comparison

Studies
(caffeic acid phenethyl ester)		Trials
(caffeic acid phenethyl ester)		Recent Studies (post-2010)
(caffeic acid phenethyl ester)		Studies
(tamoxifen)		Trials
(tamoxifen)		Recent Studies (post-2010) (tamoxifen)
840146920,6302,2276,256

Protein Interaction Comparison

ProteinTaxonomycaffeic acid phenethyl ester (IC50)tamoxifen (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.46
Serine/threonine-protein kinase D3Homo sapiens (human)1
Bile salt export pumpHomo sapiens (human)10
Epidermal growth factor receptorHomo sapiens (human)3.553
Estrogen receptorHomo sapiens (human)0.9266
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)2.949
Protein kinase C gamma typeHomo sapiens (human)1
Protein kinase C beta typeHomo sapiens (human)1
Tyrosine-protein kinase LckHomo sapiens (human)8.033
Tyrosine-protein kinase FynHomo sapiens (human)1.195
Progesterone receptorHomo sapiens (human)0.1288
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.472
Muscarinic acetylcholine receptor M2Homo sapiens (human)7.793
Muscarinic acetylcholine receptor M4Homo sapiens (human)4.817
ATP-dependent translocase ABCB1Homo sapiens (human)6.4
Muscarinic acetylcholine receptor M5Homo sapiens (human)2.585
Alpha-2A adrenergic receptorHomo sapiens (human)1.935
Adenosine receptor A3Homo sapiens (human)3.701
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.829
Steroid hormone receptor ERR1Homo sapiens (human)0.2
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.967
Beta-3 adrenergic receptorHomo sapiens (human)7.703
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)3.701
Protein kinase C alpha typeHomo sapiens (human)1
Alpha-2B adrenergic receptorHomo sapiens (human)3.518
Muscarinic acetylcholine receptor M3Homo sapiens (human)2.974
Substance-K receptorHomo sapiens (human)3.67
D(1A) dopamine receptorHomo sapiens (human)8.502
Prostaglandin G/H synthase 1Homo sapiens (human)4.391
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.472
Thromboxane-A synthase Homo sapiens (human)0.916
Protein kinase C eta typeHomo sapiens (human)1
Histamine H2 receptorHomo sapiens (human)9.396
Alpha-1D adrenergic receptorHomo sapiens (human)4.982
5-hydroxytryptamine receptor 2AHomo sapiens (human)4.801
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.46
Adenosine receptor A2aHomo sapiens (human)7.099
Sodium-dependent serotonin transporterHomo sapiens (human)2.334
D(3) dopamine receptorHomo sapiens (human)1.072
5-hydroxytryptamine receptor 2BHomo sapiens (human)2.084
Protein kinase C iota typeHomo sapiens (human)1
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)3.701
5-hydroxytryptamine receptor 6Homo sapiens (human)2.679
Estrogen-related receptor gammaHomo sapiens (human)0.0622
Sodium-dependent dopamine transporter Homo sapiens (human)1.841
Protein kinase C epsilon typeHomo sapiens (human)1
Protein kinase C theta typeHomo sapiens (human)1
Protein kinase C zeta typeHomo sapiens (human)1
Protein kinase C delta typeHomo sapiens (human)1
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.2759
Platelet-activating factor acetylhydrolaseHomo sapiens (human)0.904
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)0.012
Serine/threonine-protein kinase D1Homo sapiens (human)1
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)0.967
Estrogen receptor betaHomo sapiens (human)0.7809
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.021
7-dehydrocholesterol reductaseHomo sapiens (human)0.012

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
Bhimani, RS; Frenkel, K; Grunberger, D; Troll, W1
Abdel-Naim, AB; Albukhari, AA; El-Beshbishy, HA; Gashlan, HM; Nagy, AA1
Abdelazim, SA; Darwish, HA; Elbaz, EM; Motawi, TK; Shouman, SA2

Other Studies

5 other study(ies) available for caffeic acid phenethyl ester and tamoxifen

ArticleYear
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Inhibition of oxidative stress in HeLa cells by chemopreventive agents.
    Cancer research, 1993, Oct-01, Volume: 53, Issue:19

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Anticarcinogenic Agents; Antineoplastic Agents; Caffeic Acids; Catechin; Deoxyguanosine; Diterpenes; DNA, Neoplasm; HeLa Cells; Humans; Hydrogen Peroxide; Hydrolyzable Tannins; Oxidation-Reduction; Phenylethyl Alcohol; Tamoxifen; Tannins; Tetradecanoylphorbol Acetate; Thymidine

1993
Caffeic acid phenethyl ester protects against tamoxifen-induced hepatotoxicity in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:7

    Topics: Animals; Antineoplastic Agents, Hormonal; Antioxidants; Caffeic Acids; Chemical and Drug Induced Liver Injury; Female; Glutathione; Lipid Peroxidation; Liver; Liver Function Tests; Neutrophils; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tamoxifen; Tumor Necrosis Factor-alpha; Xanthine Oxidase

2009
Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Beclin-1; Breast Neoplasms; Caffeic Acids; Female; Humans; MCF-7 Cells; Membrane Proteins; Microtubule-Associated Proteins; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2; Tamoxifen

2016
Could Caffeic Acid Phenethyl Ester Expand the Antitumor Effect of Tamoxifen in Breast Carcinoma?
    Nutrition and cancer, 2016, Volume: 68, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Caffeic Acids; Carcinoma, Ehrlich Tumor; Caspase 3; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Phenylethyl Alcohol; Proteins; Tamoxifen; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2016