Page last updated: 2024-08-21

c 137 and nitracrine

c 137 has been researched along with nitracrine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, RF; Denny, WA; Thompson, LH; Wilson, WR1
Denny, WA; Ferguson, LR; Turner, PM1
Chorazy, M; Kalinowska, E1
Ciesielska, E; Szmigiero, L1
Denny, WA; Hicks, KO; Pullen, SM; Siim, BG; van Zijl, PL; Wilson, WR1
Baguley, BC; Hicks, KO; Pruijn, FB; Wilson, WR1
Fellner, S; Guenther, E; Kohler, K; Ladewig, T; Zrenner, E1
Bianchini, EP; Bock, PE; Krishnaswamy, S; Orcutt, SJ; Panizzi, P1

Other Studies

8 other study(ies) available for c 137 and nitracrine

ArticleYear
Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:1

    Topics: Aminoacridines; Animals; Cell Division; Cell Line; DNA; Nitracrine; Oxygen; Structure-Activity Relationship

1989
Mutagenicity of nitracrine analogues in Salmonella typhimurium: mutational specificity and activation by bacterial enzymes and rat-liver S9.
    Mutation research, 1987, Volume: 187, Issue:1

    Topics: Aminoacridines; Animals; Chemical Phenomena; Chemistry; Liver; Mutagenicity Tests; Mutagens; Nitracrine; Nitroreductases; Plasmids; Rats; Rats, Inbred Strains; Salmonella typhimurium

1987
Mutagenic activity of some 9-aminoalkyl acridine derivatives on S. typhimurium.
    Mutation research, 1980, Volume: 78, Issue:1

    Topics: Acridines; Aminoacridines; Drug Evaluation, Preclinical; Genetic Techniques; Mutagens; Nitracrine; Salmonella typhimurium

1980
Thiol dependent inhibition of mouse leukemia L1210 DNA topoisomerase I by nitracrine.
    Acta biochimica Polonica, 1994, Volume: 41, Issue:2

    Topics: Animals; Dithiothreitol; Drug Interactions; Leukemia L1210; Mice; Nitracrine; Topoisomerase I Inhibitors

1994
Comparison of aromatic and tertiary amine N-oxides of acridine DNA intercalators as bioreductive drugs. Cytotoxicity, DNA binding, cellular uptake, and metabolism.
    Biochemical pharmacology, 2000, Oct-01, Volume: 60, Issue:7

    Topics: Animals; Biological Transport; Cell Survival; Cells, Cultured; CHO Cells; Cricetinae; DNA; Intercalating Agents; Nitracrine

2000
Extravascular transport of the DNA intercalator and topoisomerase poison N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide (DACA): diffusion and metabolism in multicellular layers of tumor cells.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3

    Topics: Acridines; Animals; Antineoplastic Agents; Area Under Curve; Biological Transport; Body Fluid Compartments; Carbon Radioisotopes; Cell Line; Chromatography, High Pressure Liquid; Computer Simulation; Cricetinae; Diffusion; Diffusion Chambers, Culture; Drug Design; Fibroblasts; Intercalating Agents; Mammary Neoplasms, Experimental; Mice; Models, Biological; Nitracrine; Topoisomerase II Inhibitors; Urea

2001
BDNF regulates NMDA receptor activity in developing retinal ganglion cells.
    Neuroreport, 2004, Nov-15, Volume: 15, Issue:16

    Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Drug; Drug Interactions; Electric Capacitance; Heterozygote; In Vitro Techniques; Membrane Potentials; Mice; Mice, Knockout; N-Methylaspartate; Nitracrine; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells

2004
Ratcheting of the substrate from the zymogen to proteinase conformations directs the sequential cleavage of prothrombin by prothrombinase.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Jul-19, Volume: 102, Issue:29

    Topics: Binding Sites; Enzyme Activation; Enzyme Precursors; Fluorescence; Humans; Kinetics; Models, Molecular; Mutation; Nitracrine; Protein Conformation; Prothrombin; Structure-Activity Relationship; Substrate Specificity; Thrombin; Thromboplastin

2005