Page last updated: 2024-08-23

bw-755c and masoprocol

bw-755c has been researched along with masoprocol in 100 studies

Research

Studies (100)

Timeframe	Studies, this research(%)	All Research%
pre-1990	75 (75.00)	18.7374
1990's	25 (25.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bélanger, PC; Denis, D; Dufresne, C; Fitzsimmons, B; Ford-Hutchinson, AW; Lau, CK; Riendeau, D; Scheigetz, J; Therien, M; Young, RN	1
Kreft, AF; Musser, JH	1
Bruneau, P; Delvare, C; Edwards, MP; McMillan, RM	1
Bell, RL; Brooks, DW; Carter, GW; Dyer, RD; Holms, JH; Kerdesky, FA; Moore, JL	1
Gueremy, G; Malleron, JL; Ponsinet, G; Robin, JL; Roussel, G; Terlain, B; Tissieres, JM	1
Bermudez, J; Buckle, DR; Foster, KA; Markwell, RE; Smith, SA; Taylor, JF; Tedder, JM; Thody, VE; Webster, RA	1
Carter, GW; Dyer, RD; Holms, JH; Mazdiyasni, H; Ratajczyk, JD; Summers, JB	1
Brass, LF; Woolkalis, MJ	1
Choi, MS; Cooke, BA; Lopez-Ruiz, MP; Rose, MP; West, AP	1
Baba, T; Black, KL; Chio, CC	1
Braquet, P; Lagente, V; Mencia-Huerta, JM; Pons, F; Touvay, C	1
Ebbesen, MA; Gibel, L; Goodwin, JS; Harford, AM; Shopp, GM; Smith, AY; Sterling, WA	1
Bedwell, S; Darley-Usmar, V; Jessup, W; O'Leary, V	1
Campbell, WB; Falck, JR; Pfister, SL	1
Buller, RM; Palumbo, GJ	1
Calixto, JB; Cruz, AB; Medeiros, YS; Yunes, RA; Zanini Júnior, JC	1
Becherucci, C; Mugridge, KG; Parente, L; Perretti, M	1
Aréjola, JM; Guarner, F; Prieto, J; Quiroga, J; Rodríguez Ortigosa, C; Rodríguez-Sanromán, JL	1
Espey, LL; Kawano, T; Okamura, H; Tanaka, N	1
Dikshit, M; Srimal, RC	1
Ardaillou, R; Bens, M; Guidet, B; Lacave, R; Nagamine, Y; Rondeau, E; Sraer, J; Sraer, JD	1
Alonso, MT; Garcia-Sancho, J; Sanchez, A	1
Conroy, MC; Kennedy, JA; Thueson, DO	1
Boctor, AM; Pugsley, TA	1
Chand, N; Diamantis, W; Pillar, J; Sofia, RD	1
Behrens, TW; Goodwin, JS; Lianos, EA; Lum, LG	1
Azizova, OA; Borin, ML; Ivanova, MA; Khodorov, BI; Markov, CM; Pinelis, VG	1
Metz, SA	2
Farnam, J; Giclas, PC; Grant, JA; Hunt, C; Lett-Brown, MA; Thueson, DO	1
Adkinson, NF; Gottlieb, JE; McGeady, M; Sylvester, JT	1
Iizuka, T; Ishimura, Y; Kanegasaki, S; Makino, R; Tanaka, T	1
Dejana, E; Prosdocimi, M; Zanetti, A; Zatta, A	1
Canonico, PL; Judd, AM; Koike, K; MacLeod, RM; Valdenegro, CA	1
Kato, R; Nakadate, T; Uzumaki, H; Yamamoto, S	1
Jondal, M; Kullman, C; Lindgren, JA; Rossi, P	1
Demharter, R; Gärtner, R; Greil, W; Horn, K	1
Catt, KJ; Kiesel, L; Naor, Z; Vanderhoek, JY	1
Ishitoya, J; Nagai, Y; Takenawa, T	1
Beetens, JR; Coene, MC; De Clerck, F; Loots, W; Somers, Y	1
Carey, F; Forder, RA	1
Dreyling, KW; Hoppe, U; Kozuschek, W; Morgenroth, K; Peskar, BA; Peskar, BM	1
Bankhurst, AD; Imir, T; Sibbitt, WL	1
Roth, JA; Webb, DS	1
Hand, JM; Lewis, AJ; Schwalm, SF	2
Ishiura, S; Villee, CA; Yoshimoto, T	1
Altman, R; Scazziota, A	1
Miller, AM; Weiner, RS; Ziboh, VA	1
Coupar, IM; Stanton, BJ	1
Kishore, NP; Rao, GH; White, JG	1
Edwards, RH; Jackson, MJ; Wagenmakers, AJ	1
Beckman, BS; Fisher, JW; King, L; Mason-Garcia, M; Nystuen, L	1
Bertrand, C; Frossard, N; Landry, Y; Tschirhart, E	1
Kato, R; Kiyoto, I; Nakadate, T; Sasakawa, N; Yamamoto, S	1
Barton, BE; Wheeler, L; WoldeMussie, E	1
Acker, G; Braquet, P; Etienne, A; Hecquet, F; Mencia-Huerta, JM	1
Beckman, B; Nystuen, L	1
Goldin, E; Harel, S; Magal, E; Yavin, E	1
Anderson, GP; Fennessy, MR; White, HL	1
Reynolds, CH	1
Carey, F; Edmonds, AE; Forder, RA; Haworth, D	1
Cloutier, S; Jancar, S; Provençal, B; Sirois, P; Thériault, P	1
Hiley, CR; Kay, AP; Randall, MD	1
Emeis, JJ; Havekes, L; van der Schroeff, JG; Vermeer, BJ; Weerheim, AM	1
Zawalich, K; Zawalich, W	1
Fleetwood, GG; Letts, LG; Poole-Wilson, PA; Tones, MA	1
Colca, J; Comens, PG; Jakschik, B; McDaniel, ML; Turk, J; Wolf, BA	1
Förstermann, U; Neufang, B	1
Burka, JF	1
Cammarata, P; Pincus, SH	1
Allix, M; Boulu, RG; Capdeville, C; el Bouchi, N; Fradin, A; Plotkine, M; Russo-Marie, F	1
Austen, KF; Schick, B	1
Bird, J; Giroud, JP	1
Bird, J; Giroud, JP; Tissot, M	1
Johnson, KJ; Sulavik, MC; Ward, PA	1
Colotta, F; de Gaetano, G; Semeraro, N; Villa, S	1
Knepel, W; Vlaskovska, M	1
Kulkarni, PS; Srinivason, BD	1
Feduska, R; Lefer, AM; Roth, DM; Smith, JB	1
Dawson, W; Kitchen, EA	1
Armour, CL; Hughes, JM; Seale, JP; Temple, DM	1
Fujimoto, WY; Metz, SA; Robertson, RP	2
Clanton, JA; Colley, DG; Rand, TH	1
Boughton-Smith, NK; Whittle, BJ	1
Harvey, J; Osborne, DJ	1
Seaman, WE	1
Goossens, J; Van Wauwe, J	1
Borgeat, P; Braquet, P; Salari, H	1
Canonico, PL; Judd, AM; MacLeod, RM; Valdenegro, CA	1
Cooke, BA; Dix, CJ; Habberfield, AD; Sullivan, MH	1
Chang, J; Cherney, ML; Lewis, AJ; Skowronek, MD	1
Seaman, WE; Woodcock, J	1
Kohen, F; Naor, Z; Reich, R; Tsafriri, A	1
Becker, K; Förster, W; Grupe, R; Lueddeckens, G	1
Denizot, Y; Najid, A; Rigaud, M	1
Ayyub Khan, M; Hoffbrand, AV; Tateson, JE; Wickremasinghe, RG	1
Campbell, WB; Pfister, SL	1
Conzen, J; Grimminger, F; Kiss, L; Seeger, W; Weissmann, N	1

Reviews

1 review(s) available for bw-755c and masoprocol

Article	Year
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors. Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14 Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines	1992

Other Studies

99 other study(ies) available for bw-755c and masoprocol

Article	Year
Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase. Journal of medicinal chemistry, 1992, Apr-03, Volume: 35, Issue:7 Topics: Animals; Arachidonate 5-Lipoxygenase; Benzofurans; Biological Availability; Bronchoconstriction; Dogs; Humans; Leukocytes, Mononuclear; Leukotriene B4; Lipoxygenase Inhibitors; Male; Methemoglobin; Microsomes, Liver; Molecular Structure; Rats; Rats, Inbred Strains; Saimiri; Structure-Activity Relationship	1992
Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: Administration, Oral; Animals; Chemical Phenomena; Chemistry; Dinoprostone; Dogs; Humans; Indazoles; Leukotriene B4; Lipoxygenase Inhibitors; Male; Methemoglobinemia; Methylation; Molecular Structure; Oxidation-Reduction; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2	1991
