caffeic acid phenethyl ester has been researched along with phenylethyl alcohol in 730 studies
Studies (caffeic acid phenethyl ester) | Trials (caffeic acid phenethyl ester) | Recent Studies (post-2010) (caffeic acid phenethyl ester) | Studies (phenylethyl alcohol) | Trials (phenylethyl alcohol) | Recent Studies (post-2010) (phenylethyl alcohol) |
---|---|---|---|---|---|
840 | 1 | 469 | 2,696 | 63 | 1,615 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (0.14) | 18.7374 |
1990's | 24 (3.29) | 18.2507 |
2000's | 257 (35.21) | 29.6817 |
2010's | 366 (50.14) | 24.3611 |
2020's | 82 (11.23) | 2.80 |
Authors | Studies |
---|---|
Choi, HJ; Chung, TW; Ha, KT; Jeong, HS; Kim, CH; Lee, JY | 1 |
Fisher, PB; Grunberger, D; Guarini, L; Lin, J; Su, ZZ; Zucker, S | 1 |
Fisher, PB; Grunberger, D; Su, ZZ | 1 |
Banerjee, R; Caldwell, M; Efros, L; Eisinger, K; Estevez, V; Grunberger, D; Nakanishi, K; Oltz, EM | 1 |
Burke, TR; Carothers, AM; Driscoll, J; Fesen, MR; Grunberger, D; Kohn, K; Mazumder, A; Pommier, Y; Wang, J | 1 |
Fisher, PB; Grunberger, D; Lin, J; Su, ZZ | 1 |
Fesen, MR; Hiroguchi, S; Kohn, KW; Leteurtre, F; Pommier, Y; Yung, J | 1 |
Korshunova, GA; Mirzoeva, OK; Pushkareva, MA; Sud'ina, GF; Sumbatian, NV; Varfolomeev, SD | 1 |
Barrett, JC; Carothers, AM; Chiao, C; Grunberger, D; Preston, GA; Solomon, G | 1 |
Bhimani, R; Conney, AH; Ferraro, T; Frenkel, K; Grunberger, D; Huang, MT; Wei, H; Ye, J; Zadunaisky, JA | 1 |
Korshunova, GA; Mirzoeva, OK; Pushkareva, MA; Sud'ina, GF; Sumbatyan, NV; Varfolomeev, SD | 1 |
Bhimani, RS; Frenkel, K; Grunberger, D; Troll, W | 1 |
Conney, AH; Frenkel, K; Grunberger, D; Han, J; Huang, MT; Ma, W; Xie, JG; Yen, P | 1 |
Aggarwal, BB; Burke, TR; Grunberger, D; Natarajan, K; Singh, S | 1 |
Grunberger, D; Prystowsky, JH; Xue, GZ; Zheng, ZS | 1 |
Calder, PC; Knox, KA; Mirzoeva, OK; Yaqoob, P | 1 |
Chen, JH; Chin, CK; Ho, CT; Huang, MT; Shao, Y | 1 |
Carothers, AM; Grunberger, D; Jaiswal, AK; Mucha, J; Venugopal, R | 1 |
Calder, PC; Mirzoeva, OK | 1 |
Chen, J; Hong, H; Mazumder, A; Milne, GW; Neamati, N; Nicklaus, MC; Pommier, Y; Sunder, S | 1 |
Burke, TR; Mazumder, A; Neamati, N; Pommier, Y; Sunder, S; Zhao, H | 1 |
Bouillon, R; Courtois, SJ; Degreef, H; Garmyn, M; Segaert, S | 1 |
Carothers, AM; Dannenberg, AJ; Grunberger, D; Koboldt, C; Masferrer, JL; Mestre, JR; Michaluart, P; Sacks, PG; Subbaramaiah, K; Tanabe, T; Zweifel, BS | 1 |
Akyol, O; Aydin, E; Aydinç, M; Gültek, A; Gürsoy, MH; Karaman, A; Koltuksuz, U; Ozen, S; Uz, E | 1 |
Farrow, S; Holloway, KA; Howells, L; Kaptein, A; Manson, MM; Munks, RJ; Plummer, SM | 1 |
Akyol, O; Ciralik, H; Ilhan, A; Koltuksuz, U; Ozen, S; Uz, E | 1 |
Dworniczak, S; Pogorzelska, T; Rajca, M; Scheller, S; Shani, J | 1 |
Burke, TR; Chrousos, GP; Mitsiades, N; Orban, Z; Tsokos, M | 1 |
Bertagnolli, ME; Bertagnolli, MM; Carothers, AM; Weyant, MJ | 1 |
Chen, WK; Lee, YJ; Liao, PH; Yang, CY | 1 |
Chang, CC; Grunberger, D; Kang, KS; Na, HK; Trosko, JE; Wilson, MR | 1 |
Li, D; Mehta, JL; Romeo, F; Saldeen, T | 1 |
Lewis, BA; Lobkowsky, EB; Son, S | 1 |
Akyol, O; Irmak, MK; Karaman, A; Koltuksuz, U; Ozyurt, H; Uz, E; Var, A | 1 |
Chen, YJ; Shiao, MS; Wang, SY | 1 |
Dong, Z; Kaji, A; Ma, W; Miyamoto, K; Nomura, M | 1 |
Akyol, O; Irmak, MK; Karaman, A; Koltuksuz, U; Kutlu, NO; Ozyurt, H; Yağmurca, M | 1 |
Hishikawa, K; Nakaki, T | 1 |
Akyol, O; Aydin, NE; Cetin, S; Gürbüz, N; Karaman, A; Koltuksuz, U; Kutlu, R; Mutuş, HM; Ozyurt, H | 1 |
Bagnara, GP; Bonsi, L; Fiorentini, D; Hakim, G; Landi, L; Maraldi, T | 1 |
Huleihel, M; Ishano, V | 1 |
Chen, YJ; Hsu, ML; Shiao, MS; Tsai, TH; Wang, SY | 1 |
Fitzpatrick, LR; Le, T; Wang, J | 1 |
Hur, GM; Jin, C; Kim, YM; Lee, JY; Lee, YS; Park, EH; Ryu, YS; Song, YS | 1 |
Akyol, O; Irmak, MK; Ozyurt, H; Söğüt, S | 1 |
Aydin, E; Borazan, M; Cekiç, O; Cihan Dağloğlu, M; Dağlioğlu, K; Gültek, A; Totan, Y | 1 |
Calabrese, V; Foresti, R; Giuffrida Stella, AM; Green, CJ; Motterlini, R; Scapagnini, G | 1 |
Fahlman, CS; Haddad, JJ | 1 |
Borrelli, F; Capasso, F; Ialenti, A; Ianaro, A; Maffia, P; Pinto, A; Pisano, B | 1 |
Banskota, AH; Kadota, S; Matsushige, K; Midorikawa, K; Tezuka, Y; Usia, T | 1 |
Banskota, AH; Kadota, S; Nagaoka, T; Saiki, I; Tezuka, Y | 1 |
Bozaran, M; Doganay, S; Er, H; Evereklioglu, C; Ozerol, E; Turkoz, Y | 1 |
Chen, F; Huang, C; Lu, B; Medan, D; Rojanasakul, Y; Shi, X; Toledo, D; Wang, L | 1 |
Jin, C; Jung, KJ; Park, EH; Song, YS | 1 |
Akyol, O; Güleç, M; Ozyurt, H; Sahin, S; Söğüt, S; Uz, E; Var, A | 1 |
Borrelli, F; Ligresti, A; Longo, R; Rossi, A; Russo, A; Sautebin, L | 1 |
Ayan, I; Bora, A; Elmali, N; Germen, B; Mizrak, B; Türköz, Y | 1 |
Longo, R; Russo, A; Vanella, A | 1 |
Borrelli, F; Longo, R; Rossi, A; Russo, A; Sautebin, L | 1 |
Borrelli, F; Capasso, F; Di Carlo, G; Izzo, AA; Maffia, P; Maiello, FM; Mascolo, N; Russo, A | 1 |
Ceschel, GC; Lombardi Borgia, S; Maffei, P; Ronchi, C; Sforzini, A; Yasin, A | 1 |
Borrelli, F; Capasso, F; Ialenti, A; Ianaro, A; Maffia, P; Pinto, L; Russo, A | 1 |
Buhay, S; Helwer, G; Litchie, B; Thomas, S; Werner, JP; Zahradka, P | 1 |
Alam, J; Balogun, E; Foresti, R; Gong, P; Green, CJ; Hoque, M; Killeen, E; Motterlini, R | 1 |
Banskota, AH; Kadota, S; Matsushige, K; Midorikawa, K; Nagaoka, T; Tezuka, Y | 1 |
Krings, G; Lopes-Virella, MF; Vielma, SA | 1 |
Borrelli, F; Capasso, R; Cicala, C; Iorio, C; Mascolo, N; Morello, S | 1 |
Banskota, AH; Harimaya, Y; Kadota, S; Koizumi, K; Nagaoka, T; Saiki, I; Tezuka, Y | 1 |
Liang, CL; Pan, XH; Pang, RQ; Zhao, B; Zhao, J; Zhao, WX | 1 |
Borrelli, F; Cardile, V; Gentile, B; Panico, A; Russo, A | 1 |
Bockaert, J; Briant, L; Courseau, AS; de Bock, F; Lerner-Natoli, M; Montpied, P; Niel, G; Rondouin, G | 1 |
Calikoglu, I; Calikoglu, M; Coskun, B; Ercan, B; Gul, A; Kanik, A; Sucu, N; Tamer, L | 1 |
Erdogan, H; Fadillioglu, E; Gozukara, ME; Gulec, M; Irmak, MK; Ozer, M; Sogut, S; Yagmurca, M | 1 |
Huuskonen, J; Kyrylenko, S; Pihlaja, R; Salminen, A; Suuronen, T | 1 |
Amodio, R; Cacchio, M; De Ruvo, C; Di Matteo, V; Di Santo, A; Esposito, E; Lorenzet, R; Martelli, N; Poggi, A; Rotilio, D; Sacchetti, A | 1 |
Calzado, MA; Fiebich, BL; Macho, A; Márquez, N; Muñoz, E; Sancho, R | 1 |
Hishikawa, K; Nakaki, T; Shimizu, N; Takayanagi, A; Watabe, M | 1 |
Chu, CY; Kuo, HC; Lee, YJ; Lin, WC; Tseng, TH; Wang, CJ | 1 |
Chen, CN; Lin, JK; Wu, CL | 2 |
Blijlevens, NM; de Witte, TJ; Donnelly, JP; M'Rabet, L; Marteijn, J; Timal, S; van't Land, B | 1 |
Akyol, O; Armutcu, F; Gulec, M; Gurel, A; Kutlu, NO; Ozyurt, H; Sahin, S; Sogut, S | 1 |
Akyol, O; Armutçu, F; Iraz, M; Kart, L; Ozen, S; Ozyurt, H; Söğüt, S; Temel, I; Uzun, A; Yildirim, Z | 1 |
Chen, YJ; Chen, YY; Hsu, ML; Liao, HF; Liao, HJ; Liu, JJ; Shiao, MS; Shieh, CJ; Shieh, HJ | 1 |
Hitsuda, Y; Igishi, T; Kodani, M; Matsumoto, S; Nakanishi, H; Shigeoka, Y; Shimizu, E; Yasuda, K | 1 |
Arce-Popoca, E; Carrasco-Legleu, CE; Fattel-Fazenda, S; Márquez-Rosado, L; Pérez-Carreón, JI; Villa-Treviño, S | 1 |
Douglas, SD; Guo, CJ; Ho, WZ; Li, Y; Qi, XX; Song, L; Zhang, T | 1 |
Clarençon, D; Linard, C; Marquette, C; Mathé, D; Mathieu, J; Pennequin, A | 1 |
Armutcu, F; Babucçu, O; Gürel, A; Hoşnuter, M; Işikdemir, A; Kargi, E | 1 |
Chung, KS; Hoe, KL; Jang, YJ; Kim, DU; Maeng, PJ; Oh, GT; Park, SK; Ryoo, SW; Won, M; Yoo, HS | 1 |
Chung, SJ; Chung, ST; Eom, JH; Kim, HS; Kim, KA; Lee, JK; Oh, HY; Paik, SY; Park, JH | 1 |
Huang, MH; Lin, MW; Wu, SN; Yang, SR | 1 |
Brudzynski, K; Carlone, R | 1 |
Borazan, M; Cigremis, Y; Er, H; Mizrak, B; Parlakpinar, H; Turkoz, Y; Yilmaz, H | 1 |
Akyol, O; Armutcu, F; Gurel, A; Ilhan, A; Iraz, M; Oztas, E | 1 |
Coffey, R; Fitzpatrick, JM; McEleny, K; Morrissey, C; Watson, RW | 1 |
Acet, A; Ozer, MK; Parlakpinar, H | 1 |
Chen, MF; Chen, WC; Chen, YJ; Keng, PC; Wu, CT | 1 |
Akyol, O; Gulec, M; Iraz, M; Kalcioglu, MT; Kizilay, A; Ozerol, E; Ozturan, O | 1 |
Del Boccio, P; Rotilio, D | 1 |
Colakoglu, N; Kus, I; Ogeturk, M; Pekmez, H; Sarsilmaz, M; Seckin, D | 1 |
Aktaş, S; Calikoğlu, I; Calikoğlu, M; Sucu, N; Tamer, L; Unlü, A | 1 |
Celli, N; Dragani, LK; Mariani, B; Murzilli, S; Rossi, C; Rotilio, D | 1 |
Erdogan, H; Fadillioglu, E; Iraz, M; Songur, A; Ucar, M; Yagmurca, M | 1 |
Farrar, WL; Hodge, DR; Wang, L; Xiao, W; Yang, X; Zhang, X | 1 |
Douglas, SD; Gao, Z; Grinspan, J; Guo, CJ; Ho, WZ; Lai, JP; Riedel, E; Wolf, BA | 1 |
Altuntas, I; Ozcelik, N; Uz, E; Yilmaz, HR; Yucel, N | 1 |
Dodel, RC; Du, Y; Farlow, MR; Hampel, H; Holtzman, DM; Ma, Z; Oertel, W; Wei, X; Yan, C; Zhao, L | 1 |
Atmaca, G; Aydogdu, N; Batcioglu, K; Kaymak, K; Yalcin, O | 1 |
Fujita, T; Hishikawa, K; Nakaki, T | 1 |
Chang, YC; Cho, G; Chung, TW; Kim, CH; Kim, JG; Kim, SH; Ko, JH; Lee, YC; Moon, SK | 1 |
Foresti, R; Green, CJ; Hoque, M; Monti, D; Motterlini, R | 1 |
Celik, O; Cigremis, Y; Hascalik, M; Hascalik, S; Mizrak, B; Turkoz, Y; Yologlu, S | 1 |
Altinyazar, C; Armutcu, F; Gurel, A; Hosnuter, M; Kargi, E; Unalacak, M | 1 |
Acet, A; Bay-Karabulut, A; Parlakpinar, H; Polat, A; Tasdemir, S; Ucar, M; Vardi, N | 1 |
Okutan, H; Ozcelik, N; Uz, E; Yilmaz, HR | 1 |
Chun, KS; Kang, KS; Lee, HJ; Lee, JS; Lee, KW; Surh, YJ | 1 |
Akyol, O; Armutcu, F; Gurel, A; Ilhan, A; Iraz, M | 1 |
Al-Anati, L; Katz, N; Petzinger, E | 1 |
Colakoglu, N; Ilhan, N; Kus, I; Ogeturk, M; Sarsilmaz, M; Zararsiz, I | 1 |
Fujita, T; Iwai, K; Kakino, Y; Kishimoto, N | 1 |
Acet, A; Mizrak, B; Parlakpinar, H; Polat, A; Sahna, E | 1 |
Nishioka, N; Tsuji, T; Yoshizumi, K | 1 |
Acet, A; Ozturk, F; Parlakpinar, H; Vardi, N | 1 |
Shi, XY; Shieh, DB; Wu, SN; Wu, YN; Yang, SR | 1 |
Armagan, A; Caliskan, S; Koylu, H; Koyu, A; Ozguner, F | 1 |
Chou, FP; Kuo, HC; Kuo, WH; Lee, YJ; Lin, WL; Tseng, TH | 1 |
Chang, KW; Chen, CF; Don, MJ; Ho, LK; Hung, PS; Lee, YT; Lo, YS; Shen, YC | 1 |
Ayaz, L; Aytacoglu, B; Bayri, O; Dikmengil, M; Döndaş, A; Ozeren, M; Sucu, N; Tamer, L | 1 |
Acet, A; Eşrefoğlu, M; Gül, M; Parlakpinar, H | 1 |
Mayhan, WG; Miller, DW; Trickler, WJ | 1 |
Cinel, L; Degirmenci, U; Ercil, M; Kanik, A; Koksel, O; Ozdulger, A; Tamer, L; Unlu, S | 1 |
Bianchi, R; Bonomini, F; Buffoli, B; Giugno, L; Rezzani, R | 1 |
Awale, S; Kadota, S; Matsushige, K; Shrestha, SP; Tezuka, Y; Ueda, JY | 1 |
Isik, B; Ozugurlu, F; Ozyurt, B; Ozyurt, H; Sahin, S; Sogut, S; Uz, E; Yilmaz, HR | 1 |
Acet, A; Cigremis, Y; Ozer, MK; Parlakpinar, H; Ucar, M; Vardi, N | 2 |
Chen, CS; Chen, FL; Chou, MY; Ho, CC; Hu, CC; Lin, SS; Lu, GY; Yang, CC | 1 |
Chung, KH; Chung, TW; Gu, YH; Jin, UH; Kang, SK; Kim, CH; Kim, JK; Suh, SJ; Suzuki, I | 1 |
Bastürk, M; Cinel, L; Degirmenci, U; Kanik, A; Kaplan, MB; Koksel, O; Ozdulger, A; Tamer, L | 1 |
Daniel, BM; DeCoster, MA; Wang, G | 1 |
Eckard, J; Frenkel, K; Huang, X; Rossman, TG; Wu, J; Yang, C; Yusuf, R; Zhang, P; Zhang, R | 1 |
Chen, YC; Chih, CL; Huang, SS; Liao, PH; Lin, RH; Lin, SM; Liu, SM; Tsai, SK | 1 |
Armagan, A; Demirel, R; Koyu, A; Oktem, F; Ozguner, F; Uz, E; Vural, H; Yilmaz, R | 1 |
Ayata, A; Koyu, A; Oktem, F; Ozguner, F; Yilmaz, HR | 1 |
Akturk, O; Altuntas, I; Oktem, F; Olgar, S; Ozguner, F; Sulak, O; Yilmaz, HR | 1 |
Oktem, F; Ozgüner, F; Uz, E; Uzar, E; Yilmaz, HR | 1 |
Atik, U; Cinel, L; Değirmenci, U; Kanik, A; Oz, O; Tamer, L; Vatansever, H; Yildirim, O; Yilmaz, A | 1 |
Chiou, SH; Chiu, JH; Lin, YH; Tseng, WS; Wong, TT; Yen, SH | 1 |
Ascione, V; Aviello, G; Borrelli, F; Capasso, F; Capasso, R; Posadas, I | 1 |
Crippen, TL | 1 |
Chung, HJ; Hong, JY; Hwang, HJ; Lee, SK; Min, HY; Park, EJ; Park, HJ | 1 |
Du, R; Du, Y; Farlow, MR; Han, L; Hou, D; Johnstone, BH; Ma, Z; Tan, J; Wei, X; Zhao, L | 1 |
Abdel-Latif, MM; Homasany, BS; Kelleher, D; Sabra, K; Windle, HJ | 1 |
Chen, YJ; Liao, HF; Shiao, MS; Tsai, TH; Wang, SY | 1 |
Akyol, O; Bagci, C; Cagli, K; Cavdar, S; Cengiz, B; Dinckan, H; Gulec, M; Pence, S; Sari, I | 1 |
Min, TS; Park, SH | 1 |
Chih, CL; Huang, SS; Liao, PH; Lin, MJ; Lin, RH; Lin, SM; Liu, SM; Tsai, SK; Yang, CY | 1 |
Bardak, Y; Comlekci, S; Ozguner, F | 1 |
Bas, O; Kilbas, S; Koyuncuoglu, HR; Kucuker, H; Sahin, O; Songur, A; Uz, E; Uzar, E; Yilmaz, HR; Yurekli, VA | 1 |
Chen, MF; Chen, WC; Keng, PC; Liao, SK; Lin, PY; Yang, CT | 1 |
Altinbas, A; Cesur, G; Dogan, A; Kisioglu, AN; Ozaydin, M; Ozguner, F; Vural, H; Yildirim, NG | 1 |
Erdogan, S; Fadillioglu, E; Iraz, M; Tasdemir, S | 1 |
Akpolat, N; Aladag, MA; Cigremis, Y; Ozcan, C; Parlakpinar, H; Sahna, E; Turkoz, Y | 1 |
Chen, H; Costa, M; Eckard, J; Frenkel, K; Huang, X; Wu, J | 1 |
Basić, I; Orsolić, N; Saranović, AB | 1 |
Altuntas, I; Eren, I; Malas, MA; Ramazan Yilmaz, H; Sahin, O; Songur, A; Sulak, O; Uz, E; Yavuz, Y | 1 |
Kus, I; Ozyurt, B; Ozyurt, H; Parlaktas, BS; Pekmez, H; Sarsilmaz, M | 1 |
Akyol, A; Alver, A; Beşir, A; Cay, A; Ertürk, E; Imamoğlu, M; Koşucu, M; Ozen, I; Ulusoy, H; Yuluğ, E | 1 |
Alaybeyoglu, N; Bilen, BT; Celik, M; Gültek, A; Iraz, M; Kilinç, H; Sezgin, N | 1 |
Bowman, PD; Kerwin, SM; Stavchansky, S; Wang, X | 3 |
Akyol, O; Bagci, C; Gulec, M; Ince, H; Kandemir, E | 1 |
Ates, B; Dogru, AK; Dogru, MI; Erdogan, A; Esrefoglu, M; Gul, M; Yilmaz, I; Yurekli, M | 1 |
Dodel, R; Du, Y; Fontanilla, C; Hampel, H; Ma, Z; Noelker, C; Wei, X | 1 |
Gultekin, F; Kilbas, S; Koyuncuoglu, HR; Kutluhan, S; Uz, E; Uzar, E; Yilmaz, HR | 1 |
Chiechio, S; Copani, A; De Petris, L; Gereau, RW; Morales, ME; Nicoletti, F | 1 |
Kuo, HC; Kuo, WH; Lee, YJ; Tseng, TH; Wang, CJ | 1 |
Iraz, M; Koca, K; Ozyurt, B; Ozyurt, H; Sahin, S | 1 |
Buyukbas, S; Cabuk, M; Kanter, M; Ocakci, A | 1 |
Lee, YJ; Tseng, TH | 1 |
Mitchell, BF; Olson, DM; Wilson, RR; Zaragoza, DB | 1 |
Atik, E; Görür, S; Kiper, AN | 1 |
Cheng, KS; Li, CL; Lin, MW; Ting, WH; Wu, AZ; Wu, SN | 1 |
Ayata, A; Oktem, F; Olgar, S; Ozguner, F; Uz, E; Uzare, E; Yilmaz, HR | 1 |
He, Y; Li, Z; Wang, D; Xiang, D; Xie, J; Zhong, Z | 1 |
Fu, T; He, YH; He, YJ; Liu, BH; Qiao, ZY; Xiang, DB | 1 |
Benderitter, M; Grémy, O; Linard, C | 1 |
Cicek, E; Demirin, H; Gokalp, O; Gokcimen, A; Kocak, A; Koyu, A; Mollaoglu, H; Oktem, F; Ozguner, F | 1 |
Chang, CM; Juang, SJ; Lai, LP; Leu, JG; Liang, YJ; Shyu, KG; Wang, BW | 1 |
Altunbas, A; Cicek, E; Gokalp, O; Ozcelik, N; Ozer, MK; Uz, E; Yilmaz, HR | 1 |
Arimura, K; Higashimoto, I; Matsuyama, W; Mitsuyama, H; Ono, M; Osame, M; Shirahama, Y | 1 |
Cerci, C; Cerci, SS; Cicek, E; Koyu, A; Oral, B; Yildiz, M | 1 |
Aladag, M; Ara, C; Ay, S; Esrefoglu, M; Gul, M; Isik, B; Polat, A; Tekerleklioglu, MS; Yilmaz, S | 1 |
Aslantas, O; Celik, S; Erdogan, S; Gorur, S; Hakverdi, S; Ocak, S | 1 |
Bhattacharyya, S; Borthakur, A; Dudeja, PK; Tobacman, JK | 1 |
Arce-Popoca, E; Carrasco-Legleu, CE; Fattel-Fazenda, S; Hernández-García, S; Márquez-Rosado, L; Sánchez-Pérez, Y; Villa-Treviño, S | 1 |
Aytacoglu, BN; Bayindir, I; Coskun, B; Dikmengil, M; Ersoz, G; Kose, N; Oguz, I; Ozeren, M; Sucu, N; Tamer, L | 1 |
Aslan, H; Atis, O; Ekici, F; Ozyurt, B; Ozyurt, H; Parlaktas, BS | 1 |
Dillman, JF; Minsavage, GD | 1 |
Abdel Gawad, HS; El-Bab, MF; Hammad, LN; Mohamadin, AM | 1 |
Aperis, G; Ausubel, FM; Breger, J; Fuchs, BB; Moy, TI; Mylonakis, E | 1 |
Akpolat, N; Erdogan, H; Ozyurt, B; Ozyurt, H; Sarsilmaz, M | 1 |
Celli, N; Dragani, LK; Murzilli, S; Pagliani, T; Poggi, A | 1 |
Acet, A; Askar, I; Aydogan, H; Aydogan, N; Bay-Karabulut, A; Fariz, A; Gurlek, A; Parlakpinar, H | 1 |
Ansari, MA; Elango, C; Khan, M; Singh, AK; Singh, I | 1 |
Celik, S; Erdogan, S; Gorur, S; Hakverdi, S; Ocak, S | 1 |
Ikota, N; Ishihara, H; Kurematsu, A; Nakanishi, I; Suzuki, K; Tanaka, I; Yakumaru, H | 1 |
Cho, CG; Kwon, SK; Park, SW; Song, JJ | 1 |
Chou, DS; Fong, TH; Hsiao, G; Lee, JJ; Lin, KH; Shen, CH; Sheu, JR | 1 |
Güney, M; Karahan, N; Mungan, T; Nasir, S; Oral, B | 1 |
Cosar, M; Eser, O; Mollaoglu, H; Sahin, O; Sezer, M; Songur, A; Yaman, M | 1 |
Han, M; Kim, HS; Lee, ES; Lee, M; Lee, YM; Park, JM; Park, SH; Suh, PG; Uhm, KO | 1 |
Choi, C; Choi, K; Han, YH | 1 |
Fidan, F; Kara, Z; Sahin, O; Sezer, M; Solak, O; Unlu, M | 1 |
Alrefai, WA; Borthakur, A; Dudeja, PK; Gill, RK; Ramaswamy, K; Saksena, S | 1 |
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Brusman, N; Choi, W; Gonzalez, N; Heppler, B; Hogle, E; Istre, H; Ma, L; Oñate, A; Oñate, S; Paula, S; Snider, L; Tucker, J; Villegas, V | 1 |
Atanasov, AG; Barbat, A; Berindan-Neagoe, I; Braicu, C; Budisan, L; Cojocneanu, R; Gulei, D; Ionescu, C; Irimie, A; Jurj, A; Moldovan, A; Moldovan, C; Pop, L; Raduly, L; Tigu, AB; Zanoaga, O | 1 |
Cheng, CC; Chi, PL; Huang, WC; Liu, CP; Shen, MC; Shu, CW; Tseng, CJ; Wann, SR | 1 |
Hu, XQ; Li, Y; Liu, LH; Yang, JW; Yu, XQ; Zhang, HB; Zhang, YX | 1 |
Bıçakçı, N; Dökmeci, AH; Fidanol Erboğa, Z; Güzel, S; Karaboğa, I | 1 |
Fırat, F; Inan, S; Özgül, M; Türköz Uluer, E | 1 |
Amaral, L; Bernardes, CP; Dos Santos, AC; Dos Santos, NAG; Ferreira, RS; Fontana, ACK; Sisti, FM | 1 |
Chen, C; Huang, L; Jia, Y; Jiang, S; Lu, G; Sun, X; Xie, Y | 1 |
Musa, AE; Shabeeb, D | 1 |
Acquaviva, R; Di Giacomo, C; Intagliata, S; Pittalà, V; Raffaele, M; Salerno, L; Sorrenti, V; Vanella, L | 1 |
Cui, W; Feng, G; Gao, X; Huang, G; Liang, Y; Qin, Y; Tong, Y; Wu, L; Xiao, X; Xu, W; Zhang, Z; Zhong, S; Zhou, X | 1 |
Byun, S; Choi, HK; Choi, S; Jo, S; Lim, TG; Shin, EJ | 1 |
Blake, DJ; Collins, W; Lowen, N | 1 |
Hu, L; Liu, J; Liu, Q; Ning, X; Ren, X; Wang, D | 1 |
Chang, CR; Chuu, CP; Huo, C; Kuo, YY; Lin, CY; Lin, HP; Liu, JS; Wang, WC | 1 |
Karaboğa, İ | 1 |
Kim, BJ; Kim, JN | 1 |
Gül, M; Günay, A; Tanik, A | 1 |
Ilić, I; Janković, R; Marković, D; Sokolović, D; Stošić, B; Stošić, M; Veselinović, I | 1 |
He, W; Huang, Y; Li, M; Li, W; Luo, Y; Mei, Y; Pan, H; Wan, T; Wang, Q; Wang, Z; Xue, J; Zhang, Y | 1 |
Anğın, AD; Başak, K; Çıkman, MS; Gün, I; Kaptanağası, AO; Karakuş, R; Sakin, Ö; Şimşek, EE | 1 |
Hirao, K; Hosokawa, Y; Kitamura, C; Kuramoto, H; Matsuo, T; Nakanishi, T; Takegawa, D; Washio, A; Yumoto, H | 1 |
Arasoglu, T; Ates, SC; Derman, S; Durak, S | 1 |
Bai, X; He, W; Huang, Y; Luo, Y; Mei, Y; Wan, T; Wang, Q; Wang, Z; Xu, Y; Xue, J; Zhang, Y | 1 |
Aksu Kızıldağ, C; Albayrak, M; Arabacı, T; Balseven, HM; Kızıldağ, A; Tasdemir, U | 1 |
Gajek, G; Kontek, R; Lewkowski, J; Marciniak, B | 1 |
Huang, X; Ning, X; Ren, X; Wang, D; Xie, X; Yan, P | 1 |
Akcay, E; Palaz, MN | 1 |
Chen, A; Lin, L; Shao, B; Wang, M; Zhang, C; Zhang, Z | 1 |
Chen, J; Jin, C; Li, Z; Song, P; Song, W; Xuan, Z; Zhang, S; Zheng, S; Zhou, M | 1 |
Dhanjal, JK; Kaul, SC; Kumar, V; Sundar, D; Wadhwa, R | 1 |
Amaral, FLBD; Basting, RT; Bedran-Russo, AK; Bridi, EC; França, FMG; Leme-Kraus, AA; Martinez, EF; Pedrosa, VO; Teixeira, LN; Turssi, CP | 1 |
Fan, D; Liu, X; Luo, M; Luo, Y; Ma, X; Mo, F; Zeng, H; Zhao, Y | 1 |
Khare, S; Khare, T; Palakurthi, S; Palakurthi, SS; Shah, BM | 1 |
Ding, L; Li, H; Li, W; Niu, Y; Ren, Q; Wang, K; Wang, Y; Zhang, L; Zheng, S | 1 |
Cantürk Tan, F; Ceylan, T; Kaymak, E; Yakan, B | 1 |
Abdik, H; Avşar Abdik, E; Sahin, F; Turan, D | 1 |
Cholewa, K; Dzik, R; Jasik, K; Kabała-Dzik, A; Kleczka, A; Kubina, R; Stojko, J | 1 |
Cao, D; Huang, CH; Huang, R; Lin, L; Mao, L; Qin, L; Shao, B; Shao, J; Sheng, ZG; Zhang, CZ; Zhang, ZQ; Zhu, BZ | 1 |
Bai, HW; Hong, CJ; Wang, P; Yamabe, N; Zhu, BT | 1 |
Gulhan, MF; Ozdemir, B; Sahna, E; Selamoglu, Z | 1 |
Ali, MA; Menze, ET; Tadros, MG; Tolba, MF | 1 |
Leible, M; Lin, J; Wang, A; Weiss, J; Zhong, Q | 1 |
da Silva, CCS; Fontes-Júnior, EA; Luz, DA; Maia, CSF; Martins, MAT; Martins, MD; Menezes da Silveira, CCS; Prediger, RDS | 1 |
Hogan, L; Kim, MJ; Lassalle-Claux, G; Luiker, K; Murugesan, A; Reiman, T; Selka, A; Touaibia, M; Vaillancourt, E | 1 |
Artaş, G; Dündar, S; Gül, M; Özcan, EC; Polat, ME; Tanık, A; Yiğin, A | 1 |
Auh, JH; Byun, S; Choi, S; Hong, S; Kim, DH; Lim, TG; Oh, J; Shin, EJ; Woo, SO | 1 |
Amorati, R; Baschieri, A; Guo, Y; Valgimigli, L | 1 |
Cao, Y; Du, Q; Jiang, Y; Jiao, X; Li, Y; Liu, X; Tang, M; Tian, C; Wang, Y; Wang, Z; Xie, P; Yang, J | 1 |
Novinec, M; Ulčakar, L | 1 |
Kapare, HS; Lohidasan, S; Mahadik, K; Sinnathambi, A | 1 |
Akil, M | 1 |
Cui, H; Liu, X; Lv, L; Ma, Z; Yang, L | 1 |
Balaha, M; Cataldi, A; De Filippis, B; di Giacomo, V | 1 |
Kaul, SC; Kumar, V; Malik, V; Sundar, D; Wadhwa, R | 1 |
Qin, J; Wa, W; Wang, Y; Yang, M; Zheng, J | 1 |
Fujita, R; Hanaya, K; Hashimoto, R; Higashibayashi, S; Iai, H; Inoue, H; Sugai, T | 1 |
Bilgici, B; Demir, E; Lütfioğlu, M; Otan Özden, F | 1 |
Anna, B; Emilia, M; Kamila, Ż; Olgierd, B | 1 |
Huang, YK; Lee, CY; Shen, MY; Tsai, PH; Tseng, KF; Wang, JS | 1 |
Belduz, AO; Guler, HI; Kolayli, S; Tatar, G; Yildiz, O | 1 |
Ilić, B; Krtinić, D; Milojković, M; Pavlović, M; Rančić, A; Rančić, M; Ristić, L; Sokolović, D; Živković, N | 1 |
Ding, XJ; Hu, XQ; Liu, LH; Yang, JW; Yu, XQ; Zhang, HB | 1 |
Kulkarni, NP; Narula, AS; Sharma, SS; Vaidya, B | 1 |
Cui, Z; Dong, H; Gong, Q; Hu, G; Huang, H; Li, D; Li, Z; Liu, T; Pei, Z; Shao, J; Tan, Y; Wang, J; Wang, K; Wang, Q; Zhang, Q; Zhang, S; Zhao, S | 1 |
Choi, SH; Jeong, YI; Kang, S; Lee, DY; Lee, HL; Lee, HY; Lee, JH; Lee, MK; Lee, SH | 1 |
de Castro Raucci, LMS; Demasi, APD; Joly, JC; Martinez, EF; Santos, PHN; Silva, HL; Teixeira, LN | 1 |
Bhargava, P; Ishida, Y; Kaul, A; Kaul, SC; Mahanta, D; Terao, K; Wadhwa, R | 1 |
Bagatini, MD; de Oliveira Maciel, SFV; de Resende E Silva, DT; do Carmo, TIT; Dos Anjos, F; Soares, VEM; Wruck, J | 1 |
Akmayan, I; Arasoglu, T; Derman, S; Egri, O; Kaya, S; Yilmaz, DE | 1 |
Han, Y; Li, B; Li, Z; Luo, Z; Wan, Q | 1 |
Gur, C; Ileriturk, M; Kandemir, FM; Kaynar, O; Semis, HS | 1 |
Abdallah, EAA; El-Refaei, MF | 1 |
Fakhoury, VS; Inacio, KK; Oliveira, GSN; Oliveira, RC; Pagnan, AL; Pessoa, AS; Sanches, MLR; Tokuhara, CK; Ximenes, VF | 1 |
Cao, Y; Cui, G; Han, H; Kong, D; Zhang, Y; Zhu, H | 1 |
Arrighetti, N; Carenini, N; Colombo, D; Corna, E; Costantino, M; D'Arcy, P; De Cesare, M; Gatti, L; Linder, S; Perego, P; Sjöstrand, L; Zuccolo, M | 1 |
Kırzıoğlu, FY; Özmen, Ö; Yiğit, U | 1 |
Chuu, CP; Fu, YK; Hour, TC; Huang, SH; Kuo, YY; Lin, CY; Tseng, JC; Wang, BJ | 1 |
Manzanilla, B; Robles, J | 1 |
Almas, F; Dogan, B; Durdagi, S; Guzel, M; Guzel, MA; Karakas, N; Koc, EB; Mirat, A; Savlug Ipek, O; Sucu, BO; Uludag, D | 1 |
Barone, E; Butterfield, DA; Caforio, M; Di Domenico, F; Folgiero, V; Locatelli, F; Pagnotta, S; Perluigi, M; Petrini, S; Pittalà, V; Salerno, L; Tramutola, A | 1 |
Chen, Y; Hao, S; Liu, J; Nai, X; Xuan, H; Zhang, Q | 1 |
Chien, CY; Chiu, KC; Hsia, SM; Kuo, YH; Li, PJ; Shieh, TM; Shih, YH; Wang, TH | 1 |
Cai, M; Chen, S; Gao, X; Hu, H; Huang, L; Li, X; Liang, D; Liu, Y; Wu, Q; Xiao, C; Xie, Y; Yong, T | 1 |
Adhikari, N; Shim, WS | 1 |
Cicek, M; Demir, M; Deresoy, FA; Eser, N; Yoldas, A | 1 |
Chen, P; Chen, X; Dai, J; Du, Y; Huang, Y; Li, R; Liu, L; Wang, L; Wang, Q; Wang, Z; Wei, X; Yang, X; Zhou, Z | 1 |
Hao, L; Li, X; Liu, K; Liu, Y; Lu, J; Shao, Y; Wang, X; Yi, J; Zhang, X | 1 |
Algburi, FS; Caglayan, C; Taysi, ME; Taysi, S | 1 |
Cho, SD; Shin, JA; Yu, HJ | 1 |
Basu, B; Ishida, Y; Kaul, A; Kaul, SC; Kumar, V; Meidinna, HN; Sari, AN; Sundar, D; Terao, K; Vrati, S; Wadhwa, R | 1 |
Barnstable, CJ; Li, X; Ren, C; Tombran-Tink, J; Yu, Z; Zhang, M; Zhang, X; Zhou, P | 1 |
Giri, PP; Khan, F; Pandey, P; Upadhyay, TK | 1 |
He, C; Huang, X; Ling, M; Xu, Y; Zhou, Z | 1 |
Chen, Y; Kong, J; Li, M; Li, Y; Liu, J; Liu, M; Nai, X; Yan, H; Zhang, Q; Zhao, Z | 1 |
Hagvall, L; Hurben, AK; Karlsson, I; Ndreu, L; Nyman, GSA; Tretyakova, NY | 1 |
Chen, JK; Chuu, CP; Hour, TC; Hsiao, PJ; Kao, CL; Kuo, LK; Kuo, YY; Shih, LJ; Tseng, JC; Wang, BJ; Wang, YP; Yeh, CC | 1 |
Basarslan, F; Basarslan, SK | 1 |
Chen, L; Ding, H; Fang, L; Fang, Q; Fu, Y; Qi, Y; Xin, W | 1 |
Dzik, R; Kabała-Dzik, A; Kleczka, A | 1 |
30 review(s) available for caffeic acid phenethyl ester and phenylethyl alcohol
Article | Year |
---|---|
[NF-kappa B as a therapeutic drug target].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arteriosclerosis; Caffeic Acids; DNA-Binding Proteins; Drug Design; Flavonoids; Gene Transfer Techniques; Humans; I-kappa B Proteins; Immunosuppressive Agents; Inflammation; Mutation; Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Steroids | 2001 |
Evaluation of natural and synthetic compounds from East Asiatic folk medicinal plants on the mediation of cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Asia, Eastern; Benzofurans; Caffeic Acids; Coumarins; Flavonoids; Hibiscus; Humans; Medicine, Traditional; Mice; Phenylethyl Alcohol; Piper; Plant Preparations | 2006 |
Cytotoxic constituents of propolis inducing anticancer effects: a review.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Diterpenes; Flavonoids; Humans; Neoplasms; Phenylethyl Alcohol; Propolis | 2011 |
The potential usage of caffeic acid phenethyl ester (CAPE) against chemotherapy-induced and radiotherapy-induced toxicity.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Neoplasms, Experimental; Phenylethyl Alcohol | 2012 |
The immunomodulatory and anticancer properties of propolis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Caffeic Acids; Cell Line, Tumor; Humans; Immunologic Factors; Neoplasms; Neoplastic Stem Cells; Oncogene Proteins; Phenylethyl Alcohol; Phenylpropionates; Propolis; Signal Transduction; T-Lymphocyte Subsets; Tumor Microenvironment | 2013 |
Development of polyphenols as HIV-1 integrase inhibitors: a summary and perspective.
