Page last updated: 2024-09-02

caffeic acid phenethyl ester and phenylethyl alcohol

caffeic acid phenethyl ester has been researched along with phenylethyl alcohol in 730 studies

Compound Research Comparison

Studies
(caffeic acid phenethyl ester)
Trials
(caffeic acid phenethyl ester)
Recent Studies (post-2010)
(caffeic acid phenethyl ester)
Studies
(phenylethyl alcohol)
Trials
(phenylethyl alcohol)
Recent Studies (post-2010) (phenylethyl alcohol)
84014692,696631,615

Research

Studies (730)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.14)18.7374
1990's24 (3.29)18.2507
2000's257 (35.21)29.6817
2010's366 (50.14)24.3611
2020's82 (11.23)2.80

Authors

AuthorsStudies
Choi, HJ; Chung, TW; Ha, KT; Jeong, HS; Kim, CH; Lee, JY1
Fisher, PB; Grunberger, D; Guarini, L; Lin, J; Su, ZZ; Zucker, S1
Fisher, PB; Grunberger, D; Su, ZZ1
Banerjee, R; Caldwell, M; Efros, L; Eisinger, K; Estevez, V; Grunberger, D; Nakanishi, K; Oltz, EM1
Burke, TR; Carothers, AM; Driscoll, J; Fesen, MR; Grunberger, D; Kohn, K; Mazumder, A; Pommier, Y; Wang, J1
Fisher, PB; Grunberger, D; Lin, J; Su, ZZ1
Fesen, MR; Hiroguchi, S; Kohn, KW; Leteurtre, F; Pommier, Y; Yung, J1
Korshunova, GA; Mirzoeva, OK; Pushkareva, MA; Sud'ina, GF; Sumbatian, NV; Varfolomeev, SD1
Barrett, JC; Carothers, AM; Chiao, C; Grunberger, D; Preston, GA; Solomon, G1
Bhimani, R; Conney, AH; Ferraro, T; Frenkel, K; Grunberger, D; Huang, MT; Wei, H; Ye, J; Zadunaisky, JA1
Korshunova, GA; Mirzoeva, OK; Pushkareva, MA; Sud'ina, GF; Sumbatyan, NV; Varfolomeev, SD1
Bhimani, RS; Frenkel, K; Grunberger, D; Troll, W1
Conney, AH; Frenkel, K; Grunberger, D; Han, J; Huang, MT; Ma, W; Xie, JG; Yen, P1
Aggarwal, BB; Burke, TR; Grunberger, D; Natarajan, K; Singh, S1
Grunberger, D; Prystowsky, JH; Xue, GZ; Zheng, ZS1
Calder, PC; Knox, KA; Mirzoeva, OK; Yaqoob, P1
Chen, JH; Chin, CK; Ho, CT; Huang, MT; Shao, Y1
Carothers, AM; Grunberger, D; Jaiswal, AK; Mucha, J; Venugopal, R1
Calder, PC; Mirzoeva, OK1
Chen, J; Hong, H; Mazumder, A; Milne, GW; Neamati, N; Nicklaus, MC; Pommier, Y; Sunder, S1
Burke, TR; Mazumder, A; Neamati, N; Pommier, Y; Sunder, S; Zhao, H1
Bouillon, R; Courtois, SJ; Degreef, H; Garmyn, M; Segaert, S1
Carothers, AM; Dannenberg, AJ; Grunberger, D; Koboldt, C; Masferrer, JL; Mestre, JR; Michaluart, P; Sacks, PG; Subbaramaiah, K; Tanabe, T; Zweifel, BS1
Akyol, O; Aydin, E; Aydinç, M; Gültek, A; Gürsoy, MH; Karaman, A; Koltuksuz, U; Ozen, S; Uz, E1
Farrow, S; Holloway, KA; Howells, L; Kaptein, A; Manson, MM; Munks, RJ; Plummer, SM1
Akyol, O; Ciralik, H; Ilhan, A; Koltuksuz, U; Ozen, S; Uz, E1
Dworniczak, S; Pogorzelska, T; Rajca, M; Scheller, S; Shani, J1
Burke, TR; Chrousos, GP; Mitsiades, N; Orban, Z; Tsokos, M1
Bertagnolli, ME; Bertagnolli, MM; Carothers, AM; Weyant, MJ1
Chen, WK; Lee, YJ; Liao, PH; Yang, CY1
Chang, CC; Grunberger, D; Kang, KS; Na, HK; Trosko, JE; Wilson, MR1
Li, D; Mehta, JL; Romeo, F; Saldeen, T1
Lewis, BA; Lobkowsky, EB; Son, S1
Akyol, O; Irmak, MK; Karaman, A; Koltuksuz, U; Ozyurt, H; Uz, E; Var, A1
Chen, YJ; Shiao, MS; Wang, SY1
Dong, Z; Kaji, A; Ma, W; Miyamoto, K; Nomura, M1
Akyol, O; Irmak, MK; Karaman, A; Koltuksuz, U; Kutlu, NO; Ozyurt, H; Yağmurca, M1
Hishikawa, K; Nakaki, T1
Akyol, O; Aydin, NE; Cetin, S; Gürbüz, N; Karaman, A; Koltuksuz, U; Kutlu, R; Mutuş, HM; Ozyurt, H1
Bagnara, GP; Bonsi, L; Fiorentini, D; Hakim, G; Landi, L; Maraldi, T1
Huleihel, M; Ishano, V1
Chen, YJ; Hsu, ML; Shiao, MS; Tsai, TH; Wang, SY1
Fitzpatrick, LR; Le, T; Wang, J1
Hur, GM; Jin, C; Kim, YM; Lee, JY; Lee, YS; Park, EH; Ryu, YS; Song, YS1
Akyol, O; Irmak, MK; Ozyurt, H; Söğüt, S1
Aydin, E; Borazan, M; Cekiç, O; Cihan Dağloğlu, M; Dağlioğlu, K; Gültek, A; Totan, Y1
Calabrese, V; Foresti, R; Giuffrida Stella, AM; Green, CJ; Motterlini, R; Scapagnini, G1
Fahlman, CS; Haddad, JJ1
Borrelli, F; Capasso, F; Ialenti, A; Ianaro, A; Maffia, P; Pinto, A; Pisano, B1
Banskota, AH; Kadota, S; Matsushige, K; Midorikawa, K; Tezuka, Y; Usia, T1
Banskota, AH; Kadota, S; Nagaoka, T; Saiki, I; Tezuka, Y1
Bozaran, M; Doganay, S; Er, H; Evereklioglu, C; Ozerol, E; Turkoz, Y1
Chen, F; Huang, C; Lu, B; Medan, D; Rojanasakul, Y; Shi, X; Toledo, D; Wang, L1
Jin, C; Jung, KJ; Park, EH; Song, YS1
Akyol, O; Güleç, M; Ozyurt, H; Sahin, S; Söğüt, S; Uz, E; Var, A1
Borrelli, F; Ligresti, A; Longo, R; Rossi, A; Russo, A; Sautebin, L1
Ayan, I; Bora, A; Elmali, N; Germen, B; Mizrak, B; Türköz, Y1
Longo, R; Russo, A; Vanella, A1
Borrelli, F; Longo, R; Rossi, A; Russo, A; Sautebin, L1
Borrelli, F; Capasso, F; Di Carlo, G; Izzo, AA; Maffia, P; Maiello, FM; Mascolo, N; Russo, A1
Ceschel, GC; Lombardi Borgia, S; Maffei, P; Ronchi, C; Sforzini, A; Yasin, A1
Borrelli, F; Capasso, F; Ialenti, A; Ianaro, A; Maffia, P; Pinto, L; Russo, A1
Buhay, S; Helwer, G; Litchie, B; Thomas, S; Werner, JP; Zahradka, P1
Alam, J; Balogun, E; Foresti, R; Gong, P; Green, CJ; Hoque, M; Killeen, E; Motterlini, R1
Banskota, AH; Kadota, S; Matsushige, K; Midorikawa, K; Nagaoka, T; Tezuka, Y1
Krings, G; Lopes-Virella, MF; Vielma, SA1
Borrelli, F; Capasso, R; Cicala, C; Iorio, C; Mascolo, N; Morello, S1
Banskota, AH; Harimaya, Y; Kadota, S; Koizumi, K; Nagaoka, T; Saiki, I; Tezuka, Y1
Liang, CL; Pan, XH; Pang, RQ; Zhao, B; Zhao, J; Zhao, WX1
Borrelli, F; Cardile, V; Gentile, B; Panico, A; Russo, A1
Bockaert, J; Briant, L; Courseau, AS; de Bock, F; Lerner-Natoli, M; Montpied, P; Niel, G; Rondouin, G1
Calikoglu, I; Calikoglu, M; Coskun, B; Ercan, B; Gul, A; Kanik, A; Sucu, N; Tamer, L1
Erdogan, H; Fadillioglu, E; Gozukara, ME; Gulec, M; Irmak, MK; Ozer, M; Sogut, S; Yagmurca, M1
Huuskonen, J; Kyrylenko, S; Pihlaja, R; Salminen, A; Suuronen, T1
Amodio, R; Cacchio, M; De Ruvo, C; Di Matteo, V; Di Santo, A; Esposito, E; Lorenzet, R; Martelli, N; Poggi, A; Rotilio, D; Sacchetti, A1
Calzado, MA; Fiebich, BL; Macho, A; Márquez, N; Muñoz, E; Sancho, R1
Hishikawa, K; Nakaki, T; Shimizu, N; Takayanagi, A; Watabe, M1
Chu, CY; Kuo, HC; Lee, YJ; Lin, WC; Tseng, TH; Wang, CJ1
Chen, CN; Lin, JK; Wu, CL2
Blijlevens, NM; de Witte, TJ; Donnelly, JP; M'Rabet, L; Marteijn, J; Timal, S; van't Land, B1
Akyol, O; Armutcu, F; Gulec, M; Gurel, A; Kutlu, NO; Ozyurt, H; Sahin, S; Sogut, S1
Akyol, O; Armutçu, F; Iraz, M; Kart, L; Ozen, S; Ozyurt, H; Söğüt, S; Temel, I; Uzun, A; Yildirim, Z1
Chen, YJ; Chen, YY; Hsu, ML; Liao, HF; Liao, HJ; Liu, JJ; Shiao, MS; Shieh, CJ; Shieh, HJ1
Hitsuda, Y; Igishi, T; Kodani, M; Matsumoto, S; Nakanishi, H; Shigeoka, Y; Shimizu, E; Yasuda, K1
Arce-Popoca, E; Carrasco-Legleu, CE; Fattel-Fazenda, S; Márquez-Rosado, L; Pérez-Carreón, JI; Villa-Treviño, S1
Douglas, SD; Guo, CJ; Ho, WZ; Li, Y; Qi, XX; Song, L; Zhang, T1
Clarençon, D; Linard, C; Marquette, C; Mathé, D; Mathieu, J; Pennequin, A1
Armutcu, F; Babucçu, O; Gürel, A; Hoşnuter, M; Işikdemir, A; Kargi, E1
Chung, KS; Hoe, KL; Jang, YJ; Kim, DU; Maeng, PJ; Oh, GT; Park, SK; Ryoo, SW; Won, M; Yoo, HS1
Chung, SJ; Chung, ST; Eom, JH; Kim, HS; Kim, KA; Lee, JK; Oh, HY; Paik, SY; Park, JH1
Huang, MH; Lin, MW; Wu, SN; Yang, SR1
Brudzynski, K; Carlone, R1
Borazan, M; Cigremis, Y; Er, H; Mizrak, B; Parlakpinar, H; Turkoz, Y; Yilmaz, H1
Akyol, O; Armutcu, F; Gurel, A; Ilhan, A; Iraz, M; Oztas, E1
Coffey, R; Fitzpatrick, JM; McEleny, K; Morrissey, C; Watson, RW1
Acet, A; Ozer, MK; Parlakpinar, H1
Chen, MF; Chen, WC; Chen, YJ; Keng, PC; Wu, CT1
Akyol, O; Gulec, M; Iraz, M; Kalcioglu, MT; Kizilay, A; Ozerol, E; Ozturan, O1
Del Boccio, P; Rotilio, D1
Colakoglu, N; Kus, I; Ogeturk, M; Pekmez, H; Sarsilmaz, M; Seckin, D1
Aktaş, S; Calikoğlu, I; Calikoğlu, M; Sucu, N; Tamer, L; Unlü, A1
Celli, N; Dragani, LK; Mariani, B; Murzilli, S; Rossi, C; Rotilio, D1
Erdogan, H; Fadillioglu, E; Iraz, M; Songur, A; Ucar, M; Yagmurca, M1
Farrar, WL; Hodge, DR; Wang, L; Xiao, W; Yang, X; Zhang, X1
Douglas, SD; Gao, Z; Grinspan, J; Guo, CJ; Ho, WZ; Lai, JP; Riedel, E; Wolf, BA1
Altuntas, I; Ozcelik, N; Uz, E; Yilmaz, HR; Yucel, N1
Dodel, RC; Du, Y; Farlow, MR; Hampel, H; Holtzman, DM; Ma, Z; Oertel, W; Wei, X; Yan, C; Zhao, L1
Atmaca, G; Aydogdu, N; Batcioglu, K; Kaymak, K; Yalcin, O1
Fujita, T; Hishikawa, K; Nakaki, T1
Chang, YC; Cho, G; Chung, TW; Kim, CH; Kim, JG; Kim, SH; Ko, JH; Lee, YC; Moon, SK1
Foresti, R; Green, CJ; Hoque, M; Monti, D; Motterlini, R1
Celik, O; Cigremis, Y; Hascalik, M; Hascalik, S; Mizrak, B; Turkoz, Y; Yologlu, S1
Altinyazar, C; Armutcu, F; Gurel, A; Hosnuter, M; Kargi, E; Unalacak, M1
Acet, A; Bay-Karabulut, A; Parlakpinar, H; Polat, A; Tasdemir, S; Ucar, M; Vardi, N1
Okutan, H; Ozcelik, N; Uz, E; Yilmaz, HR1
Chun, KS; Kang, KS; Lee, HJ; Lee, JS; Lee, KW; Surh, YJ1
Akyol, O; Armutcu, F; Gurel, A; Ilhan, A; Iraz, M1
Al-Anati, L; Katz, N; Petzinger, E1
Colakoglu, N; Ilhan, N; Kus, I; Ogeturk, M; Sarsilmaz, M; Zararsiz, I1
Fujita, T; Iwai, K; Kakino, Y; Kishimoto, N1
Acet, A; Mizrak, B; Parlakpinar, H; Polat, A; Sahna, E1
Nishioka, N; Tsuji, T; Yoshizumi, K1
Acet, A; Ozturk, F; Parlakpinar, H; Vardi, N1
Shi, XY; Shieh, DB; Wu, SN; Wu, YN; Yang, SR1
Armagan, A; Caliskan, S; Koylu, H; Koyu, A; Ozguner, F1
Chou, FP; Kuo, HC; Kuo, WH; Lee, YJ; Lin, WL; Tseng, TH1
Chang, KW; Chen, CF; Don, MJ; Ho, LK; Hung, PS; Lee, YT; Lo, YS; Shen, YC1
Ayaz, L; Aytacoglu, B; Bayri, O; Dikmengil, M; Döndaş, A; Ozeren, M; Sucu, N; Tamer, L1
Acet, A; Eşrefoğlu, M; Gül, M; Parlakpinar, H1
Mayhan, WG; Miller, DW; Trickler, WJ1
Cinel, L; Degirmenci, U; Ercil, M; Kanik, A; Koksel, O; Ozdulger, A; Tamer, L; Unlu, S1
Bianchi, R; Bonomini, F; Buffoli, B; Giugno, L; Rezzani, R1
Awale, S; Kadota, S; Matsushige, K; Shrestha, SP; Tezuka, Y; Ueda, JY1
Isik, B; Ozugurlu, F; Ozyurt, B; Ozyurt, H; Sahin, S; Sogut, S; Uz, E; Yilmaz, HR1
Acet, A; Cigremis, Y; Ozer, MK; Parlakpinar, H; Ucar, M; Vardi, N2
Chen, CS; Chen, FL; Chou, MY; Ho, CC; Hu, CC; Lin, SS; Lu, GY; Yang, CC1
Chung, KH; Chung, TW; Gu, YH; Jin, UH; Kang, SK; Kim, CH; Kim, JK; Suh, SJ; Suzuki, I1
Bastürk, M; Cinel, L; Degirmenci, U; Kanik, A; Kaplan, MB; Koksel, O; Ozdulger, A; Tamer, L1
Daniel, BM; DeCoster, MA; Wang, G1
Eckard, J; Frenkel, K; Huang, X; Rossman, TG; Wu, J; Yang, C; Yusuf, R; Zhang, P; Zhang, R1
Chen, YC; Chih, CL; Huang, SS; Liao, PH; Lin, RH; Lin, SM; Liu, SM; Tsai, SK1
Armagan, A; Demirel, R; Koyu, A; Oktem, F; Ozguner, F; Uz, E; Vural, H; Yilmaz, R1
Ayata, A; Koyu, A; Oktem, F; Ozguner, F; Yilmaz, HR1
Akturk, O; Altuntas, I; Oktem, F; Olgar, S; Ozguner, F; Sulak, O; Yilmaz, HR1
Oktem, F; Ozgüner, F; Uz, E; Uzar, E; Yilmaz, HR1
Atik, U; Cinel, L; Değirmenci, U; Kanik, A; Oz, O; Tamer, L; Vatansever, H; Yildirim, O; Yilmaz, A1
Chiou, SH; Chiu, JH; Lin, YH; Tseng, WS; Wong, TT; Yen, SH1
Ascione, V; Aviello, G; Borrelli, F; Capasso, F; Capasso, R; Posadas, I1
Crippen, TL1
Chung, HJ; Hong, JY; Hwang, HJ; Lee, SK; Min, HY; Park, EJ; Park, HJ1
Du, R; Du, Y; Farlow, MR; Han, L; Hou, D; Johnstone, BH; Ma, Z; Tan, J; Wei, X; Zhao, L1
Abdel-Latif, MM; Homasany, BS; Kelleher, D; Sabra, K; Windle, HJ1
Chen, YJ; Liao, HF; Shiao, MS; Tsai, TH; Wang, SY1
Akyol, O; Bagci, C; Cagli, K; Cavdar, S; Cengiz, B; Dinckan, H; Gulec, M; Pence, S; Sari, I1
Min, TS; Park, SH1
Chih, CL; Huang, SS; Liao, PH; Lin, MJ; Lin, RH; Lin, SM; Liu, SM; Tsai, SK; Yang, CY1
Bardak, Y; Comlekci, S; Ozguner, F1
Bas, O; Kilbas, S; Koyuncuoglu, HR; Kucuker, H; Sahin, O; Songur, A; Uz, E; Uzar, E; Yilmaz, HR; Yurekli, VA1
Chen, MF; Chen, WC; Keng, PC; Liao, SK; Lin, PY; Yang, CT1
Altinbas, A; Cesur, G; Dogan, A; Kisioglu, AN; Ozaydin, M; Ozguner, F; Vural, H; Yildirim, NG1
Erdogan, S; Fadillioglu, E; Iraz, M; Tasdemir, S1
Akpolat, N; Aladag, MA; Cigremis, Y; Ozcan, C; Parlakpinar, H; Sahna, E; Turkoz, Y1
Chen, H; Costa, M; Eckard, J; Frenkel, K; Huang, X; Wu, J1
Basić, I; Orsolić, N; Saranović, AB1
Altuntas, I; Eren, I; Malas, MA; Ramazan Yilmaz, H; Sahin, O; Songur, A; Sulak, O; Uz, E; Yavuz, Y1
Kus, I; Ozyurt, B; Ozyurt, H; Parlaktas, BS; Pekmez, H; Sarsilmaz, M1
Akyol, A; Alver, A; Beşir, A; Cay, A; Ertürk, E; Imamoğlu, M; Koşucu, M; Ozen, I; Ulusoy, H; Yuluğ, E1
Alaybeyoglu, N; Bilen, BT; Celik, M; Gültek, A; Iraz, M; Kilinç, H; Sezgin, N1
Bowman, PD; Kerwin, SM; Stavchansky, S; Wang, X3
Akyol, O; Bagci, C; Gulec, M; Ince, H; Kandemir, E1
Ates, B; Dogru, AK; Dogru, MI; Erdogan, A; Esrefoglu, M; Gul, M; Yilmaz, I; Yurekli, M1
Dodel, R; Du, Y; Fontanilla, C; Hampel, H; Ma, Z; Noelker, C; Wei, X1
Gultekin, F; Kilbas, S; Koyuncuoglu, HR; Kutluhan, S; Uz, E; Uzar, E; Yilmaz, HR1
Chiechio, S; Copani, A; De Petris, L; Gereau, RW; Morales, ME; Nicoletti, F1
Kuo, HC; Kuo, WH; Lee, YJ; Tseng, TH; Wang, CJ1
Iraz, M; Koca, K; Ozyurt, B; Ozyurt, H; Sahin, S1
Buyukbas, S; Cabuk, M; Kanter, M; Ocakci, A1
Lee, YJ; Tseng, TH1
Mitchell, BF; Olson, DM; Wilson, RR; Zaragoza, DB1
Atik, E; Görür, S; Kiper, AN1
Cheng, KS; Li, CL; Lin, MW; Ting, WH; Wu, AZ; Wu, SN1
Ayata, A; Oktem, F; Olgar, S; Ozguner, F; Uz, E; Uzare, E; Yilmaz, HR1
He, Y; Li, Z; Wang, D; Xiang, D; Xie, J; Zhong, Z1
Fu, T; He, YH; He, YJ; Liu, BH; Qiao, ZY; Xiang, DB1
Benderitter, M; Grémy, O; Linard, C1
Cicek, E; Demirin, H; Gokalp, O; Gokcimen, A; Kocak, A; Koyu, A; Mollaoglu, H; Oktem, F; Ozguner, F1
Chang, CM; Juang, SJ; Lai, LP; Leu, JG; Liang, YJ; Shyu, KG; Wang, BW1
Altunbas, A; Cicek, E; Gokalp, O; Ozcelik, N; Ozer, MK; Uz, E; Yilmaz, HR1
Arimura, K; Higashimoto, I; Matsuyama, W; Mitsuyama, H; Ono, M; Osame, M; Shirahama, Y1
Cerci, C; Cerci, SS; Cicek, E; Koyu, A; Oral, B; Yildiz, M1
Aladag, M; Ara, C; Ay, S; Esrefoglu, M; Gul, M; Isik, B; Polat, A; Tekerleklioglu, MS; Yilmaz, S1
Aslantas, O; Celik, S; Erdogan, S; Gorur, S; Hakverdi, S; Ocak, S1
Bhattacharyya, S; Borthakur, A; Dudeja, PK; Tobacman, JK1
Arce-Popoca, E; Carrasco-Legleu, CE; Fattel-Fazenda, S; Hernández-García, S; Márquez-Rosado, L; Sánchez-Pérez, Y; Villa-Treviño, S1
Aytacoglu, BN; Bayindir, I; Coskun, B; Dikmengil, M; Ersoz, G; Kose, N; Oguz, I; Ozeren, M; Sucu, N; Tamer, L1
Aslan, H; Atis, O; Ekici, F; Ozyurt, B; Ozyurt, H; Parlaktas, BS1
Dillman, JF; Minsavage, GD1
Abdel Gawad, HS; El-Bab, MF; Hammad, LN; Mohamadin, AM1
Aperis, G; Ausubel, FM; Breger, J; Fuchs, BB; Moy, TI; Mylonakis, E1
Akpolat, N; Erdogan, H; Ozyurt, B; Ozyurt, H; Sarsilmaz, M1
Celli, N; Dragani, LK; Murzilli, S; Pagliani, T; Poggi, A1
Acet, A; Askar, I; Aydogan, H; Aydogan, N; Bay-Karabulut, A; Fariz, A; Gurlek, A; Parlakpinar, H1
Ansari, MA; Elango, C; Khan, M; Singh, AK; Singh, I1
Celik, S; Erdogan, S; Gorur, S; Hakverdi, S; Ocak, S1
Ikota, N; Ishihara, H; Kurematsu, A; Nakanishi, I; Suzuki, K; Tanaka, I; Yakumaru, H1
Cho, CG; Kwon, SK; Park, SW; Song, JJ1
Chou, DS; Fong, TH; Hsiao, G; Lee, JJ; Lin, KH; Shen, CH; Sheu, JR1
Güney, M; Karahan, N; Mungan, T; Nasir, S; Oral, B1
Cosar, M; Eser, O; Mollaoglu, H; Sahin, O; Sezer, M; Songur, A; Yaman, M1
Han, M; Kim, HS; Lee, ES; Lee, M; Lee, YM; Park, JM; Park, SH; Suh, PG; Uhm, KO1
Choi, C; Choi, K; Han, YH1
Fidan, F; Kara, Z; Sahin, O; Sezer, M; Solak, O; Unlu, M1
Alrefai, WA; Borthakur, A; Dudeja, PK; Gill, RK; Ramaswamy, K; Saksena, S1
Avci, CB; Aydin, HH; Gunduz, C; Oktem, G; Sahin, F; Saydam, G; Selvi, N; Topcuoglu, N1
Chen, TG; Chou, DS; Lee, JJ; Lin, KH; Shen, CH; Sheu, JR1
Choi, I; Choi, IW; Choi, YH; Jung, WK; Kang, MS; Kim, SK; Lee, DY; Lee, SW; Park, SG; Seo, SK; Yea, SS1
Ben Bassat, H; Berger, N; Klein, BY; Laskov, R1
Acosta, A; Angulo, A; Astiazaran, H; Dominguez, Z; Goycoolea, FM; Hernandez, J; Lugo, E; Navarro, M; Robles, R; Robles-Zepeda, R; Velazquez, C; Velazquez, EF1
Altuğ, E; Atik, E; Avci, G; Kontas, T; Serarslan, G1
Cecen, S; Ek, RO; Ergin, K; Kavak, T; Serter, M; Yenisey, C; Yildiz, Y1
Baek, JH; Jun, JH; Kim, GS; Kwak, HB; Lee, SH; Lee, ZH; Ryoo, HM; Seo, SB; Woo, KM1
Alhan, E; Ates, B; Ercin, C; Erdogan, S; Kaklikkaya, N; Kural Vanizor, B; Topaloglu, S; Turkyilmaz, S1
Cohen, JJ; Takizawa, BT; Uchio, EM; Weiss, RM; Wheeler, MA1
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Cantürk Tan, F; Ceylan, T; Kaymak, E; Yakan, B1
Abdik, H; Avşar Abdik, E; Sahin, F; Turan, D1
Cholewa, K; Dzik, R; Jasik, K; Kabała-Dzik, A; Kleczka, A; Kubina, R; Stojko, J1
Cao, D; Huang, CH; Huang, R; Lin, L; Mao, L; Qin, L; Shao, B; Shao, J; Sheng, ZG; Zhang, CZ; Zhang, ZQ; Zhu, BZ1
Bai, HW; Hong, CJ; Wang, P; Yamabe, N; Zhu, BT1
Gulhan, MF; Ozdemir, B; Sahna, E; Selamoglu, Z1
Ali, MA; Menze, ET; Tadros, MG; Tolba, MF1
Leible, M; Lin, J; Wang, A; Weiss, J; Zhong, Q1
da Silva, CCS; Fontes-Júnior, EA; Luz, DA; Maia, CSF; Martins, MAT; Martins, MD; Menezes da Silveira, CCS; Prediger, RDS1
Hogan, L; Kim, MJ; Lassalle-Claux, G; Luiker, K; Murugesan, A; Reiman, T; Selka, A; Touaibia, M; Vaillancourt, E1
Artaş, G; Dündar, S; Gül, M; Özcan, EC; Polat, ME; Tanık, A; Yiğin, A1
Auh, JH; Byun, S; Choi, S; Hong, S; Kim, DH; Lim, TG; Oh, J; Shin, EJ; Woo, SO1
Amorati, R; Baschieri, A; Guo, Y; Valgimigli, L1
Cao, Y; Du, Q; Jiang, Y; Jiao, X; Li, Y; Liu, X; Tang, M; Tian, C; Wang, Y; Wang, Z; Xie, P; Yang, J1
Novinec, M; Ulčakar, L1
Kapare, HS; Lohidasan, S; Mahadik, K; Sinnathambi, A1
Akil, M1
Cui, H; Liu, X; Lv, L; Ma, Z; Yang, L1
Balaha, M; Cataldi, A; De Filippis, B; di Giacomo, V1
Kaul, SC; Kumar, V; Malik, V; Sundar, D; Wadhwa, R1
Qin, J; Wa, W; Wang, Y; Yang, M; Zheng, J1
Fujita, R; Hanaya, K; Hashimoto, R; Higashibayashi, S; Iai, H; Inoue, H; Sugai, T1
Bilgici, B; Demir, E; Lütfioğlu, M; Otan Özden, F1
Anna, B; Emilia, M; Kamila, Ż; Olgierd, B1
Huang, YK; Lee, CY; Shen, MY; Tsai, PH; Tseng, KF; Wang, JS1
Belduz, AO; Guler, HI; Kolayli, S; Tatar, G; Yildiz, O1
Ilić, B; Krtinić, D; Milojković, M; Pavlović, M; Rančić, A; Rančić, M; Ristić, L; Sokolović, D; Živković, N1
Ding, XJ; Hu, XQ; Liu, LH; Yang, JW; Yu, XQ; Zhang, HB1
Kulkarni, NP; Narula, AS; Sharma, SS; Vaidya, B1
Cui, Z; Dong, H; Gong, Q; Hu, G; Huang, H; Li, D; Li, Z; Liu, T; Pei, Z; Shao, J; Tan, Y; Wang, J; Wang, K; Wang, Q; Zhang, Q; Zhang, S; Zhao, S1
Choi, SH; Jeong, YI; Kang, S; Lee, DY; Lee, HL; Lee, HY; Lee, JH; Lee, MK; Lee, SH1
de Castro Raucci, LMS; Demasi, APD; Joly, JC; Martinez, EF; Santos, PHN; Silva, HL; Teixeira, LN1
Bhargava, P; Ishida, Y; Kaul, A; Kaul, SC; Mahanta, D; Terao, K; Wadhwa, R1
Bagatini, MD; de Oliveira Maciel, SFV; de Resende E Silva, DT; do Carmo, TIT; Dos Anjos, F; Soares, VEM; Wruck, J1
Akmayan, I; Arasoglu, T; Derman, S; Egri, O; Kaya, S; Yilmaz, DE1
Han, Y; Li, B; Li, Z; Luo, Z; Wan, Q1
Gur, C; Ileriturk, M; Kandemir, FM; Kaynar, O; Semis, HS1
Abdallah, EAA; El-Refaei, MF1
Fakhoury, VS; Inacio, KK; Oliveira, GSN; Oliveira, RC; Pagnan, AL; Pessoa, AS; Sanches, MLR; Tokuhara, CK; Ximenes, VF1
Cao, Y; Cui, G; Han, H; Kong, D; Zhang, Y; Zhu, H1
Arrighetti, N; Carenini, N; Colombo, D; Corna, E; Costantino, M; D'Arcy, P; De Cesare, M; Gatti, L; Linder, S; Perego, P; Sjöstrand, L; Zuccolo, M1
Kırzıoğlu, FY; Özmen, Ö; Yiğit, U1
Chuu, CP; Fu, YK; Hour, TC; Huang, SH; Kuo, YY; Lin, CY; Tseng, JC; Wang, BJ1
Manzanilla, B; Robles, J1
Almas, F; Dogan, B; Durdagi, S; Guzel, M; Guzel, MA; Karakas, N; Koc, EB; Mirat, A; Savlug Ipek, O; Sucu, BO; Uludag, D1
Barone, E; Butterfield, DA; Caforio, M; Di Domenico, F; Folgiero, V; Locatelli, F; Pagnotta, S; Perluigi, M; Petrini, S; Pittalà, V; Salerno, L; Tramutola, A1
Chen, Y; Hao, S; Liu, J; Nai, X; Xuan, H; Zhang, Q1
Chien, CY; Chiu, KC; Hsia, SM; Kuo, YH; Li, PJ; Shieh, TM; Shih, YH; Wang, TH1
Cai, M; Chen, S; Gao, X; Hu, H; Huang, L; Li, X; Liang, D; Liu, Y; Wu, Q; Xiao, C; Xie, Y; Yong, T1
Adhikari, N; Shim, WS1
Cicek, M; Demir, M; Deresoy, FA; Eser, N; Yoldas, A1
Chen, P; Chen, X; Dai, J; Du, Y; Huang, Y; Li, R; Liu, L; Wang, L; Wang, Q; Wang, Z; Wei, X; Yang, X; Zhou, Z1
Hao, L; Li, X; Liu, K; Liu, Y; Lu, J; Shao, Y; Wang, X; Yi, J; Zhang, X1
Algburi, FS; Caglayan, C; Taysi, ME; Taysi, S1
Cho, SD; Shin, JA; Yu, HJ1
Basu, B; Ishida, Y; Kaul, A; Kaul, SC; Kumar, V; Meidinna, HN; Sari, AN; Sundar, D; Terao, K; Vrati, S; Wadhwa, R1
Barnstable, CJ; Li, X; Ren, C; Tombran-Tink, J; Yu, Z; Zhang, M; Zhang, X; Zhou, P1
Giri, PP; Khan, F; Pandey, P; Upadhyay, TK1
He, C; Huang, X; Ling, M; Xu, Y; Zhou, Z1
Chen, Y; Kong, J; Li, M; Li, Y; Liu, J; Liu, M; Nai, X; Yan, H; Zhang, Q; Zhao, Z1
Hagvall, L; Hurben, AK; Karlsson, I; Ndreu, L; Nyman, GSA; Tretyakova, NY1
Chen, JK; Chuu, CP; Hour, TC; Hsiao, PJ; Kao, CL; Kuo, LK; Kuo, YY; Shih, LJ; Tseng, JC; Wang, BJ; Wang, YP; Yeh, CC1
Basarslan, F; Basarslan, SK1
Chen, L; Ding, H; Fang, L; Fang, Q; Fu, Y; Qi, Y; Xin, W1
Dzik, R; Kabała-Dzik, A; Kleczka, A1

Reviews

30 review(s) available for caffeic acid phenethyl ester and phenylethyl alcohol

ArticleYear
[NF-kappa B as a therapeutic drug target].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2001, Volume: 118, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arteriosclerosis; Caffeic Acids; DNA-Binding Proteins; Drug Design; Flavonoids; Gene Transfer Techniques; Humans; I-kappa B Proteins; Immunosuppressive Agents; Inflammation; Mutation; Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Steroids

2001
Evaluation of natural and synthetic compounds from East Asiatic folk medicinal plants on the mediation of cancer.
    Anti-cancer agents in medicinal chemistry, 2006, Volume: 6, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Asia, Eastern; Benzofurans; Caffeic Acids; Coumarins; Flavonoids; Hibiscus; Humans; Medicine, Traditional; Mice; Phenylethyl Alcohol; Piper; Plant Preparations

2006
Cytotoxic constituents of propolis inducing anticancer effects: a review.
    The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:11

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Diterpenes; Flavonoids; Humans; Neoplasms; Phenylethyl Alcohol; Propolis

2011
The potential usage of caffeic acid phenethyl ester (CAPE) against chemotherapy-induced and radiotherapy-induced toxicity.
    Cell biochemistry and function, 2012, Volume: 30, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Neoplasms, Experimental; Phenylethyl Alcohol

2012
The immunomodulatory and anticancer properties of propolis.
    Clinical reviews in allergy & immunology, 2013, Volume: 44, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Caffeic Acids; Cell Line, Tumor; Humans; Immunologic Factors; Neoplasms; Neoplastic Stem Cells; Oncogene Proteins; Phenylethyl Alcohol; Phenylpropionates; Propolis; Signal Transduction; T-Lymphocyte Subsets; Tumor Microenvironment

2013
Development of polyphenols as HIV-1 integrase inhibitors: a summary and perspective.
    Current medicinal chemistry, 2012, Volume: 19, Issue:32

    Topics: Animals; Caffeic Acids; Drug Design; HIV Integrase Inhibitors; Humans; Phenylethyl Alcohol; Polyphenols; Structure-Activity Relationship

2012
The anticancer mechanism of caffeic acid phenethyl ester (CAPE): review of melanomas, lung and prostate cancers.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:15

    Topics: Antineoplastic Agents; Caffeic Acids; Humans; Lung Neoplasms; Male; Melanoma; Phenylethyl Alcohol; Prostatic Neoplasms

2012
In vivo and in vitro antıneoplastic actions of caffeic acid phenethyl ester (CAPE): therapeutic perspectives.
    Nutrition and cancer, 2013, Volume: 65, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Central Nervous System Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Leukemia; Phenylethyl Alcohol; Propolis

2013
Caffeic acid phenethyl ester, a promising component of propolis with a plethora of biological activities: a review on its anti-inflammatory, neuroprotective, hepatoprotective, and cardioprotective effects.
    IUBMB life, 2013, Volume: 65, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bees; Biological Availability; Caffeic Acids; Cardiotonic Agents; Liver; Neuroprotective Agents; Phenylethyl Alcohol

2013
Caffeic acid phenethyl ester and therapeutic potentials.
    BioMed research international, 2014, Volume: 2014

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Humans; Phenylethyl Alcohol; Propolis

2014
Caffeic acid phenethyl ester as a protective agent against nephrotoxicity and/or oxidative kidney damage: a detailed systematic review.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Antioxidants; Caffeic Acids; Humans; Oxidative Stress; Phenylethyl Alcohol

2014
Caffeic acid phenethyl ester: its protective role against certain major eye diseases.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2014, Volume: 30, Issue:9

    Topics: Animals; Bees; Caffeic Acids; Disease Models, Animal; Eye Diseases; Humans; NF-kappa B; Phenylethyl Alcohol; Propolis

2014
Bioactivity and chemical synthesis of caffeic acid phenethyl ester and its derivatives.
    Molecules (Basel, Switzerland), 2014, Oct-13, Volume: 19, Issue:10

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Caffeic Acids; Cell Line, Tumor; Humans; Phenylethyl Alcohol; Propolis

2014
Caffeic Acid Phenethyl Ester: A Review of Its Antioxidant Activity, Protective Effects against Ischemia-reperfusion Injury and Drug Adverse Reactions.
    Critical reviews in food science and nutrition, 2016, Oct-02, Volume: 56, Issue:13

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Caffeic Acids; Drug-Related Side Effects and Adverse Reactions; Humans; Phenylethyl Alcohol; Propolis; Reperfusion Injury

2016
Future opportunities in preventing ototoxicity: Caffeic acid phenethyl ester may be a candidate (Review).
    Molecular medicine reports, 2015, Volume: 12, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Humans; Myringosclerosis; Otitis Media; Oxidative Stress; Phenylethyl Alcohol; Propolis

2015
Caffeic Acid phenethyl ester is a potential therapeutic agent for oral cancer.
    International journal of molecular sciences, 2015, May-12, Volume: 16, Issue:5

    Topics: Animals; Caffeic Acids; Humans; Mouth Neoplasms; Phenylethyl Alcohol

2015
Melatonin and caffeic acid phenethyl ester in the regulation of mitochondrial function and apoptosis: The basis for future medical approaches.
    Life sciences, 2016, Mar-01, Volume: 148

    Topics: Animals; Apoptosis; Caffeic Acids; Forecasting; Humans; Melatonin; Mitochondria; Phenylethyl Alcohol

2016
Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes.
    Current medicinal chemistry, 2018, Volume: 25, Issue:37

    Topics: Animals; Antioxidants; Caffeic Acids; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Disease Progression; Humans; Oxidative Stress; Phenylethyl Alcohol; Polyphenols

2018
Radio-Modulatory Potential of Caffeic Acid Phenethyl Ester: A Therapeutic Perspective.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:4

    Topics: Antineoplastic Agents; Caffeic Acids; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Phenylethyl Alcohol; Structure-Activity Relationship

2018
Radiation-Induced Heart Diseases: Protective Effects of Natural Products.
    Medicina (Kaunas, Lithuania), 2019, May-09, Volume: 55, Issue:5

    Topics: Biological Products; Caffeic Acids; Curcumin; Drug Combinations; Drugs, Chinese Herbal; Guaiacol; Heart Diseases; Hesperidin; Humans; Melatonin; Phenylethyl Alcohol; Protective Factors; Radiation Injuries; Selenium; Vitis

2019
Natural Product-Based Nanomedicine in Treatment of Inflammatory Bowel Disease.
    International journal of molecular sciences, 2020, May-31, Volume: 21, Issue:11

    Topics: Animals; Benzoquinones; Biological Products; Biomimetics; Caffeic Acids; Curcumin; Cytokines; Exosomes; Humans; Inflammation; Inflammatory Bowel Diseases; Insecta; Macromolecular Substances; Nanomedicine; Oxidative Stress; Phenylethyl Alcohol; Phytochemicals; Plant Extracts; Polysaccharides; Quercetin; Resveratrol; Stilbenes; Transcription Factors; Translational Research, Biomedical; Vasoactive Intestinal Peptide; Zingiber officinale

2020
Propolis: A useful agent on psychiatric and neurological disorders? A focus on CAPE and pinocembrin components.
    Medicinal research reviews, 2021, Volume: 41, Issue:2

    Topics: Animals; Bees; Caffeic Acids; Flavanones; Humans; Nervous System Diseases; Phenylethyl Alcohol; Propolis

2021
Recent progresses in the pharmacological activities of caffeic acid phenethyl ester.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Caffeic Acids; Drug Development; Humans; Neuroprotective Agents; NF-kappa B; Phenylethyl Alcohol; Propolis

2021
CAPE and Neuroprotection: A Review.
    Biomolecules, 2021, 01-28, Volume: 11, Issue:2

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents; Antifungal Agents; Antioxidants; Antiviral Agents; Apoptosis; Brain; Caffeic Acids; Humans; Inflammation; Ischemia; Neurodegenerative Diseases; Parkinson Disease; Phenylethyl Alcohol; Propolis; Psychotic Disorders; Seizures

