Page last updated: 2024-09-02

caffeic acid phenethyl ester and benzyl caffeate

caffeic acid phenethyl ester has been researched along with benzyl caffeate in 14 studies

Compound Research Comparison

Studies
(caffeic acid phenethyl ester)
Trials
(caffeic acid phenethyl ester)
Recent Studies (post-2010)
(caffeic acid phenethyl ester)
Studies
(benzyl caffeate)
Trials
(benzyl caffeate)
Recent Studies (post-2010) (benzyl caffeate)
84014691507

Protein Interaction Comparison

ProteinTaxonomycaffeic acid phenethyl ester (IC50)benzyl caffeate (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)0.21
Aldo-keto reductase family 1 member B1Homo sapiens (human)0.4
Integrase Human immunodeficiency virus 18.9563

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's5 (35.71)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bankova, V; Manolova, N; Serkedjieva, J1
Burke, TR; Carothers, AM; Driscoll, J; Fesen, MR; Grunberger, D; Kohn, K; Mazumder, A; Pommier, Y; Wang, J1
Assefa, H; Buolamwini, JK1
Banskota, AH; Kadota, S; Matsushige, K; Midorikawa, K; Tezuka, Y; Usia, T1
Imaizumi, T; Ishikawa, M; Kanno, S; Osanai, Y; Takeshita, M; Uwai, K1
Hu, WX; Li, HB; Liu, F; Xia, CN1
Antonini, G; Cechinel Filho, V; de Campos Buzzi, F; Fracasso, M; Franzoi, CL; Niero, R; Yunes, RA1
El-Kabbani, O; Endo, S; Hara, A; Hu, D; Ifuku, S; Li, J; Matsunaga, T; Ohta, S; Soda, M; Takemura, M; Toyooka, N; Wada, R; Yamamura, K; Zhao, HT1
Clabault, H; Hébert, MJ; Jean-François, J; Lassalle-Claux, G; Paré, AF; Patton, C; Sanderson, JT; Surette, ME; Touaibia, M1
Han, MS; Kim, DW; Lee, IK; Yun, BS1
Chen, HZ; Chen, LF; Chen, YB; Gao, JR; Li, HB; Lv, YP; Xia, CN; Zeng, F; Zhang, J; Zhou, BJ; Zhou, YL1
Kosaka, Y; Mizuguchi, M; Yokoyama, T1
Borges, F; Garrido, J; Martínez, A; Martínez-González, L; Mohamed, T; Pérez, DI; Rao, PP; Remião, F; Serrão, P; Shakeri, A; Silva, T; Soares-da-Silva, P; Uriarte, E; Valente, MJ1
Borges, F; Mohamed, T; Rao, PPN; Remião, F; Shakeri, A; Silva, T; Soares da Silva, P1

Other Studies

14 other study(ies) available for caffeic acid phenethyl ester and benzyl caffeate

ArticleYear
Anti-influenza virus effect of some propolis constituents and their analogues (esters of substituted cinnamic acids).
    Journal of natural products, 1992, Volume: 55, Issue:3

    Topics: Animals; Antiviral Agents; Chick Embryo; Chorion; Cinnamates; Coumaric Acids; Orthomyxoviridae; Orthomyxoviridae Infections; Propolis; Viral Plaque Assay; Virus Replication

1992
Hydroxylated aromatic inhibitors of HIV-1 integrase.
    Journal of medicinal chemistry, 1995, Oct-13, Volume: 38, Issue:21

    Topics: Animals; Antiviral Agents; Apoptosis; Base Sequence; Binding Sites; Caffeic Acids; Cell Line, Transformed; DNA; DNA Nucleotidyltransferases; Enzyme Inhibitors; HIV; Humans; Hydroxylation; Integrases; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Phenylethyl Alcohol; Rats; Structure-Activity Relationship; Tumor Cells, Cultured; Zinc Fingers

1995
CoMFA and CoMSIA 3D QSAR and docking studies on conformationally-restrained cinnamoyl HIV-1 integrase inhibitors: exploration of a binding mode at the active site.
    Journal of medicinal chemistry, 2002, Feb-14, Volume: 45, Issue:4

    Topics: Binding Sites; Cinnamates; HIV Integrase Inhibitors; HIV-1; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship

