Page last updated: 2024-08-23

bw-755c and thromboxane b2

bw-755c has been researched along with thromboxane b2 in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199020 (86.96)18.7374
1990's3 (13.04)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Holub, BJ; Thomas, LM1
Aramburo, MJ; Choi, JH; Hammerman, C1
Disa, J; Kowalska, MA; Rao, AK1
Aramburo, MJ; Hammerman, C; Hill, V1
Fitzgerald, MF; Parente, L; Whittle, BJ1
Bahrami, S; Mihm, F; Paul, E; Redl, H; Schlag, G1
Moncada, S; Salmon, JA; Tilling, LC1
Carey, F; Forder, RA1
Altman, R; Scazziota, A1
Eynard, A; Galli, G; Gregori, M; Maderna, P; Tremoli, E1
Boukili, MA; Bureau, M; Lagente, V; Lefort, J; Lellouch-Tubiana, A; Malanchère, E; Vargaftig, BB1
Dunkel, CG; Evers, AS; Needleman, P; Saffitz, JE1
Dallob, A; Herold, E; Humes, JL; Luell, S; Opas, EE1
Bahrami, S; Mihm, F; Redl, H; Schiesser, A; Schlag, G; Thurnher, M; Vogl, C1
Demediuk, P; Faden, AI; Lemke, M1
Cloutier, S; Jancar, S; Provençal, B; Sirois, P; Thériault, P1
Furman, BL; McKechnie, K; Parratt, JR1
Moncada, S; Salmon, JA; Simmons, PM1
Feduska, R; Lefer, AM; Roth, DM; Smith, JB1
Palmer, RM; Salmon, JA; Simmons, PM1
Boughton-Smith, NK; Hawkey, CJ; Whittle, BJ1
Mallarkey, G; Smith, GM1
Campbell, WB; Pfister, SL1

Other Studies

23 other study(ies) available for bw-755c and thromboxane b2

ArticleYear
Inhibition of phosphatidic acid production and lysophospholipid formation in collagen-stimulated human platelets by staurosporine, a protein kinase inhibitor.
    Cellular signalling, 1991, Volume: 3, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alkaloids; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Humans; Lysophospholipids; Phosphatidic Acids; Phospholipases A; Phospholipases A2; Prostaglandin Endoperoxides, Synthetic; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Stearic Acids; Thromboxane B2; Type C Phospholipases

1991
Prostanoid inhibition and group B hemolytic streptococci (GBS) induced neutropenia in newborn piglets.
    Prostaglandins, leukotrienes, and essential fatty acids, 1990, Volume: 41, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Animals, Newborn; Blood Pressure; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Imidazoles; Leukocyte Count; Lipoxygenase Inhibitors; Neutropenia; Neutrophils; Pulmonary Artery; Streptococcus agalactiae; Swine; Thromboxane B2; Vasoconstriction

1990
High concentrations of exogenous arachidonate inhibit calcium mobilization in platelets by stimulation of adenylate cyclase.
    The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenylyl Cyclases; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Calcium; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Enzyme Induction; Epoprostenol; Humans; Iloprost; In Vitro Techniques; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyrazoles; Thromboxane B2

1988
Lipoxygenase and cyclooxygenase blockade by BW755C does not prevent the secondary phase of septic pulmonary hypertension.
    Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 37, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase Inhibitors; Heart Rate; Hemodynamics; Hypertension, Pulmonary; Imidazoles; Lipoxygenase Inhibitors; Pyrazoles; Swine; Thromboxane B2; Thromboxane-A Synthase; Time Factors

1989
Release of PAF-acether and eicosanoids from guinea-pig alveolar macrophages by FMLP: effect of cyclo-oxygenase and lipoxygenase inhibition.
    European journal of pharmacology, 1989, May-30, Volume: 164, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Benzeneacetamides; Cyclooxygenase Inhibitors; Guinea Pigs; Hydroxamic Acids; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pulmonary Alveoli; Pyrazoles; Radioimmunoassay; Thromboxane B2

1989
Endotoxemia in rats--influence of lipoxygenase blocker versus leukotriene receptor antagonist (BW755C vs LY171883).
    Progress in clinical and biological research, 1988, Volume: 272

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Animals; Azoles; Endotoxins; Leukocyte Count; Lipoxygenase Inhibitors; Male; Platelet Count; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Leukotriene; Receptors, Prostaglandin; Tetrazoles; Thromboxane B2; Toxemia

1988
Evaluation of inhibitors of eicosanoid synthesis in leukocytes: possible pitfall of using the calcium ionophore A23187 to stimulate 5' lipoxygenase.
    Prostaglandins, 1985, Volume: 29, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonate Lipoxygenases; Calcimycin; Humans; Leukotriene B4; Lipoxygenase; Neutrophils; Propionates; Pyrazoles; Thromboxane B2; Zymosan

1985
Radioimmunoassay of LTB4 and 6-trans LTB4: analytical and pharmacological characterisation of immunoreactive LTB4 in ionophore stimulated human blood.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 22, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antibodies; Antibody Specificity; Calcimycin; Catechols; Chromatography, High Pressure Liquid; Cross Reactions; Dose-Response Relationship, Drug; Female; Humans; Leukotriene B4; Male; Masoprocol; Pyrazoles; Pyrazolones; Rabbits; Radioimmunoassay; Thromboxane B2; Time Factors