2021
The Pluripotent Activities of Caffeic Acid Phenethyl Ester.
    Molecules (Basel, Switzerland), 2021, Mar-02, Volume: 26, Issue:5

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Caffeic Acids; Humans; Phenylethyl Alcohol

2021
Experimental Evidence for Therapeutic Potentials of Propolis.
    Nutrients, 2021, Jul-24, Volume: 13, Issue:8

    Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents; Antioxidants; Brazil; Caffeic Acids; Humans; New Zealand; Phenylethyl Alcohol; Phenylpropionates; Propolis

2021
Role of inflammation and oxidative stress in tissue damage associated with cystic fibrosis: CAPE as a future therapeutic strategy.
    Molecular and cellular biochemistry, 2022, Volume: 477, Issue:1

    Topics: Anti-Inflammatory Agents; Caffeic Acids; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Inflammation; Mutation; Oxidative Stress; Phenylethyl Alcohol

2022
CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down Syndrome.
    Free radical biology & medicine, 2022, Volume: 183

    Topics: Animals; Basic-Leucine Zipper Transcription Factors; Caffeic Acids; Down Syndrome; Humans; Kelch-Like ECH-Associated Protein 1; Mice; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol

2022
Caffeic acid phenethyl ester: A review on its pharmacological importance, and its association with free radicals, COVID-19, and radiotherapy.
    Phytotherapy research : PTR, 2023, Volume: 37, Issue:3

    Topics: Anti-Inflammatory Agents; Caffeic Acids; COVID-19; Free Radicals; Humans; Molecular Docking Simulation; Phenylethyl Alcohol; SARS-CoV-2

2023
Therapeutic efficacy of caffeic acid phenethyl ester in cancer therapy: An updated review.
    Chemical biology & drug design, 2023, Volume: 102, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Humans; Neoplasms; Phenylethyl Alcohol; Propolis

2023

Trials

1 trial(s) available for caffeic acid phenethyl ester and phenylethyl alcohol

ArticleYear
Nanoleakage inhibition within hybrid layer using new protective chemicals and their effect on adhesion.
    Journal of dental research, 2011, Volume: 90, Issue:1

    Topics: Acrylates; Acrylic Resins; Bisphenol A-Glycidyl Methacrylate; Boron Compounds; Caffeic Acids; Cementation; Dental Bonding; Dental Cements; Dental Leakage; Dental Porcelain; Dentin; Dentin-Bonding Agents; Enzyme Inhibitors; Fluorides; Humans; Materials Testing; Methacrylates; Methylmethacrylate; Methylmethacrylates; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Phenylethyl Alcohol; Resin Cements; Silver Staining; Stress, Mechanical; Tensile Strength; Titanium

2011

Other Studies

699 other study(ies) available for caffeic acid phenethyl ester and phenylethyl alcohol

ArticleYear
Caffeic acid phenethyl ester inhibits alpha-melanocyte stimulating hormone-induced melanin synthesis through suppressing transactivation activity of microphthalmia-associated transcription factor.
    Journal of natural products, 2013, Aug-23, Volume: 76, Issue:8

    Topics: alpha-MSH; Animals; Blotting, Western; Caffeic Acids; Cyclic AMP Response Element-Binding Protein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Interferon Type I; Intramolecular Oxidoreductases; Levodopa; Melanins; Mice; Microphthalmia-Associated Transcription Factor; Molecular Structure; Monophenol Monooxygenase; Oxidoreductases; Phenylethyl Alcohol; Pregnancy Proteins; Transcriptional Activation

2013
Growth inhibition and modulation of antigenic phenotype in human melanoma and glioblastoma multiforme cells by caffeic acid phenethyl ester (CAPE)
    Cellular and molecular biology, 1992, Volume: 38, Issue:5

    Topics: Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Caffeic Acids; Cell Differentiation; Cell Division; Cytotoxins; Diterpenes; Glioblastoma; Humans; Melanoma; Mycophenolic Acid; Phenotype; Phenylethyl Alcohol; Terpenes; Tretinoin; Tumor Cells, Cultured

1992
Suppression of adenovirus type 5 E1A-mediated transformation and expression of the transformed phenotype by caffeic acid phenethyl ester (CAPE).
    Molecular carcinogenesis, 1991, Volume: 4, Issue:3

    Topics: Actins; Adenoviridae; Adenovirus Early Proteins; Animals; Caffeic Acids; Cell Line; Cell Line, Transformed; Cell Transformation, Viral; Cold Temperature; DNA; Fibroblasts; Gene Expression Regulation, Viral; Methyl Methanesulfonate; Mice; Mutation; Oncogene Proteins, Viral; Phenotype; Phenylethyl Alcohol; Rats; Rats, Inbred F344; RNA, Messenger; Transfection

1991
Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis.
    Experientia, 1988, Mar-15, Volume: 44, Issue:3

    Topics: Animals; Caffeic Acids; Cell Division; Cell Survival; Cells, Cultured; Cinnamates; Cytotoxins; DNA; Ethanol; In Vitro Techniques; Phenylethyl Alcohol; Propolis; Rats; Resins, Plant

1988
Hydroxylated aromatic inhibitors of HIV-1 integrase.
    Journal of medicinal chemistry, 1995, Oct-13, Volume: 38, Issue:21

    Topics: Animals; Antiviral Agents; Apoptosis; Base Sequence; Binding Sites; Caffeic Acids; Cell Line, Transformed; DNA; DNA Nucleotidyltransferases; Enzyme Inhibitors; HIV; Humans; Hydroxylation; Integrases; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Phenylethyl Alcohol; Rats; Structure-Activity Relationship; Tumor Cells, Cultured; Zinc Fingers

1995
Growth suppression and toxicity induced by caffeic acid phenethyl ester (CAPE) in type 5 adenovirus-transformed rat embryo cells correlate directly with transformation progression.
    Cancer research, 1994, Apr-01, Volume: 54, Issue:7

    Topics: Adenovirus E1A Proteins; Adenovirus E1B Proteins; Adenoviruses, Human; Animals; Caffeic Acids; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Cytotoxins; Embryo, Mammalian; Gene Expression; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Transcription, Genetic

1994
Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds.
    Biochemical pharmacology, 1994, Aug-03, Volume: 48, Issue:3

    Topics: Base Sequence; Caffeic Acids; Cations, Divalent; DNA; DNA Nucleotidyltransferases; Dose-Response Relationship, Drug; Flavonoids; HIV-1; Integrases; Kinetics; Molecular Sequence Data; Oligonucleotides; Phenylethyl Alcohol; Structure-Activity Relationship

1994
[Lipophilic derivatives of caffeic acid as lipoxygenase inhibitors with antioxidant properties].
    Bioorganicheskaia khimiia, 1995, Volume: 21, Issue:2

    Topics: Antioxidants; Caffeic Acids; Cell-Free System; Glycine max; Hordeum; Humans; Lipids; Lipoxygenase Inhibitors; Phenylethyl Alcohol; Reactive Oxygen Species; Urea

1995
Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells.
    Cancer research, 1995, Aug-15, Volume: 55, Issue:16

    Topics: Acetylcysteine; Animals; Apoptosis; Caffeic Acids; Catalase; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA Damage; Glutathione; Hydrogen Peroxide; Oxidation-Reduction; Phenylethyl Alcohol; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344

1995
Inhibition of tumor promoter-mediated processes in mouse skin and bovine lens by caffeic acid phenethyl ester.
    Cancer research, 1993, Mar-15, Volume: 53, Issue:6

    Topics: Animals; Caffeic Acids; Cattle; Cytotoxins; DNA; Edema; Female; Humans; Hydrogen Peroxide; In Vitro Techniques; Lens, Crystalline; Mice; Neutrophils; Ornithine Decarboxylase; Phenylethyl Alcohol; Skin; Tetradecanoylphorbol Acetate

1993
Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties.
    FEBS letters, 1993, Aug-23, Volume: 329, Issue:1-2

    Topics: Antioxidants; Caffeic Acids; Hordeum; Humans; Kinetics; Linoleic Acid; Linoleic Acids; Lipoxygenase Inhibitors; Luminescent Measurements; Neutrophils; Oxidation-Reduction; Phenylethyl Alcohol; Reactive Oxygen Species; Xanthine; Xanthine Oxidase; Xanthines

1993
Inhibition of oxidative stress in HeLa cells by chemopreventive agents.
    Cancer research, 1993, Oct-01, Volume: 53, Issue:19

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Anticarcinogenic Agents; Antineoplastic Agents; Caffeic Acids; Catechin; Deoxyguanosine; Diterpenes; DNA, Neoplasm; HeLa Cells; Humans; Hydrogen Peroxide; Hydrolyzable Tannins; Oxidation-Reduction; Phenylethyl Alcohol; Tamoxifen; Tannins; Tetradecanoylphorbol Acetate; Thymidine

1993
Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells.
    Carcinogenesis, 1996, Volume: 17, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Caffeic Acids; Carcinogens; DNA; DNA Damage; Female; HeLa Cells; Humans; Mice; Oxidative Stress; Papilloma; Phenylethyl Alcohol; Protein Biosynthesis; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate

1996
Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Aug-20, Volume: 93, Issue:17

    Topics: Base Sequence; Caffeic Acids; Cell Line; Ceramides; DNA-Binding Proteins; Histiocytes; Humans; I-kappa B Proteins; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Phenylethyl Alcohol; Phosphorylation; Protein Binding; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1996
Caffeic acid phenethyl ester inhibits proliferation of human keratinocytes and interferes with the EGF regulation of ornithine decarboxylase.
    Oncology research, 1995, Volume: 7, Issue:9

    Topics: Binding Sites; Blotting, Northern; Blotting, Western; Caffeic Acids; Cell Division; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Humans; Keratinocytes; Male; Ornithine Decarboxylase; Phenylethyl Alcohol; Protein Kinase C; Signal Transduction; Time Factors

1995
Inhibition of ICE-family cysteine proteases rescues murine lymphocytes from lipoxygenase inhibitor-induced apoptosis.
    FEBS letters, 1996, Nov-04, Volume: 396, Issue:2-3

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caffeic Acids; Caspase 1; Cell Division; Cells, Cultured; Concanavalin A; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Lipoxygenase Inhibitors; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Phenylethyl Alcohol; Propolis; Quercetin; T-Lymphocytes; Urea

1996
Inhibitory effect of caffeic acid phenethyl ester on human leukemia HL-60 cells.
    Cancer letters, 1996, Nov-29, Volume: 108, Issue:2

    Topics: Anticarcinogenic Agents; Caffeic Acids; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Phenylethyl Alcohol

1996
Caffeic acid phenethyl ester stimulates human antioxidant response element-mediated expression of the NAD(P)H:quinone oxidoreductase (NQO1) gene.
    Cancer research, 1997, Feb-01, Volume: 57, Issue:3

    Topics: Antioxidants; Caffeic Acids; DNA; Humans; Phenylethyl Alcohol; Quinone Reductases; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

1997
The effect of propolis and its components on eicosanoid production during the inflammatory response.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 55, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Caffeic Acids; Cyclooxygenase Inhibitors; Diet; Eicosanoids; Flavanones; Flavonoids; Indomethacin; Inflammation; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Male; Masoprocol; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phenylethyl Alcohol; Propolis; Quercetin; Urea; Zymosan

1996
HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching.
    Journal of medicinal chemistry, 1997, Mar-14, Volume: 40, Issue:6

    Topics: Caffeic Acids; Chromones; Databases, Factual; Drug Design; Electrophoresis, Polyacrylamide Gel; Flavones; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Molecular Conformation; Molecular Structure; Oligodeoxyribonucleotides; Phenylethyl Alcohol

1997
Arylamide inhibitors of HIV-1 integrase.
    Journal of medicinal chemistry, 1997, Apr-11, Volume: 40, Issue:8

    Topics: Caffeic Acids; Chromatography, High Pressure Liquid; Curcumin; Cytotoxins; Dose-Response Relationship, Drug; Enzyme Inhibitors; HIV Integrase; HIV Integrase Inhibitors; NF-kappa B; Phenylethyl Alcohol; Quinones; Structure-Activity Relationship

1997
Ultraviolet B suppresses vitamin D receptor gene expression in keratinocytes.
    Biochemical and biophysical research communications, 1998, May-08, Volume: 246, Issue:1

    Topics: Caffeic Acids; Cells, Cultured; Cholecalciferol; Dose-Response Relationship, Radiation; Down-Regulation; Feedback; Gene Expression Regulation; Genes, myc; Humans; Keratinocytes; Phenylethyl Alcohol; Receptors, Calcitriol; RNA, Messenger; Signal Transduction; Sodium Salicylate; Tosylphenylalanyl Chloromethyl Ketone; Ultraviolet Rays

1998
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.
    Cancer research, 1999, May-15, Volume: 59, Issue:10

    Topics: Air; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arachidonic Acids; Caffeic Acids; Calcimycin; Carcinoma, Squamous Cell; Carrageenan; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Genetic Vectors; Humans; Indomethacin; Inflammation; Ionophores; Isoenzymes; Male; Membrane Lipids; Membrane Proteins; Mouth Mucosa; Nucleopolyhedroviruses; Phenylethyl Alcohol; Phospholipids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1999
Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats.
    Journal of pediatric surgery, 1999, Volume: 34, Issue:10

    Topics: Animals; Caffeic Acids; Cytotoxins; Evaluation Studies as Topic; Female; Intestinal Mucosa; Intestines; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury

1999
Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex.
    Oncogene, 1999, Oct-28, Volume: 18, Issue:44

    Topics: Antineoplastic Agents; Caffeic Acids; Colonic Neoplasms; Curcumin; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; I-kappa B Kinase; I-kappa B Proteins; Isoenzymes; Membrane Proteins; NF-kappa B; NF-kappaB-Inducing Kinase; Phenylethyl Alcohol; Polyenes; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1999
The effects of caffeic acid phenethyl ester (CAPE) on spinal cord ischemia/reperfusion injury in rabbits.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1999, Volume: 16, Issue:4

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Malondialdehyde; Methylprednisolone; Movement; Neuroprotective Agents; NF-kappa B; Phenylethyl Alcohol; Rabbits; Reperfusion Injury; Spinal Cord; Spinal Cord Ischemia; Superoxide Dismutase

1999
Effect of quercetin, caffeic acid and caffeic acid phenylethyl ester, solubilized in non-ionic surfactants, on histamine release in vivo and in vitro.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:1

    Topics: Animals; Antioxidants; Caffeic Acids; Cytotoxins; Histamine; Histamine Release; In Vitro Techniques; Mast Cells; Phenylethyl Alcohol; Quercetin; Rats; Rats, Wistar; Surface-Active Agents

2000
Caffeic acid phenethyl ester induces leukocyte apoptosis, modulates nuclear factor-kappa B and suppresses acute inflammation.
    Neuroimmunomodulation, 2000, Volume: 7, Issue:2

    Topics: Acute Disease; Animals; Apoptosis; Caffeic Acids; Carrageenan; Cell Survival; Dexamethasone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Humans; I-kappa B Proteins; Inflammation; Lethal Dose 50; Leukocyte Count; Leukocytes; Monocytes; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Transcription Factor RelA; Tumor Cells, Cultured

2000
Colon cancer chemopreventive drugs modulate integrin-mediated signaling pathways.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3

    Topics: Actins; Antineoplastic Agents; Caffeic Acids; Cell Movement; Colonic Neoplasms; Crk-Associated Substrate Protein; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrins; Phenylethyl Alcohol; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Signal Transduction; Sulindac; Tumor Cells, Cultured

2000
Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells.
    Cancer letters, 2000, May-29, Volume: 153, Issue:1-2

    Topics: Antineoplastic Agents; Caffeic Acids; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mouth Neoplasms; Phenylethyl Alcohol; Tumor Cells, Cultured

2000
Restoration of gap junctional intercellular communication by caffeic acid phenethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line.
    Cancer letters, 2000, Aug-31, Volume: 157, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Caffeic Acids; Cell Adhesion; Cell Communication; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Connexin 43; Epithelial Cells; Gap Junctions; Gene Expression; Genes, ras; Liver; Oncogene Protein p21(ras); Phenylethyl Alcohol; Phosphorylation; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction

2000
Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-kappaB.
    Circulation, 2000, Oct-17, Volume: 102, Issue:16

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Arteries; Caffeic Acids; Cell Survival; Cells, Cultured; Coronary Vessels; DNA-Binding Proteins; Endothelium, Vascular; Humans; I-kappa B Proteins; L-Lactate Dehydrogenase; Lipoproteins, LDL; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Up-Regulation; Vitamin E

2000
Caffeic acid phenethyl ester (CAPE): synthesis and X-ray crystallographic analysis.
    Chemical & pharmaceutical bulletin, 2001, Volume: 49, Issue:2

    Topics: Caffeic Acids; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Molecular Structure; Phenylethyl Alcohol; Spectrophotometry, Infrared

2001
Testicular nitric oxide levels after unilateral testicular torsion/detorsion in rats pretreated with caffeic acid phenethyl ester.
    Urological research, 2000, Volume: 28, Issue:6

    Topics: Animals; Caffeic Acids; Male; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Inbred Strains; Reperfusion Injury; Spermatic Cord Torsion; Testis

2000
The antioxidant caffeic acid phenethyl ester induces apoptosis associated with selective scavenging of hydrogen peroxide in human leukemic HL-60 cells.
    Anti-cancer drugs, 2001, Volume: 12, Issue:2

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Caffeic Acids; Catalase; Cell Cycle; Cytotoxins; DNA Damage; DNA, Neoplasm; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Oxidation-Reduction; Phenylethyl Alcohol; Reactive Oxygen Species; Superoxides

2001
Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester.
    Molecular carcinogenesis, 2001, Volume: 31, Issue:2

    Topics: Animals; Apoptosis; Blotting, Western; Boron Compounds; Caffeic Acids; Carcinogens; Caspase 3; Caspases; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Methacrylates; Methylmethacrylates; Mice; Phenylethyl Alcohol; Phosphorylation; Precipitin Tests; Serine; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53

2001
The effect of caffeic acid phenethyl ester on ischemia-reperfusion injury in comparison with alpha-tocopherol in rat kidneys.
    Urological research, 2001, Volume: 29, Issue:3

    Topics: alpha-Tocopherol; Animals; Antioxidants; Caffeic Acids; Female; Kidney; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Xanthine Oxidase

2001
Effects of caffeic acid phenethyl ester and epidermal growth factor on the development of caustic esophageal stricture in rats.
    Journal of pediatric surgery, 2001, Volume: 36, Issue:10

    Topics: Animals; Burns, Chemical; Caffeic Acids; Epidermal Growth Factor; Esophageal Stenosis; NF-kappa B; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Wound Healing

2001
Acute regulation of glucose transport in a human megakaryocytic cell line: difference between growth factors and H(2)O(2).
    Free radical biology & medicine, 2001, Oct-01, Volume: 31, Issue:7

    Topics: Caffeic Acids; Catalase; Deoxyglucose; Enzyme Inhibitors; Genistein; Glucose; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Hydrogen Peroxide; Interleukin-3; Kinetics; Leukemia, Megakaryoblastic, Acute; Phenylethyl Alcohol; Protein-Tyrosine Kinases; Stem Cell Factor; Thrombopoietin; Tumor Cells, Cultured

2001
Effect of propolis extract on malignant cell transformation by moloney murine sarcoma virus.
    Archives of virology, 2001, Volume: 146, Issue:8

    Topics: 3T3 Cells; Animals; Caffeic Acids; Cell Transformation, Neoplastic; Cell Transformation, Viral; Mice; Moloney murine sarcoma virus; Phenylethyl Alcohol; Propolis

2001
Effect of caffeic acid phenethyl ester, an antioxidant from propolis, on inducing apoptosis in human leukemic HL-60 cells.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:11

    Topics: Antioxidants; Apoptosis; Caffeic Acids; Cell Division; Flow Cytometry; HL-60 Cells; Humans; Phenylethyl Alcohol; Propolis

2001
Caffeic acid phenethyl ester, an inhibitor of nuclear factor-kappaB, attenuates bacterial peptidoglycan polysaccharide-induced colitis in rats.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3

    Topics: Animals; Apoptosis; Arthritis; Caffeic Acids; Cells, Cultured; Colitis; Colon; Cytokines; Disease Models, Animal; Female; Humans; NF-kappa B; Peptidoglycan; Phenylethyl Alcohol; Rats; Rats, Inbred Lew

2001
Caffeic acid phenethyl ester inhibits nitric oxide synthase gene expression and enzyme activity.
    Cancer letters, 2002, Jan-10, Volume: 175, Issue:1

    Topics: Animals; Caffeic Acids; Cell Line; Cytotoxins; DNA Primers; Gene Expression Regulation; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophages; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic

2002
Caffeic acid phenethyl ester changes the indices of oxidative stress in serum of rats with renal ischaemia-reperfusion injury.
    Cell biochemistry and function, 2001, Volume: 19, Issue:4

    Topics: Adenosine Deaminase; alpha-Tocopherol; Animals; Antioxidants; Caffeic Acids; Female; Kidney; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rats; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase

2001
Effect of caffeic acid phenethyl ester on corneal neovascularization in rats.
    Current eye research, 2001, Volume: 23, Issue:4

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caffeic Acids; Cornea; Corneal Neovascularization; Dexamethasone; Glucocorticoids; Indomethacin; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2001
Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers.
    Molecular pharmacology, 2002, Volume: 61, Issue:3

    Topics: Acetylcysteine; Animals; Astrocytes; Caffeic Acids; Cell Survival; Cells, Cultured; Curcumin; Drug Interactions; Enzyme Activation; Enzyme Induction; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Phenylethyl Alcohol; Rats; Up-Regulation

2002
Nuclear factor-kappa B-independent regulation of lipopolysaccharide-mediated interleukin-6 biosynthesis.
    Biochemical and biophysical research communications, 2002, Mar-08, Volume: 291, Issue:4

    Topics: Animals; Caffeic Acids; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Interleukin-6; Leupeptins; Lipopolysaccharides; Multienzyme Complexes; NF-kappa B; Peptides; Phenylethyl Alcohol; Proteasome Endopeptidase Complex; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Sulfasalazine

2002
Beneficial effects of caffeic acid phenethyl ester in a rat model of vascular injury.
    British journal of pharmacology, 2002, Volume: 136, Issue:3

    Topics: Actins; Angioplasty, Balloon, Coronary; Animals; Caffeic Acids; Carotid Artery Injuries; Cyclooxygenase 2; Depression, Chemical; Electrophoretic Mobility Shift Assay; Isoenzymes; Macrophages; Male; NF-kappa B; Phenylethyl Alcohol; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tunica Intima

2002
Constituents of Chinese propolis and their antiproliferative activities.
    Journal of natural products, 2002, Volume: 65, Issue:5

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Caffeic Acids; China; Chromatography, Thin Layer; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Free Radical Scavengers; Mice; Molecular Structure; Phenylethyl Alcohol; Picrates; Propolis; Spectrophotometry, Infrared; Tumor Cells, Cultured

2002
Selective antiproliferative activity of caffeic acid phenethyl ester analogues on highly liver-metastatic murine colon 26-L5 carcinoma cell line.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:10

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Division; Colonic Neoplasms; DNA Fragmentation; Drug Screening Assays, Antitumor; Hepatocytes; Humans; Liver Neoplasms; Mice; Phenylethyl Alcohol; Structure-Activity Relationship; Tumor Cells, Cultured

2002
Use of caffeic acid phenethyl ester to prevent sodium-selenite-induced cataract in rat eyes.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:8

    Topics: Animals; Antioxidants; Caffeic Acids; Cataract; Glutathione; Lens, Crystalline; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Inbred Strains; Sodium Selenite

2002
Regulation of Fas (CD95)-induced apoptosis by nuclear factor-kappaB and tumor necrosis factor-alpha in macrophages.
    American journal of physiology. Cell physiology, 2002, Volume: 283, Issue:3

    Topics: Animals; Antibodies; Apoptosis; Caffeic Acids; Cell Line; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Fas Ligand Protein; fas Receptor; Flow Cytometry; Genes, Reporter; Macrophages; Membrane Glycoproteins; Mice; NF-kappa B; Phenylethyl Alcohol; Promoter Regions, Genetic; Recombinant Fusion Proteins; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha

2002
Inhibition of angiogenesis by propolis.
    Archives of pharmacal research, 2002, Volume: 25, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Caffeic Acids; Cattle; Cell Division; Chick Embryo; Chorion; Endothelium, Vascular; Ethanol; Keratolytic Agents; Membranes; Phenylethyl Alcohol; Propolis; Pulmonary Artery; Solvents; Tetrazolium Salts; Thiazoles; Tretinoin

2002
The protective role of caffeic acid phenethyl ester (CAPE) on testicular tissue after testicular torsion and detorsion.
    World journal of urology, 2002, Volume: 20, Issue:4

    Topics: Animals; Caffeic Acids; Catalase; Disease Models, Animal; Glutathione Peroxidase; Male; Peroxidase; Phenylethyl Alcohol; Protective Agents; Rats; Reperfusion Injury; Spermatic Cord Torsion; Superoxide Dismutase; Testis; Thiobarbituric Acid Reactive Substances

2002
The inhibitory effect of propolis and caffeic acid phenethyl ester on cyclooxygenase activity in J774 macrophages.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2002, Volume: 9, Issue:6

    Topics: Animals; Caffeic Acids; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Flavonoids; Isoenzymes; Macrophages; Phenylethyl Alcohol; Propolis; Prostaglandin-Endoperoxide Synthases

2002
Effect of caffeic acid phenethyl ester on cartilage in experimental osteoarthritis.
    Rheumatology international, 2002, Volume: 22, Issue:6

    Topics: Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Caffeic Acids; Cartilage, Articular; Disease Models, Animal; Disease Progression; Extracellular Matrix; Hindlimb; Injections, Intra-Articular; NF-kappa B; Osteoarthritis, Knee; Phenylethyl Alcohol; Proteoglycans; Rabbits

2002
Antioxidant activity of propolis: role of caffeic acid phenethyl ester and galangin.
    Fitoterapia, 2002, Volume: 73 Suppl 1

    Topics: Antioxidants; Biphenyl Compounds; Caffeic Acids; Dose-Response Relationship, Drug; Flavonoids; Free Radical Scavengers; Humans; Lipid Peroxidation; Phenylethyl Alcohol; Phytotherapy; Picrates; Plant Extracts; Propolis; Xanthine Oxidase

2002
The role of the phenethyl ester of caffeic acid (CAPE) in the inhibition of rat lung cyclooxygenase activity by propolis.
    Fitoterapia, 2002, Volume: 73 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Flavonoids; Inhibitory Concentration 50; Lipopolysaccharides; Lung; Male; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Propolis; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar

2002
Effect of a propolis extract and caffeic acid phenethyl ester on formation of aberrant crypt foci and tumors in the rat colon.
    Fitoterapia, 2002, Volume: 73 Suppl 1

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Caffeic Acids; Colon; Colonic Neoplasms; Male; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Propolis; Random Allocation; Rats; Rats, Wistar

2002
In vitro permeation through porcine buccal mucosa of caffeic acid phenetyl ester (CAPE) from a topical mucoadhesive gel containing propolis.
    Fitoterapia, 2002, Volume: 73 Suppl 1

    Topics: Adhesiveness; Administration, Topical; Animals; Anti-Inflammatory Agents; Caffeic Acids; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Gels; Humans; Male; Mouth Mucosa; Permeability; Phenylethyl Alcohol; Phytotherapy; Propolis; Stomatitis; Swine; Time Factors

2002
Phytochemical compounds involved in the anti-inflammatory effect of propolis extract.
    Fitoterapia, 2002, Volume: 73 Suppl 1

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis; Caffeic Acids; Carrageenan; Cell Division; Chronic Disease; Edema; Flavonoids; Male; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Pleurisy; Propolis; Rats; Rats, Inbred Lew; Rats, Wistar; T-Lymphocytes; Time Factors

2002
NF-kappaB activation is essential for angiotensin II-dependent proliferation and migration of vascular smooth muscle cells.
    Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:12

    Topics: Angioplasty, Balloon, Coronary; Angiotensin II; Animals; Anti-Infective Agents; Caffeic Acids; Cell Division; Cell Movement; Heart; Muscle, Smooth, Vascular; NF-kappa B; Nitriles; Organ Culture Techniques; Phenylethyl Alcohol; Phosphorylation; Receptors, Angiotensin; Sulfones; Sus scrofa

2002
Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element.
    The Biochemical journal, 2003, May-01, Volume: 371, Issue:Pt 3

    Topics: Animals; Antioxidants; Blotting, Western; Caffeic Acids; Carrier Proteins; Curcumin; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); LLC-PK1 Cells; NF-E2-Related Factor 2; Phenylethyl Alcohol; Promoter Regions, Genetic; Trans-Activators

2003
Caffeic acid phenethyl ester (CAPE) analogues: potent nitric oxide inhibitors from the Netherlands propolis.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:4

    Topics: Animals; Caffeic Acids; Cell Line; Macrophages; Mice; Netherlands; Nitric Oxide; Phenylethyl Alcohol; Propolis

2003
Chlamydophila pneumoniae induces ICAM-1 expression in human aortic endothelial cells via protein kinase C-dependent activation of nuclear factor-kappaB.
    Circulation research, 2003, May-30, Volume: 92, Issue:10

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aorta; Caffeic Acids; Cell Membrane; Cells, Cultured; Chlamydophila Infections; Chlamydophila pneumoniae; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Humans; Immunoblotting; Intercellular Adhesion Molecule-1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Phenylethyl Alcohol; Protein Kinase C; RNA, Messenger; Signal Transduction; Sulfones; Up-Regulation

2003
Vascular effects of caffeic acid phenethyl ester (CAPE) on isolated rat thoracic aorta.
    Life sciences, 2003, May-23, Volume: 73, Issue:1

    Topics: Animals; Aorta, Thoracic; Caffeic Acids; Calcium; Cytosol; Enzyme Inhibitors; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Phenylethyl Alcohol; Potassium Chloride; Rats; Rats, Wistar; Vasoconstrictor Agents

2003
Inhibitory effects of caffeic acid phenethyl ester analogues on experimental lung metastasis of murine colon 26-L5 carcinoma cells.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Caffeic Acids; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Phenylethyl Alcohol; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2003
Effect of caffeic acid phenethyl ester on proliferation and apoptosis of hepatic stellate cells in vitro.
    World journal of gastroenterology, 2003, Volume: 9, Issue:6

    Topics: Animals; Apoptosis; Caffeic Acids; Cell Division; Cells, Cultured; Liver; Male; Phenylethyl Alcohol; Rats; Rats, Wistar

2003
Effect of propolis on human cartilage and chondrocytes.
    Life sciences, 2003, Jul-11, Volume: 73, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Cartilage; Cartilage, Articular; Cell Separation; Cells, Cultured; Chondrocytes; Glycosaminoglycans; Humans; Indomethacin; Nitric Oxide; Nitrites; Organ Culture Techniques; Phenylethyl Alcohol; Propolis

2003
Caffeic acid phenethyl ester (CAPE) prevents inflammatory stress in organotypic hippocampal slice cultures.
    Brain research. Molecular brain research, 2003, Jul-23, Volume: 115, Issue:2

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Caenorhabditis elegans Proteins; Caffeic Acids; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Hippocampus; Immunohistochemistry; Inflammation; Interferon-gamma; Lipopolysaccharides; NF-kappa B; Nitrites; Organ Culture Techniques; Phenylethyl Alcohol; Rats; Rats, Wistar; Stress, Physiological; Tumor Necrosis Factor-alpha

2003
The effects of caffeic acid phenethyl ester on tissue damage in lung after hindlimb ischemia-reperfusion.
    Pharmacological research, 2003, Volume: 48, Issue:4

    Topics: Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Caffeic Acids; Capillary Permeability; Hindlimb; Injections, Intraperitoneal; Lung; Male; Malondialdehyde; Neutrophil Infiltration; Peroxidase; Phenylethyl Alcohol; Proteins; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Sodium-Potassium-Exchanging ATPase; Time Factors; Tourniquets; Turkey

2003
Effects of caffeic acid phenethyl ester and alpha-tocopherol on reperfusion injury in rat brain.
    Cell biochemistry and function, 2003, Volume: 21, Issue:3

    Topics: Adenosine Deaminase; alpha-Tocopherol; Animals; Brain; Brain Chemistry; Caffeic Acids; Catalase; Data Interpretation, Statistical; Glutathione Peroxidase; Heart; Male; Malondialdehyde; Myocardium; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Statistics, Nonparametric; Superoxide Dismutase; Xanthine Oxidase

2003
Regulation of microglial inflammatory response by histone deacetylase inhibitors.
    Journal of neurochemistry, 2003, Volume: 87, Issue:2

    Topics: Animals; Caffeic Acids; Cells, Cultured; Coculture Techniques; DNA; Drug Synergism; Enzyme Inhibitors; Hippocampus; Histone Deacetylase Inhibitors; Inflammation; Interleukin-6; Lipopolysaccharides; Mice; Microglia; Neurons; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Rats; Rats, Wistar; RNA, Messenger; Sesquiterpenes; Sesquiterpenes, Guaiane

2003
Caffeic acid phenethyl ester blocks apoptosis induced by low potassium in cerebellar granule cells.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2003, Volume: 21, Issue:7

    Topics: Animals; Animals, Newborn; Apoptosis; Caffeic Acids; Caspase 3; Caspase 9; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Cerebellum; Culture Media; Neurons; NF-kappa B; Phenylethyl Alcohol; Potassium; Rats; Rats, Wistar; Reactive Oxygen Species

2003
Caffeic acid phenethyl ester inhibits T-cell activation by targeting both nuclear factor of activated T-cells and NF-kappaB transcription factors.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:3

    Topics: Caffeic Acids; Cell Cycle; Cell Division; DNA-Binding Proteins; Humans; Interleukin-2; Jurkat Cells; Lymphocyte Activation; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Phenylethyl Alcohol; Phosphorylation; Promoter Regions, Genetic; T-Lymphocytes; Transcription Factors; Transcriptional Activation

2004
Caffeic acid phenethyl ester induces apoptosis by inhibition of NFkappaB and activation of Fas in human breast cancer MCF-7 cells.
    The Journal of biological chemistry, 2004, Feb-13, Volume: 279, Issue:7

    Topics: Adenoviridae; Apoptosis; Arabidopsis Proteins; bcl-2-Associated X Protein; Caffeic Acids; Caspase 8; Caspase 9; Caspases; Cell Line, Tumor; Cell Nucleus; Cross-Linking Reagents; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; fas Receptor; Fatty Acid Desaturases; Genes, Dominant; Genes, Reporter; Genetic Vectors; Humans; I-kappa B Proteins; Immunoblotting; K562 Cells; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Signal Transduction; Time Factors; Transfection; Tumor Suppressor Protein p53

2004
Involvement of tumor suppressor protein p53 and p38 MAPK in caffeic acid phenethyl ester-induced apoptosis of C6 glioma cells.
    Biochemical pharmacology, 2003, Dec-15, Volume: 66, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caffeic Acids; Caspase 3; Caspases; Cytochromes c; Glioma; Imidazoles; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Phosphorylation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Serine; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2003
Propolin C from propolis induces apoptosis through activating caspases, Bid and cytochrome c release in human melanoma cells.
    Biochemical pharmacology, 2004, Jan-01, Volume: 67, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Caffeic Acids; Carrier Proteins; Caspases; Cell Cycle; Cell Division; Cell Survival; Cytochromes c; DNA Fragmentation; Enzyme Activation; Flavonoids; Free Radicals; Humans; Melanoma; Mitochondria; Phenylethyl Alcohol; Propolis; Xanthine Oxidase

2004
Role of curcumin and the inhibition of NF-kappaB in the onset of chemotherapy-induced mucosal barrier injury.
    Leukemia, 2004, Volume: 18, Issue:2

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line; Curcumin; Cytarabine; Drug Interactions; Female; Intestinal Mucosa; Methotrexate; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Inbred Strains

2004
Protective role of alpha-tocopherol and caffeic acid phenethyl ester on ischemia-reperfusion injury via nitric oxide and myeloperoxidase in rat kidneys.
    Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 339, Issue:1-2

    Topics: alpha-Tocopherol; Animals; Antioxidants; Caffeic Acids; Catalase; Kidney; Nitric Oxide; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase

2004
Inhibitory effect of caffeic acid phenethyl ester on bleomycine-induced lung fibrosis in rats.
    Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 339, Issue:1-2

    Topics: Animals; Antioxidants; Bleomycin; Caffeic Acids; Catalase; Hydroxyproline; Lung; Male; Malondialdehyde; Molecular Structure; Nitric Oxide; Organ Size; Peroxidase; Phenylethyl Alcohol; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vitamin E

2004
Inhibitory effect of caffeic acid phenethyl ester on angiogenesis, tumor invasion, and metastasis.
    Journal of agricultural and food chemistry, 2003, Dec-31, Volume: 51, Issue:27

    Topics: Adenocarcinoma; Animals; Caffeic Acids; Cell Division; Cell Survival; Colonic Neoplasms; Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Phenylethyl Alcohol; Umbilical Veins; Vascular Endothelial Growth Factor A

2003
Sulindac sulfide and caffeic acid phenethyl ester suppress the motility of lung adenocarcinoma cells promoted by transforming growth factor-beta through Akt inhibition.
    Journal of cancer research and clinical oncology, 2004, Volume: 130, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Caffeic Acids; Catechin; Cell Movement; Curcumin; Humans; Lung Neoplasms; Neovascularization, Pathologic; NF-kappa B; Phenylethyl Alcohol; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sulindac; Transforming Growth Factor beta; Tumor Cells, Cultured

2004
Chemoprotective effect of caffeic acid phenethyl ester on promotion in a medium-term rat hepatocarcinogenesis assay.
    International journal of cancer, 2004, Feb-10, Volume: 108, Issue:4

    Topics: Animals; Blotting, Western; Caffeic Acids; Carcinoma, Hepatocellular; Cell Nucleus; Disease Models, Animal; Disease Progression; gamma-Glutamyltransferase; Gene Expression Regulation; Glutathione S-Transferase pi; Glutathione Transferase; Humans; I-kappa B Proteins; Isoenzymes; Liver Neoplasms, Experimental; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Precancerous Conditions; Protein Transport; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2004
Interleukin-1beta induces macrophage inflammatory protein-1beta expression in human hepatocytes.
    Cellular immunology, 2003, Volume: 226, Issue:1

    Topics: Caffeic Acids; Cell Line, Tumor; Chemokine CCL4; Gene Expression Regulation; Hepatocytes; Humans; Interleukin-1; Macrophage Inflammatory Proteins; Macrophages; NF-kappa B; Phenylethyl Alcohol; Promoter Regions, Genetic; Receptors, CCR5

2003
Acute induction of inflammatory cytokine expression after gamma-irradiation in the rat: effect of an NF-kappaB inhibitor.
    International journal of radiation oncology, biology, physics, 2004, Feb-01, Volume: 58, Issue:2

    Topics: Animals; Caffeic Acids; Enteritis; Gamma Rays; Ileum; Interleukin-1; Interleukin-10; Interleukin-6; Interleukin-8; Interleukins; Male; Muscle, Smooth; NF-kappa B; Phenylethyl Alcohol; Radiation Injuries; Rats; Rats, Wistar; Receptors, Interleukin-6; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Time Factors; Transcription Factors; Tumor Necrosis Factor-alpha; Whole-Body Irradiation

2004
The effect of CAPE on lipid peroxidation and nitric oxide levels in the plasma of rats following thermal injury.
    Burns : journal of the International Society for Burn Injuries, 2004, Volume: 30, Issue:2

    Topics: Animals; Antioxidants; Burns; Caffeic Acids; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Xanthine Oxidase

2004
Native LDL induces interleukin-8 expression via H2O2, p38 Kinase, and activator protein-1 in human aortic smooth muscle cells.
    Cardiovascular research, 2004, Apr-01, Volume: 62, Issue:1

    Topics: Aorta; Caffeic Acids; Cells, Cultured; Coronary Vessels; Dactinomycin; Dose-Response Relationship, Drug; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Interleukin-8; Lipoproteins, LDL; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Pyridines; Sesquiterpenes; Time Factors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2004
Immunomodulatory effect of caffeic acid phenethyl ester in Balb/c mice.
    International immunopharmacology, 2004, Volume: 4, Issue:3

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Body Weight; Caffeic Acids; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Female; Flow Cytometry; Immunoglobulin M; Immunophenotyping; Mice; Mice, Inbred BALB C; Mitogens; Organ Size; Phenylethyl Alcohol; Spleen; Thymus Gland

2004
Stimulatory actions of caffeic acid phenethyl ester, a known inhibitor of NF-kappaB activation, on Ca2+-activated K+ current in pituitary GH3 cells.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Amidines; Animals; Caffeic Acids; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Electric Conductivity; Ion Channel Gating; Masoprocol; Membrane Potentials; NF-kappa B; Patch-Clamp Techniques; Phenylethyl Alcohol; Pituitary Gland; Potassium Channels, Calcium-Activated; Rats; Riluzole; tert-Butylhydroperoxide

2004
Stage-dependent modulation of limb regeneration by caffeic acid phenethyl ester (CAPE)--immunocytochemical evidence of a CAPE-evoked delay in mesenchyme formation and limb regeneration.
    Journal of experimental zoology. Part A, Comparative experimental biology, 2004, May-01, Volume: 301, Issue:5

    Topics: Analysis of Variance; Animals; Autoradiography; Caffeic Acids; Extremities; Immunoenzyme Techniques; Immunohistochemistry; Keratinocytes; Mesoderm; Phenylethyl Alcohol; Regeneration; Salamandridae; Thymidine; Tritium; Vimentin; Wound Healing