Topics: Animals; Caffeic Acids; Drug Design; HIV Integrase Inhibitors; Humans; Phenylethyl Alcohol; Polyphenols; Structure-Activity Relationship | 2012 |
The anticancer mechanism of caffeic acid phenethyl ester (CAPE): review of melanomas, lung and prostate cancers.
Topics: Antineoplastic Agents; Caffeic Acids; Humans; Lung Neoplasms; Male; Melanoma; Phenylethyl Alcohol; Prostatic Neoplasms | 2012 |
In vivo and in vitro antıneoplastic actions of caffeic acid phenethyl ester (CAPE): therapeutic perspectives.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Central Nervous System Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Leukemia; Phenylethyl Alcohol; Propolis | 2013 |
Caffeic acid phenethyl ester, a promising component of propolis with a plethora of biological activities: a review on its anti-inflammatory, neuroprotective, hepatoprotective, and cardioprotective effects.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bees; Biological Availability; Caffeic Acids; Cardiotonic Agents; Liver; Neuroprotective Agents; Phenylethyl Alcohol | 2013 |
Caffeic acid phenethyl ester and therapeutic potentials.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Humans; Phenylethyl Alcohol; Propolis | 2014 |
Caffeic acid phenethyl ester as a protective agent against nephrotoxicity and/or oxidative kidney damage: a detailed systematic review.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Antioxidants; Caffeic Acids; Humans; Oxidative Stress; Phenylethyl Alcohol | 2014 |
Caffeic acid phenethyl ester: its protective role against certain major eye diseases.
Topics: Animals; Bees; Caffeic Acids; Disease Models, Animal; Eye Diseases; Humans; NF-kappa B; Phenylethyl Alcohol; Propolis | 2014 |
Bioactivity and chemical synthesis of caffeic acid phenethyl ester and its derivatives.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Caffeic Acids; Cell Line, Tumor; Humans; Phenylethyl Alcohol; Propolis | 2014 |
Caffeic Acid Phenethyl Ester: A Review of Its Antioxidant Activity, Protective Effects against Ischemia-reperfusion Injury and Drug Adverse Reactions.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Caffeic Acids; Drug-Related Side Effects and Adverse Reactions; Humans; Phenylethyl Alcohol; Propolis; Reperfusion Injury | 2016 |
Future opportunities in preventing ototoxicity: Caffeic acid phenethyl ester may be a candidate (Review).
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Humans; Myringosclerosis; Otitis Media; Oxidative Stress; Phenylethyl Alcohol; Propolis | 2015 |
Caffeic Acid phenethyl ester is a potential therapeutic agent for oral cancer.
Topics: Animals; Caffeic Acids; Humans; Mouth Neoplasms; Phenylethyl Alcohol | 2015 |
Melatonin and caffeic acid phenethyl ester in the regulation of mitochondrial function and apoptosis: The basis for future medical approaches.
Topics: Animals; Apoptosis; Caffeic Acids; Forecasting; Humans; Melatonin; Mitochondria; Phenylethyl Alcohol | 2016 |
Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes.
Topics: Animals; Antioxidants; Caffeic Acids; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Humans; Oxidative Stress; Phenylethyl Alcohol; Polyphenols | 2018 |
Radio-Modulatory Potential of Caffeic Acid Phenethyl Ester: A Therapeutic Perspective.
Topics: Antineoplastic Agents; Caffeic Acids; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Phenylethyl Alcohol; Structure-Activity Relationship | 2018 |
Radiation-Induced Heart Diseases: Protective Effects of Natural Products.
Topics: Biological Products; Caffeic Acids; Curcumin; Drug Combinations; Drugs, Chinese Herbal; Guaiacol; Heart Diseases; Hesperidin; Humans; Melatonin; Phenylethyl Alcohol; Protective Factors; Radiation Injuries; Selenium; Vitis | 2019 |
Natural Product-Based Nanomedicine in Treatment of Inflammatory Bowel Disease.
Topics: Animals; Benzoquinones; Biological Products; Biomimetics; Caffeic Acids; Curcumin; Cytokines; Exosomes; Humans; Inflammation; Inflammatory Bowel Diseases; Insecta; Macromolecular Substances; Nanomedicine; Oxidative Stress; Phenylethyl Alcohol; Phytochemicals; Plant Extracts; Polysaccharides; Quercetin; Resveratrol; Stilbenes; Transcription Factors; Translational Research, Biomedical; Vasoactive Intestinal Peptide; Zingiber officinale | 2020 |
Propolis: A useful agent on psychiatric and neurological disorders? A focus on CAPE and pinocembrin components.
Topics: Animals; Bees; Caffeic Acids; Flavanones; Humans; Nervous System Diseases; Phenylethyl Alcohol; Propolis | 2021 |
Recent progresses in the pharmacological activities of caffeic acid phenethyl ester.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Caffeic Acids; Drug Development; Humans; Neuroprotective Agents; NF-kappa B; Phenylethyl Alcohol; Propolis | 2021 |
CAPE and Neuroprotection: A Review.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents; Antifungal Agents; Antioxidants; Antiviral Agents; Apoptosis; Brain; Caffeic Acids; Humans; Inflammation; Ischemia; Neurodegenerative Diseases; Parkinson Disease; Phenylethyl Alcohol; Propolis; Psychotic Disorders; Seizures | 2021 |
The Pluripotent Activities of Caffeic Acid Phenethyl Ester.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Caffeic Acids; Humans; Phenylethyl Alcohol | 2021 |
Experimental Evidence for Therapeutic Potentials of Propolis.
Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents; Antioxidants; Brazil; Caffeic Acids; Humans; New Zealand; Phenylethyl Alcohol; Phenylpropionates; Propolis | 2021 |
Role of inflammation and oxidative stress in tissue damage associated with cystic fibrosis: CAPE as a future therapeutic strategy.
Topics: Anti-Inflammatory Agents; Caffeic Acids; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Inflammation; Mutation; Oxidative Stress; Phenylethyl Alcohol | 2022 |
CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down Syndrome.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Caffeic Acids; Down Syndrome; Humans; Kelch-Like ECH-Associated Protein 1; Mice; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol | 2022 |
Caffeic acid phenethyl ester: A review on its pharmacological importance, and its association with free radicals, COVID-19, and radiotherapy.
Topics: Anti-Inflammatory Agents; Caffeic Acids; COVID-19; Free Radicals; Humans; Molecular Docking Simulation; Phenylethyl Alcohol; SARS-CoV-2 | 2023 |
Therapeutic efficacy of caffeic acid phenethyl ester in cancer therapy: An updated review.
Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Humans; Neoplasms; Phenylethyl Alcohol; Propolis | 2023 |
1 trial(s) available for caffeic acid phenethyl ester and phenylethyl alcohol
Article | Year |
---|---|
Nanoleakage inhibition within hybrid layer using new protective chemicals and their effect on adhesion.
Topics: Acrylates; Acrylic Resins; Bisphenol A-Glycidyl Methacrylate; Boron Compounds; Caffeic Acids; Cementation; Dental Bonding; Dental Cements; Dental Leakage; Dental Porcelain; Dentin; Dentin-Bonding Agents; Enzyme Inhibitors; Fluorides; Humans; Materials Testing; Methacrylates; Methylmethacrylate; Methylmethacrylates; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Phenylethyl Alcohol; Resin Cements; Silver Staining; Stress, Mechanical; Tensile Strength; Titanium | 2011 |
699 other study(ies) available for caffeic acid phenethyl ester and phenylethyl alcohol
Article | Year |
---|---|
Caffeic acid phenethyl ester inhibits alpha-melanocyte stimulating hormone-induced melanin synthesis through suppressing transactivation activity of microphthalmia-associated transcription factor.
Topics: alpha-MSH; Animals; Blotting, Western; Caffeic Acids; Cyclic AMP Response Element-Binding Protein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Interferon Type I; Intramolecular Oxidoreductases; Levodopa; Melanins; Mice; Microphthalmia-Associated Transcription Factor; Molecular Structure; Monophenol Monooxygenase; Oxidoreductases; Phenylethyl Alcohol; Pregnancy Proteins; Transcriptional Activation | 2013 |
Growth inhibition and modulation of antigenic phenotype in human melanoma and glioblastoma multiforme cells by caffeic acid phenethyl ester (CAPE)
Topics: Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Caffeic Acids; Cell Differentiation; Cell Division; Cytotoxins; Diterpenes; Glioblastoma; Humans; Melanoma; Mycophenolic Acid; Phenotype; Phenylethyl Alcohol; Terpenes; Tretinoin; Tumor Cells, Cultured | 1992 |
Suppression of adenovirus type 5 E1A-mediated transformation and expression of the transformed phenotype by caffeic acid phenethyl ester (CAPE).
Topics: Actins; Adenoviridae; Adenovirus Early Proteins; Animals; Caffeic Acids; Cell Line; Cell Line, Transformed; Cell Transformation, Viral; Cold Temperature; DNA; Fibroblasts; Gene Expression Regulation, Viral; Methyl Methanesulfonate; Mice; Mutation; Oncogene Proteins, Viral; Phenotype; Phenylethyl Alcohol; Rats; Rats, Inbred F344; RNA, Messenger; Transfection | 1991 |
Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis.
Topics: Animals; Caffeic Acids; Cell Division; Cell Survival; Cells, Cultured; Cinnamates; Cytotoxins; DNA; Ethanol; In Vitro Techniques; Phenylethyl Alcohol; Propolis; Rats; Resins, Plant | 1988 |
Hydroxylated aromatic inhibitors of HIV-1 integrase.
Topics: Animals; Antiviral Agents; Apoptosis; Base Sequence; Binding Sites; Caffeic Acids; Cell Line, Transformed; DNA; DNA Nucleotidyltransferases; Enzyme Inhibitors; HIV; Humans; Hydroxylation; Integrases; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Phenylethyl Alcohol; Rats; Structure-Activity Relationship; Tumor Cells, Cultured; Zinc Fingers | 1995 |
Growth suppression and toxicity induced by caffeic acid phenethyl ester (CAPE) in type 5 adenovirus-transformed rat embryo cells correlate directly with transformation progression.
Topics: Adenovirus E1A Proteins; Adenovirus E1B Proteins; Adenoviruses, Human; Animals; Caffeic Acids; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cytotoxins; Embryo, Mammalian; Gene Expression; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Transcription, Genetic | 1994 |
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds.
Topics: Base Sequence; Caffeic Acids; Cations, Divalent; DNA; DNA Nucleotidyltransferases; Dose-Response Relationship, Drug; Flavonoids; HIV-1; Integrases; Kinetics; Molecular Sequence Data; Oligonucleotides; Phenylethyl Alcohol; Structure-Activity Relationship | 1994 |
[Lipophilic derivatives of caffeic acid as lipoxygenase inhibitors with antioxidant properties].
Topics: Antioxidants; Caffeic Acids; Cell-Free System; Glycine max; Hordeum; Humans; Lipids; Lipoxygenase Inhibitors; Phenylethyl Alcohol; Reactive Oxygen Species; Urea | 1995 |
Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells.
Topics: Acetylcysteine; Animals; Apoptosis; Caffeic Acids; Catalase; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA Damage; Glutathione; Hydrogen Peroxide; Oxidation-Reduction; Phenylethyl Alcohol; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344 | 1995 |
Inhibition of tumor promoter-mediated processes in mouse skin and bovine lens by caffeic acid phenethyl ester.
Topics: Animals; Caffeic Acids; Cattle; Cytotoxins; DNA; Edema; Female; Humans; Hydrogen Peroxide; In Vitro Techniques; Lens, Crystalline; Mice; Neutrophils; Ornithine Decarboxylase; Phenylethyl Alcohol; Skin; Tetradecanoylphorbol Acetate | 1993 |
Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties.
Topics: Antioxidants; Caffeic Acids; Hordeum; Humans; Kinetics; Linoleic Acid; Linoleic Acids; Lipoxygenase Inhibitors; Luminescent Measurements; Neutrophils; Oxidation-Reduction; Phenylethyl Alcohol; Reactive Oxygen Species; Xanthine; Xanthine Oxidase; Xanthines | 1993 |
Inhibition of oxidative stress in HeLa cells by chemopreventive agents.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Anticarcinogenic Agents; Antineoplastic Agents; Caffeic Acids; Catechin; Deoxyguanosine; Diterpenes; DNA, Neoplasm; HeLa Cells; Humans; Hydrogen Peroxide; Hydrolyzable Tannins; Oxidation-Reduction; Phenylethyl Alcohol; Tamoxifen; Tannins; Tetradecanoylphorbol Acetate; Thymidine | 1993 |
Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Caffeic Acids; Carcinogens; DNA; DNA Damage; Female; HeLa Cells; Humans; Mice; Oxidative Stress; Papilloma; Phenylethyl Alcohol; Protein Biosynthesis; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.
Topics: Base Sequence; Caffeic Acids; Cell Line; Ceramides; DNA-Binding Proteins; Histiocytes; Humans; I-kappa B Proteins; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Phenylethyl Alcohol; Phosphorylation; Protein Binding; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Caffeic acid phenethyl ester inhibits proliferation of human keratinocytes and interferes with the EGF regulation of ornithine decarboxylase.
Topics: Binding Sites; Blotting, Northern; Blotting, Western; Caffeic Acids; Cell Division; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Humans; Keratinocytes; Male; Ornithine Decarboxylase; Phenylethyl Alcohol; Protein Kinase C; Signal Transduction; Time Factors | 1995 |
Inhibition of ICE-family cysteine proteases rescues murine lymphocytes from lipoxygenase inhibitor-induced apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caffeic Acids; Caspase 1; Cell Division; Cells, Cultured; Concanavalin A; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Lipoxygenase Inhibitors; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Phenylethyl Alcohol; Propolis; Quercetin; T-Lymphocytes; Urea | 1996 |
Inhibitory effect of caffeic acid phenethyl ester on human leukemia HL-60 cells.
Topics: Anticarcinogenic Agents; Caffeic Acids; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Phenylethyl Alcohol | 1996 |
Caffeic acid phenethyl ester stimulates human antioxidant response element-mediated expression of the NAD(P)H:quinone oxidoreductase (NQO1) gene.
Topics: Antioxidants; Caffeic Acids; DNA; Humans; Phenylethyl Alcohol; Quinone Reductases; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1997 |
The effect of propolis and its components on eicosanoid production during the inflammatory response.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Caffeic Acids; Cyclooxygenase Inhibitors; Diet; Eicosanoids; Flavanones; Flavonoids; Indomethacin; Inflammation; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Masoprocol; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phenylethyl Alcohol; Propolis; Quercetin; Urea; Zymosan | 1996 |
HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching.
Topics: Caffeic Acids; Chromones; Databases, Factual; Drug Design; Electrophoresis, Polyacrylamide Gel; Flavones; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Molecular Conformation; Molecular Structure; Oligodeoxyribonucleotides; Phenylethyl Alcohol | 1997 |
Arylamide inhibitors of HIV-1 integrase.
Topics: Caffeic Acids; Chromatography, High Pressure Liquid; Curcumin; Cytotoxins; Dose-Response Relationship, Drug; Enzyme Inhibitors; HIV Integrase; HIV Integrase Inhibitors; NF-kappa B; Phenylethyl Alcohol; Quinones; Structure-Activity Relationship | 1997 |
Ultraviolet B suppresses vitamin D receptor gene expression in keratinocytes.
Topics: Caffeic Acids; Cells, Cultured; Cholecalciferol; Dose-Response Relationship, Radiation; Down-Regulation; Feedback; Gene Expression Regulation; Genes, myc; Humans; Keratinocytes; Phenylethyl Alcohol; Receptors, Calcitriol; RNA, Messenger; Signal Transduction; Sodium Salicylate; Tosylphenylalanyl Chloromethyl Ketone; Ultraviolet Rays | 1998 |
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.
Topics: Air; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arachidonic Acids; Caffeic Acids; Calcimycin; Carcinoma, Squamous Cell; Carrageenan; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Genetic Vectors; Humans; Indomethacin; Inflammation; Ionophores; Isoenzymes; Male; Membrane Lipids; Membrane Proteins; Mouth Mucosa; Nucleopolyhedroviruses; Phenylethyl Alcohol; Phospholipids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1999 |
Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats.
Topics: Animals; Caffeic Acids; Cytotoxins; Evaluation Studies as Topic; Female; Intestinal Mucosa; Intestines; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury | 1999 |
Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex.
Topics: Antineoplastic Agents; Caffeic Acids; Colonic Neoplasms; Curcumin; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; I-kappa B Kinase; I-kappa B Proteins; Isoenzymes; Membrane Proteins; NF-kappa B; NF-kappaB-Inducing Kinase; Phenylethyl Alcohol; Polyenes; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
The effects of caffeic acid phenethyl ester (CAPE) on spinal cord ischemia/reperfusion injury in rabbits.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Malondialdehyde; Methylprednisolone; Movement; Neuroprotective Agents; NF-kappa B; Phenylethyl Alcohol; Rabbits; Reperfusion Injury; Spinal Cord; Spinal Cord Ischemia; Superoxide Dismutase | 1999 |
Effect of quercetin, caffeic acid and caffeic acid phenylethyl ester, solubilized in non-ionic surfactants, on histamine release in vivo and in vitro.
Topics: Animals; Antioxidants; Caffeic Acids; Cytotoxins; Histamine; Histamine Release; In Vitro Techniques; Mast Cells; Phenylethyl Alcohol; Quercetin; Rats; Rats, Wistar; Surface-Active Agents | 2000 |
Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation.
Topics: Acute Disease; Animals; Apoptosis; Caffeic Acids; Carrageenan; Cell Survival; Dexamethasone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Humans; I-kappa B Proteins; Inflammation; Lethal Dose 50; Leukocyte Count; Leukocytes; Monocytes; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Transcription Factor RelA; Tumor Cells, Cultured | 2000 |
Colon cancer chemopreventive drugs modulate integrin-mediated signaling pathways.
Topics: Actins; Antineoplastic Agents; Caffeic Acids; Cell Movement; Colonic Neoplasms; Crk-Associated Substrate Protein; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrins; Phenylethyl Alcohol; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Signal Transduction; Sulindac; Tumor Cells, Cultured | 2000 |
Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells.
Topics: Antineoplastic Agents; Caffeic Acids; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mouth Neoplasms; Phenylethyl Alcohol; Tumor Cells, Cultured | 2000 |
Restoration of gap junctional intercellular communication by caffeic acid phenethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line.
Topics: Animals; Anticarcinogenic Agents; Caffeic Acids; Cell Adhesion; Cell Communication; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Connexin 43; Epithelial Cells; Gap Junctions; Gene Expression; Genes, ras; Liver; Oncogene Protein p21(ras); Phenylethyl Alcohol; Phosphorylation; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction | 2000 |
Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-kappaB.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Arteries; Caffeic Acids; Cell Survival; Cells, Cultured; Coronary Vessels; DNA-Binding Proteins; Endothelium, Vascular; Humans; I-kappa B Proteins; L-Lactate Dehydrogenase; Lipoproteins, LDL; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Up-Regulation; Vitamin E | 2000 |
Caffeic acid phenethyl ester (CAPE): synthesis and X-ray crystallographic analysis.
Topics: Caffeic Acids; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Molecular Structure; Phenylethyl Alcohol; Spectrophotometry, Infrared | 2001 |
Testicular nitric oxide levels after unilateral testicular torsion/detorsion in rats pretreated with caffeic acid phenethyl ester.
Topics: Animals; Caffeic Acids; Male; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Inbred Strains; Reperfusion Injury; Spermatic Cord Torsion; Testis | 2000 |
The antioxidant caffeic acid phenethyl ester induces apoptosis associated with selective scavenging of hydrogen peroxide in human leukemic HL-60 cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Caffeic Acids; Catalase; Cell Cycle; Cytotoxins; DNA Damage; DNA, Neoplasm; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Oxidation-Reduction; Phenylethyl Alcohol; Reactive Oxygen Species; Superoxides | 2001 |
Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester.
Topics: Animals; Apoptosis; Blotting, Western; Boron Compounds; Caffeic Acids; Carcinogens; Caspase 3; Caspases; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Methacrylates; Methylmethacrylates; Mice; Phenylethyl Alcohol; Phosphorylation; Precipitin Tests; Serine; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53 | 2001 |
The effect of caffeic acid phenethyl ester on ischemia-reperfusion injury in comparison with alpha-tocopherol in rat kidneys.
Topics: alpha-Tocopherol; Animals; Antioxidants; Caffeic Acids; Female; Kidney; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Xanthine Oxidase | 2001 |
Effects of caffeic acid phenethyl ester and epidermal growth factor on the development of caustic esophageal stricture in rats.
Topics: Animals; Burns, Chemical; Caffeic Acids; Epidermal Growth Factor; Esophageal Stenosis; NF-kappa B; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Wound Healing | 2001 |
Acute regulation of glucose transport in a human megakaryocytic cell line: difference between growth factors and H(2)O(2).
Topics: Caffeic Acids; Catalase; Deoxyglucose; Enzyme Inhibitors; Genistein; Glucose; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Hydrogen Peroxide; Interleukin-3; Kinetics; Leukemia, Megakaryoblastic, Acute; Phenylethyl Alcohol; Protein-Tyrosine Kinases; Stem Cell Factor; Thrombopoietin; Tumor Cells, Cultured | 2001 |
Effect of propolis extract on malignant cell transformation by moloney murine sarcoma virus.
Topics: 3T3 Cells; Animals; Caffeic Acids; Cell Transformation, Neoplastic; Cell Transformation, Viral; Mice; Moloney murine sarcoma virus; Phenylethyl Alcohol; Propolis | 2001 |
Effect of caffeic acid phenethyl ester, an antioxidant from propolis, on inducing apoptosis in human leukemic HL-60 cells.
Topics: Antioxidants; Apoptosis; Caffeic Acids; Cell Division; Flow Cytometry; HL-60 Cells; Humans; Phenylethyl Alcohol; Propolis | 2001 |
Caffeic acid phenethyl ester, an inhibitor of nuclear factor-kappaB, attenuates bacterial peptidoglycan polysaccharide-induced colitis in rats.
Topics: Animals; Apoptosis; Arthritis; Caffeic Acids; Cells, Cultured; Colitis; Colon; Cytokines; Disease Models, Animal; Female; Humans; NF-kappa B; Peptidoglycan; Phenylethyl Alcohol; Rats; Rats, Inbred Lew | 2001 |
Caffeic acid phenethyl ester inhibits nitric oxide synthase gene expression and enzyme activity.
Topics: Animals; Caffeic Acids; Cell Line; Cytotoxins; DNA Primers; Gene Expression Regulation; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophages; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 2002 |
Caffeic acid phenethyl ester changes the indices of oxidative stress in serum of rats with renal ischaemia-reperfusion injury.
Topics: Adenosine Deaminase; alpha-Tocopherol; Animals; Antioxidants; Caffeic Acids; Female; Kidney; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rats; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 2001 |
Effect of caffeic acid phenethyl ester on corneal neovascularization in rats.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caffeic Acids; Cornea; Corneal Neovascularization; Dexamethasone; Glucocorticoids; Indomethacin; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2001 |
Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers.
Topics: Acetylcysteine; Animals; Astrocytes; Caffeic Acids; Cell Survival; Cells, Cultured; Curcumin; Drug Interactions; Enzyme Activation; Enzyme Induction; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Phenylethyl Alcohol; Rats; Up-Regulation | 2002 |
Nuclear factor-kappa B-independent regulation of lipopolysaccharide-mediated interleukin-6 biosynthesis.
Topics: Animals; Caffeic Acids; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Interleukin-6; Leupeptins; Lipopolysaccharides; Multienzyme Complexes; NF-kappa B; Peptides; Phenylethyl Alcohol; Proteasome Endopeptidase Complex; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Sulfasalazine | 2002 |
Beneficial effects of caffeic acid phenethyl ester in a rat model of vascular injury.
Topics: Actins; Angioplasty, Balloon, Coronary; Animals; Caffeic Acids; Carotid Artery Injuries; Cyclooxygenase 2; Depression, Chemical; Electrophoretic Mobility Shift Assay; Isoenzymes; Macrophages; Male; NF-kappa B; Phenylethyl Alcohol; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tunica Intima | 2002 |
Constituents of Chinese propolis and their antiproliferative activities.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Caffeic Acids; China; Chromatography, Thin Layer; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Free Radical Scavengers; Mice; Molecular Structure; Phenylethyl Alcohol; Picrates; Propolis; Spectrophotometry, Infrared; Tumor Cells, Cultured | 2002 |
Selective antiproliferative activity of caffeic acid phenethyl ester analogues on highly liver-metastatic murine colon 26-L5 carcinoma cell line.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Division; Colonic Neoplasms; DNA Fragmentation; Drug Screening Assays, Antitumor; Hepatocytes; Humans; Liver Neoplasms; Mice; Phenylethyl Alcohol; Structure-Activity Relationship; Tumor Cells, Cultured | 2002 |
Use of caffeic acid phenethyl ester to prevent sodium-selenite-induced cataract in rat eyes.
Topics: Animals; Antioxidants; Caffeic Acids; Cataract; Glutathione; Lens, Crystalline; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Inbred Strains; Sodium Selenite | 2002 |
Regulation of Fas (CD95)-induced apoptosis by nuclear factor-kappaB and tumor necrosis factor-alpha in macrophages.
Topics: Animals; Antibodies; Apoptosis; Caffeic Acids; Cell Line; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Fas Ligand Protein; fas Receptor; Flow Cytometry; Genes, Reporter; Macrophages; Membrane Glycoproteins; Mice; NF-kappa B; Phenylethyl Alcohol; Promoter Regions, Genetic; Recombinant Fusion Proteins; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha | 2002 |
Inhibition of angiogenesis by propolis.
Topics: Angiogenesis Inhibitors; Animals; Caffeic Acids; Cattle; Cell Division; Chick Embryo; Chorion; Endothelium, Vascular; Ethanol; Keratolytic Agents; Membranes; Phenylethyl Alcohol; Propolis; Pulmonary Artery; Solvents; Tetrazolium Salts; Thiazoles; Tretinoin | 2002 |
The protective role of caffeic acid phenethyl ester (CAPE) on testicular tissue after testicular torsion and detorsion.
Topics: Animals; Caffeic Acids; Catalase; Disease Models, Animal; Glutathione Peroxidase; Male; Peroxidase; Phenylethyl Alcohol; Protective Agents; Rats; Reperfusion Injury; Spermatic Cord Torsion; Superoxide Dismutase; Testis; Thiobarbituric Acid Reactive Substances | 2002 |
The inhibitory effect of propolis and caffeic acid phenethyl ester on cyclooxygenase activity in J774 macrophages.
Topics: Animals; Caffeic Acids; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Flavonoids; Isoenzymes; Macrophages; Phenylethyl Alcohol; Propolis; Prostaglandin-Endoperoxide Synthases | 2002 |
Effect of caffeic acid phenethyl ester on cartilage in experimental osteoarthritis.
Topics: Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Caffeic Acids; Cartilage, Articular; Disease Models, Animal; Disease Progression; Extracellular Matrix; Hindlimb; Injections, Intra-Articular; NF-kappa B; Osteoarthritis, Knee; Phenylethyl Alcohol; Proteoglycans; Rabbits | 2002 |
Antioxidant activity of propolis: role of caffeic acid phenethyl ester and galangin.
Topics: Antioxidants; Biphenyl Compounds; Caffeic Acids; Dose-Response Relationship, Drug; Flavonoids; Free Radical Scavengers; Humans; Lipid Peroxidation; Phenylethyl Alcohol; Phytotherapy; Picrates; Plant Extracts; Propolis; Xanthine Oxidase | 2002 |
The role of the phenethyl ester of caffeic acid (CAPE) in the inhibition of rat lung cyclooxygenase activity by propolis.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Flavonoids; Inhibitory Concentration 50; Lipopolysaccharides; Lung; Male; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Propolis; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 2002 |
Effect of a propolis extract and caffeic acid phenethyl ester on formation of aberrant crypt foci and tumors in the rat colon.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Caffeic Acids; Colon; Colonic Neoplasms; Male; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Propolis; Random Allocation; Rats; Rats, Wistar | 2002 |
In vitro permeation through porcine buccal mucosa of caffeic acid phenetyl ester (CAPE) from a topical mucoadhesive gel containing propolis.
Topics: Adhesiveness; Administration, Topical; Animals; Anti-Inflammatory Agents; Caffeic Acids; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Gels; Humans; Male; Mouth Mucosa; Permeability; Phenylethyl Alcohol; Phytotherapy; Propolis; Stomatitis; Swine; Time Factors | 2002 |
Phytochemical compounds involved in the anti-inflammatory effect of propolis extract.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis; Caffeic Acids; Carrageenan; Cell Division; Chronic Disease; Edema; Flavonoids; Male; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Pleurisy; Propolis; Rats; Rats, Inbred Lew; Rats, Wistar; T-Lymphocytes; Time Factors | 2002 |
NF-kappaB activation is essential for angiotensin II-dependent proliferation and migration of vascular smooth muscle cells.
Topics: Angioplasty, Balloon, Coronary; Angiotensin II; Animals; Anti-Infective Agents; Caffeic Acids; Cell Division; Cell Movement; Heart; Muscle, Smooth, Vascular; NF-kappa B; Nitriles; Organ Culture Techniques; Phenylethyl Alcohol; Phosphorylation; Receptors, Angiotensin; Sulfones; Sus scrofa | 2002 |
Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element.
Topics: Animals; Antioxidants; Blotting, Western; Caffeic Acids; Carrier Proteins; Curcumin; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); LLC-PK1 Cells; NF-E2-Related Factor 2; Phenylethyl Alcohol; Promoter Regions, Genetic; Trans-Activators | 2003 |
Caffeic acid phenethyl ester (CAPE) analogues: potent nitric oxide inhibitors from the Netherlands propolis.
Topics: Animals; Caffeic Acids; Cell Line; Macrophages; Mice; Netherlands; Nitric Oxide; Phenylethyl Alcohol; Propolis | 2003 |
Chlamydophila pneumoniae induces ICAM-1 expression in human aortic endothelial cells via protein kinase C-dependent activation of nuclear factor-kappaB.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aorta; Caffeic Acids; Cell Membrane; Cells, Cultured; Chlamydophila Infections; Chlamydophila pneumoniae; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Humans; Immunoblotting; Intercellular Adhesion Molecule-1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Phenylethyl Alcohol; Protein Kinase C; RNA, Messenger; Signal Transduction; Sulfones; Up-Regulation | 2003 |
Vascular effects of caffeic acid phenethyl ester (CAPE) on isolated rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Caffeic Acids; Calcium; Cytosol; Enzyme Inhibitors; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Phenylethyl Alcohol; Potassium Chloride; Rats; Rats, Wistar; Vasoconstrictor Agents | 2003 |
Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Caffeic Acids; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Phenylethyl Alcohol; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2003 |
Effect of caffeic acid phenethyl ester on proliferation and apoptosis of hepatic stellate cells in vitro.
Topics: Animals; Apoptosis; Caffeic Acids; Cell Division; Cells, Cultured; Liver; Male; Phenylethyl Alcohol; Rats; Rats, Wistar | 2003 |
Effect of propolis on human cartilage and chondrocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Cartilage; Cartilage, Articular; Cell Separation; Cells, Cultured; Chondrocytes; Glycosaminoglycans; Humans; Indomethacin; Nitric Oxide; Nitrites; Organ Culture Techniques; Phenylethyl Alcohol; Propolis | 2003 |
Caffeic acid phenethyl ester (CAPE) prevents inflammatory stress in organotypic hippocampal slice cultures.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Caenorhabditis elegans Proteins; Caffeic Acids; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Hippocampus; Immunohistochemistry; Inflammation; Interferon-gamma; Lipopolysaccharides; NF-kappa B; Nitrites; Organ Culture Techniques; Phenylethyl Alcohol; Rats; Rats, Wistar; Stress, Physiological; Tumor Necrosis Factor-alpha | 2003 |
The effects of caffeic acid phenethyl ester on tissue damage in lung after hindlimb ischemia-reperfusion.
Topics: Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Caffeic Acids; Capillary Permeability; Hindlimb; Injections, Intraperitoneal; Lung; Male; Malondialdehyde; Neutrophil Infiltration; Peroxidase; Phenylethyl Alcohol; Proteins; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Sodium-Potassium-Exchanging ATPase; Time Factors; Tourniquets; Turkey | 2003 |
Effects of caffeic acid phenethyl ester and alpha-tocopherol on reperfusion injury in rat brain.
Topics: Adenosine Deaminase; alpha-Tocopherol; Animals; Brain; Brain Chemistry; Caffeic Acids; Catalase; Data Interpretation, Statistical; Glutathione Peroxidase; Heart; Male; Malondialdehyde; Myocardium; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Statistics, Nonparametric; Superoxide Dismutase; Xanthine Oxidase | 2003 |
Regulation of microglial inflammatory response by histone deacetylase inhibitors.
