caffeic acid phenethyl ester has been researched along with methotrexate in 10 studies
| Studies (caffeic acid phenethyl ester) | Trials (caffeic acid phenethyl ester) | Recent Studies (post-2010) (caffeic acid phenethyl ester) | Studies (methotrexate) | Trials (methotrexate) | Recent Studies (post-2010) (methotrexate) |
|---|---|---|---|---|---|
| 840 | 1 | 469 | 41,593 | 5,666 | 11,969 |
| Protein | Taxonomy | caffeic acid phenethyl ester (IC50) | methotrexate (IC50) |
|---|---|---|---|
| Thymidylate synthase | Escherichia coli | 1.8 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 0.211 | |
| Toll-like receptor 4 | Homo sapiens (human) | 1.04 | |
| Fatty-acid amide hydrolase 1 | Mus musculus (house mouse) | 0.08 | |
| Dihydrofolate reductase | Homo sapiens (human) | 0.0522 | |
| Dihydrofolate reductase | Mus musculus (house mouse) | 0.0331 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.0348 | |
| Dihydrofolate reductase | Gallus gallus (chicken) | 0.0545 | |
| Dihydrofolate reductase | Enterococcus faecium | 0.0014 | |
| Dihydrofolate reductase | Lacticaseibacillus casei | 0.0138 | |
| Thymidylate synthase | Homo sapiens (human) | 0.343 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0147 | |
| Thymidylate synthase | Escherichia coli K-12 | 0.0181 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.1529 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 0.084 | |
| Folate receptor beta | Homo sapiens (human) | 0.1585 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0011 | |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | 0.0012 | |
| Folate receptor alpha | Homo sapiens (human) | 0.2263 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.0717 | |
| Histidine decarboxylase | Rattus norvegicus (Norway rat) | 0.0014 | |
| Trifunctional purine biosynthetic protein adenosine-3 | Homo sapiens (human) | 0.01 | |
| Bifunctional purine biosynthesis protein ATIC | Homo sapiens (human) | 0.01 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Reduced folate transporter | Homo sapiens (human) | 0.012 | |
| Dihydrofolate reductase | Mycobacterium tuberculosis H37Rv | 0.0174 | |
| Folylpolyglutamate synthase, mitochondrial | Homo sapiens (human) | 3.2 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 0.0547 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Trypanosoma cruzi | 0.11 | |
| Dihydrofolate reductase | Bacillus anthracis | 0.0136 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 0.0047 | |
| Proton-coupled folate transporter | Homo sapiens (human) | 0.1207 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (80.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Blijlevens, NM; de Witte, TJ; Donnelly, JP; M'Rabet, L; Marteijn, J; Timal, S; van't Land, B | 1 |
| Oktem, F; Ozgüner, F; Uz, E; Uzar, E; Yilmaz, HR | 1 |
| Bas, O; Kilbas, S; Koyuncuoglu, HR; Kucuker, H; Sahin, O; Songur, A; Uz, E; Uzar, E; Yilmaz, HR; Yurekli, VA | 1 |
| Gultekin, F; Kilbas, S; Koyuncuoglu, HR; Kutluhan, S; Uz, E; Uzar, E; Yilmaz, HR | 1 |
| Ayata, A; Oktem, F; Olgar, S; Ozguner, F; Uz, E; Uzare, E; Yilmaz, HR | 1 |
| Armagan, A; Cam, H; Koyuncuoglu, HR; Kutluhan, S; Serel, TA; Soyupek, S; Uz, E; Uzar, E; Yilmaz, HR | 1 |
| Çakır, T; Dulundu, E; Ercan, F; Özkan, E; Şehirli, AÖ; Şener, E; Şener, G; Topaloğlu, Ü | 1 |
| Baykal, B; Elbey, B; Keskin, I; Kuş, S; Şahin, A; Yazgan, ÜC; Yılmaz, A | 1 |
10 other study(ies) available for caffeic acid phenethyl ester and methotrexate
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Role of curcumin and the inhibition of NF-kappaB in the onset of chemotherapy-induced mucosal barrier injury.
Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line; Curcumin; Cytarabine; Drug Interactions; Female; Intestinal Mucosa; Methotrexate; NF-kappa B; Phenylethyl Alcohol; Rats; Rats, Inbred Strains | 2004 |
The activities of purine-catabolizing enzymes and the level of nitric oxide in rat kidneys subjected to methotrexate: protective effect of caffeic acid phenethyl ester.
Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Caffeic Acids; Folic Acid Antagonists; Free Radical Scavengers; Kidney; Male; Methotrexate; Nitric Oxide; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Xanthine Oxidase | 2005 |
The activity of adenosine deaminase and the level of nitric oxide in spinal cord of methotrexate administered rats: protective effect of caffeic acid phenethyl ester.
Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antioxidants; Antirheumatic Agents; Caffeic Acids; Male; Methotrexate; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Protective Agents; Rats; Rats, Wistar; Spinal Cord | 2006 |
The activities of antioxidant enzymes and the level of malondialdehyde in cerebellum of rats subjected to methotrexate: protective effect of caffeic acid phenethyl ester.
Topics: Animals; Antioxidants; Caffeic Acids; Catalase; Cerebellum; Male; Malondialdehyde; Methotrexate; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2006 |
Methotrexate-induced renal oxidative stress in rats: the role of a novel antioxidant caffeic acid phenethyl ester.
Topics: Animals; Caffeic Acids; Catalase; Free Radical Scavengers; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Methotrexate; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2006 |
Caffeic acid phenethyl ester modulates methotrexate-induced oxidative stress in testes of rat.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Caffeic Acids; Cytotoxins; Drug Antagonism; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Methotrexate; Organ Size; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase; Testis | 2008 |
Caffeic acid phenethyl ester (CAPE) prevents methotrexate-induced hepatorenal oxidative injury in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Caffeic Acids; Chemical and Drug Induced Liver Injury; Female; Glutathione; Interleukin-1beta; Kidney Diseases; Male; Malondialdehyde; Methotrexate; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tumor Necrosis Factor-alpha | 2011 |
Effect of caffeic acid phenethyl ester on oxidant and anti-oxidant status of liver and serum in a rat model with acute methanol intoxication.
Topics: Animals; Antioxidants; Caffeic Acids; Disease Models, Animal; Ethanol; Liver; Male; Methanol; Methotrexate; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley | 2017 |