2004
Use of caffeic acid phenethyl ester and cortisone may prevent proliferative vitreoretinopathy.
    Mediators of inflammation, 2004, Volume: 13, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cortisone; Female; Glutathione; Male; Nitrites; Phenylethyl Alcohol; Rabbits; Retina; Vitreoretinopathy, Proliferative; Vitreous Body

2004
Protective effects of caffeic acid phenethyl ester against experimental allergic encephalomyelitis-induced oxidative stress in rats.
    Free radical biology & medicine, 2004, Aug-01, Volume: 37, Issue:3

    Topics: Animals; Biomarkers; Brain; Caffeic Acids; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Spinal Cord

2004
Caffeic acid phenethyl ester-induced PC-3 cell apoptosis is caspase-dependent and mediated through the loss of inhibitors of apoptosis proteins.
    BJU international, 2004, Volume: 94, Issue:3

    Topics: Apoptosis; Blotting, Western; Caffeic Acids; Caspase Inhibitors; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Male; NF-kappa B; Paclitaxel; Phenylethyl Alcohol; Prostatic Neoplasms; Tumor Necrosis Factor-alpha

2004
Reduction of ischemia--reperfusion induced myocardial infarct size in rats by caffeic acid phenethyl ester (CAPE).
    Clinical biochemistry, 2004, Volume: 37, Issue:8

    Topics: Animals; Antioxidants; Caffeic Acids; Free Radicals; Lipoxygenase; Male; Myocardial Infarction; Myocardium; Neutrophils; Oxidative Stress; Oxygen; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Xanthine Oxidase

2004
Cell killing and radiosensitization by caffeic acid phenethyl ester (CAPE) in lung cancer cells.
    Journal of radiation research, 2004, Volume: 45, Issue:2

    Topics: Adenocarcinoma; Apoptosis; Caffeic Acids; Cell Line; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Lung Neoplasms; Phenylethyl Alcohol; Radiation Tolerance; Radiation-Sensitizing Agents

2004
Caffeic acid phenethyl ester ameliorated ototoxicity induced by cisplatin in rats.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16, Issue:4

    Topics: Analysis of Variance; Animals; Caffeic Acids; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Hearing Loss, Sensorineural; Otoacoustic Emissions, Spontaneous; Phenylethyl Alcohol; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric

2004
Quantitative analysis of caffeic acid phenethyl ester in crude propolis by liquid chromatography-electrospray ionization mass spectrometry.
    Journal of separation science, 2004, Volume: 27, Issue:7-8

    Topics: Caffeic Acids; Chromatography, Liquid; Cytotoxins; Indicators and Reagents; Phenylethyl Alcohol; Propolis; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2004
Protective effects of caffeic acid phenethyl ester (CAPE) on carbon tetrachloride-induced hepatotoxicity in rats.
    Acta histochemica, 2004, Volume: 106, Issue:4

    Topics: Animals; Caffeic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytotoxins; Drug Therapy, Combination; Liver; Liver Cirrhosis; Liver Function Tests; Male; Phenylethyl Alcohol; Rats; Rats, Wistar

2004
[The nitrosative effect of peripheral ischemia-reperfusion on lung and preventive of caffeic acid phenethyl ester].
    Tuberkuloz ve toraks, 2004, Volume: 52, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Caffeic Acids; Capillary Permeability; Cytokines; Hindlimb; Lung; Male; Malondialdehyde; Neutrophil Infiltration; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Tourniquets; Tyrosine

2004
Development and validation of a liquid chromatographic-tandem mass spectrometric method for the determination of caffeic acid phenethyl ester in rat plasma and urine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Oct-15, Volume: 810, Issue:1

    Topics: Animals; Caffeic Acids; Chromatography, High Pressure Liquid; Glucuronidase; Glucuronides; Male; Phenylethyl Alcohol; Rats; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2004
Caffeic acid phenethyl ester as a protective agent against doxorubicin nephrotoxicity in rats.
    Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 348, Issue:1-2

    Topics: Animals; Antioxidants; Caffeic Acids; Doxorubicin; Drug Interactions; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Nitric Oxide; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley

2004
Co-operative functions between nuclear factors NFkappaB and CCAT/enhancer-binding protein-beta (C/EBP-beta) regulate the IL-6 promoter in autocrine human prostate cancer cells.
    The Prostate, 2004, Dec-01, Volume: 61, Issue:4

    Topics: Base Sequence; Binding Sites; Blotting, Western; Caffeic Acids; CCAAT-Enhancer-Binding Protein-beta; DNA; Gene Expression Regulation; Humans; I-kappa B Proteins; Immunohistochemistry; Interleukin-6; Male; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Promoter Regions, Genetic; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2004
Interleukin-1beta upregulates functional expression of neurokinin-1 receptor (NK-1R) via NF-kappaB in astrocytes.
    Glia, 2004, Nov-15, Volume: 48, Issue:3

    Topics: Animals; Animals, Newborn; Astrocytes; Biphenyl Compounds; Caffeic Acids; Calcium; Calcium Signaling; Cell Line, Tumor; Cells, Cultured; Central Nervous System; Cytosol; Encephalitis; Gene Expression Regulation; Humans; Interleukin-1; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Up-Regulation

2004
Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver.
    Journal of biochemical and molecular toxicology, 2004, Volume: 18, Issue:4

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2004
Caffeic acid phenethyl ester prevents neonatal hypoxic-ischaemic brain injury.
    Brain : a journal of neurology, 2004, Volume: 127, Issue:Pt 12

    Topics: Animals; Animals, Newborn; Caffeic Acids; Calcium; Caspase 3; Caspases; Cells, Cultured; Cytochromes c; Drug Evaluation, Preclinical; Enzyme Activation; Hypoxia-Ischemia, Brain; Mitochondria; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2004
Effects of caffeic acid phenethyl ester on glycerol-induced acute renal failure in rats.
    Clinical and experimental pharmacology & physiology, 2004, Volume: 31, Issue:9

    Topics: Acute Kidney Injury; Animals; Antioxidants; Caffeic Acids; Glycerol; Injections, Intramuscular; Kidney; Lipid Peroxidation; Male; Myoglobinuria; Necrosis; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar

2004
Oral flavonoid supplementation attenuates atherosclerosis development in apolipoprotein E-deficient mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aorta, Thoracic; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Caffeic Acids; Cell Adhesion Molecules; Cytokines; Depression, Chemical; Drug Evaluation, Preclinical; Extracellular Matrix Proteins; Free Radical Scavengers; Gene Expression Profiling; Gene Expression Regulation; Hyperlipoproteinemia Type II; Isoprostanes; Lipids; Male; Mice; Mice, Knockout; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Transcription Factors

2005
Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:14

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Humans; Liver Neoplasms; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Neoplasm Metastasis; NF-kappa B; Phenylethyl Alcohol; Transcription, Genetic

2004
Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Animals; Aurintricarboxylic Acid; Caffeic Acids; Cattle; Cell Survival; Chalcone; Chalcones; Curcumin; Endothelial Cells; Enzyme Activation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Mitogen-Activated Protein Kinases; Oxidative Stress; Phenylethyl Alcohol

2005
The protective effect of caffeic acid phenethyl ester on ischemia-reperfusion injury in rat ovary.
    European journal of obstetrics, gynecology, and reproductive biology, 2004, Dec-01, Volume: 117, Issue:2

    Topics: Animals; Antioxidants; Caffeic Acids; Female; Lipid Peroxidation; Models, Animal; Ovarian Diseases; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Torsion Abnormality

2004
Caffeic acid phenethyl ester improves oxidative organ damage in rat model of thermal trauma.
    Physiological research, 2004, Volume: 53, Issue:6

    Topics: Animals; Burns; Caffeic Acids; Disease Models, Animal; Injections, Intraperitoneal; Kidney Diseases; Lung Diseases; Male; Malondialdehyde; Multiple Organ Failure; Oxidoreductases; Phenylethyl Alcohol; Rats; Rats, Wistar; Treatment Outcome

2004
Protective role of caffeic acid phenethyl ester (cape) on gentamicin-induced acute renal toxicity in rats.
    Toxicology, 2005, Feb-14, Volume: 207, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Caffeic Acids; Catalase; Female; Free Radical Scavengers; Gentamicins; Glutathione; Kidney; Kidney Tubular Necrosis, Acute; Malondialdehyde; Medicine, Traditional; Nitric Oxide; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase

2005
Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart.
    Clinical biochemistry, 2005, Volume: 38, Issue:2

    Topics: Animals; Antioxidants; Caffeic Acids; Diabetes Mellitus, Experimental; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Oxidative Stress; Oxidoreductases; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2005
Inhibition of cyclooxygenase-2 expression and restoration of gap junction intercellular communication in H-ras-transformed rat liver epithelial cells by caffeic acid phenethyl ester.
    Annals of the New York Academy of Sciences, 2004, Volume: 1030

    Topics: Animals; Base Sequence; Blotting, Western; Caffeic Acids; Cell Communication; Cell Line, Transformed; Cyclooxygenase 2; DNA Primers; DNA Probes; Electrophoretic Mobility Shift Assay; Gap Junctions; Genes, ras; Liver; Phenylethyl Alcohol; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Rats

2004
Caffeic acid phenethyl ester exerts a neuroprotective effect on CNS against pentylenetetrazol-induced seizures in mice.
    Neurochemical research, 2004, Volume: 29, Issue:12

    Topics: Animals; Antioxidants; Biomarkers; Caffeic Acids; Central Nervous System; Convulsants; Female; Malondialdehyde; Mice; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Oxidants; Oxidative Stress; Pentylenetetrazole; Phenylethyl Alcohol; Reactive Oxygen Species; Seizures; Superoxide Dismutase; Xanthine Oxidase

2004
Interference of arachidonic acid and its metabolites with TNF-alpha release by ochratoxin A from rat liver.
    Toxicology, 2005, Mar-30, Volume: 208, Issue:3

    Topics: Animals; Arachidonic Acid; Aristolochic Acids; Caffeic Acids; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Liver; Male; NF-kappa B; Ochratoxins; Phenylethyl Alcohol; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha

2005
Caffeic acid phenethyl ester protects kidneys against carbon tetrachloride toxicity in rats.
    Journal of ethnopharmacology, 2005, Feb-28, Volume: 97, Issue:2

    Topics: Animals; Caffeic Acids; Carbon Tetrachloride Poisoning; Creatinine; Kidney; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Wistar; Urea

2005
Chlorogenate hydrolase-catalyzed synthesis of hydroxycinnamic acid ester derivatives by transesterification, substitution of bromine, and condensation reactions.
    Applied microbiology and biotechnology, 2005, Volume: 68, Issue:2

    Topics: Aspergillus; Bromine; Caffeic Acids; Chlorogenic Acid; Coumaric Acids; Esterification; Esters; Ethylene Dibromide; Hydrogen-Ion Concentration; Hydrolases; Phenylethyl Alcohol

2005
Protective effect of caffeic acid phenethyl ester (CAPE) on myocardial ischemia-reperfusion-induced apoptotic cell death.
    Toxicology, 2005, Apr-01, Volume: 209, Issue:1

    Topics: Animals; Apoptosis; Caffeic Acids; Cell Death; Cytoprotection; Free Radical Scavengers; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phenylethyl Alcohol; Rats; Rats, Wistar

2005
[Xanthine oxidase inhibitory activity and hypouricemia effect of propolis in rats].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:3

    Topics: Animals; Anti-Infective Agents; Brazil; Caffeic Acids; China; Coumaric Acids; Disease Models, Animal; Flavonoids; Gout; Hyperuricemia; Male; Oxonic Acid; Phenylethyl Alcohol; Phenylpropionates; Propionates; Propolis; Rats; Rats, Sprague-Dawley; Uric Acid; Xanthine Oxidase

2005
Gentamicin-induced nephrotoxicity and protective effect of caffeic acid phenethyl ester in rats.
    Fundamental & clinical pharmacology, 2005, Volume: 19, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Caffeic Acids; Female; Gentamicins; Lipid Peroxidation; Nephrosis; Phenylethyl Alcohol; Rats; Rats, Wistar

2005
Properties of BK(Ca) channels in oral keratinocytes.
    Journal of dental research, 2005, Volume: 84, Issue:5

    Topics: Apamin; Caffeic Acids; Carcinoma, Squamous Cell; Cell Line, Tumor; Cells, Cultured; Decanoic Acids; Electrochemistry; Humans; Hydroxy Acids; Indoles; Ion Transport; Keratinocytes; Mouth Mucosa; Mouth Neoplasms; NF-kappa B; Patch-Clamp Techniques; Peptides; Phenylethyl Alcohol; Potassium; Potassium Channel Blockers; Potassium Channels, Calcium-Activated

2005
A novel antioxidant agent caffeic acid phenethyl ester prevents shock wave-induced renal tubular oxidative stress.
    Urological research, 2005, Volume: 33, Issue:3

    Topics: Acetylglucosaminidase; Animals; Antioxidants; Caffeic Acids; Kidney Tubules; Lithotripsy; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rabbits

2005
Inhibitory effect of caffeic acid phenethyl ester on the growth of C6 glioma cells in vitro and in vivo.
    Cancer letters, 2006, Mar-28, Volume: 234, Issue:2

    Topics: Animals; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Glioma; Immunoblotting; Immunohistochemistry; In Vitro Techniques; Mice; Neoplasms, Experimental; Phenylethyl Alcohol; Rats; Retinoblastoma Protein

2006
Cytotoxicity of phenolic acid phenethyl esters on oral cancer cells.
    Cancer letters, 2005, Jun-01, Volume: 223, Issue:1

    Topics: Caffeic Acids; Carcinoma, Squamous Cell; Cell Line, Tumor; Humans; Hydroxybenzoates; Phenylethyl Alcohol; Structure-Activity Relationship; Tongue Neoplasms

2005
Caffeic acid phenethyl ester (CAPE) supplemented St. Thomas' hospital cardioplegic solution improves the antioxidant defense system of rat myocardium during ischemia-reperfusion injury.
    Pharmacological research, 2005, Volume: 52, Issue:3

    Topics: Animals; Antioxidants; Caffeic Acids; Cardioplegic Solutions; Catalase; Free Radical Scavengers; Heart; In Vitro Techniques; Male; Malondialdehyde; Myocardial Reperfusion Injury; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tyrosine

2005
Effects of melatonin and caffeic acid phenethyl ester on testicular injury induced by myocardial ischemia/reperfusion in rats.
    Fundamental & clinical pharmacology, 2005, Volume: 19, Issue:3

    Topics: Animals; Antioxidants; Atrophy; Blood Pressure; Caffeic Acids; Free Radicals; Male; Malondialdehyde; Melatonin; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Testicular Diseases; Testis

2005
Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway.
    Brain research, 2005, Jun-28, Volume: 1048, Issue:1-2

    Topics: Animals; Blotting, Western; Brain; Caffeic Acids; Capillary Permeability; Cattle; Cells, Cultured; Dextrans; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; NF-kappa B; Nitriles; Oncogene Proteins v-rel; Phenylethyl Alcohol; Proline; Signal Transduction; Sulfones; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha

2005
Effects of caffeic acid phenethyl ester on lipopolysaccharide-induced lung injury in rats.
    Pulmonary pharmacology & therapeutics, 2006, Volume: 19, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Lipopolysaccharides; Lung; Male; Malondialdehyde; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Respiratory Distress Syndrome; Sodium-Potassium-Exchanging ATPase

2006
The protective effect of caffeic acid phenethyl ester against cyclosporine A-induced cardiotoxicity in rats.
    Toxicology, 2005, Sep-01, Volume: 212, Issue:2-3

    Topics: Animals; Caffeic Acids; Cyclosporine; Electron Transport Complex IV; Heart Diseases; Immunosuppressive Agents; Male; Matrix Metalloproteinase 2; Myocardium; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Tissue Inhibitor of Metalloproteinase-2

2005
Neoflavonoids and related constituents from Nepalese propolis and their nitric oxide production inhibitory activity.
    Journal of natural products, 2005, Volume: 68, Issue:6

    Topics: Caffeic Acids; Flavonoids; Inhibitory Concentration 50; Lipopolysaccharides; Macrophages; Molecular Structure; Nepal; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; omega-N-Methylarginine; Phenylethyl Alcohol; Propolis

2005
The activities of liver adenosine deaminase, xanthine oxidase, catalase, superoxide dismutase enzymes and the levels of malondialdehyde and nitric oxide after cisplatin toxicity in rats: protective effect of caffeic acid phenethyl ester.
    Toxicology and industrial health, 2005, Volume: 21, Issue:3-4

    Topics: Adenosine Deaminase; Animals; Antineoplastic Agents; Caffeic Acids; Catalase; Cisplatin; Liver; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Protective Agents; Rats; Superoxide Dismutase; Xanthine Oxidase

2005
Myocardial ischemia/reperfusion-induced oxidative renal damage in rats: protection by caffeic acid phenethyl ester (CAPE).
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:1

    Topics: Animals; Caffeic Acids; Kidney Diseases; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2005
Effects of CAPE-like compounds on HIV replication in vitro and modulation of cytokines in vivo.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:2

    Topics: Animals; Anti-HIV Agents; Caffeic Acids; Cell Survival; Cytokines; Female; HIV-1; Humans; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; Molecular Structure; Phenylethyl Alcohol; Virus Replication

2005
Caffeic acid phenyl ester in propolis is a strong inhibitor of matrix metalloproteinase-9 and invasion inhibitor: isolation and identification.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 362, Issue:1-2

    Topics: Animals; Caffeic Acids; Cell Movement; Cell Survival; Cells, Cultured; Humans; Liver Neoplasms; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Molecular Structure; Neoplasm Invasiveness; Phenylethyl Alcohol; Propolis

2005
Ischemia-reperfusion leads to depletion of glutathione content and augmentation of malondialdehyde production in the rat heart from overproduction of oxidants: can caffeic acid phenethyl ester (CAPE) protect the heart?
    Molecular and cellular biochemistry, 2005, Volume: 273, Issue:1-2

    Topics: Animals; Antioxidants; Caffeic Acids; Cardiotonic Agents; Free Radicals; Glutathione; Heart; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; NF-kappa B; Oxidative Stress; Oxygen; Phenylethyl Alcohol; Rats; Rats, Wistar

2005
Oleic acid-induced lung injury in rats and effects of caffeic acid phenethyl ester.
    Experimental lung research, 2005, Volume: 31, Issue:5

    Topics: Animals; Bronchoalveolar Lavage Fluid; Caffeic Acids; Female; Lung; Lung Diseases; Malondialdehyde; Oleic Acid; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

2005
Role of nitric oxide in regulating secreted phospholipase A2 release from astrocytes.
    Neuroreport, 2005, Aug-22, Volume: 16, Issue:12

    Topics: Analysis of Variance; Animals; Astrocytes; Blotting, Western; Caffeic Acids; Cells, Cultured; Cerebral Cortex; Chelating Agents; Drug Interactions; Edetic Acid; Embryo, Mammalian; Enzyme Inhibitors; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Phenylethyl Alcohol; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Time Factors

2005
Caffeic acid phenethyl ester (CAPE) prevents transformation of human cells by arsenite (As) and suppresses growth of As-transformed cells.
    Toxicology, 2005, Sep-15, Volume: 213, Issue:1-2

    Topics: Antioxidants; Apoptosis; Arsenites; Caffeic Acids; Catechin; Cell Growth Processes; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cytokines; Drug Interactions; Flow Cytometry; Humans; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Phenylethyl Alcohol; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes

2005
Antiarrhythmic effect of caffeic acid phenethyl ester (CAPE) on myocardial ischemia/reperfusion injury in rats.
    Clinical biochemistry, 2005, Volume: 38, Issue:10

    Topics: Animals; Anti-Arrhythmia Agents; Caffeic Acids; Male; Myocardial Reperfusion Injury; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Tachycardia, Ventricular; Ventricular Fibrillation

2005
Comparative analysis of the protective effects of melatonin and caffeic acid phenethyl ester (CAPE) on mobile phone-induced renal impairment in rat.
    Molecular and cellular biochemistry, 2005, Volume: 276, Issue:1-2

    Topics: Acetylglucosaminidase; Animals; Antioxidants; Caffeic Acids; Catalase; Cell Phone; Electromagnetic Fields; Glutathione Peroxidase; Kidney; Male; Malondialdehyde; Melatonin; Models, Animal; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2005
A novel antioxidant agent caffeic acid phenethyl ester prevents long-term mobile phone exposure-induced renal impairment in rat. Prognostic value of malondialdehyde, N-acetyl-beta-D-glucosaminidase and nitric oxide determination.
    Molecular and cellular biochemistry, 2005, Volume: 277, Issue:1-2

    Topics: Acetylglucosaminidase; Animals; Antioxidants; Caffeic Acids; Cell Phone; Electromagnetic Fields; Kidney; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Prognosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2005
Lithium-induced renal toxicity in rats: protection by a novel antioxidant caffeic acid phenethyl ester.
    Molecular and cellular biochemistry, 2005, Volume: 277, Issue:1-2

    Topics: Acetylglucosaminidase; Animals; Antioxidants; Blood Urea Nitrogen; Caffeic Acids; Catalase; Creatinine; Glutathione Peroxidase; Kidney; Lithium; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase

2005
The activities of purine-catabolizing enzymes and the level of nitric oxide in rat kidneys subjected to methotrexate: protective effect of caffeic acid phenethyl ester.
    Molecular and cellular biochemistry, 2005, Volume: 277, Issue:1-2

    Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Caffeic Acids; Folic Acid Antagonists; Free Radical Scavengers; Kidney; Male; Methotrexate; Nitric Oxide; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Xanthine Oxidase

2005
Effects of caffeic acid phenethyl ester on endotoxin-induced uveitis in rats.
    Current eye research, 2005, Volume: 30, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aqueous Humor; Caffeic Acids; Ciliary Body; Disease Models, Animal; Eye Proteins; Injections, Intraperitoneal; Iris; Lipopolysaccharides; Male; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Salmonella typhimurium; Uveitis

2005
Antiproliferation and radiosensitization of caffeic acid phenethyl ester on human medulloblastoma cells.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:4

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Astrocytes; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Cerebellar Neoplasms; Cisplatin; DNA Fragmentation; Doxorubicin; Drug Synergism; Humans; In Situ Nick-End Labeling; Medulloblastoma; Phenylethyl Alcohol; Radiation-Sensitizing Agents; Tumor Stem Cell Assay

2006
Effect of caffeic acid phenethyl ester on gastric acid secretion in vitro.
    European journal of pharmacology, 2005, Oct-03, Volume: 521, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcholinesterase; Animals; Caffeic Acids; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Gastrointestinal Agents; Histamine; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscarine; Nifedipine; Pentagastrin; Phenylethyl Alcohol; Physostigmine; Potassium; Stomach

2005
The selective inhibition of nitric oxide production in the avian macrophage cell line HD11.
    Veterinary immunology and immunopathology, 2006, Jan-15, Volume: 109, Issue:1-2

    Topics: Animals; Caffeic Acids; Cell Line; Chickens; Enterococcus; Enzyme Inhibitors; Genistein; I-kappa B Proteins; Klebsiella pneumoniae; Leupeptins; Macrophage Activation; Macrophages; NF-kappa B; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Poly I-C; Poultry Diseases; Protein-Tyrosine Kinases; RNA, Double-Stranded; Signal Transduction

2006
Inhibitory effects of caffeic acid phenethyl ester on cancer cell metastasis mediated by the down-regulation of matrix metalloproteinase expression in human HT1080 fibrosarcoma cells.
    The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:5

    Topics: Caffeic Acids; Cell Line, Tumor; Fibrosarcoma; Gene Expression Regulation, Enzymologic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Matrix Metalloproteinases, Membrane-Associated; Neoplasm Metastasis; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2

2006
Caffeic acid phenethyl ester possesses potent cardioprotective effects in a rabbit model of acute myocardial ischemia-reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:5

    Topics: Acute Disease; Animals; Apoptosis; Blotting, Western; Caffeic Acids; Cardiotonic Agents; Caspases; Creatine Kinase; Cytochromes c; In Situ Nick-End Labeling; Inflammation; Interleukin-1; L-Lactate Dehydrogenase; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Rabbits; Rats; Rats, Sprague-Dawley; Troponin I; Tumor Necrosis Factor-alpha

2005
Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells.
    British journal of pharmacology, 2005, Volume: 146, Issue:8

    Topics: Active Transport, Cell Nucleus; Anti-Inflammatory Agents; Caffeic Acids; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclooxygenase 2; Cytokines; DNA; Dose-Response Relationship, Drug; Epithelial Cells; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; I-kappa B Proteins; Membrane Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Time Factors; Transcription Factor AP-1; Transcription Factor RelA; Transcription, Genetic

2005
Caffeic acid phenethyl ester preferentially sensitizes CT26 colorectal adenocarcinoma to ionizing radiation without affecting bone marrow radioresponse.
    International journal of radiation oncology, biology, physics, 2005, Nov-15, Volume: 63, Issue:4

    Topics: Adenocarcinoma; Animals; Bone Marrow; Caffeic Acids; Cell Cycle; Colorectal Neoplasms; DNA Repair; Drug Evaluation, Preclinical; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Mice; Mice, Inbred BALB C; NF-kappa B; Phenylethyl Alcohol; Radiation-Sensitizing Agents

2005
In vivo effects of caffeic acid phenethyl ester on myocardial ischemia-reperfusion injury and apoptotic changes in rats.
    Annals of clinical and laboratory science, 2005,Autumn, Volume: 35, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Caffeic Acids; Cell Count; Coronary Disease; Creatine Kinase; Disease Models, Animal; Glutathione; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar

2005
Caffeic acid phenethyl ester ameliorates changes in IGFs secretion and gene expression in streptozotocin-induced diabetic rats.
    Life sciences, 2006, Mar-06, Volume: 78, Issue:15

    Topics: Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Gene Expression; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Kidney; Liver; Male; Myocardium; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley; RNA, Messenger

2006
Caffeic acid phenethyl ester ameliorates cerebral infarction in rats subjected to focal cerebral ischemia.
    Life sciences, 2006, May-01, Volume: 78, Issue:23

    Topics: Animals; Antioxidants; Blood Flow Velocity; Brain; Brain Ischemia; Caffeic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Long-Evans; Reperfusion Injury

2006
Protective effects of melatonin and caffeic acid phenethyl ester against retinal oxidative stress in long-term use of mobile phone: a comparative study.
    Molecular and cellular biochemistry, 2006, Volume: 282, Issue:1-2

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Cell Phone; Electromagnetic Fields; Free Radical Scavengers; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Retina; Superoxide Dismutase

2006
The activity of adenosine deaminase and the level of nitric oxide in spinal cord of methotrexate administered rats: protective effect of caffeic acid phenethyl ester.
    Toxicology, 2006, Feb-01, Volume: 218, Issue:2-3

    Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antioxidants; Antirheumatic Agents; Caffeic Acids; Male; Methotrexate; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Spinal Cord

2006
Caffeic acid phenethyl ester decreases acute pneumonitis after irradiation in vitro and in vivo.
    BMC cancer, 2005, Dec-09, Volume: 5

    Topics: Animals; Antioxidants; Caffeic Acids; Fibroblasts; Humans; Inflammation; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Radiation Pneumonitis; Tumor Cells, Cultured

2005
Mobile phone-induced myocardial oxidative stress: protection by a novel antioxidant agent caffeic acid phenethyl ester.
    Toxicology and industrial health, 2005, Volume: 21, Issue:9

    Topics: Animals; Antioxidants; Caffeic Acids; Cell Phone; Heart; Male; Myocardium; Oxidative Stress; Phenylethyl Alcohol; Radiation Injuries, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2005
Role of vagal activity on bradicardic and hypotensive effects of caffeic acid phenethyl ester (CAPE).
    Cardiovascular toxicology, 2005,Fall, Volume: 5, Issue:4

    Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Bradycardia; Caffeic Acids; Disease Models, Animal; Male; Muscarinic Antagonists; Parasympathetic Nervous System; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Vagotomy; Vagus Nerve

2005
Caffeic acid phenethyl ester (CAPE) attenuates cerebral vasospasm after experimental subarachnoidal haemorrhage by increasing brain nitric oxide levels.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2006, Volume: 24, Issue:1

    Topics: Animals; Basilar Artery; Brain; Caffeic Acids; Free Radical Scavengers; Glutathione; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar; Subarachnoid Hemorrhage; Vasospasm, Intracranial

2006
Altered iron homeostasis involvement in arsenite-mediated cell transformation.
    Free radical biology & medicine, 2006, Feb-01, Volume: 40, Issue:3

    Topics: Antioxidants; Arsenites; Caffeic Acids; Cell Transformation, Neoplastic; Cytoplasm; Ferritins; Homeostasis; Humans; Iron; Iron-Regulatory Proteins; Osteosarcoma; Oxidative Stress; Phenylethyl Alcohol; Receptors, Transferrin; Tumor Cells, Cultured

2006
Direct and indirect mechanism(s) of antitumour activity of propolis and its polyphenolic compounds.
    Planta medica, 2006, Volume: 72, Issue:1

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; DNA; Female; Femur; HeLa Cells; Humans; Leukocyte Count; Macrophage Activation; Male; Mice; Mice, Inbred CBA; Mitogens; Nitric Oxide; Phenylethyl Alcohol; Propolis; Spleen

2006
Lithium-induced lung toxicity in rats: the effect of caffeic acid phenethyl ester (CAPE).
    Pathology, 2006, Volume: 38, Issue:1

    Topics: Animals; Antioxidants; Caffeic Acids; Cell Movement; Injections, Intraperitoneal; Lithium; Lung; Lung Diseases; Lymphocytes; Macrophages, Alveolar; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar

2006
Oxidative stress in testicular tissues of rats exposed to cigarette smoke and protective effects of caffeic acid phenethyl ester.
    Asian journal of andrology, 2006, Volume: 8, Issue:2

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Glutathione Peroxidase; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Smoking; Superoxide Dismutase; Testis

2006
Does propofol or caffeic acid phenethyl ester prevent lung injury after hindlimb ischaemia-reperfusion in ventilated rats?
    Injury, 2006, Volume: 37, Issue:5

    Topics: Animals; Caffeic Acids; Free Radical Scavengers; Hindlimb; Ischemia; Lung; Lung Diseases; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Positive-Pressure Respiration; Propofol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome

2006
Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis.
    Cancer letters, 2007, Jan-08, Volume: 245, Issue:1-2

    Topics: Apoptosis; Blotting, Western; Caffeic Acids; Caspase 3; Caspase 8; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Breaks; DNA Fragmentation; DNA, Circular; Dose-Response Relationship, Drug; Flavonoids; Flow Cytometry; HL-60 Cells; Humans; Melanoma; Mitochondria; Molecular Structure; Phenylethyl Alcohol; Propolis; Reactive Oxygen Species; Signal Transduction; Xanthine Oxidase

2007
Effect of caffeic acid phenethyl ester on survival of axial pattern flaps in rats with ischaemia-reperfusion injuries.
    Scandinavian journal of plastic and reconstructive surgery and hand surgery, 2006, Volume: 40, Issue:2

    Topics: Animals; Antioxidants; Caffeic Acids; Graft Survival; Male; Nitrates; Nitrites; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Surgical Flaps

2006
Cytoprotective effect of caffeic acid phenethyl ester (CAPE) and catechol ring-fluorinated CAPE derivatives against menadione-induced oxidative stress in human endothelial cells.
    Bioorganic & medicinal chemistry, 2006, Jul-15, Volume: 14, Issue:14

    Topics: Antioxidants; Caffeic Acids; Cells, Cultured; Cytoprotection; Drug Evaluation, Preclinical; Endothelial Cells; Fluorine; Humans; Oxidative Stress; Phenylethyl Alcohol; Structure-Activity Relationship; Vitamin K 3

2006
The effect of caffeic acid phenethyl ester on short-term acute myocardial ischemia.
    Medical science monitor : international medical journal of experimental and clinical research, 2006, Volume: 12, Issue:5

    Topics: Acute Disease; Adenosine Deaminase; Animals; Antioxidants; Caffeic Acids; Cardiotonic Agents; Catalase; Glutathione Peroxidase; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase; Xanthine Oxidase

2006
Protective role of caffeic acid phenethyl ester in the liver of rats exposed to cold stress.
    Fundamental & clinical pharmacology, 2006, Volume: 20, Issue:3

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Cold Temperature; Female; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Malondialdehyde; Necrosis; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Stress, Physiological; Superoxide Dismutase

2006
Caffeic acid phenethyl ester blocks free radical generation and 6-hydroxydopamine-induced neurotoxicity.
    Life sciences, 2006, Aug-22, Volume: 79, Issue:13

    Topics: Animals; Animals, Newborn; Antioxidants; Caffeic Acids; Cell Death; Cerebellum; Free Radicals; Immunohistochemistry; In Vitro Techniques; Mesencephalon; Neurons; Neurotoxicity Syndromes; Oxidopamine; Peroxynitrous Acid; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Sympatholytics

2006
The activities of antioxidant enzymes and the level of malondialdehyde in cerebellum of rats subjected to methotrexate: protective effect of caffeic acid phenethyl ester.
    Molecular and cellular biochemistry, 2006, Volume: 291, Issue:1-2

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Cerebellum; Male; Malondialdehyde; Methotrexate; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase

2006
Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine.
    Molecular pain, 2006, Jun-09, Volume: 2

    Topics: Acetylcarnitine; Analgesics; Animals; Caffeic Acids; Cells, Cultured; Ganglia, Spinal; Gene Expression Regulation; Mice; Mice, Inbred ICR; Neurons, Afferent; NF-kappa B; Phenylethyl Alcohol; Proto-Oncogene Proteins c-rel; Receptors, Metabotropic Glutamate; RNA, Messenger; Transcription Factor RelA; Transcriptional Activation; Up-Regulation

2006
Enhancement of caffeic acid phenethyl ester on all-trans retinoic acid-induced differentiation in human leukemia HL-60 cells.
    Toxicology and applied pharmacology, 2006, Oct-01, Volume: 216, Issue:1

    Topics: Antineoplastic Agents; Blotting, Western; Caffeic Acids; CCAAT-Enhancer-Binding Proteins; CD11b Antigen; Cell Cycle; Cell Differentiation; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Lipopolysaccharide Receptors; Phenylethyl Alcohol; Receptors, Retinoic Acid; Receptors, TNF-Related Apoptosis-Inducing Ligand; Retinoic Acid Receptor alpha; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin

2006
Protective effects of caffeic acid phenethyl ester on skeletal muscle ischemia-reperfusion injury in rats.
    Molecular and cellular biochemistry, 2006, Volume: 292, Issue:1-2

    Topics: Adenosine Deaminase; Animals; Caffeic Acids; Creatine Kinase; Male; Muscle, Skeletal; Peroxidase; Phenylethyl Alcohol; Protein Carbonylation; Rats; Rats, Wistar; Reperfusion Injury; Xanthine Oxidase

2006
Role of caffeic acid phenethyl ester, an active component of propolis, against NAOH-induced esophageal burns in rats.
    International journal of pediatric otorhinolaryngology, 2006, Volume: 70, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Burns, Chemical; Caffeic Acids; Caustics; Esophageal Stenosis; Esophagus; Hydroxyproline; Lipid Peroxidation; Male; Malondialdehyde; Phenylethyl Alcohol; Propolis; Random Allocation; Rats; Rats, Wistar; Sodium Hydroxide

2006
The interleukin 1beta-induced expression of human prostaglandin F2alpha receptor messenger RNA in human myometrial-derived ULTR cells requires the transcription factor, NFkappaB.
    Biology of reproduction, 2006, Volume: 75, Issue:5

    Topics: Caffeic Acids; Cell Line; Cell Nucleus; Female; Humans; Interleukin-1beta; Leupeptins; Myometrium; NF-kappa B; Phenylethyl Alcohol; Proteasome Inhibitors; Receptors, Prostaglandin; Response Elements; RNA, Messenger; Transcription Factor RelA

2006
The effect of caffeic acid phenethyl ester (CAPE) on histopathological changes in testicular ischemia-reperfusion injury.
    Pharmacological research, 2006, Volume: 54, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caffeic Acids; Immunohistochemistry; Injections, Intraperitoneal; Male; Nitric Oxide Synthase Type II; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion Injury; Spermatic Cord Torsion; Testis

2006
Changes in membrane cholesterol of pituitary tumor (GH3) cells regulate the activity of large-conductance Ca2+-activated K+ channels.
    The Chinese journal of physiology, 2006, Feb-28, Volume: 49, Issue:1

    Topics: Action Potentials; Animals; Apamin; beta-Cyclodextrins; Caffeic Acids; Calcium; Cholesterol; Cilostazol; Dexamethasone; Diazoxide; Glyburide; Indoles; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Membrane Lipids; Phenylethyl Alcohol; Pituitary Neoplasms; Rats; Tetrazoles; Tumor Cells, Cultured

2006
Methotrexate-induced renal oxidative stress in rats: the role of a novel antioxidant caffeic acid phenethyl ester.
    Toxicology and industrial health, 2006, Volume: 22, Issue:6

    Topics: Animals; Caffeic Acids; Catalase; Free Radical Scavengers; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Methotrexate; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase

2006
Caffeic acid phenethyl ester induces growth arrest and apoptosis of colon cancer cells via the beta-catenin/T-cell factor signaling.
    Anti-cancer drugs, 2006, Volume: 17, Issue:7

    Topics: Annexin A5; Apoptosis; beta Catenin; Blotting, Western; Caffeic Acids; Cell Cycle; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Cyclin D1; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Genes, myc; Genes, Reporter; Humans; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection

2006
Inhibitory effect of caffeic acid phenethyl ester on the growth of SW480 colorectal tumor cells involves beta-catenin associated signaling pathway down-regulation.
    World journal of gastroenterology, 2006, Aug-21, Volume: 12, Issue:31

    Topics: Animals; Apoptosis; beta Catenin; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; Humans; Phenylethyl Alcohol; Signal Transduction; Tetrazolium Salts; Thiazoles

2006
Caffeic acid phenethyl ester modifies the Th1/Th2 balance in ileal mucosa after gamma-irradiation in the rat by modulating the cytokine pattern.
    World journal of gastroenterology, 2006, Aug-21, Volume: 12, Issue:31

    Topics: Animals; Apoptosis; Caffeic Acids; Caspase 3; CD4-Positive T-Lymphocytes; Cytokines; Gamma Rays; Ileum; Intestinal Mucosa; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Th1 Cells; Th2 Cells; Time Factors

2006
Caffeic acid phenethyl ester prevents cadmium-induced cardiac impairment in rat.
    Toxicology, 2006, Oct-03, Volume: 227, Issue:1-2

    Topics: Animals; Antioxidants; Cadmium Chloride; Caffeic Acids; Heart Diseases; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar

2006
Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-kappaB in cardiomyocytes.
    Cardiovascular research, 2006, Nov-01, Volume: 72, Issue:2

    Topics: Animals; Animals, Newborn; Aorta; Caffeic Acids; Constriction, Pathologic; Heart Failure; Hypertrophy, Left Ventricular; Indoles; Models, Animal; Myocytes, Cardiac; Natriuretic Peptide, Brain; NF-kappa B; Phenylethyl Alcohol; Quinolines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; RNA Interference; RNA, Small Interfering; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Stress, Mechanical; Ventricular Remodeling

2006
Ameliorating role of caffeic acid phenethyl ester (CAPE) against isoniazid-induced oxidative damage in red blood cells.
    Molecular and cellular biochemistry, 2006, Volume: 290, Issue:1-2

    Topics: Animals; Antioxidants; Antitubercular Agents; Caffeic Acids; Erythrocytes; Isoniazid; Male; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2006
Discoidin domain receptor 1 contributes to eosinophil survival in an NF-kappaB-dependent manner in Churg-Strauss syndrome.
    Blood, 2007, Jan-01, Volume: 109, Issue:1

    Topics: Adult; Aged; Apoptosis; Caffeic Acids; Cell Line; Cell Survival; Churg-Strauss Syndrome; Collagen; Cytokines; Discoidin Domain Receptor 1; Eosinophils; Female; Gene Expression Regulation; Humans; Kidney; Male; Middle Aged; NF-kappa B; Phenylethyl Alcohol; Protein Isoforms; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering

2007
Influence of electromagnetic fields and protective effect of CAPE on bone mineral density in rats.
    Archives of medical research, 2006, Volume: 37, Issue:7

    Topics: Animals; Bone Density; Caffeic Acids; Cell Phone; Electromagnetic Fields; Femur; Male; Phenylethyl Alcohol; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiography; Rats; Rats, Sprague-Dawley; Spine

2006
The effect of caffeic acid phenethyl ester on bacterial translocation and intestinal damage in cholestatic rats.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:10

    Topics: Animals; Bacterial Translocation; Caffeic Acids; Cholestasis, Extrahepatic; Enterobacteriaceae; Ileum; Liver; Lymph Nodes; Male; Mesentery; Phenylethyl Alcohol; Rats; Rats, Wistar; Staphylococcus aureus

2006
Caffeic acid phenethyl ester suppresses oxidative stress in Escherichia coli-induced pyelonephritis in rats.
    Molecular and cellular biochemistry, 2007, Volume: 297, Issue:1-2

    Topics: Animals; Caffeic Acids; Catalase; Escherichia coli; Glutathione Peroxidase; Inflammation; Kidney; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Pyelonephritis; Rats; Rats, Wistar; Superoxide Dismutase; Xanthine Oxidase

2007
Carrageenan induces interleukin-8 production through distinct Bcl10 pathway in normal human colonic epithelial cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Animals; B-Cell CLL-Lymphoma 10 Protein; Caffeic Acids; Carrageenan; Cell Line; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; Humans; I-kappa B Proteins; Interleukin-8; Intestinal Mucosa; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylethyl Alcohol; Phosphorylation; Promoter Regions, Genetic; Rats; RNA, Small Interfering; Signal Transduction; Transfection

2007
A single dose of caffeic acid phenethyl ester prevents initiation in a medium-term rat hepatocarcinogenesis model.
    World journal of gastroenterology, 2006, Nov-14, Volume: 12, Issue:42

