caffeic acid phenethyl ester has been researched along with allopurinol in 27 studies
| Studies (caffeic acid phenethyl ester) | Trials (caffeic acid phenethyl ester) | Recent Studies (post-2010) (caffeic acid phenethyl ester) | Studies (allopurinol) | Trials (allopurinol) | Recent Studies (post-2010) (allopurinol) |
|---|---|---|---|---|---|
| 840 | 1 | 469 | 15,096 | 743 | 3,363 |
| Protein | Taxonomy | caffeic acid phenethyl ester (IC50) | allopurinol (IC50) |
|---|---|---|---|
| Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | Rattus norvegicus (Norway rat) | 3.3765 | |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | 3.1861 | |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | 5.0758 | |
| Histamine H3 receptor | Cavia porcellus (domestic guinea pig) | 8.69 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 19 (70.37) | 29.6817 |
| 2010's | 6 (22.22) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Endo, Y; Hatayama, K; Hayashi, T; Nakano, H; Ohta, K; Sato, D; Sato, Y; Seki, C; Taguchi, R; Takahashi, T; Tokuraku, K; Uwai, K | 1 |
| Korshunova, GA; Mirzoeva, OK; Pushkareva, MA; Sud'ina, GF; Sumbatyan, NV; Varfolomeev, SD | 1 |
| Akyol, O; Irmak, MK; Karaman, A; Koltuksuz, U; Kutlu, NO; Ozyurt, H; Yağmurca, M | 1 |
| Akyol, O; Irmak, MK; Ozyurt, H; Söğüt, S | 1 |
| Longo, R; Russo, A; Vanella, A | 1 |
| Erdogan, H; Fadillioglu, E; Gozukara, ME; Gulec, M; Irmak, MK; Ozer, M; Sogut, S; Yagmurca, M | 1 |
| Chen, CN; Lin, JK; Wu, CL | 2 |
| Armutcu, F; Babucçu, O; Gürel, A; Hoşnuter, M; Işikdemir, A; Kargi, E | 1 |
| Acet, A; Ozer, MK; Parlakpinar, H | 1 |
| Akyol, O; Armutcu, F; Gurel, A; Ilhan, A; Iraz, M | 1 |
| Nishioka, N; Tsuji, T; Yoshizumi, K | 1 |
| Isik, B; Ozugurlu, F; Ozyurt, B; Ozyurt, H; Sahin, S; Sogut, S; Uz, E; Yilmaz, HR | 1 |
| Oktem, F; Ozgüner, F; Uz, E; Uzar, E; Yilmaz, HR | 1 |
| Akyol, O; Bagci, C; Gulec, M; Ince, H; Kandemir, E | 1 |
| Iraz, M; Koca, K; Ozyurt, B; Ozyurt, H; Sahin, S | 1 |
| Aslantas, O; Celik, S; Erdogan, S; Gorur, S; Hakverdi, S; Ocak, S | 1 |
| Altuğ, ME; Aslan, H; Bal, R; Duman, T; Ekici, F; Kontaş, T; Melek, IM; Serarslan, Y | 1 |
| Ciçek, E; Gökalp, O; Ozçelik, N; Ozer, MK; Uz, E; Yilmaz, HR | 1 |
| Cigremis, Y; Karaman, M; Kart, A; Ozen, H | 1 |
| Abdel-Naim, AB; Albukhari, AA; El-Beshbishy, HA; Gashlan, HM; Nagy, AA | 1 |
| Andiran, F; Haltas, H; Hirfanoglu, IM; Kosus, A; Tatli, MM; Tayman, C; Tonbul, A; Uysal, S | 1 |
| Akoglu, M; Bostanci, EB; Duzcan, SE; Kelten, EC; Sacar, M; Simsek, NG; Teke, Z; Yenisey, C | 1 |
| Akoglu, M; Bostanci, EB; Sacar, M; Simsek, NG; Teke, Z; Yenisey, C | 1 |
| Brusman, N; Choi, W; Gonzalez, N; Heppler, B; Hogle, E; Istre, H; Ma, L; Oñate, A; Oñate, S; Paula, S; Snider, L; Tucker, J; Villegas, V | 1 |
| Cai, M; Chen, S; Gao, X; Hu, H; Huang, L; Li, X; Liang, D; Liu, Y; Wu, Q; Xiao, C; Xie, Y; Yong, T | 1 |
27 other study(ies) available for caffeic acid phenethyl ester and allopurinol
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Structure-activity relations of rosmarinic acid derivatives for the amyloid β aggregation inhibition and antioxidant properties.
Topics: Amyloid beta-Peptides; Antioxidants; Cinnamates; Depsides; Dose-Response Relationship, Drug; Humans; Molecular Dynamics Simulation; Molecular Structure; Protein Aggregates; Rosmarinic Acid; Structure-Activity Relationship | 2017 |
Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties.