Topics: Animals; Caffeic Acids; Cells, Cultured; Coculture Techniques; DNA; Drug Synergism; Enzyme Inhibitors; Hippocampus; Histone Deacetylase Inhibitors; Inflammation; Interleukin-6; Lipopolysaccharides; Mice; Microglia; Neurons; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Rats; Rats, Wistar; RNA, Messenger; Sesquiterpenes; Sesquiterpenes, Guaiane | 2003 |
Caffeic acid phenethyl ester blocks apoptosis induced by low potassium in cerebellar granule cells.
Topics: Animals; Animals, Newborn; Apoptosis; Caffeic Acids; Caspase 3; Caspase 9; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Cerebellum; Culture Media; Neurons; NF-kappa B; Phenylethyl Alcohol; Potassium; Rats; Rats, Wistar; Reactive Oxygen Species | 2003 |
Caffeic acid phenethyl ester inhibits T-cell activation by targeting both nuclear factor of activated T-cells and NF-kappaB transcription factors.
Topics: Caffeic Acids; Cell Cycle; Cell Division; DNA-Binding Proteins; Humans; Interleukin-2; Jurkat Cells; Lymphocyte Activation; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Phenylethyl Alcohol; Phosphorylation; Promoter Regions, Genetic; T-Lymphocytes; Transcription Factors; Transcriptional Activation | 2004 |
Caffeic acid phenethyl ester induces apoptosis by inhibition of NFkappaB and activation of Fas in human breast cancer MCF-7 cells.
Topics: Adenoviridae; Apoptosis; Arabidopsis Proteins; bcl-2-Associated X Protein; Caffeic Acids; Caspase 8; Caspase 9; Caspases; Cell Line, Tumor; Cell Nucleus; Cross-Linking Reagents; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; fas Receptor; Fatty Acid Desaturases; Genes, Dominant; Genes, Reporter; Genetic Vectors; Humans; I-kappa B Proteins; Immunoblotting; K562 Cells; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Signal Transduction; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2004 |
Involvement of tumor suppressor protein p53 and p38 MAPK in caffeic acid phenethyl ester-induced apoptosis of C6 glioma cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caffeic Acids; Caspase 3; Caspases; Cytochromes c; Glioma; Imidazoles; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Serine; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
Propolin C from propolis induces apoptosis through activating caspases, Bid and cytochrome c release in human melanoma cells.
Topics: Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Caffeic Acids; Carrier Proteins; Caspases; Cell Cycle; Cell Division; Cell Survival; Cytochromes c; DNA Fragmentation; Enzyme Activation; Flavonoids; Free Radicals; Humans; Melanoma; Mitochondria; Phenylethyl Alcohol; Propolis; Xanthine Oxidase | 2004 |
Role of curcumin and the inhibition of NF-kappaB in the onset of chemotherapy-induced mucosal barrier injury.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line; Curcumin; Cytarabine; Drug Interactions; Female; Intestinal Mucosa; Methotrexate; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Inbred Strains | 2004 |
Protective role of alpha-tocopherol and caffeic acid phenethyl ester on ischemia-reperfusion injury via nitric oxide and myeloperoxidase in rat kidneys.
Topics: alpha-Tocopherol; Animals; Antioxidants; Caffeic Acids; Catalase; Kidney; Nitric Oxide; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase | 2004 |
Inhibitory effect of caffeic acid phenethyl ester on bleomycine-induced lung fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Caffeic Acids; Catalase; Hydroxyproline; Lung; Male; Malondialdehyde; Molecular Structure; Nitric Oxide; Organ Size; Peroxidase; Phenylethyl Alcohol; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vitamin E | 2004 |
Inhibitory effect of caffeic acid phenethyl ester on angiogenesis, tumor invasion, and metastasis.
Topics: Adenocarcinoma; Animals; Caffeic Acids; Cell Division; Cell Survival; Colonic Neoplasms; Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Phenylethyl Alcohol; Umbilical Veins; Vascular Endothelial Growth Factor A | 2003 |
Sulindac sulfide and caffeic acid phenethyl ester suppress the motility of lung adenocarcinoma cells promoted by transforming growth factor-beta through Akt inhibition.
Topics: Adenocarcinoma; Antineoplastic Agents; Caffeic Acids; Catechin; Cell Movement; Curcumin; Humans; Lung Neoplasms; Neovascularization, Pathologic; NF-kappa B; Phenylethyl Alcohol; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sulindac; Transforming Growth Factor beta; Tumor Cells, Cultured | 2004 |
Chemoprotective effect of caffeic acid phenethyl ester on promotion in a medium-term rat hepatocarcinogenesis assay.
Topics: Animals; Blotting, Western; Caffeic Acids; Carcinoma, Hepatocellular; Cell Nucleus; Disease Models, Animal; Disease Progression; gamma-Glutamyltransferase; Gene Expression Regulation; Glutathione S-Transferase pi; Glutathione Transferase; Humans; I-kappa B Proteins; Isoenzymes; Liver Neoplasms, Experimental; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Precancerous Conditions; Protein Transport; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Interleukin-1beta induces macrophage inflammatory protein-1beta expression in human hepatocytes.
Topics: Caffeic Acids; Cell Line, Tumor; Chemokine CCL4; Gene Expression Regulation; Hepatocytes; Humans; Interleukin-1; Macrophage Inflammatory Proteins; Macrophages; NF-kappa B; Phenylethyl Alcohol; Promoter Regions, Genetic; Receptors, CCR5 | 2003 |
Acute induction of inflammatory cytokine expression after gamma-irradiation in the rat: effect of an NF-kappaB inhibitor.
Topics: Animals; Caffeic Acids; Enteritis; Gamma Rays; Ileum; Interleukin-1; Interleukin-10; Interleukin-6; Interleukin-8; Interleukins; Male; Muscle, Smooth; NF-kappa B; Phenylethyl Alcohol; Radiation Injuries; Rats; Rats, Wistar; Receptors, Interleukin-6; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Time Factors; Transcription Factors; Tumor Necrosis Factor-alpha; Whole-Body Irradiation | 2004 |
The effect of CAPE on lipid peroxidation and nitric oxide levels in the plasma of rats following thermal injury.
Topics: Animals; Antioxidants; Burns; Caffeic Acids; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Xanthine Oxidase | 2004 |
Native LDL induces interleukin-8 expression via H2O2, p38 Kinase, and activator protein-1 in human aortic smooth muscle cells.
Topics: Aorta; Caffeic Acids; Cells, Cultured; Coronary Vessels; Dactinomycin; Dose-Response Relationship, Drug; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Interleukin-8; Lipoproteins, LDL; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Pyridines; Sesquiterpenes; Time Factors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2004 |
Immunomodulatory effect of caffeic acid phenethyl ester in Balb/c mice.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Body Weight; Caffeic Acids; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Female; Flow Cytometry; Immunoglobulin M; Immunophenotyping; Mice; Mice, Inbred BALB C; Mitogens; Organ Size; Phenylethyl Alcohol; Spleen; Thymus Gland | 2004 |
Stimulatory actions of caffeic acid phenethyl ester, a known inhibitor of NF-kappaB activation, on Ca2+-activated K+ current in pituitary GH3 cells.
Topics: Amidines; Animals; Caffeic Acids; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Electric Conductivity; Ion Channel Gating; Masoprocol; Membrane Potentials; NF-kappa B; Patch-Clamp Techniques; Phenylethyl Alcohol; Pituitary Gland; Potassium Channels, Calcium-Activated; Rats; Riluzole; tert-Butylhydroperoxide | 2004 |
Stage-dependent modulation of limb regeneration by caffeic acid phenethyl ester (CAPE)--immunocytochemical evidence of a CAPE-evoked delay in mesenchyme formation and limb regeneration.
Topics: Analysis of Variance; Animals; Autoradiography; Caffeic Acids; Extremities; Immunoenzyme Techniques; Immunohistochemistry; Keratinocytes; Mesoderm; Phenylethyl Alcohol; Regeneration; Salamandridae; Thymidine; Tritium; Vimentin; Wound Healing | 2004 |
Use of caffeic acid phenethyl ester and cortisone may prevent proliferative vitreoretinopathy.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cortisone; Female; Glutathione; Male; Nitrites; Phenylethyl Alcohol; Rabbits; Retina; Vitreoretinopathy, Proliferative; Vitreous Body | 2004 |
Protective effects of caffeic acid phenethyl ester against experimental allergic encephalomyelitis-induced oxidative stress in rats.
Topics: Animals; Biomarkers; Brain; Caffeic Acids; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Spinal Cord | 2004 |
Caffeic acid phenethyl ester-induced PC-3 cell apoptosis is caspase-dependent and mediated through the loss of inhibitors of apoptosis proteins.
Topics: Apoptosis; Blotting, Western; Caffeic Acids; Caspase Inhibitors; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Male; NF-kappa B; Paclitaxel; Phenylethyl Alcohol; Prostatic Neoplasms; Tumor Necrosis Factor-alpha | 2004 |
Reduction of ischemia--reperfusion induced myocardial infarct size in rats by caffeic acid phenethyl ester (CAPE).
Topics: Animals; Antioxidants; Caffeic Acids; Free Radicals; Lipoxygenase; Male; Myocardial Infarction; Myocardium; Neutrophils; Oxidative Stress; Oxygen; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Xanthine Oxidase | 2004 |
Cell killing and radiosensitization by caffeic acid phenethyl ester (CAPE) in lung cancer cells.
Topics: Adenocarcinoma; Apoptosis; Caffeic Acids; Cell Line; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Lung Neoplasms; Phenylethyl Alcohol; Radiation Tolerance; Radiation-Sensitizing Agents | 2004 |
Caffeic acid phenethyl ester ameliorated ototoxicity induced by cisplatin in rats.
Topics: Analysis of Variance; Animals; Caffeic Acids; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Hearing Loss, Sensorineural; Otoacoustic Emissions, Spontaneous; Phenylethyl Alcohol; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric | 2004 |
Quantitative analysis of caffeic acid phenethyl ester in crude propolis by liquid chromatography-electrospray ionization mass spectrometry.
Topics: Caffeic Acids; Chromatography, Liquid; Cytotoxins; Indicators and Reagents; Phenylethyl Alcohol; Propolis; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2004 |
Protective effects of caffeic acid phenethyl ester (CAPE) on carbon tetrachloride-induced hepatotoxicity in rats.
Topics: Animals; Caffeic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytotoxins; Drug Therapy, Combination; Liver; Liver Cirrhosis; Liver Function Tests; Male; Phenylethyl Alcohol; Rats; Rats, Wistar | 2004 |
[The nitrosative effect of peripheral ischemia-reperfusion on lung and preventive of caffeic acid phenethyl ester].
Topics: Animals; Bronchoalveolar Lavage Fluid; Caffeic Acids; Capillary Permeability; Cytokines; Hindlimb; Lung; Male; Malondialdehyde; Neutrophil Infiltration; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Tourniquets; Tyrosine | 2004 |
Development and validation of a liquid chromatographic-tandem mass spectrometric method for the determination of caffeic acid phenethyl ester in rat plasma and urine.
Topics: Animals; Caffeic Acids; Chromatography, High Pressure Liquid; Glucuronidase; Glucuronides; Male; Phenylethyl Alcohol; Rats; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2004 |
Caffeic acid phenethyl ester as a protective agent against doxorubicin nephrotoxicity in rats.
Topics: Animals; Antioxidants; Caffeic Acids; Doxorubicin; Drug Interactions; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Nitric Oxide; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley | 2004 |
Co-operative functions between nuclear factors NFkappaB and CCAT/enhancer-binding protein-beta (C/EBP-beta) regulate the IL-6 promoter in autocrine human prostate cancer cells.
Topics: Base Sequence; Binding Sites; Blotting, Western; Caffeic Acids; CCAAT-Enhancer-Binding Protein-beta; DNA; Gene Expression Regulation; Humans; I-kappa B Proteins; Immunohistochemistry; Interleukin-6; Male; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2004 |
Interleukin-1beta upregulates functional expression of neurokinin-1 receptor (NK-1R) via NF-kappaB in astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Biphenyl Compounds; Caffeic Acids; Calcium; Calcium Signaling; Cell Line, Tumor; Cells, Cultured; Central Nervous System; Cytosol; Encephalitis; Gene Expression Regulation; Humans; Interleukin-1; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Up-Regulation | 2004 |
Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2004 |
Caffeic acid phenethyl ester prevents neonatal hypoxic-ischaemic brain injury.
Topics: Animals; Animals, Newborn; Caffeic Acids; Calcium; Caspase 3; Caspases; Cells, Cultured; Cytochromes c; Drug Evaluation, Preclinical; Enzyme Activation; Hypoxia-Ischemia, Brain; Mitochondria; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2004 |
Effects of caffeic acid phenethyl ester on glycerol-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Antioxidants; Caffeic Acids; Glycerol; Injections, Intramuscular; Kidney; Lipid Peroxidation; Male; Myoglobinuria; Necrosis; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar | 2004 |
Oral flavonoid supplementation attenuates atherosclerosis development in apolipoprotein E-deficient mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aorta, Thoracic; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Caffeic Acids; Cell Adhesion Molecules; Cytokines; Depression, Chemical; Drug Evaluation, Preclinical; Extracellular Matrix Proteins; Free Radical Scavengers; Gene Expression Profiling; Gene Expression Regulation; Hyperlipoproteinemia Type II; Isoprostanes; Lipids; Male; Mice; Mice, Knockout; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Transcription Factors | 2005 |
Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Humans; Liver Neoplasms; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Neoplasm Metastasis; NF-kappa B; Phenylethyl Alcohol; Transcription, Genetic | 2004 |
Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells.
Topics: Animals; Aurintricarboxylic Acid; Caffeic Acids; Cattle; Cell Survival; Chalcone; Chalcones; Curcumin; Endothelial Cells; Enzyme Activation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Mitogen-Activated Protein Kinases; Oxidative Stress; Phenylethyl Alcohol | 2005 |
The protective effect of caffeic acid phenethyl ester on ischemia-reperfusion injury in rat ovary.
Topics: Animals; Antioxidants; Caffeic Acids; Female; Lipid Peroxidation; Models, Animal; Ovarian Diseases; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Torsion Abnormality | 2004 |
Caffeic acid phenethyl ester improves oxidative organ damage in rat model of thermal trauma.
Topics: Animals; Burns; Caffeic Acids; Disease Models, Animal; Injections, Intraperitoneal; Kidney Diseases; Lung Diseases; Male; Malondialdehyde; Multiple Organ Failure; Oxidoreductases; Phenylethyl Alcohol; Rats; Rats, Wistar; Treatment Outcome | 2004 |
Protective role of caffeic acid phenethyl ester (cape) on gentamicin-induced acute renal toxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Caffeic Acids; Catalase; Female; Free Radical Scavengers; Gentamicins; Glutathione; Kidney; Kidney Tubular Necrosis, Acute; Malondialdehyde; Medicine, Traditional; Nitric Oxide; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase | 2005 |
Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart.
Topics: Animals; Antioxidants; Caffeic Acids; Diabetes Mellitus, Experimental; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Oxidative Stress; Oxidoreductases; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2005 |
Inhibition of cyclooxygenase-2 expression and restoration of gap junction intercellular communication in H-ras-transformed rat liver epithelial cells by caffeic acid phenethyl ester.
Topics: Animals; Base Sequence; Blotting, Western; Caffeic Acids; Cell Communication; Cell Line, Transformed; Cyclooxygenase 2; DNA Primers; DNA Probes; Electrophoretic Mobility Shift Assay; Gap Junctions; Genes, ras; Liver; Phenylethyl Alcohol; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Rats | 2004 |
Caffeic acid phenethyl ester exerts a neuroprotective effect on CNS against pentylenetetrazol-induced seizures in mice.
Topics: Animals; Antioxidants; Biomarkers; Caffeic Acids; Central Nervous System; Convulsants; Female; Malondialdehyde; Mice; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Oxidants; Oxidative Stress; Pentylenetetrazole; Phenylethyl Alcohol; Reactive Oxygen Species; Seizures; Superoxide Dismutase; Xanthine Oxidase | 2004 |
Interference of arachidonic acid and its metabolites with TNF-alpha release by ochratoxin A from rat liver.
Topics: Animals; Arachidonic Acid; Aristolochic Acids; Caffeic Acids; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Liver; Male; NF-kappa B; Ochratoxins; Phenylethyl Alcohol; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Caffeic acid phenethyl ester protects kidneys against carbon tetrachloride toxicity in rats.
Topics: Animals; Caffeic Acids; Carbon Tetrachloride Poisoning; Creatinine; Kidney; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Wistar; Urea | 2005 |
Chlorogenate hydrolase-catalyzed synthesis of hydroxycinnamic acid ester derivatives by transesterification, substitution of bromine, and condensation reactions.
Topics: Aspergillus; Bromine; Caffeic Acids; Chlorogenic Acid; Coumaric Acids; Esterification; Esters; Ethylene Dibromide; Hydrogen-Ion Concentration; Hydrolases; Phenylethyl Alcohol | 2005 |
Protective effect of caffeic acid phenethyl ester (CAPE) on myocardial ischemia-reperfusion-induced apoptotic cell death.
Topics: Animals; Apoptosis; Caffeic Acids; Cell Death; Cytoprotection; Free Radical Scavengers; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phenylethyl Alcohol; Rats; Rats, Wistar | 2005 |
[Xanthine oxidase inhibitory activity and hypouricemia effect of propolis in rats].
Topics: Animals; Anti-Infective Agents; Brazil; Caffeic Acids; China; Coumaric Acids; Disease Models, Animal; Flavonoids; Gout; Hyperuricemia; Male; Oxonic Acid; Phenylethyl Alcohol; Phenylpropionates; Propionates; Propolis; Rats; Rats, Sprague-Dawley; Uric Acid; Xanthine Oxidase | 2005 |
Gentamicin-induced nephrotoxicity and protective effect of caffeic acid phenethyl ester in rats.
Topics: Animals; Anti-Bacterial Agents; Caffeic Acids; Female; Gentamicins; Lipid Peroxidation; Nephrosis; Phenylethyl Alcohol; Rats; Rats, Wistar | 2005 |
Properties of BK(Ca) channels in oral keratinocytes.
Topics: Apamin; Caffeic Acids; Carcinoma, Squamous Cell; Cell Line, Tumor; Cells, Cultured; Decanoic Acids; Electrochemistry; Humans; Hydroxy Acids; Indoles; Ion Transport; Keratinocytes; Mouth Mucosa; Mouth Neoplasms; NF-kappa B; Patch-Clamp Techniques; Peptides; Phenylethyl Alcohol; Potassium; Potassium Channel Blockers; Potassium Channels, Calcium-Activated | 2005 |
A novel antioxidant agent caffeic acid phenethyl ester prevents shock wave-induced renal tubular oxidative stress.
Topics: Acetylglucosaminidase; Animals; Antioxidants; Caffeic Acids; Kidney Tubules; Lithotripsy; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rabbits | 2005 |
Inhibitory effect of caffeic acid phenethyl ester on the growth of C6 glioma cells in vitro and in vivo.
Topics: Animals; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Glioma; Immunoblotting; Immunohistochemistry; In Vitro Techniques; Mice; Neoplasms, Experimental; Phenylethyl Alcohol; Rats; Retinoblastoma Protein | 2006 |
Cytotoxicity of phenolic acid phenethyl esters on oral cancer cells.
Topics: Caffeic Acids; Carcinoma, Squamous Cell; Cell Line, Tumor; Humans; Hydroxybenzoates; Phenylethyl Alcohol; Structure-Activity Relationship; Tongue Neoplasms | 2005 |
Caffeic acid phenethyl ester (CAPE) supplemented St. Thomas' hospital cardioplegic solution improves the antioxidant defense system of rat myocardium during ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Caffeic Acids; Cardioplegic Solutions; Catalase; Free Radical Scavengers; Heart; In Vitro Techniques; Male; Malondialdehyde; Myocardial Reperfusion Injury; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tyrosine | 2005 |
Effects of melatonin and caffeic acid phenethyl ester on testicular injury induced by myocardial ischemia/reperfusion in rats.
Topics: Animals; Antioxidants; Atrophy; Blood Pressure; Caffeic Acids; Free Radicals; Male; Malondialdehyde; Melatonin; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Testicular Diseases; Testis | 2005 |
Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway.
Topics: Animals; Blotting, Western; Brain; Caffeic Acids; Capillary Permeability; Cattle; Cells, Cultured; Dextrans; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; NF-kappa B; Nitriles; Oncogene Proteins v-rel; Phenylethyl Alcohol; Proline; Signal Transduction; Sulfones; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Effects of caffeic acid phenethyl ester on lipopolysaccharide-induced lung injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Lipopolysaccharides; Lung; Male; Malondialdehyde; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Respiratory Distress Syndrome; Sodium-Potassium-Exchanging ATPase | 2006 |
The protective effect of caffeic acid phenethyl ester against cyclosporine A-induced cardiotoxicity in rats.
Topics: Animals; Caffeic Acids; Cyclosporine; Electron Transport Complex IV; Heart Diseases; Immunosuppressive Agents; Male; Matrix Metalloproteinase 2; Myocardium; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Tissue Inhibitor of Metalloproteinase-2 | 2005 |
Neoflavonoids and related constituents from Nepalese propolis and their nitric oxide production inhibitory activity.
Topics: Caffeic Acids; Flavonoids; Inhibitory Concentration 50; Lipopolysaccharides; Macrophages; Molecular Structure; Nepal; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; omega-N-Methylarginine; Phenylethyl Alcohol; Propolis | 2005 |
The activities of liver adenosine deaminase, xanthine oxidase, catalase, superoxide dismutase enzymes and the levels of malondialdehyde and nitric oxide after cisplatin toxicity in rats: protective effect of caffeic acid phenethyl ester.
Topics: Adenosine Deaminase; Animals; Antineoplastic Agents; Caffeic Acids; Catalase; Cisplatin; Liver; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Protective Agents; Rats; Superoxide Dismutase; Xanthine Oxidase | 2005 |
Myocardial ischemia/reperfusion-induced oxidative renal damage in rats: protection by caffeic acid phenethyl ester (CAPE).
Topics: Animals; Caffeic Acids; Kidney Diseases; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar | 2005 |
Effects of CAPE-like compounds on HIV replication in vitro and modulation of cytokines in vivo.
Topics: Animals; Anti-HIV Agents; Caffeic Acids; Cell Survival; Cytokines; Female; HIV-1; Humans; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; Molecular Structure; Phenylethyl Alcohol; Virus Replication | 2005 |
Caffeic acid phenyl ester in propolis is a strong inhibitor of matrix metalloproteinase-9 and invasion inhibitor: isolation and identification.
Topics: Animals; Caffeic Acids; Cell Movement; Cell Survival; Cells, Cultured; Humans; Liver Neoplasms; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Molecular Structure; Neoplasm Invasiveness; Phenylethyl Alcohol; Propolis | 2005 |
Ischemia-reperfusion leads to depletion of glutathione content and augmentation of malondialdehyde production in the rat heart from overproduction of oxidants: can caffeic acid phenethyl ester (CAPE) protect the heart?
Topics: Animals; Antioxidants; Caffeic Acids; Cardiotonic Agents; Free Radicals; Glutathione; Heart; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; NF-kappa B; Oxidative Stress; Oxygen; Phenylethyl Alcohol; Rats; Rats, Wistar | 2005 |
Oleic acid-induced lung injury in rats and effects of caffeic acid phenethyl ester.
Topics: Animals; Bronchoalveolar Lavage Fluid; Caffeic Acids; Female; Lung; Lung Diseases; Malondialdehyde; Oleic Acid; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2005 |
Role of nitric oxide in regulating secreted phospholipase A2 release from astrocytes.
Topics: Analysis of Variance; Animals; Astrocytes; Blotting, Western; Caffeic Acids; Cells, Cultured; Cerebral Cortex; Chelating Agents; Drug Interactions; Edetic Acid; Embryo, Mammalian; Enzyme Inhibitors; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Phenylethyl Alcohol; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Caffeic acid phenethyl ester (CAPE) prevents transformation of human cells by arsenite (As) and suppresses growth of As-transformed cells.
Topics: Antioxidants; Apoptosis; Arsenites; Caffeic Acids; Catechin; Cell Growth Processes; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cytokines; Drug Interactions; Flow Cytometry; Humans; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Phenylethyl Alcohol; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2005 |
Antiarrhythmic effect of caffeic acid phenethyl ester (CAPE) on myocardial ischemia/reperfusion injury in rats.
Topics: Animals; Anti-Arrhythmia Agents; Caffeic Acids; Male; Myocardial Reperfusion Injury; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Tachycardia, Ventricular; Ventricular Fibrillation | 2005 |
Comparative analysis of the protective effects of melatonin and caffeic acid phenethyl ester (CAPE) on mobile phone-induced renal impairment in rat.
Topics: Acetylglucosaminidase; Animals; Antioxidants; Caffeic Acids; Catalase; Cell Phone; Electromagnetic Fields; Glutathione Peroxidase; Kidney; Male; Malondialdehyde; Melatonin; Models, Animal; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2005 |
A novel antioxidant agent caffeic acid phenethyl ester prevents long-term mobile phone exposure-induced renal impairment in rat. Prognostic value of malondialdehyde, N-acetyl-beta-D-glucosaminidase and nitric oxide determination.
Topics: Acetylglucosaminidase; Animals; Antioxidants; Caffeic Acids; Cell Phone; Electromagnetic Fields; Kidney; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Prognosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2005 |
Lithium-induced renal toxicity in rats: protection by a novel antioxidant caffeic acid phenethyl ester.
Topics: Acetylglucosaminidase; Animals; Antioxidants; Blood Urea Nitrogen; Caffeic Acids; Catalase; Creatinine; Glutathione Peroxidase; Kidney; Lithium; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2005 |
The activities of purine-catabolizing enzymes and the level of nitric oxide in rat kidneys subjected to methotrexate: protective effect of caffeic acid phenethyl ester.
Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Caffeic Acids; Folic Acid Antagonists; Free Radical Scavengers; Kidney; Male; Methotrexate; Nitric Oxide; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Xanthine Oxidase | 2005 |
Effects of caffeic acid phenethyl ester on endotoxin-induced uveitis in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aqueous Humor; Caffeic Acids; Ciliary Body; Disease Models, Animal; Eye Proteins; Injections, Intraperitoneal; Iris; Lipopolysaccharides; Male; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Salmonella typhimurium; Uveitis | 2005 |
Antiproliferation and radiosensitization of caffeic acid phenethyl ester on human medulloblastoma cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Astrocytes; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Cerebellar Neoplasms; Cisplatin; DNA Fragmentation; Doxorubicin; Drug Synergism; Humans; In Situ Nick-End Labeling; Medulloblastoma; Phenylethyl Alcohol; Radiation-Sensitizing Agents; Tumor Stem Cell Assay | 2006 |
Effect of caffeic acid phenethyl ester on gastric acid secretion in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholinesterase; Animals; Caffeic Acids; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Gastrointestinal Agents; Histamine; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscarine; Nifedipine; Pentagastrin; Phenylethyl Alcohol; Physostigmine; Potassium; Stomach | 2005 |
The selective inhibition of nitric oxide production in the avian macrophage cell line HD11.
Topics: Animals; Caffeic Acids; Cell Line; Chickens; Enterococcus; Enzyme Inhibitors; Genistein; I-kappa B Proteins; Klebsiella pneumoniae; Leupeptins; Macrophage Activation; Macrophages; NF-kappa B; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Poly I-C; Poultry Diseases; Protein-Tyrosine Kinases; RNA, Double-Stranded; Signal Transduction | 2006 |
Inhibitory effects of caffeic acid phenethyl ester on cancer cell metastasis mediated by the down-regulation of matrix metalloproteinase expression in human HT1080 fibrosarcoma cells.
Topics: Caffeic Acids; Cell Line, Tumor; Fibrosarcoma; Gene Expression Regulation, Enzymologic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Matrix Metalloproteinases, Membrane-Associated; Neoplasm Metastasis; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2 | 2006 |
Caffeic acid phenethyl ester possesses potent cardioprotective effects in a rabbit model of acute myocardial ischemia-reperfusion injury.
Topics: Acute Disease; Animals; Apoptosis; Blotting, Western; Caffeic Acids; Cardiotonic Agents; Caspases; Creatine Kinase; Cytochromes c; In Situ Nick-End Labeling; Inflammation; Interleukin-1; L-Lactate Dehydrogenase; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Rabbits; Rats; Rats, Sprague-Dawley; Troponin I; Tumor Necrosis Factor-alpha | 2005 |
Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells.
Topics: Active Transport, Cell Nucleus; Anti-Inflammatory Agents; Caffeic Acids; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclooxygenase 2; Cytokines; DNA; Dose-Response Relationship, Drug; Epithelial Cells; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; I-kappa B Proteins; Membrane Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Time Factors; Transcription Factor AP-1; Transcription Factor RelA; Transcription, Genetic | 2005 |
Caffeic acid phenethyl ester preferentially sensitizes CT26 colorectal adenocarcinoma to ionizing radiation without affecting bone marrow radioresponse.
Topics: Adenocarcinoma; Animals; Bone Marrow; Caffeic Acids; Cell Cycle; Colorectal Neoplasms; DNA Repair; Drug Evaluation, Preclinical; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Mice; Mice, Inbred BALB C; NF-kappa B; Phenylethyl Alcohol; Radiation-Sensitizing Agents | 2005 |
In vivo effects of caffeic acid phenethyl ester on myocardial ischemia-reperfusion injury and apoptotic changes in rats.
Topics: Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Caffeic Acids; Cell Count; Coronary Disease; Creatine Kinase; Disease Models, Animal; Glutathione; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar | 2005 |
Caffeic acid phenethyl ester ameliorates changes in IGFs secretion and gene expression in streptozotocin-induced diabetic rats.
Topics: Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Gene Expression; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Kidney; Liver; Male; Myocardium; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
Caffeic acid phenethyl ester ameliorates cerebral infarction in rats subjected to focal cerebral ischemia.
Topics: Animals; Antioxidants; Blood Flow Velocity; Brain; Brain Ischemia; Caffeic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Long-Evans; Reperfusion Injury | 2006 |
Protective effects of melatonin and caffeic acid phenethyl ester against retinal oxidative stress in long-term use of mobile phone: a comparative study.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Cell Phone; Electromagnetic Fields; Free Radical Scavengers; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Retina; Superoxide Dismutase | 2006 |
The activity of adenosine deaminase and the level of nitric oxide in spinal cord of methotrexate administered rats: protective effect of caffeic acid phenethyl ester.
Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antioxidants; Antirheumatic Agents; Caffeic Acids; Male; Methotrexate; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Spinal Cord | 2006 |
Caffeic acid phenethyl ester decreases acute pneumonitis after irradiation in vitro and in vivo.
Topics: Animals; Antioxidants; Caffeic Acids; Fibroblasts; Humans; Inflammation; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Radiation Pneumonitis; Tumor Cells, Cultured | 2005 |
Mobile phone-induced myocardial oxidative stress: protection by a novel antioxidant agent caffeic acid phenethyl ester.
Topics: Animals; Antioxidants; Caffeic Acids; Cell Phone; Heart; Male; Myocardium; Oxidative Stress; Phenylethyl Alcohol; Radiation Injuries, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2005 |
Role of vagal activity on bradicardic and hypotensive effects of caffeic acid phenethyl ester (CAPE).
Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Bradycardia; Caffeic Acids; Disease Models, Animal; Male; Muscarinic Antagonists; Parasympathetic Nervous System; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Vagotomy; Vagus Nerve | 2005 |
Caffeic acid phenethyl ester (CAPE) attenuates cerebral vasospasm after experimental subarachnoidal haemorrhage by increasing brain nitric oxide levels.
Topics: Animals; Basilar Artery; Brain; Caffeic Acids; Free Radical Scavengers; Glutathione; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2006 |
Altered iron homeostasis involvement in arsenite-mediated cell transformation.
Topics: Antioxidants; Arsenites; Caffeic Acids; Cell Transformation, Neoplastic; Cytoplasm; Ferritins; Homeostasis; Humans; Iron; Iron-Regulatory Proteins; Osteosarcoma; Oxidative Stress; Phenylethyl Alcohol; Receptors, Transferrin; Tumor Cells, Cultured | 2006 |
Direct and indirect mechanism(s) of antitumour activity of propolis and its polyphenolic compounds.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; DNA; Female; Femur; HeLa Cells; Humans; Leukocyte Count; Macrophage Activation; Male; Mice; Mice, Inbred CBA; Mitogens; Nitric Oxide; Phenylethyl Alcohol; Propolis; Spleen | 2006 |
Lithium-induced lung toxicity in rats: the effect of caffeic acid phenethyl ester (CAPE).
Topics: Animals; Antioxidants; Caffeic Acids; Cell Movement; Injections, Intraperitoneal; Lithium; Lung; Lung Diseases; Lymphocytes; Macrophages, Alveolar; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar | 2006 |
Oxidative stress in testicular tissues of rats exposed to cigarette smoke and protective effects of caffeic acid phenethyl ester.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Glutathione Peroxidase; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Smoking; Superoxide Dismutase; Testis | 2006 |
Does propofol or caffeic acid phenethyl ester prevent lung injury after hindlimb ischaemia-reperfusion in ventilated rats?
Topics: Animals; Caffeic Acids; Free Radical Scavengers; Hindlimb; Ischemia; Lung; Lung Diseases; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Positive-Pressure Respiration; Propofol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome | 2006 |
Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis.
Topics: Apoptosis; Blotting, Western; Caffeic Acids; Caspase 3; Caspase 8; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Breaks; DNA Fragmentation; DNA, Circular; Dose-Response Relationship, Drug; Flavonoids; Flow Cytometry; HL-60 Cells; Humans; Melanoma; Mitochondria; Molecular Structure; Phenylethyl Alcohol; Propolis; Reactive Oxygen Species; Signal Transduction; Xanthine Oxidase | 2007 |
Effect of caffeic acid phenethyl ester on survival of axial pattern flaps in rats with ischaemia-reperfusion injuries.
Topics: Animals; Antioxidants; Caffeic Acids; Graft Survival; Male; Nitrates; Nitrites; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Surgical Flaps | 2006 |
Cytoprotective effect of caffeic acid phenethyl ester (CAPE) and catechol ring-fluorinated CAPE derivatives against menadione-induced oxidative stress in human endothelial cells.
Topics: Antioxidants; Caffeic Acids; Cells, Cultured; Cytoprotection; Drug Evaluation, Preclinical; Endothelial Cells; Fluorine; Humans; Oxidative Stress; Phenylethyl Alcohol; Structure-Activity Relationship; Vitamin K 3 | 2006 |
The effect of caffeic acid phenethyl ester on short-term acute myocardial ischemia.
Topics: Acute Disease; Adenosine Deaminase; Animals; Antioxidants; Caffeic Acids; Cardiotonic Agents; Catalase; Glutathione Peroxidase; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase; Xanthine Oxidase | 2006 |
Protective role of caffeic acid phenethyl ester in the liver of rats exposed to cold stress.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Cold Temperature; Female; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Malondialdehyde; Necrosis; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Stress, Physiological; Superoxide Dismutase | 2006 |
Caffeic acid phenethyl ester blocks free radical generation and 6-hydroxydopamine-induced neurotoxicity.
Topics: Animals; Animals, Newborn; Antioxidants; Caffeic Acids; Cell Death; Cerebellum; Free Radicals; Immunohistochemistry; In Vitro Techniques; Mesencephalon; Neurons; Neurotoxicity Syndromes; Oxidopamine; Peroxynitrous Acid; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Sympatholytics | 2006 |
The activities of antioxidant enzymes and the level of malondialdehyde in cerebellum of rats subjected to methotrexate: protective effect of caffeic acid phenethyl ester.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Cerebellum; Male; Malondialdehyde; Methotrexate; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2006 |
Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine.
Topics: Acetylcarnitine; Analgesics; Animals; Caffeic Acids; Cells, Cultured; Ganglia, Spinal; Gene Expression Regulation; Mice; Mice, Inbred ICR; Neurons, Afferent; NF-kappa B; Phenylethyl Alcohol; Proto-Oncogene Proteins c-rel; Receptors, Metabotropic Glutamate; RNA, Messenger; Transcription Factor RelA; Transcriptional Activation; Up-Regulation | 2006 |
Enhancement of caffeic acid phenethyl ester on all-trans retinoic acid-induced differentiation in human leukemia HL-60 cells.
Topics: Antineoplastic Agents; Blotting, Western; Caffeic Acids; CCAAT-Enhancer-Binding Proteins; CD11b Antigen; Cell Cycle; Cell Differentiation; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Lipopolysaccharide Receptors; Phenylethyl Alcohol; Receptors, Retinoic Acid; Receptors, TNF-Related Apoptosis-Inducing Ligand; Retinoic Acid Receptor alpha; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin | 2006 |
Protective effects of caffeic acid phenethyl ester on skeletal muscle ischemia-reperfusion injury in rats.