4-hydroxythiazole inhibitors of 5-lipoxygenase. Journal of medicinal chemistry, 1991, Volume: 34, Issue:7 Topics: Animals; Arachidonate 5-Lipoxygenase; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Humans; Lipoxygenase Inhibitors; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazoles	1991
Penta- and hexadienoic acid derivatives: a novel series of 5-lipoxygenase inhibitors. Journal of medicinal chemistry, 1990, Volume: 33, Issue:10 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Assay; Dose-Response Relationship, Drug; Edema; Fatty Acids, Unsaturated; Lipoxygenase Inhibitors; Mice; Sorbic Acid; Structure-Activity Relationship	1990
Novel 1H-benzimidazol-4-ols with potent 5-lipoxygenase inhibitory activity. Journal of medicinal chemistry, 1987, Volume: 30, Issue:12 Topics: Animals; Arachidonate Lipoxygenases; Benzimidazoles; Female; Lipoxygenase Inhibitors; Rats; Rats, Inbred Strains; SRS-A; Structure-Activity Relationship	1987
Hydroxamic acid inhibitors of 5-lipoxygenase. Journal of medicinal chemistry, 1987, Volume: 30, Issue:3 Topics: Arachidonate Lipoxygenases; Cell Line; Hydroxamic Acids; Kinetics; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Molecular Conformation; Protein Binding; Structure-Activity Relationship	1987
Dual regulation of cyclic AMP formation by thrombin in HEL cells, a leukaemic cell line with megakaryocytic properties. The Biochemical journal, 1992, Jan-01, Volume: 281 ( Pt 1) Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenylate Cyclase Toxin; Calcium; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Cytosol; Epinephrine; Epoprostenol; Humans; Inositol Phosphates; Kinetics; Leukemia; Masoprocol; Megakaryocytes; Pertussis Toxin; Thrombin; Trypsin; Virulence Factors, Bordetella	1992
Direct effect of arachidonic acid on protein kinase C and LH-stimulated steroidogenesis in rat Leydig cells; evidence for tonic inhibitory control of steroidogenesis by protein kinase C. Endocrinology, 1992, Volume: 130, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acids; Bucladesine; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Leydig Cells; Luteinizing Hormone; Male; Masoprocol; Protein Kinase C; Rats; Rats, Inbred Strains; Testosterone; Time Factors	1992
The effect of 5-lipoxygenase inhibition on blood-brain barrier permeability in experimental brain tumors. Journal of neurosurgery, 1992, Volume: 77, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Analysis of Variance; Animals; Autoradiography; Benzoquinones; Blood-Brain Barrier; Brain Neoplasms; Carcinoma 256, Walker; Female; gamma-Glutamyltransferase; Leukotrienes; Lipoxygenase Inhibitors; Masoprocol; Rats; Rats, Inbred Strains	1992
Comparison of the effects of intra-arterial and aerosol administration of endothelin-1 (ET-1) in the guinea-pig isolated lung. British journal of pharmacology, 1991, Volume: 102, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Aerosols; Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Endothelins; Guinea Pigs; Histamine Release; In Vitro Techniques; Indomethacin; Injections, Intra-Arterial; Lung; Male; Masoprocol; Perfusion; Respiratory Function Tests; SRS-A; Thromboxane A2	1991
Murine thymocyte lysis by inhibitors of arachidonic acid metabolism. Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21B Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenal Cortex Hormones; Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Caffeic Acids; Cells, Cultured; Dexamethasone; Dinoprostone; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred C57BL; Spleen; Thymus Gland	1991
5-Lipoxygenase is not essential in macrophage-mediated oxidation of low-density lipoprotein. The Biochemical journal, 1991, Aug-15, Volume: 278 ( Pt 1) Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Benzeneacetamides; Butylated Hydroxytoluene; Cells, Cultured; Endocytosis; Free Radical Scavengers; Humans; Hydroxamic Acids; Indoles; Lipoproteins, LDL; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Oxidation-Reduction	1991
Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta. The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 2 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; 8,11,14-Eicosatrienoic Acid; Animals; Aorta, Thoracic; Arachidonic Acids; Carbon Radioisotopes; Cholesterol, Dietary; Clotrimazole; Diet, Atherogenic; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Kinetics; Masoprocol; Metyrapone; Muscle, Smooth, Vascular; Rabbits; Reference Values; Stereoisomerism	1991
Inhibitors of the lipoxygenase pathway specifically block orthopoxvirus replication. Virology, 1991, Volume: 180, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Cells, Cultured; Chick Embryo; Cowpox virus; Ectromelia virus; Electrophoresis, Polyacrylamide Gel; Lipoxygenase Inhibitors; Masoprocol; Vaccinia virus; Viral Proteins; Virus Replication	1991
Extract and compounds obtained from Mandevilla velutina inhibit arachidonic acid-induced ear oedema in mice, but not rat stomach contraction. Prostaglandins, 1991, Volume: 41, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Edema; Female; In Vitro Techniques; Indomethacin; Isometric Contraction; Lipoxygenase Inhibitors; Male; Masoprocol; Mice; Muscle, Smooth; Plant Extracts; Pyrazoles; Rats; Stomach	1991
Evidence that interleukin-1 and lipoxygenase metabolites mediate the lethal effect of complete Freund's adjuvant in adrenalectomized rats. Lymphokine and cytokine research, 1991, Volume: 10, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adjuvants, Immunologic; Adrenalectomy; Animals; Aspirin; Dexamethasone; Indomethacin; Interleukin-1; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Peritoneal Cavity; Rats; Rats, Inbred Strains; Recombinant Proteins	1991
