Compounds > c 1310
Page last updated: 2024-09-03

c 1310 and c 1311

c 1310 has been researched along with c 1311 in 6 studies

Compound Research Comparison

Studies
(c 1310)		Trials
(c 1310)		Recent Studies (post-2010)
(c 1310)		Studies
(c 1311)		Trials
(c 1311)		Recent Studies (post-2010) (c 1311)
60252123

Protein Interaction Comparison

ProteinTaxonomyc 1310 (IC50)c 1311 (IC50)
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.137

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cholody, WM; Konopa, J; Martelli, S1
Bryce, RA; Humphries, MP; Nolan, KA; Stratford, IJ1
Barnes, J; Bryce, RA; Dunstan, MS; Humphries, M; Leys, D; Nolan, KA; Stratford, IJ; Whitehead, RC1
Bączek, T; Koba, M1
Augustin, E; Konopa, J; Lamb, J; Wheatley, DN1
Bibby, MC; Burger, AM; Double, JA; Konopa, J1

Other Studies

6 other study(ies) available for c 1310 and c 1311

ArticleYear
Chromophore-modified antineoplastic imidazoacridinones. Synthesis and activity against murine leukemias.
    Journal of medicinal chemistry, 1992, Jan-24, Volume: 35, Issue:2

    Topics: Aminoacridines; Animals; Antineoplastic Agents; Imidazoles; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Male; Mice; Structure-Activity Relationship; Tumor Cells, Cultured

1992
Imidazoacridin-6-ones as novel inhibitors of the quinone oxidoreductase NQO2.
    Bioorganic & medicinal chemistry letters, 2010, May-01, Volume: 20, Issue:9

    Topics: Acridines; Acridones; Binding Sites; Catalytic Domain; Computer Simulation; Databases, Factual; Enzyme Inhibitors; Humans; Imidazoles; Quantitative Structure-Activity Relationship; Quinone Reductases; Thermodynamics

2010
Novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2): crystal structures, biochemical activity, and intracellular effects of imidazoacridin-6-ones.
    Journal of medicinal chemistry, 2011, Oct-13, Volume: 54, Issue:19

    Topics: Acridines; Cell Line, Tumor; Crystallography, X-Ray; Humans; Imidazoles; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Quinone Reductases; Structure-Activity Relationship

2011
Physicochemical interaction of antitumor acridinone derivatives with DNA in view of QSAR studies.
    Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2011, Volume: 20, Issue:8

    Topics:

2011
Imidazoacridinones arrest cell-cycle progression in the G2 phase of L1210 cells.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:1

    Topics: Aminoacridines; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Disease Models, Animal; Flow Cytometry; G2 Phase; Leukemia L1210; Mice; Mitosis; Mitotic Index; Tumor Cells, Cultured

1996
Preclinical evaluation of novel imidazoacridinone derivatives with potent activity against experimental colorectal cancer.
    British journal of cancer, 1996, Volume: 74, Issue:9

    Topics: Adenocarcinoma; Aminoacridines; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; DNA, Neoplasm; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred Strains; Mice, Nude; Neoplasms, Experimental; Time Factors; Transplantation, Heterologous

1996