Topics: Adenosine Deaminase; Animals; Caffeic Acids; Creatine Kinase; Male; Muscle, Skeletal; Peroxidase; Phenylethyl Alcohol; Protein Carbonylation; Rats; Rats, Wistar; Reperfusion Injury; Xanthine Oxidase | 2006 |
Role of caffeic acid phenethyl ester, an active component of propolis, against NAOH-induced esophageal burns in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Burns, Chemical; Caffeic Acids; Caustics; Esophageal Stenosis; Esophagus; Hydroxyproline; Lipid Peroxidation; Male; Malondialdehyde; Phenylethyl Alcohol; Propolis; Random Allocation; Rats; Rats, Wistar; Sodium Hydroxide | 2006 |
The interleukin 1beta-induced expression of human prostaglandin F2alpha receptor messenger RNA in human myometrial-derived ULTR cells requires the transcription factor, NFkappaB.
Topics: Caffeic Acids; Cell Line; Cell Nucleus; Female; Humans; Interleukin-1beta; Leupeptins; Myometrium; NF-kappa B; Phenylethyl Alcohol; Proteasome Inhibitors; Receptors, Prostaglandin; Response Elements; RNA, Messenger; Transcription Factor RelA | 2006 |
The effect of caffeic acid phenethyl ester (CAPE) on histopathological changes in testicular ischemia-reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caffeic Acids; Immunohistochemistry; Injections, Intraperitoneal; Male; Nitric Oxide Synthase Type II; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion Injury; Spermatic Cord Torsion; Testis | 2006 |
Changes in membrane cholesterol of pituitary tumor (GH3) cells regulate the activity of large-conductance Ca2+-activated K+ channels.
Topics: Action Potentials; Animals; Apamin; beta-Cyclodextrins; Caffeic Acids; Calcium; Cholesterol; Cilostazol; Dexamethasone; Diazoxide; Glyburide; Indoles; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Membrane Lipids; Phenylethyl Alcohol; Pituitary Neoplasms; Rats; Tetrazoles; Tumor Cells, Cultured | 2006 |
Methotrexate-induced renal oxidative stress in rats: the role of a novel antioxidant caffeic acid phenethyl ester.
Topics: Animals; Caffeic Acids; Catalase; Free Radical Scavengers; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Methotrexate; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2006 |
Caffeic acid phenethyl ester induces growth arrest and apoptosis of colon cancer cells via the beta-catenin/T-cell factor signaling.
Topics: Annexin A5; Apoptosis; beta Catenin; Blotting, Western; Caffeic Acids; Cell Cycle; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Cyclin D1; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Genes, myc; Genes, Reporter; Humans; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection | 2006 |
Inhibitory effect of caffeic acid phenethyl ester on the growth of SW480 colorectal tumor cells involves beta-catenin associated signaling pathway down-regulation.
Topics: Animals; Apoptosis; beta Catenin; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; Humans; Phenylethyl Alcohol; Signal Transduction; Tetrazolium Salts; Thiazoles | 2006 |
Caffeic acid phenethyl ester modifies the Th1/Th2 balance in ileal mucosa after gamma-irradiation in the rat by modulating the cytokine pattern.
Topics: Animals; Apoptosis; Caffeic Acids; Caspase 3; CD4-Positive T-Lymphocytes; Cytokines; Gamma Rays; Ileum; Intestinal Mucosa; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Th1 Cells; Th2 Cells; Time Factors | 2006 |
Caffeic acid phenethyl ester prevents cadmium-induced cardiac impairment in rat.
Topics: Animals; Antioxidants; Cadmium Chloride; Caffeic Acids; Heart Diseases; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar | 2006 |
Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-kappaB in cardiomyocytes.
Topics: Animals; Animals, Newborn; Aorta; Caffeic Acids; Constriction, Pathologic; Heart Failure; Hypertrophy, Left Ventricular; Indoles; Models, Animal; Myocytes, Cardiac; Natriuretic Peptide, Brain; NF-kappa B; Phenylethyl Alcohol; Quinolines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; RNA Interference; RNA, Small Interfering; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Stress, Mechanical; Ventricular Remodeling | 2006 |
Ameliorating role of caffeic acid phenethyl ester (CAPE) against isoniazid-induced oxidative damage in red blood cells.
Topics: Animals; Antioxidants; Antitubercular Agents; Caffeic Acids; Erythrocytes; Isoniazid; Male; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar | 2006 |
Discoidin domain receptor 1 contributes to eosinophil survival in an NF-kappaB-dependent manner in Churg-Strauss syndrome.
Topics: Adult; Aged; Apoptosis; Caffeic Acids; Cell Line; Cell Survival; Churg-Strauss Syndrome; Collagen; Cytokines; Discoidin Domain Receptor 1; Eosinophils; Female; Gene Expression Regulation; Humans; Kidney; Male; Middle Aged; NF-kappa B; Phenylethyl Alcohol; Protein Isoforms; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering | 2007 |
Influence of electromagnetic fields and protective effect of CAPE on bone mineral density in rats.
Topics: Animals; Bone Density; Caffeic Acids; Cell Phone; Electromagnetic Fields; Femur; Male; Phenylethyl Alcohol; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiography; Rats; Rats, Sprague-Dawley; Spine | 2006 |
The effect of caffeic acid phenethyl ester on bacterial translocation and intestinal damage in cholestatic rats.
Topics: Animals; Bacterial Translocation; Caffeic Acids; Cholestasis, Extrahepatic; Enterobacteriaceae; Ileum; Liver; Lymph Nodes; Male; Mesentery; Phenylethyl Alcohol; Rats; Rats, Wistar; Staphylococcus aureus | 2006 |
Caffeic acid phenethyl ester suppresses oxidative stress in Escherichia coli-induced pyelonephritis in rats.
Topics: Animals; Caffeic Acids; Catalase; Escherichia coli; Glutathione Peroxidase; Inflammation; Kidney; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Pyelonephritis; Rats; Rats, Wistar; Superoxide Dismutase; Xanthine Oxidase | 2007 |
Carrageenan induces interleukin-8 production through distinct Bcl10 pathway in normal human colonic epithelial cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; B-Cell CLL-Lymphoma 10 Protein; Caffeic Acids; Carrageenan; Cell Line; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; Humans; I-kappa B Proteins; Interleukin-8; Intestinal Mucosa; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Phosphorylation; Promoter Regions, Genetic; Rats; RNA, Small Interfering; Signal Transduction; Transfection | 2007 |
A single dose of caffeic acid phenethyl ester prevents initiation in a medium-term rat hepatocarcinogenesis model.
Topics: 2-Acetylaminofluorene; Animals; Caffeic Acids; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Cytotoxins; Diethylnitrosamine; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Glutathione S-Transferase pi; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; RNA, Messenger | 2006 |
Combined therapy of teicoplanin and caffeic acid phenethyl ester (CAPE) in the treatment of experimental mediastinitis in the rat.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Mediastinitis; Methicillin Resistance; Osteomyelitis; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin | 2006 |
A preliminary study of the levels of testis oxidative stress parameters after MK-801-induced experimental psychosis model: protective effects of CAPE.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Lipid Peroxidation; Male; Malondialdehyde; Nerve Tissue Proteins; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Paraffin Embedding; Phenylethyl Alcohol; Protein Denaturation; Psychoses, Substance-Induced; Rats; Rats, Wistar; Seminiferous Tubules; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Testis; Thiobarbituric Acid Reactive Substances | 2007 |
Bifunctional alkylating agent-induced p53 and nonclassical nuclear factor kappaB responses and cell death are altered by caffeic acid phenethyl ester: a potential role for antioxidant/electrophilic response-element signaling.
Topics: Alkylating Agents; Antioxidants; Blotting, Western; Caffeic Acids; Cell Death; Electrophoresis, Polyacrylamide Gel; Genes, p53; Genes, Reporter; Humans; Keratinocytes; L-Lactate Dehydrogenase; Luciferases; Mechlorethamine; Mustard Gas; NF-kappa B; Phenylethyl Alcohol; Receptors, Aryl Hydrocarbon; Response Elements; Signal Transduction; Transfection | 2007 |
Attenuation of oxidative stress in plasma and tissues of rats with experimentally induced hyperthyroidism by caffeic acid phenylethyl ester.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Caffeic Acids; Glutathione; Glutathione Disulfide; Hyperthyroidism; Liver; Male; Myocardium; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Thyrotropin; Thyroxine; Triiodothyronine | 2007 |
Antifungal chemical compounds identified using a C. elegans pathogenicity assay.
Topics: Animals; Antifungal Agents; Biofilms; Caenorhabditis elegans; Caffeic Acids; Candida; Enoxacin; Female; Fluconazole; Intestines; Mice; Mice, Inbred BALB C; Naphthoquinones; NF-kappa B; Phenylethyl Alcohol | 2007 |
Stability of caffeic acid phenethyl ester and its fluorinated derivative in rat plasma.
Topics: Animals; Caffeic Acids; Chromatography, High Pressure Liquid; Drug Stability; Fluorine; Hydrogen-Ion Concentration; Phenylethyl Alcohol; Rats; Sodium Fluoride; Temperature | 2007 |
Oxidative stress in prefrontal cortex of rat exposed to MK-801 and protective effects of CAPE.
Topics: Animals; Behavior, Animal; Brain Chemistry; Caffeic Acids; Cytotoxins; Dizocilpine Maleate; Drug Interactions; Male; Neuroprotective Agents; Oxidative Stress; Phenylethyl Alcohol; Prefrontal Cortex; Protein Carbonylation; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2007 |
In vitro and in vivo stability of caffeic acid phenethyl ester, a bioactive compound of propolis.
Topics: Animals; Caffeic Acids; Chlorogenic Acid; Cinnamates; Depsides; Drug Stability; Humans; Hydrolysis; Phenylethyl Alcohol; Propolis; Rats; Rosmarinic Acid | 2007 |
Beneficial effects of caffeic acid phenethyl ester (CAPE) on the ischaemia-reperfusion injury in rat skin flaps.
Topics: Animals; Antioxidants; Caffeic Acids; Drug Evaluation, Preclinical; Female; Glutathione; Glutathione Peroxidase; Injections, Intraperitoneal; Malondialdehyde; Necrosis; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Surgical Flaps | 2007 |
Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Caffeic Acids; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Inflammation Mediators; Ischemic Attack, Transient; Male; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome | 2007 |
Protective effects of caffeic acid phenethyl ester, vitamin C, vitamin E and N-acetylcysteine on vancomycin-induced nephrotoxicity in rats.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Blood Urea Nitrogen; Caffeic Acids; Catalase; Disease Models, Animal; Drinking; Drug Combinations; Injections, Intramuscular; Injections, Intraperitoneal; Kidney; Kidney Diseases; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Vancomycin; Vitamin E; Water Supply | 2007 |
Drastic effect of several caffeic acid derivatives on the induction of heme oxygenase-1 expression revealed by quantitative real-time RT-PCR.
Topics: Animals; Caffeic Acids; Cell Line; Cell Line, Tumor; Enzyme Induction; Heme Oxygenase-1; Humans; Mice; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
The effect of caffeic acid phenethyl ester on the prevention of experimentally induced myringosclerosis.
Topics: Animals; Caffeic Acids; Male; NF-kappa B; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Sprague-Dawley; Sclerosis; Tympanic Membrane | 2007 |
Characterization of a novel and potent collagen antagonist, caffeic acid phenethyl ester, in human platelets: in vitro and in vivo studies.
Topics: Animals; Biological Assay; Blood Platelets; Caffeic Acids; Collagen; Crotalid Venoms; Depression, Chemical; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Hydroxyl Radical; Immunoblotting; Integrin alpha2beta1; Lectins, C-Type; Mesenteric Arteries; Mice; Phenylethyl Alcohol; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Spectrometry, Fluorescence; Thrombosis; Thromboxane B2; Viper Venoms | 2007 |
Effect of caffeic acid phenethyl ester on the regression of endometrial explants in an experimental rat model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caffeic Acids; Catalase; Cyclooxygenase 2; Disease Models, Animal; Endometriosis; Endometrium; Female; Lipid Peroxidation; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Wistar; Statistics, Nonparametric; Superoxide Dismutase; Transplantation, Autologous; Uterus | 2007 |
The neuroprotective effects of caffeic acid phenethyl ester (CAPE) in the hippocampal formation of cigarette smoke exposed rabbits.
Topics: Animals; Apoptosis; Caffeic Acids; DNA Damage; Hippocampus; Injections, Intraperitoneal; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Nicotiana; Phenylethyl Alcohol; Rabbits; Reactive Oxygen Species; Smoke; Superoxide Dismutase | 2007 |
CAPE (caffeic acid phenethyl ester) stimulates glucose uptake through AMPK (AMP-activated protein kinase) activation in skeletal muscle cells.
Topics: AMP-Activated Protein Kinases; Animals; Biological Transport; Caffeic Acids; Cell Differentiation; Cell Line; Enzyme Activation; Glucose; Multienzyme Complexes; Muscle Fibers, Skeletal; Myoblasts; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats | 2007 |
N-acetyl cysteine and caffeic acid phenethyl ester sensitize astrocytoma cells to Fas-mediated cell death in a redox-dependent manner.
Topics: Acetylcysteine; Astrocytoma; Caffeic Acids; Caspase Inhibitors; Caspases; Cell Death; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Humans; Membrane Potentials; Mitochondrial Membranes; Models, Biological; Oxidation-Reduction; Phenylethyl Alcohol; Reactive Oxygen Species; Time Factors | 2007 |
Effects of caffeic acid phenethyl ester on the histopathological changes in the lungs of cigarette smoke-exposed rabbits.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Inflammation; Lung; Male; Nicotiana; Phenylethyl Alcohol; Rabbits; Smoke | 2007 |
Regulation of monocarboxylate transporter 1 (MCT1) promoter by butyrate in human intestinal epithelial cells: involvement of NF-kappaB pathway.
Topics: Butyrates; Caco-2 Cells; Caffeic Acids; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Humans; Intestinal Mucosa; Monocarboxylic Acid Transporters; NF-kappa B; Phenylethyl Alcohol; Protein Kinase C; Response Elements; Signal Transduction; Substrate Specificity; Symporters | 2008 |
Protein phosphatase 2A (PP2A) has a potential role in CAPE-induced apoptosis of CCRF-CEM cells via effecting human telomerase reverse transcriptase activity.
Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Phenylethyl Alcohol; Protein Phosphatase 2; Telomerase | 2007 |
Antiplatelet activity of caffeic acid phenethyl ester is mediated through a cyclic GMP-dependent pathway in human platelets.
Topics: Blood Platelets; Caffeic Acids; Cell Adhesion Molecules; Cyclic AMP; Cyclic GMP; Humans; Microfilament Proteins; Phenylethyl Alcohol; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Thromboembolism | 2007 |
Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Caffeic Acids; Disease Models, Animal; Female; Histamine Release; Immunoglobulin E; Mice; Mice, Inbred ICR; NF-kappa B; Ovalbumin; Phenylethyl Alcohol; Tumor Necrosis Factor-alpha | 2008 |
Cytotoxicity of NF-kappaB inhibitors Bay 11-7085 and caffeic acid phenethyl ester to Ramos and other human B-lymphoma cell lines.
Topics: Active Transport, Cell Nucleus; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytoplasm; Cytotoxins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lymphoma, B-Cell; Membrane Potential, Mitochondrial; Necrosis; Nitriles; Phenylethyl Alcohol; Protein Binding; Sulfones; Time Factors; Transcription Factor RelA | 2007 |
Antibacterial and free-radical scavenging activities of Sonoran propolis.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Bees; Butylated Hydroxytoluene; Caffeic Acids; Flavones; Flavonols; Food Microbiology; Free Radical Scavengers; Gram-Positive Bacteria; Mexico; Microbial Sensitivity Tests; Phenols; Phenylethyl Alcohol; Propolis; Rutin; Staphylococcus aureus; Vitamins | 2007 |
Caffeic acid phenethyl ester accelerates cutaneous wound healing in a rat model and decreases oxidative stress.
Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Glutathione; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Reactive Oxygen Species; Skin; Superoxide Dismutase; Wound Healing | 2007 |
The effects of caffeic acid phenethyl ester (CAPE) on TNBS-induced colitis in ovariectomized rats.
Topics: Animals; Caffeic Acids; Catalase; Colitis; Female; Glutathione; Malondialdehyde; Ovary; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Statistics, Nonparametric; Trinitrobenzenesulfonic Acid | 2008 |
N-acetylcysteine stimulates osteoblastic differentiation of mouse calvarial cells.
Topics: Acetylcysteine; Alkaline Phosphatase; Animals; Antioxidants; Bacterial Proteins; Bacterial Toxins; Bone Morphogenetic Proteins; Caffeic Acids; Cell Differentiation; Cells, Cultured; Glutathione; Mice; Osteoblasts; Osteogenesis; Phenylethyl Alcohol; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Skull | 2008 |
Effects of caffeic acid phenethyl ester on pancreatitis in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Bacterial Translocation; Bronchoalveolar Lavage Fluid; Caffeic Acids; Detergents; Disease Models, Animal; Glycodeoxycholic Acid; L-Lactate Dehydrogenase; Lung; Male; Malondialdehyde; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2008 |
Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kappa B signaling in urothelial cancer cells.
Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Chromones; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Morpholines; Neoplasm Proteins; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Survivin; Transfection; Urinary Bladder Neoplasms | 2007 |
Caffeic acid phenethyl ester induces mitochondria-mediated apoptosis in human myeloid leukemia U937 cells.
Topics: Apoptosis; Caffeic Acids; Caspase 3; Cell Line, Tumor; Chromatin; Cytochromes c; DNA Fragmentation; Endoplasmic Reticulum; Eukaryotic Initiation Factor-2; fas Receptor; Humans; Leukemia, Myeloid; Mitochondria; Phenylethyl Alcohol; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Receptors, Death Domain; Transcription Factor CHOP; U937 Cells | 2008 |
Caffeic acid phenethyl ester reduces mortality and sepsis-induced lung injury in rats.
Topics: Animals; Apoptosis; Caffeic Acids; Cytokines; Female; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Sepsis; Survival Analysis | 2007 |
Differential regulation of c-Jun N-terminal kinase and NF-kappaB pathway by caffeic acid phenethyl ester in astroglial and monocytic cells.
Topics: Astrocytes; Caffeic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fetus; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; JNK Mitogen-Activated Protein Kinases; Models, Biological; Monocytes; NF-kappa B; Phenylethyl Alcohol; Signal Transduction; Tumor Necrosis Factor-alpha | 2008 |
Caffeic acid phenethyl ester and its related compounds limit the functional alterations of the isolated mouse brain and liver mitochondria submitted to in vitro anoxia-reoxygenation: relationship to their antioxidant activities.
Topics: Anaerobiosis; Animals; Anisotropy; Antioxidants; Brain; Caffeic Acids; Coumaric Acids; Cytochromes c; Dose-Response Relationship, Drug; Male; Mice; Mitochondria; Mitochondria, Liver; Mitochondrial Membranes; Molecular Structure; Oxygen; Phenylethyl Alcohol; Thiobarbituric Acid Reactive Substances | 2008 |
DNA damage induced by caffeic acid phenyl ester in the presence of Cu(II) ions: potential mechanism of its anticancer properties.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Catalase; Cattle; Copper; DNA; DNA Damage; Edetic Acid; Electrophoresis, Agar Gel; Free Radical Scavengers; Phenylethyl Alcohol; Reactive Oxygen Species; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2008 |
Caffeic acid phenethyl ester (CAPE) protects brain against oxidative stress and inflammation induced by diabetes in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Caffeic Acids; Cytokines; Cytoprotection; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Encephalitis; Gene Expression Regulation; Lipid Peroxidation; Male; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Streptozocin | 2008 |
Caffeic acid phenethyl ester attenuates allergic airway inflammation and hyperresponsiveness in murine model of ovalbumin-induced asthma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Caffeic Acids; Cell Count; Cytokines; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Peroxides; Phenylethyl Alcohol; Respiratory Hypersensitivity | 2008 |
Caffeic acid phenethyl ester protects rabbit brains against permanent focal ischemia by antioxidant action: a biochemical and planimetric study.
Topics: Animals; Antioxidants; Biomarkers; Brain Infarction; Brain Ischemia; Brain Mapping; Caffeic Acids; Catalase; Enzyme Inhibitors; Glutathione; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rabbits; Spectrophotometry; Treatment Outcome; Xanthine Oxidase | 2008 |
Leishmania major infection activates NF-kappaB and interferon regulatory factors 1 and 8 in human dendritic cells.
Topics: Animals; Binding Sites; Caffeic Acids; Cells, Cultured; Dendritic Cells; DNA; Gene Expression Profiling; Humans; Immunologic Factors; Interferon Regulatory Factor-1; Interferon Regulatory Factors; Interleukin-12; Leishmania major; NF-kappa B; Phenylethyl Alcohol; Promoter Regions, Genetic; Protein Binding; Up-Regulation | 2008 |
Quantitative determination of fluorinated caffeic acid phenethyl ester derivative from rat blood plasma by liquid chromatography-electrospray ionization tandem mass spectrometry.
Topics: Animals; Caffeic Acids; Chromatography, Liquid; Fluorine; Male; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Evidence that the anticarcinogenic effect of caffeic acid phenethyl ester in the resistant hepatocyte model involves modifications of cytochrome P450.
Topics: 2-Acetylaminofluorene; Animals; Anticarcinogenic Agents; Caffeic Acids; Cytochrome P-450 Enzyme System; Diethylnitrosamine; gamma-Glutamyltransferase; Hepatocytes; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Phenylethyl Alcohol; Rats; Rats, Inbred F344 | 2008 |
Potential cytoprotection: antioxidant defence by caffeic acid phenethyl ester against free radical-induced damage of lipids, DNA, and proteins.
Topics: Adult; Amidines; Antioxidants; Caffeic Acids; Comet Assay; Cytoprotection; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Erythrocyte Membrane; Humans; Hydrogen Peroxide; Lipid Peroxidation; Male; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Protein Carbonylation; Reactive Oxygen Species; Structure-Activity Relationship; Time Factors | 2008 |
Protective effect of caffeic acid phenethyl ester against carbon tetrachloride-induced hepatotoxicity in mice.
Topics: Animals; Caffeic Acids; Carbon Tetrachloride; Caspase 3; Caspase 8; Catalase; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Fas Ligand Protein; fas Receptor; Glutathione Transferase; Liver Diseases; Male; Mice; Mice, Inbred ICR; Phenylethyl Alcohol; Protective Agents; Solvents; Superoxide Dismutase | 2008 |
Caffeic acid phenethyl ester preferentially enhanced radiosensitizing and increased oxidative stress in medulloblastoma cell line.
Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Glutathione; Humans; In Situ Nick-End Labeling; Medulloblastoma; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Radiation-Sensitizing Agents; Reactive Oxygen Species | 2008 |
Protective effect of caffeic acid phenethyl ester on tert-butyl hydroperoxide-induced oxidative hepatotoxicity and DNA damage.
Topics: Animals; Anticarcinogenic Agents; Caffeic Acids; Cell Line, Tumor; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Lipid Peroxidation; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; tert-Butylhydroperoxide | 2008 |
Effects of propolis and CAPE on proliferation and apoptosis of McCoy-Plovdiv cell line.
Topics: Apoptosis; Caffeic Acids; Cell Line; Cell Proliferation; Comet Assay; DNA Damage; Fibroblasts; Humans; Immunohistochemistry; Phenylethyl Alcohol; Proliferating Cell Nuclear Antigen; Propolis; Synovial Membrane; Tumor Suppressor Protein p53 | 2008 |
Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-kappaB pathways.
Topics: Animals; Caffeic Acids; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Shock, Septic; Signal Transduction; Tumor Necrosis Factor-alpha | 2008 |
Cytoprotection of human endothelial cells from menadione cytotoxicity by caffeic acid phenethyl ester: the role of heme oxygenase-1.
Topics: Antioxidants; Blotting, Western; Caffeic Acids; Carbon Monoxide; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Heme Oxygenase-1; Humans; Oxidative Stress; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; Umbilical Veins; Up-Regulation; Vitamin K 3 | 2008 |
New anti-inflammatory 4-methylated steroids from the Formosan soft coral Nephthea chabroli.
Topics: Animals; Anthozoa; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Cell Line; Cyclooxygenase 2; Enzyme Inhibitors; Lipopolysaccharides; Macrophage Activation; Macrophages; Methylation; Mice; Molecular Conformation; Molecular Structure; Nitric Oxide Synthase Type II; Nuclear Magnetic Resonance, Biomolecular; Phenylethyl Alcohol; Reference Standards; Spectrophotometry, Infrared; Steroids; Up-Regulation | 2008 |
Effects of caffeic acid phenethyl ester (CAPE) on sepsis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bronchoalveolar Lavage Fluid; Caffeic Acids; Inflammation Mediators; Infusions, Parenteral; Kidney; L-Lactate Dehydrogenase; Liver; Lung; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Sepsis | 2008 |
Inhibitory effect of caffeic acid phenethyl ester (CAPE) on LPS-induced inflammation of human middle ear epithelial cells.
Topics: Caffeic Acids; Cell Line; Gene Expression; Humans; Inflammation Mediators; Interleukin-8; Lipopolysaccharides; NF-kappa B; Otitis Media; Phenylethyl Alcohol; Tumor Necrosis Factor-alpha | 2008 |
The protective effect of CAPE on hepatic ischemia/reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Caffeic Acids; Glutathione; Lipid Peroxidation; Liver; Male; Neutrophils; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury | 2008 |
Caffeic acid phenethyl ester prevents cerebellar granule neurons (CGNs) against glutamate-induced neurotoxicity.
Topics: Animals; Animals, Newborn; Caffeic Acids; Caspase 3; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Membrane Potentials; Mitochondria; Neurons; Neuroprotective Agents; Neurotoxins; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Phenylethyl Alcohol; Phosphorylation; Rats | 2008 |
Protective effects of caffeic acid phenethyl ester on intestinal ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Glutathione; Glutathione Peroxidase; Intestinal Diseases; Intestinal Mucosa; Jejunum; Lipid Peroxidation; Male; Malondialdehyde; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2009 |
CAPE (caffeic acid phenethyl ester)-based propolis extract (Bio 30) suppresses the growth of human neurofibromatosis (NF) tumor xenografts in mice.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Female; Humans; Mice; Mice, Nude; Neurofibromatosis 1; Neurofibromatosis 2; p21-Activated Kinases; Phenylethyl Alcohol; Propolis; Xenograft Model Antitumor Assays | 2009 |
Effect of NFkappaB inhibition by CAPE on skeletal muscle ischemia-reperfusion injury.
Topics: Animals; Caffeic Acids; Male; Medicine, Traditional; Muscle, Skeletal; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury | 2009 |
Caffeic acid phenethyl ester induces apoptosis of human pancreatic cancer cells involving caspase and mitochondrial dysfunction.
Topics: Antioxidants; Apoptosis; Caffeic Acids; Caspases; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Membrane Potential, Mitochondrial; Mitochondria; Pancreatic Neoplasms; Phenylethyl Alcohol; Substrate Specificity; Time Factors | 2008 |
Caffeic acid phenethyl ester modulates methotrexate-induced oxidative stress in testes of rat.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Caffeic Acids; Cytotoxins; Drug Antagonism; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Methotrexate; Organ Size; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase; Testis | 2008 |
Zinc deficiency induces vascular pro-inflammatory parameters associated with NF-kappaB and PPAR signaling.
Topics: Animals; Atherosclerosis; Caffeic Acids; Cell Adhesion; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation; Inflammation; Male; Mice; Monocytes; NF-kappa B; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Phenylethyl Alcohol; Receptors, LDL; Rosiglitazone; Thiazolidinediones; Zinc | 2008 |
Protective effects of caffeic acid phenethyl ester on radiation induced lung injury in rats.
Topics: Animals; Antioxidants; Caffeic Acids; Gamma Rays; Lung; Lung Injury; Male; Malondialdehyde; Phenylethyl Alcohol; Radiation Injuries, Experimental; Rats; Superoxide Dismutase | 2008 |
Artepillin C (ARC) in Brazilian green propolis selectively blocks oncogenic PAK1 signaling and suppresses the growth of NF tumors in mice.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Female; Mice; Mice, Nude; Neoplasms, Experimental; Neurofibromatoses; p21-Activated Kinases; Phenylethyl Alcohol; Phenylpropionates; Propolis; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays | 2009 |
The effects of hydroxycinnamic acid derivatives on adiponectin secretion.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Caffeic Acids; Coumaric Acids; Curcumin; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Phenylpropionates; Phytotherapy; Pioglitazone; Plant Extracts; Plant Oils; Rice Bran Oil; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2009 |
Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats.
Topics: Adenosine Deaminase; Administration, Oral; Animals; Antioxidants; Antitubercular Agents; Caffeic Acids; Disease Models, Animal; Drinking; Drug Therapy, Combination; Erythrocytes; Injections, Intraperitoneal; Isoniazid; Male; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Xanthine Oxidase | 2008 |
Inhibition of human catechol-O-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee.
Topics: Adult; Biocatalysis; Caffeic Acids; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Chlorogenic Acid; Coffee; Computational Biology; Cytosol; Estrogens, Catechol; Female; Flavonoids; Humans; Inhibitory Concentration 50; Kinetics; Liver; Methylation; Models, Molecular; Phenols; Phenylethyl Alcohol; Placenta; Polyphenols; Protein Binding; Protein Structure, Secondary | 2009 |
Decreasing the expression of LFA-1 and ICAM-1 as the major mechanism for the protective effect of caffeic acid phenethyl ester on ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Caffeic Acids; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Phenylethyl Alcohol; Reperfusion Injury; Surgical Flaps | 2009 |
Taurocholate feeding to bile duct ligated rats prevents caffeic acid-induced bile duct damage by changes in cholangiocyte VEGF expression.
Topics: Animals; Apoptosis; Bile; Bile Ducts; Caffeic Acids; Cell Proliferation; Cholagogues and Choleretics; Cytotoxins; Immunohistochemistry; Ligation; Male; Phenylethyl Alcohol; Rats; Rats, Inbred F344; Receptors, Vascular Endothelial Growth Factor; Taurocholic Acid; Vascular Endothelial Growth Factors | 2009 |
Caffeic acid phenethyl ester (CAPE) ameliorates cisplatin-induced hepatotoxicity in rabbit.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeic Acids; Cisplatin; Glutathione; Liver; Male; Malondialdehyde; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Phenylethyl Alcohol; Rabbits; Xanthine Oxidase | 2010 |
Caffeic acid phenethyl ester inhibits osteoclastogenesis by suppressing NF kappaB and downregulating NFATc1 and c-Fos.
Topics: Animals; Bone Marrow; Caffeic Acids; Cell Differentiation; Cells, Cultured; Female; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Phenylethyl Alcohol; Proto-Oncogene Proteins c-fos; RANK Ligand | 2009 |
Caffeic acid phenethyl ester accumulates beta-catenin through GSK-3beta and participates in proliferation through mTOR in C2C12 cells.
Topics: Actins; Animals; beta Catenin; Blotting, Western; Caffeic Acids; Cell Line; Cell Proliferation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indicators and Reagents; Mice; Myoblasts; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Protein Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases | 2009 |
Novel approach for the prevention of contrast nephropathy.
Topics: Acetylcysteine; Animals; Caffeic Acids; Catalase; Contrast Media; Creatinine; Glutathione Peroxidase; Kidney; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Superoxide Dismutase | 2010 |
Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF-kappaB and induction of apoptosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biomarkers, Tumor; Caffeic Acids; Cell Cycle; Cholangiocarcinoma; Cytotoxins; Dimethyl Sulfoxide; DNA; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Liver; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Organ Size; Phenylethyl Alcohol; Proliferating Cell Nuclear Antigen; Signal Transduction; Transcription Factor RelA; Transplantation, Heterologous; Up-Regulation | 2009 |
Inhibition of store-operated Ca2+ entry channels and K+ channels by caffeic acid phenethylester in T lymphocytes.
Topics: Caffeic Acids; Calcium; Calcium Signaling; CD28 Antigens; CD3 Complex; Cell Line; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electrophysiology; Humans; Inositol 1,4,5-Trisphosphate; Interleukin-2; Ionomycin; Jurkat Cells; Kidney; Patch-Clamp Techniques; Phenylethyl Alcohol; Phytohemagglutinins; Potassium Channels, Voltage-Gated; T-Lymphocytes; Thapsigargin; Time Factors | 2009 |
The use of FTIR microscopy for the evaluation of anti-bacterial agents activity.
Topics: Ampicillin; Anti-Bacterial Agents; Caffeic Acids; Gram-Negative Bacteria; Gram-Positive Bacteria; Phenylethyl Alcohol; Spectroscopy, Fourier Transform Infrared | 2009 |
Caffeic acid phenethyl ester protects against tamoxifen-induced hepatotoxicity in rats.
Topics: Animals; Antineoplastic Agents, Hormonal; Antioxidants; Caffeic Acids; Chemical and Drug Induced Liver Injury; Female; Glutathione; Lipid Peroxidation; Liver; Liver Function Tests; Neutrophils; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tamoxifen; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2009 |
Caffeic acid phenethyl ester prevents ovary ischemia/reperfusion injury in rabbits.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Female; Glutathione; Lipid Peroxidation; Ovarian Diseases; Phenylethyl Alcohol; Rabbits; Reperfusion Injury; Thiobarbituric Acid Reactive Substances | 2009 |
A short critique aimed to be constructive to authors, referees, and editors.
Topics: Animals; Antioxidants; Caffeic Acids; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Phenylethyl Alcohol; Reperfusion Injury; Surgical Flaps | 2010 |
The effect of caffeic acid phenethyl ester (CAPE) against cholestatic liver injury in rats.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Caffeic Acids; Cholestasis; Cholestasis, Intrahepatic; gamma-Glutamyltransferase; Glutathione Transferase; Jaundice; Male; Malondialdehyde; Peroxidase; Phenylethyl Alcohol; Rats | 2010 |
Pharmacokinetics of caffeic acid phenethyl ester and its catechol-ring fluorinated derivative following intravenous administration to rats.
Topics: Animals; Area Under Curve; Caffeic Acids; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Half-Life; Injections, Intravenous; Male; Nonlinear Dynamics; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2009 |
Caffeic acid phenethyl ester decreases the level of S-100B protein after middle cerebral artery [correction for after] occlusion in rabbits.
Topics: Animals; Biomarkers; Brain Damage, Chronic; Caffeic Acids; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Male; Nerve Growth Factors; Neuroprotective Agents; Phenylethyl Alcohol; Rabbits; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2009 |
The effect of caffeic acid phenethyl ester on the functions of human monocyte-derived dendritic cells.
Topics: Allergens; Animals; Caffeic Acids; Chemokine CXCL10; Dendritic Cells; Humans; Hypersensitivity; I-kappa B Kinase; Interleukin-10; Interleukin-12; Interleukin-12 Subunit p40; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Propolis; Pyroglyphidae; Signal Transduction; T-Lymphocytes | 2009 |
Anti-inflammatory effects of caffeic acid phenethyl ester (CAPE), a nuclear factor-kappaB inhibitor, on Helicobacter pylori-induced gastritis in Mongolian gerbils.
Topics: Animals; Blotting, Western; Caffeic Acids; Cytotoxins; Gastric Mucosa; Gastritis; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Immunoenzyme Techniques; Interferon-gamma; Interleukin-6; Interleukin-8; Male; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2009 |
Influence of electromagnetic fields on bone fracture in rats: role of CAPE.
Topics: Animals; Biomechanical Phenomena; Bone Density; Caffeic Acids; Electromagnetic Fields; Femur; Fractures, Bone; Male; Phenylethyl Alcohol; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley | 2009 |
Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.
Topics: Caffeic Acids; Drug Design; HIV Integrase; HIV Integrase Inhibitors; Humans; Nitrogen; Phenylethyl Alcohol; Structure-Activity Relationship | 2009 |
Caffeic acid phenethyl ester, a component of beehive propolis, is a novel selective estrogen receptor modulator.
Topics: Animals; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor alpha; Female; Humans; Phenylethyl Alcohol; Propolis; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Uterus | 2010 |
Caffeic acid phenethyl ester, an active component of honeybee propolis attenuates osteoclastogenesis and bone resorption via the suppression of RANKL-induced NF-kappaB and NFAT activity.
Topics: Acid Phosphatase; Active Transport, Cell Nucleus; Animals; Apoptosis; Bone Resorption; Caffeic Acids; Caspase 3; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Humans; I-kappa B Proteins; Isoenzymes; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; NFATC Transcription Factors; Osteoclasts; Phenylethyl Alcohol; Propolis; RANK Ligand; Tartrate-Resistant Acid Phosphatase; Transcription Factor RelA; Tumor Cells, Cultured | 2009 |
Caffeic acid phenethyl ester (CAPE) exhibits significant potential as an antidiabetic and liver-protective agent in streptozotocin-induced diabetic rats.
Topics: Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Glucose; Hypoglycemic Agents; Liver; Male; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Streptozocin | 2009 |
Caffeic acid phenethyl ester, an antioxidant from propolis, protects peripheral blood mononuclear cells of competitive cyclists against hyperthermal stress.
Topics: Antioxidants; Bicycling; Caffeic Acids; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Exercise Test; Glutathione; Hot Temperature; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Male; Necrosis; Phenylethyl Alcohol; Physical Fitness; Propolis; Stress, Physiological; Superoxides | 2009 |
Caffeic acid phenethyl ester is a potent inhibitor of HIF prolyl hydroxylase: structural analysis and pharmacological implication.
