Page last updated: 2024-09-02

caffeic acid phenethyl ester and dinoprostone

caffeic acid phenethyl ester has been researched along with dinoprostone in 6 studies

Compound Research Comparison

Studies
(caffeic acid phenethyl ester)
Trials
(caffeic acid phenethyl ester)
Recent Studies (post-2010)
(caffeic acid phenethyl ester)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
840146929,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomycaffeic acid phenethyl ester (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Carothers, AM; Dannenberg, AJ; Grunberger, D; Koboldt, C; Masferrer, JL; Mestre, JR; Michaluart, P; Sacks, PG; Subbaramaiah, K; Tanabe, T; Zweifel, BS1
Borrelli, F; Ligresti, A; Longo, R; Rossi, A; Russo, A; Sautebin, L1
Borrelli, F; Longo, R; Rossi, A; Russo, A; Sautebin, L1
Mayhan, WG; Miller, DW; Trickler, WJ1
Choi, I; Choi, IW; Choi, YH; Jung, WK; Kim, MM; Lee, CM; Lee, DY; Lee, SW; Park, SG; Park, YM; Seo, SK; Yea, SS1

Other Studies

6 other study(ies) available for caffeic acid phenethyl ester and dinoprostone

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.
    Cancer research, 1999, May-15, Volume: 59, Issue:10

    Topics: Air; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arachidonic Acids; Caffeic Acids; Calcimycin; Carcinoma, Squamous Cell; Carrageenan; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Genetic Vectors; Humans; Indomethacin; Inflammation; Ionophores; Isoenzymes; Male; Membrane Lipids; Membrane Proteins; Mouth Mucosa; Nucleopolyhedroviruses; Phenylethyl Alcohol; Phospholipids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1999
The inhibitory effect of propolis and caffeic acid phenethyl ester on cyclooxygenase activity in J774 macrophages.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2002, Volume: 9, Issue:6

    Topics: Animals; Caffeic Acids; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Flavonoids; Isoenzymes; Macrophages; Phenylethyl Alcohol; Propolis; Prostaglandin-Endoperoxide Synthases

2002
The role of the phenethyl ester of caffeic acid (CAPE) in the inhibition of rat lung cyclooxygenase activity by propolis.
    Fitoterapia, 2002, Volume: 73 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Flavonoids; Inhibitory Concentration 50; Lipopolysaccharides; Lung; Male; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Propolis; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar

2002
Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway.
    Brain research, 2005, Jun-28, Volume: 1048, Issue:1-2

    Topics: Animals; Blotting, Western; Brain; Caffeic Acids; Capillary Permeability; Cattle; Cells, Cultured; Dextrans; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; NF-kappa B; Nitriles; Oncogene Proteins v-rel; Phenylethyl Alcohol; Proline; Signal Transduction; Sulfones; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha

2005
Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-kappaB pathways.
    The international journal of biochemistry & cell biology, 2008, Volume: 40, Issue:11

    Topics: Animals; Caffeic Acids; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Shock, Septic; Signal Transduction; Tumor Necrosis Factor-alpha

2008