    Topics: 2-Acetylaminofluorene; Animals; Caffeic Acids; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Cytotoxins; Diethylnitrosamine; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Glutathione S-Transferase pi; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; RNA, Messenger

2006
Combined therapy of teicoplanin and caffeic acid phenethyl ester (CAPE) in the treatment of experimental mediastinitis in the rat.
    Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Mediastinitis; Methicillin Resistance; Osteomyelitis; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin

2006
A preliminary study of the levels of testis oxidative stress parameters after MK-801-induced experimental psychosis model: protective effects of CAPE.
    Toxicology, 2007, Jan-25, Volume: 230, Issue:1

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Lipid Peroxidation; Male; Malondialdehyde; Nerve Tissue Proteins; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Paraffin Embedding; Phenylethyl Alcohol; Protein Denaturation; Psychoses, Substance-Induced; Rats; Rats, Wistar; Seminiferous Tubules; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Testis; Thiobarbituric Acid Reactive Substances

2007
Bifunctional alkylating agent-induced p53 and nonclassical nuclear factor kappaB responses and cell death are altered by caffeic acid phenethyl ester: a potential role for antioxidant/electrophilic response-element signaling.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1

    Topics: Alkylating Agents; Antioxidants; Blotting, Western; Caffeic Acids; Cell Death; Electrophoresis, Polyacrylamide Gel; Genes, p53; Genes, Reporter; Humans; Keratinocytes; L-Lactate Dehydrogenase; Luciferases; Mechlorethamine; Mustard Gas; NF-kappa B; Phenylethyl Alcohol; Receptors, Aryl Hydrocarbon; Response Elements; Signal Transduction; Transfection

2007
Attenuation of oxidative stress in plasma and tissues of rats with experimentally induced hyperthyroidism by caffeic acid phenylethyl ester.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Caffeic Acids; Glutathione; Glutathione Disulfide; Hyperthyroidism; Liver; Male; Myocardium; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Thyrotropin; Thyroxine; Triiodothyronine

2007
Antifungal chemical compounds identified using a C. elegans pathogenicity assay.
    PLoS pathogens, 2007, Volume: 3, Issue:2

    Topics: Animals; Antifungal Agents; Biofilms; Caenorhabditis elegans; Caffeic Acids; Candida; Enoxacin; Female; Fluconazole; Intestines; Mice; Mice, Inbred BALB C; Naphthoquinones; NF-kappa B; Phenylethyl Alcohol

2007
Stability of caffeic acid phenethyl ester and its fluorinated derivative in rat plasma.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:4

    Topics: Animals; Caffeic Acids; Chromatography, High Pressure Liquid; Drug Stability; Fluorine; Hydrogen-Ion Concentration; Phenylethyl Alcohol; Rats; Sodium Fluoride; Temperature

2007
Oxidative stress in prefrontal cortex of rat exposed to MK-801 and protective effects of CAPE.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, May-09, Volume: 31, Issue:4

    Topics: Animals; Behavior, Animal; Brain Chemistry; Caffeic Acids; Cytotoxins; Dizocilpine Maleate; Drug Interactions; Male; Neuroprotective Agents; Oxidative Stress; Phenylethyl Alcohol; Prefrontal Cortex; Protein Carbonylation; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances

2007
In vitro and in vivo stability of caffeic acid phenethyl ester, a bioactive compound of propolis.
    Journal of agricultural and food chemistry, 2007, May-02, Volume: 55, Issue:9

    Topics: Animals; Caffeic Acids; Chlorogenic Acid; Cinnamates; Depsides; Drug Stability; Humans; Hydrolysis; Phenylethyl Alcohol; Propolis; Rats; Rosmarinic Acid

2007
Beneficial effects of caffeic acid phenethyl ester (CAPE) on the ischaemia-reperfusion injury in rat skin flaps.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2007, Volume: 60, Issue:5

    Topics: Animals; Antioxidants; Caffeic Acids; Drug Evaluation, Preclinical; Female; Glutathione; Glutathione Peroxidase; Injections, Intraperitoneal; Malondialdehyde; Necrosis; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Surgical Flaps

2007
Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia.
    Journal of neurochemistry, 2007, Volume: 102, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Caffeic Acids; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Inflammation Mediators; Ischemic Attack, Transient; Male; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome

2007
Protective effects of caffeic acid phenethyl ester, vitamin C, vitamin E and N-acetylcysteine on vancomycin-induced nephrotoxicity in rats.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:5

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Blood Urea Nitrogen; Caffeic Acids; Catalase; Disease Models, Animal; Drinking; Drug Combinations; Injections, Intramuscular; Injections, Intraperitoneal; Kidney; Kidney Diseases; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Vancomycin; Vitamin E; Water Supply

2007
Drastic effect of several caffeic acid derivatives on the induction of heme oxygenase-1 expression revealed by quantitative real-time RT-PCR.
    BioFactors (Oxford, England), 2006, Volume: 28, Issue:3-4

    Topics: Animals; Caffeic Acids; Cell Line; Cell Line, Tumor; Enzyme Induction; Heme Oxygenase-1; Humans; Mice; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2006
The effect of caffeic acid phenethyl ester on the prevention of experimentally induced myringosclerosis.
    International journal of pediatric otorhinolaryngology, 2007, Volume: 71, Issue:8

    Topics: Animals; Caffeic Acids; Male; NF-kappa B; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Sprague-Dawley; Sclerosis; Tympanic Membrane

2007
Characterization of a novel and potent collagen antagonist, caffeic acid phenethyl ester, in human platelets: in vitro and in vivo studies.
    Cardiovascular research, 2007, Sep-01, Volume: 75, Issue:4

    Topics: Animals; Biological Assay; Blood Platelets; Caffeic Acids; Collagen; Crotalid Venoms; Depression, Chemical; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Hydroxyl Radical; Immunoblotting; Integrin alpha2beta1; Lectins, C-Type; Mesenteric Arteries; Mice; Phenylethyl Alcohol; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Spectrometry, Fluorescence; Thrombosis; Thromboxane B2; Viper Venoms

2007
Effect of caffeic acid phenethyl ester on the regression of endometrial explants in an experimental rat model.
    Reproductive sciences (Thousand Oaks, Calif.), 2007, Volume: 14, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caffeic Acids; Catalase; Cyclooxygenase 2; Disease Models, Animal; Endometriosis; Endometrium; Female; Lipid Peroxidation; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Wistar; Statistics, Nonparametric; Superoxide Dismutase; Transplantation, Autologous; Uterus

2007
The neuroprotective effects of caffeic acid phenethyl ester (CAPE) in the hippocampal formation of cigarette smoke exposed rabbits.
    Pathology, 2007, Volume: 39, Issue:4

    Topics: Animals; Apoptosis; Caffeic Acids; DNA Damage; Hippocampus; Injections, Intraperitoneal; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Nicotiana; Phenylethyl Alcohol; Rabbits; Reactive Oxygen Species; Smoke; Superoxide Dismutase

2007
CAPE (caffeic acid phenethyl ester) stimulates glucose uptake through AMPK (AMP-activated protein kinase) activation in skeletal muscle cells.
    Biochemical and biophysical research communications, 2007, Oct-05, Volume: 361, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Biological Transport; Caffeic Acids; Cell Differentiation; Cell Line; Enzyme Activation; Glucose; Multienzyme Complexes; Muscle Fibers, Skeletal; Myoblasts; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats

2007
N-acetyl cysteine and caffeic acid phenethyl ester sensitize astrocytoma cells to Fas-mediated cell death in a redox-dependent manner.
    Cancer letters, 2007, Nov-08, Volume: 257, Issue:1

    Topics: Acetylcysteine; Astrocytoma; Caffeic Acids; Caspase Inhibitors; Caspases; Cell Death; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Humans; Membrane Potentials; Mitochondrial Membranes; Models, Biological; Oxidation-Reduction; Phenylethyl Alcohol; Reactive Oxygen Species; Time Factors

2007
Effects of caffeic acid phenethyl ester on the histopathological changes in the lungs of cigarette smoke-exposed rabbits.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 101, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Inflammation; Lung; Male; Nicotiana; Phenylethyl Alcohol; Rabbits; Smoke

2007
Regulation of monocarboxylate transporter 1 (MCT1) promoter by butyrate in human intestinal epithelial cells: involvement of NF-kappaB pathway.
    Journal of cellular biochemistry, 2008, Apr-01, Volume: 103, Issue:5

    Topics: Butyrates; Caco-2 Cells; Caffeic Acids; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Humans; Intestinal Mucosa; Monocarboxylic Acid Transporters; NF-kappa B; Phenylethyl Alcohol; Protein Kinase C; Response Elements; Signal Transduction; Substrate Specificity; Symporters

2008
Protein phosphatase 2A (PP2A) has a potential role in CAPE-induced apoptosis of CCRF-CEM cells via effecting human telomerase reverse transcriptase activity.
    Hematology (Amsterdam, Netherlands), 2007, Volume: 12, Issue:6

    Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Phenylethyl Alcohol; Protein Phosphatase 2; Telomerase

2007
Antiplatelet activity of caffeic acid phenethyl ester is mediated through a cyclic GMP-dependent pathway in human platelets.
    The Chinese journal of physiology, 2007, Jun-30, Volume: 50, Issue:3

    Topics: Blood Platelets; Caffeic Acids; Cell Adhesion Molecules; Cyclic AMP; Cyclic GMP; Humans; Microfilament Proteins; Phenylethyl Alcohol; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Thromboembolism

2007
Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis.
    Toxicology and applied pharmacology, 2008, Jan-01, Volume: 226, Issue:1

    Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Caffeic Acids; Disease Models, Animal; Female; Histamine Release; Immunoglobulin E; Mice; Mice, Inbred ICR; NF-kappa B; Ovalbumin; Phenylethyl Alcohol; Tumor Necrosis Factor-alpha

2008
Cytotoxicity of NF-kappaB inhibitors Bay 11-7085 and caffeic acid phenethyl ester to Ramos and other human B-lymphoma cell lines.
    Experimental hematology, 2007, Volume: 35, Issue:10

    Topics: Active Transport, Cell Nucleus; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytoplasm; Cytotoxins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lymphoma, B-Cell; Membrane Potential, Mitochondrial; Necrosis; Nitriles; Phenylethyl Alcohol; Protein Binding; Sulfones; Time Factors; Transcription Factor RelA

2007
Antibacterial and free-radical scavenging activities of Sonoran propolis.
    Journal of applied microbiology, 2007, Volume: 103, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Bees; Butylated Hydroxytoluene; Caffeic Acids; Flavones; Flavonols; Food Microbiology; Free Radical Scavengers; Gram-Positive Bacteria; Mexico; Microbial Sensitivity Tests; Phenols; Phenylethyl Alcohol; Propolis; Rutin; Staphylococcus aureus; Vitamins

2007
Caffeic acid phenethyl ester accelerates cutaneous wound healing in a rat model and decreases oxidative stress.
    Clinical and experimental dermatology, 2007, Volume: 32, Issue:6

    Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Glutathione; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Reactive Oxygen Species; Skin; Superoxide Dismutase; Wound Healing

2007
The effects of caffeic acid phenethyl ester (CAPE) on TNBS-induced colitis in ovariectomized rats.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:6

    Topics: Animals; Caffeic Acids; Catalase; Colitis; Female; Glutathione; Malondialdehyde; Ovary; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Statistics, Nonparametric; Trinitrobenzenesulfonic Acid

2008
N-acetylcysteine stimulates osteoblastic differentiation of mouse calvarial cells.
    Journal of cellular biochemistry, 2008, Mar-01, Volume: 103, Issue:4

    Topics: Acetylcysteine; Alkaline Phosphatase; Animals; Antioxidants; Bacterial Proteins; Bacterial Toxins; Bone Morphogenetic Proteins; Caffeic Acids; Cell Differentiation; Cells, Cultured; Glutathione; Mice; Osteoblasts; Osteogenesis; Phenylethyl Alcohol; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Skull

2008
Effects of caffeic acid phenethyl ester on pancreatitis in rats.
    The Journal of surgical research, 2008, Volume: 145, Issue:1

    Topics: Alanine Transaminase; Animals; Antioxidants; Bacterial Translocation; Bronchoalveolar Lavage Fluid; Caffeic Acids; Detergents; Disease Models, Animal; Glycodeoxycholic Acid; L-Lactate Dehydrogenase; Lung; Male; Malondialdehyde; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2008
Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kappa B signaling in urothelial cancer cells.
    Cancer investigation, 2007, Volume: 25, Issue:8

    Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Chromones; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Morpholines; Neoplasm Proteins; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Survivin; Transfection; Urinary Bladder Neoplasms

2007
Caffeic acid phenethyl ester induces mitochondria-mediated apoptosis in human myeloid leukemia U937 cells.
    Molecular and cellular biochemistry, 2008, Volume: 310, Issue:1-2

    Topics: Apoptosis; Caffeic Acids; Caspase 3; Cell Line, Tumor; Chromatin; Cytochromes c; DNA Fragmentation; Endoplasmic Reticulum; Eukaryotic Initiation Factor-2; fas Receptor; Humans; Leukemia, Myeloid; Mitochondria; Phenylethyl Alcohol; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Receptors, Death Domain; Transcription Factor CHOP; U937 Cells

2008
Caffeic acid phenethyl ester reduces mortality and sepsis-induced lung injury in rats.
    Critical care medicine, 2007, Volume: 35, Issue:12

    Topics: Animals; Apoptosis; Caffeic Acids; Cytokines; Female; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Sepsis; Survival Analysis

2007
Differential regulation of c-Jun N-terminal kinase and NF-kappaB pathway by caffeic acid phenethyl ester in astroglial and monocytic cells.
    Journal of neurochemistry, 2008, Volume: 105, Issue:2

    Topics: Astrocytes; Caffeic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fetus; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; JNK Mitogen-Activated Protein Kinases; Models, Biological; Monocytes; NF-kappa B; Phenylethyl Alcohol; Signal Transduction; Tumor Necrosis Factor-alpha

2008
Caffeic acid phenethyl ester and its related compounds limit the functional alterations of the isolated mouse brain and liver mitochondria submitted to in vitro anoxia-reoxygenation: relationship to their antioxidant activities.
    Biochimica et biophysica acta, 2008, Volume: 1780, Issue:4

    Topics: Anaerobiosis; Animals; Anisotropy; Antioxidants; Brain; Caffeic Acids; Coumaric Acids; Cytochromes c; Dose-Response Relationship, Drug; Male; Mice; Mitochondria; Mitochondria, Liver; Mitochondrial Membranes; Molecular Structure; Oxygen; Phenylethyl Alcohol; Thiobarbituric Acid Reactive Substances

2008
DNA damage induced by caffeic acid phenyl ester in the presence of Cu(II) ions: potential mechanism of its anticancer properties.
    Cancer letters, 2008, May-08, Volume: 263, Issue:1

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Catalase; Cattle; Copper; DNA; DNA Damage; Edetic Acid; Electrophoresis, Agar Gel; Free Radical Scavengers; Phenylethyl Alcohol; Reactive Oxygen Species; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

2008
Caffeic acid phenethyl ester (CAPE) protects brain against oxidative stress and inflammation induced by diabetes in rats.
    Molecular and cellular biochemistry, 2008, Volume: 312, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Caffeic Acids; Cytokines; Cytoprotection; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Encephalitis; Gene Expression Regulation; Lipid Peroxidation; Male; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Streptozocin

2008
Caffeic acid phenethyl ester attenuates allergic airway inflammation and hyperresponsiveness in murine model of ovalbumin-induced asthma.
    Life sciences, 2008, Mar-26, Volume: 82, Issue:13-14

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Caffeic Acids; Cell Count; Cytokines; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Peroxides; Phenylethyl Alcohol; Respiratory Hypersensitivity

2008
Caffeic acid phenethyl ester protects rabbit brains against permanent focal ischemia by antioxidant action: a biochemical and planimetric study.
    Brain research, 2008, Mar-27, Volume: 1201

    Topics: Animals; Antioxidants; Biomarkers; Brain Infarction; Brain Ischemia; Brain Mapping; Caffeic Acids; Catalase; Enzyme Inhibitors; Glutathione; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rabbits; Spectrophotometry; Treatment Outcome; Xanthine Oxidase

2008
Leishmania major infection activates NF-kappaB and interferon regulatory factors 1 and 8 in human dendritic cells.
    Infection and immunity, 2008, Volume: 76, Issue:5

    Topics: Animals; Binding Sites; Caffeic Acids; Cells, Cultured; Dendritic Cells; DNA; Gene Expression Profiling; Humans; Immunologic Factors; Interferon Regulatory Factor-1; Interferon Regulatory Factors; Interleukin-12; Leishmania major; NF-kappa B; Phenylethyl Alcohol; Promoter Regions, Genetic; Protein Binding; Up-Regulation

2008
Quantitative determination of fluorinated caffeic acid phenethyl ester derivative from rat blood plasma by liquid chromatography-electrospray ionization tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, May-01, Volume: 867, Issue:1

    Topics: Animals; Caffeic Acids; Chromatography, Liquid; Fluorine; Male; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2008
Evidence that the anticarcinogenic effect of caffeic acid phenethyl ester in the resistant hepatocyte model involves modifications of cytochrome P450.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 104, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Anticarcinogenic Agents; Caffeic Acids; Cytochrome P-450 Enzyme System; Diethylnitrosamine; gamma-Glutamyltransferase; Hepatocytes; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Phenylethyl Alcohol; Rats; Rats, Inbred F344

2008
Potential cytoprotection: antioxidant defence by caffeic acid phenethyl ester against free radical-induced damage of lipids, DNA, and proteins.
    Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:5

    Topics: Adult; Amidines; Antioxidants; Caffeic Acids; Comet Assay; Cytoprotection; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Erythrocyte Membrane; Humans; Hydrogen Peroxide; Lipid Peroxidation; Male; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Protein Carbonylation; Reactive Oxygen Species; Structure-Activity Relationship; Time Factors

2008
Protective effect of caffeic acid phenethyl ester against carbon tetrachloride-induced hepatotoxicity in mice.
    Toxicology, 2008, Jun-03, Volume: 248, Issue:1

    Topics: Animals; Caffeic Acids; Carbon Tetrachloride; Caspase 3; Caspase 8; Catalase; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Fas Ligand Protein; fas Receptor; Glutathione Transferase; Liver Diseases; Male; Mice; Mice, Inbred ICR; Phenylethyl Alcohol; Protective Agents; Solvents; Superoxide Dismutase

2008
Caffeic acid phenethyl ester preferentially enhanced radiosensitizing and increased oxidative stress in medulloblastoma cell line.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2008, Volume: 24, Issue:9

    Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Glutathione; Humans; In Situ Nick-End Labeling; Medulloblastoma; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Radiation-Sensitizing Agents; Reactive Oxygen Species

2008
Protective effect of caffeic acid phenethyl ester on tert-butyl hydroperoxide-induced oxidative hepatotoxicity and DNA damage.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Caffeic Acids; Cell Line, Tumor; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Lipid Peroxidation; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; tert-Butylhydroperoxide

2008
Effects of propolis and CAPE on proliferation and apoptosis of McCoy-Plovdiv cell line.
    Folia medica, 2008, Volume: 50, Issue:1

    Topics: Apoptosis; Caffeic Acids; Cell Line; Cell Proliferation; Comet Assay; DNA Damage; Fibroblasts; Humans; Immunohistochemistry; Phenylethyl Alcohol; Proliferating Cell Nuclear Antigen; Propolis; Synovial Membrane; Tumor Suppressor Protein p53

2008
Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-kappaB pathways.
    The international journal of biochemistry & cell biology, 2008, Volume: 40, Issue:11

    Topics: Animals; Caffeic Acids; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Shock, Septic; Signal Transduction; Tumor Necrosis Factor-alpha

2008
Cytoprotection of human endothelial cells from menadione cytotoxicity by caffeic acid phenethyl ester: the role of heme oxygenase-1.
    European journal of pharmacology, 2008, Sep-04, Volume: 591, Issue:1-3

    Topics: Antioxidants; Blotting, Western; Caffeic Acids; Carbon Monoxide; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Heme Oxygenase-1; Humans; Oxidative Stress; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; Umbilical Veins; Up-Regulation; Vitamin K 3

2008
New anti-inflammatory 4-methylated steroids from the Formosan soft coral Nephthea chabroli.
    Steroids, 2008, Volume: 73, Issue:11

    Topics: Animals; Anthozoa; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Cell Line; Cyclooxygenase 2; Enzyme Inhibitors; Lipopolysaccharides; Macrophage Activation; Macrophages; Methylation; Mice; Molecular Conformation; Molecular Structure; Nitric Oxide Synthase Type II; Nuclear Magnetic Resonance, Biomolecular; Phenylethyl Alcohol; Reference Standards; Spectrophotometry, Infrared; Steroids; Up-Regulation

2008
Effects of caffeic acid phenethyl ester (CAPE) on sepsis in rats.
    Inflammation, 2008, Volume: 31, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bronchoalveolar Lavage Fluid; Caffeic Acids; Inflammation Mediators; Infusions, Parenteral; Kidney; L-Lactate Dehydrogenase; Liver; Lung; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Sepsis

2008
Inhibitory effect of caffeic acid phenethyl ester (CAPE) on LPS-induced inflammation of human middle ear epithelial cells.
    Acta oto-laryngologica, 2008, Volume: 128, Issue:12

    Topics: Caffeic Acids; Cell Line; Gene Expression; Humans; Inflammation Mediators; Interleukin-8; Lipopolysaccharides; NF-kappa B; Otitis Media; Phenylethyl Alcohol; Tumor Necrosis Factor-alpha

2008
The protective effect of CAPE on hepatic ischemia/reperfusion injury in rats.
    The Journal of surgical research, 2008, Volume: 150, Issue:2

    Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Caffeic Acids; Glutathione; Lipid Peroxidation; Liver; Male; Neutrophils; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury

2008
Caffeic acid phenethyl ester prevents cerebellar granule neurons (CGNs) against glutamate-induced neurotoxicity.
    Neuroscience, 2008, Sep-09, Volume: 155, Issue:4

    Topics: Animals; Animals, Newborn; Caffeic Acids; Caspase 3; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Membrane Potentials; Mitochondria; Neurons; Neuroprotective Agents; Neurotoxins; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Phenylethyl Alcohol; Phosphorylation; Rats

2008
Protective effects of caffeic acid phenethyl ester on intestinal ischemia-reperfusion injury.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:4

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Glutathione; Glutathione Peroxidase; Intestinal Diseases; Intestinal Mucosa; Jejunum; Lipid Peroxidation; Male; Malondialdehyde; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2009
CAPE (caffeic acid phenethyl ester)-based propolis extract (Bio 30) suppresses the growth of human neurofibromatosis (NF) tumor xenografts in mice.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:2

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Female; Humans; Mice; Mice, Nude; Neurofibromatosis 1; Neurofibromatosis 2; p21-Activated Kinases; Phenylethyl Alcohol; Propolis; Xenograft Model Antitumor Assays

2009
Effect of NFkappaB inhibition by CAPE on skeletal muscle ischemia-reperfusion injury.
    The Journal of surgical research, 2009, May-15, Volume: 153, Issue:2

    Topics: Animals; Caffeic Acids; Male; Medicine, Traditional; Muscle, Skeletal; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury

2009
Caffeic acid phenethyl ester induces apoptosis of human pancreatic cancer cells involving caspase and mitochondrial dysfunction.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2008, Volume: 8, Issue:6

    Topics: Antioxidants; Apoptosis; Caffeic Acids; Caspases; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Membrane Potential, Mitochondrial; Mitochondria; Pancreatic Neoplasms; Phenylethyl Alcohol; Substrate Specificity; Time Factors

2008
Caffeic acid phenethyl ester modulates methotrexate-induced oxidative stress in testes of rat.
    Human & experimental toxicology, 2008, Volume: 27, Issue:7

    Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Caffeic Acids; Cytotoxins; Drug Antagonism; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Methotrexate; Organ Size; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase; Testis

2008
Zinc deficiency induces vascular pro-inflammatory parameters associated with NF-kappaB and PPAR signaling.
    Journal of the American College of Nutrition, 2008, Volume: 27, Issue:5

    Topics: Animals; Atherosclerosis; Caffeic Acids; Cell Adhesion; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation; Inflammation; Male; Mice; Monocytes; NF-kappa B; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Phenylethyl Alcohol; Receptors, LDL; Rosiglitazone; Thiazolidinediones; Zinc

2008
Protective effects of caffeic acid phenethyl ester on radiation induced lung injury in rats.
    Clinical and investigative medicine. Medecine clinique et experimentale, 2008, Oct-01, Volume: 31, Issue:5

    Topics: Animals; Antioxidants; Caffeic Acids; Gamma Rays; Lung; Lung Injury; Male; Malondialdehyde; Phenylethyl Alcohol; Radiation Injuries, Experimental; Rats; Superoxide Dismutase

2008
Artepillin C (ARC) in Brazilian green propolis selectively blocks oncogenic PAK1 signaling and suppresses the growth of NF tumors in mice.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:3

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Female; Mice; Mice, Nude; Neoplasms, Experimental; Neurofibromatoses; p21-Activated Kinases; Phenylethyl Alcohol; Phenylpropionates; Propolis; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays

2009
The effects of hydroxycinnamic acid derivatives on adiponectin secretion.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2009, Volume: 16, Issue:2-3

    Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Caffeic Acids; Coumaric Acids; Curcumin; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Phenylpropionates; Phytotherapy; Pioglitazone; Plant Extracts; Plant Oils; Rice Bran Oil; Thiazolidinediones; Tumor Necrosis Factor-alpha

2009
Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats.
    Toxicology and industrial health, 2008, Volume: 24, Issue:8

    Topics: Adenosine Deaminase; Administration, Oral; Animals; Antioxidants; Antitubercular Agents; Caffeic Acids; Disease Models, Animal; Drinking; Drug Therapy, Combination; Erythrocytes; Injections, Intraperitoneal; Isoniazid; Male; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Xanthine Oxidase

2008
Inhibition of human catechol-O-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee.
    The Journal of steroid biochemistry and molecular biology, 2009, Volume: 113, Issue:1-2

    Topics: Adult; Biocatalysis; Caffeic Acids; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Chlorogenic Acid; Coffee; Computational Biology; Cytosol; Estrogens, Catechol; Female; Flavonoids; Humans; Inhibitory Concentration 50; Kinetics; Liver; Methylation; Models, Molecular; Phenols; Phenylethyl Alcohol; Placenta; Polyphenols; Protein Binding; Protein Structure, Secondary

2009
Decreasing the expression of LFA-1 and ICAM-1 as the major mechanism for the protective effect of caffeic acid phenethyl ester on ischemia-reperfusion injury.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2009, Volume: 62, Issue:4

    Topics: Animals; Antioxidants; Caffeic Acids; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Phenylethyl Alcohol; Reperfusion Injury; Surgical Flaps

2009
Taurocholate feeding to bile duct ligated rats prevents caffeic acid-induced bile duct damage by changes in cholangiocyte VEGF expression.
    Experimental biology and medicine (Maywood, N.J.), 2009, Volume: 234, Issue:4

    Topics: Animals; Apoptosis; Bile; Bile Ducts; Caffeic Acids; Cell Proliferation; Cholagogues and Choleretics; Cytotoxins; Immunohistochemistry; Ligation; Male; Phenylethyl Alcohol; Rats; Rats, Inbred F344; Receptors, Vascular Endothelial Growth Factor; Taurocholic Acid; Vascular Endothelial Growth Factors

2009
Caffeic acid phenethyl ester (CAPE) ameliorates cisplatin-induced hepatotoxicity in rabbit.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2010, Volume: 62, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeic Acids; Cisplatin; Glutathione; Liver; Male; Malondialdehyde; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Phenylethyl Alcohol; Rabbits; Xanthine Oxidase

2010
Caffeic acid phenethyl ester inhibits osteoclastogenesis by suppressing NF kappaB and downregulating NFATc1 and c-Fos.
    International immunopharmacology, 2009, Volume: 9, Issue:6

    Topics: Animals; Bone Marrow; Caffeic Acids; Cell Differentiation; Cells, Cultured; Female; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Phenylethyl Alcohol; Proto-Oncogene Proteins c-fos; RANK Ligand

2009
Caffeic acid phenethyl ester accumulates beta-catenin through GSK-3beta and participates in proliferation through mTOR in C2C12 cells.
    Life sciences, 2009, May-22, Volume: 84, Issue:21-22

    Topics: Actins; Animals; beta Catenin; Blotting, Western; Caffeic Acids; Cell Line; Cell Proliferation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indicators and Reagents; Mice; Myoblasts; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Protein Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2009
Novel approach for the prevention of contrast nephropathy.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2010, Volume: 62, Issue:1

    Topics: Acetylcysteine; Animals; Caffeic Acids; Catalase; Contrast Media; Creatinine; Glutathione Peroxidase; Kidney; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Superoxide Dismutase

2010
Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF-kappaB and induction of apoptosis.
    International journal of cancer, 2009, Aug-01, Volume: 125, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biomarkers, Tumor; Caffeic Acids; Cell Cycle; Cholangiocarcinoma; Cytotoxins; Dimethyl Sulfoxide; DNA; Down-Regulation; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Liver; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Organ Size; Phenylethyl Alcohol; Proliferating Cell Nuclear Antigen; Signal Transduction; Transcription Factor RelA; Transplantation, Heterologous; Up-Regulation

2009
Inhibition of store-operated Ca2+ entry channels and K+ channels by caffeic acid phenethylester in T lymphocytes.
    European journal of pharmacology, 2009, Jun-10, Volume: 612, Issue:1-3

    Topics: Caffeic Acids; Calcium; Calcium Signaling; CD28 Antigens; CD3 Complex; Cell Line; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electrophysiology; Humans; Inositol 1,4,5-Trisphosphate; Interleukin-2; Ionomycin; Jurkat Cells; Kidney; Patch-Clamp Techniques; Phenylethyl Alcohol; Phytohemagglutinins; Potassium Channels, Voltage-Gated; T-Lymphocytes; Thapsigargin; Time Factors

2009
The use of FTIR microscopy for the evaluation of anti-bacterial agents activity.
    Journal of photochemistry and photobiology. B, Biology, 2009, Jul-17, Volume: 96, Issue:1

    Topics: Ampicillin; Anti-Bacterial Agents; Caffeic Acids; Gram-Negative Bacteria; Gram-Positive Bacteria; Phenylethyl Alcohol; Spectroscopy, Fourier Transform Infrared

2009
Caffeic acid phenethyl ester protects against tamoxifen-induced hepatotoxicity in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:7

    Topics: Animals; Antineoplastic Agents, Hormonal; Antioxidants; Caffeic Acids; Chemical and Drug Induced Liver Injury; Female; Glutathione; Lipid Peroxidation; Liver; Liver Function Tests; Neutrophils; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tamoxifen; Tumor Necrosis Factor-alpha; Xanthine Oxidase

2009
Caffeic acid phenethyl ester prevents ovary ischemia/reperfusion injury in rabbits.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:8

    Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Female; Glutathione; Lipid Peroxidation; Ovarian Diseases; Phenylethyl Alcohol; Rabbits; Reperfusion Injury; Thiobarbituric Acid Reactive Substances

2009
A short critique aimed to be constructive to authors, referees, and editors.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2010, Volume: 63, Issue:2

    Topics: Animals; Antioxidants; Caffeic Acids; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Phenylethyl Alcohol; Reperfusion Injury; Surgical Flaps

2010
The effect of caffeic acid phenethyl ester (CAPE) against cholestatic liver injury in rats.
    The Journal of surgical research, 2010, Volume: 159, Issue:2

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Caffeic Acids; Cholestasis; Cholestasis, Intrahepatic; gamma-Glutamyltransferase; Glutathione Transferase; Jaundice; Male; Malondialdehyde; Peroxidase; Phenylethyl Alcohol; Rats

2010
Pharmacokinetics of caffeic acid phenethyl ester and its catechol-ring fluorinated derivative following intravenous administration to rats.
    Biopharmaceutics & drug disposition, 2009, Volume: 30, Issue:5

    Topics: Animals; Area Under Curve; Caffeic Acids; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Half-Life; Injections, Intravenous; Male; Nonlinear Dynamics; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2009
Caffeic acid phenethyl ester decreases the level of S-100B protein after middle cerebral artery [correction for after] occlusion in rabbits.
    Pakistan journal of pharmaceutical sciences, 2009, Volume: 22, Issue:3

    Topics: Animals; Biomarkers; Brain Damage, Chronic; Caffeic Acids; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Male; Nerve Growth Factors; Neuroprotective Agents; Phenylethyl Alcohol; Rabbits; S100 Calcium Binding Protein beta Subunit; S100 Proteins

2009
The effect of caffeic acid phenethyl ester on the functions of human monocyte-derived dendritic cells.
    BMC immunology, 2009, Jul-16, Volume: 10

    Topics: Allergens; Animals; Caffeic Acids; Chemokine CXCL10; Dendritic Cells; Humans; Hypersensitivity; I-kappa B Kinase; Interleukin-10; Interleukin-12; Interleukin-12 Subunit p40; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Propolis; Pyroglyphidae; Signal Transduction; T-Lymphocytes

2009
Anti-inflammatory effects of caffeic acid phenethyl ester (CAPE), a nuclear factor-kappaB inhibitor, on Helicobacter pylori-induced gastritis in Mongolian gerbils.
    International journal of cancer, 2009, Oct-15, Volume: 125, Issue:8

    Topics: Animals; Blotting, Western; Caffeic Acids; Cytotoxins; Gastric Mucosa; Gastritis; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Immunoenzyme Techniques; Interferon-gamma; Interleukin-6; Interleukin-8; Male; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

2009
Influence of electromagnetic fields on bone fracture in rats: role of CAPE.
    Biomedical and environmental sciences : BES, 2009, Volume: 22, Issue:2

    Topics: Animals; Biomechanical Phenomena; Bone Density; Caffeic Acids; Electromagnetic Fields; Femur; Fractures, Bone; Male; Phenylethyl Alcohol; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley

2009
Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Caffeic Acids; Drug Design; HIV Integrase; HIV Integrase Inhibitors; Humans; Nitrogen; Phenylethyl Alcohol; Structure-Activity Relationship

2009
Caffeic acid phenethyl ester, a component of beehive propolis, is a novel selective estrogen receptor modulator.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:2

    Topics: Animals; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor alpha; Female; Humans; Phenylethyl Alcohol; Propolis; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Uterus

2010
Caffeic acid phenethyl ester, an active component of honeybee propolis attenuates osteoclastogenesis and bone resorption via the suppression of RANKL-induced NF-kappaB and NFAT activity.
    Journal of cellular physiology, 2009, Volume: 221, Issue:3

    Topics: Acid Phosphatase; Active Transport, Cell Nucleus; Animals; Apoptosis; Bone Resorption; Caffeic Acids; Caspase 3; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Humans; I-kappa B Proteins; Isoenzymes; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; NFATC Transcription Factors; Osteoclasts; Phenylethyl Alcohol; Propolis; RANK Ligand; Tartrate-Resistant Acid Phosphatase; Transcription Factor RelA; Tumor Cells, Cultured

2009
Caffeic acid phenethyl ester (CAPE) exhibits significant potential as an antidiabetic and liver-protective agent in streptozotocin-induced diabetic rats.
    Pharmacological research, 2009, Volume: 60, Issue:4

    Topics: Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Glucose; Hypoglycemic Agents; Liver; Male; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Streptozocin

2009
Caffeic acid phenethyl ester, an antioxidant from propolis, protects peripheral blood mononuclear cells of competitive cyclists against hyperthermal stress.
    Journal of food science, 2009, Volume: 74, Issue:6

    Topics: Antioxidants; Bicycling; Caffeic Acids; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Exercise Test; Glutathione; Hot Temperature; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Male; Necrosis; Phenylethyl Alcohol; Physical Fitness; Propolis; Stress, Physiological; Superoxides

2009
Caffeic acid phenethyl ester is a potent inhibitor of HIF prolyl hydroxylase: structural analysis and pharmacological implication.
    The Journal of nutritional biochemistry, 2010, Volume: 21, Issue:9

    Topics: Animals; Caffeic Acids; Cells, Cultured; Enzyme Inhibitors; HEK293 Cells; Heme Oxygenase-1; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Phenylethyl Alcohol; Procollagen-Proline Dioxygenase; Reperfusion Injury; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2010
The ultrastructural and biochemical evidences of the beneficial effects of chronic caffeic acid phenethyl ester and melatonin administration on brain and cerebellum of aged rats.
    Fundamental & clinical pharmacology, 2010, Volume: 24, Issue:3

    Topics: Aging; Animals; Brain; Caffeic Acids; Cerebellum; Cerebrum; Drug Administration Schedule; Male; Melatonin; Neurons; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2010
Efficacy of caffeic acid phenethyl ester (CAPE) in skin B16-F0 melanoma tumor bearing C57BL/6 mice.
    Investigational new drugs, 2011, Volume: 29, Issue:1

    Topics: Animals; Caffeic Acids; Cell Cycle; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glutathione; Hydrogen-Ion Concentration; Intracellular Space; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Oxidation-Reduction; Oxygen; Phenylethyl Alcohol; Reactive Oxygen Species; Skin Neoplasms; Spectrophotometry, Ultraviolet; Treatment Outcome

2011
Therapeutic effect of caffeic acid phenethyl ester on cerulein-induced acute pancreatitis.
    World journal of gastroenterology, 2009, Nov-07, Volume: 15, Issue:41

    Topics: Acute Disease; Amylases; Animals; Caffeic Acids; Ceruletide; Cytotoxins; Disease Models, Animal; Edema; Leukocyte Count; Lipase; Male; Pancreas; Pancreatitis; Phenylethyl Alcohol; Rats; Rats, Wistar; Treatment Outcome; Tumor Necrosis Factor-alpha

2009
Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells.
    BMC complementary and alternative medicine, 2009, Nov-17, Volume: 9

    Topics: Angiogenesis Inhibitors; Animals; Apitherapy; Bees; Caffeic Acids; Cell Line; Cell Movement; Cell Proliferation; Endothelial Cells; Fatty Acids; Fibroblasts; Humans; Phenylethyl Alcohol; Pollen; Propolis; Umbilical Veins; Vascular Endothelial Growth Factor A

2009
Protective effect of caffeic acid phenethyl ester on cyclosporine A-induced nephrotoxicity in rats.
    Renal failure, 2009, Volume: 31, Issue:9

    Topics: Animals; Antioxidants; Caffeic Acids; Cyclosporine; Disease Models, Animal; Female; Immunosuppressive Agents; Kidney; Kidney Diseases; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2009
Anticlastogenic effect of caffeic acid phenethyl ester on cisplatin-induced chromosome aberrations in rat bone marrow cells.
    Toxicology and industrial health, 2010, Volume: 26, Issue:1

    Topics: Animals; Antimutagenic Agents; Antineoplastic Agents; Antioxidants; Bone Marrow Cells; Caffeic Acids; Chromosome Aberrations; Cisplatin; Dose-Response Relationship, Drug; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley

2010
Caffeic acid phenethyl ester inhibits arterial smooth muscle cell proliferation and migration in vitro and in vivo using a local delivery system.
    Cellular and molecular biology (Noisy-le-Grand, France), 2009, Nov-15, Volume: 55 Suppl

    Topics: Animals; Blotting, Western; Caffeic Acids; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Vessels; Drug Delivery Systems; Flow Cytometry; Humans; Male; Models, Animal; Muscle, Smooth, Vascular; Phenylethyl Alcohol; Rabbits; Structure-Activity Relationship; Tunica Intima

2009
Optimized enzymatic synthesis of caffeic acid phenethyl ester by RSM.
    New biotechnology, 2010, Feb-28, Volume: 27, Issue:1

    Topics: Animals; Biocatalysis; Caffeic Acids; Enzymes, Immobilized; Fungal Proteins; Humans; Lipase; Phenylethyl Alcohol

2010
Caffeic acid phenethyl ester inhibits nuclear factor-kappaB and protein kinase B signalling pathways and induces caspase-3 expression in primary human CD4+ T cells.
    Clinical and experimental immunology, 2010, Volume: 160, Issue:2

    Topics: Antigens, Dermatophagoides; Asthma; Caffeic Acids; Caspase 3; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Humans; Lymphocyte Activation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Phosphorylation; Propolis; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Receptors, CCR4; Receptors, CXCR3; Signal Transduction; T-Lymphocyte Subsets

2010
Effect of caffeic acid phenethyl ester on the hemostatic alterations associated with toxic-induced acute liver failure.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2010, Volume: 21, Issue:2

    Topics: Animals; Blood Coagulation Tests; Body Weight; Caffeic Acids; Catalase; Glutathione; Hemostasis; Liver Failure, Acute; Liver Function Tests; Male; Oxidative Stress; Phenylethyl Alcohol; Platelet Count; Rats; Rats, Wistar; Superoxide Dismutase

2010
Constitutive and tumor necrosis factor-alpha-stimulated activation of nuclear factor-kappaB in immortalized endometriotic cells and their suppression by trichostatin A.
    Gynecologic and obstetric investigation, 2010, Volume: 70, Issue:1

    Topics: Caffeic Acids; Cell Division; Cell Line, Transformed; Endometriosis; Endometrium; Female; Histone Deacetylase Inhibitors; Humans; Hydrogen Peroxide; Hydroxamic Acids; I-kappa B Kinase; MAP Kinase Kinase Kinases; Oxidants; Phenylethyl Alcohol; Phosphorylation; Stromal Cells; TNF Receptor-Associated Factor 2; TNF Receptor-Associated Factor 6; Transcription Factor RelA

2010
Ameliorative effect of caffeic acid phenethyl ester on histopathological and biochemical changes induced by cigarette smoke in rat kidney.
    Toxicology and industrial health, 2010, Volume: 26, Issue:3

    Topics: Animals; Antioxidants; Blood Chemical Analysis; Caffeic Acids; Dose-Response Relationship, Drug; Inhalation Exposure; Kidney; Kidney Diseases; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Tobacco Smoke Pollution