Topics: Animals; Caffeic Acids; Cells, Cultured; Enzyme Inhibitors; HEK293 Cells; Heme Oxygenase-1; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Phenylethyl Alcohol; Procollagen-Proline Dioxygenase; Reperfusion Injury; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2010 |
The ultrastructural and biochemical evidences of the beneficial effects of chronic caffeic acid phenethyl ester and melatonin administration on brain and cerebellum of aged rats.
Topics: Aging; Animals; Brain; Caffeic Acids; Cerebellum; Cerebrum; Drug Administration Schedule; Male; Melatonin; Neurons; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2010 |
Efficacy of caffeic acid phenethyl ester (CAPE) in skin B16-F0 melanoma tumor bearing C57BL/6 mice.
Topics: Animals; Caffeic Acids; Cell Cycle; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glutathione; Hydrogen-Ion Concentration; Intracellular Space; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Oxidation-Reduction; Oxygen; Phenylethyl Alcohol; Reactive Oxygen Species; Skin Neoplasms; Spectrophotometry, Ultraviolet; Treatment Outcome | 2011 |
Therapeutic effect of caffeic acid phenethyl ester on cerulein-induced acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Caffeic Acids; Ceruletide; Cytotoxins; Disease Models, Animal; Edema; Leukocyte Count; Lipase; Male; Pancreas; Pancreatitis; Phenylethyl Alcohol; Rats; Rats, Wistar; Treatment Outcome; Tumor Necrosis Factor-alpha | 2009 |
Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells.
Topics: Angiogenesis Inhibitors; Animals; Apitherapy; Bees; Caffeic Acids; Cell Line; Cell Movement; Cell Proliferation; Endothelial Cells; Fatty Acids; Fibroblasts; Humans; Phenylethyl Alcohol; Pollen; Propolis; Umbilical Veins; Vascular Endothelial Growth Factor A | 2009 |
Protective effect of caffeic acid phenethyl ester on cyclosporine A-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Caffeic Acids; Cyclosporine; Disease Models, Animal; Female; Immunosuppressive Agents; Kidney; Kidney Diseases; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar | 2009 |
Anticlastogenic effect of caffeic acid phenethyl ester on cisplatin-induced chromosome aberrations in rat bone marrow cells.
Topics: Animals; Antimutagenic Agents; Antineoplastic Agents; Antioxidants; Bone Marrow Cells; Caffeic Acids; Chromosome Aberrations; Cisplatin; Dose-Response Relationship, Drug; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley | 2010 |
Caffeic acid phenethyl ester inhibits arterial smooth muscle cell proliferation and migration in vitro and in vivo using a local delivery system.
Topics: Animals; Blotting, Western; Caffeic Acids; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Vessels; Drug Delivery Systems; Flow Cytometry; Humans; Male; Models, Animal; Muscle, Smooth, Vascular; Phenylethyl Alcohol; Rabbits; Structure-Activity Relationship; Tunica Intima | 2009 |
Optimized enzymatic synthesis of caffeic acid phenethyl ester by RSM.
Topics: Animals; Biocatalysis; Caffeic Acids; Enzymes, Immobilized; Fungal Proteins; Humans; Lipase; Phenylethyl Alcohol | 2010 |
Caffeic acid phenethyl ester inhibits nuclear factor-kappaB and protein kinase B signalling pathways and induces caspase-3 expression in primary human CD4+ T cells.
Topics: Antigens, Dermatophagoides; Asthma; Caffeic Acids; Caspase 3; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Humans; Lymphocyte Activation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Phosphorylation; Propolis; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Receptors, CCR4; Receptors, CXCR3; Signal Transduction; T-Lymphocyte Subsets | 2010 |
Effect of caffeic acid phenethyl ester on the hemostatic alterations associated with toxic-induced acute liver failure.
Topics: Animals; Blood Coagulation Tests; Body Weight; Caffeic Acids; Catalase; Glutathione; Hemostasis; Liver Failure, Acute; Liver Function Tests; Male; Oxidative Stress; Phenylethyl Alcohol; Platelet Count; Rats; Rats, Wistar; Superoxide Dismutase | 2010 |
Constitutive and tumor necrosis factor-alpha-stimulated activation of nuclear factor-kappaB in immortalized endometriotic cells and their suppression by trichostatin A.
Topics: Caffeic Acids; Cell Division; Cell Line, Transformed; Endometriosis; Endometrium; Female; Histone Deacetylase Inhibitors; Humans; Hydrogen Peroxide; Hydroxamic Acids; I-kappa B Kinase; MAP Kinase Kinase Kinases; Oxidants; Phenylethyl Alcohol; Phosphorylation; Stromal Cells; TNF Receptor-Associated Factor 2; TNF Receptor-Associated Factor 6; Transcription Factor RelA | 2010 |
Ameliorative effect of caffeic acid phenethyl ester on histopathological and biochemical changes induced by cigarette smoke in rat kidney.
Topics: Animals; Antioxidants; Blood Chemical Analysis; Caffeic Acids; Dose-Response Relationship, Drug; Inhalation Exposure; Kidney; Kidney Diseases; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Tobacco Smoke Pollution | 2010 |
Caffeic acid phenethyl ester triggers apoptosis through induction of loss of mitochondrial membrane potential in CCRF-CEM cells.
Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Death; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Membrane Potential, Mitochondrial; Phenylethyl Alcohol; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2011 |
Structure-activity relationships in the cytoprotective effect of caffeic acid phenethyl ester (CAPE) and fluorinated derivatives: effects on heme oxygenase-1 induction and antioxidant activities.
Topics: Antioxidants; Caffeic Acids; Cell Line; Cytoprotection; Enzyme Induction; Gene Expression Regulation; Halogenation; Heme Oxygenase-1; Humans; Intracellular Space; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species; RNA, Messenger; Structure-Activity Relationship; Transcription, Genetic; Vitamin K 3 | 2010 |
Protective effects of caffeic acid phenethyl ester on iron-induced liver damage in rats.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Caffeic Acids; Catalase; Dextrans; Female; Glutathione Peroxidase; Iron; Lipid Peroxidation; Liver; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Superoxide Dismutase | 2009 |
Caffeic acid phenethyl ester suppresses the induction of eotaxin in human lung fibroblast cells.
Topics: Caffeic Acids; Cells, Cultured; Chemokine CCL11; Dose-Response Relationship, Drug; Fibroblasts; Humans; Interleukin-13; Lung; NF-kappa B; Phenylethyl Alcohol; Tumor Necrosis Factor-alpha | 2010 |
Inhibitory effect of caffeic acid phenethyl ester on mice bearing tumor involving angiostatic and apoptotic activities.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caffeic Acids; Carcinoma, Ehrlich Tumor; DNA Fragmentation; Endostatins; Female; Humans; Matrix Metalloproteinase 9; Mice; Neovascularization, Pathologic; Phenylethyl Alcohol | 2010 |
Inhibitory effect of caffeic acid phenethyl ester, a plant-derived polyphenolic compound, on rat intestinal contractility.
Topics: Animals; Caffeic Acids; Flavonoids; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Phenols; Phenylethyl Alcohol; Plants; Polyphenols; Potassium Chloride; Rats; Rats, Wistar | 2010 |
Enzymatic synthesis of caffeic acid phenethyl ester analogues in ionic liquid.
Topics: Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Equipment Reuse; Esterification; Fungal Proteins; Humans; Imidazoles; Ionic Liquids; Lipase; Methanol; Phenylethyl Alcohol; Pressure; Sulfonamides | 2010 |
Beneficial effect of caffeic acid phenethyl ester (CAPE) on hepatocyte damage induced by bile duct ligation: an electron microscopic examination.
Topics: Animals; Antioxidants; Bile Ducts; Caffeic Acids; Cholestasis; Hepatocytes; Ligation; Liver; Liver Diseases; Male; Microscopy, Electron, Transmission; Phenylethyl Alcohol; Rats | 2010 |
Chitinase induce the release of IL-8 in human airway epithelial cells, via Ca2+-dependent PKC and ERK pathways.
Topics: Blotting, Western; Butadienes; Caffeic Acids; Carbazoles; Cell Line, Tumor; Chitinases; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Indoles; Interleukin-8; Naphthalenes; NF-kappa B; Nitriles; Phenylethyl Alcohol; Protein Kinase C; Protein Kinase Inhibitors; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2010 |
Synthesis of a series of caffeic acid phenethyl amide (CAPA) fluorinated derivatives: comparison of cytoprotective effects to caffeic acid phenethyl ester (CAPE).
Topics: Caffeic Acids; Cell Line; Cytoprotection; Halogenation; Humans; Hydrogen Peroxide; Oxidative Stress; Phenethylamines; Phenylethyl Alcohol; Umbilical Veins | 2010 |
Caffeic acid phenethyl ester-mediated Nrf2 activation and IkappaB kinase inhibition are involved in NFkappaB inhibitory effect: structural analysis for NFkappaB inhibition.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Cell Culture Techniques; Cell Line, Tumor; Cell Nucleus; Cytosol; Genes, Reporter; Humans; I-kappa B Kinase; Immunoblotting; Lipopolysaccharides; Luciferases; Macrophages; Mice; Molecular Structure; NF-E2-Related Factor 2; NF-kappa B; Phenylethyl Alcohol; Plasmids; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Transfection; Tumor Necrosis Factor-alpha | 2010 |
Biochemical mechanism of caffeic acid phenylethyl ester (CAPE) selective toxicity towards melanoma cell lines.
Topics: Animals; Apoptosis; Ascorbic Acid; Caffeic Acids; Cell Line, Tumor; Glutathione; Male; Melanoma, Experimental; Monophenol Monooxygenase; NAD; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet | 2010 |
Effects of caffeic acid phenethyl ester on isoproterenol-induced myocardial infarction in rats.
Topics: Adrenergic beta-Antagonists; Animals; Aspartate Aminotransferases; Caffeic Acids; Cardiotonic Agents; Creatine Kinase; Cytotoxins; Female; Flavonoids; Humans; Isoproterenol; L-Lactate Dehydrogenase; Myocardial Infarction; Peroxidase; Phenylethyl Alcohol; Randomized Controlled Trials as Topic; Rats; Rats, Wistar; Superoxide Dismutase | 2010 |
Effects of caffeic acid phenethyl ester on thioacetamide-induced hepatic encephalopathy in rats.
Topics: Animals; Antioxidants; Brain; Caffeic Acids; Hepatic Encephalopathy; Male; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Wistar; Thioacetamide | 2010 |
Optimization of ultrasound-accelerated synthesis of enzymatic caffeic acid phenethyl ester by response surface methodology.
Topics: Biocatalysis; Caffeic Acids; Candida; Enzymes, Immobilized; Fungal Proteins; Lipase; Phenylethyl Alcohol; Surface Properties; Ultrasonics | 2011 |
Caffeic acid phenethyl ester inhibits differentiation to adipocytes in 3T3-L1 mouse fibroblasts.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Caffeic Acids; Cell Differentiation; Dose-Response Relationship, Drug; Growth Inhibitors; Mice; Phenylethyl Alcohol | 2010 |
Antitumor progression potential of caffeic acid phenethyl ester involving p75(NTR) in C6 glioma cells.
Topics: Animals; Antibodies; Antineoplastic Agents; Biomarkers; Caffeic Acids; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; I-kappa B Kinase; Lung; Matrix Metalloproteinases; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Nerve Growth Factor; Neuroglia; Phenylethyl Alcohol; Phosphorylation; Rats; Receptor, Nerve Growth Factor; rhoB GTP-Binding Protein | 2010 |
Protective effects of caffeic acid phenethyl ester on retinal ischemia/reperfusion injury in rats.
Topics: Animals; Apoptosis; Caffeic Acids; Catalase; Electroretinography; Female; Glutathione Peroxidase; In Situ Nick-End Labeling; In Vitro Techniques; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Retina; Retinal Vessels; Superoxide Dismutase | 2010 |
The effects of caffeic acid phenethyl ester and melatonin on age-related vascular remodeling and cardiac damage.
Topics: Aging; Animals; Antioxidants; Aorta; Caffeic Acids; Catalase; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Assays; Glutathione; Heart; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Mitochondria; Myocardium; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2011 |
Antiangiogenic properties of an unusual benzo[k,l]xanthene lignan derived from CAPE (caffeic acid phenethyl ester).
Topics: Angiogenesis Inhibitors; Animals; Biomimetics; Caffeic Acids; Cell Line; Dose-Response Relationship, Drug; Endothelial Cells; Female; Granulosa Cells; Neovascularization, Physiologic; Phenylethyl Alcohol; Swine; Time Factors; Vascular Endothelial Growth Factor A | 2012 |
Cytotoxicity of arsenic trioxide is enhanced by (-)-epigallocatechin-3-gallate via suppression of ferritin in cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caffeic Acids; Catechin; Cell Line, Tumor; Cytotoxins; Drug Synergism; Ferritins; Heme Oxygenase (Decyclizing); HL-60 Cells; Humans; Neoplasms; Oxides; Phenylethyl Alcohol | 2011 |
Effects of caffeic acid phenethyl ester (CAPE) on hepatopulmonary syndrome.
Topics: Animals; Caffeic Acids; Hepatopulmonary Syndrome; Inflammation; Liver; Lung; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2011 |
Caffeic acid phenethyl ester protects against oxidative stress-related renal dysfunction in rats treated with cyclosporin A.
Topics: Acute Kidney Injury; Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Caffeic Acids; Creatinine; Cyclosporine; Disease Models, Animal; Drug Evaluation, Preclinical; Feeding Behavior; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2011 |
Inhibition of AMPK-associated autophagy enhances caffeic acid phenethyl ester-induced cell death in C6 glioma cells.
Topics: Adenine; AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Caffeic Acids; Cell Death; Cell Line, Tumor; Down-Regulation; Drug Synergism; Glioma; Humans; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Oxidative Stress; Phenylethyl Alcohol; Phosphorylation; Pyrazoles; Pyrimidines; Rats; RNA, Small Interfering | 2011 |
Caffeic acid phenethyl ester inhibits PDGF-induced proliferation of vascular smooth muscle cells via activation of p38 MAPK, HIF-1α, and heme oxygenase-1.
Topics: Animals; Caffeic Acids; Dose-Response Relationship, Drug; Heme Oxygenase-1; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Platelet-Derived Growth Factor; Propolis; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2011 |
Protective effects of CAPE on liver injury induced by CCL₄: an electron microscopy study.
Topics: Animals; Caffeic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Male; Microscopy, Electron, Transmission; Phenylethyl Alcohol; Rats; Rats, Wistar | 2011 |
Role of decoy molecules in neuronal ischemic preconditioning.
Topics: Animals; Animals, Newborn; Apoptosis; Caffeic Acids; Cerebral Cortex; Gene Expression Regulation; Ischemic Preconditioning; Neurons; NF-kappa B; Phenylethyl Alcohol; Rats; Receptors, Death Domain; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor Decoy Receptors | 2011 |
Caffeic acid phenethyl ester reduces spinal cord injury-evoked locomotor dysfunction.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cyclooxygenase 2; Down-Regulation; Female; Interleukin-1beta; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Rats; Rats, Wistar; Spinal Cord Injuries; Spinal Cord Regeneration; Thoracic Vertebrae; Transcription, Genetic | 2011 |
Effect of propolis and caffeic acid phenethyl ester (CAPE) on NFκB activation by HTLV-1 Tax.
Topics: Anti-Retroviral Agents; Caffeic Acids; Cell Line; Gene Products, tax; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; NF-kappa B; Phenylethyl Alcohol; Propolis; Transcriptional Activation | 2011 |
The metabolic bioactivation of caffeic acid phenethyl ester (CAPE) mediated by tyrosinase selectively inhibits glutathione S-transferase.
Topics: Caffeic Acids; Cell Line, Tumor; Enzyme Inhibitors; Glutathione Transferase; Humans; Melanoma; Monophenol Monooxygenase; Phenylethyl Alcohol | 2011 |
Caffeic acid phenethyl ester suppresses the production of adipocytokines, leptin, tumor necrosis factor -alpha and resistin, during differentiation to adipocytes in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Animals; Caffeic Acids; Cell Differentiation; Glycerolphosphate Dehydrogenase; Insulin Receptor Substrate Proteins; Leptin; Mice; Phenylethyl Alcohol; Propolis; Resistin; Resveratrol; Stilbenes; Triglycerides; Tumor Necrosis Factor-alpha | 2011 |
TNFα-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3K-NF-κB inhibitor, not mTOR inhibitor.
Topics: Aged; Apoptosis; Butadienes; Caffeic Acids; Caspase 3; Cells, Cultured; Chondrocytes; Chromones; Female; Humans; Middle Aged; Morpholines; NF-kappa B; Nitriles; Osteoarthritis; Phenylethyl Alcohol; Phosphoinositide-3 Kinase Inhibitors; Poly(ADP-ribose) Polymerases; Sirolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2012 |
Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders.
Topics: Aging; Antioxidants; Brain; Caffeic Acids; Catechin; Curcumin; Diet; Flavonoids; Neurodegenerative Diseases; Neuroprotective Agents; Phenols; Phenylethyl Alcohol; Polyphenols | 2010 |
Caffeic Acid Phenethyl Ester (CAPE) derived from propolis, a honeybee product, inhibits growth of breast cancer stem cells.
Topics: Agar; Animals; Apoptosis; Bees; Breast Neoplasms; Caffeic Acids; Cell Cycle; Cell Differentiation; Cell Proliferation; Cell Separation; Drug Screening Assays, Antitumor; Female; Honey; Humans; Mice; Neoplastic Stem Cells; Phenotype; Phenylethyl Alcohol; Propolis; Spheroids, Cellular; Tumor Cells, Cultured | 2012 |
Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells.
Topics: Antineoplastic Agents; Biological Availability; Caffeic Acids; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chromones; Curcuma; Curcumin; Drug Therapy, Combination; Enzyme Inhibitors; ErbB Receptors; Humans; Morpholines; NF-kappa B; Phenylethyl Alcohol; Phosphoinositide-3 Kinase Inhibitors; Phytotherapy; Plant Extracts; Pyrimidines; Quinazolines; Receptors, Fibroblast Growth Factor; Signal Transduction; Somatomedins; Tyrphostins | 2012 |
Caffeic acid phenethyl ester (CAPE), derived from a honeybee product propolis, exhibits a diversity of anti-tumor effects in pre-clinical models of human breast cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bees; Breast Neoplasms; Caffeic Acids; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Female; Humans; Mice; Mice, SCID; Neovascularization, Pathologic; NF-kappa B; Phenylethyl Alcohol; Propolis; Xenograft Model Antitumor Assays | 2011 |
Caffeic acid phenethyl ester prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration.
Topics: Animals; Blotting, Western; Brain; Caffeic Acids; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Degeneration; Neuroprotective Agents; Phenylethyl Alcohol | 2011 |
Caffeic acid phenethyl ester suppresses eotaxin secretion and nuclear p-STAT6 in human lung fibroblast cells.
Topics: Caffeic Acids; Cell Line; Cell Nucleus; Cell Survival; Chemokine CCL11; DNA; Fibroblasts; Humans; Interleukin-4; Phenylethyl Alcohol; Phosphorylation; STAT6 Transcription Factor; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2011 |
Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties.
Topics: Antioxidants; Caffeic Acids; Emulsions; Linoleic Acid; Lipid Peroxidation; Phenylethyl Alcohol; Plant Extracts; Polyphenols; Propolis | 2011 |
Protective effects of caffeic acid phenethyl ester (CAPE) on intestinal damage in necrotizing enterocolitis.
Topics: Administration, Oral; Animals; Animals, Newborn; Apoptosis; Caffeic Acids; Caspase 9; Cell Count; Disease Models, Animal; Enterocolitis, Necrotizing; Ileum; Immunohistochemistry; In Situ Nick-End Labeling; NF-kappa B; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome; Xanthine Oxidase | 2011 |
Nuclear factor-kappa β regulates Notch signaling in production of proinflammatory cytokines and nitric oxide in murine BV-2 microglial cells.
Topics: Animals; Blotting, Western; Caffeic Acids; Cell Line; Cell Separation; Cytokines; Cytotoxins; Flow Cytometry; Fluorescent Antibody Technique; Inflammation; Mice; Microglia; NF-kappa B; Nitric Oxide; Phenylethyl Alcohol; Real-Time Polymerase Chain Reaction; Receptors, Notch; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2011 |
The efficiency of CAPE on retardation of hepatic fibrosis in biliary obstructed rats.
Topics: Animals; Caffeic Acids; Cell Proliferation; Cholestasis; Glutathione Peroxidase; Hydroxyproline; Immunohistochemistry; In Situ Nick-End Labeling; Liver; Liver Cirrhosis; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2011 |
Caffeic acid phenethyl ester modulates gentamicin-induced oxidative nephrotoxicity in kidney of rats.
Topics: Animals; Anti-Bacterial Agents; Caffeic Acids; Creatinine; Female; Gentamicins; Kidney; Kidney Diseases; Lipid Peroxidation; Nitric Oxide; Oxidoreductases; Phenylethyl Alcohol; Rats; Rats, Wistar | 2012 |
Effect of ionic liquids on enzymatic synthesis of caffeic acid phenethyl ester.
Topics: Caffeic Acids; Enzyme Activation; Ionic Liquids; Lipase; Phenylethyl Alcohol | 2012 |
Role of interleukin 1 beta in esophageal squamous cell carcinoma.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Disease Progression; Drug Resistance, Neoplasm; Esophageal Neoplasms; Humans; Interleukin-1beta; Male; Mice; Mice, Nude; Middle Aged; NF-kappa B; Phenylethyl Alcohol; Prognosis; Radiation Tolerance; Survival Analysis | 2012 |
Stability of caffeic acid phenethyl amide (CAPA) in rat plasma.
Topics: Amides; Animals; Caffeic Acids; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Kinetics; Male; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Temperature | 2012 |
Caffeic acid phenethyl ester inhibits proliferation and migration, and induces apoptosis in platelet-derived growth factor-BB-stimulated human coronary smooth muscle cells.
Topics: Apoptosis; Becaplermin; Caffeic Acids; Caspases; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Vessels; Cytochromes c; Humans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-sis | 2012 |
Protective role of caffeic acid on lambda cyhalothrin-induced changes in sperm characteristics and testicular oxidative damage in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Body Weight; Caffeic Acids; Cell Survival; Glutathione; Lipid Peroxidation; Male; Nitriles; Oxidative Stress; Phenylethyl Alcohol; Pyrethrins; Rats; Rats, Wistar; Sperm Count; Sperm Motility; Spermatozoa; Testis | 2012 |
Catechols in caffeic acid phenethyl ester are essential for inhibition of TNF-mediated IP-10 expression through NF-κB-dependent but HO-1- and p38-independent mechanisms in mouse intestinal epithelial cells.
Topics: Animals; Caffeic Acids; Catechols; Cell Line; Chemokine CXCL10; Epithelial Cells; Heme Oxygenase-1; I-kappa B Proteins; Intestinal Mucosa; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Phosphorylation; Signal Transduction; Transcription Factors; Tumor Necrosis Factor-alpha | 2011 |
Caffeic acid phenethyl ester (CAPE) prevents methotrexate-induced hepatorenal oxidative injury in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Caffeic Acids; Chemical and Drug Induced Liver Injury; Female; Glutathione; Interleukin-1beta; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tumor Necrosis Factor-alpha | 2011 |
Neuroprotective effects of caffeic acid phenethyl ester on experimental traumatic brain injury in rats.
Topics: Animals; Brain; Brain Injuries; Caffeic Acids; Caspase 3; Catalase; Glutathione Peroxidase; Male; Malondialdehyde; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2012 |
Caffeic Acid phenethyl ester protects blood-brain barrier integrity and reduces contusion volume in rodent models of traumatic brain injury.
Topics: Animals; Blood-Brain Barrier; Brain Injuries; Caffeic Acids; Disease Models, Animal; Fluorescent Antibody Technique; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Recovery of Function | 2012 |
Caffeic Acid phenethyl ester possessing various immunomodulatory effects is a potentially effective therapy for asthma.
Topics: Asthma; Caffeic Acids; Cytokines; Female; Humans; Male; Phenylethyl Alcohol; Th1 Cells; Th2 Cells | 2011 |
The immunoregulatory effects of caffeic acid phenethyl ester on the cytokine secretion of peripheral blood mononuclear cells from asthmatic children.
Topics: Asthma; Caffeic Acids; Child; Child, Preschool; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukocytes, Mononuclear; Male; Phenylethyl Alcohol; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells | 2011 |
Caffeic acid phenethyl ester extends survival of a mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Transgenic; Neuroprotective Agents; Phenylethyl Alcohol; Survival Rate; Treatment Outcome | 2012 |
Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving haem oxygenase-1 and brain-derived neurotrophic factor.
Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Caffeic Acids; Disease Models, Animal; Dopaminergic Neurons; Enzyme Induction; Heme Oxygenase-1; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitric Oxide; Parkinsonian Disorders; Phenylethyl Alcohol; Rats; Rats, Wistar; Substantia Nigra | 2012 |
Cancer prevention mediated by caffeic acid phenethyl ester involves cyp2b1/2 modulation in hepatocarcinogenesis.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Caffeic Acids; Carcinogenicity Tests; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochromes; Diethylnitrosamine; Disease Models, Animal; Liver Neoplasms, Experimental; Male; Phenylethyl Alcohol; Proadifen; Rats; Rats, Inbred F344; Steroid Hydroxylases | 2012 |
Caffeic acid phenethyl ester causes p21 induction, Akt signaling reduction, and growth inhibition in PC-3 human prostate cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Synergism; Humans; Male; Microarray Analysis; p21-Activated Kinases; Phenylethyl Alcohol; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction | 2012 |
Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes.
Topics: Amides; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Caffeic Acids; Humans; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Neutrophils; Phenylethyl Alcohol; Structure-Activity Relationship | 2012 |
Effect of caffeic acid phenethyl ester (CAPE) on H₂O₂ induced oxidative and inflammatory responses in human middle ear epithelial cells.
Topics: Antioxidants; Blotting, Western; Caffeic Acids; Cell Culture Techniques; Cytokines; Ear, Middle; Epithelial Cells; Flow Cytometry; Humans; Hydrogen Peroxide; Inflammation; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction | 2012 |
Role of caffeic acid phenethyl ester on mitomycin C induced clastogenesis: analysis of chromosome aberrations, micronucleus, mitotic index and adenosine deaminase activity in vivo.
Topics: Adenosine Deaminase; Administration, Oral; Animals; Bone Marrow Cells; Caffeic Acids; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mitotic Index; Mutagenesis; Phenylethyl Alcohol; Reactive Oxygen Species; Spleen; Thymus Gland | 2012 |
Protective effect of caffeic acid phenethyl ester against cadmium-induced renal damage in mice.
Topics: Animals; Antioxidants; Cadmium; Caffeic Acids; Carcinogens; Catalase; Environmental Pollutants; Glutathione; Kidney; Male; Mice; Oxidative Stress; Phenylethyl Alcohol; Superoxide Dismutase; Zinc | 2012 |
Vimentin and PSF act in concert to regulate IbeA+ E. coli K1 induced activation and nuclear translocation of NF-κB in human brain endothelial cells.
Topics: Active Transport, Cell Nucleus; Blood-Brain Barrier; Brain; Caffeic Acids; Cell Movement; Cells, Cultured; Endothelial Cells; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Gene Knockdown Techniques; Host-Pathogen Interactions; Humans; Membrane Proteins; Meningitis, Bacterial; Microvessels; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neutrophil Infiltration; Neutrophils; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Protein Binding; Protein Interaction Domains and Motifs; PTB-Associated Splicing Factor; RNA-Binding Proteins; Sequence Deletion; Signal Transduction; Tubulin; Vimentin | 2012 |
Melatonin and CAPE are able to prevent the liver from oxidative damage in rats: an ultrastructural and biochemical study.
Topics: Age Factors; Animals; Antioxidants; Caffeic Acids; Catalase; Glutathione; Glutathione Peroxidase; Liver; Liver Diseases; Male; Malondialdehyde; Melatonin; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2012 |
Caffeic acid phenethyl ester suppresses the proliferation of human prostate cancer cells through inhibition of p70S6K and Akt signaling networks.
Topics: Animals; Caffeic Acids; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Down-Regulation; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oncogene Protein v-akt; Phenylethyl Alcohol; Prostatic Neoplasms; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Xenograft Model Antitumor Assays | 2012 |
Caffeic acid phenethyl ester reduces the activation of the nuclear factor κB pathway by high-fat diet-induced obesity in mice.
Topics: Animals; Blood Glucose; Caffeic Acids; Dietary Fats; Enzyme-Linked Immunosorbent Assay; Glucose Tolerance Test; Inflammation; Insulin; Male; Mice; NF-kappa B; Obesity; Phenylethyl Alcohol; Signal Transduction | 2012 |
Simultaneous determination of caffeic acid phenethyl ester and its metabolite caffeic acid in dog plasma using liquid chromatography tandem mass spectrometry.
Topics: Animals; Caffeic Acids; Chemical Precipitation; Chromatography, Liquid; Dogs; Drug Stability; Phenylethyl Alcohol; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
Caffeic acid phenethyl ester attenuates IgE-induced immediate allergic reaction.
Topics: Adenosine; Animals; Anti-Allergic Agents; Caffeic Acids; Capillary Permeability; Guinea Pigs; Histamine; Histamine Release; Hypersensitivity; Immunoglobulin E; Leukotrienes; Male; Mast Cells; Passive Cutaneous Anaphylaxis; Phenylethyl Alcohol; Rats; Rats, Wistar; Serotonin; Vasoconstriction | 2013 |
Caffeic acid phenethyl ester prevents detrimental effects of remote ischemia-reperfusion injury on healing of colonic anastomoses.
Topics: Anastomosis, Surgical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Colon; Cytokines; Drug Evaluation, Preclinical; Hydroxyproline; Laparotomy; Male; Malondialdehyde; Mesenteric Artery, Superior; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Surgical Wound Dehiscence; Wound Healing; Xanthine Oxidase | 2013 |
Caffeic acid phenethyl ester effects in the kidney during ischemia and reperfusion in rats anesthetized with isoflurane.
Topics: Anesthetics, Inhalation; Animals; Biomarkers; Caffeic Acids; Creatinine; Disease Models, Animal; Isoflurane; Kidney; Male; Necrosis; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Time Factors | 2012 |
Caffeic acid phenethyl ester protects 661W cells from H2O2-mediated cell death and enhances electroretinography response in dim-reared albino rats.
Topics: Albinism; Animals; Caffeic Acids; Cell Death; Electroretinography; Eye Proteins; Fatty Acids, Omega-3; Gene Expression; Heme Oxygenase-1; Hydrogen Peroxide; Intercellular Adhesion Molecule-1; L-Lactate Dehydrogenase; Light; Lipoxygenases; NF-kappa B; Phenylethyl Alcohol; Photoreceptor Cells, Vertebrate; Propolis; Protective Agents; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2012 |
Impairment of antioxidant defenses as a contributor to arsenite-induced cell transformation.
Topics: Antioxidants; Arsenites; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dicumarol; Environmental Pollutants; Ferritins; Gene Expression; Genes, p53; Humans; Intracellular Signaling Peptides and Proteins; Models, Biological; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Phenylethyl Alcohol; Proto-Oncogene Proteins; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Suppressor Protein p53 | 2012 |
Early treatment of radiation-induced heart damage in rats by caffeic acid phenethyl ester.
Topics: Animals; Biomarkers; Caffeic Acids; Heart; Heart Injuries; Male; Oxidative Stress; Phenylethyl Alcohol; Radiation Injuries; Rats; Rats, Sprague-Dawley; Time Factors | 2012 |
Impact of lysophosphatidylcholine on the plasminogen activator system in cultured vascular smooth muscle cells.
Topics: Animals; Benz(a)Anthracenes; Caffeic Acids; Cells, Cultured; Genistein; Lipoproteins, LDL; Lysophosphatidylcholines; Muscle, Smooth, Vascular; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Plasminogen Activator Inhibitor 1; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tissue Plasminogen Activator; Transcription, Genetic; Up-Regulation; Vitamin E | 2012 |
Not only melatonin but also caffeic acid phenethyl ester protects kidneys against aging-related oxidative damage in Sprague Dawley rats.
Topics: Aging; Animals; Antioxidants; Caffeic Acids; Cytoprotection; Kidney; Male; Melatonin; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2012 |
CAPE suppresses VEGFR-2 activation, and tumor neovascularization and growth.
Topics: Angiogenesis Inhibitors; Animals; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms; Neovascularization, Pathologic; Phenylethyl Alcohol; Tumor Burden; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Caffeic acid phenethyl ester protects kidneys against acetylsalicylic acid toxicity in rats.
Topics: Acute Kidney Injury; Animals; Aspirin; Caffeic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Kidney; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar | 2012 |
Caffeic acid phenethyl ester ameliorates cadmium-induced kidney mitochondrial injury.
Topics: Acute Kidney Injury; Animals; Cadmium; Caffeic Acids; Environmental Pollutants; Male; Mitochondria; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar | 2012 |
Comparative analysis of the protective effects of caffeic acid phenethyl ester (CAPE) on pulmonary contusion lung oxidative stress and serum copper and zinc levels in experimental rat model.
Topics: Analysis of Variance; Animals; Blood Gas Analysis; Caffeic Acids; Catalase; Contusions; Copper; Disease Models, Animal; Humans; Lung; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Zinc | 2013 |
Effects of caffeic acid phenethyl ester on anastomotic healing in secondary peritonitis.
Topics: Anastomosis, Surgical; Animals; Caffeic Acids; Colon; Disease Models, Animal; Glutathione; Hydroxyproline; Male; Malondialdehyde; Peritonitis; Peroxidase; Phenylethyl Alcohol; Pressure; Rats; Rats, Wistar; Stress, Mechanical; Superoxide Dismutase; Wound Healing | 2012 |
Inhibition of Ca(2+) release-activated Ca(2+) channel (CRAC) by curcumin and caffeic acid phenethyl ester (CAPE) via electrophilic addition to a cysteine residue of Orai1.
Topics: Caffeic Acids; Calcium; Calcium Channels; Curcumin; Cysteine; HEK293 Cells; Humans; Mutation; ORAI1 Protein; Phenylethyl Alcohol | 2012 |
Caffeic acid phenethyl ester suppresses the production of pro-inflammatory cytokines in hypertrophic adipocytes through lipopolysaccharide-stimulated macrophages.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Line; Cytokines; Gene Expression Regulation; Hypertrophy; Lipopolysaccharides; Macrophages; Mice; Phenylethyl Alcohol; RNA, Messenger | 2012 |
Ethanolic extract of propolis, chrysin, CAPE inhibit human astroglia cells.
Topics: Apoptosis; Astrocytes; Caffeic Acids; Cell Line; Cell Survival; Cytotoxins; Ethanol; Flavonoids; Humans; Phenylethyl Alcohol; Propolis | 2012 |
Caffeic acid phenethyl ester alleviates mesenteric ischemia/reperfusion injury.
Topics: Animals; Antioxidants; Caffeic Acids; Cytokines; Glutathione Peroxidase; Intestine, Small; Male; Malondialdehyde; Models, Animal; Nitrates; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion Injury; Xanthine Oxidase | 2012 |
Synthesis and antiradical/antioxidant activities of caffeic acid phenethyl ester and its related propionic, acetic, and benzoic acid analogues.
Topics: Acetic Acid; Antioxidants; Benzoic Acid; Caffeic Acids; Carbon; Lipid Peroxidation; Oxidation-Reduction; Phenylethyl Alcohol; Propionates; Propolis | 2012 |
Induction of apoptosis by a potent caffeic acid derivative, caffeic acid undecyl ester, is mediated by mitochondrial damage in NALM-6 human B cell leukemia cells.
Topics: Analysis of Variance; Apoptosis; Caffeic Acids; Caspase 3; Cell Survival; Down-Regulation; Genes, bcl-2; Humans; Inhibitory Concentration 50; Leukemia, B-Cell; Lymphocytes; Membrane Potential, Mitochondrial; Phenylethyl Alcohol; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2013 |
Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Line; Chromatography, Gas; Disease Models, Animal; Gene Expression Regulation; HEK293 Cells; Humans; Inflammation; Interferon Regulatory Factor-3; Lipopolysaccharides; Lymphocyte Antigen 96; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Signal Transduction; Tandem Mass Spectrometry; Toll-Like Receptor 4 | 2013 |
Caffeic acid phenethyl ester protects against the dopaminergic neuronal loss induced by 6-hydroxydopamine in rats.
Topics: Adrenergic Agents; Animals; Antioxidants; Caffeic Acids; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Free Radical Scavengers; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Phenylethyl Alcohol; Rats; Rats, Wistar | 2013 |
Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells.
Topics: Acrolein; ADAM Proteins; ADAM10 Protein; Amyloid Precursor Protein Secretases; Animals; Antioxidants; Aspartic Acid Endopeptidases; Caffeic Acids; Cell Line; Cell Survival; Glutathione; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; MAP Kinase Signaling System; Membrane Proteins; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; Phenylethyl Alcohol; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species | 2013 |
Caffeic acid phenethyl ester induces adrenoleukodystrophy (Abcd2) gene in human X-ALD fibroblasts and inhibits the proinflammatory response in Abcd1/2 silenced mouse primary astrocytes.
