bw-755c has been researched along with leukotriene b4 in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (80.95) | 18.7374 |
| 1990's | 8 (19.05) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lenti, L; Pasetto, N; Piccione, E; Pontieri, G; Ticconi, C; Zicari, A | 1 |
| Amalsadvala, TM; Vaughn, DM | 1 |
| Morita, I; Murota, S; Okiji, T; Sunada, I | 1 |
| Hoffmann, G; Mallinger, J; Mehlber, L; Neu, I; Prosiegel, M; Ruhenstroth-Bauer, G; Vogl, S; Wildfeuer, A | 1 |
| Fitzgerald, MF; Parente, L; Whittle, BJ | 1 |
| Bednar, MM; Hatala, MA; Kraemer, R; Mullane, KM | 1 |
| Autore, G; Capasso, F; Di Carlo, G; Mascolo, N | 1 |
| Lefkowith, JB | 1 |
| Anderson, CB; Deschryver, K; Mangino, MJ; Turk, J | 1 |
| Fukuda, T; Kobayashi, K; Nakamura, H; Sakuma, H; Sato, H | 1 |
| Boctor, AM; Burke, C; Hovinga, ME | 1 |
| Brooks, PM; Forrest, MJ; Zammit, V | 1 |
| Adkinson, NF; Gottlieb, JE; McGeady, M; Sylvester, JT | 1 |
| Dunn, MJ; Emancipator, SN; Nakazawa, M; Rahman, MA | 1 |
| Follenfant, RL; Garland, LG; Higgs, GA | 1 |
| Anderson, GP; Fennessy, MR | 1 |
| Lefkowith, JB; Morrison, AR; Schreiner, GF | 1 |
| Moncada, S; Salmon, JA; Tilling, LC | 1 |
| Cromwell, O; Kay, AB; Mallet, AI; Shaw, RJ; Walsh, GM | 1 |
| Issekutz, AC; Ripley, M; Rochon, Y | 1 |
| Catt, KJ; Kiesel, L; Naor, Z; Vanderhoek, JY | 1 |
| Beetens, JR; Coene, MC; De Clerck, F; Loots, W; Somers, Y | 1 |
| Aked, D; Foster, SJ; Howarth, A; McCormick, ME | 1 |
| Carey, F; Forder, RA | 1 |
| Gordon, AH; Limãos, EA; Ribeiro, EB | 1 |
| Dreyling, KW; Hoppe, U; Kozuschek, W; Morgenroth, K; Peskar, BA; Peskar, BM | 1 |
| Bankhurst, AD; Imir, T; Sibbitt, WL | 1 |
| Boctor, AM; Eickholt, M; Pugsley, TA | 1 |
| Mita, H; Shida, T; Yui, Y | 1 |
| Roth, JA; Webb, DS | 1 |
| Barnes, NC; Costello, JF; Piper, PJ; Zakrzewski, JT | 1 |
| Moodley, I; Stuttle, A | 1 |
| Colotta, F; de Gaetano, G; Semeraro, N; Villa, S | 1 |
| Denzlinger, C; Hagmann, W; Keppler, D | 1 |
| Moncada, S; Salmon, JA; Simmons, PM | 1 |
| Palmer, RM; Salmon, JA; Simmons, PM | 1 |
| Higgs, GA; Moncada, S; Mugridge, KG; Vane, JR | 1 |
| Ho, TF; Lin, CN; Teng, CM; Wang, JP | 1 |
| Amsterdam, EA; Fletcher, MP; Longhurst, JC; Pan, HL; Rendig, SV; Symons, JD | 1 |
| Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M | 1 |
| Colombo, C; DiPasquale, G; Fryer, LR; Greenspan, PD; Haston, W; Healy, C; Kotyuk, B; Pastor, G; Pellas, TC; Raychaudhuri, A | 1 |
| Baethmann, A; Goerke, U; Kempski, O; Peters, J; Staub, F; Winkler, A | 1 |
42 other study(ies) available for bw-755c and leukotriene b4
| Article | Year |
|---|---|
Influence of labor and oxytocin on in vitro leukotriene release by human fetal membranes and uterine decidua at term gestation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adult; Calcimycin; Culture Techniques; Cycloheximide; Decidua; Extraembryonic Membranes; Female; Humans; Labor, Obstetric; Leukotriene B4; Oxytocin; Pregnancy; SRS-A | 1992 |
Characterization of leukotriene B4 synthesis in canine polymorphonuclear leukocytes.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzeneacetamides; Calcimycin; Dogs; Dose-Response Relationship, Drug; Female; Hydroxamic Acids; In Vitro Techniques; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; Male; Neutrophils; Temperature | 1992 |
The role of leukotriene B4 in neutrophil infiltration in experimentally-induced inflammation of rat tooth pulp.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cell Movement; Cyclophosphamide; Dental Pulp; Indomethacin; Leukocyte Count; Leukotriene B4; Lipopolysaccharides; Male; Neutrophils; Pulpitis; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Suppression of experimental autoimmune encephalomyelitis by dual cyclo-oxygenase and 5-lipoxygenase inhibition.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Cyclooxygenase Inhibitors; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Leukotriene B4; Lipoxygenase Inhibitors; Pyrazoles; SRS-A | 1989 |
