Compounds > caffeic acid phenethyl ester
Page last updated: 2024-09-02

caffeic acid phenethyl ester and paclitaxel

caffeic acid phenethyl ester has been researched along with paclitaxel in 9 studies

Compound Research Comparison

Studies
(caffeic acid phenethyl ester)		Trials
(caffeic acid phenethyl ester)		Recent Studies (post-2010)
(caffeic acid phenethyl ester)		Studies
(paclitaxel)		Trials
(paclitaxel)		Recent Studies (post-2010) (paclitaxel)
840146931,8745,72915,395

Protein Interaction Comparison

ProteinTaxonomycaffeic acid phenethyl ester (IC50)paclitaxel (IC50)
Integrin beta-3Homo sapiens (human)0.034
Integrin alpha-V Homo sapiens (human)0.034
ATP-dependent translocase ABCB1Homo sapiens (human)2.598
Botulinum neurotoxin type A Clostridium botulinum5.2
UDP-glucuronosyltransferase 2B7Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1-6Homo sapiens (human)4.9
Substance-K receptorHomo sapiens (human)6.125
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1A4Homo sapiens (human)4.9
UDP-glucuronosyltransferase 2B10 Homo sapiens (human)4.9
Delta-type opioid receptorHomo sapiens (human)4.202
Tyrosine-protein kinase MerHomo sapiens (human)4.9
Tubulin beta-3 chainHomo sapiens (human)0.0082
Beta-tubulin Leishmania donovani1
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)7.9433
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)0.26
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.28

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Fu, L; Ge, Y; Lam, C; Qiao, Y; Xiao, J; Xie, D; Xie, J; Yang, F; Zhang, D; Zhang, M1
Coffey, R; Fitzpatrick, JM; McEleny, K; Morrissey, C; Watson, RW1
Abdel-Naim, AB; Abdel-Rahman, SZ; Al-Abd, AM; Azab, SS; Esmat, A; Khalifa, AE; Mosli, HA; Tolba, MF1
Grabow, N; Guthoff, RF; Reske, T; Schmidt, W; Schmitz, KP; Siewert, S; Stahnke, T; Wree, A1
Kulkarni, NP; Narula, AS; Sharma, SS; Vaidya, B1
Dzik, R; Kabała-Dzik, A; Kleczka, A1

Other Studies

9 other study(ies) available for caffeic acid phenethyl ester and paclitaxel

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Antiproliferative activity and SARs of caffeic acid esters with mono-substituted phenylethanols moiety.
    Bioorganic & medicinal chemistry letters, 2017, 01-15, Volume: 27, Issue:2

    Topics: Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Esters; Humans; Phenylethyl Alcohol; Structure-Activity Relationship

2017
Caffeic acid phenethyl ester-induced PC-3 cell apoptosis is caspase-dependent and mediated through the loss of inhibitors of apoptosis proteins.
    BJU international, 2004, Volume: 94, Issue:3

    Topics: Apoptosis; Blotting, Western; Caffeic Acids; Caspase Inhibitors; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Male; NF-kappa B; Paclitaxel; Phenylethyl Alcohol; Prostatic Neoplasms; Tumor Necrosis Factor-alpha

2004
Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells.
    IUBMB life, 2013, Volume: 65, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Docetaxel; Drug Synergism; Estrogen Receptor alpha; Estrogen Receptor beta; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Inhibitory Concentration 50; Male; Paclitaxel; Phenylethyl Alcohol; Prostatic Neoplasms; Taxoids

2013
Development of a biodegradable antifibrotic local drug delivery system for glaucoma microstents.
    Bioscience reports, 2018, 08-31, Volume: 38, Issue:4

    Topics: Animals; Caffeic Acids; Drug Delivery Systems; Drug-Eluting Stents; Fibrosis; Glaucoma; Male; Paclitaxel; Phenylethyl Alcohol; Pyridones; Rats; Rats, Wistar

2018
Caffeic Acid Phenethyl Ester (CAPE) Attenuates Paclitaxel-induced Peripheral Neuropathy: A Mechanistic Study.
    Current neurovascular research, 2022, Volume: 19, Issue:3

    Topics: Animals; Antineoplastic Agents; beta Catenin; Female; Matrix Metalloproteinase 2; Neuralgia; Paclitaxel; Rats; Rats, Sprague-Dawley; Wnt Signaling Pathway

2022
Caffeic Acid Phenethyl Ester (CAPE) Synergistically Enhances Paclitaxel Activity in Ovarian Cancer Cells.
    Molecules (Basel, Switzerland), 2023, Aug-01, Volume: 28, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Female; Humans; Ovarian Neoplasms; Paclitaxel; Phenylethyl Alcohol

2023