Topics: Acetyltransferases; Adrenoleukodystrophy; Animals; Astrocytes; ATP Binding Cassette Transporter, Subfamily D; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Caffeic Acids; Cells, Cultured; Child; Fatty Acid Elongases; Fibroblasts; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol | 2013 |
Antibacterial activity of Sonoran propolis and some of its constituents against clinically significant Vibrio species.
Topics: Anti-Bacterial Agents; Caffeic Acids; Flavonoids; Mexico; Microbial Sensitivity Tests; Phenylethyl Alcohol; Propolis; Vibrio; Vibrio cholerae O1 | 2013 |
The protective effects of caffeic acid phenethyl ester in isoniazid and ethambutol-induced ocular toxicity of rats.
Topics: Animals; Caffeic Acids; Ethambutol; Isoniazid; Male; Malondialdehyde; Optic Nerve Diseases; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley; Retinal Diseases; Retinal Ganglion Cells; Superoxide Dismutase | 2013 |
Optimization of lipase-catalyzed synthesis of caffeic acid phenethyl ester in ionic liquids by response surface methodology.
Topics: Caffeic Acids; Enzymes, Immobilized; Fungal Proteins; Hot Temperature; Imidazoles; Lipase; Phenylethyl Alcohol; Sulfonamides | 2013 |
The effect of caffeic acid phenethyl ester analogues in a modified resistant hepatocyte model.
Topics: 2-Acetylaminofluorene; Acetanilides; Animals; Anticarcinogenic Agents; Antioxidants; Caffeic Acids; Carcinogens; Cell Division; Cinnamates; Diethylnitrosamine; Drug Evaluation, Preclinical; Drug Resistance; Glutathione S-Transferase pi; Hepatectomy; Hepatocytes; Ki-67 Antigen; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Molecular Structure; Phenylethyl Alcohol; Precancerous Conditions; Rats; Rats, Inbred F344; Transcription Factor RelA | 2013 |
Electrophysiological and mechanical effects of caffeic acid phenethyl ester, a novel cardioprotective agent with antiarrhythmic activity, in guinea-pig heart.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeic Acids; Cardiotonic Agents; Electrophysiological Phenomena; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Papillary Muscles; Phenylethyl Alcohol | 2013 |
Caffeic acid phenethyl ester modulates aflatoxin B1-induced hepatotoxicity in rats.
Topics: Aflatoxin B1; Animals; Apoptosis; Caffeic Acids; Cytoprotection; Dose-Response Relationship, Drug; Free Radicals; Hepatocytes; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Structure-Activity Relationship | 2013 |
Caffeic acid phenylethyl ester and MG132, two novel nonconventional chemotherapeutic agents, induce apoptosis of human leukemic cells by disrupting mitochondrial function.
Topics: Adolescent; Adult; Antineoplastic Agents; Apoptosis; Caffeic Acids; Child; Child, Preschool; Drugs, Investigational; Female; Humans; Leukemia; Leupeptins; Male; Middle Aged; Mitochondria; Phenylethyl Alcohol; Tumor Cells, Cultured; Young Adult | 2014 |
Class 3 inhibition of hERG K+ channel by caffeic acid phenethyl ester (CAPE) and curcumin.
Topics: Action Potentials; Caffeic Acids; Curcumin; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Kinetics; Phenylethyl Alcohol; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2013 |
The effects of caffeic acid phenethyl ester in acute methanol toxicity on rat retina and optic nerve.
Topics: Alcohol Dehydrogenase; Animals; Antidotes; Caffeic Acids; Ethanol; Fomepizole; Humans; Male; Methanol; Molecular Docking Simulation; Optic Nerve; Oxidative Stress; Phenylethyl Alcohol; Pyrazoles; Rats; Rats, Sprague-Dawley; Retina | 2013 |
Caffeic acid phenethyl ester as an adjuvant therapy for advanced prostate cancer.
Topics: Caffeic Acids; Chemotherapy, Adjuvant; Humans; Male; Phenylethyl Alcohol; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt | 2013 |
Caffeic acid phenethyl ester induces E2F-1-mediated growth inhibition and cell-cycle arrest in human cervical cancer cells.
Topics: Apoptosis; Caffeic Acids; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; E2F1 Transcription Factor; Female; Gene Knockdown Techniques; HeLa Cells; Humans; Phenylethyl Alcohol; Promoter Regions, Genetic; Uterine Cervical Neoplasms | 2013 |
PAK1-deficiency/down-regulation reduces brood size, activates HSP16.2 gene and extends lifespan in Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caffeic Acids; Down-Regulation; Green Fluorescent Proteins; Heat-Shock Proteins; Longevity; p21-Activated Kinases; Phenylethyl Alcohol; Phenylpropionates; Protein Kinase Inhibitors; Recombinant Fusion Proteins; Reproduction; Signal Transduction | 2013 |
Increase of TNFα-stimulated osteoarthritic chondrocytes apoptosis and decrease of matrix metalloproteinases 9 by NF-κB inhibition.
Topics: Aged; Apoptosis; Caffeic Acids; Calcium; Cells, Cultured; Chondrocytes; Drug Evaluation, Preclinical; Female; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; NF-kappa B; Osteoarthritis; Phenylethyl Alcohol; Tumor Necrosis Factor-alpha | 2013 |
Effect of caffeic acid phenethyl ester on intra-abdominal adhesion in rats.
Topics: Abdominal Cavity; Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Disease Models, Animal; Female; Infusions, Parenteral; Laparotomy; Phenylethyl Alcohol; Rats; Tissue Adhesions; Uterus | 2013 |
NMR metabolomics analysis of the effects of 5-lipoxygenase inhibitors on metabolism in glioblastomas.
Topics: Antineoplastic Agents; Arachidonate 5-Lipoxygenase; Caffeic Acids; Cell Line, Tumor; Drug Screening Assays, Antitumor; Free Radical Scavengers; Glioblastoma; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxyurea; Leukotrienes; Lipid Metabolism; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Metabolome; Metabolomics; Phenylethyl Alcohol; Principal Component Analysis | 2013 |
Separation and purification of the antioxidant compounds, caffeic acid phenethyl ester and caffeic acid from mushrooms by molecularly imprinted polymer.
Topics: Adsorption; Agaricales; Antioxidants; Caffeic Acids; Molecular Imprinting; Phenylethyl Alcohol; Polymers; Solid Phase Extraction | 2013 |
Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis.
Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Caffeic Acids; Cell Survival; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; Gene Silencing; Hydroxyproline; Intubation, Intratracheal; Lipid Peroxidation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Oxidoreductases; Phenylethyl Alcohol; Pulmonary Fibrosis; Reactive Oxygen Species | 2013 |
Ameliorative effects of caffeic acid phenethyl ester on an eccentric exercise-induced skeletal muscle injury by down-regulating NF-κb mediated inflammation.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Creatine Kinase; Cyclooxygenase 2; Down-Regulation; Inflammation; Male; Muscle, Skeletal; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Phenylethyl Alcohol; Physical Conditioning, Animal; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar | 2013 |
Protective effects of caffeic acid phenethyl ester on dose-dependent intoxication of rats with paraquat.
Topics: Animals; Antioxidants; Caffeic Acids; Dose-Response Relationship, Drug; Female; Pancreas; Paraquat; Phenylethyl Alcohol; Rats; Rats, Wistar | 2015 |
Effects of caffeic acid phenethyl ester (CAPE) on membrane potential and intracellular calcium in human endothelial cells.
Topics: Caffeic Acids; Calcium; Cell Proliferation; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Membrane Potentials; Nitrogen Oxides; Phenylethyl Alcohol | 2013 |
Caffeic acid phenethyl ester (CAPE), an active component of propolis, inhibits Helicobacter pylori peptide deformylase activity.
Topics: Amidohydrolases; Binding Sites; Caffeic Acids; Helicobacter pylori; Phenylethyl Alcohol; Propolis; Protein Binding | 2013 |
Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of Akt signaling.
Topics: Apoptosis; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Fluorouracil; Humans; Models, Biological; Mouth Neoplasms; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Stem Cell Assay | 2013 |
Caffeic acid phenethyl ester suppresses melanoma tumor growth by inhibiting PI3K/AKT/XIAP pathway.
Topics: Animals; Apoptosis; Caffeic Acids; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Melanoma; Mice; Oncogene Protein v-akt; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Signal Transduction; Skin Neoplasms; X-Linked Inhibitor of Apoptosis Protein | 2013 |
Caffeic acid phenethyl ester inhibits endothelial tissue factor expression.
Topics: Aorta; Caffeic Acids; Cells, Cultured; Endothelial Cells; Fibrinolytic Agents; Humans; Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; RNA, Messenger; Thromboplastin; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2013 |
Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line.
Topics: 3' Untranslated Regions; Aluminum; Animals; Caffeic Acids; Cell Line; Down-Regulation; Epigenesis, Genetic; Gene Expression; Membrane Glycoproteins; Mice; Microglia; MicroRNAs; NF-kappa B; Phagocytosis; Phenylethyl Alcohol; Receptors, Immunologic | 2013 |
Protective and anti-angiopathy effects of caffeic acid phenethyl ester against induced type 1 diabetes in vivo.
Topics: Animals; Blood Glucose; Caffeic Acids; Cells, Cultured; Diabetes Mellitus, Experimental; Endostatins; Humans; Insulin; Interferon-gamma; Interleukin-1beta; Islets of Langerhans; Male; Matrix Metalloproteinase 9; Mice; Neovascularization, Pathologic; Nitric Oxide; Phenylethyl Alcohol; Vesicular Transport Proteins | 2013 |
Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Docetaxel; Drug Synergism; Estrogen Receptor alpha; Estrogen Receptor beta; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Inhibitory Concentration 50; Male; Paclitaxel; Phenylethyl Alcohol; Prostatic Neoplasms; Taxoids | 2013 |
CAPE promotes TRAIL-induced apoptosis through the upregulation of TRAIL receptors via activation of p38 and suppression of JNK in SK-Hep1 hepatocellular carcinoma cells.
Topics: Animals; Apoptosis; Bees; Caffeic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Propolis; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation | 2013 |
The protective effects of caffeic acid phenethyl ester against toluene-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Caffeic Acids; Catalase; Creatinine; Dose-Response Relationship, Drug; Glutathione Peroxidase; Kidney; Male; Malondialdehyde; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Toluene | 2016 |
[Impact of NF-kappaB inhibitor on STAT3 translocation in PC-3 prostate cancer cell line].
Topics: Caffeic Acids; Cell Line, Tumor; Humans; Interleukin-6; Male; NF-kappa B; Phenylethyl Alcohol; Prostatic Neoplasms; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha | 2013 |
Strategies for ascertaining the interference of phase II metabolites co-eluting with parent compounds using LC-MS/MS.
Topics: Caffeic Acids; Chromatography, High Pressure Liquid; Humans; Phenylethyl Alcohol; Reproducibility of Results; Tandem Mass Spectrometry | 2013 |
Design, synthesis and pharmacological evaluation of (E)-3,4-dihydroxy styryl sulfonamides derivatives as multifunctional neuroprotective agents against oxidative and inflammatory injury.
Topics: Animals; Blood-Brain Barrier; Caffeic Acids; Cell Line, Tumor; Drug Design; Free Radical Scavengers; Mice; Microglia; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Stereoisomerism; Sulfonamides | 2013 |
Caffeic acid phenethyl ester activation of Nrf2 pathway is enhanced under oxidative state: structural analysis and potential as a pathologically targeted therapeutic agent in treatment of colonic inflammation.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Immunoprecipitation; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Structure-Activity Relationship | 2013 |
Caffeic acid phenethyl ester suppresses oxidative stress in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Caffeic Acids; Mice; Molecular Structure; Oxidative Stress; Phenylethyl Alcohol; PPAR gamma; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase | 2013 |
Development and validation of an LCMS method to determine the pharmacokinetic profiles of caffeic acid phenethyl amide and caffeic acid phenethyl ester in male Sprague-Dawley rats.
Topics: Animals; Caffeic Acids; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Limit of Detection; Linear Models; Male; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2014 |
Caffeic acid phenethyl ester prevents apoptotic cell death in the developing rat brain after pentylenetetrazole-induced status epilepticus.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Brain; Caffeic Acids; Caspase 3; Convulsants; Disease Models, Animal; In Situ Nick-End Labeling; Male; Neurons; Neuroprotective Agents; Pentylenetetrazole; Phenylethyl Alcohol; Rats; Rats, Wistar; Status Epilepticus | 2013 |
Theoretical, antioxidant and cytotoxic activities of caffeic acid phenethyl ester and chrysin.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Caffeic Acids; Cell Proliferation; Cell Survival; Computational Biology; Flavonoids; Free Radical Scavengers; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Models, Chemical; Phenylethyl Alcohol; Quantum Theory; Structure-Activity Relationship | 2014 |
Propolis augments apoptosis induced by butyrate via targeting cell survival pathways.
Topics: Apoptosis; Butyrates; Caffeic Acids; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Phenylethyl Alcohol; Phosphorylation; Propolis; STAT Transcription Factors | 2013 |
Caffeic acid phenethyl ester (CAPE) protects against acute urogenital injury following pneumoperitoneum in the rat.
Topics: Acute Kidney Injury; Animals; Caffeic Acids; Drug Evaluation, Preclinical; Genital Diseases, Male; Laparoscopy; Male; Phenylethyl Alcohol; Pneumoperitoneum, Artificial; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Testis | 2014 |
Influence of caffeic acid phenethyl ester on bone healing in a rat model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biocompatible Materials; Bone Regeneration; Caffeic Acids; Calcium Phosphates; Fibroblasts; Injections, Intraperitoneal; Male; Osteoblasts; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Skull | 2013 |
Impact of caffeic acid phenethyl ester treatment on vancomycin-induced pancreatic damage in rats.
Topics: Acute Disease; Alkaline Phosphatase; Amylases; Animals; Antioxidants; Caffeic Acids; gamma-Glutamyltransferase; Lipase; Male; Pancreas; Pancreatitis; Phenylethyl Alcohol; Rats; Rats, Wistar; Vancomycin | 2016 |
Protective effects of caffeic acid phenethyl ester on ifosfamide-induced central neurotoxicity in rats.
Topics: Animals; Antioxidants; Brain; Caffeic Acids; Catalase; Ifosfamide; Immunohistochemistry; Lipid Peroxidation; Male; Malondialdehyde; Neurotoxicity Syndromes; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Protein Carbonylation; Rats; Rats, Wistar | 2016 |
Caffeic acid phenethyl ester downregulates phospholipase D1 via direct binding and inhibition of NFκB transactivation.
Topics: Antineoplastic Agents; Brain Neoplasms; Caffeic Acids; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; NF-kappa B; Phenylethyl Alcohol; Phospholipase D; Promoter Regions, Genetic; Propolis; Transcriptional Activation | 2013 |
Phenolic profile and antioxidant activity of Serbian polyfloral honeys.
Topics: Abscisic Acid; Antioxidants; Caffeic Acids; Chlorogenic Acid; Ellagic Acid; Flavonoids; Food Analysis; Honey; Hydroxybenzoates; Phenols; Phenylethyl Alcohol; Quinic Acid; Serbia | 2014 |
Arsenic augments the uptake of oxidized LDL by upregulating the expression of lectin-like oxidized LDL receptor in mouse aortic endothelial cells.
Topics: Acetylcysteine; Animals; Aorta; Arsenites; Atherosclerosis; Caffeic Acids; Cell Line; Endothelial Cells; Lipoproteins, LDL; Mice; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Reactive Oxygen Species; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Sodium Compounds; Up-Regulation | 2013 |
Enhanced antioxidant effect of caffeic acid phenethyl ester and Trolox in combination against radiation induced-oxidative stress.
Topics: Animals; Antioxidants; Biphenyl Compounds; Caffeic Acids; Cell Line; Cell Survival; Chromans; Free Radical Scavengers; Gamma Rays; Glutathione Disulfide; Lipid Peroxidation; Male; Mice; Microsomes, Liver; Oxidative Stress; Phenylethyl Alcohol; Picrates; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Thiobarbituric Acid Reactive Substances | 2014 |
Caffeic acid phenethyl ester inhibits diesel exhaust particle-induced inflammation of human middle ear epithelial cells via NOX4 inhibition.
Topics: Blotting, Western; Caffeic Acids; Cells, Cultured; Epithelial Cells; Humans; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Otitis Media; Oxidative Stress; Particulate Matter; Phenylethyl Alcohol; RNA, Messenger; Up-Regulation; Vehicle Emissions | 2013 |
Protective effects of caffeic acid phenethyl ester on the dose-dependent acute nephrotoxicity with paraquat in a rat model.
Topics: Animals; Antioxidants; Caffeic Acids; Female; Herbicides; Humans; Kidney; Kidney Diseases; Oxidation-Reduction; Paraquat; Phenylethyl Alcohol; Rats; Rats, Wistar | 2015 |
Effect of caffeic acid phenethyl ester on myringosclerosis development in the tympanic membrane of rat.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Proliferation; Fibroblasts; Inflammation; Microscopy; Myringosclerosis; Otologic Surgical Procedures; Phenylethyl Alcohol; Random Allocation; Rats, Wistar; Tympanic Membrane | 2015 |
Anticancer effects of thymoquinone, caffeic acid phenethyl ester and resveratrol on A549 non-small cell lung cancer cells exposed to benzo(a)pyrene.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzo(a)pyrene; Benzoquinones; Caffeic Acids; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cytokines; Glutathione; Humans; Lung Neoplasms; Malondialdehyde; NF-kappa B; Nitric Oxide; Phenylethyl Alcohol; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2013 |
Inhibitory effects of caffeic acid phenethyl ester derivatives on replication of hepatitis C virus.
Topics: Antiviral Agents; Caffeic Acids; Hepacivirus; Phenylethyl Alcohol; RNA, Viral; Structure-Activity Relationship; Virus Replication | 2013 |
Caffeic acid phenethyl ester attenuates pro-inflammatory and fibrogenic phenotypes of LPS-stimulated hepatic stellate cells through the inhibition of NF-κB signaling.
Topics: Animals; Caffeic Acids; Collagen Type I; Collagen Type I, alpha 1 Chain; Hepatic Stellate Cells; Humans; Inflammation; Lipopolysaccharides; Liver Cirrhosis; NF-kappa B; Phenylethyl Alcohol; Rats; Signal Transduction; Toll-Like Receptor 4; Transforming Growth Factor beta | 2014 |
Structural basis for the inhibition of AKR1B10 by caffeic acid phenethyl ester (CAPE).
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Caffeic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Phenylethyl Alcohol; Structure-Activity Relationship | 2014 |
CAPE promotes the expansion of human umbilical cord blood-derived hematopoietic stem and progenitor cells in vitro.
Topics: Caffeic Acids; Cells, Cultured; Flow Cytometry; Hematopoietic Stem Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; In Vitro Techniques; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Factor; Umbilical Cord; Up-Regulation | 2014 |
Caffeic acid phenethyl ester, a 5-lipoxygenase enzyme inhibitor, alleviates diabetic atherosclerotic manifestations: effect on vascular reactivity and stiffness.
Topics: Animals; Aorta; Atherosclerosis; Blood Pressure; Body Weight; Caffeic Acids; Diabetes Complications; Immunohistochemistry; Insulin; Lipoxygenase Inhibitors; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Vascular Stiffness; Vasoconstriction | 2014 |
A novel continuous flow biosynthesis of caffeic acid phenethyl ester from alkyl caffeate and phenethanol in a packed bed microreactor.
Topics: Bioreactors; Caffeic Acids; Chromatography, High Pressure Liquid; Ethanol; Kinetics; Phenylethyl Alcohol; Proton Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization | 2014 |
Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage.
Topics: Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Caffeic Acids; Cyclin D1; Diet, High-Fat; Down-Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mitosis; Obesity; Phenylethyl Alcohol; Propolis | 2014 |
Caffeic acid phenethyl ester (CAPE): scavenger of peroxynitrite in vitro and in sepsis models.
Topics: Animals; Caffeic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Free Radical Scavengers; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice, Inbred BALB C; Nitric Oxide; Peroxynitrous Acid; Phenylethyl Alcohol; Sepsis; Tyrosine | 2014 |
Synthesis of caffeic acid phenethyl ester derivatives, and their cytoprotective and neuritogenic activities in PC12 cells.
Topics: Animals; Caffeic Acids; Hydrogen Peroxide; Molecular Structure; Neurites; PC12 Cells; Phenylethyl Alcohol; Protective Agents; Rats; Structure-Activity Relationship | 2014 |
Effects of intrathecal caffeic acid phenethyl ester and methylprednisolone on oxidant/antioxidant status in traumatic spinal cord injuries.
Topics: Animals; Antioxidants; Caffeic Acids; Female; Injections, Spinal; Lipid Peroxidation; Methylprednisolone; Phenylethyl Alcohol; Rats; Rats, Wistar; Spinal Cord Injuries | 2015 |
Protective effects of caffeic acid phenethyl ester (CAPE) against neomycin-induced hair cell damage in zebrafish.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Caffeic Acids; Hair Cells, Auditory; Microscopy, Electron, Scanning; Mitochondria; Models, Animal; Neomycin; Phenylethyl Alcohol; Zebrafish | 2014 |
The effects of melatonin and caffeic acid phenethyl ester (CAPE) on fracture healing under ischemic conditions.
Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Fracture Fixation, Intramedullary; Fracture Healing; Ischemia; Male; Melatonin; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Tibial Fractures | 2014 |
Caffeic acid phenethyl ester promotes anti-inflammatory effects by inhibiting MAPK and NF-κB signaling in activated HMC-1 human mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Calcium; Cell Survival; Cells, Cultured; Cytokines; Histamine; Histamine Release; Humans; Hypersensitivity; Immunoglobulin E; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mast Cells; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Phenylethyl Alcohol; Phosphorylation | 2014 |
Ganglioside GM3 is required for caffeic acid phenethyl ester-induced megakaryocytic differentiation of human chronic myelogenous leukemia K562 cells.
Topics: Antioxidants; Caffeic Acids; Cell Differentiation; Cell Proliferation; G(M3) Ganglioside; Humans; K562 Cells; Megakaryocytes; Phenylethyl Alcohol | 2014 |
Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways.
Topics: Antineoplastic Agents; Caffeic Acids; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; HCT116 Cells; Humans; MAP Kinase Signaling System; Phenylethyl Alcohol | 2014 |
Caffeic acid phenethylester increases stress resistance and enhances lifespan in Caenorhabditis elegans by modulation of the insulin-like DAF-16 signalling pathway.
Topics: Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caffeic Acids; DNA-Binding Proteins; Forkhead Transcription Factors; HCT116 Cells; Humans; Insulin; Longevity; Phenylethyl Alcohol; Signal Transduction; Stress, Physiological; Temperature; Transcription Factors | 2014 |
Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester-induced apoptosis in C6 glioma cells.
Topics: Animals; Apoptosis; Caffeic Acids; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Glioma; MAP Kinase Signaling System; Neoplasm Proteins; Phenylethyl Alcohol; Rats; Receptor, Nerve Growth Factor; Sphingomyelin Phosphodiesterase | 2014 |
Nrf2-mediated HO-1 induction coupled with the ERK signaling pathway contributes to indirect antioxidant capacity of caffeic acid phenethyl ester in HepG2 cells.
Topics: Antioxidants; Caffeic Acids; Heme Oxygenase-1; Hep G2 Cells; Humans; MAP Kinase Signaling System; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol | 2014 |
Caffeic acid phenethyl ester protects against amphotericin B induced nephrotoxicity in rat model.
Topics: Amphotericin B; Animals; Anti-Bacterial Agents; Caffeic Acids; Catalase; Kidney Diseases; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Rats; Superoxide Dismutase | 2014 |
The effect of caffeic acid phenethyl ester on isoproterenol-induced myocardial injury in hypertensive rats.
Topics: Animals; Antioxidants; Blood Pressure; Caffeic Acids; Disease Models, Animal; Hypertension; Injections, Intraperitoneal; Isoproterenol; Lipid Peroxidation; Myocardial Infarction; Phenylethyl Alcohol; Rats | 2014 |
Caffeic acid phenethyl ester inhibits the inflammatory effects of interleukin-1β in human corneal fibroblasts.
Topics: Adult; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Cell Adhesion Molecules; Cell Migration Assays, Leukocyte; Cell Movement; Chemokines; Cornea; Cytokines; Fibroblasts; HL-60 Cells; Humans; Interleukin-1beta; Middle Aged; Phenylethyl Alcohol; Signal Transduction | 2014 |
A CAPE analogue as novel antiplatelet agent efficiently inhibits collagen-induced platelet aggregation.
Topics: Animals; Blood Platelets; Caffeic Acids; Collagen; Cyclic AMP; Cyclooxygenase 1; In Vitro Techniques; Indicators and Reagents; Male; Nitric Oxide; Phenylethyl Alcohol; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Serotonin; Thromboxane B2 | 2014 |
Identification of differential proteins in colorectal cancer cells treated with caffeic acid phenethyl ester.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Electrophoresis, Gel, Two-Dimensional; Fluorescent Antibody Technique; Humans; Microscopy, Confocal; Neoplasm Proteins; Phenylethyl Alcohol; Proteomics; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
PI3K/Akt regulates survival during differentiation of human macrophages by maintaining NF-κB-dependent expression of antiapoptotic Bcl-xL.
Topics: Anthracenes; Apoptosis; bcl-X Protein; Caffeic Acids; Cell Line, Tumor; Chromones; Flavonoids; Gene Expression Regulation, Developmental; Hematopoiesis; Humans; Macrophage Colony-Stimulating Factor; Macrophages; MAP Kinase Signaling System; Monocytes; Morpholines; NF-kappa B; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Sesquiterpenes; Signal Transduction; Tetradecanoylphorbol Acetate | 2014 |
Inhibitory activities of propolis and its promising component, caffeic acid phenethyl ester, against amyloidogenesis of human transthyretin.
Topics: Amyloid Neuropathies, Familial; Amyloidosis; Caffeic Acids; Coumaric Acids; Masoprocol; Phenylethyl Alcohol; Prealbumin; Propolis | 2014 |
Assesment the role of oxidative stress and efficacy of caffeic acid phenethyl ester (CAPE) on neurotoxicity induced by isoniazid and ethambutol in a rat model.
Topics: Animals; Antioxidants; Brain; Caffeic Acids; Ethambutol; Isoniazid; Male; Models, Animal; Neurotoxicity Syndromes; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Superoxide Dismutase; Treatment Outcome | 2014 |
Effects of caffeic acid phenethyl ester on palatal mucosal defects and tooth extraction sockets.
Topics: Animals; Caffeic Acids; Male; Mouth Mucosa; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Tooth Extraction; Tooth Socket; Wound Healing | 2014 |
Effects of caffeic acid phenethyl ester on wound healing in calvarial defects.
Topics: Administration, Topical; Animals; Antioxidants; Bone Diseases; Bone Regeneration; Caffeic Acids; Connective Tissue; Image Processing, Computer-Assisted; Injections, Intraperitoneal; Male; NF-kappa B; Osteogenesis; Parietal Bone; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Wound Healing | 2015 |
DFT study of the effect of solvent on the H-atom transfer involved in the scavenging of the free radicals (·)HO2 and (·)O2(-) by caffeic acid phenethyl ester and some of its derivatives.
Topics: Benzoates; Caffeic Acids; Computer Simulation; Coumaric Acids; Electrons; Energy Transfer; Free Radical Scavengers; Hydrogen; Kinetics; Models, Chemical; Models, Molecular; Peroxides; Phenylethyl Alcohol; Protons; Solvents; Superoxides; Temperature | 2014 |
The radio-protective effects of caffeic acid phenethyl ester and thymoquinone in rats exposed to total head irradiation.
Topics: Animals; Benzoquinones; Caffeic Acids; Head; Liver; Liver Diseases; Phenylethyl Alcohol; Radiation Dosage; Radiation Exposure; Radiation Injuries; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Treatment Outcome | 2015 |
Preparation of caffeic acid phenethyl ester-incorporated nanoparticles and their biological activity.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Caffeic Acids; Carcinoma; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Drug Carriers; Drug Compounding; Lung; Lung Neoplasms; Macrophages; Mice; Mice, Inbred BALB C; Micelles; Nanoparticles; Neoplasm Transplantation; Phenylethyl Alcohol; Solubility; Tumor Burden | 2015 |
Anti-catabolic effect of caffeic acid phenethyl ester, an active component of honeybee propolis on bone loss in ovariectomized mice: a micro-computed tomography study and histological analysis.
Topics: Animals; Bone Density; Caffeic Acids; Female; Metabolism; Mice; Mice, Inbred C57BL; Ovariectomy; Phenylethyl Alcohol; Propolis; Tomography, X-Ray Computed | 2014 |
CD133⁺ melanoma subpopulation acquired resistance to caffeic acid phenethyl ester-induced apoptosis is attributed to the elevated expression of ABCB5: significance for melanoma treatment.
Topics: AC133 Antigen; Antigens, CD; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeic Acids; Cell Line, Tumor; Drug Resistance, Neoplasm; Glycoproteins; Humans; Melanoma; Peptides; Phenylethyl Alcohol; Signal Transduction | 2015 |
Caffeic acid phenethyl ester (CAPE) protects PC12 cells from MPP+ toxicity by inducing the expression of neuron-typical proteins.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Caffeic Acids; Cell Death; Cell Differentiation; Dose-Response Relationship, Drug; GAP-43 Protein; Nerve Growth Factor; Neurites; Neuroprotective Agents; PC12 Cells; Phenylethyl Alcohol; Rats; Synapsins; Synaptophysin | 2014 |
Suppression of skin inflammation in keratinocytes and acute/chronic disease models by caffeic acid phenethyl ester.
Topics: Acute Disease; Animals; Caffeic Acids; Cell Line; Chronic Disease; Cyclooxygenase 2; Dermatitis, Atopic; Disease Models, Animal; Humans; Immunoglobulin E; Inflammation; Keratinocytes; Mice; Mice, Inbred Strains; NF-kappa B; Oxazolone; Phenylethyl Alcohol; Propolis; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Water Loss, Insensible | 2015 |
Protective role of caffeic acid phenethyl ester on serum cholinesterase inhibition by acute exposure to diazinon in rats.
Topics: Animals; Caffeic Acids; Cholinesterase Inhibitors; Cholinesterases; Diazinon; Insecticides; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Thermodynamics | 2014 |
Effect of caffeic acid phenethyl ester on Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages.
Topics: Animals; Caffeic Acids; Cytokines; Gene Expression Profiling; Immunologic Factors; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Phenylethyl Alcohol; Prevotella intermedia; Real-Time Polymerase Chain Reaction | 2015 |
Fibrinolytic activity and dose-dependent effect of incubating human blood clots in caffeic acid phenethyl ester: in vitro assays.
Topics: Caffeic Acids; Fibrinolysis; Humans; Microscopy, Confocal; Phenylethyl Alcohol; Thrombelastography; Thrombosis | 2015 |
Protective effects of caffeic acid phenethyl ester against acute radiation-induced hepatic injury in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeic Acids; Glutathione; Liver; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Protective Agents; Radiation Injuries, Experimental; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha; X-Rays | 2015 |
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeic Acids; Eye Diseases; Indomethacin; Inflammation; Male; Phenylethyl Alcohol; Rabbits | 2015 |
Caffeic acid phenethyl ester reduces the secretion of vascular endothelial growth factor through the inhibition of the ROS, PI3K and HIF-1α signaling pathways in human retinal pigment epithelial cells under hypoxic conditions.
Topics: Caffeic Acids; Cell Line; Cell Survival; Epithelial Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Retinal Pigment Epithelium; Vascular Endothelial Growth Factor A | 2015 |
Regulatory effects of caffeic acid phenethyl ester on neuroinflammation in microglial cells.
Topics: AMP-Activated Protein Kinases; Animals; Caffeic Acids; Cell Line; Cyclooxygenase 2; Erythropoietin; Heme Oxygenase-1; Inflammation; Male; Mice; Mice, Inbred ICR; Microglia; Nitric Oxide Synthase Type II; Phenylethyl Alcohol | 2015 |
Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Drug Synergism; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prostatic Neoplasms, Castration-Resistant; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; RNA Interference; S-Phase Kinase-Associated Proteins; Signal Transduction; Time Factors; Transfection; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2015 |
An in vitro and in vivo investigation of the cytotoxic effects of caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester and bortezomib in multiple myeloma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Interleukin-6; Mice; Mice, Inbred BALB C; Multiple Myeloma; NF-kappa B; Phenylethyl Alcohol; Pyrazines; Survival Analysis | 2015 |
Caffeic acid phenethyl ester lessens disease symptoms in an experimental autoimmune uveoretinitis mouse model.
Topics: Animals; Autoimmune Diseases; Blotting, Western; Caffeic Acids; Disease Models, Animal; Eye Proteins; Flow Cytometry; Immunoglobulin G; Interferon-gamma; Interleukin-6; Lymphocyte Activation; Mice; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Retinitis; Retinol-Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Tumor Necrosis Factor-alpha; Uveitis | 2015 |
Synthesis, antitumor activity, and mechanism of action of 6-acrylic phenethyl ester-2-pyranone derivatives.
Topics: Actins; Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Movement; Cytoskeleton; Esters; HeLa Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Microscopy, Fluorescence; Neoplasm Invasiveness; Phenylethyl Alcohol; Pyrones; Solubility; Structure-Activity Relationship | 2015 |
Caffeic acid phenethyl ester abrogates bone resorption in a murine calvarial model of polyethylene particle-induced osteolysis.
Topics: Animals; Bone Resorption; Caffeic Acids; Disease Models, Animal; Female; Mice; Osteolysis; Phenylethyl Alcohol; Polyethylene; Skull; X-Ray Microtomography | 2015 |
Caffeic acid phenethyl ester inhibits liver fibrosis in rats.
Topics: Alcohol Drinking; Animals; Antioxidants; Biomarkers; Caffeic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Diet, High-Fat; Dose-Response Relationship, Drug; Hepatic Stellate Cells; Liver; Liver Cirrhosis, Experimental; Male; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol; Rats, Sprague-Dawley | 2015 |
The effects of Nigella sativa oil, thymoquinone, propolis, and caffeic acid phenethyl ester on radiation-induced cataract.
Topics: Animals; Antioxidants; Benzoquinones; Caffeic Acids; Cataract; Cranial Irradiation; Dose-Response Relationship, Drug; Male; Phenylethyl Alcohol; Plant Oils; Propolis; Radiation Injuries; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2016 |
The effects of caffeic acid phenethyl ester on inflammatory cytokines after acute spinal cord injury.
Topics: Animals; Caffeic Acids; Cytokines; Interleukin-1beta; Male; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Wistar; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2015 |
Inhibitory effects of hydroxylated cinnamoyl esters on lipid absorption and accumulation.
Topics: 3T3-L1 Cells; Animals; Anti-Obesity Agents; Caffeic Acids; Catechols; Cell Differentiation; Corn Oil; Dose-Response Relationship, Drug; Intestinal Absorption; Lipase; Mice; Obesity; Pancreas; Phenylethyl Alcohol; Structure-Activity Relationship; Swine; Triglycerides | 2015 |
Value of caffeic acid phenethyl ester pretreatment in experimental sepsis model in rats.
Topics: Animals; Caffeic Acids; Disease Models, Animal; Endothelin-1; Inflammation; Male; Malondialdehyde; Oxidative Stress; Oxygen; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Sepsis; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2015 |
The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of d-galactosamine-induced acute hepatitis in rats.
Topics: Animals; Caffeic Acids; Caspase 3; Chemical and Drug Induced Liver Injury; Galactosamine; Glycogen; Ki-67 Antigen; Liver; Male; Malondialdehyde; Mast Cells; Pentoxifylline; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar | 2016 |
Caffeic Acid phenethyl ester and ethanol extract of propolis induce the complementary cytotoxic effect on triple-negative breast cancer cell lines.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caffeic Acids; Cell Line, Tumor; Female; Humans; Phenylethyl Alcohol; Phytotherapy; Propolis; Triple Negative Breast Neoplasms | 2015 |
Sonoran propolis and some of its chemical constituents inhibit in vitro growth of Giardia lamblia trophozoites.
Topics: Animals; Caffeic Acids; Cell Proliferation; Flavonoids; Giardia lamblia; Mexico; Phenylethyl Alcohol; Propolis; Rutin; Trophozoites | 2015 |
The effects of caffeic acid phenethyl ester (CAPE) on bacterial translocation and inflammatory response in an experimental intestinal obstruction model in rats.
Topics: Animals; Anti-Inflammatory Agents; Bacterial Translocation; Caffeic Acids; Disease Models, Animal; Inflammation Mediators; Injections, Intraperitoneal; Intestinal Mucosa; Intestinal Obstruction; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar | 2015 |
In vitro effect of caffeic acid phenethyl ester on matrix metalloproteinases (MMP-1 and MMP-9) and their inhibitor (TIMP-1) in lipopolysaccharide-activated human monocytes.
Topics: Caffeic Acids; Cell Line; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Lipopolysaccharides; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Monocytes; Phenylethyl Alcohol; Real-Time Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinase-1 | 2015 |
Caffeic acid phenethyl ester attenuates ionize radiation-induced intestinal injury through modulation of oxidative stress, apoptosis and p38MAPK in rats.