Inhibitors of the lipoxygenase arachidonic acid pathway impair glycocholate efflux in isolated rat hepatocytes. Journal of hepatology, 1991, Volume: 12, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Cell Survival; Glycocholic Acid; In Vitro Techniques; Lipoxygenase Inhibitors; Liver; Male; Masoprocol; Oxygen Consumption; Rats; Rats, Inbred Strains	1991
Comparison of inhibitory actions of indomethacin and epostane on ovulation in rats. The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 17-alpha-Hydroxyprogesterone; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Androstenedione; Androstenols; Animals; Chorionic Gonadotropin; Estradiol; Female; Hydroxyeicosatetraenoic Acids; Hydroxyprogesterones; Indomethacin; Masoprocol; Ovulation; Ovulation Induction; Progesterone; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Steroids; Testosterone	1991
Evidence for the presence of a new plasma factor which acts synergistically to ADP induced platelet aggregation. Life sciences, 1990, Volume: 47, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Animals; Biological Factors; Cimetidine; Drug Synergism; Enzymes; Epoprostenol; Heparin; Indomethacin; Ketanserin; Macaca mulatta; Male; Masoprocol; Mice; Mice, Inbred Strains; Phentolamine; Platelet Aggregation	1990
Nordihydroguaiaretic acid inhibits urokinase synthesis by phorbol myristate acetate-stimulated LLC-PK1 cells. Biochimica et biophysica acta, 1990, Nov-12, Volume: 1055, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Cell Line; Enzyme Precursors; Fatty Acids, Unsaturated; Isoquinolines; Kinetics; Masoprocol; Piperazines; Plasminogen Activators; Plasminogen Inactivators; Protein Kinase C; Pyrazoles; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator	1990
Arachidonic acid-induced calcium influx in human platelets. Comparison with the effect of thrombin. The Biochemical journal, 1990, Dec-01, Volume: 272, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Biological Transport; Blood Platelets; Calcium; Carcinoma, Ehrlich Tumor; Egtazic Acid; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Fluoresceins; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; Kinetics; Manganese; Masoprocol; Mice; Neutrophils; Prostaglandin Endoperoxides, Synthetic; Rats; Spectrometry, Fluorescence; Structure-Activity Relationship; T-Lymphocytes; Thrombin	1990
Differential inhibition of histamine release from human basophils induced by antigen, anti-IgE or N-formyl-L-methionyl-L-leucyl-L-phenylalanine. International archives of allergy and applied immunology, 1985, Volume: 77, Issue:1-2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Antibodies, Anti-Idiotypic; Antigens; Basophils; Catechols; Cells, Cultured; Chromones; Histamine Release; Humans; Immunoglobulin E; Indoles; Indomethacin; Masoprocol; Meclofenamic Acid; N-Formylmethionine Leucyl-Phenylalanine; Oxazoles; Pyrazoles; Receptors, Fc; Receptors, Formyl Peptide; Receptors, IgE; Receptors, Immunologic; Tetrazoles	1985
Effect of CI-922, a potential new antiallergy agent, on arachidonic acid metabolism in vitro. Inflammation, 1986, Volume: 10, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adult; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Azoles; Calcimycin; Cattle; Histamine Release; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indoles; Indomethacin; Leukocytes; Male; Masoprocol; Pyrazoles; Seminal Vesicles; Tetrazoles	1986
Modulation of allergic and nonallergic histamine secretion by lipoxygenase inhibitors. Research communications in chemical pathology and pharmacology, 1987, Volume: 55, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Catechols; Fatty Acids, Unsaturated; Histamine Release; Hypersensitivity; Kinetics; Lipoxygenase Inhibitors; Masoprocol; Mast Cells; Pyrazoles; Rabbits; Rats; Rats, Inbred Strains	1987
Lipoxygenase inhibitors enhance the proliferation of human B cells. Journal of immunology (Baltimore, Md. : 1950), 1989, Oct-01, Volume: 143, Issue:7 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adjuvants, Immunologic; Adult; B-Lymphocytes; Benzoquinones; Cell Differentiation; Child; Cyclooxygenase Inhibitors; Dose-Response Relationship, Immunologic; Humans; Immunoglobulins; Indomethacin; Interleukin-4; Interleukins; Kinetics; Lipoxygenase Inhibitors; Lymphocyte Activation; Masoprocol; Palatine Tonsil; Pyrazoles; Quinones; Staphylococcal Protein A	1989
Blockade of ADP-induced Ca2+-signal and platelet aggregation by lipoxygenase inhibitors. FEBS letters, 1989, Nov-06, Volume: 257, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Calcium; Humans; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Platelet Aggregation; Platelet Aggregation Inhibitors; Signal Transduction	1989
Blockade by lipoxygenase inhibitors of Ca2+-dependent insulin secretion from permeabilized rat islets. A molecular mechanism distinct from that of alpha 2-adrenergic agonists. Biochemical pharmacology, 1989, Jun-01, Volume: 38, Issue:11 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenergic alpha-Antagonists; Calcium; Cell Membrane Permeability; Hydroxyeicosatetraenoic Acids; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase; Lipoxygenase Inhibitors; Magnesium; Masoprocol; Pyrazoles; Secretory Rate; Tetradecanoylphorbol Acetate	1989
Complement- and IgE-mediated release of histamine from basophils in vitro. V. Differential effects of drugs modulating arachidonic acid metabolism. Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 134, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Basophils; Catechols; Complement C5; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Masoprocol; Phospholipases; Pyrazoles	1985