2002
Constituents of Chinese propolis and their antiproliferative activities.
    Journal of natural products, 2002, Volume: 65, Issue:5

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Caffeic Acids; China; Chromatography, Thin Layer; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavonoids; Free Radical Scavengers; Mice; Molecular Structure; Phenylethyl Alcohol; Picrates; Propolis; Spectrophotometry, Infrared; Tumor Cells, Cultured

2002
Inhibitory effect of the alkyl side chain of caffeic acid analogues on lipopolysaccharide-induced nitric oxide production in RAW264.7 macrophages.
    Bioorganic & medicinal chemistry, 2008, Aug-15, Volume: 16, Issue:16

    Topics: Animals; Caffeic Acids; Cell Line; Cell Survival; Formazans; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Nitric Oxide; Nitrites; Propolis; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Tetrazolium Salts

2008
Synthesis of trans-caffeate analogues and their bioactivities against HIV-1 integrase and cancer cell lines.
    Bioorganic & medicinal chemistry letters, 2008, Dec-15, Volume: 18, Issue:24

    Topics: Antineoplastic Agents; Binding Sites; Biotin; Caffeic Acids; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Enzyme-Linked Immunosorbent Assay; HIV Integrase; HIV Integrase Inhibitors; Humans; Inhibitory Concentration 50; Models, Chemical; Structure-Activity Relationship

2008
Antinociceptive properties of caffeic acid derivatives in mice.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Analgesics; Animals; Caffeic Acids; Mice; Molecular Structure; Pain; Structure-Activity Relationship

2009
Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B10.
    European journal of medicinal chemistry, 2012, Volume: 48

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Antineoplastic Agents; Caffeic Acids; Catalytic Domain; Cell Survival; Enzyme Inhibitors; HeLa Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Propolis; Spectrophotometry, Infrared; Structure-Activity Relationship; U937 Cells

2012
Antiproliferative, antiandrogenic and cytotoxic effects of novel caffeic acid derivatives in LNCaP human androgen-dependent prostate cancer cells.
    Bioorganic & medicinal chemistry, 2013, Nov-15, Volume: 21, Issue:22

    Topics: Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cinnamates; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Structure-Activity Relationship

2013
Phenylpropanoid acid esters from Korean propolis and their antioxidant activities.
    Bioorganic & medicinal chemistry letters, 2014, Aug-01, Volume: 24, Issue:15

    Topics: Antioxidants; Coumaric Acids; DNA Damage; Esters; Molecular Structure; Propolis; Republic of Korea

2014
Synthesis and antitumor activity of feruloyl and caffeoyl derivatives.
    Bioorganic & medicinal chemistry letters, 2014, Sep-15, Volume: 24, Issue:18

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Coumaric Acids; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; HL-60 Cells; Humans; Molecular Structure; Structure-Activity Relationship

2014
Inhibitory activities of propolis and its promising component, caffeic acid phenethyl ester, against amyloidogenesis of human transthyretin.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Amyloid Neuropathies, Familial; Amyloidosis; Caffeic Acids; Coumaric Acids; Masoprocol; Phenylethyl Alcohol; Prealbumin; Propolis

2014
Development of Blood-Brain Barrier Permeable Nitrocatechol-Based Catechol O-Methyltransferase Inhibitors with Reduced Potential for Hepatotoxicity.
    Journal of medicinal chemistry, 2016, 08-25, Volume: 59, Issue:16

    Topics: Animals; Benzophenones; Blood-Brain Barrier; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Survival; Dose-Response Relationship, Drug; Hepatocytes; Male; Models, Molecular; Molecular Structure; Nitriles; Nitrophenols; Rats; Rats, Wistar; Structure-Activity Relationship; Tolcapone

2016
Repurposing nitrocatechols: 5-Nitro-α-cyanocarboxamide derivatives of caffeic acid and caffeic acid phenethyl ester effectively inhibit aggregation of tau-derived hexapeptide AcPHF6.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Caffeic Acids; Catechols; Chelating Agents; Copper; Drug Design; Nitro Compounds; Peptides; Phenylethyl Alcohol; Polyphenols; Protein Aggregation, Pathological; Small Molecule Libraries; tau Proteins; Tauopathies

2019