Protein | Taxonomy | caffeic acid phenethyl ester (IC50) | epigallocatechin gallate (IC50) |
Chain A, POLYMERASE PA | Influenza A virus | | 1.9 |
Chain A, Polymerase Pa | Influenza A virus (A/California/04/2009(H1N1)) | | 1.9 |
Chain A, Polymerase Pa | Influenza A virus (A/California/04/2009(H1N1)) | | 1.9 |
Chain A, Polymerase Pa | Influenza A virus (A/California/04/2009(H1N1)) | | 1.9 |
Chain A, Polymerase Pa | Influenza A virus (A/California/04/2009(H1N1)) | | 1.9 |
Prostaglandin E synthase | Homo sapiens (human) | | 1.8 |
Telomerase reverse transcriptase | Homo sapiens (human) | | 1.0867 |
NAD kinase | Homo sapiens (human) | | 0.96 |
Urokinase-type plasminogen activator | Homo sapiens (human) | | 0.091 |
Tissue-type plasminogen activator | Homo sapiens (human) | | 0.091 |
Polymerase acidic protein | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | | 5.86 |
Amyloid-beta precursor protein | Homo sapiens (human) | | 2.7 |
Plasminogen activator inhibitor 1 | Homo sapiens (human) | | 0.091 |
Urokinase-type plasminogen activator | Mus musculus (house mouse) | | 0.091 |
ATP-dependent translocase ABCB1 | Homo sapiens (human) | | 0.1233 |
72 kDa type IV collagenase | Homo sapiens (human) | | 4.3833 |
Hepatocyte growth factor receptor | Homo sapiens (human) | | 10 |
Matrilysin | Homo sapiens (human) | | 3.34 |
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Escherichia coli K-12 | | 5 |
Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | | 1.15 |
Apoptosis regulator Bcl-2 | Homo sapiens (human) | | 0.45 |
Microtubule-associated protein tau | Homo sapiens (human) | | 1.8 |
60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | | 2.3 |
Glucose-6-phosphate 1-dehydrogenase | Saccharomyces cerevisiae S288C | | 0.25 |
Lethal factor | Bacillus anthracis | | 0.097 |
Phosphoglycerate mutase 1 | Homo sapiens (human) | | 0.49 |
DNA (cytosine-5)-methyltransferase 1 | Homo sapiens (human) | | 0.5 |
Proteasome subunit beta type-5 | Homo sapiens (human) | | 0.543 |
DNA repair protein RAD52 homolog | Homo sapiens (human) | | 2.5108 |
Matrix metalloproteinase-14 | Homo sapiens (human) | | 6.8 |
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 | Homo sapiens (human) | | 3.34 |
Squalene monooxygenase | Rattus norvegicus (Norway rat) | | 0.69 |
6-phosphogluconate dehydrogenase, decarboxylating | Homo sapiens (human) | | 0.72 |
BH3-interacting domain death agonist | Homo sapiens (human) | | 1.0733 |
Beta-secretase 1 | Homo sapiens (human) | | 1.1785 |
10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | | 2.3 |
Bcl-2-like protein 1 | Homo sapiens (human) | | 0.59 |
Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | | 0.92 |
Alpha-(1,3)-fucosyltransferase 7 | Homo sapiens (human) | | 3.34 |
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | Homo sapiens (human) | | 3.34 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | | 0.3055 |
Mitogen-activated protein kinase 14 | Homo sapiens (human) | | 2.21 |
Bcl-2-related protein A1 | Homo sapiens (human) | | 1.79 |
Thiosulfate sulfurtransferase | Homo sapiens (human) | | 7.3 |
60 kDa chaperonin | Escherichia coli | | 0.47 |
Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | | 10 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | | 0.33 |
Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | | 0.73 |
10 kDa chaperonin | Escherichia coli | | 0.47 |
3-oxoacyl-[acyl-carrier-protein] reductase | Plasmodium falciparum 3D7 | | 0.32 |
MAP kinase-activated protein kinase 5 | Homo sapiens (human) | | 1 |
Bcl-2-like protein 2 | Homo sapiens (human) | | 2.33 |
Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | | 0.225 |
3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | | 0.3 |
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | | 0.215 |
Bcl-2-like protein 10 | Homo sapiens (human) | | 0.36 |
Authors | Studies |
Backlund, A; Bohlin, L; Gottfries, J; Larsson, J | 1 |
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
Bao, J; Chandna, R; Dsouza, C; Fu, L; Ge, R; He, W; Jiang, F; Jin, Y; Matthews, AA; Qiao, Y | 1 |
Bhimani, RS; Frenkel, K; Grunberger, D; Troll, W | 1 |
Cheng, IC; Lee, TC; Shue, JJ; Wang, TC | 1 |
Calabrese, V; Caruso, C; Scapagnini, G | 1 |
6 other study(ies) available for caffeic acid phenethyl ester and epigallocatechin gallate
Article | Year |
Expanding the ChemGPS chemical space with natural products.Journal of natural products, 2005, Volume: 68, Issue:7
Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2005 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Discovery of small molecules targeting GRP78 for antiangiogenic and anticancer therapy.European journal of medicinal chemistry, 2020, May-01, Volume: 193Topics: 3T3 Cells; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; Mice; Molecular Docking Simulation; Molecular Structure; Small Molecule Libraries; Structure-Activity Relationship | 2020 |
Inhibition of oxidative stress in HeLa cells by chemopreventive agents.Cancer research, 1993, Oct-01, Volume: 53, Issue:19
Topics: 8-Hydroxy-2'-Deoxyguanosine; Anticarcinogenic Agents; Antineoplastic Agents; Caffeic Acids; Catechin; Deoxyguanosine; Diterpenes; DNA, Neoplasm; HeLa Cells; Humans; Hydrogen Peroxide; Hydrolyzable Tannins; Oxidation-Reduction; Phenylethyl Alcohol; Tamoxifen; Tannins; Tetradecanoylphorbol Acetate; Thymidine | 1993 |
Cytotoxicity of arsenic trioxide is enhanced by (-)-epigallocatechin-3-gallate via suppression of ferritin in cancer cells.Toxicology and applied pharmacology, 2011, Jan-01, Volume: 250, Issue:1
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caffeic Acids; Catechin; Cell Line, Tumor; Cytotoxins; Drug Synergism; Ferritins; Heme Oxygenase (Decyclizing); HL-60 Cells; Humans; Neoplasms; Oxides; Phenylethyl Alcohol | 2011 |
Therapeutic potential of dietary polyphenols against brain ageing and neurodegenerative disorders.Advances in experimental medicine and biology, 2010, Volume: 698Topics: Aging; Antioxidants; Brain; Caffeic Acids; Catechin; Curcumin; Diet; Flavonoids; Neurodegenerative Diseases; Neuroprotective Agents; Phenols; Phenylethyl Alcohol; Polyphenols | 2010 |