Effects of cyclo- and lipoxygenase inhibitors on hypoxic vasoconstriction in isolated ferret lungs. Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Gas Analysis; Blood Pressure; Catechols; Cyclooxygenase Inhibitors; Dinoprost; Ferrets; Hydrogen-Ion Concentration; Hypoxia; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Organ Culture Techniques; Oxygen; Potassium Chloride; Prostaglandins F; Pyrazoles; Vasoconstriction	1988
Activation by saturated and monounsaturated fatty acids of the O2- -generating system in a cell-free preparation from neutrophils. The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Membrane; Cell-Free System; Cytosol; Fatty Acids; Fatty Acids, Unsaturated; Kinetics; Lauric Acids; Lipoxygenase Inhibitors; Masoprocol; NADP; Neutrophils; Oleic Acid; Oleic Acids; Oxygen Consumption; Pyrazoles; Superoxides; Swine; Tetradecanoylphorbol Acetate	1988
The effect of AD6 (8-monochloro-3-beta-diethylamino-ethyl-4-methyl-7-ethoxy- carbonylmethoxycoumarin) on washed human platelet aggregation induced by platelet activating factor (PAF) and epinephrine. European journal of pharmacology, 1986, Aug-22, Volume: 128, Issue:1-2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Aspirin; beta-Thromboglobulin; Blood Platelets; Chromonar; Coumarins; Drug Interactions; Epinephrine; Humans; In Vitro Techniques; Masoprocol; Platelet Activating Factor; Platelet Aggregation; Pyrazoles	1986
Arachidonate stimulates prolactin release in vitro: a role for the fatty acid and its metabolites as intracellular regulator(s) in mammotrophs. Endocrinology, 1985, Volume: 116, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Catechols; Cells, Cultured; Female; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Oleic Acid; Oleic Acids; Phospholipases A; Phospholipases A2; Pituitary Gland; Pituitary Gland, Anterior; Prolactin; Pyrazoles; Quinacrine; Rats; Rats, Inbred Strains; Stearic Acids; Tetradecanoylphorbol Acetate	1985
Lipoxygenase inhibitors and cyclic AMP-mediated insulin secretion caused by forskolin, theophylline and dibutyryl cyclic AMP. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Bucladesine; Catechols; Colforsin; Cyclic AMP; Diterpenes; Indomethacin; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Lipoxygenase Inhibitors; Male; Masoprocol; Pyrazoles; Rats; Secretory Rate; Theophylline	1985
Second messenger function of arachidonic acid lipoxygenation products in human natural killer cell lysis? Scandinavian journal of immunology, 1985, Volume: 22, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Catechols; Cyclic AMP; Cyclic GMP; Cytotoxicity, Immunologic; Humans; Indomethacin; Killer Cells, Natural; Lipoxygenase; Masoprocol; Pyrazoles	1985
Involvement of cyclic AMP, iodide and metabolites of arachidonic acid in the regulation of cell proliferation of isolated porcine thyroid follicles. Molecular and cellular endocrinology, 1985, Volume: 42, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Cell Division; Colforsin; Culture Media; Culture Techniques; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Epidermal Growth Factor; Indomethacin; Insulin; Iodides; Masoprocol; Propylthiouracil; Pyrazoles; Swine; Thyroid Gland; Thyrotropin	1985
Mechanism of action of gonadotropin releasing hormone: role of lipoxygenase products of arachidonic acid in luteinizing hormone release. Journal of steroid biochemistry, 1985, Volume: 23, Issue:5B Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catechols; Cells, Cultured; Gonadotropin-Releasing Hormone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Luteinizing Hormone; Masoprocol; Pituitary Gland; Pyrazoles; Rats; SRS-A	1985
Inhibitory effect of prostaglandin E2, forskolin, and dibutyryl cAMP on arachidonic acid release and inositol phospholipid metabolism in guinea pig neutrophils. The Journal of biological chemistry, 1986, Jan-25, Volume: 261, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Catechols; Colforsin; Dinoprostone; Fatty Acids, Nonesterified; Guinea Pigs; Lysosomes; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Prostaglandins E; Pyrazoles; Superoxides	1986
Ketoconazole inhibits the biosynthesis of leukotrienes in vitro and in vivo. Biochemical pharmacology, 1986, Mar-15, Volume: 35, Issue:6 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bronchi; Catechols; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Ketoconazole; Leukotriene B4; Lipoxygenase Inhibitors; Male; Masoprocol; Neutrophils; Pyrazoles; Rabbits; Rats; Rats, Inbred Strains; Reticulocytes; SRS-A	1986
Radioimmunoassay of LTB4 and 6-trans LTB4: analytical and pharmacological characterisation of immunoreactive LTB4 in ionophore stimulated human blood. Prostaglandins, leukotrienes, and medicine, 1986, Volume: 22, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antibodies; Antibody Specificity; Calcimycin; Catechols; Chromatography, High Pressure Liquid; Cross Reactions; Dose-Response Relationship, Drug; Female; Humans; Leukotriene B4; Male; Masoprocol; Pyrazoles; Pyrazolones; Rabbits; Radioimmunoassay; Thromboxane B2; Time Factors	1986
Leukotriene synthesis by human gastrointestinal tissues. Biochimica et biophysica acta, 1986, Sep-12, Volume: 878, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenocarcinoma; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Colonic Neoplasms; Digestive System; Dinoprostone; Gastric Mucosa; Humans; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Masoprocol; Muscle, Smooth; Prostaglandins E; Pyrazoles; SRS-A	1986
Reversible inhibition of lymphokine-activated killer cell activity by lipoxygenase-pathway inhibitors. International journal of cancer, 1986, Oct-15, Volume: 38, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Centrifugation, Density Gradient; Chromium; Cytotoxicity, Immunologic; Humans; Interleukin-2; Killer Cells, Natural; Leukotriene B4; Lipoxygenase Inhibitors; Lymphokines; Masoprocol; Pyrazoles	1986