2010
Caffeic acid phenethyl ester triggers apoptosis through induction of loss of mitochondrial membrane potential in CCRF-CEM cells.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Death; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Membrane Potential, Mitochondrial; Phenylethyl Alcohol; Precursor Cell Lymphoblastic Leukemia-Lymphoma

2011
Structure-activity relationships in the cytoprotective effect of caffeic acid phenethyl ester (CAPE) and fluorinated derivatives: effects on heme oxygenase-1 induction and antioxidant activities.
    European journal of pharmacology, 2010, Jun-10, Volume: 635, Issue:1-3

    Topics: Antioxidants; Caffeic Acids; Cell Line; Cytoprotection; Enzyme Induction; Gene Expression Regulation; Halogenation; Heme Oxygenase-1; Humans; Intracellular Space; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species; RNA, Messenger; Structure-Activity Relationship; Transcription, Genetic; Vitamin K 3

2010
Protective effects of caffeic acid phenethyl ester on iron-induced liver damage in rats.
    Journal of physiology and biochemistry, 2009, Volume: 65, Issue:4

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Caffeic Acids; Catalase; Dextrans; Female; Glutathione Peroxidase; Iron; Lipid Peroxidation; Liver; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Superoxide Dismutase

2009
Caffeic acid phenethyl ester suppresses the induction of eotaxin in human lung fibroblast cells.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2010, Volume: 47, Issue:3

    Topics: Caffeic Acids; Cells, Cultured; Chemokine CCL11; Dose-Response Relationship, Drug; Fibroblasts; Humans; Interleukin-13; Lung; NF-kappa B; Phenylethyl Alcohol; Tumor Necrosis Factor-alpha

2010
Inhibitory effect of caffeic acid phenethyl ester on mice bearing tumor involving angiostatic and apoptotic activities.
    Chemico-biological interactions, 2010, Jul-30, Volume: 186, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caffeic Acids; Carcinoma, Ehrlich Tumor; DNA Fragmentation; Endostatins; Female; Humans; Matrix Metalloproteinase 9; Mice; Neovascularization, Pathologic; Phenylethyl Alcohol

2010
Inhibitory effect of caffeic acid phenethyl ester, a plant-derived polyphenolic compound, on rat intestinal contractility.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: Animals; Caffeic Acids; Flavonoids; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Phenols; Phenylethyl Alcohol; Plants; Polyphenols; Potassium Chloride; Rats; Rats, Wistar

2010
Enzymatic synthesis of caffeic acid phenethyl ester analogues in ionic liquid.
    Journal of biotechnology, 2010, Jul-20, Volume: 148, Issue:2-3

    Topics: Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Equipment Reuse; Esterification; Fungal Proteins; Humans; Imidazoles; Ionic Liquids; Lipase; Methanol; Phenylethyl Alcohol; Pressure; Sulfonamides

2010
Beneficial effect of caffeic acid phenethyl ester (CAPE) on hepatocyte damage induced by bile duct ligation: an electron microscopic examination.
    Ultrastructural pathology, 2010, Volume: 34, Issue:5

    Topics: Animals; Antioxidants; Bile Ducts; Caffeic Acids; Cholestasis; Hepatocytes; Ligation; Liver; Liver Diseases; Male; Microscopy, Electron, Transmission; Phenylethyl Alcohol; Rats

2010
Chitinase induce the release of IL-8 in human airway epithelial cells, via Ca2+-dependent PKC and ERK pathways.
    Scandinavian journal of immunology, 2010, Volume: 72, Issue:1

    Topics: Blotting, Western; Butadienes; Caffeic Acids; Carbazoles; Cell Line, Tumor; Chitinases; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Indoles; Interleukin-8; Naphthalenes; NF-kappa B; Nitriles; Phenylethyl Alcohol; Protein Kinase C; Protein Kinase Inhibitors; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2010
Synthesis of a series of caffeic acid phenethyl amide (CAPA) fluorinated derivatives: comparison of cytoprotective effects to caffeic acid phenethyl ester (CAPE).
    Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14

    Topics: Caffeic Acids; Cell Line; Cytoprotection; Halogenation; Humans; Hydrogen Peroxide; Oxidative Stress; Phenethylamines; Phenylethyl Alcohol; Umbilical Veins

2010
Caffeic acid phenethyl ester-mediated Nrf2 activation and IkappaB kinase inhibition are involved in NFkappaB inhibitory effect: structural analysis for NFkappaB inhibition.
    European journal of pharmacology, 2010, Sep-15, Volume: 643, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Cell Culture Techniques; Cell Line, Tumor; Cell Nucleus; Cytosol; Genes, Reporter; Humans; I-kappa B Kinase; Immunoblotting; Lipopolysaccharides; Luciferases; Macrophages; Mice; Molecular Structure; NF-E2-Related Factor 2; NF-kappa B; Phenylethyl Alcohol; Plasmids; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Transfection; Tumor Necrosis Factor-alpha

2010
Biochemical mechanism of caffeic acid phenylethyl ester (CAPE) selective toxicity towards melanoma cell lines.
    Chemico-biological interactions, 2010, Oct-06, Volume: 188, Issue:1

    Topics: Animals; Apoptosis; Ascorbic Acid; Caffeic Acids; Cell Line, Tumor; Glutathione; Male; Melanoma, Experimental; Monophenol Monooxygenase; NAD; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet

2010
Effects of caffeic acid phenethyl ester on isoproterenol-induced myocardial infarction in rats.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2010, Volume: 10, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Aspartate Aminotransferases; Caffeic Acids; Cardiotonic Agents; Creatine Kinase; Cytotoxins; Female; Flavonoids; Humans; Isoproterenol; L-Lactate Dehydrogenase; Myocardial Infarction; Peroxidase; Phenylethyl Alcohol; Randomized Controlled Trials as Topic; Rats; Rats, Wistar; Superoxide Dismutase

2010
Effects of caffeic acid phenethyl ester on thioacetamide-induced hepatic encephalopathy in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Dec-01, Volume: 34, Issue:8

    Topics: Animals; Antioxidants; Brain; Caffeic Acids; Hepatic Encephalopathy; Male; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Wistar; Thioacetamide

2010
Optimization of ultrasound-accelerated synthesis of enzymatic caffeic acid phenethyl ester by response surface methodology.
    Ultrasonics sonochemistry, 2011, Volume: 18, Issue:1

    Topics: Biocatalysis; Caffeic Acids; Candida; Enzymes, Immobilized; Fungal Proteins; Lipase; Phenylethyl Alcohol; Surface Properties; Ultrasonics

2011
Caffeic acid phenethyl ester inhibits differentiation to adipocytes in 3T3-L1 mouse fibroblasts.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:9

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Caffeic Acids; Cell Differentiation; Dose-Response Relationship, Drug; Growth Inhibitors; Mice; Phenylethyl Alcohol

2010
Antitumor progression potential of caffeic acid phenethyl ester involving p75(NTR) in C6 glioma cells.
    Chemico-biological interactions, 2010, Dec-05, Volume: 188, Issue:3

    Topics: Animals; Antibodies; Antineoplastic Agents; Biomarkers; Caffeic Acids; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioma; I-kappa B Kinase; Lung; Matrix Metalloproteinases; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Nerve Growth Factor; Neuroglia; Phenylethyl Alcohol; Phosphorylation; Rats; Receptor, Nerve Growth Factor; rhoB GTP-Binding Protein

2010
Protective effects of caffeic acid phenethyl ester on retinal ischemia/reperfusion injury in rats.
    Current eye research, 2010, Volume: 35, Issue:10

    Topics: Animals; Apoptosis; Caffeic Acids; Catalase; Electroretinography; Female; Glutathione Peroxidase; In Situ Nick-End Labeling; In Vitro Techniques; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Retina; Retinal Vessels; Superoxide Dismutase

2010
The effects of caffeic acid phenethyl ester and melatonin on age-related vascular remodeling and cardiac damage.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:5

    Topics: Aging; Animals; Antioxidants; Aorta; Caffeic Acids; Catalase; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Assays; Glutathione; Heart; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Mitochondria; Myocardium; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2011
Antiangiogenic properties of an unusual benzo[k,l]xanthene lignan derived from CAPE (caffeic acid phenethyl ester).
    Investigational new drugs, 2012, Volume: 30, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Biomimetics; Caffeic Acids; Cell Line; Dose-Response Relationship, Drug; Endothelial Cells; Female; Granulosa Cells; Neovascularization, Physiologic; Phenylethyl Alcohol; Swine; Time Factors; Vascular Endothelial Growth Factor A

2012
Cytotoxicity of arsenic trioxide is enhanced by (-)-epigallocatechin-3-gallate via suppression of ferritin in cancer cells.
    Toxicology and applied pharmacology, 2011, Jan-01, Volume: 250, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caffeic Acids; Catechin; Cell Line, Tumor; Cytotoxins; Drug Synergism; Ferritins; Heme Oxygenase (Decyclizing); HL-60 Cells; Humans; Neoplasms; Oxides; Phenylethyl Alcohol

2011
Effects of caffeic acid phenethyl ester (CAPE) on hepatopulmonary syndrome.
    Inflammation, 2011, Volume: 34, Issue:6

    Topics: Animals; Caffeic Acids; Hepatopulmonary Syndrome; Inflammation; Liver; Lung; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome

2011
Caffeic acid phenethyl ester protects against oxidative stress-related renal dysfunction in rats treated with cyclosporin A.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:5

    Topics: Acute Kidney Injury; Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Caffeic Acids; Creatinine; Cyclosporine; Disease Models, Animal; Drug Evaluation, Preclinical; Feeding Behavior; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase

2011
Inhibition of AMPK-associated autophagy enhances caffeic acid phenethyl ester-induced cell death in C6 glioma cells.
    Planta medica, 2011, Volume: 77, Issue:9

    Topics: Adenine; AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Caffeic Acids; Cell Death; Cell Line, Tumor; Down-Regulation; Drug Synergism; Glioma; Humans; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Oxidative Stress; Phenylethyl Alcohol; Phosphorylation; Pyrazoles; Pyrimidines; Rats; RNA, Small Interfering

2011
Caffeic acid phenethyl ester inhibits PDGF-induced proliferation of vascular smooth muscle cells via activation of p38 MAPK, HIF-1α, and heme oxygenase-1.
    Journal of natural products, 2011, Mar-25, Volume: 74, Issue:3

    Topics: Animals; Caffeic Acids; Dose-Response Relationship, Drug; Heme Oxygenase-1; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Platelet-Derived Growth Factor; Propolis; Rats; Rats, Sprague-Dawley; Stereoisomerism

2011
Protective effects of CAPE on liver injury induced by CCL₄: an electron microscopy study.
    Ultrastructural pathology, 2011, Volume: 35, Issue:1

    Topics: Animals; Caffeic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Male; Microscopy, Electron, Transmission; Phenylethyl Alcohol; Rats; Rats, Wistar

2011
Role of decoy molecules in neuronal ischemic preconditioning.
    Life sciences, 2011, Apr-11, Volume: 88, Issue:15-16

    Topics: Animals; Animals, Newborn; Apoptosis; Caffeic Acids; Cerebral Cortex; Gene Expression Regulation; Ischemic Preconditioning; Neurons; NF-kappa B; Phenylethyl Alcohol; Rats; Receptors, Death Domain; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor Decoy Receptors

2011
Caffeic acid phenethyl ester reduces spinal cord injury-evoked locomotor dysfunction.
    Biomedical research (Tokyo, Japan), 2011, Volume: 32, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cyclooxygenase 2; Down-Regulation; Female; Interleukin-1beta; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Rats; Rats, Wistar; Spinal Cord Injuries; Spinal Cord Regeneration; Thoracic Vertebrae; Transcription, Genetic

2011
Effect of propolis and caffeic acid phenethyl ester (CAPE) on NFκB activation by HTLV-1 Tax.
    Antiviral research, 2011, Volume: 90, Issue:3

    Topics: Anti-Retroviral Agents; Caffeic Acids; Cell Line; Gene Products, tax; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; NF-kappa B; Phenylethyl Alcohol; Propolis; Transcriptional Activation

2011
The metabolic bioactivation of caffeic acid phenethyl ester (CAPE) mediated by tyrosinase selectively inhibits glutathione S-transferase.
    Chemico-biological interactions, 2011, Jul-15, Volume: 192, Issue:3

    Topics: Caffeic Acids; Cell Line, Tumor; Enzyme Inhibitors; Glutathione Transferase; Humans; Melanoma; Monophenol Monooxygenase; Phenylethyl Alcohol

2011
Caffeic acid phenethyl ester suppresses the production of adipocytokines, leptin, tumor necrosis factor -alpha and resistin, during differentiation to adipocytes in 3T3-L1 cells.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:4

    Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Animals; Caffeic Acids; Cell Differentiation; Glycerolphosphate Dehydrogenase; Insulin Receptor Substrate Proteins; Leptin; Mice; Phenylethyl Alcohol; Propolis; Resistin; Resveratrol; Stilbenes; Triglycerides; Tumor Necrosis Factor-alpha

2011
TNFα-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3K-NF-κB inhibitor, not mTOR inhibitor.
    Rheumatology international, 2012, Volume: 32, Issue:7

    Topics: Aged; Apoptosis; Butadienes; Caffeic Acids; Caspase 3; Cells, Cultured; Chondrocytes; Chromones; Female; Humans; Middle Aged; Morpholines; NF-kappa B; Nitriles; Osteoarthritis; Phenylethyl Alcohol; Phosphoinositide-3 Kinase Inhibitors; Poly(ADP-ribose) Polymerases; Sirolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha

2012
Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders.
    Advances in experimental medicine and biology, 2010, Volume: 698

    Topics: Aging; Antioxidants; Brain; Caffeic Acids; Catechin; Curcumin; Diet; Flavonoids; Neurodegenerative Diseases; Neuroprotective Agents; Phenols; Phenylethyl Alcohol; Polyphenols

2010
Caffeic Acid Phenethyl Ester (CAPE) derived from propolis, a honeybee product, inhibits growth of breast cancer stem cells.
    Investigational new drugs, 2012, Volume: 30, Issue:4

    Topics: Agar; Animals; Apoptosis; Bees; Breast Neoplasms; Caffeic Acids; Cell Cycle; Cell Differentiation; Cell Proliferation; Cell Separation; Drug Screening Assays, Antitumor; Female; Honey; Humans; Mice; Neoplastic Stem Cells; Phenotype; Phenylethyl Alcohol; Propolis; Spheroids, Cellular; Tumor Cells, Cultured

2012
Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:1

    Topics: Antineoplastic Agents; Biological Availability; Caffeic Acids; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chromones; Curcuma; Curcumin; Drug Therapy, Combination; Enzyme Inhibitors; ErbB Receptors; Humans; Morpholines; NF-kappa B; Phenylethyl Alcohol; Phosphoinositide-3 Kinase Inhibitors; Phytotherapy; Plant Extracts; Pyrimidines; Quinazolines; Receptors, Fibroblast Growth Factor; Signal Transduction; Somatomedins; Tyrphostins

2012
Caffeic acid phenethyl ester (CAPE), derived from a honeybee product propolis, exhibits a diversity of anti-tumor effects in pre-clinical models of human breast cancer.
    Cancer letters, 2011, Sep-01, Volume: 308, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bees; Breast Neoplasms; Caffeic Acids; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Female; Humans; Mice; Mice, SCID; Neovascularization, Pathologic; NF-kappa B; Phenylethyl Alcohol; Propolis; Xenograft Model Antitumor Assays

2011
Caffeic acid phenethyl ester prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration.
    Neuroscience, 2011, Aug-11, Volume: 188

    Topics: Animals; Blotting, Western; Brain; Caffeic Acids; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Degeneration; Neuroprotective Agents; Phenylethyl Alcohol

2011
Caffeic acid phenethyl ester suppresses eotaxin secretion and nuclear p-STAT6 in human lung fibroblast cells.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2011, Volume: 44, Issue:6

    Topics: Caffeic Acids; Cell Line; Cell Nucleus; Cell Survival; Chemokine CCL11; DNA; Fibroblasts; Humans; Interleukin-4; Phenylethyl Alcohol; Phosphorylation; STAT6 Transcription Factor; Statistics, Nonparametric; Tumor Necrosis Factor-alpha

2011
Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties.
    International journal of food sciences and nutrition, 2011, Volume: 62, Issue:8

    Topics: Antioxidants; Caffeic Acids; Emulsions; Linoleic Acid; Lipid Peroxidation; Phenylethyl Alcohol; Plant Extracts; Polyphenols; Propolis

2011
Protective effects of caffeic acid phenethyl ester (CAPE) on intestinal damage in necrotizing enterocolitis.
    Pediatric surgery international, 2011, Volume: 27, Issue:11

    Topics: Administration, Oral; Animals; Animals, Newborn; Apoptosis; Caffeic Acids; Caspase 9; Cell Count; Disease Models, Animal; Enterocolitis, Necrotizing; Ileum; Immunohistochemistry; In Situ Nick-End Labeling; NF-kappa B; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome; Xanthine Oxidase

2011
Nuclear factor-kappa β regulates Notch signaling in production of proinflammatory cytokines and nitric oxide in murine BV-2 microglial cells.
    Neuroscience, 2011, Sep-29, Volume: 192

    Topics: Animals; Blotting, Western; Caffeic Acids; Cell Line; Cell Separation; Cytokines; Cytotoxins; Flow Cytometry; Fluorescent Antibody Technique; Inflammation; Mice; Microglia; NF-kappa B; Nitric Oxide; Phenylethyl Alcohol; Real-Time Polymerase Chain Reaction; Receptors, Notch; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

2011
The efficiency of CAPE on retardation of hepatic fibrosis in biliary obstructed rats.
    Journal of molecular histology, 2011, Volume: 42, Issue:5

    Topics: Animals; Caffeic Acids; Cell Proliferation; Cholestasis; Glutathione Peroxidase; Hydroxyproline; Immunohistochemistry; In Situ Nick-End Labeling; Liver; Liver Cirrhosis; Male; Malondialdehyde; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2011
Caffeic acid phenethyl ester modulates gentamicin-induced oxidative nephrotoxicity in kidney of rats.
    Biological trace element research, 2012, Volume: 145, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Caffeic Acids; Creatinine; Female; Gentamicins; Kidney; Kidney Diseases; Lipid Peroxidation; Nitric Oxide; Oxidoreductases; Phenylethyl Alcohol; Rats; Rats, Wistar

2012
Effect of ionic liquids on enzymatic synthesis of caffeic acid phenethyl ester.
    Bioprocess and biosystems engineering, 2012, Volume: 35, Issue:1-2

    Topics: Caffeic Acids; Enzyme Activation; Ionic Liquids; Lipase; Phenylethyl Alcohol

2012
Role of interleukin 1 beta in esophageal squamous cell carcinoma.
    Journal of molecular medicine (Berlin, Germany), 2012, Volume: 90, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Disease Progression; Drug Resistance, Neoplasm; Esophageal Neoplasms; Humans; Interleukin-1beta; Male; Mice; Mice, Nude; Middle Aged; NF-kappa B; Phenylethyl Alcohol; Prognosis; Radiation Tolerance; Survival Analysis

2012
Stability of caffeic acid phenethyl amide (CAPA) in rat plasma.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:5

    Topics: Amides; Animals; Caffeic Acids; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; Kinetics; Male; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Temperature

2012
Caffeic acid phenethyl ester inhibits proliferation and migration, and induces apoptosis in platelet-derived growth factor-BB-stimulated human coronary smooth muscle cells.
    Journal of vascular research, 2012, Volume: 49, Issue:1

    Topics: Apoptosis; Becaplermin; Caffeic Acids; Caspases; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Vessels; Cytochromes c; Humans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-sis

2012
Protective role of caffeic acid on lambda cyhalothrin-induced changes in sperm characteristics and testicular oxidative damage in rats.
    Toxicology and industrial health, 2012, Volume: 28, Issue:7

    Topics: Analysis of Variance; Animals; Antioxidants; Body Weight; Caffeic Acids; Cell Survival; Glutathione; Lipid Peroxidation; Male; Nitriles; Oxidative Stress; Phenylethyl Alcohol; Pyrethrins; Rats; Rats, Wistar; Sperm Count; Sperm Motility; Spermatozoa; Testis

2012
Catechols in caffeic acid phenethyl ester are essential for inhibition of TNF-mediated IP-10 expression through NF-κB-dependent but HO-1- and p38-independent mechanisms in mouse intestinal epithelial cells.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:12

    Topics: Animals; Caffeic Acids; Catechols; Cell Line; Chemokine CXCL10; Epithelial Cells; Heme Oxygenase-1; I-kappa B Proteins; Intestinal Mucosa; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Phosphorylation; Signal Transduction; Transcription Factors; Tumor Necrosis Factor-alpha

2011
Caffeic acid phenethyl ester (CAPE) prevents methotrexate-induced hepatorenal oxidative injury in rats.
    The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:12

    Topics: Animals; Antimetabolites, Antineoplastic; Caffeic Acids; Chemical and Drug Induced Liver Injury; Female; Glutathione; Interleukin-1beta; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tumor Necrosis Factor-alpha

2011
Neuroprotective effects of caffeic acid phenethyl ester on experimental traumatic brain injury in rats.
    Journal of molecular histology, 2012, Volume: 43, Issue:1

    Topics: Animals; Brain; Brain Injuries; Caffeic Acids; Caspase 3; Catalase; Glutathione Peroxidase; Male; Malondialdehyde; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2012
Caffeic Acid phenethyl ester protects blood-brain barrier integrity and reduces contusion volume in rodent models of traumatic brain injury.
    Journal of neurotrauma, 2012, Apr-10, Volume: 29, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain Injuries; Caffeic Acids; Disease Models, Animal; Fluorescent Antibody Technique; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Recovery of Function

2012
Caffeic Acid phenethyl ester possessing various immunomodulatory effects is a potentially effective therapy for asthma.
    Pediatrics and neonatology, 2011, Volume: 52, Issue:6

    Topics: Asthma; Caffeic Acids; Cytokines; Female; Humans; Male; Phenylethyl Alcohol; Th1 Cells; Th2 Cells

2011
The immunoregulatory effects of caffeic acid phenethyl ester on the cytokine secretion of peripheral blood mononuclear cells from asthmatic children.
    Pediatrics and neonatology, 2011, Volume: 52, Issue:6

    Topics: Asthma; Caffeic Acids; Child; Child, Preschool; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Leukocytes, Mononuclear; Male; Phenylethyl Alcohol; T-Lymphocytes, Regulatory; Th1 Cells; Th2 Cells

2011
Caffeic acid phenethyl ester extends survival of a mouse model of amyotrophic lateral sclerosis.
    Neuroscience, 2012, Mar-15, Volume: 205

    Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Transgenic; Neuroprotective Agents; Phenylethyl Alcohol; Survival Rate; Treatment Outcome

2012
Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving haem oxygenase-1 and brain-derived neurotrophic factor.
    British journal of pharmacology, 2012, Volume: 166, Issue:3

    Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Caffeic Acids; Disease Models, Animal; Dopaminergic Neurons; Enzyme Induction; Heme Oxygenase-1; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitric Oxide; Parkinsonian Disorders; Phenylethyl Alcohol; Rats; Rats, Wistar; Substantia Nigra

2012
Cancer prevention mediated by caffeic acid phenethyl ester involves cyp2b1/2 modulation in hepatocarcinogenesis.
    Toxicologic pathology, 2012, Volume: 40, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Caffeic Acids; Carcinogenicity Tests; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochromes; Diethylnitrosamine; Disease Models, Animal; Liver Neoplasms, Experimental; Male; Phenylethyl Alcohol; Proadifen; Rats; Rats, Inbred F344; Steroid Hydroxylases

2012
Caffeic acid phenethyl ester causes p21 induction, Akt signaling reduction, and growth inhibition in PC-3 human prostate cancer cells.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Synergism; Humans; Male; Microarray Analysis; p21-Activated Kinases; Phenylethyl Alcohol; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction

2012
Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Amides; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Caffeic Acids; Humans; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Neutrophils; Phenylethyl Alcohol; Structure-Activity Relationship

2012
Effect of caffeic acid phenethyl ester (CAPE) on H₂O₂ induced oxidative and inflammatory responses in human middle ear epithelial cells.
    International journal of pediatric otorhinolaryngology, 2012, Volume: 76, Issue:5

    Topics: Antioxidants; Blotting, Western; Caffeic Acids; Cell Culture Techniques; Cytokines; Ear, Middle; Epithelial Cells; Flow Cytometry; Humans; Hydrogen Peroxide; Inflammation; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction

2012
Role of caffeic acid phenethyl ester on mitomycin C induced clastogenesis: analysis of chromosome aberrations, micronucleus, mitotic index and adenosine deaminase activity in vivo.
    Journal of applied genetics, 2012, Volume: 53, Issue:2

    Topics: Adenosine Deaminase; Administration, Oral; Animals; Bone Marrow Cells; Caffeic Acids; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mitotic Index; Mutagenesis; Phenylethyl Alcohol; Reactive Oxygen Species; Spleen; Thymus Gland

2012
Protective effect of caffeic acid phenethyl ester against cadmium-induced renal damage in mice.
    The Journal of toxicological sciences, 2012, Volume: 37, Issue:2

    Topics: Animals; Antioxidants; Cadmium; Caffeic Acids; Carcinogens; Catalase; Environmental Pollutants; Glutathione; Kidney; Male; Mice; Oxidative Stress; Phenylethyl Alcohol; Superoxide Dismutase; Zinc

2012
Vimentin and PSF act in concert to regulate IbeA+ E. coli K1 induced activation and nuclear translocation of NF-κB in human brain endothelial cells.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Active Transport, Cell Nucleus; Blood-Brain Barrier; Brain; Caffeic Acids; Cell Movement; Cells, Cultured; Endothelial Cells; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Gene Knockdown Techniques; Host-Pathogen Interactions; Humans; Membrane Proteins; Meningitis, Bacterial; Microvessels; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neutrophil Infiltration; Neutrophils; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Protein Binding; Protein Interaction Domains and Motifs; PTB-Associated Splicing Factor; RNA-Binding Proteins; Sequence Deletion; Signal Transduction; Tubulin; Vimentin

2012
Melatonin and CAPE are able to prevent the liver from oxidative damage in rats: an ultrastructural and biochemical study.
    Ultrastructural pathology, 2012, Volume: 36, Issue:3

    Topics: Age Factors; Animals; Antioxidants; Caffeic Acids; Catalase; Glutathione; Glutathione Peroxidase; Liver; Liver Diseases; Male; Malondialdehyde; Melatonin; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2012
Caffeic acid phenethyl ester suppresses the proliferation of human prostate cancer cells through inhibition of p70S6K and Akt signaling networks.
    Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:5

    Topics: Animals; Caffeic Acids; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Down-Regulation; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oncogene Protein v-akt; Phenylethyl Alcohol; Prostatic Neoplasms; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Xenograft Model Antitumor Assays

2012
Caffeic acid phenethyl ester reduces the activation of the nuclear factor κB pathway by high-fat diet-induced obesity in mice.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:11

    Topics: Animals; Blood Glucose; Caffeic Acids; Dietary Fats; Enzyme-Linked Immunosorbent Assay; Glucose Tolerance Test; Inflammation; Insulin; Male; Mice; NF-kappa B; Obesity; Phenylethyl Alcohol; Signal Transduction

2012
Simultaneous determination of caffeic acid phenethyl ester and its metabolite caffeic acid in dog plasma using liquid chromatography tandem mass spectrometry.
    Talanta, 2012, May-30, Volume: 94

    Topics: Animals; Caffeic Acids; Chemical Precipitation; Chromatography, Liquid; Dogs; Drug Stability; Phenylethyl Alcohol; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2012
Caffeic acid phenethyl ester attenuates IgE-induced immediate allergic reaction.
    Inflammopharmacology, 2013, Volume: 21, Issue:2

    Topics: Adenosine; Animals; Anti-Allergic Agents; Caffeic Acids; Capillary Permeability; Guinea Pigs; Histamine; Histamine Release; Hypersensitivity; Immunoglobulin E; Leukotrienes; Male; Mast Cells; Passive Cutaneous Anaphylaxis; Phenylethyl Alcohol; Rats; Rats, Wistar; Serotonin; Vasoconstriction

2013
Caffeic acid phenethyl ester prevents detrimental effects of remote ischemia-reperfusion injury on healing of colonic anastomoses.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2013, Volume: 26, Issue:1

    Topics: Anastomosis, Surgical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Colon; Cytokines; Drug Evaluation, Preclinical; Hydroxyproline; Laparotomy; Male; Malondialdehyde; Mesenteric Artery, Superior; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Surgical Wound Dehiscence; Wound Healing; Xanthine Oxidase

2013
Caffeic acid phenethyl ester effects in the kidney during ischemia and reperfusion in rats anesthetized with isoflurane.
    Transplantation proceedings, 2012, Volume: 44, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Biomarkers; Caffeic Acids; Creatinine; Disease Models, Animal; Isoflurane; Kidney; Male; Necrosis; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Time Factors

2012
Caffeic acid phenethyl ester protects 661W cells from H2O2-mediated cell death and enhances electroretinography response in dim-reared albino rats.
    Molecular vision, 2012, Volume: 18

    Topics: Albinism; Animals; Caffeic Acids; Cell Death; Electroretinography; Eye Proteins; Fatty Acids, Omega-3; Gene Expression; Heme Oxygenase-1; Hydrogen Peroxide; Intercellular Adhesion Molecule-1; L-Lactate Dehydrogenase; Light; Lipoxygenases; NF-kappa B; Phenylethyl Alcohol; Photoreceptor Cells, Vertebrate; Propolis; Protective Agents; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger

2012
Impairment of antioxidant defenses as a contributor to arsenite-induced cell transformation.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2012, Volume: 25, Issue:5

    Topics: Antioxidants; Arsenites; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dicumarol; Environmental Pollutants; Ferritins; Gene Expression; Genes, p53; Humans; Intracellular Signaling Peptides and Proteins; Models, Biological; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Phenylethyl Alcohol; Proto-Oncogene Proteins; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Suppressor Protein p53

2012
Early treatment of radiation-induced heart damage in rats by caffeic acid phenethyl ester.
    European journal of pharmacology, 2012, Oct-05, Volume: 692, Issue:1-3

    Topics: Animals; Biomarkers; Caffeic Acids; Heart; Heart Injuries; Male; Oxidative Stress; Phenylethyl Alcohol; Radiation Injuries; Rats; Rats, Sprague-Dawley; Time Factors

2012
Impact of lysophosphatidylcholine on the plasminogen activator system in cultured vascular smooth muscle cells.
    Journal of Korean medical science, 2012, Volume: 27, Issue:7

    Topics: Animals; Benz(a)Anthracenes; Caffeic Acids; Cells, Cultured; Genistein; Lipoproteins, LDL; Lysophosphatidylcholines; Muscle, Smooth, Vascular; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Plasminogen Activator Inhibitor 1; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tissue Plasminogen Activator; Transcription, Genetic; Up-Regulation; Vitamin E

2012
Not only melatonin but also caffeic acid phenethyl ester protects kidneys against aging-related oxidative damage in Sprague Dawley rats.
    Ultrastructural pathology, 2012, Volume: 36, Issue:4

    Topics: Aging; Animals; Antioxidants; Caffeic Acids; Cytoprotection; Kidney; Male; Melatonin; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2012
CAPE suppresses VEGFR-2 activation, and tumor neovascularization and growth.
    Journal of molecular medicine (Berlin, Germany), 2013, Volume: 91, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms; Neovascularization, Pathologic; Phenylethyl Alcohol; Tumor Burden; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2013
Caffeic acid phenethyl ester protects kidneys against acetylsalicylic acid toxicity in rats.
    Renal failure, 2012, Volume: 34, Issue:9

    Topics: Acute Kidney Injury; Animals; Aspirin; Caffeic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Kidney; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2012
Caffeic acid phenethyl ester ameliorates cadmium-induced kidney mitochondrial injury.
    Chemico-biological interactions, 2012, Oct-25, Volume: 200, Issue:1

    Topics: Acute Kidney Injury; Animals; Cadmium; Caffeic Acids; Environmental Pollutants; Male; Mitochondria; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2012
Comparative analysis of the protective effects of caffeic acid phenethyl ester (CAPE) on pulmonary contusion lung oxidative stress and serum copper and zinc levels in experimental rat model.
    Biological trace element research, 2013, Volume: 151, Issue:1

    Topics: Analysis of Variance; Animals; Blood Gas Analysis; Caffeic Acids; Catalase; Contusions; Copper; Disease Models, Animal; Humans; Lung; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Zinc

2013
Effects of caffeic acid phenethyl ester on anastomotic healing in secondary peritonitis.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2012, Volume: 25, Issue:5

    Topics: Anastomosis, Surgical; Animals; Caffeic Acids; Colon; Disease Models, Animal; Glutathione; Hydroxyproline; Male; Malondialdehyde; Peritonitis; Peroxidase; Phenylethyl Alcohol; Pressure; Rats; Rats, Wistar; Stress, Mechanical; Superoxide Dismutase; Wound Healing

2012
Inhibition of Ca(2+) release-activated Ca(2+) channel (CRAC) by curcumin and caffeic acid phenethyl ester (CAPE) via electrophilic addition to a cysteine residue of Orai1.
    Biochemical and biophysical research communications, 2012, Nov-09, Volume: 428, Issue:1

    Topics: Caffeic Acids; Calcium; Calcium Channels; Curcumin; Cysteine; HEK293 Cells; Humans; Mutation; ORAI1 Protein; Phenylethyl Alcohol

2012
Caffeic acid phenethyl ester suppresses the production of pro-inflammatory cytokines in hypertrophic adipocytes through lipopolysaccharide-stimulated macrophages.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:11

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Line; Cytokines; Gene Expression Regulation; Hypertrophy; Lipopolysaccharides; Macrophages; Mice; Phenylethyl Alcohol; RNA, Messenger

2012
Ethanolic extract of propolis, chrysin, CAPE inhibit human astroglia cells.
    Advances in medical sciences, 2012, Volume: 57, Issue:2

    Topics: Apoptosis; Astrocytes; Caffeic Acids; Cell Line; Cell Survival; Cytotoxins; Ethanol; Flavonoids; Humans; Phenylethyl Alcohol; Propolis

2012
Caffeic acid phenethyl ester alleviates mesenteric ischemia/reperfusion injury.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2012, Volume: 25, Issue:6

    Topics: Animals; Antioxidants; Caffeic Acids; Cytokines; Glutathione Peroxidase; Intestine, Small; Male; Malondialdehyde; Models, Animal; Nitrates; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion Injury; Xanthine Oxidase

2012
Synthesis and antiradical/antioxidant activities of caffeic acid phenethyl ester and its related propionic, acetic, and benzoic acid analogues.
    Molecules (Basel, Switzerland), 2012, Dec-10, Volume: 17, Issue:12

    Topics: Acetic Acid; Antioxidants; Benzoic Acid; Caffeic Acids; Carbon; Lipid Peroxidation; Oxidation-Reduction; Phenylethyl Alcohol; Propionates; Propolis

2012
Induction of apoptosis by a potent caffeic acid derivative, caffeic acid undecyl ester, is mediated by mitochondrial damage in NALM-6 human B cell leukemia cells.
    Oncology reports, 2013, Volume: 29, Issue:2

    Topics: Analysis of Variance; Apoptosis; Caffeic Acids; Caspase 3; Cell Survival; Down-Regulation; Genes, bcl-2; Humans; Inhibitory Concentration 50; Leukemia, B-Cell; Lymphocytes; Membrane Potential, Mitochondrial; Phenylethyl Alcohol; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

2013
Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2.
    British journal of pharmacology, 2013, Volume: 168, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Line; Chromatography, Gas; Disease Models, Animal; Gene Expression Regulation; HEK293 Cells; Humans; Inflammation; Interferon Regulatory Factor-3; Lipopolysaccharides; Lymphocyte Antigen 96; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Signal Transduction; Tandem Mass Spectrometry; Toll-Like Receptor 4

2013
Caffeic acid phenethyl ester protects against the dopaminergic neuronal loss induced by 6-hydroxydopamine in rats.
    Neuroscience, 2013, Mar-13, Volume: 233

    Topics: Adrenergic Agents; Animals; Antioxidants; Caffeic Acids; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Free Radical Scavengers; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Phenylethyl Alcohol; Rats; Rats, Wistar

2013
Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells.
    Neuroscience letters, 2013, Feb-22, Volume: 535

    Topics: Acrolein; ADAM Proteins; ADAM10 Protein; Amyloid Precursor Protein Secretases; Animals; Antioxidants; Aspartic Acid Endopeptidases; Caffeic Acids; Cell Line; Cell Survival; Glutathione; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; MAP Kinase Signaling System; Membrane Proteins; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; Phenylethyl Alcohol; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species

2013
Caffeic acid phenethyl ester induces adrenoleukodystrophy (Abcd2) gene in human X-ALD fibroblasts and inhibits the proinflammatory response in Abcd1/2 silenced mouse primary astrocytes.
    Biochimica et biophysica acta, 2013, Volume: 1831, Issue:4

    Topics: Acetyltransferases; Adrenoleukodystrophy; Animals; Astrocytes; ATP Binding Cassette Transporter, Subfamily D; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Caffeic Acids; Cells, Cultured; Child; Fatty Acid Elongases; Fibroblasts; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol

2013
Antibacterial activity of Sonoran propolis and some of its constituents against clinically significant Vibrio species.
    Foodborne pathogens and disease, 2013, Volume: 10, Issue:2

    Topics: Anti-Bacterial Agents; Caffeic Acids; Flavonoids; Mexico; Microbial Sensitivity Tests; Phenylethyl Alcohol; Propolis; Vibrio; Vibrio cholerae O1

2013
The protective effects of caffeic acid phenethyl ester in isoniazid and ethambutol-induced ocular toxicity of rats.
    Cutaneous and ocular toxicology, 2013, Volume: 32, Issue:3

    Topics: Animals; Caffeic Acids; Ethambutol; Isoniazid; Male; Malondialdehyde; Optic Nerve Diseases; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Sprague-Dawley; Retinal Diseases; Retinal Ganglion Cells; Superoxide Dismutase

2013
Optimization of lipase-catalyzed synthesis of caffeic acid phenethyl ester in ionic liquids by response surface methodology.
    Bioprocess and biosystems engineering, 2013, Volume: 36, Issue:6

    Topics: Caffeic Acids; Enzymes, Immobilized; Fungal Proteins; Hot Temperature; Imidazoles; Lipase; Phenylethyl Alcohol; Sulfonamides

2013
The effect of caffeic acid phenethyl ester analogues in a modified resistant hepatocyte model.
    Anti-cancer drugs, 2013, Volume: 24, Issue:4

    Topics: 2-Acetylaminofluorene; Acetanilides; Animals; Anticarcinogenic Agents; Antioxidants; Caffeic Acids; Carcinogens; Cell Division; Cinnamates; Diethylnitrosamine; Drug Evaluation, Preclinical; Drug Resistance; Glutathione S-Transferase pi; Hepatectomy; Hepatocytes; Ki-67 Antigen; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; Molecular Structure; Phenylethyl Alcohol; Precancerous Conditions; Rats; Rats, Inbred F344; Transcription Factor RelA

2013
Electrophysiological and mechanical effects of caffeic acid phenethyl ester, a novel cardioprotective agent with antiarrhythmic activity, in guinea-pig heart.
    European journal of pharmacology, 2013, Feb-28, Volume: 702, Issue:1-3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeic Acids; Cardiotonic Agents; Electrophysiological Phenomena; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Papillary Muscles; Phenylethyl Alcohol

2013
Caffeic acid phenethyl ester modulates aflatoxin B1-induced hepatotoxicity in rats.
    Cell biochemistry and function, 2013, Volume: 31, Issue:8

    Topics: Aflatoxin B1; Animals; Apoptosis; Caffeic Acids; Cytoprotection; Dose-Response Relationship, Drug; Free Radicals; Hepatocytes; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Structure-Activity Relationship

2013
Caffeic acid phenylethyl ester and MG132, two novel nonconventional chemotherapeutic agents, induce apoptosis of human leukemic cells by disrupting mitochondrial function.
    Targeted oncology, 2014, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Apoptosis; Caffeic Acids; Child; Child, Preschool; Drugs, Investigational; Female; Humans; Leukemia; Leupeptins; Male; Middle Aged; Mitochondria; Phenylethyl Alcohol; Tumor Cells, Cultured; Young Adult

2014
Class 3 inhibition of hERG K+ channel by caffeic acid phenethyl ester (CAPE) and curcumin.
    Pflugers Archiv : European journal of physiology, 2013, Volume: 465, Issue:8

    Topics: Action Potentials; Caffeic Acids; Curcumin; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Kinetics; Phenylethyl Alcohol; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2013
The effects of caffeic acid phenethyl ester in acute methanol toxicity on rat retina and optic nerve.
    Cutaneous and ocular toxicology, 2013, Volume: 32, Issue:4

    Topics: Alcohol Dehydrogenase; Animals; Antidotes; Caffeic Acids; Ethanol; Fomepizole; Humans; Male; Methanol; Molecular Docking Simulation; Optic Nerve; Oxidative Stress; Phenylethyl Alcohol; Pyrazoles; Rats; Rats, Sprague-Dawley; Retina

2013
Caffeic acid phenethyl ester as an adjuvant therapy for advanced prostate cancer.
    Medical hypotheses, 2013, Volume: 80, Issue:5

    Topics: Caffeic Acids; Chemotherapy, Adjuvant; Humans; Male; Phenylethyl Alcohol; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt

2013
Caffeic acid phenethyl ester induces E2F-1-mediated growth inhibition and cell-cycle arrest in human cervical cancer cells.
    The FEBS journal, 2013, Volume: 280, Issue:11

    Topics: Apoptosis; Caffeic Acids; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; E2F1 Transcription Factor; Female; Gene Knockdown Techniques; HeLa Cells; Humans; Phenylethyl Alcohol; Promoter Regions, Genetic; Uterine Cervical Neoplasms