Topics: Animals; Apoptosis; Caffeic Acids; Intestinal Mucosa; Intestines; Male; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Radiation, Ionizing; Rats; Rats, Sprague-Dawley | 2015 |
CAPE Analogs Induce Growth Arrest and Apoptosis in Breast Cancer Cells.
Topics: Apoptosis; Biphenyl Compounds; Caffeic Acids; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Female; Free Radicals; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Inhibitory Concentration 50; Luciferases; MCF-7 Cells; Mutation; Phenylethyl Alcohol; Picrates; Signal Transduction; Structure-Activity Relationship; Tumor Suppressor Protein p53 | 2015 |
Dengue Virus Infection Causes the Activation of Distinct NF-κB Pathways for Inducible Nitric Oxide Synthase and TNF-α Expression in RAW264.7 Cells.
Topics: Animals; Caffeic Acids; Cell Line; Dengue Virus; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Signal Transduction; Tumor Necrosis Factor-alpha | 2015 |
Protective Effects of Caffeic Acid Phenethyl Ester on Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Caffeic Acids; Catalase; Cyclophosphamide; Cystitis; Hemorrhage; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase; Urinary Bladder | 2015 |
Caffeic acid phenethyl ester protects lung alveolar epithelial cells from cigarette smoke-induced damage.
Topics: Antioxidants; Caffeic Acids; Cell Death; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cytokines; Epithelial Cells; Humans; Inflammation; Lipid Peroxidation; Lung; Nicotiana; Oxidative Stress; Phenylethyl Alcohol; Pulmonary Alveoli; Real-Time Polymerase Chain Reaction; Respiratory Mucosa; RNA; Smoking | 2015 |
Caffeic acid phenethyl ester inhibits 3-MC-induced CYP1A1 expression through induction of hypoxia-inducible factor-1α.
Topics: Animals; Apoptosis; Caffeic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Hypoxia-Inducible Factor 1, alpha Subunit; Methylcholanthrene; Mice; Phenylethyl Alcohol | 2015 |
Combination of immunoprecipitation (IP)-ATP_Glo kinase assay and melanogenesis for the assessment of potent and safe PAK1-blockers in cell culture.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Humans; Immunoprecipitation; Melanins; Mice; p21-Activated Kinases; Phenylethyl Alcohol; Protein Kinase Inhibitors; Reagent Kits, Diagnostic; Triterpenes | 2015 |
Inhibition of Survival Pathways MAPK and NF-kB Triggers Apoptosis in Pancreatic Ductal Adenocarcinoma Cells via Suppression of Autophagy.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Butadienes; Caffeic Acids; Carcinoma, Pancreatic Ductal; Cell Growth Processes; Cell Line, Tumor; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Nitriles; Pancreatic Neoplasms; Phenylethyl Alcohol; Protein Kinase Inhibitors; Survival Rate | 2016 |
Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats.
Topics: Animals; Caffeic Acids; Cystathionine gamma-Lyase; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Hydrogen Sulfide; Immunohistochemistry; Liver; Liver Cirrhosis; Male; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2015 |
Anti-Apoptotic and Anti-Oxidant Effects of Caffeic Acid Phenethyl Ester on Cadmium-Induced Testicular Toxicity in Rats.
Topics: Animals; Antioxidants; Apoptosis; Cadmium; Caffeic Acids; Male; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Testis | 2016 |
The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis.
Topics: Actins; Adult; Caffeic Acids; Cell Nucleus; Collagen Type I; Fibroblasts; Fibronectins; Fibrosis; Gene Expression Regulation; Humans; Microfilament Proteins; Muscle Proteins; Myofibroblasts; Phenylethyl Alcohol; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Protein Transport; RNA, Messenger; Smad Proteins; Tenascin; Transcription Factors; Transforming Growth Factor beta1; Young Adult | 2016 |
The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Caffeic Acids; Carbonic Anhydrases; Glutathione Transferase; Isoenzymes; Lactoperoxidase; Phenylethyl Alcohol | 2016 |
Effects of Caffeic Acid Phenethyl Ester and 4-Vinylcatechol on the Stabilities of Oil-in-Water Emulsions of Stripped Soybean Oil.
Topics: Antioxidants; Caffeic Acids; Catechols; Emulsions; Molecular Structure; Oxidation-Reduction; Phenylethyl Alcohol; Soybean Oil | 2015 |
Effects of caffeic acid phenethyl ester on matrix molecules and angiogenetic and anti-angiogenetic factors in gastric cancer cells cultured on different substrates.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Phenylethyl Alcohol; Stomach Neoplasms | 2016 |
Anti-Neoplastic and Calcium Modulatory Action of Caffeic Acid Phenethyl Ester and Dasatinib in C6 Glial Cells: A Therapeutic Perspective.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Calcium; Cell Death; Cell Line, Tumor; Dasatinib; Glioma; Neuroglia; Phenylethyl Alcohol; Rats | 2016 |
Comparative evaluation of antibacterial activity of caffeic acid phenethyl ester and PLGA nanoparticle formulation by different methods.
Topics: Anti-Bacterial Agents; Caffeic Acids; Capsules; Chemistry, Pharmaceutical; Drug Delivery Systems; Escherichia coli; Lactic Acid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nanoparticles; Particle Size; Phenylethyl Alcohol; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Staphylococcus aureus | 2016 |
Antioxidant Properties of Caffeic acid Phenethyl Ester and 4-Vinylcatechol in Stripped Soybean Oil.
Topics: alpha-Tocopherol; Antioxidants; Caffeic Acids; Catechols; Hydrogen Peroxide; Oxidation-Reduction; Peroxides; Phenylethyl Alcohol; Soybean Oil | 2016 |
The role of CAPE in PI3K/AKT/mTOR activation and oxidative stress on testis torsion.
Topics: Animals; Antioxidants; Caffeic Acids; Drug Evaluation, Preclinical; Male; Oxidative Stress; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Spermatic Cord Torsion; Testis; TOR Serine-Threonine Kinases | 2016 |
Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Beclin-1; Breast Neoplasms; Caffeic Acids; Female; Humans; MCF-7 Cells; Membrane Proteins; Microtubule-Associated Proteins; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2; Tamoxifen | 2016 |
Caffeic acid phenethyl ester: Inhibition of metastatic cell behaviours via voltage-gated sodium channel in human breast cancer in vitro.
Topics: Antineoplastic Agents; Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Electrophysiological Phenomena; Humans; Neoplasm Metastasis; Phenylethyl Alcohol; Voltage-Gated Sodium Channels | 2016 |
Effect of caffeic acid phenethyl ester on bone formation in the expanded inter-premaxillary suture.
Topics: Animals; Caffeic Acids; Injections, Intraperitoneal; Male; Osteogenesis; Palatal Expansion Technique; Palate, Hard; Phenylethyl Alcohol; Rats, Sprague-Dawley; Time Factors | 2015 |
The Effect of Caffeic Acid Phenethyl Ester (CAPE) Fortification on the Liver Element Distribution that Occurs After Exercise.
Topics: Animals; Cadmium; Caffeic Acids; Calcium; Chromium; Copper; Injections, Intraperitoneal; Iron; Liver; Magnesium; Male; Phenylethyl Alcohol; Physical Conditioning, Animal; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Tissue Distribution; Zinc | 2016 |
Caffeic acid phenethyl ester exhibiting distinctive binding interaction with human serum albumin implies the pharmacokinetic basis of propolis bioactive components.
Topics: Caffeic Acids; Circular Dichroism; Fluorescence Resonance Energy Transfer; Humans; Hydrogen Bonding; Molecular Docking Simulation; Phenylethyl Alcohol; Propolis; Protein Binding; Protein Structure, Secondary; Serum Albumin; Spectrometry, Fluorescence; Thermodynamics | 2016 |
Caffeic acid phenethyl ester activates pro-apoptotic and epithelial-mesenchymal transition-related genes in ovarian cancer cells A2780 and A2780cis.
Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Ovarian Neoplasms; Phenylethyl Alcohol | 2016 |
The Protective Effects of Caffeic Acid Phenethyl Ester on Acetylsalicylic Acid-induced Lung Injury in Rats.
Topics: Animals; Aspirin; Caffeic Acids; Drug Evaluation, Preclinical; Female; Lung; Lung Injury; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats, Wistar | 2016 |
Activation of NF-κB and AP-1 Mediates Hyperproliferation by Inducing β-Catenin and c-Myc in Helicobacter pylori-Infected Gastric Epithelial Cells.
Topics: beta Catenin; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; DNA, Bacterial; Epithelial Cells; Gastric Mucosa; Gastritis; Gene Expression Regulation, Bacterial; Helicobacter Infections; Helicobacter pylori; Humans; NF-kappa B; Peptide Fragments; Phenylethyl Alcohol; Proto-Oncogene Proteins c-jun; Repressor Proteins; Transcription Factor AP-1; Transcription Factors | 2016 |
Could Caffeic Acid Phenethyl Ester Expand the Antitumor Effect of Tamoxifen in Breast Carcinoma?
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Caffeic Acids; Carcinoma, Ehrlich Tumor; Caspase 3; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Phenylethyl Alcohol; Proteins; Tamoxifen; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2016 |
Effect of Caffeic Acid Phenethyl Ester on Vascular Damage Caused by Consumption of High Fructose Corn Syrup in Rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Caffeic Acids; High Fructose Corn Syrup; In Vitro Techniques; Nitric Oxide Synthase Type III; Phenylephrine; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Vascular Diseases; Vascular Resistance; Vasodilation | 2016 |
Effect of caffeic acid phenethyl ester on oxidant and anti-oxidant status of liver and serum in a rat model with acute methanol intoxication.
Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Ethanol; Liver; Male; Methanol; Methotrexate; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2017 |
Protective Effects of Caffeic Acid Phenethyl Ester on Fluoxetine-Induced Hepatotoxicity: An Experimental Study.
Topics: Animals; Antioxidants; Aryldialkylphosphatase; Caffeic Acids; Chemical and Drug Induced Liver Injury; Fluoxetine; Male; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2016 |
In vitro CAPE inhibitory activity towards human AKR1C3 and the molecular basis.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Binding Sites; Caffeic Acids; Crystallography, X-Ray; Humans; Hydroxybenzoates; Hydroxyprostaglandin Dehydrogenases; Male; Phenylethyl Alcohol; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Protein Structure, Tertiary | 2016 |
Effects of Oxidative Stress and Testosterone on Pro-Inflammatory Signaling in a Female Rat Dopaminergic Neuronal Cell Line.
Topics: Animals; Apoptosis; Caffeic Acids; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dopaminergic Neurons; Female; Ibuprofen; Inflammation; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Signal Transduction; Testosterone | 2016 |
CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling.
Topics: Animals; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Phenylethyl Alcohol; Prostatic Neoplasms; Transfection; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2016 |
The effects of caffeic acid phenethyl ester on streptozotocin-induced diabetic liver injury.
Topics: Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Glutathione; Liver; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2016 |
Caffeic acid phenethyl ester enhances TRAIL-mediated apoptosis via CHOP-induced death receptor 5 upregulation in hepatocarcinoma Hep3B cells.
Topics: Apoptosis; Caffeic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Neoplasm Proteins; Phenylethyl Alcohol; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor CHOP; Up-Regulation | 2016 |
Protective Effects of Intralipid and Caffeic Acid Phenethyl Ester (CAPE) on Hepatotoxicity and Pancreatic Injury Caused by Dichlorvos in Rats.
Topics: Animals; Caffeic Acids; Chemical and Drug Induced Liver Injury; Dichlorvos; Emulsions; Gene Expression Regulation; Male; Oxidative Stress; Pancreatic Diseases; Phenylethyl Alcohol; Phospholipids; Rats; Rats, Wistar; Soybean Oil; Treatment Outcome | 2016 |
Neuroprotective effects of caffeic acid phenethyl ester against sevoflurane‑induced neuronal degeneration in the hippocampus of neonatal rats involve MAPK and PI3K/Akt signaling pathways.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Caffeic Acids; Female; Hippocampus; MAP Kinase Signaling System; Methyl Ethers; Neurodegenerative Diseases; Neuroprotective Agents; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Sevoflurane; Signal Transduction | 2016 |
Fabrication of Novel Bioactive Cellulose-Based Films Derived from Caffeic Acid Phenethyl Ester-Loaded Nanoparticles via a Rapid Expansion Process: RESOLV.
Topics: Anti-Infective Agents; Antioxidants; Bacteria; Caffeic Acids; Cellulose; Food Packaging; Microbial Sensitivity Tests; Nanoparticles; Particle Size; Phenylethyl Alcohol; Yeasts | 2016 |
Protective Effects of Intralipid and Caffeic Acid Phenyl Esther (CAPE) on Neurotoxicity Induced by Ethanol in Rats.
Topics: Animals; Antioxidants; Brain; Caffeic Acids; Cerebellum; Emulsions; Ethanol; Male; Neuroprotective Agents; Oxidative Stress; Phenylethyl Alcohol; Phospholipids; Rats; Soybean Oil | 2017 |
Structure-activity relationship of caffeic acid phenethyl ester analogs as new 5-lipoxygenase inhibitors.
Topics: Caffeic Acids; Carbon-13 Magnetic Resonance Spectroscopy; Free Radical Scavengers; HEK293 Cells; Humans; Lipoxygenase Inhibitors; Mass Spectrometry; Molecular Docking Simulation; Neutrophils; Phenylethyl Alcohol; Proton Magnetic Resonance Spectroscopy; Structure-Activity Relationship; Thapsigargin | 2017 |
Caffeic acid phenethyl ester alleviates asthma by regulating the airway microenvironment via the ROS-responsive MAPK/Akt pathway.
Topics: Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Caffeic Acids; Chemokine CCL11; Chemokine CCL2; Female; Gene Expression Regulation; Humans; Immunoglobulin E; Intercellular Adhesion Molecule-1; Interleukin-13; Interleukin-4; Lung; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Ovalbumin; Phenylethyl Alcohol; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2016 |
Role of CAPE on cardiomyocyte protection via connexin 43 regulation under hypoxia.
Topics: Caffeic Acids; Cell Line; Connexin 43; Humans; Hypoxia; L-Lactate Dehydrogenase; Mitochondria, Heart; Myocardial Ischemia; Myocytes, Cardiac; Phenylethyl Alcohol | 2016 |
Caffeic acid phenethyl ester attenuates lipopolysaccharide-stimulated proinflammatory responses in human gingival fibroblasts via NF-κB and PI3K/Akt signaling pathway.
Topics: Active Transport, Cell Nucleus; Anti-Inflammatory Agents; Caffeic Acids; Cell Nucleus; Enzyme Activation; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Inflammation; Inflammation Mediators; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Myeloid Differentiation Factor 88; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Toll-Like Receptor 4; Transcription Factor RelA | 2017 |
Caffeic acid phenethyl ester (CAPE) revisited: Covalent modulation of XPO1/CRM1 activities and implication for its mechanism of action.
Topics: Binding Sites; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Exportin 1 Protein; HeLa Cells; Humans; Karyopherins; Mass Spectrometry; MCF-7 Cells; Microscopy, Confocal; Molecular Dynamics Simulation; Peptides; Phenylethyl Alcohol; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship | 2017 |
Targeting ASC in NLRP3 inflammasome by caffeic acid phenethyl ester: a novel strategy to treat acute gout.
Topics: Administration, Oral; Animals; Biomarkers; Caffeic Acids; CARD Signaling Adaptor Proteins; Disease Models, Animal; Gout; Inflammasomes; Liquid Crystals; Macrophages; Mice; Models, Molecular; Molecular Conformation; NLR Family, Pyrin Domain-Containing 3 Protein; Phenylethyl Alcohol; Protein Binding; Uric Acid | 2016 |
Bone resorption, matrix metalloproteinases and caffeic acid phenethyl ester.
Topics: Biomarkers; Bone Resorption; Caffeic Acids; Humans; Matrix Metalloproteinases; Osteoporosis; Phenylethyl Alcohol | 2016 |
Attenuating effects of caffeic acid phenethyl ester with intralipid on hepatotoxicity of chlorpyrifos in the case of rats.
Topics: Animals; Antioxidants; Caffeic Acids; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Immunochemistry; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2016 |
Mixed effects of caffeic acid phenethyl ester (CAPE) on joint inflammation, bone loss and gastrointestinal inflammation in a murine model of collagen antibody-induced arthritis.
Topics: Animals; Arthritis, Experimental; Bone Resorption; Caffeic Acids; Collagen; Gastrointestinal Tract; Inflammation; Joints; Mice; Mice, Inbred BALB C; Phenylethyl Alcohol; Random Allocation; Tomography, X-Ray Computed; Treatment Outcome | 2017 |
HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis.
Topics: Adult; Astrocytes; Caffeic Acids; Complement C3; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Female; Fetus; Gene Expression Regulation; Gene Expression Regulation, Viral; Glial Fibrillary Acidic Protein; HIV Infections; Humans; Interleukin-6; Male; Middle Aged; NF-kappa B; Phenylethyl Alcohol; Promoter Regions, Genetic; Signal Transduction | 2017 |
The effects of pollen, propolis, and caffeic acid phenethyl ester on tyrosine hydroxylase activity and total RNA levels in hypertensive rats caused by nitric oxide synthase inhibition: experimental, docking and molecular dynamic studies.
Topics: Adrenal Medulla; Animals; Caffeic Acids; Catalytic Domain; Catecholamines; Disease Models, Animal; Heart; Humans; Hypertension; Hypothalamus; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylethyl Alcohol; Pollen; Propolis; Rats; Tyrosine 3-Monooxygenase | 2018 |
Relevance of mortalin to cancer cell stemness and cancer therapy.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Caffeic Acids; Cell Line; Cell Line, Tumor; HSP70 Heat-Shock Proteins; Humans; Neoplasms; Neoplastic Stem Cells; Phenylethyl Alcohol; Pyridines; RNA, Small Interfering; Thiazoles; Up-Regulation | 2017 |
Caffeic acid phenethyl ester upregulates N-myc downstream regulated gene 1 via ERK pathway to inhibit human oral cancer cell growth in vitro and in vivo.
Topics: Animals; Caffeic Acids; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mouth Neoplasms; Phenylethyl Alcohol; Promoter Regions, Genetic; Squamous Cell Carcinoma of Head and Neck; Up-Regulation; Xenograft Model Antitumor Assays | 2017 |
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-1.
Topics: Animals; Antioxidants; Caffeic Acids; Cell Survival; Cells, Cultured; Enzyme Induction; Heme Oxygenase-1; Humans; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2017 |
Caffeic acid phenethyl ester attenuates liver fibrosis via inhibition of TGF-β1/Smad3 pathway and induction of autophagy pathway.
Topics: Actins; Animals; Autophagosomes; Autophagy; Blotting, Western; Caffeic Acids; Carbon Tetrachloride; Cell Line; Collagen Type I; Dose-Response Relationship, Drug; Gene Expression; Hepatic Stellate Cells; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Phenylethyl Alcohol; Phosphorylation; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad3 Protein; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2017 |
An Intestinal Farnesoid X Receptor-Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice.
Topics: Acetyl Coenzyme A; Amidohydrolases; Animals; Body Weight; Caffeic Acids; Ceramides; Diet, High-Fat; Gastrointestinal Microbiome; Gluconeogenesis; Ileum; Insulin; Intestinal Mucosa; Intestines; Isoxazoles; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Phenylethyl Alcohol; Pyruvate Carboxylase; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Taurocholic Acid | 2017 |
NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting "stemness".
Topics: Antineoplastic Agents; Ascorbic Acid; Biomarkers, Tumor; Caffeic Acids; Cell Proliferation; Dioxolanes; Flow Cytometry; Humans; MCF-7 Cells; NAD; Neoplastic Stem Cells; Optical Imaging; Phenylethyl Alcohol | 2017 |
Caffeic acid phenethyl ester up-regulates antioxidant levels in hepatic stellate cell line T6
Topics: Animals; Antioxidants; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Hepatic Stellate Cells; Immunoenzyme Techniques; MAP Kinase Signaling System; Microscopy, Fluorescence; NF-E2-Related Factor 2; Oxidative Stress; Phenol; Phenylethyl Alcohol; Protein Transport; Rats; Reactive Oxygen Species | 2017 |
Direct interaction between caffeic acid phenethyl ester and human neutrophil elastase inhibits the growth and migration of PANC-1 cells.
Topics: alpha 1-Antitrypsin; Caffeic Acids; Carcinoma, Pancreatic Ductal; Catalytic Domain; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Leukocyte Elastase; Models, Molecular; Molecular Dynamics Simulation; Pancreatic Neoplasms; Phenylethyl Alcohol | 2017 |
Caffeic acid phenethyl ester protects against glucocorticoid-induced osteoporosis in vivo: Impact on oxidative stress and RANKL/OPG signals.
Topics: Animals; Caffeic Acids; Glucocorticoids; Male; Osteoporosis; Osteoprotegerin; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; RANK Ligand; Rats; Rats, Sprague-Dawley | 2017 |
The effect of caffeic acid phenethyl ester and thymoquinone on otitis media with effusion in rats.
Topics: Animals; Anti-Inflammatory Agents; Benzoquinones; Caffeic Acids; Disease Models, Animal; Eustachian Tube; Injections, Intraperitoneal; Male; Otitis Media with Effusion; Phenylethyl Alcohol; Rats; Rats, Wistar; Temporal Bone | 2017 |
Neuroprotective effect of three caffeic acid derivatives via ameliorate oxidative stress and enhance PKA/CREB signaling pathway.
Topics: Animals; Avoidance Learning; Caffeic Acids; Cell Survival; Curcumin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Galactose; Hydrogen Peroxide; Lactates; Maze Learning; Mice; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Phenylethyl Alcohol; Random Allocation; Rats; Signal Transduction; Spatial Memory | 2017 |
Caffeic acid phenethyl ester attenuates pathological cardiac hypertrophy by regulation of MEK/ERK signaling pathway in vivo and vitro.
Topics: Animals; Blotting, Western; Caffeic Acids; Cardiomegaly; Cell Line; Disease Models, Animal; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Phenylephrine; Phenylethyl Alcohol; Polymerase Chain Reaction; Rats; Resveratrol; Smad Proteins; Stilbenes; Transforming Growth Factor beta | 2017 |
Caffeic acid phenethyl ester protects the brain against hexavalent chromium toxicity by enhancing endogenous antioxidants and modulating the JAK/STAT signaling pathway.
Topics: Acetylcholinesterase; Animals; Antioxidants; Caffeic Acids; Cerebrum; Chromium; Down-Regulation; Glutathione; Glutathione Peroxidase; Inflammation; Janus Kinases; Lipid Peroxidation; Male; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Phosphorylation; Rats, Wistar; RNA, Messenger; Signal Transduction; STAT Transcription Factors; Superoxide Dismutase; Suppressor of Cytokine Signaling 3 Protein | 2017 |
Is caffeic acid phenethyl ester more protective than doxycycline in experimental periodontitis?
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caffeic Acids; Cytokines; Disease Models, Animal; Doxycycline; Enzyme-Linked Immunosorbent Assay; Lipid Peroxidation; Male; Oxidants; Oxidative Stress; Periodontitis; Phenylethyl Alcohol; Rats; Rats, Wistar | 2017 |
Synergistic antitumor effect of NVP-BEZ235 and CAPE on MDA-MB-231 breast cancer cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Female; Forkhead Box Protein O3; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Neoplasm Proteins; Phenylethyl Alcohol; Phosphorylation; Protein Processing, Post-Translational; Quinolines; Receptors, CXCR4; Triple Negative Breast Neoplasms | 2017 |
Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Colitis, Ulcerative; Cytokines; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Female; Inflammation; Inflammation Mediators; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Protective Agents | 2018 |
The effect of caffeic acid phenethyl ester (CAPE) on tympanosclerosis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Inflammation; Male; Middle Ear Ventilation; Myringosclerosis; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Tympanic Membrane | 2017 |
New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis.
Topics: Arachidonate 5-Lipoxygenase; Caffeic Acids; Coumaric Acids; Enzyme Activation; Hydroxyurea; Leukotrienes; Lipoxygenase Inhibitors; Phenylethyl Alcohol; Structure-Activity Relationship | 2017 |
3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells.
Topics: Autophagy; Caffeic Acids; Cell Line, Tumor; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Neurons; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Phenylethyl Alcohol; Signal Transduction; Time Factors; Unfolded Protein Response | 2018 |
Caffeic Acid Phenethyl Ester from the Twigs of Cinnamomum cassia Inhibits Malignant Cell Transformation by Inducing c-Fos Degradation.
Topics: Anticarcinogenic Agents; Caffeic Acids; Cinnamomum aromaticum; Molecular Structure; Phenylethyl Alcohol; Plant Stems; Proto-Oncogene Proteins c-fos; Republic of Korea; Signal Transduction; Transcription Factor AP-1 | 2017 |
Substituted Caffeic and Ferulic Acid Phenethyl Esters: Synthesis, Leukotrienes Biosynthesis Inhibition, and Cytotoxic Activity.
Topics: Arachidonate 5-Lipoxygenase; Caffeic Acids; Cell Death; Cell Line, Tumor; Cell Survival; Coumaric Acids; HEK293 Cells; Humans; Imaging, Three-Dimensional; Leukotrienes; Ligands; Lipoxygenase Inhibitors; Molecular Docking Simulation; Phenylethyl Alcohol; Thermodynamics | 2017 |
Metabolomics study of cadmium-induced diabetic nephropathy and protective effect of caffeic acid phenethyl ester using UPLC-Q-TOF-MS combined with pattern recognition.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Cadmium; Caffeic Acids; Catalase; Diabetic Nephropathies; Glutathione; Kidney; Lipid Metabolism; Male; Metabolomics; Mice; Oxidative Stress; Pattern Recognition, Automated; Phenylethyl Alcohol; Superoxide Dismutase; Tandem Mass Spectrometry | 2017 |
Caffeic Acid Phenethyl Ester (Propolis Extract) Ameliorates Insulin Resistance by Inhibiting JNK and NF-κB Inflammatory Pathways in Diabetic Mice and HepG2 Cell Models.
Topics: Animals; Caffeic Acids; Diabetes Mellitus, Type 2; Glucose-6-Phosphatase; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Phenylethyl Alcohol; Propolis; Signal Transduction | 2017 |
Effects of propolis, caffeic acid phenethyl ester, and pollen on renal injury in hypertensive rat: An experimental and theoretical approach.
Topics: Animals; Antioxidants; Arginine; Aryldialkylphosphatase; Binding Sites; Caffeic Acids; Glutathione Reductase; Half-Life; Hypertension; Kidney Diseases; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Pollen; Propolis; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley | 2017 |
Glycosylation Enhances the Physicochemical Properties of Caffeic Acid Phenethyl Ester.
Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Caffeic Acids; Cell Survival; Deinococcus; Enzyme Stability; Gene Expression Regulation; Glucosyltransferases; Glycosides; Glycosylation; Hydrogen-Ion Concentration; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Mice; NF-E2-Related Factor 2; Nitric Oxide; Phenylethyl Alcohol; RAW 264.7 Cells; Solubility; Temperature | 2017 |
Concurrent treatment with simvastatin and NF-κB inhibitor in human castration-resistant prostate cancer cells exerts synergistic anti-cancer effects via control of the NF-κB/LIN28/let-7 miRNA signaling pathway.
Topics: Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; NF-kappa B; Phenylethyl Alcohol; Prostatic Neoplasms, Castration-Resistant; RNA-Binding Proteins; Signal Transduction; Simvastatin | 2017 |
Protective Effect of Combined Caffeic Acid Phenethyl Ester and Bevacizumab Against Hydrogen Peroxide-Induced Oxidative Stress in Human RPE Cells.
Topics: Angiogenesis Inhibitors; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Bevacizumab; Caffeic Acids; Caspase 3; Cell Line; Cell Survival; Cytochromes c; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Hydrogen Peroxide; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Retinal Pigment Epithelium; Vascular Endothelial Growth Factor A | 2017 |
Ethanol extract of propolis and its constituent caffeic acid phenethyl ester inhibit breast cancer cells proliferation in inflammatory microenvironment by inhibiting TLR4 signal pathway and inducing apoptosis and autophagy.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Autophagy; Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Ethanol; Female; Humans; Phenylethyl Alcohol; Propolis; Signal Transduction; Toll-Like Receptor 4; Tumor Microenvironment | 2017 |
Apoptosis induced by caffeic acid phenethyl ester in human oral cancer cell lines: Involvement of Puma and Bax activation.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Biomarkers, Tumor; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Cell Transformation, Neoplastic; Humans; Immunohistochemistry; Mouth Neoplasms; Phenylethyl Alcohol; Proto-Oncogene Proteins; Staining and Labeling | 2017 |
Migration Rate Inhibition of Breast Cancer Cells Treated by Caffeic Acid and Caffeic Acid Phenethyl Ester: An In Vitro Comparison Study.
Topics: Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Female; Humans; Mitochondria; Phenylethyl Alcohol; Propolis | 2017 |
Antifilarial activity of caffeic acid phenethyl ester on Brugia pahangi in vitro and in vivo.
Topics: Animals; Brugia pahangi; Caffeic Acids; Dose-Response Relationship, Drug; Filariasis; Gerbillinae; Humans; Male; Phenylethyl Alcohol; Wolbachia | 2017 |
Structure, antioxidative potency and potential scavenging of OH and OOH of phenylethyl-3,4-dihydroxyhydrocinnamate in protic and aprotic media: DFT study.
Topics: Antioxidants; Caffeic Acids; Hydrogen; Hydroxides; Hydroxyl Radical; Oxidation-Reduction; Phenylethyl Alcohol; Solvents; Thermodynamics; Water | 2017 |
Marker-based standardization and investigation of nutraceutical potential of Indian propolis.
Topics: Animals; Antioxidants; Bees; Caffeic Acids; Chromatography, High Pressure Liquid; Dietary Supplements; Ethanol; Flavanones; Flavonoids; Humans; India; Nutritive Value; Phenylethyl Alcohol; Plant Extracts; Polyphenols; Propolis | 2017 |
Caffeic acid phenethyl ester promotes haematopoietic stem/progenitor cell homing and engraftment.
Topics: Animals; Caffeic Acids; Cells, Cultured; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred C57BL; Phenylethyl Alcohol; Stem Cells | 2017 |
Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Cytokines; Dose-Response Relationship, Drug; Drug Discovery; Humans; Inflammation; Lipopolysaccharides; Lymphocyte Antigen 96; Macrophages; Mice; Mice, Inbred C57BL; Molecular Structure; Phenylethyl Alcohol; Structure-Activity Relationship | 2018 |
Caffeic Acid Phenethyl Ester (CAPE) Protects PC12 Cells from Cisplatin-Induced Neurotoxicity by Activating the NGF-Signaling Pathway.
Topics: Analysis of Variance; Animals; Caffeic Acids; Cell Differentiation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibitors; GAP-43 Protein; Nerve Growth Factor; Neuroblastoma; Neurofilament Proteins; Neuronal Outgrowth; Neuroprotective Agents; Neurotoxins; PC12 Cells; Phenylethyl Alcohol; Rats; Signal Transduction; Synapsins; Synaptophysin | 2018 |
Antioxidant activity of CAPE (caffeic acid phenethyl ester) in vitro can protect human sperm deoxyribonucleic acid from oxidative damage.
Topics: Antioxidants; Caffeic Acids; Humans; Male; Microscopy, Electron, Transmission; Oxidative Stress; Phenylethyl Alcohol; Semen Analysis; Spermatozoa | 2018 |
Anticancer Activity in Honeybee Propolis: Functional Insights to the Role of Caffeic Acid Phenethyl Ester and Its Complex With γ-Cyclodextrin.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apitherapy; Caffeic Acids; Drug Combinations; Female; gamma-Cyclodextrins; HeLa Cells; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Phenylethyl Alcohol; Propolis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2018 |
Aspergillus niger whole-cell catalyzed synthesis of caffeic acid phenethyl ester in ionic liquids.
Topics: Alcohols; Aspergillus niger; Biocatalysis; Bioreactors; Caffeic Acids; Esterification; Fungal Proteins; Ionic Liquids; Kinetics; Lipase; Phenylethyl Alcohol; Solubility; Temperature | 2018 |
Chlorpyrifos-induced parkinsonian model in mice: Behavior, histopathology and biochemistry.
Topics: Animals; Antioxidants; Aryldialkylphosphatase; Brain; Caffeic Acids; Chlorpyrifos; Disease Models, Animal; Insecticides; Lipid Metabolism; Male; Mice; Motor Activity; N-Acetylneuraminic Acid; Neuroprotective Agents; Parkinsonian Disorders; Phenylethyl Alcohol | 2018 |
Caffeic acid phenethyl ester rescued streptozotocin-induced memory loss through PI3-kinase dependent pathway.
Topics: Animals; Caffeic Acids; Female; Male; Maze Learning; Memory Disorders; Oxidative Stress; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Rats; Rats, Wistar; Signal Transduction; Streptozocin | 2018 |
Caffeic acid phenethyl ester synergistically enhances the antifungal activity of fluconazole against resistant Candida albicans.
Topics: Animals; Antifungal Agents; Caenorhabditis elegans; Caffeic Acids; Candida albicans; Candidiasis; Disease Models, Animal; Drug Resistance, Fungal; Drug Synergism; Drug Therapy, Combination; Fluconazole; Microbial Sensitivity Tests; Phenylethyl Alcohol | 2018 |
Caffeic Acid Phenethyl Ester Improves Metabolic Syndrome by Activating PPAR-γ and Inducing Adipose Tissue Remodeling in Diet-Induced Obese Mice.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Body Weight; Caffeic Acids; Diet, High-Fat; Hyperlipidemias; Insulin Resistance; Male; Metabolic Syndrome; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Organ Size; Panniculitis; Phenylethyl Alcohol; PPAR gamma | 2018 |
Attenuating effects of caffeic acid phenethyl ester and betaine on abamectin-induced hepatotoxicity and nephrotoxicity.
Topics: Animals; Antioxidants; Betaine; Caffeic Acids; Catalase; Chemical and Drug Induced Liver Injury; Creatinine; Glutathione; Glutathione Peroxidase; Ivermectin; Kidney; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2018 |
Caffeic acid phenethyl ester down-regulates claudin-2 expression at the transcriptional and post-translational levels and enhances chemosensitivity to doxorubicin in lung adenocarcinoma A549 cells.
Topics: A549 Cells; Adenocarcinoma of Lung; Caffeic Acids; Cantharidin; Cell Line, Tumor; Cell Proliferation; Chloroquine; Claudins; Down-Regulation; Doxorubicin; Drug Synergism; Fatty Acids; Gene Expression Regulation; Humans; Lung Neoplasms; Lysosomes; Permeability; Phenylethyl Alcohol; Promoter Regions, Genetic; Propolis; RNA, Messenger; Tight Junctions | 2018 |
Caffeic acid phenethyl ester guards against benign prostate hypertrophy in rats: Role of IGF-1R/protein kinase-B (Akt)/β-catenin signaling.
Topics: Animals; beta Catenin; Caffeic Acids; Gene Expression Regulation, Neoplastic; Male; Phenylethyl Alcohol; Prostatic Hyperplasia; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1 | 2018 |
Synergistic effect of caffeic acid phenethyl ester with caspofungin against Candida albicans is mediated by disrupting iron homeostasis.
Topics: Antifungal Agents; Caffeic Acids; Candida albicans; Caspofungin; Drug Synergism; Echinocandins; Homeostasis; Iron; Lipopeptides; Microbial Sensitivity Tests; Mitochondria; Phenylethyl Alcohol; Reactive Oxygen Species | 2018 |
Caffeic acid phenethyl ester inhibits the progression of ovarian cancer by regulating NF-?B signaling.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Survival; Disease Progression; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Ovarian Neoplasms; Phenylethyl Alcohol; Phosphorylation; Signal Transduction; Transcription Factor RelA; Xenograft Model Antitumor Assays | 2018 |
Caffeic Acid Phenethyl Ester Induces
Topics: Apoptosis; Caffeic Acids; Carcinoma; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intracellular Signaling Peptides and Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Phenylethyl Alcohol; Phosphorylation; Signal Transduction; STAT3 Transcription Factor | 2018 |
Antibacterial and antioxidant electrospun materials from poly(3-hydroxybutyrate) and polyvinylpyrrolidone containing caffeic acid phenethyl ester - "in" and "on" strategies for enhanced solubility.
Topics: Anti-Bacterial Agents; Antioxidants; Biphenyl Compounds; Caffeic Acids; Calorimetry, Differential Scanning; Crystallography, X-Ray; Dosage Forms; Drug Compounding; Escherichia coli; Hydroxybutyrates; Microscopy, Electron, Scanning; Phenylethyl Alcohol; Picrates; Polyesters; Povidone; Solubility; Spectroscopy, Fourier Transform Infrared; Staphylococcus aureus; Technology, Pharmaceutical | 2018 |
Anti-glioma Effects of Caffeic Acid Phenethyl Ester and Dasatinib Combination Therapy in an in vivo Rat Glioma Model.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Proliferation; Dasatinib; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Glioma; Male; Molecular Structure; Phenylethyl Alcohol; Rats; Rats, Wistar; Structure-Activity Relationship; Tumor Cells, Cultured | 2018 |
Caffeic acid phenethyl ester promotes wound healing of mice pressure ulcers affecting NF-κB, NOS2 and NRF2 expression.