Relationship of glucocorticoid suppression of arachidonic acid metabolism to alteration of neutrophil function. Journal of leukocyte biology, 1987, Volume: 41, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Dexamethasone; Diglycerides; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotriene B4; Masoprocol; Neutrophils; Phospholipids; Pyrazoles; Triglycerides; Zymosan	1987
Antagonism of antigen-induced contraction of isolated guinea-pig trachea by 5-lipoxygenase inhibitors. International archives of allergy and applied immunology, 1986, Volume: 79, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Catechols; Chlorpheniramine; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrazoles; SRS-A; Trachea	1986
Reticulocyte lipoxygenase, ingensin, and ATP-dependent proteolysis. FEBS letters, 1986, May-26, Volume: 201, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Adenosine Triphosphate; Animals; Caseins; Catechols; Chromatography, High Pressure Liquid; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme Activation; Hemin; Isoelectric Point; Linoleic Acid; Linoleic Acids; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Multienzyme Complexes; Peptide Hydrolases; Phenanthrolines; Proteasome Endopeptidase Complex; Pyrazoles; Rabbits; Reticulocytes; Salicylamides	1986
Synergistic actions of paf-acether and sodium arachidonate in human platelet aggregation. 2. Unexpected results after aspirin intake. Thrombosis research, 1986, Jul-01, Volume: 43, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine; Administration, Oral; Adult; Apyrase; Arachidonic Acids; Aspirin; Catechols; Drug Synergism; Epoprostenol; Humans; Indomethacin; Masoprocol; Platelet Activating Factor; Platelet Aggregation; Pyrazoles; Thromboxane B2; Time Factors; Umbelliferones	1986
Evidence for the role of leukotrienes C4 and D4 as essential intermediates in CSF-stimulated human myeloid colony formation. Experimental hematology, 1986, Volume: 14, Issue:8 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Bone Marrow Cells; Catechols; Colony-Forming Units Assay; Colony-Stimulating Factors; Granulocytes; Hematopoiesis; Humans; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Pyrazoles; SRS-A	1986
The effect of BW 755C and nordihydroguaiaretic acid in the rat isolated perfused mesenteric vasculature. Prostaglandins, leukotrienes, and medicine, 1986, Volume: 25, Issue:2-3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Calcium; Catechols; In Vitro Techniques; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Mesenteric Arteries; Mesenteric Veins; Norepinephrine; Pyrazoles; Rats; Rats, Inbred Strains	1986
Lipoxygenase inhibitors reduce insulin secretion without impairing calcium mobilization. Endocrinology, 1987, Volume: 120, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antimycin A; Arachidonate Lipoxygenases; Barium; Butylated Hydroxytoluene; Calcium; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Gallic Acid; Insulin; Insulin Secretion; Lipoxygenase Inhibitors; Male; Masoprocol; Phospholipases A; Potassium; Pyrazoles; Rats; Secretory Rate; Trifluoperazine	1987
Differential effects of putative inhibitors on cytosolic and membrane associated platelet lipoxygenase. Prostaglandins, leukotrienes, and medicine, 1987, Volume: 26, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Adult; Arachidonate Lipoxygenases; Blood Platelets; Cell Membrane; Cytosol; Humans; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Prostaglandin Antagonists; Pyrazoles; Quercetin; Substrate Specificity; Umbelliferones	1987
Inhibition of leukotriene-induced contraction of guinea pig trachea by 5-lipoxygenase inhibitors. Prostaglandins, 1987, Volume: 33, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Guinea Pigs; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrazoles; SRS-A; Trachea	1987
Effect of inhibitors of arachidonic acid metabolism on efflux of intracellular enzymes from skeletal muscle following experimental damage. The Biochemical journal, 1987, Jan-15, Volume: 241, Issue:2 Topics: 2,4-Dinitrophenol; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Creatine Kinase; Cyclooxygenase Inhibitors; Dinitrophenols; Female; In Vitro Techniques; Masoprocol; Muscles; Muscular Diseases; Phenylacetates; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains	1987
The action of erythropoietin is mediated by lipoxygenase metabolites in murine fetal liver cells. Biochemical and biophysical research communications, 1987, Aug-31, Volume: 147, Issue:1 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxyanisole; Erythropoiesis; Erythropoietin; Hydroxyeicosatetraenoic Acids; Liver; Masoprocol; Meclofenamic Acid; Mice; Phosphatidylinositols; Pyrazoles	1987
Arachidonic acid metabolites and airway epithelium-dependent relaxant factor. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Biological Products; Carbachol; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Pyrazoles; Trachea	1987
The induction of ornithine decarboxylase caused by 12-O-tetradecanoylphorbol-13-acetate in isolated epidermal cells is inhibited by lipoxygenase inhibitors but not by cyclooxygenase inhibitors. European journal of pharmacology, 1987, Nov-24, Volume: 144, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Enzyme Induction; Epidermal Cells; Lipoxygenase Inhibitors; Masoprocol; Mice; Ornithine Decarboxylase; Pyrazoles; Quercetin; Tetradecanoylphorbol Acetate	1987
The role of arachidonic acid metabolism in IL-3-induced proliferation. Immunopharmacology and immunotoxicology, 1988, Volume: 10, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Cell Division; Cell Line; Indomethacin; Interleukin-3; Lipoxygenase Inhibitors; Masoprocol; Meclofenamic Acid; Propionates; Pyrazoles	1988