1986
Synergistic actions of paf-acether and sodium arachidonate in human platelet aggregation. 2. Unexpected results after aspirin intake.
    Thrombosis research, 1986, Jul-01, Volume: 43, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine; Administration, Oral; Adult; Apyrase; Arachidonic Acids; Aspirin; Catechols; Drug Synergism; Epoprostenol; Humans; Indomethacin; Masoprocol; Platelet Activating Factor; Platelet Aggregation; Pyrazoles; Thromboxane B2; Time Factors; Umbelliferones

1986
In vitro effects of aspirin and non steroidal anti-inflammatory drugs on the formation of 12-hydroxyeicosatetraenoic acid by platelets.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:2-3

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Collagen; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase; Platelet Aggregation; Pyrazoles; Sodium Salicylate; Thromboxane B2

1986
Pharmacological modulation of the effects of N-formyl-L-methionyl-L-leucyl-L-phenylalanine in guinea-pigs: involvement of the arachidonic acid cascade.
    British journal of pharmacology, 1986, Volume: 89, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Cell Count; Blood Platelets; Bronchi; Female; Guinea Pigs; Indomethacin; Lung; Male; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Pyrazoles; Thromboxane B2

1986
Exaggerated atrial arachidonate metabolism in rabbit left ventricular myocardial infarction.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Coronary Circulation; Coronary Vessels; Heart Atria; Indomethacin; Kinetics; Myocardial Infarction; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandins; Pyrazoles; Rabbits; SRS-A; Thromboxane B2; Vasoconstriction

1987
Pharmacological modulation of eicosanoid levels and hyperalgesia in yeast-induced inflammation.
    Biochemical pharmacology, 1987, Feb-15, Volume: 36, Issue:4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate 5-Lipoxygenase; Dinoprostone; Edema; Eicosanoic Acids; Hyperalgesia; Hyperesthesia; Mycoses; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Pyrazoles; Rats; Saccharomyces cerevisiae; Thromboxane B2

1987
Effect of the nonsteroidal antiinflammatory agent BW755C in rat and sheep endotoxemia.
    Progress in clinical and biological research, 1987, Volume: 236A

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Capillary Permeability; Endotoxins; Escherichia coli; Hemodynamics; Leukocyte Count; Lymph; Male; Platelet Count; Pyrazoles; Rats; Rats, Inbred Strains; Sheep; Shock, Septic; Thromboxane B2

1987
Effects of BW755C, a mixed cyclo-oxygenase-lipoxygenase inhibitor, following traumatic spinal cord injury in rats.
    Brain research, 1988, Oct-25, Volume: 463, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Enzyme Inhibitors; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Strains; Spinal Cord Injuries; Thromboxane B2

1988
Mechanism of action of platelet-activating factor on guinea-pig lung parenchyma strips.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:9

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Guinea Pigs; Immunoenzyme Techniques; Lung; Masoprocol; Methacrylates; Muscle Contraction; Platelet Activating Factor; Pyrazoles; Sulfonamides; Thromboxane A2; Thromboxane B2

1988
Metabolic and cardiovascular effects of endotoxin infusion in conscious unrestrained rats: effects of methylprednisolone and BW755C.
    Circulatory shock, 1985, Volume: 15, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Antimetabolites; Arachidonic Acids; Blood Pressure; Heart Rate; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Pyrazoles; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2

1985
The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Dexamethasone; Dinoprostone; Exudates and Transudates; Fatty Acids, Unsaturated; Indomethacin; Inflammation; Leukocyte Count; Leukocytes; Leukotriene B4; Male; Prostaglandins E; Pyrazoles; Rats; Thromboxane B2

1983
Effects of lipoxygenase inhibitors in arachidonate-induced sudden death.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Cathepsin D; Cathepsins; Death, Sudden; Glucuronidase; Lipoxygenase Inhibitors; Liver; Lung; Lysosomes; Male; Masoprocol; Pancreas; Pyrazoles; Rabbits; Thromboxane B2

1984
Release of leukotriene B4 from human neutrophils measured by specific radioimmunoassay.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 11

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Calcimycin; Cytochalasin B; Dinoprostone; Humans; Indomethacin; Kinetics; Leukotriene B4; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Prostaglandins E; Pyrazoles; Radioimmunoassay; Thromboxane B2

1983
Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa.
    Gut, 1983, Volume: 24, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colitis, Ulcerative; Colon; Humans; Indomethacin; Intestinal Mucosa; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Thromboxane B2

1983
The effect of arachidonic acid metabolism on intravascular platelet aggregation in rats.
    Thrombosis research, 1984, Oct-15, Volume: 36, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chromatography, Thin Layer; Collagen; Indomethacin; Piroxicam; Platelet Aggregation; Propionates; Pyrazoles; Radioimmunoassay; Rats; Thiazines; Thromboxane B2

1984
Role of endothelium-derived metabolites of arachidonic acid in enhanced pulmonary artery contractions in female rabbits.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Methacholine Chloride; Potassium Chloride; Pulmonary Artery; Rabbits; Sex Characteristics; Thromboxane B2; Vasoconstriction

1996