2013
PAK1-deficiency/down-regulation reduces brood size, activates HSP16.2 gene and extends lifespan in Caenorhabditis elegans.
    Drug discoveries & therapeutics, 2013, Volume: 7, Issue:1

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caffeic Acids; Down-Regulation; Green Fluorescent Proteins; Heat-Shock Proteins; Longevity; p21-Activated Kinases; Phenylethyl Alcohol; Phenylpropionates; Protein Kinase Inhibitors; Recombinant Fusion Proteins; Reproduction; Signal Transduction

2013
Increase of TNFα-stimulated osteoarthritic chondrocytes apoptosis and decrease of matrix metalloproteinases 9 by NF-κB inhibition.
    Biomedical and environmental sciences : BES, 2013, Volume: 26, Issue:4

    Topics: Aged; Apoptosis; Caffeic Acids; Calcium; Cells, Cultured; Chondrocytes; Drug Evaluation, Preclinical; Female; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; NF-kappa B; Osteoarthritis; Phenylethyl Alcohol; Tumor Necrosis Factor-alpha

2013
Effect of caffeic acid phenethyl ester on intra-abdominal adhesion in rats.
    Gynecologic and obstetric investigation, 2013, Volume: 75, Issue:4

    Topics: Abdominal Cavity; Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Disease Models, Animal; Female; Infusions, Parenteral; Laparotomy; Phenylethyl Alcohol; Rats; Tissue Adhesions; Uterus

2013
NMR metabolomics analysis of the effects of 5-lipoxygenase inhibitors on metabolism in glioblastomas.
    Journal of proteome research, 2013, May-03, Volume: 12, Issue:5

    Topics: Antineoplastic Agents; Arachidonate 5-Lipoxygenase; Caffeic Acids; Cell Line, Tumor; Drug Screening Assays, Antitumor; Free Radical Scavengers; Glioblastoma; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxyurea; Leukotrienes; Lipid Metabolism; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Metabolome; Metabolomics; Phenylethyl Alcohol; Principal Component Analysis

2013
Separation and purification of the antioxidant compounds, caffeic acid phenethyl ester and caffeic acid from mushrooms by molecularly imprinted polymer.
    Food chemistry, 2013, Aug-15, Volume: 139, Issue:1-4

    Topics: Adsorption; Agaricales; Antioxidants; Caffeic Acids; Molecular Imprinting; Phenylethyl Alcohol; Polymers; Solid Phase Extraction

2013
Suppression of nuclear factor erythroid 2-related factor 2 via extracellular signal-regulated kinase contributes to bleomycin-induced oxidative stress and fibrogenesis.
    Toxicology letters, 2013, Jun-20, Volume: 220, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Caffeic Acids; Cell Survival; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; Gene Silencing; Hydroxyproline; Intubation, Intratracheal; Lipid Peroxidation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Oxidoreductases; Phenylethyl Alcohol; Pulmonary Fibrosis; Reactive Oxygen Species

2013
Ameliorative effects of caffeic acid phenethyl ester on an eccentric exercise-induced skeletal muscle injury by down-regulating NF-κb mediated inflammation.
    Pharmacology, 2013, Volume: 91, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Creatine Kinase; Cyclooxygenase 2; Down-Regulation; Inflammation; Male; Muscle, Skeletal; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Phenylethyl Alcohol; Physical Conditioning, Animal; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar

2013
Protective effects of caffeic acid phenethyl ester on dose-dependent intoxication of rats with paraquat.
    Toxicology and industrial health, 2015, Volume: 31, Issue:11

    Topics: Animals; Antioxidants; Caffeic Acids; Dose-Response Relationship, Drug; Female; Pancreas; Paraquat; Phenylethyl Alcohol; Rats; Rats, Wistar

2015
Effects of caffeic acid phenethyl ester (CAPE) on membrane potential and intracellular calcium in human endothelial cells.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:6

    Topics: Caffeic Acids; Calcium; Cell Proliferation; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Membrane Potentials; Nitrogen Oxides; Phenylethyl Alcohol

2013
Caffeic acid phenethyl ester (CAPE), an active component of propolis, inhibits Helicobacter pylori peptide deformylase activity.
    Biochemical and biophysical research communications, 2013, May-31, Volume: 435, Issue:2

    Topics: Amidohydrolases; Binding Sites; Caffeic Acids; Helicobacter pylori; Phenylethyl Alcohol; Propolis; Protein Binding

2013
Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of Akt signaling.
    International journal of molecular sciences, 2013, Apr-24, Volume: 14, Issue:5

    Topics: Apoptosis; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Fluorouracil; Humans; Models, Biological; Mouth Neoplasms; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Stem Cell Assay

2013
Caffeic acid phenethyl ester suppresses melanoma tumor growth by inhibiting PI3K/AKT/XIAP pathway.
    Carcinogenesis, 2013, Volume: 34, Issue:9

    Topics: Animals; Apoptosis; Caffeic Acids; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Melanoma; Mice; Oncogene Protein v-akt; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Signal Transduction; Skin Neoplasms; X-Linked Inhibitor of Apoptosis Protein

2013
Caffeic acid phenethyl ester inhibits endothelial tissue factor expression.
    Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:6

    Topics: Aorta; Caffeic Acids; Cells, Cultured; Endothelial Cells; Fibrinolytic Agents; Humans; Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; RNA, Messenger; Thromboplastin; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2013
Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line.
    Journal of inorganic biochemistry, 2013, Volume: 128

    Topics: 3' Untranslated Regions; Aluminum; Animals; Caffeic Acids; Cell Line; Down-Regulation; Epigenesis, Genetic; Gene Expression; Membrane Glycoproteins; Mice; Microglia; MicroRNAs; NF-kappa B; Phagocytosis; Phenylethyl Alcohol; Receptors, Immunologic

2013
Protective and anti-angiopathy effects of caffeic acid phenethyl ester against induced type 1 diabetes in vivo.
    International immunopharmacology, 2013, Volume: 17, Issue:2

    Topics: Animals; Blood Glucose; Caffeic Acids; Cells, Cultured; Diabetes Mellitus, Experimental; Endostatins; Humans; Insulin; Interferon-gamma; Interleukin-1beta; Islets of Langerhans; Male; Matrix Metalloproteinase 9; Mice; Neovascularization, Pathologic; Nitric Oxide; Phenylethyl Alcohol; Vesicular Transport Proteins

2013
Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells.
    IUBMB life, 2013, Volume: 65, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Docetaxel; Drug Synergism; Estrogen Receptor alpha; Estrogen Receptor beta; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Inhibitory Concentration 50; Male; Paclitaxel; Phenylethyl Alcohol; Prostatic Neoplasms; Taxoids

2013
CAPE promotes TRAIL-induced apoptosis through the upregulation of TRAIL receptors via activation of p38 and suppression of JNK in SK-Hep1 hepatocellular carcinoma cells.
    International journal of oncology, 2013, Volume: 43, Issue:4

    Topics: Animals; Apoptosis; Bees; Caffeic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Propolis; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation

2013
The protective effects of caffeic acid phenethyl ester against toluene-induced nephrotoxicity in rats.
    Toxicology and industrial health, 2016, Volume: 32, Issue:1

    Topics: Animals; Antioxidants; Blood Urea Nitrogen; Caffeic Acids; Catalase; Creatinine; Dose-Response Relationship, Drug; Glutathione Peroxidase; Kidney; Male; Malondialdehyde; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Toluene

2016
[Impact of NF-kappaB inhibitor on STAT3 translocation in PC-3 prostate cancer cell line].
    Zhonghua nan ke xue = National journal of andrology, 2013, Volume: 19, Issue:6

    Topics: Caffeic Acids; Cell Line, Tumor; Humans; Interleukin-6; Male; NF-kappa B; Phenylethyl Alcohol; Prostatic Neoplasms; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha

2013
Strategies for ascertaining the interference of phase II metabolites co-eluting with parent compounds using LC-MS/MS.
    Journal of separation science, 2013, Volume: 36, Issue:16

    Topics: Caffeic Acids; Chromatography, High Pressure Liquid; Humans; Phenylethyl Alcohol; Reproducibility of Results; Tandem Mass Spectrometry

2013
Design, synthesis and pharmacological evaluation of (E)-3,4-dihydroxy styryl sulfonamides derivatives as multifunctional neuroprotective agents against oxidative and inflammatory injury.
    Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17

    Topics: Animals; Blood-Brain Barrier; Caffeic Acids; Cell Line, Tumor; Drug Design; Free Radical Scavengers; Mice; Microglia; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Stereoisomerism; Sulfonamides

2013
Caffeic acid phenethyl ester activation of Nrf2 pathway is enhanced under oxidative state: structural analysis and potential as a pathologically targeted therapeutic agent in treatment of colonic inflammation.
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Chromatography, High Pressure Liquid; Colitis; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Immunoprecipitation; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Structure-Activity Relationship

2013
Caffeic acid phenethyl ester suppresses oxidative stress in 3T3-L1 adipocytes.
    Journal of Asian natural products research, 2013, Volume: 15, Issue:11

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Caffeic Acids; Mice; Molecular Structure; Oxidative Stress; Phenylethyl Alcohol; PPAR gamma; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase

2013
Development and validation of an LCMS method to determine the pharmacokinetic profiles of caffeic acid phenethyl amide and caffeic acid phenethyl ester in male Sprague-Dawley rats.
    Biomedical chromatography : BMC, 2014, Volume: 28, Issue:2

    Topics: Animals; Caffeic Acids; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Limit of Detection; Linear Models; Male; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2014
Caffeic acid phenethyl ester prevents apoptotic cell death in the developing rat brain after pentylenetetrazole-induced status epilepticus.
    Epilepsy & behavior : E&B, 2013, Volume: 29, Issue:2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Brain; Caffeic Acids; Caspase 3; Convulsants; Disease Models, Animal; In Situ Nick-End Labeling; Male; Neurons; Neuroprotective Agents; Pentylenetetrazole; Phenylethyl Alcohol; Rats; Rats, Wistar; Status Epilepticus

2013
Theoretical, antioxidant and cytotoxic activities of caffeic acid phenethyl ester and chrysin.
    International journal of food sciences and nutrition, 2014, Volume: 65, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Caffeic Acids; Cell Proliferation; Cell Survival; Computational Biology; Flavonoids; Free Radical Scavengers; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Models, Chemical; Phenylethyl Alcohol; Quantum Theory; Structure-Activity Relationship

2014
Propolis augments apoptosis induced by butyrate via targeting cell survival pathways.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Apoptosis; Butyrates; Caffeic Acids; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Phenylethyl Alcohol; Phosphorylation; Propolis; STAT Transcription Factors

2013
Caffeic acid phenethyl ester (CAPE) protects against acute urogenital injury following pneumoperitoneum in the rat.
    Renal failure, 2014, Volume: 36, Issue:1

    Topics: Acute Kidney Injury; Animals; Caffeic Acids; Drug Evaluation, Preclinical; Genital Diseases, Male; Laparoscopy; Male; Phenylethyl Alcohol; Pneumoperitoneum, Artificial; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Testis

2014
Influence of caffeic acid phenethyl ester on bone healing in a rat model.
    The Journal of international medical research, 2013, Volume: 41, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biocompatible Materials; Bone Regeneration; Caffeic Acids; Calcium Phosphates; Fibroblasts; Injections, Intraperitoneal; Male; Osteoblasts; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Skull

2013
Impact of caffeic acid phenethyl ester treatment on vancomycin-induced pancreatic damage in rats.
    Toxicology and industrial health, 2016, Volume: 32, Issue:2

    Topics: Acute Disease; Alkaline Phosphatase; Amylases; Animals; Antioxidants; Caffeic Acids; gamma-Glutamyltransferase; Lipase; Male; Pancreas; Pancreatitis; Phenylethyl Alcohol; Rats; Rats, Wistar; Vancomycin

2016
Protective effects of caffeic acid phenethyl ester on ifosfamide-induced central neurotoxicity in rats.
    Toxicology and industrial health, 2016, Volume: 32, Issue:2

    Topics: Animals; Antioxidants; Brain; Caffeic Acids; Catalase; Ifosfamide; Immunohistochemistry; Lipid Peroxidation; Male; Malondialdehyde; Neurotoxicity Syndromes; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Protein Carbonylation; Rats; Rats, Wistar

2016
Caffeic acid phenethyl ester downregulates phospholipase D1 via direct binding and inhibition of NFκB transactivation.
    Biochemical and biophysical research communications, 2013, Dec-06, Volume: 442, Issue:1-2

    Topics: Antineoplastic Agents; Brain Neoplasms; Caffeic Acids; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; NF-kappa B; Phenylethyl Alcohol; Phospholipase D; Promoter Regions, Genetic; Propolis; Transcriptional Activation

2013
Phenolic profile and antioxidant activity of Serbian polyfloral honeys.
    Food chemistry, 2014, Feb-15, Volume: 145

    Topics: Abscisic Acid; Antioxidants; Caffeic Acids; Chlorogenic Acid; Ellagic Acid; Flavonoids; Food Analysis; Honey; Hydroxybenzoates; Phenols; Phenylethyl Alcohol; Quinic Acid; Serbia

2014
Arsenic augments the uptake of oxidized LDL by upregulating the expression of lectin-like oxidized LDL receptor in mouse aortic endothelial cells.
    Toxicology and applied pharmacology, 2013, Dec-15, Volume: 273, Issue:3

    Topics: Acetylcysteine; Animals; Aorta; Arsenites; Atherosclerosis; Caffeic Acids; Cell Line; Endothelial Cells; Lipoproteins, LDL; Mice; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Reactive Oxygen Species; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Sodium Compounds; Up-Regulation

2013
Enhanced antioxidant effect of caffeic acid phenethyl ester and Trolox in combination against radiation induced-oxidative stress.
    Chemico-biological interactions, 2014, Jan-25, Volume: 207

    Topics: Animals; Antioxidants; Biphenyl Compounds; Caffeic Acids; Cell Line; Cell Survival; Chromans; Free Radical Scavengers; Gamma Rays; Glutathione Disulfide; Lipid Peroxidation; Male; Mice; Microsomes, Liver; Oxidative Stress; Phenylethyl Alcohol; Picrates; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Thiobarbituric Acid Reactive Substances

2014
Caffeic acid phenethyl ester inhibits diesel exhaust particle-induced inflammation of human middle ear epithelial cells via NOX4 inhibition.
    The Annals of otology, rhinology, and laryngology, 2013, Volume: 122, Issue:9

    Topics: Blotting, Western; Caffeic Acids; Cells, Cultured; Epithelial Cells; Humans; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Otitis Media; Oxidative Stress; Particulate Matter; Phenylethyl Alcohol; RNA, Messenger; Up-Regulation; Vehicle Emissions

2013
Protective effects of caffeic acid phenethyl ester on the dose-dependent acute nephrotoxicity with paraquat in a rat model.
    Environmental toxicology, 2015, Volume: 30, Issue:3

    Topics: Animals; Antioxidants; Caffeic Acids; Female; Herbicides; Humans; Kidney; Kidney Diseases; Oxidation-Reduction; Paraquat; Phenylethyl Alcohol; Rats; Rats, Wistar

2015
Effect of caffeic acid phenethyl ester on myringosclerosis development in the tympanic membrane of rat.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015, Volume: 272, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Proliferation; Fibroblasts; Inflammation; Microscopy; Myringosclerosis; Otologic Surgical Procedures; Phenylethyl Alcohol; Random Allocation; Rats, Wistar; Tympanic Membrane

2015
Anticancer effects of thymoquinone, caffeic acid phenethyl ester and resveratrol on A549 non-small cell lung cancer cells exposed to benzo(a)pyrene.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzo(a)pyrene; Benzoquinones; Caffeic Acids; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cytokines; Glutathione; Humans; Lung Neoplasms; Malondialdehyde; NF-kappa B; Nitric Oxide; Phenylethyl Alcohol; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Cells, Cultured

2013
Inhibitory effects of caffeic acid phenethyl ester derivatives on replication of hepatitis C virus.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Antiviral Agents; Caffeic Acids; Hepacivirus; Phenylethyl Alcohol; RNA, Viral; Structure-Activity Relationship; Virus Replication

2013
Caffeic acid phenethyl ester attenuates pro-inflammatory and fibrogenic phenotypes of LPS-stimulated hepatic stellate cells through the inhibition of NF-κB signaling.
    International journal of molecular medicine, 2014, Volume: 33, Issue:3

    Topics: Animals; Caffeic Acids; Collagen Type I; Collagen Type I, alpha 1 Chain; Hepatic Stellate Cells; Humans; Inflammation; Lipopolysaccharides; Liver Cirrhosis; NF-kappa B; Phenylethyl Alcohol; Rats; Signal Transduction; Toll-Like Receptor 4; Transforming Growth Factor beta

2014
Structural basis for the inhibition of AKR1B10 by caffeic acid phenethyl ester (CAPE).
    ChemMedChem, 2014, Volume: 9, Issue:4

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Caffeic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Phenylethyl Alcohol; Structure-Activity Relationship

2014
CAPE promotes the expansion of human umbilical cord blood-derived hematopoietic stem and progenitor cells in vitro.
    Science China. Life sciences, 2014, Volume: 57, Issue:2

    Topics: Caffeic Acids; Cells, Cultured; Flow Cytometry; Hematopoietic Stem Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; In Vitro Techniques; Phenylethyl Alcohol; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Factor; Umbilical Cord; Up-Regulation

2014
Caffeic acid phenethyl ester, a 5-lipoxygenase enzyme inhibitor, alleviates diabetic atherosclerotic manifestations: effect on vascular reactivity and stiffness.
    Chemico-biological interactions, 2014, Apr-25, Volume: 213

    Topics: Animals; Aorta; Atherosclerosis; Blood Pressure; Body Weight; Caffeic Acids; Diabetes Complications; Immunohistochemistry; Insulin; Lipoxygenase Inhibitors; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Vascular Stiffness; Vasoconstriction

2014
A novel continuous flow biosynthesis of caffeic acid phenethyl ester from alkyl caffeate and phenethanol in a packed bed microreactor.
    Bioresource technology, 2014, Volume: 158

    Topics: Bioreactors; Caffeic Acids; Chromatography, High Pressure Liquid; Ethanol; Kinetics; Phenylethyl Alcohol; Proton Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization

2014
Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage.
    Journal of agricultural and food chemistry, 2014, May-14, Volume: 62, Issue:19

    Topics: Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Caffeic Acids; Cyclin D1; Diet, High-Fat; Down-Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mitosis; Obesity; Phenylethyl Alcohol; Propolis

2014
Caffeic acid phenethyl ester (CAPE): scavenger of peroxynitrite in vitro and in sepsis models.
    Shock (Augusta, Ga.), 2014, Volume: 42, Issue:2

    Topics: Animals; Caffeic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Free Radical Scavengers; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice, Inbred BALB C; Nitric Oxide; Peroxynitrous Acid; Phenylethyl Alcohol; Sepsis; Tyrosine

2014
Synthesis of caffeic acid phenethyl ester derivatives, and their cytoprotective and neuritogenic activities in PC12 cells.
    Journal of agricultural and food chemistry, 2014, Jun-04, Volume: 62, Issue:22

    Topics: Animals; Caffeic Acids; Hydrogen Peroxide; Molecular Structure; Neurites; PC12 Cells; Phenylethyl Alcohol; Protective Agents; Rats; Structure-Activity Relationship

2014
Effects of intrathecal caffeic acid phenethyl ester and methylprednisolone on oxidant/antioxidant status in traumatic spinal cord injuries.
    Journal of neurological surgery. Part A, Central European neurosurgery, 2015, Volume: 76, Issue:1

    Topics: Animals; Antioxidants; Caffeic Acids; Female; Injections, Spinal; Lipid Peroxidation; Methylprednisolone; Phenylethyl Alcohol; Rats; Rats, Wistar; Spinal Cord Injuries

2015
Protective effects of caffeic acid phenethyl ester (CAPE) against neomycin-induced hair cell damage in zebrafish.
    International journal of pediatric otorhinolaryngology, 2014, Volume: 78, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Caffeic Acids; Hair Cells, Auditory; Microscopy, Electron, Scanning; Mitochondria; Models, Animal; Neomycin; Phenylethyl Alcohol; Zebrafish

2014
The effects of melatonin and caffeic acid phenethyl ester (CAPE) on fracture healing under ischemic conditions.
    Acta orthopaedica et traumatologica turcica, 2014, Volume: 48, Issue:3

    Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Fracture Fixation, Intramedullary; Fracture Healing; Ischemia; Male; Melatonin; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Tibial Fractures

2014
Caffeic acid phenethyl ester promotes anti-inflammatory effects by inhibiting MAPK and NF-κB signaling in activated HMC-1 human mast cells.
    Pharmaceutical biology, 2014, Volume: 52, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Calcium; Cell Survival; Cells, Cultured; Cytokines; Histamine; Histamine Release; Humans; Hypersensitivity; Immunoglobulin E; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mast Cells; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Phenylethyl Alcohol; Phosphorylation

2014
Ganglioside GM3 is required for caffeic acid phenethyl ester-induced megakaryocytic differentiation of human chronic myelogenous leukemia K562 cells.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2014, Volume: 92, Issue:4

    Topics: Antioxidants; Caffeic Acids; Cell Differentiation; Cell Proliferation; G(M3) Ganglioside; Humans; K562 Cells; Megakaryocytes; Phenylethyl Alcohol

2014
Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Antineoplastic Agents; Caffeic Acids; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; HCT116 Cells; Humans; MAP Kinase Signaling System; Phenylethyl Alcohol

2014
Caffeic acid phenethylester increases stress resistance and enhances lifespan in Caenorhabditis elegans by modulation of the insulin-like DAF-16 signalling pathway.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caffeic Acids; DNA-Binding Proteins; Forkhead Transcription Factors; HCT116 Cells; Humans; Insulin; Longevity; Phenylethyl Alcohol; Signal Transduction; Stress, Physiological; Temperature; Transcription Factors

2014
Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester-induced apoptosis in C6 glioma cells.
    Journal of biomedical science, 2014, Jul-05, Volume: 21

    Topics: Animals; Apoptosis; Caffeic Acids; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Glioma; MAP Kinase Signaling System; Neoplasm Proteins; Phenylethyl Alcohol; Rats; Receptor, Nerve Growth Factor; Sphingomyelin Phosphodiesterase

2014
Nrf2-mediated HO-1 induction coupled with the ERK signaling pathway contributes to indirect antioxidant capacity of caffeic acid phenethyl ester in HepG2 cells.
    International journal of molecular sciences, 2014, Jul-09, Volume: 15, Issue:7

    Topics: Antioxidants; Caffeic Acids; Heme Oxygenase-1; Hep G2 Cells; Humans; MAP Kinase Signaling System; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol

2014
Caffeic acid phenethyl ester protects against amphotericin B induced nephrotoxicity in rat model.
    BioMed research international, 2014, Volume: 2014

    Topics: Amphotericin B; Animals; Anti-Bacterial Agents; Caffeic Acids; Catalase; Kidney Diseases; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Rats; Superoxide Dismutase

2014
The effect of caffeic acid phenethyl ester on isoproterenol-induced myocardial injury in hypertensive rats.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2014, Volume: 14, Issue:7

    Topics: Animals; Antioxidants; Blood Pressure; Caffeic Acids; Disease Models, Animal; Hypertension; Injections, Intraperitoneal; Isoproterenol; Lipid Peroxidation; Myocardial Infarction; Phenylethyl Alcohol; Rats

2014
Caffeic acid phenethyl ester inhibits the inflammatory effects of interleukin-1β in human corneal fibroblasts.
    Immunopharmacology and immunotoxicology, 2014, Volume: 36, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Cell Adhesion Molecules; Cell Migration Assays, Leukocyte; Cell Movement; Chemokines; Cornea; Cytokines; Fibroblasts; HL-60 Cells; Humans; Interleukin-1beta; Middle Aged; Phenylethyl Alcohol; Signal Transduction

2014
A CAPE analogue as novel antiplatelet agent efficiently inhibits collagen-induced platelet aggregation.
    Die Pharmazie, 2014, Volume: 69, Issue:8

    Topics: Animals; Blood Platelets; Caffeic Acids; Collagen; Cyclic AMP; Cyclooxygenase 1; In Vitro Techniques; Indicators and Reagents; Male; Nitric Oxide; Phenylethyl Alcohol; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Serotonin; Thromboxane B2

2014
Identification of differential proteins in colorectal cancer cells treated with caffeic acid phenethyl ester.
    World journal of gastroenterology, 2014, Sep-07, Volume: 20, Issue:33

    Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Electrophoresis, Gel, Two-Dimensional; Fluorescent Antibody Technique; Humans; Microscopy, Confocal; Neoplasm Proteins; Phenylethyl Alcohol; Proteomics; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
PI3K/Akt regulates survival during differentiation of human macrophages by maintaining NF-κB-dependent expression of antiapoptotic Bcl-xL.
    Journal of leukocyte biology, 2014, Volume: 96, Issue:6

    Topics: Anthracenes; Apoptosis; bcl-X Protein; Caffeic Acids; Cell Line, Tumor; Chromones; Flavonoids; Gene Expression Regulation, Developmental; Hematopoiesis; Humans; Macrophage Colony-Stimulating Factor; Macrophages; MAP Kinase Signaling System; Monocytes; Morpholines; NF-kappa B; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Sesquiterpenes; Signal Transduction; Tetradecanoylphorbol Acetate

2014
Inhibitory activities of propolis and its promising component, caffeic acid phenethyl ester, against amyloidogenesis of human transthyretin.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Amyloid Neuropathies, Familial; Amyloidosis; Caffeic Acids; Coumaric Acids; Masoprocol; Phenylethyl Alcohol; Prealbumin; Propolis

2014
Assesment the role of oxidative stress and efficacy of caffeic acid phenethyl ester (CAPE) on neurotoxicity induced by isoniazid and ethambutol in a rat model.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:19

    Topics: Animals; Antioxidants; Brain; Caffeic Acids; Ethambutol; Isoniazid; Male; Models, Animal; Neurotoxicity Syndromes; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Superoxide Dismutase; Treatment Outcome

2014
Effects of caffeic acid phenethyl ester on palatal mucosal defects and tooth extraction sockets.
    Drug design, development and therapy, 2014, Volume: 8

    Topics: Animals; Caffeic Acids; Male; Mouth Mucosa; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Tooth Extraction; Tooth Socket; Wound Healing

2014
Effects of caffeic acid phenethyl ester on wound healing in calvarial defects.
    Acta odontologica Scandinavica, 2015, Volume: 73, Issue:1

    Topics: Administration, Topical; Animals; Antioxidants; Bone Diseases; Bone Regeneration; Caffeic Acids; Connective Tissue; Image Processing, Computer-Assisted; Injections, Intraperitoneal; Male; NF-kappa B; Osteogenesis; Parietal Bone; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Wound Healing

2015
DFT study of the effect of solvent on the H-atom transfer involved in the scavenging of the free radicals (·)HO2 and (·)O2(-) by caffeic acid phenethyl ester and some of its derivatives.
    Journal of molecular modeling, 2014, Volume: 20, Issue:11

    Topics: Benzoates; Caffeic Acids; Computer Simulation; Coumaric Acids; Electrons; Energy Transfer; Free Radical Scavengers; Hydrogen; Kinetics; Models, Chemical; Models, Molecular; Peroxides; Phenylethyl Alcohol; Protons; Solvents; Superoxides; Temperature

2014
The radio-protective effects of caffeic acid phenethyl ester and thymoquinone in rats exposed to total head irradiation.
    Wiener klinische Wochenschrift, 2015, Volume: 127, Issue:3-4

    Topics: Animals; Benzoquinones; Caffeic Acids; Head; Liver; Liver Diseases; Phenylethyl Alcohol; Radiation Dosage; Radiation Exposure; Radiation Injuries; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Treatment Outcome

2015
Preparation of caffeic acid phenethyl ester-incorporated nanoparticles and their biological activity.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Caffeic Acids; Carcinoma; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Drug Carriers; Drug Compounding; Lung; Lung Neoplasms; Macrophages; Mice; Mice, Inbred BALB C; Micelles; Nanoparticles; Neoplasm Transplantation; Phenylethyl Alcohol; Solubility; Tumor Burden

2015
Anti-catabolic effect of caffeic acid phenethyl ester, an active component of honeybee propolis on bone loss in ovariectomized mice: a micro-computed tomography study and histological analysis.
    Chinese medical journal, 2014, Volume: 127, Issue:22

    Topics: Animals; Bone Density; Caffeic Acids; Female; Metabolism; Mice; Mice, Inbred C57BL; Ovariectomy; Phenylethyl Alcohol; Propolis; Tomography, X-Ray Computed

2014
CD133⁺ melanoma subpopulation acquired resistance to caffeic acid phenethyl ester-induced apoptosis is attributed to the elevated expression of ABCB5: significance for melanoma treatment.
    Cancer letters, 2015, Feb-01, Volume: 357, Issue:1

    Topics: AC133 Antigen; Antigens, CD; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeic Acids; Cell Line, Tumor; Drug Resistance, Neoplasm; Glycoproteins; Humans; Melanoma; Peptides; Phenylethyl Alcohol; Signal Transduction

2015
Caffeic acid phenethyl ester (CAPE) protects PC12 cells from MPP+ toxicity by inducing the expression of neuron-typical proteins.
    Neurotoxicology, 2014, Volume: 45

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Caffeic Acids; Cell Death; Cell Differentiation; Dose-Response Relationship, Drug; GAP-43 Protein; Nerve Growth Factor; Neurites; Neuroprotective Agents; PC12 Cells; Phenylethyl Alcohol; Rats; Synapsins; Synaptophysin

2014
Suppression of skin inflammation in keratinocytes and acute/chronic disease models by caffeic acid phenethyl ester.
    Archives of dermatological research, 2015, Volume: 307, Issue:3

    Topics: Acute Disease; Animals; Caffeic Acids; Cell Line; Chronic Disease; Cyclooxygenase 2; Dermatitis, Atopic; Disease Models, Animal; Humans; Immunoglobulin E; Inflammation; Keratinocytes; Mice; Mice, Inbred Strains; NF-kappa B; Oxazolone; Phenylethyl Alcohol; Propolis; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Water Loss, Insensible

2015
Protective role of caffeic acid phenethyl ester on serum cholinesterase inhibition by acute exposure to diazinon in rats.
    Turkish journal of medical sciences, 2014, Volume: 44, Issue:1

    Topics: Animals; Caffeic Acids; Cholinesterase Inhibitors; Cholinesterases; Diazinon; Insecticides; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Thermodynamics

2014
Effect of caffeic acid phenethyl ester on Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages.
    Journal of periodontal research, 2015, Volume: 50, Issue:6

    Topics: Animals; Caffeic Acids; Cytokines; Gene Expression Profiling; Immunologic Factors; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Phenylethyl Alcohol; Prevotella intermedia; Real-Time Polymerase Chain Reaction

2015
Fibrinolytic activity and dose-dependent effect of incubating human blood clots in caffeic acid phenethyl ester: in vitro assays.
    BioMed research international, 2015, Volume: 2015

    Topics: Caffeic Acids; Fibrinolysis; Humans; Microscopy, Confocal; Phenylethyl Alcohol; Thrombelastography; Thrombosis

2015
Protective effects of caffeic acid phenethyl ester against acute radiation-induced hepatic injury in rats.
    Environmental toxicology and pharmacology, 2015, Volume: 39, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeic Acids; Glutathione; Liver; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Protective Agents; Radiation Injuries, Experimental; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha; X-Rays

2015
Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation.
    European journal of pharmacology, 2015, Apr-05, Volume: 752

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeic Acids; Eye Diseases; Indomethacin; Inflammation; Male; Phenylethyl Alcohol; Rabbits

2015
Caffeic acid phenethyl ester reduces the secretion of vascular endothelial growth factor through the inhibition of the ROS, PI3K and HIF-1α signaling pathways in human retinal pigment epithelial cells under hypoxic conditions.
    International journal of molecular medicine, 2015, Volume: 35, Issue:5

    Topics: Caffeic Acids; Cell Line; Cell Survival; Epithelial Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Retinal Pigment Epithelium; Vascular Endothelial Growth Factor A

2015
Regulatory effects of caffeic acid phenethyl ester on neuroinflammation in microglial cells.
    International journal of molecular sciences, 2015, Mar-11, Volume: 16, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Caffeic Acids; Cell Line; Cyclooxygenase 2; Erythropoietin; Heme Oxygenase-1; Inflammation; Male; Mice; Mice, Inbred ICR; Microglia; Nitric Oxide Synthase Type II; Phenylethyl Alcohol

2015
Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1.
    Oncotarget, 2015, Mar-30, Volume: 6, Issue:9

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Drug Synergism; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prostatic Neoplasms, Castration-Resistant; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; RNA Interference; S-Phase Kinase-Associated Proteins; Signal Transduction; Time Factors; Transfection; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2015
An in vitro and in vivo investigation of the cytotoxic effects of caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester and bortezomib in multiple myeloma cells.
    Turkish journal of medical sciences, 2015, Volume: 45, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Interleukin-6; Mice; Mice, Inbred BALB C; Multiple Myeloma; NF-kappa B; Phenylethyl Alcohol; Pyrazines; Survival Analysis

2015
Caffeic acid phenethyl ester lessens disease symptoms in an experimental autoimmune uveoretinitis mouse model.
    Experimental eye research, 2015, Volume: 134

    Topics: Animals; Autoimmune Diseases; Blotting, Western; Caffeic Acids; Disease Models, Animal; Eye Proteins; Flow Cytometry; Immunoglobulin G; Interferon-gamma; Interleukin-6; Lymphocyte Activation; Mice; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Retinitis; Retinol-Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Tumor Necrosis Factor-alpha; Uveitis

2015
Synthesis, antitumor activity, and mechanism of action of 6-acrylic phenethyl ester-2-pyranone derivatives.
    Organic & biomolecular chemistry, 2015, Apr-28, Volume: 13, Issue:16

    Topics: Actins; Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Movement; Cytoskeleton; Esters; HeLa Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Microscopy, Fluorescence; Neoplasm Invasiveness; Phenylethyl Alcohol; Pyrones; Solubility; Structure-Activity Relationship

2015
Caffeic acid phenethyl ester abrogates bone resorption in a murine calvarial model of polyethylene particle-induced osteolysis.
    Calcified tissue international, 2015, Volume: 96, Issue:6

    Topics: Animals; Bone Resorption; Caffeic Acids; Disease Models, Animal; Female; Mice; Osteolysis; Phenylethyl Alcohol; Polyethylene; Skull; X-Ray Microtomography

2015
Caffeic acid phenethyl ester inhibits liver fibrosis in rats.
    World journal of gastroenterology, 2015, Apr-07, Volume: 21, Issue:13

    Topics: Alcohol Drinking; Animals; Antioxidants; Biomarkers; Caffeic Acids; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Diet, High-Fat; Dose-Response Relationship, Drug; Hepatic Stellate Cells; Liver; Liver Cirrhosis, Experimental; Male; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol; Rats, Sprague-Dawley

2015
The effects of Nigella sativa oil, thymoquinone, propolis, and caffeic acid phenethyl ester on radiation-induced cataract.
    Wiener klinische Wochenschrift, 2016, Volume: 128, Issue:Suppl 8

    Topics: Animals; Antioxidants; Benzoquinones; Caffeic Acids; Cataract; Cranial Irradiation; Dose-Response Relationship, Drug; Male; Phenylethyl Alcohol; Plant Oils; Propolis; Radiation Injuries; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Treatment Outcome

2016
The effects of caffeic acid phenethyl ester on inflammatory cytokines after acute spinal cord injury.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2015, Volume: 21, Issue:2

    Topics: Animals; Caffeic Acids; Cytokines; Interleukin-1beta; Male; Neuroprotective Agents; Phenylethyl Alcohol; Rats; Rats, Wistar; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2015
Inhibitory effects of hydroxylated cinnamoyl esters on lipid absorption and accumulation.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: 3T3-L1 Cells; Animals; Anti-Obesity Agents; Caffeic Acids; Catechols; Cell Differentiation; Corn Oil; Dose-Response Relationship, Drug; Intestinal Absorption; Lipase; Mice; Obesity; Pancreas; Phenylethyl Alcohol; Structure-Activity Relationship; Swine; Triglycerides

2015
Value of caffeic acid phenethyl ester pretreatment in experimental sepsis model in rats.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Animals; Caffeic Acids; Disease Models, Animal; Endothelin-1; Inflammation; Male; Malondialdehyde; Oxidative Stress; Oxygen; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Sepsis; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha

2015
The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of d-galactosamine-induced acute hepatitis in rats.
    Human & experimental toxicology, 2016, Volume: 35, Issue:4

    Topics: Animals; Caffeic Acids; Caspase 3; Chemical and Drug Induced Liver Injury; Galactosamine; Glycogen; Ki-67 Antigen; Liver; Male; Malondialdehyde; Mast Cells; Pentoxifylline; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar

2016
Caffeic Acid phenethyl ester and ethanol extract of propolis induce the complementary cytotoxic effect on triple-negative breast cancer cell lines.
    Molecules (Basel, Switzerland), 2015, May-20, Volume: 20, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caffeic Acids; Cell Line, Tumor; Female; Humans; Phenylethyl Alcohol; Phytotherapy; Propolis; Triple Negative Breast Neoplasms

2015
Sonoran propolis and some of its chemical constituents inhibit in vitro growth of Giardia lamblia trophozoites.
    Planta medica, 2015, Volume: 81, Issue:9

    Topics: Animals; Caffeic Acids; Cell Proliferation; Flavonoids; Giardia lamblia; Mexico; Phenylethyl Alcohol; Propolis; Rutin; Trophozoites

2015
The effects of caffeic acid phenethyl ester (CAPE) on bacterial translocation and inflammatory response in an experimental intestinal obstruction model in rats.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Bacterial Translocation; Caffeic Acids; Disease Models, Animal; Inflammation Mediators; Injections, Intraperitoneal; Intestinal Mucosa; Intestinal Obstruction; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2015
In vitro effect of caffeic acid phenethyl ester on matrix metalloproteinases (MMP-1 and MMP-9) and their inhibitor (TIMP-1) in lipopolysaccharide-activated human monocytes.
    Archives of oral biology, 2015, Volume: 60, Issue:9

    Topics: Caffeic Acids; Cell Line; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Lipopolysaccharides; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Monocytes; Phenylethyl Alcohol; Real-Time Polymerase Chain Reaction; Tissue Inhibitor of Metalloproteinase-1

2015
Caffeic acid phenethyl ester attenuates ionize radiation-induced intestinal injury through modulation of oxidative stress, apoptosis and p38MAPK in rats.
    Environmental toxicology and pharmacology, 2015, Volume: 40, Issue:1

    Topics: Animals; Apoptosis; Caffeic Acids; Intestinal Mucosa; Intestines; Male; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Radiation, Ionizing; Rats; Rats, Sprague-Dawley

2015
CAPE Analogs Induce Growth Arrest and Apoptosis in Breast Cancer Cells.
    Molecules (Basel, Switzerland), 2015, Jul-10, Volume: 20, Issue:7

    Topics: Apoptosis; Biphenyl Compounds; Caffeic Acids; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Female; Free Radicals; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Inhibitory Concentration 50; Luciferases; MCF-7 Cells; Mutation; Phenylethyl Alcohol; Picrates; Signal Transduction; Structure-Activity Relationship; Tumor Suppressor Protein p53

2015
Dengue Virus Infection Causes the Activation of Distinct NF-κB Pathways for Inducible Nitric Oxide Synthase and TNF-α Expression in RAW264.7 Cells.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Animals; Caffeic Acids; Cell Line; Dengue Virus; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Signal Transduction; Tumor Necrosis Factor-alpha

2015
Protective Effects of Caffeic Acid Phenethyl Ester on Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats.
    Journal of biochemical and molecular toxicology, 2015, Volume: 29, Issue:12

    Topics: Animals; Antineoplastic Agents, Alkylating; Caffeic Acids; Catalase; Cyclophosphamide; Cystitis; Hemorrhage; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase; Urinary Bladder

2015
Caffeic acid phenethyl ester protects lung alveolar epithelial cells from cigarette smoke-induced damage.
    Turkish journal of medical sciences, 2015, Volume: 45, Issue:3

    Topics: Antioxidants; Caffeic Acids; Cell Death; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cytokines; Epithelial Cells; Humans; Inflammation; Lipid Peroxidation; Lung; Nicotiana; Oxidative Stress; Phenylethyl Alcohol; Pulmonary Alveoli; Real-Time Polymerase Chain Reaction; Respiratory Mucosa; RNA; Smoking

2015
Caffeic acid phenethyl ester inhibits 3-MC-induced CYP1A1 expression through induction of hypoxia-inducible factor-1α.
    Biochemical and biophysical research communications, 2015, Sep-25, Volume: 465, Issue:3

    Topics: Animals; Apoptosis; Caffeic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Hypoxia-Inducible Factor 1, alpha Subunit; Methylcholanthrene; Mice; Phenylethyl Alcohol

2015
Combination of immunoprecipitation (IP)-ATP_Glo kinase assay and melanogenesis for the assessment of potent and safe PAK1-blockers in cell culture.
    Drug discoveries & therapeutics, 2015, Volume: 9, Issue:4

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Humans; Immunoprecipitation; Melanins; Mice; p21-Activated Kinases; Phenylethyl Alcohol; Protein Kinase Inhibitors; Reagent Kits, Diagnostic; Triterpenes

2015
Inhibition of Survival Pathways MAPK and NF-kB Triggers Apoptosis in Pancreatic Ductal Adenocarcinoma Cells via Suppression of Autophagy.
    Targeted oncology, 2016, Volume: 11, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Butadienes; Caffeic Acids; Carcinoma, Pancreatic Ductal; Cell Growth Processes; Cell Line, Tumor; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Nitriles; Pancreatic Neoplasms; Phenylethyl Alcohol; Protein Kinase Inhibitors; Survival Rate

