Page last updated: 2024-09-02

caffeic acid phenethyl ester and artepillin c

caffeic acid phenethyl ester has been researched along with artepillin c in 10 studies

Compound Research Comparison

Studies
(caffeic acid phenethyl ester)
Trials
(caffeic acid phenethyl ester)
Recent Studies (post-2010)
(caffeic acid phenethyl ester)
Studies
(artepillin c)
Trials
(artepillin c)
Recent Studies (post-2010) (artepillin c)
840146988261

Protein Interaction Comparison

ProteinTaxonomycaffeic acid phenethyl ester (IC50)artepillin c (IC50)
Aldo-keto reductase family 1 member C3Homo sapiens (human)1

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's6 (60.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Hashimoto, K; Hasumi, K; Koshino, H; Takahashi, S; Tani, H; Tatefuji, T1
El-Kabbani, O; Endo, S; Hara, A; Hu, D; Ifuku, S; Li, J; Matsunaga, T; Ohta, S; Soda, M; Takemura, M; Toyooka, N; Wada, R; Yamamura, K; Zhao, HT1
El-Kabbani, O; Endo, S; Hara, A; Kanamori, A; Matsunaga, T; Nagai, H; Ohta, S; Otsuji, Y; Sundaram, K; Toyooka, N1
Ahn, MR; Maruta, H1
Nishioka, N; Tsuji, T; Yoshizumi, K1
Ahn, MR; Hashimoto, K; Hori, H; Kaji, K; Kumazawa, S; Kunimasa, K; Maruta, H; Mautner, V; Messerli, SM; Ohta, T; Tatefuji, T; Uto, Y; Yanagihara, M1
Chan, GC; Cheung, KW; Sze, DM1
Luo, Y; Maruta, H; Yanase, S1
Bhargava, P; Ishida, Y; Kaul, A; Kaul, SC; Mahanta, D; Terao, K; Wadhwa, R1
Basu, B; Ishida, Y; Kaul, A; Kaul, SC; Kumar, V; Meidinna, HN; Sari, AN; Sundar, D; Terao, K; Vrati, S; Wadhwa, R1

Reviews

3 review(s) available for caffeic acid phenethyl ester and artepillin c

ArticleYear
From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic PAK1-blockers/longevity-promoters for cancer therapy.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Click Chemistry; Drug Discovery; Humans; Longevity; Neoplasms; p21-Activated Kinases; Protein Kinase Inhibitors

2017
The immunomodulatory and anticancer properties of propolis.
    Clinical reviews in allergy & immunology, 2013, Volume: 44, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Caffeic Acids; Cell Line, Tumor; Humans; Immunologic Factors; Neoplasms; Neoplastic Stem Cells; Oncogene Proteins; Phenylethyl Alcohol; Phenylpropionates; Propolis; Signal Transduction; T-Lymphocyte Subsets; Tumor Microenvironment

2013
Experimental Evidence for Therapeutic Potentials of Propolis.
    Nutrients, 2021, Jul-24, Volume: 13, Issue:8

    Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents; Antioxidants; Brazil; Caffeic Acids; Humans; New Zealand; Phenylethyl Alcohol; Phenylpropionates; Propolis

2021

Other Studies

7 other study(ies) available for caffeic acid phenethyl ester and artepillin c

ArticleYear
Inhibitory activity of Brazilian green propolis components and their derivatives on the release of cys-leukotrienes.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Animals; Anti-Allergic Agents; Bees; Cell Line, Tumor; Cysteine; Histamine; Humans; Leukocytes; Leukotrienes; Propolis; Rhinitis, Allergic, Seasonal

2010
Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B10.
    European journal of medicinal chemistry, 2012, Volume: 48

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Antineoplastic Agents; Caffeic Acids; Catalytic Domain; Cell Survival; Enzyme Inhibitors; HeLa Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Propolis; Spectrophotometry, Infrared; Structure-Activity Relationship; U937 Cells

2012
Selective inhibition of human type-5 17β-hydroxysteroid dehydrogenase (AKR1C3) by baccharin, a component of Brazilian propolis.
    Journal of natural products, 2012, Apr-27, Volume: 75, Issue:4

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Brazil; Crystallography, X-Ray; Humans; Hydroxyprostaglandin Dehydrogenases; Male; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Propolis; Stereoisomerism; Trichothecenes

2012
[Xanthine oxidase inhibitory activity and hypouricemia effect of propolis in rats].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:3

    Topics: Animals; Anti-Infective Agents; Brazil; Caffeic Acids; China; Coumaric Acids; Disease Models, Animal; Flavonoids; Gout; Hyperuricemia; Male; Oxonic Acid; Phenylethyl Alcohol; Phenylpropionates; Propionates; Propolis; Rats; Rats, Sprague-Dawley; Uric Acid; Xanthine Oxidase

2005
Artepillin C (ARC) in Brazilian green propolis selectively blocks oncogenic PAK1 signaling and suppresses the growth of NF tumors in mice.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:3

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Female; Mice; Mice, Nude; Neoplasms, Experimental; Neurofibromatoses; p21-Activated Kinases; Phenylethyl Alcohol; Phenylpropionates; Propolis; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays

2009
PAK1-deficiency/down-regulation reduces brood size, activates HSP16.2 gene and extends lifespan in Caenorhabditis elegans.
    Drug discoveries & therapeutics, 2013, Volume: 7, Issue:1

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caffeic Acids; Down-Regulation; Green Fluorescent Proteins; Heat-Shock Proteins; Longevity; p21-Activated Kinases; Phenylethyl Alcohol; Phenylpropionates; Protein Kinase Inhibitors; Recombinant Fusion Proteins; Reproduction; Signal Transduction

2013
Computational and experimental evidence of the anti-COVID-19 potential of honeybee propolis ingredients, caffeic acid phenethyl ester and artepillin c.
    Phytotherapy research : PTR, 2023, Volume: 37, Issue:9

    Topics: Animals; Bees; Caffeic Acids; Phenylethyl Alcohol; Propolis

2023