Role of platelet-activating factor (PAF) in the ovoimplantation in the rat: effect of the specific PAF-acether antagonist, BN 52021. Prostaglandins, 1988, Volume: 35, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Catechols; Diterpenes; Dose-Response Relationship, Drug; Embryo Implantation; Female; Ginkgolides; Indomethacin; Kinetics; Lactones; Lipoxygenase Inhibitors; Masoprocol; Platelet Activating Factor; Pyrazoles; Rats; Rats, Inbred Strains; Sulfides	1988
Comparative effects of inhibitors of arachidonic acid metabolism on erythropoiesis. Prostaglandins, leukotrienes, and essential fatty acids, 1988, Volume: 31, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxyanisole; Cyclooxygenase Inhibitors; Erythropoiesis; Hematopoietic Stem Cells; Lipoxygenase Inhibitors; Masoprocol; Meclofenamic Acid; Mice; Pyrazoles	1988
Acute uteroplacental ischemic embryo: lactic acid accumulation and prostaglandin production in the fetal rat brain. Journal of neurochemistry, 1988, Volume: 51, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzoquinones; Brain; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Female; Indomethacin; Ischemia; Lactates; Lactic Acid; Lipoxygenase Inhibitors; Masoprocol; Placenta; Pregnancy; Prostaglandins; Prostaglandins E; Prostaglandins F; Pyrazoles; Quinones; Rats; Uterus	1988
Increased airways responsiveness to histamine induced by platelet activating factor in the guinea-pig: possible role of lipoxygenase metabolites. Agents and actions, 1988, Volume: 24, Issue:1-2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Aspirin; Atropine Derivatives; Bronchi; Female; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase; Male; Masoprocol; Platelet Activating Factor; Pyrazoles; Vagotomy	1988
Inactivation of soybean lipoxygenase by lipoxygenase inhibitors in the presence of 15-hydroperoxyeicosatetraenoic acid. Biochemical pharmacology, 1988, Dec-01, Volume: 37, Issue:23 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Benzeneacetamides; Ethanol; Ethylene Glycol; Ethylene Glycols; Glycine max; Hydroxamic Acids; Leukotrienes; Linoleic Acid; Linoleic Acids; Lipid Peroxides; Lipoxygenase Inhibitors; Masoprocol; Pyrazoles	1988
Simple procedure for measuring the pharmacodynamics and analgesic potential of lipoxygenase inhibitors. Journal of pharmacological methods, 1988, Volume: 20, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipoxygenase Inhibitors; Masoprocol; Mice; Pain; Pyrazoles	1988
Mechanism of action of platelet-activating factor on guinea-pig lung parenchyma strips. Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:9 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Guinea Pigs; Immunoenzyme Techniques; Lung; Masoprocol; Methacrylates; Muscle Contraction; Platelet Activating Factor; Pyrazoles; Sulfonamides; Thromboxane A2; Thromboxane B2	1988
Endothelium-dependent modulation of the pressor activity of arginine vasopressin in the isolated superior mesenteric arterial bed of the rat. British journal of pharmacology, 1988, Volume: 95, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Blood Pressure; Cholic Acids; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Masoprocol; Mesenteric Arteries; Methylene Blue; Muscle, Smooth, Vascular; Proadifen; Pyrazoles; Rats; Rats, Inbred Strains	1988
Suppression of cholesteryl ester accumulation in cultured human monocyte-derived macrophages by lipoxygenase inhibitors. Biochemical and biophysical research communications, 1985, Feb-28, Volume: 127, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Arachidonate Lipoxygenases; Catechols; Cholesterol Esters; Humans; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Pyrazoles	1985
Effect of exogenous phospholipase A2 on insulin secretion from perifused rat islets. Diabetes, 1985, Volume: 34, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcium; Catechols; Cyclooxygenase Inhibitors; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase Inhibitors; Male; Masoprocol; Perfusion; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors	1985
Mechanical response of rabbit myocardium and coronary arteries to leukotriene D4. Failure to demonstrate a role in the pathophysiology of hypoxia. Advances in myocardiology, 1985, Volume: 6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Catechols; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Heart Septum; Lipoxygenase Inhibitors; Male; Masoprocol; Myocardial Contraction; Oxygen Consumption; Pyrazoles; Rabbits; Rats; Rats, Inbred Strains; SRS-A	1985
Arachidonic acid metabolism in isolated pancreatic islets. IV. Negative ion-mass spectrometric quantitation of monooxygenase product synthesis by liver and islets. Biochimica et biophysica acta, 1985, Jun-14, Volume: 835, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Catechols; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase; Masoprocol; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxygenases; Pyrazoles; Rats; SRS-A	1985
Endothelium-dependent vasodilation by melittin: are lipoxygenase products involved? The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Bee Venoms; Catechols; Endothelium; Female; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Melitten; Muscle, Smooth, Vascular; Nitric Oxide; Phospholipases; Pyrazoles; Rabbits; Vasodilation; Vasodilator Agents	1985
Pharmacological modulation of responses of guinea-pig airways contracted with antigen and calcium ionophore A23187. British journal of pharmacology, 1985, Volume: 85, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Calcimycin; Catechols; Chromones; Drug Interactions; Epoprostenol; Guinea Pigs; Indomethacin; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Muscle Contraction; Ovalbumin; Pyrazoles; Pyrazolones; Trachea	1985