2016
Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Sep-17, Volume: 21

    Topics: Animals; Caffeic Acids; Cystathionine gamma-Lyase; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Hydrogen Sulfide; Immunohistochemistry; Liver; Liver Cirrhosis; Male; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2015
Anti-Apoptotic and Anti-Oxidant Effects of Caffeic Acid Phenethyl Ester on Cadmium-Induced Testicular Toxicity in Rats.
    Biological trace element research, 2016, Volume: 171, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Cadmium; Caffeic Acids; Male; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Testis

2016
The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis.
    Cell and tissue research, 2016, Volume: 363, Issue:3

    Topics: Actins; Adult; Caffeic Acids; Cell Nucleus; Collagen Type I; Fibroblasts; Fibronectins; Fibrosis; Gene Expression Regulation; Humans; Microfilament Proteins; Muscle Proteins; Myofibroblasts; Phenylethyl Alcohol; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase; Protein Transport; RNA, Messenger; Smad Proteins; Tenascin; Transcription Factors; Transforming Growth Factor beta1; Young Adult

2016
The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII.
    Journal of enzyme inhibition and medicinal chemistry, 2016, Volume: 31, Issue:6

    Topics: Acetylcholinesterase; Butyrylcholinesterase; Caffeic Acids; Carbonic Anhydrases; Glutathione Transferase; Isoenzymes; Lactoperoxidase; Phenylethyl Alcohol

2016
Effects of Caffeic Acid Phenethyl Ester and 4-Vinylcatechol on the Stabilities of Oil-in-Water Emulsions of Stripped Soybean Oil.
    Journal of agricultural and food chemistry, 2015, Dec-02, Volume: 63, Issue:47

    Topics: Antioxidants; Caffeic Acids; Catechols; Emulsions; Molecular Structure; Oxidation-Reduction; Phenylethyl Alcohol; Soybean Oil

2015
Effects of caffeic acid phenethyl ester on matrix molecules and angiogenetic and anti-angiogenetic factors in gastric cancer cells cultured on different substrates.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2016, Volume: 91, Issue:1

    Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Phenylethyl Alcohol; Stomach Neoplasms

2016
Anti-Neoplastic and Calcium Modulatory Action of Caffeic Acid Phenethyl Ester and Dasatinib in C6 Glial Cells: A Therapeutic Perspective.
    CNS & neurological disorders drug targets, 2016, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Calcium; Cell Death; Cell Line, Tumor; Dasatinib; Glioma; Neuroglia; Phenylethyl Alcohol; Rats

2016
Comparative evaluation of antibacterial activity of caffeic acid phenethyl ester and PLGA nanoparticle formulation by different methods.
    Nanotechnology, 2016, Jan-15, Volume: 27, Issue:2

    Topics: Anti-Bacterial Agents; Caffeic Acids; Capsules; Chemistry, Pharmaceutical; Drug Delivery Systems; Escherichia coli; Lactic Acid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nanoparticles; Particle Size; Phenylethyl Alcohol; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Staphylococcus aureus

2016
Antioxidant Properties of Caffeic acid Phenethyl Ester and 4-Vinylcatechol in Stripped Soybean Oil.
    Journal of food science, 2016, Volume: 81, Issue:1

    Topics: alpha-Tocopherol; Antioxidants; Caffeic Acids; Catechols; Hydrogen Peroxide; Oxidation-Reduction; Peroxides; Phenylethyl Alcohol; Soybean Oil

2016
The role of CAPE in PI3K/AKT/mTOR activation and oxidative stress on testis torsion.
    Acta histochemica, 2016, Volume: 118, Issue:1

    Topics: Animals; Antioxidants; Caffeic Acids; Drug Evaluation, Preclinical; Male; Oxidative Stress; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Spermatic Cord Torsion; Testis; TOR Serine-Threonine Kinases

2016
Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Beclin-1; Breast Neoplasms; Caffeic Acids; Female; Humans; MCF-7 Cells; Membrane Proteins; Microtubule-Associated Proteins; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2; Tamoxifen

2016
Caffeic acid phenethyl ester: Inhibition of metastatic cell behaviours via voltage-gated sodium channel in human breast cancer in vitro.
    The international journal of biochemistry & cell biology, 2016, Volume: 71

    Topics: Antineoplastic Agents; Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Electrophysiological Phenomena; Humans; Neoplasm Metastasis; Phenylethyl Alcohol; Voltage-Gated Sodium Channels

2016
Effect of caffeic acid phenethyl ester on bone formation in the expanded inter-premaxillary suture.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Caffeic Acids; Injections, Intraperitoneal; Male; Osteogenesis; Palatal Expansion Technique; Palate, Hard; Phenylethyl Alcohol; Rats, Sprague-Dawley; Time Factors

2015
The Effect of Caffeic Acid Phenethyl Ester (CAPE) Fortification on the Liver Element Distribution that Occurs After Exercise.
    Biological trace element research, 2016, Volume: 172, Issue:2

    Topics: Animals; Cadmium; Caffeic Acids; Calcium; Chromium; Copper; Injections, Intraperitoneal; Iron; Liver; Magnesium; Male; Phenylethyl Alcohol; Physical Conditioning, Animal; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Tissue Distribution; Zinc

2016
Caffeic acid phenethyl ester exhibiting distinctive binding interaction with human serum albumin implies the pharmacokinetic basis of propolis bioactive components.
    Journal of pharmaceutical and biomedical analysis, 2016, Apr-15, Volume: 122

    Topics: Caffeic Acids; Circular Dichroism; Fluorescence Resonance Energy Transfer; Humans; Hydrogen Bonding; Molecular Docking Simulation; Phenylethyl Alcohol; Propolis; Protein Binding; Protein Structure, Secondary; Serum Albumin; Spectrometry, Fluorescence; Thermodynamics

2016
Caffeic acid phenethyl ester activates pro-apoptotic and epithelial-mesenchymal transition-related genes in ovarian cancer cells A2780 and A2780cis.
    Molecular and cellular biochemistry, 2016, Volume: 413, Issue:1-2

    Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Ovarian Neoplasms; Phenylethyl Alcohol

2016
The Protective Effects of Caffeic Acid Phenethyl Ester on Acetylsalicylic Acid-induced Lung Injury in Rats.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2016, Volume: 29, Issue:6

    Topics: Animals; Aspirin; Caffeic Acids; Drug Evaluation, Preclinical; Female; Lung; Lung Injury; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats, Wistar

2016
Activation of NF-κB and AP-1 Mediates Hyperproliferation by Inducing β-Catenin and c-Myc in Helicobacter pylori-Infected Gastric Epithelial Cells.
    Yonsei medical journal, 2016, Volume: 57, Issue:3

    Topics: beta Catenin; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; DNA, Bacterial; Epithelial Cells; Gastric Mucosa; Gastritis; Gene Expression Regulation, Bacterial; Helicobacter Infections; Helicobacter pylori; Humans; NF-kappa B; Peptide Fragments; Phenylethyl Alcohol; Proto-Oncogene Proteins c-jun; Repressor Proteins; Transcription Factor AP-1; Transcription Factors

2016
Could Caffeic Acid Phenethyl Ester Expand the Antitumor Effect of Tamoxifen in Breast Carcinoma?
    Nutrition and cancer, 2016, Volume: 68, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Caffeic Acids; Carcinoma, Ehrlich Tumor; Caspase 3; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Phenylethyl Alcohol; Proteins; Tamoxifen; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2016
Effect of Caffeic Acid Phenethyl Ester on Vascular Damage Caused by Consumption of High Fructose Corn Syrup in Rats.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Caffeic Acids; High Fructose Corn Syrup; In Vitro Techniques; Nitric Oxide Synthase Type III; Phenylephrine; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Vascular Diseases; Vascular Resistance; Vasodilation

2016
Effect of caffeic acid phenethyl ester on oxidant and anti-oxidant status of liver and serum in a rat model with acute methanol intoxication.
    Irish journal of medical science, 2017, Volume: 186, Issue:2

    Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Ethanol; Liver; Male; Methanol; Methotrexate; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2017
Protective Effects of Caffeic Acid Phenethyl Ester on Fluoxetine-Induced Hepatotoxicity: An Experimental Study.
    BioMed research international, 2016, Volume: 2016

    Topics: Animals; Antioxidants; Aryldialkylphosphatase; Caffeic Acids; Chemical and Drug Induced Liver Injury; Fluoxetine; Male; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2016
In vitro CAPE inhibitory activity towards human AKR1C3 and the molecular basis.
    Chemico-biological interactions, 2016, Jun-25, Volume: 253

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Binding Sites; Caffeic Acids; Crystallography, X-Ray; Humans; Hydroxybenzoates; Hydroxyprostaglandin Dehydrogenases; Male; Phenylethyl Alcohol; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Protein Structure, Tertiary

2016
Effects of Oxidative Stress and Testosterone on Pro-Inflammatory Signaling in a Female Rat Dopaminergic Neuronal Cell Line.
    Endocrinology, 2016, Volume: 157, Issue:7

    Topics: Animals; Apoptosis; Caffeic Acids; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dopaminergic Neurons; Female; Ibuprofen; Inflammation; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Signal Transduction; Testosterone

2016
CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling.
    Oncotarget, 2016, Jun-21, Volume: 7, Issue:25

    Topics: Animals; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Phenylethyl Alcohol; Prostatic Neoplasms; Transfection; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2016
The effects of caffeic acid phenethyl ester on streptozotocin-induced diabetic liver injury.
    Bratislavske lekarske listy, 2016, Volume: 117, Issue:5

    Topics: Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Glutathione; Liver; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase

2016
Caffeic acid phenethyl ester enhances TRAIL-mediated apoptosis via CHOP-induced death receptor 5 upregulation in hepatocarcinoma Hep3B cells.
    Molecular and cellular biochemistry, 2016, Volume: 418, Issue:1-2

    Topics: Apoptosis; Caffeic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Neoplasm Proteins; Phenylethyl Alcohol; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor CHOP; Up-Regulation

2016
Protective Effects of Intralipid and Caffeic Acid Phenethyl Ester (CAPE) on Hepatotoxicity and Pancreatic Injury Caused by Dichlorvos in Rats.
    Biochemical genetics, 2016, Volume: 54, Issue:6

    Topics: Animals; Caffeic Acids; Chemical and Drug Induced Liver Injury; Dichlorvos; Emulsions; Gene Expression Regulation; Male; Oxidative Stress; Pancreatic Diseases; Phenylethyl Alcohol; Phospholipids; Rats; Rats, Wistar; Soybean Oil; Treatment Outcome

2016
Neuroprotective effects of caffeic acid phenethyl ester against sevoflurane‑induced neuronal degeneration in the hippocampus of neonatal rats involve MAPK and PI3K/Akt signaling pathways.
    Molecular medicine reports, 2016, Volume: 14, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Caffeic Acids; Female; Hippocampus; MAP Kinase Signaling System; Methyl Ethers; Neurodegenerative Diseases; Neuroprotective Agents; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Sevoflurane; Signal Transduction

2016
Fabrication of Novel Bioactive Cellulose-Based Films Derived from Caffeic Acid Phenethyl Ester-Loaded Nanoparticles via a Rapid Expansion Process: RESOLV.
    Journal of agricultural and food chemistry, 2016, Sep-07, Volume: 64, Issue:35

    Topics: Anti-Infective Agents; Antioxidants; Bacteria; Caffeic Acids; Cellulose; Food Packaging; Microbial Sensitivity Tests; Nanoparticles; Particle Size; Phenylethyl Alcohol; Yeasts

2016
Protective Effects of Intralipid and Caffeic Acid Phenyl Esther (CAPE) on Neurotoxicity Induced by Ethanol in Rats.
    Turkish neurosurgery, 2017, Volume: 27, Issue:1

    Topics: Animals; Antioxidants; Brain; Caffeic Acids; Cerebellum; Emulsions; Ethanol; Male; Neuroprotective Agents; Oxidative Stress; Phenylethyl Alcohol; Phospholipids; Rats; Soybean Oil

2017
Structure-activity relationship of caffeic acid phenethyl ester analogs as new 5-lipoxygenase inhibitors.
    Chemical biology & drug design, 2017, Volume: 89, Issue:4

    Topics: Caffeic Acids; Carbon-13 Magnetic Resonance Spectroscopy; Free Radical Scavengers; HEK293 Cells; Humans; Lipoxygenase Inhibitors; Mass Spectrometry; Molecular Docking Simulation; Neutrophils; Phenylethyl Alcohol; Proton Magnetic Resonance Spectroscopy; Structure-Activity Relationship; Thapsigargin

2017
Caffeic acid phenethyl ester alleviates asthma by regulating the airway microenvironment via the ROS-responsive MAPK/Akt pathway.
    Free radical biology & medicine, 2016, Volume: 101

    Topics: Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Caffeic Acids; Chemokine CCL11; Chemokine CCL2; Female; Gene Expression Regulation; Humans; Immunoglobulin E; Intercellular Adhesion Molecule-1; Interleukin-13; Interleukin-4; Lung; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Ovalbumin; Phenylethyl Alcohol; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2016
Role of CAPE on cardiomyocyte protection via connexin 43 regulation under hypoxia.
    International journal of medical sciences, 2016, Volume: 13, Issue:10

    Topics: Caffeic Acids; Cell Line; Connexin 43; Humans; Hypoxia; L-Lactate Dehydrogenase; Mitochondria, Heart; Myocardial Ischemia; Myocytes, Cardiac; Phenylethyl Alcohol

2016
Caffeic acid phenethyl ester attenuates lipopolysaccharide-stimulated proinflammatory responses in human gingival fibroblasts via NF-κB and PI3K/Akt signaling pathway.
    European journal of pharmacology, 2017, Jan-05, Volume: 794

    Topics: Active Transport, Cell Nucleus; Anti-Inflammatory Agents; Caffeic Acids; Cell Nucleus; Enzyme Activation; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Inflammation; Inflammation Mediators; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Myeloid Differentiation Factor 88; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Toll-Like Receptor 4; Transcription Factor RelA

2017
Caffeic acid phenethyl ester (CAPE) revisited: Covalent modulation of XPO1/CRM1 activities and implication for its mechanism of action.
    Chemical biology & drug design, 2017, Volume: 89, Issue:5

    Topics: Binding Sites; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Exportin 1 Protein; HeLa Cells; Humans; Karyopherins; Mass Spectrometry; MCF-7 Cells; Microscopy, Confocal; Molecular Dynamics Simulation; Peptides; Phenylethyl Alcohol; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship

2017
Targeting ASC in NLRP3 inflammasome by caffeic acid phenethyl ester: a novel strategy to treat acute gout.
    Scientific reports, 2016, 12-09, Volume: 6

    Topics: Administration, Oral; Animals; Biomarkers; Caffeic Acids; CARD Signaling Adaptor Proteins; Disease Models, Animal; Gout; Inflammasomes; Liquid Crystals; Macrophages; Mice; Models, Molecular; Molecular Conformation; NLR Family, Pyrin Domain-Containing 3 Protein; Phenylethyl Alcohol; Protein Binding; Uric Acid

2016
Bone resorption, matrix metalloproteinases and caffeic acid phenethyl ester.
    Acta orthopaedica et traumatologica turcica, 2016, Volume: 50, Issue:6

    Topics: Biomarkers; Bone Resorption; Caffeic Acids; Humans; Matrix Metalloproteinases; Osteoporosis; Phenylethyl Alcohol

2016
Attenuating effects of caffeic acid phenethyl ester with intralipid on hepatotoxicity of chlorpyrifos in the case of rats.
    Medycyna pracy, 2016, Dec-22, Volume: 67, Issue:6

    Topics: Animals; Antioxidants; Caffeic Acids; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Immunochemistry; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2016
Mixed effects of caffeic acid phenethyl ester (CAPE) on joint inflammation, bone loss and gastrointestinal inflammation in a murine model of collagen antibody-induced arthritis.
    Inflammopharmacology, 2017, Volume: 25, Issue:1

    Topics: Animals; Arthritis, Experimental; Bone Resorption; Caffeic Acids; Collagen; Gastrointestinal Tract; Inflammation; Joints; Mice; Mice, Inbred BALB C; Phenylethyl Alcohol; Random Allocation; Tomography, X-Ray Computed; Treatment Outcome

2017
HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis.
    Journal of neuroinflammation, 2017, 01-26, Volume: 14, Issue:1

    Topics: Adult; Astrocytes; Caffeic Acids; Complement C3; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Female; Fetus; Gene Expression Regulation; Gene Expression Regulation, Viral; Glial Fibrillary Acidic Protein; HIV Infections; Humans; Interleukin-6; Male; Middle Aged; NF-kappa B; Phenylethyl Alcohol; Promoter Regions, Genetic; Signal Transduction

2017
The effects of pollen, propolis, and caffeic acid phenethyl ester on tyrosine hydroxylase activity and total RNA levels in hypertensive rats caused by nitric oxide synthase inhibition: experimental, docking and molecular dynamic studies.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:3

    Topics: Adrenal Medulla; Animals; Caffeic Acids; Catalytic Domain; Catecholamines; Disease Models, Animal; Heart; Humans; Hypertension; Hypothalamus; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylethyl Alcohol; Pollen; Propolis; Rats; Tyrosine 3-Monooxygenase

2018
Relevance of mortalin to cancer cell stemness and cancer therapy.
    Scientific reports, 2017, 02-06, Volume: 7

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Caffeic Acids; Cell Line; Cell Line, Tumor; HSP70 Heat-Shock Proteins; Humans; Neoplasms; Neoplastic Stem Cells; Phenylethyl Alcohol; Pyridines; RNA, Small Interfering; Thiazoles; Up-Regulation

2017
Caffeic acid phenethyl ester upregulates N-myc downstream regulated gene 1 via ERK pathway to inhibit human oral cancer cell growth in vitro and in vivo.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:9

    Topics: Animals; Caffeic Acids; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mouth Neoplasms; Phenylethyl Alcohol; Promoter Regions, Genetic; Squamous Cell Carcinoma of Head and Neck; Up-Regulation; Xenograft Model Antitumor Assays

2017
Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-1.
    Current pharmaceutical design, 2017, Volume: 23, Issue:18

    Topics: Animals; Antioxidants; Caffeic Acids; Cell Survival; Cells, Cultured; Enzyme Induction; Heme Oxygenase-1; Humans; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2017
Caffeic acid phenethyl ester attenuates liver fibrosis via inhibition of TGF-β1/Smad3 pathway and induction of autophagy pathway.
    Biochemical and biophysical research communications, 2017, 04-22, Volume: 486, Issue:1

    Topics: Actins; Animals; Autophagosomes; Autophagy; Blotting, Western; Caffeic Acids; Carbon Tetrachloride; Cell Line; Collagen Type I; Dose-Response Relationship, Drug; Gene Expression; Hepatic Stellate Cells; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Phenylethyl Alcohol; Phosphorylation; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad3 Protein; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1

2017
An Intestinal Farnesoid X Receptor-Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice.
    Diabetes, 2017, Volume: 66, Issue:3

    Topics: Acetyl Coenzyme A; Amidohydrolases; Animals; Body Weight; Caffeic Acids; Ceramides; Diet, High-Fat; Gastrointestinal Microbiome; Gluconeogenesis; Ileum; Insulin; Intestinal Mucosa; Intestines; Isoxazoles; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Phenylethyl Alcohol; Pyruvate Carboxylase; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Taurocholic Acid

2017
NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting "stemness".
    Oncotarget, 2017, Mar-28, Volume: 8, Issue:13

    Topics: Antineoplastic Agents; Ascorbic Acid; Biomarkers, Tumor; Caffeic Acids; Cell Proliferation; Dioxolanes; Flow Cytometry; Humans; MCF-7 Cells; NAD; Neoplastic Stem Cells; Optical Imaging; Phenylethyl Alcohol

2017
Caffeic acid phenethyl ester up-regulates antioxidant levels in hepatic stellate cell line T6
    World journal of gastroenterology, 2017, Feb-21, Volume: 23, Issue:7

    Topics: Animals; Antioxidants; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Hepatic Stellate Cells; Immunoenzyme Techniques; MAP Kinase Signaling System; Microscopy, Fluorescence; NF-E2-Related Factor 2; Oxidative Stress; Phenol; Phenylethyl Alcohol; Protein Transport; Rats; Reactive Oxygen Species

2017
Direct interaction between caffeic acid phenethyl ester and human neutrophil elastase inhibits the growth and migration of PANC-1 cells.
    Oncology reports, 2017, Volume: 37, Issue:5

    Topics: alpha 1-Antitrypsin; Caffeic Acids; Carcinoma, Pancreatic Ductal; Catalytic Domain; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Leukocyte Elastase; Models, Molecular; Molecular Dynamics Simulation; Pancreatic Neoplasms; Phenylethyl Alcohol

2017
Caffeic acid phenethyl ester protects against glucocorticoid-induced osteoporosis in vivo: Impact on oxidative stress and RANKL/OPG signals.
    Toxicology and applied pharmacology, 2017, 06-01, Volume: 324

    Topics: Animals; Caffeic Acids; Glucocorticoids; Male; Osteoporosis; Osteoprotegerin; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; RANK Ligand; Rats; Rats, Sprague-Dawley

2017
The effect of caffeic acid phenethyl ester and thymoquinone on otitis media with effusion in rats.
    International journal of pediatric otorhinolaryngology, 2017, Volume: 96

    Topics: Animals; Anti-Inflammatory Agents; Benzoquinones; Caffeic Acids; Disease Models, Animal; Eustachian Tube; Injections, Intraperitoneal; Male; Otitis Media with Effusion; Phenylethyl Alcohol; Rats; Rats, Wistar; Temporal Bone

2017
Neuroprotective effect of three caffeic acid derivatives via ameliorate oxidative stress and enhance PKA/CREB signaling pathway.
    Behavioural brain research, 2017, 06-15, Volume: 328

    Topics: Animals; Avoidance Learning; Caffeic Acids; Cell Survival; Curcumin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Galactose; Hydrogen Peroxide; Lactates; Maze Learning; Mice; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Phenylethyl Alcohol; Random Allocation; Rats; Signal Transduction; Spatial Memory

2017
Caffeic acid phenethyl ester attenuates pathological cardiac hypertrophy by regulation of MEK/ERK signaling pathway in vivo and vitro.
    Life sciences, 2017, Jul-15, Volume: 181

    Topics: Animals; Blotting, Western; Caffeic Acids; Cardiomegaly; Cell Line; Disease Models, Animal; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Phenylephrine; Phenylethyl Alcohol; Polymerase Chain Reaction; Rats; Resveratrol; Smad Proteins; Stilbenes; Transforming Growth Factor beta

2017
Caffeic acid phenethyl ester protects the brain against hexavalent chromium toxicity by enhancing endogenous antioxidants and modulating the JAK/STAT signaling pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 91

    Topics: Acetylcholinesterase; Animals; Antioxidants; Caffeic Acids; Cerebrum; Chromium; Down-Regulation; Glutathione; Glutathione Peroxidase; Inflammation; Janus Kinases; Lipid Peroxidation; Male; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Phosphorylation; Rats, Wistar; RNA, Messenger; Signal Transduction; STAT Transcription Factors; Superoxide Dismutase; Suppressor of Cytokine Signaling 3 Protein

2017
Is caffeic acid phenethyl ester more protective than doxycycline in experimental periodontitis?
    Archives of oral biology, 2017, Volume: 81

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caffeic Acids; Cytokines; Disease Models, Animal; Doxycycline; Enzyme-Linked Immunosorbent Assay; Lipid Peroxidation; Male; Oxidants; Oxidative Stress; Periodontitis; Phenylethyl Alcohol; Rats; Rats, Wistar

2017
Synergistic antitumor effect of NVP-BEZ235 and CAPE on MDA-MB-231 breast cancer cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Female; Forkhead Box Protein O3; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Neoplasm Proteins; Phenylethyl Alcohol; Phosphorylation; Protein Processing, Post-Translational; Quinolines; Receptors, CXCR4; Triple Negative Breast Neoplasms

2017
Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function.
    Inflammopharmacology, 2018, Volume: 26, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Colitis, Ulcerative; Cytokines; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Female; Inflammation; Inflammation Mediators; Mice, Inbred C57BL; NF-kappa B; Phenylethyl Alcohol; Protective Agents

2018
The effect of caffeic acid phenethyl ester (CAPE) on tympanosclerosis.
    International journal of pediatric otorhinolaryngology, 2017, Volume: 95

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Inflammation; Male; Middle Ear Ventilation; Myringosclerosis; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Tympanic Membrane

2017
New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis.
    Mediators of inflammation, 2017, Volume: 2017

    Topics: Arachidonate 5-Lipoxygenase; Caffeic Acids; Coumaric Acids; Enzyme Activation; Hydroxyurea; Leukotrienes; Lipoxygenase Inhibitors; Phenylethyl Alcohol; Structure-Activity Relationship

2017
3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells.
    Journal of cellular physiology, 2018, Volume: 233, Issue:2

    Topics: Autophagy; Caffeic Acids; Cell Line, Tumor; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Neurons; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Phenylethyl Alcohol; Signal Transduction; Time Factors; Unfolded Protein Response

2018
Caffeic Acid Phenethyl Ester from the Twigs of Cinnamomum cassia Inhibits Malignant Cell Transformation by Inducing c-Fos Degradation.
    Journal of natural products, 2017, 07-28, Volume: 80, Issue:7

    Topics: Anticarcinogenic Agents; Caffeic Acids; Cinnamomum aromaticum; Molecular Structure; Phenylethyl Alcohol; Plant Stems; Proto-Oncogene Proteins c-fos; Republic of Korea; Signal Transduction; Transcription Factor AP-1

2017
Substituted Caffeic and Ferulic Acid Phenethyl Esters: Synthesis, Leukotrienes Biosynthesis Inhibition, and Cytotoxic Activity.
    Molecules (Basel, Switzerland), 2017, Jul-06, Volume: 22, Issue:7

    Topics: Arachidonate 5-Lipoxygenase; Caffeic Acids; Cell Death; Cell Line, Tumor; Cell Survival; Coumaric Acids; HEK293 Cells; Humans; Imaging, Three-Dimensional; Leukotrienes; Ligands; Lipoxygenase Inhibitors; Molecular Docking Simulation; Phenylethyl Alcohol; Thermodynamics

2017
Metabolomics study of cadmium-induced diabetic nephropathy and protective effect of caffeic acid phenethyl ester using UPLC-Q-TOF-MS combined with pattern recognition.
    Environmental toxicology and pharmacology, 2017, Volume: 54

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Cadmium; Caffeic Acids; Catalase; Diabetic Nephropathies; Glutathione; Kidney; Lipid Metabolism; Male; Metabolomics; Mice; Oxidative Stress; Pattern Recognition, Automated; Phenylethyl Alcohol; Superoxide Dismutase; Tandem Mass Spectrometry

2017
Caffeic Acid Phenethyl Ester (Propolis Extract) Ameliorates Insulin Resistance by Inhibiting JNK and NF-κB Inflammatory Pathways in Diabetic Mice and HepG2 Cell Models.
    Journal of agricultural and food chemistry, 2017, Oct-18, Volume: 65, Issue:41

    Topics: Animals; Caffeic Acids; Diabetes Mellitus, Type 2; Glucose-6-Phosphatase; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Phenylethyl Alcohol; Propolis; Signal Transduction

2017
Effects of propolis, caffeic acid phenethyl ester, and pollen on renal injury in hypertensive rat: An experimental and theoretical approach.
    Cell biochemistry and function, 2017, Volume: 35, Issue:6

    Topics: Animals; Antioxidants; Arginine; Aryldialkylphosphatase; Binding Sites; Caffeic Acids; Glutathione Reductase; Half-Life; Hypertension; Kidney Diseases; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol; Pollen; Propolis; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley

2017
Glycosylation Enhances the Physicochemical Properties of Caffeic Acid Phenethyl Ester.
    Journal of microbiology and biotechnology, 2017, Nov-28, Volume: 27, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Caffeic Acids; Cell Survival; Deinococcus; Enzyme Stability; Gene Expression Regulation; Glucosyltransferases; Glycosides; Glycosylation; Hydrogen-Ion Concentration; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Mice; NF-E2-Related Factor 2; Nitric Oxide; Phenylethyl Alcohol; RAW 264.7 Cells; Solubility; Temperature

2017
Concurrent treatment with simvastatin and NF-κB inhibitor in human castration-resistant prostate cancer cells exerts synergistic anti-cancer effects via control of the NF-κB/LIN28/let-7 miRNA signaling pathway.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; NF-kappa B; Phenylethyl Alcohol; Prostatic Neoplasms, Castration-Resistant; RNA-Binding Proteins; Signal Transduction; Simvastatin

2017
Protective Effect of Combined Caffeic Acid Phenethyl Ester and Bevacizumab Against Hydrogen Peroxide-Induced Oxidative Stress in Human RPE Cells.
    Current eye research, 2017, Volume: 42, Issue:12

    Topics: Angiogenesis Inhibitors; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Bevacizumab; Caffeic Acids; Caspase 3; Cell Line; Cell Survival; Cytochromes c; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Hydrogen Peroxide; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Retinal Pigment Epithelium; Vascular Endothelial Growth Factor A

2017
Ethanol extract of propolis and its constituent caffeic acid phenethyl ester inhibit breast cancer cells proliferation in inflammatory microenvironment by inhibiting TLR4 signal pathway and inducing apoptosis and autophagy.
    BMC complementary and alternative medicine, 2017, Sep-26, Volume: 17, Issue:1

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Autophagy; Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Ethanol; Female; Humans; Phenylethyl Alcohol; Propolis; Signal Transduction; Toll-Like Receptor 4; Tumor Microenvironment

2017
Apoptosis induced by caffeic acid phenethyl ester in human oral cancer cell lines: Involvement of Puma and Bax activation.
    Archives of oral biology, 2017, Volume: 84

    Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Biomarkers, Tumor; Blotting, Western; Caffeic Acids; Cell Line, Tumor; Cell Transformation, Neoplastic; Humans; Immunohistochemistry; Mouth Neoplasms; Phenylethyl Alcohol; Proto-Oncogene Proteins; Staining and Labeling

2017
Migration Rate Inhibition of Breast Cancer Cells Treated by Caffeic Acid and Caffeic Acid Phenethyl Ester: An In Vitro Comparison Study.
    Nutrients, 2017, Oct-19, Volume: 9, Issue:10

    Topics: Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Female; Humans; Mitochondria; Phenylethyl Alcohol; Propolis

2017
Antifilarial activity of caffeic acid phenethyl ester on Brugia pahangi in vitro and in vivo.
    Pathogens and global health, 2017, Volume: 111, Issue:7

    Topics: Animals; Brugia pahangi; Caffeic Acids; Dose-Response Relationship, Drug; Filariasis; Gerbillinae; Humans; Male; Phenylethyl Alcohol; Wolbachia

2017
Structure, antioxidative potency and potential scavenging of OH and OOH of phenylethyl-3,4-dihydroxyhydrocinnamate in protic and aprotic media: DFT study.
    Journal of molecular graphics & modelling, 2017, Volume: 78

    Topics: Antioxidants; Caffeic Acids; Hydrogen; Hydroxides; Hydroxyl Radical; Oxidation-Reduction; Phenylethyl Alcohol; Solvents; Thermodynamics; Water

2017
Marker-based standardization and investigation of nutraceutical potential of Indian propolis.
    Journal of integrative medicine, 2017, Volume: 15, Issue:6

    Topics: Animals; Antioxidants; Bees; Caffeic Acids; Chromatography, High Pressure Liquid; Dietary Supplements; Ethanol; Flavanones; Flavonoids; Humans; India; Nutritive Value; Phenylethyl Alcohol; Plant Extracts; Polyphenols; Propolis

2017
Caffeic acid phenethyl ester promotes haematopoietic stem/progenitor cell homing and engraftment.
    Stem cell research & therapy, 2017, Nov-07, Volume: 8, Issue:1

    Topics: Animals; Caffeic Acids; Cells, Cultured; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred C57BL; Phenylethyl Alcohol; Stem Cells

2017
Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Cytokines; Dose-Response Relationship, Drug; Drug Discovery; Humans; Inflammation; Lipopolysaccharides; Lymphocyte Antigen 96; Macrophages; Mice; Mice, Inbred C57BL; Molecular Structure; Phenylethyl Alcohol; Structure-Activity Relationship

2018
Caffeic Acid Phenethyl Ester (CAPE) Protects PC12 Cells from Cisplatin-Induced Neurotoxicity by Activating the NGF-Signaling Pathway.
    Neurotoxicity research, 2018, Volume: 34, Issue:1

    Topics: Analysis of Variance; Animals; Caffeic Acids; Cell Differentiation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibitors; GAP-43 Protein; Nerve Growth Factor; Neuroblastoma; Neurofilament Proteins; Neuronal Outgrowth; Neuroprotective Agents; Neurotoxins; PC12 Cells; Phenylethyl Alcohol; Rats; Signal Transduction; Synapsins; Synaptophysin

2018
Antioxidant activity of CAPE (caffeic acid phenethyl ester) in vitro can protect human sperm deoxyribonucleic acid from oxidative damage.
    Acta histochemica, 2018, Volume: 120, Issue:2

    Topics: Antioxidants; Caffeic Acids; Humans; Male; Microscopy, Electron, Transmission; Oxidative Stress; Phenylethyl Alcohol; Semen Analysis; Spermatozoa

2018
Anticancer Activity in Honeybee Propolis: Functional Insights to the Role of Caffeic Acid Phenethyl Ester and Its Complex With γ-Cyclodextrin.
    Integrative cancer therapies, 2018, Volume: 17, Issue:3

    Topics: A549 Cells; Animals; Antineoplastic Agents; Apitherapy; Caffeic Acids; Drug Combinations; Female; gamma-Cyclodextrins; HeLa Cells; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Phenylethyl Alcohol; Propolis; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2018
Aspergillus niger whole-cell catalyzed synthesis of caffeic acid phenethyl ester in ionic liquids.
    Enzyme and microbial technology, 2018, Volume: 111

    Topics: Alcohols; Aspergillus niger; Biocatalysis; Bioreactors; Caffeic Acids; Esterification; Fungal Proteins; Ionic Liquids; Kinetics; Lipase; Phenylethyl Alcohol; Solubility; Temperature

2018
Chlorpyrifos-induced parkinsonian model in mice: Behavior, histopathology and biochemistry.
    Pesticide biochemistry and physiology, 2018, Volume: 144

    Topics: Animals; Antioxidants; Aryldialkylphosphatase; Brain; Caffeic Acids; Chlorpyrifos; Disease Models, Animal; Insecticides; Lipid Metabolism; Male; Mice; Motor Activity; N-Acetylneuraminic Acid; Neuroprotective Agents; Parkinsonian Disorders; Phenylethyl Alcohol

2018
Caffeic acid phenethyl ester rescued streptozotocin-induced memory loss through PI3-kinase dependent pathway.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 101

    Topics: Animals; Caffeic Acids; Female; Male; Maze Learning; Memory Disorders; Oxidative Stress; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Rats; Rats, Wistar; Signal Transduction; Streptozocin

2018
Caffeic acid phenethyl ester synergistically enhances the antifungal activity of fluconazole against resistant Candida albicans.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Feb-01, Volume: 40

    Topics: Animals; Antifungal Agents; Caenorhabditis elegans; Caffeic Acids; Candida albicans; Candidiasis; Disease Models, Animal; Drug Resistance, Fungal; Drug Synergism; Drug Therapy, Combination; Fluconazole; Microbial Sensitivity Tests; Phenylethyl Alcohol

2018
Caffeic Acid Phenethyl Ester Improves Metabolic Syndrome by Activating PPAR-γ and Inducing Adipose Tissue Remodeling in Diet-Induced Obese Mice.
    Molecular nutrition & food research, 2018, Volume: 62, Issue:10

    Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Body Weight; Caffeic Acids; Diet, High-Fat; Hyperlipidemias; Insulin Resistance; Male; Metabolic Syndrome; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Organ Size; Panniculitis; Phenylethyl Alcohol; PPAR gamma

2018
Attenuating effects of caffeic acid phenethyl ester and betaine on abamectin-induced hepatotoxicity and nephrotoxicity.
    Environmental science and pollution research international, 2018, Volume: 25, Issue:16

    Topics: Animals; Antioxidants; Betaine; Caffeic Acids; Catalase; Chemical and Drug Induced Liver Injury; Creatinine; Glutathione; Glutathione Peroxidase; Ivermectin; Kidney; Male; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase

2018
Caffeic acid phenethyl ester down-regulates claudin-2 expression at the transcriptional and post-translational levels and enhances chemosensitivity to doxorubicin in lung adenocarcinoma A549 cells.
    The Journal of nutritional biochemistry, 2018, Volume: 56

    Topics: A549 Cells; Adenocarcinoma of Lung; Caffeic Acids; Cantharidin; Cell Line, Tumor; Cell Proliferation; Chloroquine; Claudins; Down-Regulation; Doxorubicin; Drug Synergism; Fatty Acids; Gene Expression Regulation; Humans; Lung Neoplasms; Lysosomes; Permeability; Phenylethyl Alcohol; Promoter Regions, Genetic; Propolis; RNA, Messenger; Tight Junctions

2018
Caffeic acid phenethyl ester guards against benign prostate hypertrophy in rats: Role of IGF-1R/protein kinase-B (Akt)/β-catenin signaling.
    IUBMB life, 2018, Volume: 70, Issue:6

    Topics: Animals; beta Catenin; Caffeic Acids; Gene Expression Regulation, Neoplastic; Male; Phenylethyl Alcohol; Prostatic Hyperplasia; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1

2018
Synergistic effect of caffeic acid phenethyl ester with caspofungin against Candida albicans is mediated by disrupting iron homeostasis.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 116, Issue:Pt B

    Topics: Antifungal Agents; Caffeic Acids; Candida albicans; Caspofungin; Drug Synergism; Echinocandins; Homeostasis; Iron; Lipopeptides; Microbial Sensitivity Tests; Mitochondria; Phenylethyl Alcohol; Reactive Oxygen Species

2018
Caffeic acid phenethyl ester inhibits the progression of ovarian cancer by regulating NF-?B signaling.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: Animals; Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Survival; Disease Progression; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Ovarian Neoplasms; Phenylethyl Alcohol; Phosphorylation; Signal Transduction; Transcription Factor RelA; Xenograft Model Antitumor Assays

2018
Caffeic Acid Phenethyl Ester Induces
    International journal of molecular sciences, 2018, May-08, Volume: 19, Issue:5

    Topics: Apoptosis; Caffeic Acids; Carcinoma; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Intracellular Signaling Peptides and Proteins; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Phenylethyl Alcohol; Phosphorylation; Signal Transduction; STAT3 Transcription Factor

2018
Antibacterial and antioxidant electrospun materials from poly(3-hydroxybutyrate) and polyvinylpyrrolidone containing caffeic acid phenethyl ester - "in" and "on" strategies for enhanced solubility.
    International journal of pharmaceutics, 2018, Jul-10, Volume: 545, Issue:1-2

    Topics: Anti-Bacterial Agents; Antioxidants; Biphenyl Compounds; Caffeic Acids; Calorimetry, Differential Scanning; Crystallography, X-Ray; Dosage Forms; Drug Compounding; Escherichia coli; Hydroxybutyrates; Microscopy, Electron, Scanning; Phenylethyl Alcohol; Picrates; Polyesters; Povidone; Solubility; Spectroscopy, Fourier Transform Infrared; Staphylococcus aureus; Technology, Pharmaceutical

2018
Anti-glioma Effects of Caffeic Acid Phenethyl Ester and Dasatinib Combination Therapy in an in vivo Rat Glioma Model.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:12

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Proliferation; Dasatinib; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Glioma; Male; Molecular Structure; Phenylethyl Alcohol; Rats; Rats, Wistar; Structure-Activity Relationship; Tumor Cells, Cultured

2018
Caffeic acid phenethyl ester promotes wound healing of mice pressure ulcers affecting NF-κB, NOS2 and NRF2 expression.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Caffeic Acids; Disease Models, Animal; Gene Expression Regulation; Inflammation; Lipid Peroxidation; Male; Mice; NF-E2-Related Factor 2; NF-kappa B p50 Subunit; Nitric Oxide Synthase Type II; Oxidative Stress; Phenylethyl Alcohol; Pressure Ulcer; Reactive Oxygen Species; Reperfusion Injury; Skin; Wound Healing

2018
Caffeic acid phenethyl ester (CAPE) possesses pro-hypoxia and anti-stress activities: bioinformatics and experimental evidences.
    Cell stress & chaperones, 2018, Volume: 23, Issue:5

    Topics: Caffeic Acids; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Computational Biology; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mixed Function Oxygenases; Molecular Docking Simulation; Phenylethyl Alcohol; Protein Aggregates; Stress, Physiological

2018
Effects of caffeic acid phenethyl ester application on dentin MMP-2, stability of bond strength and failure mode of total-etch and self-etch adhesive systems.
    Archives of oral biology, 2018, Volume: 94

    Topics: Acid Etching, Dental; Analysis of Variance; Caffeic Acids; Composite Resins; Dental Bonding; Dental Cements; Dental Restoration Failure; Dentin; Dentin-Bonding Agents; Glass Ionomer Cements; Humans; In Vitro Techniques; Materials Testing; Matrix Metalloproteinase 2; Microscopy, Electron, Scanning; Molar, Third; Phenylethyl Alcohol; Resin Cements; Stress, Mechanical; Surface Properties; Tensile Strength

2018
Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI.
    Journal of neuroscience research, 2018, Volume: 96, Issue:12

    Topics: Amino Acid Oxidoreductases; AMP-Activated Protein Kinases; Animals; Antioxidants; Behavior Rating Scale; Brain Injuries, Traumatic; Caffeic Acids; Disease Models, Animal; Drug Synergism; Dynamins; GTP Phosphohydrolases; Heme Oxygenase-1; Membrane Proteins; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Neurons; Neuroprotective Agents; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenylethyl Alcohol; Protein Serine-Threonine Kinases; S-Nitrosoglutathione; Superoxide Dismutase