Topics: Animals; Caffeic Acids; Disease Models, Animal; Gene Expression Regulation; Inflammation; Lipid Peroxidation; Male; Mice; NF-E2-Related Factor 2; NF-kappa B p50 Subunit; Nitric Oxide Synthase Type II; Oxidative Stress; Phenylethyl Alcohol; Pressure Ulcer; Reactive Oxygen Species; Reperfusion Injury; Skin; Wound Healing | 2018 |
Caffeic acid phenethyl ester (CAPE) possesses pro-hypoxia and anti-stress activities: bioinformatics and experimental evidences.
Topics: Caffeic Acids; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Computational Biology; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mixed Function Oxygenases; Molecular Docking Simulation; Phenylethyl Alcohol; Protein Aggregates; Stress, Physiological | 2018 |
Effects of caffeic acid phenethyl ester application on dentin MMP-2, stability of bond strength and failure mode of total-etch and self-etch adhesive systems.
Topics: Acid Etching, Dental; Analysis of Variance; Caffeic Acids; Composite Resins; Dental Bonding; Dental Cements; Dental Restoration Failure; Dentin; Dentin-Bonding Agents; Glass Ionomer Cements; Humans; In Vitro Techniques; Materials Testing; Matrix Metalloproteinase 2; Microscopy, Electron, Scanning; Molar, Third; Phenylethyl Alcohol; Resin Cements; Stress, Mechanical; Surface Properties; Tensile Strength | 2018 |
Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI.
Topics: Amino Acid Oxidoreductases; AMP-Activated Protein Kinases; Animals; Antioxidants; Behavior Rating Scale; Brain Injuries, Traumatic; Caffeic Acids; Disease Models, Animal; Drug Synergism; Dynamins; GTP Phosphohydrolases; Heme Oxygenase-1; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Neurons; Neuroprotective Agents; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenylethyl Alcohol; Protein Serine-Threonine Kinases; S-Nitrosoglutathione; Superoxide Dismutase | 2018 |
Inhibition of nuclear factor-κB p65 phosphorylation by 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Nucleus; Depression, Chemical; Inflammation; Interleukin-1beta; Mice; NF-kappa B; Nitric Oxide Synthase; Nitrites; Phenylethyl Alcohol; Phosphorylation; RAW 264.7 Cells; Signal Transduction | 2018 |
Development of a biodegradable antifibrotic local drug delivery system for glaucoma microstents.
Topics: Animals; Caffeic Acids; Drug Delivery Systems; Drug-Eluting Stents; Fibrosis; Glaucoma; Male; Paclitaxel; Phenylethyl Alcohol; Pyridones; Rats; Rats, Wistar | 2018 |
Caffeic acid phenethyl ester (CAPE) reverses fibrosis caused by chronic colon inflammation in murine model of colitis.
Topics: Animals; Caffeic Acids; Colitis; Colon; Disease Models, Animal; Female; Fibrosis; Inflammation; Mice; Mice, Inbred C57BL; Phenylethyl Alcohol | 2018 |
Effects of Intrathecal Caffeic Acid Phenethyl Ester (CAPE) on IL-6 and TNF-α Levels and Local Inflammatory Responses in Spinal Cord Injuries.
Topics: Animals; Caffeic Acids; Edema; Female; Hemorrhage; Injections, Spinal; Interleukin-6; Methylprednisolone; Phenylethyl Alcohol; Rats; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2018 |
Caffeic Acid Versus Caffeic Acid Phenethyl Ester in the Treatment of Breast Cancer MCF-7 Cells: Migration Rate Inhibition.
Topics: Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; MCF-7 Cells; Phenylethyl Alcohol | 2018 |
Albumin nano-encapsulation of caffeic acid phenethyl ester and piceatannol potentiated its ability to modulate HIF and NF-kB pathways and improves therapeutic outcome in experimental colitis.
Topics: Albumins; Animals; Biological Availability; Caffeic Acids; Colitis; Dextran Sulfate; Disease Models, Animal; Drug Combinations; Drug Compounding; Drug Synergism; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Nanoparticles; Particle Size; Phenylethyl Alcohol; Signal Transduction; Stilbenes; Transcription Factor RelA | 2019 |
Caffeic acid phenethyl ester exerts apoptotic and oxidative stress on human multiple myeloma cells.
Topics: Antioxidants; Apoptosis; Biomarkers, Tumor; Caffeic Acids; Cell Movement; Cell Proliferation; Gene Expression Profiling; Humans; Multiple Myeloma; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species; Tumor Cells, Cultured | 2019 |
Caffeic acid phenethyl ester potentiates gastric cancer cell sensitivity to doxorubicin and cisplatin by decreasing proteasome function.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caffeic Acids; Cell Proliferation; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Drug Therapy, Combination; Humans; Phenylethyl Alcohol; Proteasome Endopeptidase Complex; Stomach Neoplasms; Tumor Cells, Cultured | 2019 |
Evaluation of PECAM-1 and p38 MAPK expressions in cerebellum tissue of rats treated with caffeic acid phenethyl ester: a biochemical and immunohistochemical study.
Topics: Animals; Caffeic Acids; Catalase; Cerebellum; Glutathione Peroxidase; Immunohistochemistry; Male; Malondialdehyde; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Platelet Endothelial Cell Adhesion Molecule-1; Rats, Sprague-Dawley; Superoxide Dismutase | 2019 |
Synthesis of Diverse Hydroxycinnamoyl Phenylethanoid Esters Using Escherichia coli.
Topics: Caffeic Acids; Coumaric Acids; Escherichia coli; Esterification; Esters; Glucose; Mannosyltransferases; Oryza; Phenylethyl Alcohol; Transformation, Bacterial | 2019 |
Repurposing nitrocatechols: 5-Nitro-α-cyanocarboxamide derivatives of caffeic acid and caffeic acid phenethyl ester effectively inhibit aggregation of tau-derived hexapeptide AcPHF6.
Topics: Caffeic Acids; Catechols; Chelating Agents; Copper; Drug Design; Nitro Compounds; Peptides; Phenylethyl Alcohol; Polyphenols; Protein Aggregation, Pathological; Small Molecule Libraries; tau Proteins; Tauopathies | 2019 |
Caffeic acid phenethyl ester protects against oxidative stress and dampens inflammation via heme oxygenase 1.
Topics: Animals; Caffeic Acids; Heme Oxygenase-1; Humans; Inflammation; Mice; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol | 2019 |
Protective effects of caffeic acid phenethyl ester and thymoquinone on toluene induced liver toxicity.
Topics: Animals; Benzoquinones; Caffeic Acids; Chemical and Drug Induced Liver Injury; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Toluene | 2019 |
Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties.
Topics: Animals; Biphenyl Compounds; Caffeic Acids; Cattle; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Models, Molecular; Molecular Structure; Phenylethyl Alcohol; Picrates; Reactive Oxygen Species; Structure-Activity Relationship; Xanthine Oxidase | 2019 |
Inhibitory Effect of CAPE and Kaempferol in Colon Cancer Cell Lines-Possible Implications in New Therapeutic Strategies.
Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Proliferation; Cell Survival; Colonic Neoplasms; HCT116 Cells; Humans; Kaempferols; Neoplasm Invasiveness; Phenylethyl Alcohol | 2019 |
Caffeic Acid Phenethyl Ester Rescues Pulmonary Arterial Hypertension through the Inhibition of AKT/ERK-Dependent PDGF/HIF-1α In Vitro and In Vivo.
Topics: Animals; Apoptosis; Caffeic Acids; Cell Line; Cell Proliferation; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Phenylethyl Alcohol; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Rats; Signal Transduction; Vascular Remodeling | 2019 |
Transglycosylation Improved Caffeic Acid Phenethyl Ester Anti-Inflammatory Activity and Water Solubility by Leuconostoc mesenteroides Dextransucrase.
Topics: Animals; Anti-Inflammatory Agents; Bacterial Proteins; Biocatalysis; Caffeic Acids; Glucosyltransferases; Interleukin-6; Leuconostoc mesenteroides; Macrophages; Mice; Molecular Structure; Phenylethyl Alcohol; RAW 264.7 Cells; Solubility; Tumor Necrosis Factor-alpha | 2019 |
Cardioprotective effect of caffeic acid phenethyl ester on cardiac contusion following blunt chest trauma in rats.
Topics: Animals; Antioxidants; Apoptosis; Caffeic Acids; Heart; Male; Myocardial Contusions; Myocardium; Phenylethyl Alcohol; Rats, Wistar; Thoracic Injuries; Wounds, Nonpenetrating | 2019 |
Effects of caffeic acid phenethyl ester (CAPE) on angiogenesis, apoptosis and oxidatıve stress ın various cancer cell lines.
Topics: Angiogenesis Inducing Agents; Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Neovascularization, Pathologic; Oxidative Stress; Phenylethyl Alcohol; Propolis | 2019 |
Caffeic Acid Phenethyl Ester (CAPE) Protects PC12 Cells Against Cisplatin-Induced Neurotoxicity by Activating the AMPK/SIRT1, MAPK/Erk, and PI3k/Akt Signaling Pathways.
Topics: AMP-Activated Protein Kinases; Animals; Caffeic Acids; Cell Differentiation; Chlorocebus aethiops; Cisplatin; COS Cells; Cytoskeletal Proteins; Glucose; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; PC12 Cells; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; Sirtuin 1 | 2019 |
Caffeic acid phenethyl ester attenuates nuclear factor‑κB‑mediated inflammatory responses in Müller cells and protects against retinal ganglion cell death.
Topics: Animals; Astrocytes; Caffeic Acids; Cell Death; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Survival; Chemokine CCL2; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Ependymoglial Cells; Glaucoma; Gliosis; In Situ Nick-End Labeling; Inflammation; Interleukin-6; Interleukin-8; Lipopolysaccharides; Male; NF-kappa B; Nitric Oxide Synthase Type II; Optic Nerve Injuries; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Signal Transduction; Transcription Factor Brn-3A; Tumor Necrosis Factor-alpha | 2019 |
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats.
Topics: Amidohydrolases; Animals; Antioxidants; Caffeic Acids; Diabetes Mellitus, Experimental; Glutamate-Cysteine Ligase; Heme Oxygenase (Decyclizing); Male; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Propolis; Rats; Rats, Wistar; Streptozocin; Up-Regulation | 2019 |
Caffeic acid phenethyl ester suppressed growth and metastasis of nasopharyngeal carcinoma cells by inactivating the NF-κB pathway.
Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; NF-kappa B; Phenylethyl Alcohol; Structure-Activity Relationship; Tumor Cells, Cultured; Wound Healing | 2019 |
Caffeic Acid Phenethyl Ester Inhibits UV-Induced MMP-1 Expression by Targeting Histone Acetyltransferases in Human Skin.
Topics: Caffeic Acids; Fibroblasts; Gene Expression Regulation; Histone Acetyltransferases; Humans; Matrix Metalloproteinase 1; Phenylethyl Alcohol; Skin; Ultraviolet Rays | 2019 |
Caffeic Acid Esters Are Effective Bactericidal Compounds Against
Topics: Anti-Bacterial Agents; Caffeic Acids; Glutathione; Microbial Sensitivity Tests; Paenibacillus larvae; Phenylethyl Alcohol; Plant Extracts; Propolis; Reactive Oxygen Species | 2019 |
Caffeic Acid Phenethyl Ester Inhibits the Proliferation of HEp2 Cells by Regulating Stat3/Plk1 Pathway and Inducing S Phase Arrest.
Topics: Antineoplastic Agents, Phytogenic; Caffeic Acids; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Humans; Laryngeal Neoplasms; Phenylethyl Alcohol; Polo-Like Kinase 1; Polyphenols; Propolis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; S Phase; STAT3 Transcription Factor | 2019 |
Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213.
Topics: Caffeic Acids; Dose-Response Relationship, Drug; Humans; Phenylethyl Alcohol; Phosphorylation; Receptors, Androgen; Serine; Signal Transduction; Structure-Activity Relationship; Tumor Cells, Cultured | 2019 |
Caffeic acid phenethyl ester ameliorates pulmonary inflammation and apoptosis reducing Nf-κβ activation in blunt pulmonary contusion model.
Topics: Animals; Apoptosis; Caffeic Acids; Lung Injury; NF-kappa B; Phenylethyl Alcohol; Pneumonia; Rats; Rats, Wistar | 2019 |
Depolarization of pacemaker potentials by caffeic acid phenethyl ester in interstitial cells of Cajal from the murine small intestine.
Topics: Animals; Caffeic Acids; Calcium; Gastrointestinal Motility; Interstitial Cells of Cajal; Intestine, Small; Membrane Potentials; Mice; Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Phenylethyl Alcohol; Protein Kinase Inhibitors; Thapsigargin | 2020 |
An evaluation of the effects of caffeic acid phenethyl ester and Ankaferd blood stopper on secondary wound healing of oral mucosal tissue
Topics: Animals; Caffeic Acids; Drug Administration Schedule; Gene Expression; Male; Mouth Mucosa; Phenylethyl Alcohol; Plant Extracts; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Wound Healing | 2020 |
Caffeic acid phenethyl ester attenuates changes in pancreatic tissue damage biomarkers induced by cisplatin.
Topics: Animals; Biomarkers; Caffeic Acids; Cisplatin; Cytoprotection; Male; Necrosis; Pancreas; Phenylethyl Alcohol; Rats; Rats, Wistar | 2020 |
FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Protects against Oxidative Stress-Mediated Neuronal Cell Apoptosis and Scopolamine-Induced Cognitive Impairment by Activating Nrf2/HO-1 Signaling.
Topics: Alzheimer Disease; Animals; Apoptosis; Caffeic Acids; Cognitive Dysfunction; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Humans; Male; Mice; Mice, Inbred Strains; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; PC12 Cells; Phenylethyl Alcohol; Rats; RNA, Small Interfering; Scopolamine; Signal Transduction | 2019 |
Investigation of the preventive effects of dehydroepiandrosterone (DHEA) and Caffeic acid phenethyl ester (CAPE) on cisplatin-induced ovarian damage in rats.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cisplatin; Dehydroepiandrosterone; Female; Ovarian Reserve; Ovary; Phenylethyl Alcohol; Rats; Rats, Wistar | 2020 |
Caffeic Acid Phenethyl Ester (CAPE) Induces VEGF Expression and Production in Rat Odontoblastic Cells.
Topics: Animals; Apoptosis; Caffeic Acids; Cell Line; Dental Caries; Dental Pulp Calcification; I-kappa B Proteins; Inflammation; NF-kappa B; Odontoblasts; Phenylethyl Alcohol; Propolis; Rats; Transcriptional Activation; Vascular Endothelial Growth Factor A | 2019 |
Enhanced antibacterial and antiparasitic activity of multifunctional polymeric nanoparticles.
Topics: Anti-Bacterial Agents; Antiparasitic Agents; Caffeic Acids; Escherichia coli; Leishmania; Microbial Sensitivity Tests; Nanoparticles; Naphthoquinones; Particle Size; Phenylethyl Alcohol; Polylactic Acid-Polyglycolic Acid Copolymer; Staphylococcus aureus | 2020 |
FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Ameliorates DSS-Induced Colitis Against Oxidative Stress by Activating Nrf2/HO-1 Pathway.
Topics: Animals; Antioxidants; Caffeic Acids; Cells, Cultured; Colitis; Dextran Sulfate; Female; Heme Oxygenase-1; Inflammatory Bowel Diseases; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol; RAW 264.7 Cells; Signal Transduction | 2019 |
A biochemical and immunohistochemical study of the effects of caffeic acid phenethyl ester on alveolar bone loss and oxidative stress in diabetic rats with experimental periodontitis.
Topics: Alveolar Bone Loss; Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Oxidative Stress; Periodontitis; Phenylethyl Alcohol; Rats, Wistar; Streptozocin | 2020 |
Antagonistic Effects of CAPE (a Component of Propolis) on the Cytotoxicity and Genotoxicity of Irinotecan and SN38 in Human Gastrointestinal Cancer Cells In Vitro.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cytotoxins; DNA Damage; Drug Synergism; HCT116 Cells; HT29 Cells; Humans; Hydrogen Peroxide; Irinotecan; Lymphocytes; Mutagens; Oxidative Stress; Phenylethyl Alcohol; Propolis; Topoisomerase I Inhibitors | 2020 |
A caffeic acid phenethyl ester analog inhibits the proliferation of nasopharyngeal carcinoma cells via targeting epidermal growth factor receptor.
Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; ErbB Receptors; Fibroblasts; Gene Expression; HeLa Cells; Humans; MCF-7 Cells; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Phenylethyl Alcohol; Signal Transduction | 2020 |
The Impact of Propolis Factor Caffeic Acid Phenethyl-Ester on the Cerebral Vasospasm and Early Brain Damage in the Experimentally Induced Subarachnoid Hemorrhage on Rats.
Topics: Animals; CA3 Region, Hippocampal; Caffeic Acids; Disease Models, Animal; Neurons; Neuroprotective Agents; Phenylethyl Alcohol; Propolis; Rats, Wistar; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2020 |
Protective effect of caffeic acid phenethyl ester against imidacloprid-induced hepatotoxicity by attenuating oxidative stress, endoplasmic reticulum stress, inflammation and apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Caffeic Acids; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum Stress; Humans; Inflammation; Mice; Neonicotinoids; Nitro Compounds; Oxidative Stress; Phenylethyl Alcohol | 2020 |
Inhibiting the NF-κB pathway enhances the antitumor effect of cabazitaxel by downregulating Bcl-2 in pancreatic cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; NF-kappa B; Pancreatic Neoplasms; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Taxoids; Xenograft Model Antitumor Assays | 2020 |
Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (M
Topics: Caffeic Acids; COVID-19; Humans; Molecular Docking Simulation; Peptide Hydrolases; Phenylethyl Alcohol; Protease Inhibitors; SARS-CoV-2; Withanolides | 2021 |
Long-term Evaluation of Dentin Matrix Stability and Gelatinolytic Activity after Dentin Pretreatment with Caffeic Acid Phenethyl Ester.
Topics: Caffeic Acids; Dental Bonding; Dental Cements; Dentin; Dentin-Bonding Agents; Materials Testing; Phenylethyl Alcohol; Tensile Strength | 2020 |
Integrated Analysis of mRNA-seq and miRNA-seq to Identify c-MYC, YAP1 and miR-3960 as Major Players in the Anticancer Effects of Caffeic Acid Phenethyl Ester in Human Small Cell Lung Cancer Cell Line.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Phenylethyl Alcohol; Proto-Oncogene Proteins c-myc; RNA-Seq; Small Cell Lung Carcinoma; Transcription Factors; YAP-Signaling Proteins | 2020 |
Antibacterial Effect of Caffeic Acid Phenethyl Ester on Cariogenic Bacteria and Streptococcus mutans Biofilms.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Caffeic Acids; Dental Caries; Humans; Phenylethyl Alcohol; Streptococcus mutans | 2020 |
Research on the protective effect of caffeic acid phenethyl ester on testicular damage caused by cisplatin
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cisplatin; Disease Models, Animal; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Testicular Diseases; Testis | 2020 |
Evaluation of the neuroprotective potential of caffeic acid phenethyl ester in a cellular model of Parkinson's disease.
Topics: Antiparkinson Agents; Apoptosis; Apoptosis Regulatory Proteins; Caffeic Acids; Cell Line, Tumor; Humans; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; Phenylethyl Alcohol; Reactive Oxygen Species; Signal Transduction | 2020 |
Caffeic Acid Phenethyl Ester (CAPE) Induced Apoptosis in Serous Ovarian Cancer OV7 Cells by Deregulation of BCL2/BAX Genes.
Topics: Antineoplastic Agents; Apoptosis; Autophagosomes; bcl-2-Associated X Protein; Caffeic Acids; Cell Line, Tumor; Cell Survival; Female; Gene Expression; Humans; Ovarian Neoplasms; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2 | 2020 |
Mechanism of synergistic DNA damage induced by caffeic acid phenethyl ester (CAPE) and Cu(II): Competitive binding between CAPE and DNA with Cu(II)/Cu(I).
Topics: Animals; Binding, Competitive; Caffeic Acids; Copper; DNA; DNA Damage; Hydrogen Peroxide; Phenylethyl Alcohol | 2020 |
Caffeic acid phenethyl ester, a coffee polyphenol, inhibits DNA methylation in vitro and in vivo.
Topics: Animals; Caffeic Acids; Coffee; DNA Methylation; Dose-Response Relationship, Drug; Epigenesis, Genetic; Female; HT29 Cells; Humans; Male; Mice; Mice, Transgenic; Molecular Docking Simulation; Phenylethyl Alcohol; Polyphenols; Pregnancy; Prenatal Exposure Delayed Effects; Protein Structure, Secondary; Salmon | 2020 |
The investigation of antioxidant and anti-inflammatory potentials of apitherapeutic agents on heart tissues in nitric oxide synthase inhibited rats via Nω-nitro-L-arginine methyl ester.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Aryldialkylphosphatase; Blood Pressure; Caffeic Acids; Free Radical Scavengers; Male; Myocardium; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Pollen; Propolis; Rats; Rats, Sprague-Dawley | 2021 |
Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain in Sprague-Dawley rats: Emphasis on the modulation of oxidative stress and neuroinflammation.
Topics: Animals; Antibiotics, Antineoplastic; Avoidance Learning; Brain Chemistry; Caffeic Acids; Caspase 3; Chemotherapy-Related Cognitive Impairment; Doxorubicin; Encephalitis; Glial Fibrillary Acidic Protein; Hippocampus; Inflammation Mediators; Male; Maze Learning; Memory; Motor Activity; Neuroprotective Agents; Oxidative Stress; Phenylethyl Alcohol; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2020 |
Caffeic Acid Phenethyl Ester Loaded in Skim Milk Microcapsules: Physicochemical Properties and Enhanced
Topics: Animals; Biological Availability; Caffeic Acids; Cattle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Drug Compounding; Milk; Phenylethyl Alcohol | 2020 |
Antimyeloma Potential of Caffeic Acid Phenethyl Ester and Its Analogues through Sp1 Mediated Downregulation of IKZF1-IRF4-MYC Axis.
Topics: Angiogenesis Inhibitors; Apoptosis; Caffeic Acids; Cell Line, Tumor; Down-Regulation; Genes, myc; Humans; Ikaros Transcription Factor; Interferon Regulatory Factors; Lenalidomide; Multiple Myeloma; Phenylethyl Alcohol; Sp1 Transcription Factor; Structure-Activity Relationship | 2020 |
The effect of caffeic acid phenethyl ester and Ankaferd Blood Stopper on the diabetic and nondiabetic gingival wound healing: an experimental study
Topics: Animals; Caffeic Acids; Diabetes Mellitus; Male; Mouth Mucosa; Phenylethyl Alcohol; Plant Extracts; Rats; Rats, Wistar; Wound Healing | 2021 |
Propolis Suppresses UV-Induced Photoaging in Human Skin through Directly Targeting Phosphoinositide 3-Kinase.
Topics: Apigenin; Caffeic Acids; Collagen; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Plant Extracts; Propolis; Quercetin; Skin; Skin Aging; Ultraviolet Rays | 2020 |
Synergic antioxidant activity of γ-terpinene with phenols and polyphenols enabled by hydroperoxyl radicals.
Topics: Antioxidants; Caffeic Acids; Chromans; Cyclohexane Monoterpenes; Drug Synergism; Peroxides; Phenols; Phenylethyl Alcohol; Polyphenols | 2021 |
Discovery of CAPE derivatives as dual EGFR and CSK inhibitors with anticancer activity in a murine model of hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Binding Sites; Caffeic Acids; Carcinoma, Hepatocellular; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Liver Neoplasms; Male; Mice; Molecular Docking Simulation; Phenylethyl Alcohol; src-Family Kinases; Structure-Activity Relationship | 2021 |
Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives.
Topics: Caffeic Acids; Cathepsin B; Cathepsin L; Chlorogenic Acid; Drug Discovery; Enzyme Inhibitors; Humans; Phenylethyl Alcohol; Proteolysis | 2020 |
Formulation Development of Folic Acid Conjugated PLGA Nanoparticles for Improved Cytotoxicity of Caffeic Acid Phenethyl Ester.
Topics: Caffeic Acids; Folic Acid; Nanoparticles; Phenylethyl Alcohol | 2021 |
Effects of Caffeic Acid Phenethyl Ester and Oxidative Stress Caused by the Exhaustion Exercise on Endotelial Damage.
Topics: Animals; Antioxidants; Caffeic Acids; Endothelium; Inflammation; Male; Oxidative Stress; Phenylethyl Alcohol; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley | 2020 |
Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Caffeic Acids; Computational Biology; Computer Simulation; Dimerization; ErbB Receptors; Erlotinib Hydrochloride; Exons; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Indolizines; Ligands; Lung Neoplasms; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Phenylethyl Alcohol; Quinazolines; Withanolides | 2021 |
Interaction between caffeic acid/caffeic acid phenethyl ester and micellar casein.
Topics: Antioxidants; Caffeic Acids; Caseins; Hydrophobic and Hydrophilic Interactions; Micelles; Phenylethyl Alcohol; Protein Binding; Protein Structure, Secondary; Solubility | 2021 |
Chemoenzymatic semisynthesis of caffeic acid β-phenethyl ester, an antioxidative component in propolis, from raw coffee bean extract.
Topics: Antioxidants; Caffeic Acids; Coffea; Esterification; Phenylethyl Alcohol; Plant Extracts; Propolis | 2021 |
Antioxidant effect of caffeic acid phenethyl ester in experimentally induced periodontitis.
Topics: Animals; Antioxidants; Caffeic Acids; Oxidative Stress; Periodontitis; Phenylethyl Alcohol; Rats | 2021 |
IL-8 as a Potential Therapeutic Target for Periodontitis and Its Inhibition by Caffeic Acid Phenethyl Ester In Vitro.
Topics: Anti-Inflammatory Agents; Caffeic Acids; Cytokines; Heme Oxygenase-1; Humans; I-kappa B Proteins; Inflammation; Interleukin-8; Lipopolysaccharides; NF-kappa B; NF-KappaB Inhibitor alpha; Periodontitis; Phenylethyl Alcohol; Phosphorylation; Saliva; THP-1 Cells | 2021 |
Investigation of potential inhibitor properties of ethanolic propolis extracts against ACE-II receptors for COVID-19 treatment by molecular docking study.
Topics: Angiotensin-Converting Enzyme 2; Animals; Bees; Caffeic Acids; COVID-19 Drug Treatment; Flavanones; Flavonoids; Hesperidin; Humans; Luteolin; Molecular Docking Simulation; Phenylethyl Alcohol; Plant Extracts; Propolis; Quercetin; Rutin | 2021 |
Lycopene and Caffeic Acid Phenethyl Ester Affect Caspase-3 Activity, but Do Not Alter the NO Pathway in Lung Tissue Damage Induced by Cisplatin.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Caffeic Acids; Caspase 3; Cisplatin; Lipid Peroxidation; Lung; Lycopene; Male; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Reactive Oxygen Species | 2021 |
Analysis of the Effect of N555 Mutations on the Product Specificity of Dextransucrase Using Caffeic Acid Phenethyl Ester as an Acceptor Substrate.
Topics: Caffeic Acids; Glucosyltransferases; Mutation; Phenylethyl Alcohol | 2021 |
Neuroprotective Potential of Caffeic Acid Phenethyl Ester (CAPE) in CNS Disorders: Mechanistic and Therapeutic Insights.
Topics: Aged; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Humans; Phenylethyl Alcohol | 2021 |
Icariin, Formononetin and Caffeic Acid Phenethyl Ester Inhibit Feline Calicivirus Replication In Vitro.
Topics: Animals; Antiviral Agents; Caffeic Acids; Caliciviridae Infections; Calicivirus, Feline; Cat Diseases; Cats; Cell Line; Cell Survival; Drug Interactions; Flavonoids; Isoflavones; Phenylethyl Alcohol; Virus Replication | 2021 |
Caffeic Acid Phenethyl Ester-Incorporated Radio-Sensitive Nanoparticles of Phenylboronic Acid Pinacol Ester-Conjugated Hyaluronic Acid for Application in Radioprotection.
Topics: Animals; Boronic Acids; Caffeic Acids; Cell Line; Cell Survival; Drug Liberation; Glycols; Hyaluronic Acid; Hydrogen Peroxide; Liver; Mice, Inbred BALB C; Nanoparticles; Particle Size; Phenylethyl Alcohol; Proton Magnetic Resonance Spectroscopy; Radiation Protection; Spectroscopy, Fourier Transform Infrared | 2021 |
Low concentrations of caffeic acid phenethyl ester stimulate osteogenesis in vitro.
Topics: Alkaline Phosphatase; Bone Matrix; Caffeic Acids; Calcification, Physiologic; Cell Line; Cell Survival; Core Binding Factor Alpha 1 Subunit; Gene Expression Regulation; Humans; Osteocalcin; Osteogenesis; Osteopontin; Phenylethyl Alcohol | 2021 |
Caffeic Acid Phenethyl Ester Loaded Electrospun Nanofibers for Wound Dressing Application.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bandages; Caffeic Acids; Humans; Nanofibers; Phenylethyl Alcohol; Pseudomonas aeruginosa; Staphylococcus aureus | 2022 |
CAPE-pNO
Topics: Alzheimer Disease; Animals; Animals, Outbred Strains; Autophagy; Brain Injuries; Caffeic Acids; Cell Line; Diabetes Mellitus, Experimental; Inflammation; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol | 2021 |
Investigation of the anti-inflammatory effects of caffeic acid phenethyl ester in a model of λ-Carrageenan-induced paw edema in rats.
Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Carrageenan; Disease Models, Animal; Edema; Male; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2021 |
Caffeic acid phenethyl ester mitigates infertility: A crucial role of metalloproteinase and angiogenic factor in cadmium-induced testicular damage.
Topics: Animals; Apoptosis; Cadmium; Caffeic Acids; Infertility, Male; Male; Matrix Metalloproteinase 3; Mice; Phenylethyl Alcohol; Spermatogenesis; Testis; Vascular Endothelial Growth Factor A | 2022 |
Anti-tumour potential and selectivity of caffeic acid phenethyl ester in osteosarcoma cells.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Mice; Osteosarcoma; Phenylethyl Alcohol | 2022 |
Caffeic acid phenethyl ester protects against doxorubicin-induced cardiotoxicity and increases chemotherapeutic efficacy by regulating the unfolded protein response.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Caffeic Acids; Cardiotoxins; Cell Line, Tumor; Doxorubicin; Endoplasmic Reticulum Stress; Female; Mice; Mice, Inbred BALB C; Phenylethyl Alcohol; Propolis; Protective Agents; Rats; Unfolded Protein Response | 2022 |
Caffeic acid phenethyl ester targets ubiquitin-specific protease 8 and synergizes with cisplatin in endometrioid ovarian carcinoma cells.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Cisplatin; Drug Delivery Systems; Endopeptidases; Endosomal Sorting Complexes Required for Transport; Female; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Phenylethyl Alcohol; Ubiquitin Thiolesterase; Xenograft Model Antitumor Assays | 2022 |
Caffeic acid phenethyl ester induces radiosensitization via inhibition of DNA damage repair in androgen-independent prostate cancer cells.
Topics: Androgens; Apoptosis; Caffeic Acids; Cell Line, Tumor; DNA Damage; DNA Repair; Humans; Male; Phenylethyl Alcohol; Prostatic Neoplasms | 2022 |
Effects of low dose doxycycline and caffeic acid phenethyl ester on sclerostin and bone morphogenic protein-2 expressions in experimental periodontitis.
Topics: Animals; Caffeic Acids; Doxycycline; Male; Periodontitis; Phenylethyl Alcohol; Rats | 2022 |
Combination treatment of docetaxel with caffeic acid phenethyl ester suppresses the survival and the proliferation of docetaxel-resistant prostate cancer cells via induction of apoptosis and metabolism interference.
Topics: Androgen Antagonists; Animals; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Docetaxel; Humans; Male; Mice; Mice, Nude; Phenylethyl Alcohol; Prostatic Neoplasms; Quality of Life | 2022 |
Antiradical properties of curcumin, caffeic acid phenethyl ester, and chicoric acid: a DFT study.
Topics: Caffeic Acids; Curcumin; Phenylethyl Alcohol; Succinates | 2022 |
Design and synthesis of novel caffeic acid phenethyl ester (CAPE) derivatives and their biological activity studies in glioblastoma multiforme (GBM) cancer cell lines.
Topics: Caffeic Acids; Cell Line; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Molecular Docking Simulation; Phenylethyl Alcohol | 2022 |
Interaction between caffeic acid phenethyl ester and protease: monitoring by spectroscopic and molecular docking approaches.
Topics: Caffeic Acids; Molecular Docking Simulation; Pepsin A; Peptide Hydrolases; Phenylethyl Alcohol; Spectrometry, Fluorescence; Trypsin | 2022 |
In Vitro Antimicrobial Potential of CAPE and Caffeamide Derivatives against Oral Microbes.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Caffeic Acids; Methicillin-Resistant Staphylococcus aureus; Phenylethyl Alcohol | 2022 |
Caffeic acid phenethyl ester alleviated hypouricemia in hyperuricemic mice through inhibiting XOD and up-regulating OAT3.
Topics: Animals; Caffeic Acids; Hyperuricemia; Kidney; Mice; Molecular Docking Simulation; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Oxonic Acid; Phenylethyl Alcohol; RNA, Messenger; Uric Acid; Xanthine Oxidase | 2022 |
Caffeic acid phenethyl ester inhibits pseudo-allergic reactions via inhibition of MRGPRX2/MrgprB2-dependent mast cell degranulation.
Topics: Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Caffeic Acids; Cell Degranulation; Humans; Hypersensitivity; Mast Cells; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Nerve Tissue Proteins; p-Methoxy-N-methylphenethylamine; Phenylethyl Alcohol; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Secretagogues | 2022 |
Caffeic acid phenethyl ester ameliorates imidacloprid-induced acute toxicity in the rat cerebral cortex.
Topics: Animals; Antioxidants; Caffeic Acids; Cerebral Cortex; Oxidative Stress; Phenylethyl Alcohol; Rats | 2022 |
Caffeic acid phenethyl ester loaded in a targeted delivery system based on a solid-in-oil-in-water multilayer emulsion: Characterization, stability, and fate of the emulsion during in vivo digestion.
Topics: Antioxidants; Caffeic Acids; Caseins; Cholates; Coconut Oil; Digestion; Emulsions; Lecithins; Phenylethyl Alcohol; Sodium; Water | 2022 |
Co-assembling nanoparticles of Asiatic acid and Caffeic acid phenethyl ester: Characterization, stability and bioactivity in vitro.
Topics: Caffeic Acids; Nanoparticles; Phenylethyl Alcohol; Water | 2023 |
Inhibition of focal adhesion kinase/paxillin axis by caffeic acid phenethyl ester restrains aggressive behaviors of head and neck squamous cell carcinoma in vitro.
Topics: Cadherins; Caffeic Acids; Cell Line, Tumor; Cell Movement; Focal Adhesion Protein-Tyrosine Kinases; Head and Neck Neoplasms; Humans; Paxillin; Phenylethyl Alcohol; Squamous Cell Carcinoma of Head and Neck | 2023 |
Computational and experimental evidence of the anti-COVID-19 potential of honeybee propolis ingredients, caffeic acid phenethyl ester and artepillin c.
Topics: Animals; Bees; Caffeic Acids; Phenylethyl Alcohol; Propolis | 2023 |
Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE-19 Cells.
Topics: Antioxidants; Apoptosis; Caffeic Acids; Humans; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species | 2023 |
Phosphorylated walnut protein/chitosan nanocomplexes as promising carriers for encapsulation of caffeic acid phenethyl ester.
Topics: Caffeic Acids; Chitosan; Juglans; Phenylethyl Alcohol | 2023 |
Effects of Temperature, Metal Ions and Biosurfactants on Interaction Mechanism between Caffeic Acid Phenethyl Ester and Hemoglobin.
Topics: Caffeic Acids; Hemoglobins; Molecular Docking Simulation; Phenylethyl Alcohol; Temperature | 2023 |
Investigation into Propolis Components Responsible for Inducing Skin Allergy: Air Oxidation of Caffeic Acid and Its Esters Contribute to Hapten Formation.
Topics: Cysteine; Esters; Haptens; Humans; Hypersensitivity; Phenylethyl Alcohol; Propolis | 2023 |
Caffeic acid phenethyl ester suppresses EGFR/FAK/Akt signaling, migration, and tumor growth of prostate cancer cells.
Topics: Animals; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Humans; Male; Mice; Mice, Nude; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt | 2023 |
Intralipid and caffeic acid phenethyl ester reverse the neurotoxic effects of organophosphate poisoning in rats.
Topics: Animals; Antioxidants; Caffeic Acids; Organophosphate Poisoning; Organophosphates; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar | 2023 |
Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells by inactivating FGFR1 via MD2.
Topics: Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Female; Humans; Phenylethyl Alcohol; Receptor, Fibroblast Growth Factor, Type 1 | 2023 |
Caffeic Acid Phenethyl Ester (CAPE) Synergistically Enhances Paclitaxel Activity in Ovarian Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Female; Humans; Ovarian Neoplasms; Paclitaxel; Phenylethyl Alcohol | 2023 |