Eosinophil adherence to infective larvae of Trichinella spiralis: quantification and modulation. Immunology, 1985, Volume: 56, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Antibodies; Antibody Specificity; Catechols; Cell Adhesion; Dose-Response Relationship, Immunologic; Eosinophils; Guinea Pigs; Histamine; Larva; Male; Masoprocol; Mice; Oxygen Consumption; Pyrazoles; Rabbits; Temperature; Trichinellosis	1985
Possible non-involvement of lipoxygenase pathway in the cerebral blood flow decrease due to indomethacin. European journal of pharmacology, 1985, Aug-27, Volume: 114, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Catechols; Cerebrovascular Circulation; Chromones; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains; Regional Blood Flow; SRS-A; Vasoconstriction	1985
Pharmacological modulation of activation-secretion of rat serosal mast cells by chymase, an endogenous secretory granule protease. Immunology, 1985, Volume: 56, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acids; Catechols; Chymases; Deoxyadenosines; Dideoxyadenosine; Diethylcarbamazine; Dose-Response Relationship, Drug; Endopeptidases; Exocytosis; Hexosaminidases; Immunoglobulin E; In Vitro Techniques; Indomethacin; Masoprocol; Mast Cells; Prostaglandin D2; Prostaglandins D; Pyrazoles; Quinacrine; Rats; Rats, Inbred Strains; Serine Endopeptidases; Theophylline	1985
An appraisal of the technique of polymorphonuclear leukocyte chemiluminescence as a means to detect compounds with antiinflammatory activity. Journal of pharmacological methods, 1985, Volume: 14, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Catechols; In Vitro Techniques; Luminescent Measurements; Male; Masoprocol; Neutrophils; Pyrazoles; Rats; Rats, Inbred Strains; Zymosan	1985
The modulation of peritoneal macrophage chemiluminescence by acute pleural inflammation, prostanoids and cyclo/lipoxygenase inhibitors. Agents and actions, 1985, Volume: 17, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acute Disease; Animals; Catechols; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Indomethacin; Ketoprofen; Lipoxygenase Inhibitors; Luminescent Measurements; Macrophages; Male; Masoprocol; Peritoneal Cavity; Pleurisy; Prostaglandins; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains	1985
Rat neutrophil activation and effects of lipoxygenase and cyclooxygenase inhibitors. The American journal of pathology, 1984, Volume: 116, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigen-Antibody Complex; Antioxidants; Calcimycin; Catechols; Cyclooxygenase Inhibitors; Cytochalasin B; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piroxicam; Pyrazoles; Pyrazolones; Rats; Superoxides; Tetradecanoylphorbol Acetate; Thiazines; Zymosan	1984
Arachidonic acid and leukotriene B4 induce aggregation of human peripheral blood mononuclear leucocytes in vitro. British journal of haematology, 1984, Volume: 58, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Cell Aggregation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indomethacin; Leukocytes; Leukotriene B4; Masoprocol; Neutrophils; Pyrazoles	1984
Beta-endorphin and adrenocorticotropin release from rat adenohypophysis in vitro: evidence for local modulation by arachidonic acid metabolites of the cyclooxygenase and lipoxygenase pathway. Neuroendocrinology, 1984, Volume: 39, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Adrenocorticotropic Hormone; Animals; Arachidonic Acids; beta-Endorphin; Catechols; Dinoprostone; Endorphins; In Vitro Techniques; Indomethacin; Male; Masoprocol; Pituitary Gland, Anterior; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains	1984
Synthesis of slow reacting substance-like activity in rabbit conjunctiva and anterior uvea. Investigative ophthalmology & visual science, 1983, Volume: 24, Issue:8 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acids; Autacoids; Catechols; Chromones; Conjunctiva; Enzyme Activation; Guinea Pigs; Ileum; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Muscle Contraction; Pyrazoles; Rabbits; Tissue Extracts; Uvea	1983
Effects of lipoxygenase inhibitors in arachidonate-induced sudden death. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Cathepsin D; Cathepsins; Death, Sudden; Glucuronidase; Lipoxygenase Inhibitors; Liver; Lung; Lysosomes; Male; Masoprocol; Pancreas; Pyrazoles; Rabbits; Thromboxane B2	1984
Comparative effects of inhibitors of the lipoxygenase enzyme system on leucocyte chemotaxis. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Catechols; Chemotaxis, Leukocyte; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Neutrophils; Propionates; Pyrazoles; Rats; Zymosan	1984
Effect of lipoxygenase inhibitors on release of slow-reacting substances from human lung. European journal of pharmacology, 1981, Jun-10, Volume: 72, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Autacoids; Catechols; Enzyme Inhibitors; Histamine Release; Humans; In Vitro Techniques; Lipoxygenase Inhibitors; Lung; Masoprocol; Pyrazoles; SRS-A	1981
A role for the lipoxygenase pathway of arachidonic acid metabolism in glucose- and glucagon-induced insulin secretion. Life sciences, 1983, Feb-21, Volume: 32, Issue:8 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acids; Biotransformation; Catechols; Cells, Cultured; Cyclic AMP; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase Inhibitors; Masoprocol; Prostaglandins E; Pyrazoles; Rats	1983
Arachidonic acid metabolism in the murine eosinophil. III. Effect of nonsteroid anti-inflammatory drugs on lymphokine-directed eosinophil migration in vivo. Journal of immunology (Baltimore, Md. : 1950), 1983, Volume: 130, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Catechols; Cell Migration Inhibition; Dose-Response Relationship, Drug; Eosinophils; Indomethacin; Lymphokines; Male; Masoprocol; Mice; Mice, Inbred CBA; Pyrazoles; Rats	1983