Topics: Antioxidants; Caffeic Acids; Hordeum; Humans; Kinetics; Linoleic Acid; Linoleic Acids; Lipoxygenase Inhibitors; Luminescent Measurements; Neutrophils; Oxidation-Reduction; Phenylethyl Alcohol; Reactive Oxygen Species; Xanthine; Xanthine Oxidase; Xanthines | 1993 |
The effect of caffeic acid phenethyl ester on ischemia-reperfusion injury in comparison with alpha-tocopherol in rat kidneys.
Topics: alpha-Tocopherol; Animals; Antioxidants; Caffeic Acids; Female; Kidney; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Xanthine Oxidase | 2001 |
Caffeic acid phenethyl ester changes the indices of oxidative stress in serum of rats with renal ischaemia-reperfusion injury.
Topics: Adenosine Deaminase; alpha-Tocopherol; Animals; Antioxidants; Caffeic Acids; Female; Kidney; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rats; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 2001 |
Antioxidant activity of propolis: role of caffeic acid phenethyl ester and galangin.
Topics: Antioxidants; Biphenyl Compounds; Caffeic Acids; Dose-Response Relationship, Drug; Flavonoids; Free Radical Scavengers; Humans; Lipid Peroxidation; Phenylethyl Alcohol; Phytotherapy; Picrates; Plant Extracts; Propolis; Xanthine Oxidase | 2002 |
Effects of caffeic acid phenethyl ester and alpha-tocopherol on reperfusion injury in rat brain.
Topics: Adenosine Deaminase; alpha-Tocopherol; Animals; Brain; Brain Chemistry; Caffeic Acids; Catalase; Data Interpretation, Statistical; Glutathione Peroxidase; Heart; Male; Malondialdehyde; Myocardium; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Statistics, Nonparametric; Superoxide Dismutase; Xanthine Oxidase | 2003 |
Propolin C from propolis induces apoptosis through activating caspases, Bid and cytochrome c release in human melanoma cells.
Topics: Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Caffeic Acids; Carrier Proteins; Caspases; Cell Cycle; Cell Division; Cell Survival; Cytochromes c; DNA Fragmentation; Enzyme Activation; Flavonoids; Free Radicals; Humans; Melanoma; Mitochondria; Phenylethyl Alcohol; Propolis; Xanthine Oxidase | 2004 |
The effect of CAPE on lipid peroxidation and nitric oxide levels in the plasma of rats following thermal injury.
Topics: Animals; Antioxidants; Burns; Caffeic Acids; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Xanthine Oxidase | 2004 |
Reduction of ischemia--reperfusion induced myocardial infarct size in rats by caffeic acid phenethyl ester (CAPE).
Topics: Animals; Antioxidants; Caffeic Acids; Free Radicals; Lipoxygenase; Male; Myocardial Infarction; Myocardium; Neutrophils; Oxidative Stress; Oxygen; Phenylethyl Alcohol; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Xanthine Oxidase | 2004 |
Caffeic acid phenethyl ester exerts a neuroprotective effect on CNS against pentylenetetrazol-induced seizures in mice.
Topics: Animals; Antioxidants; Biomarkers; Caffeic Acids; Central Nervous System; Convulsants; Female; Malondialdehyde; Mice; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Oxidants; Oxidative Stress; Pentylenetetrazole; Phenylethyl Alcohol; Reactive Oxygen Species; Seizures; Superoxide Dismutase; Xanthine Oxidase | 2004 |
[Xanthine oxidase inhibitory activity and hypouricemia effect of propolis in rats].
Topics: Animals; Anti-Infective Agents; Brazil; Caffeic Acids; China; Coumaric Acids; Disease Models, Animal; Flavonoids; Gout; Hyperuricemia; Male; Oxonic Acid; Phenylethyl Alcohol; Phenylpropionates; Propionates; Propolis; Rats; Rats, Sprague-Dawley; Uric Acid; Xanthine Oxidase | 2005 |
The activities of liver adenosine deaminase, xanthine oxidase, catalase, superoxide dismutase enzymes and the levels of malondialdehyde and nitric oxide after cisplatin toxicity in rats: protective effect of caffeic acid phenethyl ester.
Topics: Adenosine Deaminase; Animals; Antineoplastic Agents; Caffeic Acids; Catalase; Cisplatin; Liver; Malondialdehyde; Nitric Oxide; Phenylethyl Alcohol; Protective Agents; Rats; Superoxide Dismutase; Xanthine Oxidase | 2005 |
The activities of purine-catabolizing enzymes and the level of nitric oxide in rat kidneys subjected to methotrexate: protective effect of caffeic acid phenethyl ester.
Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Caffeic Acids; Folic Acid Antagonists; Free Radical Scavengers; Kidney; Male; Methotrexate; Nitric Oxide; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Xanthine Oxidase | 2005 |
Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis.
Topics: Apoptosis; Blotting, Western; Caffeic Acids; Caspase 3; Caspase 8; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Breaks; DNA Fragmentation; DNA, Circular; Dose-Response Relationship, Drug; Flavonoids; Flow Cytometry; HL-60 Cells; Humans; Melanoma; Mitochondria; Molecular Structure; Phenylethyl Alcohol; Propolis; Reactive Oxygen Species; Signal Transduction; Xanthine Oxidase | 2007 |
The effect of caffeic acid phenethyl ester on short-term acute myocardial ischemia.