2018
Inhibition of nuclear factor-κB p65 phosphorylation by 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester.
    Journal of pharmacological sciences, 2018, Volume: 137, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Nucleus; Depression, Chemical; Inflammation; Interleukin-1beta; Mice; NF-kappa B; Nitric Oxide Synthase; Nitrites; Phenylethyl Alcohol; Phosphorylation; RAW 264.7 Cells; Signal Transduction

2018
Development of a biodegradable antifibrotic local drug delivery system for glaucoma microstents.
    Bioscience reports, 2018, 08-31, Volume: 38, Issue:4

    Topics: Animals; Caffeic Acids; Drug Delivery Systems; Drug-Eluting Stents; Fibrosis; Glaucoma; Male; Paclitaxel; Phenylethyl Alcohol; Pyridones; Rats; Rats, Wistar

2018
Caffeic acid phenethyl ester (CAPE) reverses fibrosis caused by chronic colon inflammation in murine model of colitis.
    Pathology, research and practice, 2018, Volume: 214, Issue:11

    Topics: Animals; Caffeic Acids; Colitis; Colon; Disease Models, Animal; Female; Fibrosis; Inflammation; Mice; Mice, Inbred C57BL; Phenylethyl Alcohol

2018
Effects of Intrathecal Caffeic Acid Phenethyl Ester (CAPE) on IL-6 and TNF-α Levels and Local Inflammatory Responses in Spinal Cord Injuries.
    Turkish neurosurgery, 2018, Volume: 28, Issue:4

    Topics: Animals; Caffeic Acids; Edema; Female; Hemorrhage; Injections, Spinal; Interleukin-6; Methylprednisolone; Phenylethyl Alcohol; Rats; Spinal Cord; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2018
Caffeic Acid Versus Caffeic Acid Phenethyl Ester in the Treatment of Breast Cancer MCF-7 Cells: Migration Rate Inhibition.
    Integrative cancer therapies, 2018, Volume: 17, Issue:4

    Topics: Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; MCF-7 Cells; Phenylethyl Alcohol

2018
Albumin nano-encapsulation of caffeic acid phenethyl ester and piceatannol potentiated its ability to modulate HIF and NF-kB pathways and improves therapeutic outcome in experimental colitis.
    Drug delivery and translational research, 2019, Volume: 9, Issue:1

    Topics: Albumins; Animals; Biological Availability; Caffeic Acids; Colitis; Dextran Sulfate; Disease Models, Animal; Drug Combinations; Drug Compounding; Drug Synergism; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Nanoparticles; Particle Size; Phenylethyl Alcohol; Signal Transduction; Stilbenes; Transcription Factor RelA

2019
Caffeic acid phenethyl ester exerts apoptotic and oxidative stress on human multiple myeloma cells.
    Investigational new drugs, 2019, Volume: 37, Issue:5

    Topics: Antioxidants; Apoptosis; Biomarkers, Tumor; Caffeic Acids; Cell Movement; Cell Proliferation; Gene Expression Profiling; Humans; Multiple Myeloma; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species; Tumor Cells, Cultured

2019
Caffeic acid phenethyl ester potentiates gastric cancer cell sensitivity to doxorubicin and cisplatin by decreasing proteasome function.
    Anti-cancer drugs, 2019, Volume: 30, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caffeic Acids; Cell Proliferation; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Drug Therapy, Combination; Humans; Phenylethyl Alcohol; Proteasome Endopeptidase Complex; Stomach Neoplasms; Tumor Cells, Cultured

2019
Evaluation of PECAM-1 and p38 MAPK expressions in cerebellum tissue of rats treated with caffeic acid phenethyl ester: a biochemical and immunohistochemical study.
    Folia morphologica, 2019, Volume: 78, Issue:2

    Topics: Animals; Caffeic Acids; Catalase; Cerebellum; Glutathione Peroxidase; Immunohistochemistry; Male; Malondialdehyde; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Platelet Endothelial Cell Adhesion Molecule-1; Rats, Sprague-Dawley; Superoxide Dismutase

2019
Synthesis of Diverse Hydroxycinnamoyl Phenylethanoid Esters Using Escherichia coli.
    Journal of agricultural and food chemistry, 2019, Feb-20, Volume: 67, Issue:7

    Topics: Caffeic Acids; Coumaric Acids; Escherichia coli; Esterification; Esters; Glucose; Mannosyltransferases; Oryza; Phenylethyl Alcohol; Transformation, Bacterial

2019
Repurposing nitrocatechols: 5-Nitro-α-cyanocarboxamide derivatives of caffeic acid and caffeic acid phenethyl ester effectively inhibit aggregation of tau-derived hexapeptide AcPHF6.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Caffeic Acids; Catechols; Chelating Agents; Copper; Drug Design; Nitro Compounds; Peptides; Phenylethyl Alcohol; Polyphenols; Protein Aggregation, Pathological; Small Molecule Libraries; tau Proteins; Tauopathies

2019
Caffeic acid phenethyl ester protects against oxidative stress and dampens inflammation via heme oxygenase 1.
    International journal of oral science, 2019, 02-20, Volume: 11, Issue:1

    Topics: Animals; Caffeic Acids; Heme Oxygenase-1; Humans; Inflammation; Mice; NF-kappa B; Oxidative Stress; Phenylethyl Alcohol

2019
Protective effects of caffeic acid phenethyl ester and thymoquinone on toluene induced liver toxicity.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2019, Volume: 94, Issue:4

    Topics: Animals; Benzoquinones; Caffeic Acids; Chemical and Drug Induced Liver Injury; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Toluene

2019
Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties.
    Bioorganic chemistry, 2019, Volume: 86

    Topics: Animals; Biphenyl Compounds; Caffeic Acids; Cattle; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Models, Molecular; Molecular Structure; Phenylethyl Alcohol; Picrates; Reactive Oxygen Species; Structure-Activity Relationship; Xanthine Oxidase

2019
Inhibitory Effect of CAPE and Kaempferol in Colon Cancer Cell Lines-Possible Implications in New Therapeutic Strategies.
    International journal of molecular sciences, 2019, Mar-09, Volume: 20, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Proliferation; Cell Survival; Colonic Neoplasms; HCT116 Cells; Humans; Kaempferols; Neoplasm Invasiveness; Phenylethyl Alcohol

2019
Caffeic Acid Phenethyl Ester Rescues Pulmonary Arterial Hypertension through the Inhibition of AKT/ERK-Dependent PDGF/HIF-1α In Vitro and In Vivo.
    International journal of molecular sciences, 2019, Mar-22, Volume: 20, Issue:6

    Topics: Animals; Apoptosis; Caffeic Acids; Cell Line; Cell Proliferation; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Phenylethyl Alcohol; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Rats; Signal Transduction; Vascular Remodeling

2019
Transglycosylation Improved Caffeic Acid Phenethyl Ester Anti-Inflammatory Activity and Water Solubility by Leuconostoc mesenteroides Dextransucrase.
    Journal of agricultural and food chemistry, 2019, Apr-24, Volume: 67, Issue:16

    Topics: Animals; Anti-Inflammatory Agents; Bacterial Proteins; Biocatalysis; Caffeic Acids; Glucosyltransferases; Interleukin-6; Leuconostoc mesenteroides; Macrophages; Mice; Molecular Structure; Phenylethyl Alcohol; RAW 264.7 Cells; Solubility; Tumor Necrosis Factor-alpha

2019
Cardioprotective effect of caffeic acid phenethyl ester on cardiac contusion following blunt chest trauma in rats.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2019, Volume: 94, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Caffeic Acids; Heart; Male; Myocardial Contusions; Myocardium; Phenylethyl Alcohol; Rats, Wistar; Thoracic Injuries; Wounds, Nonpenetrating

2019
Effects of caffeic acid phenethyl ester (CAPE) on angiogenesis, apoptosis and oxidatıve stress ın various cancer cell lines.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2019, Volume: 94, Issue:7

    Topics: Angiogenesis Inducing Agents; Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Neovascularization, Pathologic; Oxidative Stress; Phenylethyl Alcohol; Propolis

2019
Caffeic Acid Phenethyl Ester (CAPE) Protects PC12 Cells Against Cisplatin-Induced Neurotoxicity by Activating the AMPK/SIRT1, MAPK/Erk, and PI3k/Akt Signaling Pathways.
    Neurotoxicity research, 2019, Volume: 36, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Caffeic Acids; Cell Differentiation; Chlorocebus aethiops; Cisplatin; COS Cells; Cytoskeletal Proteins; Glucose; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; PC12 Cells; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; Sirtuin 1

2019
Caffeic acid phenethyl ester attenuates nuclear factor‑κB‑mediated inflammatory responses in Müller cells and protects against retinal ganglion cell death.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: Animals; Astrocytes; Caffeic Acids; Cell Death; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Survival; Chemokine CCL2; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Ependymoglial Cells; Glaucoma; Gliosis; In Situ Nick-End Labeling; Inflammation; Interleukin-6; Interleukin-8; Lipopolysaccharides; Male; NF-kappa B; Nitric Oxide Synthase Type II; Optic Nerve Injuries; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Signal Transduction; Transcription Factor Brn-3A; Tumor Necrosis Factor-alpha

2019
Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats.
    International journal of molecular sciences, 2019, May-17, Volume: 20, Issue:10

    Topics: Amidohydrolases; Animals; Antioxidants; Caffeic Acids; Diabetes Mellitus, Experimental; Glutamate-Cysteine Ligase; Heme Oxygenase (Decyclizing); Male; Nitric Oxide Synthase Type II; Phenylethyl Alcohol; Propolis; Rats; Rats, Wistar; Streptozocin; Up-Regulation

2019
Caffeic acid phenethyl ester suppressed growth and metastasis of nasopharyngeal carcinoma cells by inactivating the NF-κB pathway.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; NF-kappa B; Phenylethyl Alcohol; Structure-Activity Relationship; Tumor Cells, Cultured; Wound Healing

2019
Caffeic Acid Phenethyl Ester Inhibits UV-Induced MMP-1 Expression by Targeting Histone Acetyltransferases in Human Skin.
    International journal of molecular sciences, 2019, Jun-22, Volume: 20, Issue:12

    Topics: Caffeic Acids; Fibroblasts; Gene Expression Regulation; Histone Acetyltransferases; Humans; Matrix Metalloproteinase 1; Phenylethyl Alcohol; Skin; Ultraviolet Rays

2019
Caffeic Acid Esters Are Effective Bactericidal Compounds Against
    Biomolecules, 2019, 07-27, Volume: 9, Issue:8

    Topics: Anti-Bacterial Agents; Caffeic Acids; Glutathione; Microbial Sensitivity Tests; Paenibacillus larvae; Phenylethyl Alcohol; Plant Extracts; Propolis; Reactive Oxygen Species

2019
Caffeic Acid Phenethyl Ester Inhibits the Proliferation of HEp2 Cells by Regulating Stat3/Plk1 Pathway and Inducing S Phase Arrest.
    Biological & pharmaceutical bulletin, 2019, Oct-01, Volume: 42, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Caffeic Acids; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Humans; Laryngeal Neoplasms; Phenylethyl Alcohol; Polo-Like Kinase 1; Polyphenols; Propolis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; S Phase; STAT3 Transcription Factor

2019
Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213.
    Cell communication and signaling : CCS, 2019, 08-20, Volume: 17, Issue:1

    Topics: Caffeic Acids; Dose-Response Relationship, Drug; Humans; Phenylethyl Alcohol; Phosphorylation; Receptors, Androgen; Serine; Signal Transduction; Structure-Activity Relationship; Tumor Cells, Cultured

2019
Caffeic acid phenethyl ester ameliorates pulmonary inflammation and apoptosis reducing Nf-κβ activation in blunt pulmonary contusion model.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2019, Volume: 25, Issue:5

    Topics: Animals; Apoptosis; Caffeic Acids; Lung Injury; NF-kappa B; Phenylethyl Alcohol; Pneumonia; Rats; Rats, Wistar

2019
Depolarization of pacemaker potentials by caffeic acid phenethyl ester in interstitial cells of Cajal from the murine small intestine.
    Canadian journal of physiology and pharmacology, 2020, Volume: 98, Issue:4

    Topics: Animals; Caffeic Acids; Calcium; Gastrointestinal Motility; Interstitial Cells of Cajal; Intestine, Small; Membrane Potentials; Mice; Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Phenylethyl Alcohol; Protein Kinase Inhibitors; Thapsigargin

2020
An evaluation of the effects of caffeic acid phenethyl ester and Ankaferd blood stopper on secondary wound healing of oral mucosal tissue
    Turkish journal of medical sciences, 2020, 02-13, Volume: 50, Issue:1

    Topics: Animals; Caffeic Acids; Drug Administration Schedule; Gene Expression; Male; Mouth Mucosa; Phenylethyl Alcohol; Plant Extracts; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Wound Healing

2020
Caffeic acid phenethyl ester attenuates changes in pancreatic tissue damage biomarkers induced by cisplatin.
    Canadian journal of physiology and pharmacology, 2020, Volume: 98, Issue:5

    Topics: Animals; Biomarkers; Caffeic Acids; Cisplatin; Cytoprotection; Male; Necrosis; Pancreas; Phenylethyl Alcohol; Rats; Rats, Wistar

2020
FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Protects against Oxidative Stress-Mediated Neuronal Cell Apoptosis and Scopolamine-Induced Cognitive Impairment by Activating Nrf2/HO-1 Signaling.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Alzheimer Disease; Animals; Apoptosis; Caffeic Acids; Cognitive Dysfunction; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Humans; Male; Mice; Mice, Inbred Strains; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; PC12 Cells; Phenylethyl Alcohol; Rats; RNA, Small Interfering; Scopolamine; Signal Transduction

2019
Investigation of the preventive effects of dehydroepiandrosterone (DHEA) and Caffeic acid phenethyl ester (CAPE) on cisplatin-induced ovarian damage in rats.
    Ultrastructural pathology, 2020, Jan-02, Volume: 44, Issue:1

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cisplatin; Dehydroepiandrosterone; Female; Ovarian Reserve; Ovary; Phenylethyl Alcohol; Rats; Rats, Wistar

2020
Caffeic Acid Phenethyl Ester (CAPE) Induces VEGF Expression and Production in Rat Odontoblastic Cells.
    BioMed research international, 2019, Volume: 2019

    Topics: Animals; Apoptosis; Caffeic Acids; Cell Line; Dental Caries; Dental Pulp Calcification; I-kappa B Proteins; Inflammation; NF-kappa B; Odontoblasts; Phenylethyl Alcohol; Propolis; Rats; Transcriptional Activation; Vascular Endothelial Growth Factor A

2019
Enhanced antibacterial and antiparasitic activity of multifunctional polymeric nanoparticles.
    Nanotechnology, 2020, Apr-24, Volume: 31, Issue:17

    Topics: Anti-Bacterial Agents; Antiparasitic Agents; Caffeic Acids; Escherichia coli; Leishmania; Microbial Sensitivity Tests; Nanoparticles; Naphthoquinones; Particle Size; Phenylethyl Alcohol; Polylactic Acid-Polyglycolic Acid Copolymer; Staphylococcus aureus

2020
FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Ameliorates DSS-Induced Colitis Against Oxidative Stress by Activating Nrf2/HO-1 Pathway.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Animals; Antioxidants; Caffeic Acids; Cells, Cultured; Colitis; Dextran Sulfate; Female; Heme Oxygenase-1; Inflammatory Bowel Diseases; Membrane Proteins; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol; RAW 264.7 Cells; Signal Transduction

2019
A biochemical and immunohistochemical study of the effects of caffeic acid phenethyl ester on alveolar bone loss and oxidative stress in diabetic rats with experimental periodontitis.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2020, Volume: 95, Issue:6

    Topics: Alveolar Bone Loss; Animals; Caffeic Acids; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Oxidative Stress; Periodontitis; Phenylethyl Alcohol; Rats, Wistar; Streptozocin

2020
Antagonistic Effects of CAPE (a Component of Propolis) on the Cytotoxicity and Genotoxicity of Irinotecan and SN38 in Human Gastrointestinal Cancer Cells In Vitro.
    Molecules (Basel, Switzerland), 2020, Feb-04, Volume: 25, Issue:3

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cytotoxins; DNA Damage; Drug Synergism; HCT116 Cells; HT29 Cells; Humans; Hydrogen Peroxide; Irinotecan; Lymphocytes; Mutagens; Oxidative Stress; Phenylethyl Alcohol; Propolis; Topoisomerase I Inhibitors

2020
A caffeic acid phenethyl ester analog inhibits the proliferation of nasopharyngeal carcinoma cells via targeting epidermal growth factor receptor.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; ErbB Receptors; Fibroblasts; Gene Expression; HeLa Cells; Humans; MCF-7 Cells; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Phenylethyl Alcohol; Signal Transduction

2020
The Impact of Propolis Factor Caffeic Acid Phenethyl-Ester on the Cerebral Vasospasm and Early Brain Damage in the Experimentally Induced Subarachnoid Hemorrhage on Rats.
    World neurosurgery, 2020, Volume: 138

    Topics: Animals; CA3 Region, Hippocampal; Caffeic Acids; Disease Models, Animal; Neurons; Neuroprotective Agents; Phenylethyl Alcohol; Propolis; Rats, Wistar; Subarachnoid Hemorrhage; Vasospasm, Intracranial

2020
Protective effect of caffeic acid phenethyl ester against imidacloprid-induced hepatotoxicity by attenuating oxidative stress, endoplasmic reticulum stress, inflammation and apoptosis.
    Pesticide biochemistry and physiology, 2020, Volume: 164

    Topics: Animals; Antioxidants; Apoptosis; Caffeic Acids; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum Stress; Humans; Inflammation; Mice; Neonicotinoids; Nitro Compounds; Oxidative Stress; Phenylethyl Alcohol

2020
Inhibiting the NF-κB pathway enhances the antitumor effect of cabazitaxel by downregulating Bcl-2 in pancreatic cancer.
    International journal of oncology, 2020, Volume: 57, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; NF-kappa B; Pancreatic Neoplasms; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Taxoids; Xenograft Model Antitumor Assays

2020
Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (M
    Journal of biomolecular structure & dynamics, 2021, Volume: 39, Issue:11

    Topics: Caffeic Acids; COVID-19; Humans; Molecular Docking Simulation; Peptide Hydrolases; Phenylethyl Alcohol; Protease Inhibitors; SARS-CoV-2; Withanolides

2021
Long-term Evaluation of Dentin Matrix Stability and Gelatinolytic Activity after Dentin Pretreatment with Caffeic Acid Phenethyl Ester.
    The journal of adhesive dentistry, 2020, Volume: 22, Issue:3

    Topics: Caffeic Acids; Dental Bonding; Dental Cements; Dentin; Dentin-Bonding Agents; Materials Testing; Phenylethyl Alcohol; Tensile Strength

2020
Integrated Analysis of mRNA-seq and miRNA-seq to Identify c-MYC, YAP1 and miR-3960 as Major Players in the Anticancer Effects of Caffeic Acid Phenethyl Ester in Human Small Cell Lung Cancer Cell Line.
    Current gene therapy, 2020, Volume: 20, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Phenylethyl Alcohol; Proto-Oncogene Proteins c-myc; RNA-Seq; Small Cell Lung Carcinoma; Transcription Factors; YAP-Signaling Proteins

2020
Antibacterial Effect of Caffeic Acid Phenethyl Ester on Cariogenic Bacteria and Streptococcus mutans Biofilms.
    Antimicrobial agents and chemotherapy, 2020, 08-20, Volume: 64, Issue:9

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Caffeic Acids; Dental Caries; Humans; Phenylethyl Alcohol; Streptococcus mutans

2020
Research on the protective effect of caffeic acid phenethyl ester on testicular damage caused by cisplatin
    Turkish journal of medical sciences, 2020, 12-17, Volume: 50, Issue:8

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cisplatin; Disease Models, Animal; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Testicular Diseases; Testis

2020
Evaluation of the neuroprotective potential of caffeic acid phenethyl ester in a cellular model of Parkinson's disease.
    European journal of pharmacology, 2020, Sep-15, Volume: 883

    Topics: Antiparkinson Agents; Apoptosis; Apoptosis Regulatory Proteins; Caffeic Acids; Cell Line, Tumor; Humans; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease; Phenylethyl Alcohol; Reactive Oxygen Species; Signal Transduction

2020
Caffeic Acid Phenethyl Ester (CAPE) Induced Apoptosis in Serous Ovarian Cancer OV7 Cells by Deregulation of BCL2/BAX Genes.
    Molecules (Basel, Switzerland), 2020, Jul-31, Volume: 25, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Autophagosomes; bcl-2-Associated X Protein; Caffeic Acids; Cell Line, Tumor; Cell Survival; Female; Gene Expression; Humans; Ovarian Neoplasms; Phenylethyl Alcohol; Proto-Oncogene Proteins c-bcl-2

2020
Mechanism of synergistic DNA damage induced by caffeic acid phenethyl ester (CAPE) and Cu(II): Competitive binding between CAPE and DNA with Cu(II)/Cu(I).
    Free radical biology & medicine, 2020, 11-01, Volume: 159

    Topics: Animals; Binding, Competitive; Caffeic Acids; Copper; DNA; DNA Damage; Hydrogen Peroxide; Phenylethyl Alcohol

2020
Caffeic acid phenethyl ester, a coffee polyphenol, inhibits DNA methylation in vitro and in vivo.
    European journal of pharmacology, 2020, Nov-15, Volume: 887

    Topics: Animals; Caffeic Acids; Coffee; DNA Methylation; Dose-Response Relationship, Drug; Epigenesis, Genetic; Female; HT29 Cells; Humans; Male; Mice; Mice, Transgenic; Molecular Docking Simulation; Phenylethyl Alcohol; Polyphenols; Pregnancy; Prenatal Exposure Delayed Effects; Protein Structure, Secondary; Salmon

2020
The investigation of antioxidant and anti-inflammatory potentials of apitherapeutic agents on heart tissues in nitric oxide synthase inhibited rats via Nω-nitro-L-arginine methyl ester.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2021, Jan-02, Volume: 43, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Aryldialkylphosphatase; Blood Pressure; Caffeic Acids; Free Radical Scavengers; Male; Myocardium; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Pollen; Propolis; Rats; Rats, Sprague-Dawley

2021
Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain in Sprague-Dawley rats: Emphasis on the modulation of oxidative stress and neuroinflammation.
    Neuropharmacology, 2020, 12-15, Volume: 181

    Topics: Animals; Antibiotics, Antineoplastic; Avoidance Learning; Brain Chemistry; Caffeic Acids; Caspase 3; Chemotherapy-Related Cognitive Impairment; Doxorubicin; Encephalitis; Glial Fibrillary Acidic Protein; Hippocampus; Inflammation Mediators; Male; Maze Learning; Memory; Motor Activity; Neuroprotective Agents; Oxidative Stress; Phenylethyl Alcohol; Prefrontal Cortex; Rats; Rats, Sprague-Dawley

2020
Caffeic Acid Phenethyl Ester Loaded in Skim Milk Microcapsules: Physicochemical Properties and Enhanced
    Journal of agricultural and food chemistry, 2020, Dec-16, Volume: 68, Issue:50

    Topics: Animals; Biological Availability; Caffeic Acids; Cattle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Drug Compounding; Milk; Phenylethyl Alcohol

2020
Antimyeloma Potential of Caffeic Acid Phenethyl Ester and Its Analogues through Sp1 Mediated Downregulation of IKZF1-IRF4-MYC Axis.
    Journal of natural products, 2020, 12-24, Volume: 83, Issue:12

    Topics: Angiogenesis Inhibitors; Apoptosis; Caffeic Acids; Cell Line, Tumor; Down-Regulation; Genes, myc; Humans; Ikaros Transcription Factor; Interferon Regulatory Factors; Lenalidomide; Multiple Myeloma; Phenylethyl Alcohol; Sp1 Transcription Factor; Structure-Activity Relationship

2020
The effect of caffeic acid phenethyl ester and Ankaferd Blood Stopper on the diabetic and nondiabetic gingival wound healing: an experimental study
    Turkish journal of medical sciences, 2021, 04-30, Volume: 51, Issue:2

    Topics: Animals; Caffeic Acids; Diabetes Mellitus; Male; Mouth Mucosa; Phenylethyl Alcohol; Plant Extracts; Rats; Rats, Wistar; Wound Healing

2021
Propolis Suppresses UV-Induced Photoaging in Human Skin through Directly Targeting Phosphoinositide 3-Kinase.
    Nutrients, 2020, Dec-10, Volume: 12, Issue:12

    Topics: Apigenin; Caffeic Acids; Collagen; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Plant Extracts; Propolis; Quercetin; Skin; Skin Aging; Ultraviolet Rays

2020
Synergic antioxidant activity of γ-terpinene with phenols and polyphenols enabled by hydroperoxyl radicals.
    Food chemistry, 2021, May-30, Volume: 345

    Topics: Antioxidants; Caffeic Acids; Chromans; Cyclohexane Monoterpenes; Drug Synergism; Peroxides; Phenols; Phenylethyl Alcohol; Polyphenols

2021
Discovery of CAPE derivatives as dual EGFR and CSK inhibitors with anticancer activity in a murine model of hepatocellular carcinoma.
    Bioorganic chemistry, 2021, Volume: 107

    Topics: Animals; Antineoplastic Agents; Binding Sites; Caffeic Acids; Carcinoma, Hepatocellular; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Liver Neoplasms; Male; Mice; Molecular Docking Simulation; Phenylethyl Alcohol; src-Family Kinases; Structure-Activity Relationship

2021
Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives.
    Biomolecules, 2020, 12-29, Volume: 11, Issue:1

    Topics: Caffeic Acids; Cathepsin B; Cathepsin L; Chlorogenic Acid; Drug Discovery; Enzyme Inhibitors; Humans; Phenylethyl Alcohol; Proteolysis

2020
Formulation Development of Folic Acid Conjugated PLGA Nanoparticles for Improved Cytotoxicity of Caffeic Acid Phenethyl Ester.
    Pharmaceutical nanotechnology, 2021, Volume: 9, Issue:2

    Topics: Caffeic Acids; Folic Acid; Nanoparticles; Phenylethyl Alcohol

2021
Effects of Caffeic Acid Phenethyl Ester and Oxidative Stress Caused by the Exhaustion Exercise on Endotelial Damage.
    Archives italiennes de biologie, 2020, Jun-30, Volume: 158, Issue:2

    Topics: Animals; Antioxidants; Caffeic Acids; Endothelium; Inflammation; Male; Oxidative Stress; Phenylethyl Alcohol; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley

2020
Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers.
    Biomolecules, 2021, 01-26, Volume: 11, Issue:2

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Caffeic Acids; Computational Biology; Computer Simulation; Dimerization; ErbB Receptors; Erlotinib Hydrochloride; Exons; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Indolizines; Ligands; Lung Neoplasms; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Phenylethyl Alcohol; Quinazolines; Withanolides

2021
Interaction between caffeic acid/caffeic acid phenethyl ester and micellar casein.
    Food chemistry, 2021, Jul-01, Volume: 349

    Topics: Antioxidants; Caffeic Acids; Caseins; Hydrophobic and Hydrophilic Interactions; Micelles; Phenylethyl Alcohol; Protein Binding; Protein Structure, Secondary; Solubility

2021
Chemoenzymatic semisynthesis of caffeic acid β-phenethyl ester, an antioxidative component in propolis, from raw coffee bean extract.
    Bioscience, biotechnology, and biochemistry, 2021, Feb-24, Volume: 85, Issue:3

    Topics: Antioxidants; Caffeic Acids; Coffea; Esterification; Phenylethyl Alcohol; Plant Extracts; Propolis

2021
Antioxidant effect of caffeic acid phenethyl ester in experimentally induced periodontitis.
    Clinical oral investigations, 2021, Volume: 25, Issue:8

    Topics: Animals; Antioxidants; Caffeic Acids; Oxidative Stress; Periodontitis; Phenylethyl Alcohol; Rats

2021
IL-8 as a Potential Therapeutic Target for Periodontitis and Its Inhibition by Caffeic Acid Phenethyl Ester In Vitro.
    International journal of molecular sciences, 2021, Mar-31, Volume: 22, Issue:7

    Topics: Anti-Inflammatory Agents; Caffeic Acids; Cytokines; Heme Oxygenase-1; Humans; I-kappa B Proteins; Inflammation; Interleukin-8; Lipopolysaccharides; NF-kappa B; NF-KappaB Inhibitor alpha; Periodontitis; Phenylethyl Alcohol; Phosphorylation; Saliva; THP-1 Cells

2021
Investigation of potential inhibitor properties of ethanolic propolis extracts against ACE-II receptors for COVID-19 treatment by molecular docking study.
    Archives of microbiology, 2021, Volume: 203, Issue:6

    Topics: Angiotensin-Converting Enzyme 2; Animals; Bees; Caffeic Acids; COVID-19 Drug Treatment; Flavanones; Flavonoids; Hesperidin; Humans; Luteolin; Molecular Docking Simulation; Phenylethyl Alcohol; Plant Extracts; Propolis; Quercetin; Rutin

2021
Lycopene and Caffeic Acid Phenethyl Ester Affect Caspase-3 Activity, but Do Not Alter the NO Pathway in Lung Tissue Damage Induced by Cisplatin.
    Pharmacology, 2021, Volume: 106, Issue:7-8

    Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Caffeic Acids; Caspase 3; Cisplatin; Lipid Peroxidation; Lung; Lycopene; Male; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Reactive Oxygen Species

2021
Analysis of the Effect of N555 Mutations on the Product Specificity of Dextransucrase Using Caffeic Acid Phenethyl Ester as an Acceptor Substrate.
    Journal of agricultural and food chemistry, 2021, May-26, Volume: 69, Issue:20

    Topics: Caffeic Acids; Glucosyltransferases; Mutation; Phenylethyl Alcohol

2021
Neuroprotective Potential of Caffeic Acid Phenethyl Ester (CAPE) in CNS Disorders: Mechanistic and Therapeutic Insights.
    Current neuropharmacology, 2021, Volume: 19, Issue:9

    Topics: Aged; Anti-Inflammatory Agents; Antioxidants; Caffeic Acids; Humans; Phenylethyl Alcohol

2021
Icariin, Formononetin and Caffeic Acid Phenethyl Ester Inhibit Feline Calicivirus Replication In Vitro.
    Archives of virology, 2021, Volume: 166, Issue:9

    Topics: Animals; Antiviral Agents; Caffeic Acids; Caliciviridae Infections; Calicivirus, Feline; Cat Diseases; Cats; Cell Line; Cell Survival; Drug Interactions; Flavonoids; Isoflavones; Phenylethyl Alcohol; Virus Replication

2021
Caffeic Acid Phenethyl Ester-Incorporated Radio-Sensitive Nanoparticles of Phenylboronic Acid Pinacol Ester-Conjugated Hyaluronic Acid for Application in Radioprotection.
    International journal of molecular sciences, 2021, Jun-14, Volume: 22, Issue:12

    Topics: Animals; Boronic Acids; Caffeic Acids; Cell Line; Cell Survival; Drug Liberation; Glycols; Hyaluronic Acid; Hydrogen Peroxide; Liver; Mice, Inbred BALB C; Nanoparticles; Particle Size; Phenylethyl Alcohol; Proton Magnetic Resonance Spectroscopy; Radiation Protection; Spectroscopy, Fourier Transform Infrared

2021
Low concentrations of caffeic acid phenethyl ester stimulate osteogenesis in vitro.
    Tissue & cell, 2021, Volume: 73

    Topics: Alkaline Phosphatase; Bone Matrix; Caffeic Acids; Calcification, Physiologic; Cell Line; Cell Survival; Core Binding Factor Alpha 1 Subunit; Gene Expression Regulation; Humans; Osteocalcin; Osteogenesis; Osteopontin; Phenylethyl Alcohol

2021
Caffeic Acid Phenethyl Ester Loaded Electrospun Nanofibers for Wound Dressing Application.
    Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bandages; Caffeic Acids; Humans; Nanofibers; Phenylethyl Alcohol; Pseudomonas aeruginosa; Staphylococcus aureus

2022
CAPE-pNO
    Life sciences, 2021, Dec-15, Volume: 287

    Topics: Alzheimer Disease; Animals; Animals, Outbred Strains; Autophagy; Brain Injuries; Caffeic Acids; Cell Line; Diabetes Mellitus, Experimental; Inflammation; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Phenylethyl Alcohol

2021
Investigation of the anti-inflammatory effects of caffeic acid phenethyl ester in a model of λ-Carrageenan-induced paw edema in rats.
    Human & experimental toxicology, 2021, Volume: 40, Issue:12_suppl

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Carrageenan; Disease Models, Animal; Edema; Male; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley

2021
Caffeic acid phenethyl ester mitigates infertility: A crucial role of metalloproteinase and angiogenic factor in cadmium-induced testicular damage.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:2

    Topics: Animals; Apoptosis; Cadmium; Caffeic Acids; Infertility, Male; Male; Matrix Metalloproteinase 3; Mice; Phenylethyl Alcohol; Spermatogenesis; Testis; Vascular Endothelial Growth Factor A

2022
Anti-tumour potential and selectivity of caffeic acid phenethyl ester in osteosarcoma cells.
    Tissue & cell, 2022, Volume: 74

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Mice; Osteosarcoma; Phenylethyl Alcohol

2022
Caffeic acid phenethyl ester protects against doxorubicin-induced cardiotoxicity and increases chemotherapeutic efficacy by regulating the unfolded protein response.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 159

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Caffeic Acids; Cardiotoxins; Cell Line, Tumor; Doxorubicin; Endoplasmic Reticulum Stress; Female; Mice; Mice, Inbred BALB C; Phenylethyl Alcohol; Propolis; Protective Agents; Rats; Unfolded Protein Response

2022
Caffeic acid phenethyl ester targets ubiquitin-specific protease 8 and synergizes with cisplatin in endometrioid ovarian carcinoma cells.
    Biochemical pharmacology, 2022, Volume: 197

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Cisplatin; Drug Delivery Systems; Endopeptidases; Endosomal Sorting Complexes Required for Transport; Female; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Phenylethyl Alcohol; Ubiquitin Thiolesterase; Xenograft Model Antitumor Assays

2022
Caffeic acid phenethyl ester induces radiosensitization via inhibition of DNA damage repair in androgen-independent prostate cancer cells.
    Environmental toxicology, 2022, Volume: 37, Issue:5

    Topics: Androgens; Apoptosis; Caffeic Acids; Cell Line, Tumor; DNA Damage; DNA Repair; Humans; Male; Phenylethyl Alcohol; Prostatic Neoplasms

2022
Effects of low dose doxycycline and caffeic acid phenethyl ester on sclerostin and bone morphogenic protein-2 expressions in experimental periodontitis.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2022, Volume: 97, Issue:8

    Topics: Animals; Caffeic Acids; Doxycycline; Male; Periodontitis; Phenylethyl Alcohol; Rats

2022
Combination treatment of docetaxel with caffeic acid phenethyl ester suppresses the survival and the proliferation of docetaxel-resistant prostate cancer cells via induction of apoptosis and metabolism interference.
    Journal of biomedical science, 2022, Feb-23, Volume: 29, Issue:1

    Topics: Androgen Antagonists; Animals; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Docetaxel; Humans; Male; Mice; Mice, Nude; Phenylethyl Alcohol; Prostatic Neoplasms; Quality of Life

2022
Antiradical properties of curcumin, caffeic acid phenethyl ester, and chicoric acid: a DFT study.
    Journal of molecular modeling, 2022, Feb-26, Volume: 28, Issue:3

    Topics: Caffeic Acids; Curcumin; Phenylethyl Alcohol; Succinates

2022
Design and synthesis of novel caffeic acid phenethyl ester (CAPE) derivatives and their biological activity studies in glioblastoma multiforme (GBM) cancer cell lines.
    Journal of molecular graphics & modelling, 2022, Volume: 113

    Topics: Caffeic Acids; Cell Line; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Molecular Docking Simulation; Phenylethyl Alcohol

2022
Interaction between caffeic acid phenethyl ester and protease: monitoring by spectroscopic and molecular docking approaches.
    Luminescence : the journal of biological and chemical luminescence, 2022, Volume: 37, Issue:6

    Topics: Caffeic Acids; Molecular Docking Simulation; Pepsin A; Peptide Hydrolases; Phenylethyl Alcohol; Spectrometry, Fluorescence; Trypsin

2022
In Vitro Antimicrobial Potential of CAPE and Caffeamide Derivatives against Oral Microbes.
    International journal of molecular sciences, 2022, Apr-07, Volume: 23, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Caffeic Acids; Methicillin-Resistant Staphylococcus aureus; Phenylethyl Alcohol

2022
Caffeic acid phenethyl ester alleviated hypouricemia in hyperuricemic mice through inhibiting XOD and up-regulating OAT3.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 103

    Topics: Animals; Caffeic Acids; Hyperuricemia; Kidney; Mice; Molecular Docking Simulation; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Oxonic Acid; Phenylethyl Alcohol; RNA, Messenger; Uric Acid; Xanthine Oxidase

2022
Caffeic acid phenethyl ester inhibits pseudo-allergic reactions via inhibition of MRGPRX2/MrgprB2-dependent mast cell degranulation.
    Archives of pharmacal research, 2022, Volume: 45, Issue:9

    Topics: Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Caffeic Acids; Cell Degranulation; Humans; Hypersensitivity; Mast Cells; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Nerve Tissue Proteins; p-Methoxy-N-methylphenethylamine; Phenylethyl Alcohol; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Secretagogues

2022
Caffeic acid phenethyl ester ameliorates imidacloprid-induced acute toxicity in the rat cerebral cortex.
    Environmental toxicology and pharmacology, 2022, Volume: 96

    Topics: Animals; Antioxidants; Caffeic Acids; Cerebral Cortex; Oxidative Stress; Phenylethyl Alcohol; Rats

2022
Caffeic acid phenethyl ester loaded in a targeted delivery system based on a solid-in-oil-in-water multilayer emulsion: Characterization, stability, and fate of the emulsion during in vivo digestion.
    Food research international (Ottawa, Ont.), 2022, Volume: 161

    Topics: Antioxidants; Caffeic Acids; Caseins; Cholates; Coconut Oil; Digestion; Emulsions; Lecithins; Phenylethyl Alcohol; Sodium; Water

2022
Co-assembling nanoparticles of Asiatic acid and Caffeic acid phenethyl ester: Characterization, stability and bioactivity in vitro.
    Food chemistry, 2023, Feb-15, Volume: 402

    Topics: Caffeic Acids; Nanoparticles; Phenylethyl Alcohol; Water

2023
Inhibition of focal adhesion kinase/paxillin axis by caffeic acid phenethyl ester restrains aggressive behaviors of head and neck squamous cell carcinoma in vitro.
    Archives of oral biology, 2023, Volume: 146

    Topics: Cadherins; Caffeic Acids; Cell Line, Tumor; Cell Movement; Focal Adhesion Protein-Tyrosine Kinases; Head and Neck Neoplasms; Humans; Paxillin; Phenylethyl Alcohol; Squamous Cell Carcinoma of Head and Neck

2023
Computational and experimental evidence of the anti-COVID-19 potential of honeybee propolis ingredients, caffeic acid phenethyl ester and artepillin c.
    Phytotherapy research : PTR, 2023, Volume: 37, Issue:9

    Topics: Animals; Bees; Caffeic Acids; Phenylethyl Alcohol; Propolis

2023
Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE-19 Cells.
    International journal of molecular sciences, 2023, Feb-10, Volume: 24, Issue:4

    Topics: Antioxidants; Apoptosis; Caffeic Acids; Humans; Oxidative Stress; Phenylethyl Alcohol; Reactive Oxygen Species

2023
Phosphorylated walnut protein/chitosan nanocomplexes as promising carriers for encapsulation of caffeic acid phenethyl ester.
    Journal of the science of food and agriculture, 2023, Volume: 103, Issue:12

    Topics: Caffeic Acids; Chitosan; Juglans; Phenylethyl Alcohol

2023
Effects of Temperature, Metal Ions and Biosurfactants on Interaction Mechanism between Caffeic Acid Phenethyl Ester and Hemoglobin.
    Molecules (Basel, Switzerland), 2023, Apr-13, Volume: 28, Issue:8

    Topics: Caffeic Acids; Hemoglobins; Molecular Docking Simulation; Phenylethyl Alcohol; Temperature

2023
Investigation into Propolis Components Responsible for Inducing Skin Allergy: Air Oxidation of Caffeic Acid and Its Esters Contribute to Hapten Formation.
    Chemical research in toxicology, 2023, 06-19, Volume: 36, Issue:6

    Topics: Cysteine; Esters; Haptens; Humans; Hypersensitivity; Phenylethyl Alcohol; Propolis

2023
Caffeic acid phenethyl ester suppresses EGFR/FAK/Akt signaling, migration, and tumor growth of prostate cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Jul-25, Volume: 116

    Topics: Animals; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Humans; Male; Mice; Mice, Nude; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt

2023
Intralipid and caffeic acid phenethyl ester reverse the neurotoxic effects of organophosphate poisoning in rats.
    Nigerian journal of clinical practice, 2023, Volume: 26, Issue:6

    Topics: Animals; Antioxidants; Caffeic Acids; Organophosphate Poisoning; Organophosphates; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar

2023
Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells by inactivating FGFR1 via MD2.
    PloS one, 2023, Volume: 18, Issue:7

    Topics: Breast Neoplasms; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Female; Humans; Phenylethyl Alcohol; Receptor, Fibroblast Growth Factor, Type 1

2023
Caffeic Acid Phenethyl Ester (CAPE) Synergistically Enhances Paclitaxel Activity in Ovarian Cancer Cells.
    Molecules (Basel, Switzerland), 2023, Aug-01, Volume: 28, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Female; Humans; Ovarian Neoplasms; Paclitaxel; Phenylethyl Alcohol

2023