Stimulation and inhibition of prostacyclin formation in the gastric mucosa and ileum in vitro by anti-inflammatory agents. British journal of pharmacology, 1983, Volume: 78, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetaminophen; Animals; Anti-Inflammatory Agents; Catechols; Epoprostenol; Gastric Mucosa; Ileum; In Vitro Techniques; Male; Masoprocol; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains	1983
A rapid method for detecting inhibitors of both cyclo-oxygenase lipoxygenase metabolites of arachidonic acid. Journal of pharmacological methods, 1983, Volume: 9, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Biotransformation; Calcimycin; Catechols; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Neutrophils; Oxygenases; Propionates; Pyrazoles	1983
Human natural killer cell activity is reversibly inhibited by antagonists of lipoxygenation. Journal of immunology (Baltimore, Md. : 1950), 1983, Volume: 131, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adult; Anti-Inflammatory Agents; Antioxidants; Catechols; Cytotoxicity, Immunologic; Humans; Immunosuppressive Agents; Killer Cells, Natural; Lipoxygenase Inhibitors; Masoprocol; Monocytes; Prostaglandin-Endoperoxide Synthases; Pyrazoles	1983
Effects of antioxidants on cyclooxygenase and lipoxygenase activities in intact human platelets: comparison with indomethacin and ETYA. Prostaglandins, 1983, Volume: 26, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Antioxidants; Blood Platelets; Catechols; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipoxygenase; Masoprocol; Naphthols; Propyl Gallate; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Quercetin	1983
Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets. Prostaglandins, leukotrienes, and medicine, 1984, Volume: 13, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alkynes; Arachidonic Acids; Blood Platelets; Catechols; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukocytes; Lipoxygenase Inhibitors; Masoprocol; Pyrazoles	1984
Arachidonic acid metabolism and thyrotropin secretion in vitro. European journal of pharmacology, 1984, Feb-10, Volume: 98, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Female; In Vitro Techniques; Indomethacin; Masoprocol; Phospholipases A; Phospholipases A2; Pituitary Gland; Pyrazoles; Quinacrine; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin; Thyrotropin-Releasing Hormone	1984
Inhibition of steroid production in Leydig cells by non-steroidal anti-inflammatory and related compounds: evidence for the involvement of lipoxygenase products in steroidogenesis. The Biochemical journal, 1984, Apr-15, Volume: 219, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Aspirin; Catechols; In Vitro Techniques; Indomethacin; Leydig Cells; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Pregnenolone; Propionates; Pyrazoles; Rats; Testosterone	1984
Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations. Inflammation, 1984, Volume: 8, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Neutrophils; Pyrazoles; Quercetin; Rats	1984
Human and murine natural killer cell activity may require lipoxygenation of arachidonic acid. The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:3 Pt 2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Antibody-Dependent Cell Cytotoxicity; Antioxidants; Arachidonic Acid; Arachidonic Acids; Catechols; Cell Line; Humans; Indomethacin; Killer Cells, Natural; Leukemia, Myeloid, Acute; Masoprocol; Pyrazoles	1984
Possible involvement of lipoxygenase products of arachidonic acid pathway in ovulation. Prostaglandins, 1983, Volume: 26, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Chromones; Fatty Acids, Unsaturated; Female; Lipoxygenase Inhibitors; Masoprocol; Ovulation; Pyrazoles; Rats; Rats, Inbred Strains	1983
Lipoxygenation of arachidonic acid: a pivotal step in stimulus-secretion coupling in the pancreatic beta cell. Endocrinology, 1982, Volume: 111, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Catechols; Islets of Langerhans; Lipoxygenase Inhibitors; Masoprocol; Pyrazoles; Tolbutamide	1982
PAF-induced death in NMRI mice--a suitable shock model for testing new PAF receptor antagonists. Correlation with eicosanoid related substances. Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Disease Models, Animal; Diterpenes; Eicosanoids; Female; Ginkgolides; Lactones; Masoprocol; Mice; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock; Species Specificity; Triazoles	1993
Effects of eicosanoid metabolism inhibitors on growth of a human gastric tumour cell line (HGT). Cancer letters, 1993, Sep-15, Volume: 73, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Aspirin; Cell Division; Eicosanoids; Fatty Acids; Humans; Masoprocol; Membrane Lipids; Phospholipids; Stomach Neoplasms; Tumor Cells, Cultured	1993
Evidence that endogenous generation of leukotrienes does not regulate proliferation of malignant hemopoietic cell lines. Leukemia research, 1993, Volume: 17, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Benzeneacetamides; Blast Crisis; Burkitt Lymphoma; Cell Division; Epoprostenol; Hematopoietic System; Humans; Hydroxamic Acids; Indoles; Leukemia; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Masoprocol; Tumor Cells, Cultured	1993
Role of endothelium-derived metabolites of arachidonic acid in enhanced pulmonary artery contractions in female rabbits. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Methacholine Chloride; Potassium Chloride; Pulmonary Artery; Rabbits; Sex Characteristics; Thromboxane B2; Vasoconstriction	1996
Effects of arachidonic acid metabolism on hypoxic vasoconstriction in rabbit lungs. European journal of pharmacology, 1998, Sep-04, Volume: 356, Issue:2-3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Drug Interactions; Female; Hypoxia; Indoles; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Rabbits; Vasoconstriction	1998