Topics: Acute Disease; Adenosine Deaminase; Animals; Antioxidants; Caffeic Acids; Cardiotonic Agents; Catalase; Glutathione Peroxidase; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase; Xanthine Oxidase | 2006 |
Protective effects of caffeic acid phenethyl ester on skeletal muscle ischemia-reperfusion injury in rats.
Topics: Adenosine Deaminase; Animals; Caffeic Acids; Creatine Kinase; Male; Muscle, Skeletal; Peroxidase; Phenylethyl Alcohol; Protein Carbonylation; Rats; Rats, Wistar; Reperfusion Injury; Xanthine Oxidase | 2006 |
Caffeic acid phenethyl ester suppresses oxidative stress in Escherichia coli-induced pyelonephritis in rats.
Topics: Animals; Caffeic Acids; Catalase; Escherichia coli; Glutathione Peroxidase; Inflammation; Kidney; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Pyelonephritis; Rats; Rats, Wistar; Superoxide Dismutase; Xanthine Oxidase | 2007 |
Caffeic acid phenethyl ester protects rabbit brains against permanent focal ischemia by antioxidant action: a biochemical and planimetric study.
Topics: Animals; Antioxidants; Biomarkers; Brain Infarction; Brain Ischemia; Brain Mapping; Caffeic Acids; Catalase; Enzyme Inhibitors; Glutathione; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Lipid Peroxidation; Male; Malondialdehyde; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Rabbits; Spectrophotometry; Treatment Outcome; Xanthine Oxidase | 2008 |
Protective role of caffeic acid phenethyl ester and erdosteine on activities of purine-catabolizing enzymes and level of nitric oxide in red blood cells of isoniazid-administered rats.
Topics: Adenosine Deaminase; Administration, Oral; Animals; Antioxidants; Antitubercular Agents; Caffeic Acids; Disease Models, Animal; Drinking; Drug Therapy, Combination; Erythrocytes; Injections, Intraperitoneal; Isoniazid; Male; Nitric Oxide; Oxidative Stress; Phenylethyl Alcohol; Purines; Rats; Rats, Wistar; Thioglycolates; Thiophenes; Xanthine Oxidase | 2008 |
Caffeic acid phenethyl ester (CAPE) ameliorates cisplatin-induced hepatotoxicity in rabbit.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Caffeic Acids; Cisplatin; Glutathione; Liver; Male; Malondialdehyde; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Phenylethyl Alcohol; Rabbits; Xanthine Oxidase | 2010 |
Caffeic acid phenethyl ester protects against tamoxifen-induced hepatotoxicity in rats.
Topics: Animals; Antineoplastic Agents, Hormonal; Antioxidants; Caffeic Acids; Chemical and Drug Induced Liver Injury; Female; Glutathione; Lipid Peroxidation; Liver; Liver Function Tests; Neutrophils; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tamoxifen; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2009 |
Protective effects of caffeic acid phenethyl ester (CAPE) on intestinal damage in necrotizing enterocolitis.
Topics: Administration, Oral; Animals; Animals, Newborn; Apoptosis; Caffeic Acids; Caspase 9; Cell Count; Disease Models, Animal; Enterocolitis, Necrotizing; Ileum; Immunohistochemistry; In Situ Nick-End Labeling; NF-kappa B; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome; Xanthine Oxidase | 2011 |
Caffeic acid phenethyl ester prevents detrimental effects of remote ischemia-reperfusion injury on healing of colonic anastomoses.
Topics: Anastomosis, Surgical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeic Acids; Colon; Cytokines; Drug Evaluation, Preclinical; Hydroxyproline; Laparotomy; Male; Malondialdehyde; Mesenteric Artery, Superior; Oxidative Stress; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Surgical Wound Dehiscence; Wound Healing; Xanthine Oxidase | 2013 |
Caffeic acid phenethyl ester alleviates mesenteric ischemia/reperfusion injury.
Topics: Animals; Antioxidants; Caffeic Acids; Cytokines; Glutathione Peroxidase; Intestine, Small; Male; Malondialdehyde; Models, Animal; Nitrates; Oxidative Stress; Peroxidase; Phenylethyl Alcohol; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion Injury; Xanthine Oxidase | 2012 |
Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties.
Topics: Animals; Biphenyl Compounds; Caffeic Acids; Cattle; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Models, Molecular; Molecular Structure; Phenylethyl Alcohol; Picrates; Reactive Oxygen Species; Structure-Activity Relationship; Xanthine Oxidase | 2019 |
Caffeic acid phenethyl ester alleviated hypouricemia in hyperuricemic mice through inhibiting XOD and up-regulating OAT3.
Topics: Animals; Caffeic Acids; Hyperuricemia; Kidney; Mice; Molecular Docking Simulation; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Oxonic Acid; Phenylethyl Alcohol; RNA, Messenger; Uric Acid; Xanthine Oxidase | 2022 |