Release of PAF-acether and eicosanoids from guinea-pig alveolar macrophages by FMLP: effect of cyclo-oxygenase and lipoxygenase inhibition.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Benzeneacetamides; Cyclooxygenase Inhibitors; Guinea Pigs; Hydroxamic Acids; In Vitro Techniques; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pulmonary Alveoli; Pyrazoles; Radioimmunoassay; Thromboxane B2 | 1989 |
A neutrophil-derived cytochrome P450-dependent metabolite of arachidonic acid modulates neutrophil behavior.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Adhesion; Cell Aggregation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dogs; Leukotriene B4; Mixed Function Oxygenases; Neutrophils; Pyrazoles; Superoxides | 1987 |
Effect of cholera toxin on the production of eicosanoids by rat jejunum.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholera Toxin; Dinoprostone; Eicosanoic Acids; In Vitro Techniques; Jejunum; Leukotriene B4; Male; Muscle, Smooth; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains; SRS-A | 1987 |
Essential fatty acid deficiency inhibits the in vivo generation of leukotriene B4 and suppresses levels of resident and elicited leukocytes in acute inflammation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Fatty Acids, Essential; Inflammation; Leukotriene B4; Macrophages; Male; Mice; Pyrazoles | 1988 |
Arachidonate lipoxygenase products and renal allograft rejection in dogs.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Dogs; Graft Rejection; Hydroxyeicosatetraenoic Acids; Kidney Cortex; Kidney Transplantation; Leukotriene B4; Lipoxygenase Inhibitors; Pyrazoles; Transplantation, Homologous | 1987 |
[Role of mucosal leukotriene in mucosal damage caused by 0.6N HCL in rat stomach].
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Gastric Mucosa; Hydrochloric Acid; Leukotriene B4; Male; Pyrazoles; Rats; Rats, Inbred Strains; Stomach Diseases | 1987 |
Arachidonic acid-induced pleurisy (ARIP): an in vivo model for testing 5-lipoxygenase inhibition.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Arachidonic Acids; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Pleurisy; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Inhibition of leucotriene B4 synthesis by BW 755c does not reduce polymorphonuclear leucocyte (PMNL) accumulation induced by monosodium urate crystals.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Indomethacin; Inflammation; Leukocyte Count; Leukotriene B4; Male; Neutrophils; Prostaglandins E; Prostaglandins E, Synthetic; Pyrazoles; Rats; Rats, Inbred Strains; Uric Acid | 1988 |
Effects of cyclo- and lipoxygenase inhibitors on hypoxic vasoconstriction in isolated ferret lungs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Gas Analysis; Blood Pressure; Catechols; Cyclooxygenase Inhibitors; Dinoprost; Ferrets; Hydrogen-Ion Concentration; Hypoxia; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Organ Culture Techniques; Oxygen; Potassium Chloride; Prostaglandins F; Pyrazoles; Vasoconstriction | 1988 |
Increased leukotriene B4 synthesis in immune injured rat glomeruli.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Female; Fluorescent Antibody Technique; Gas Chromatography-Mass Spectrometry; Glomerulonephritis; Kidney Glomerulus; Leukotriene B4; Male; Microscopy, Electron; Nephritis; Neutrophils; Pyrazoles; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: effects on acute inflammatory responses.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acute Disease; Animals; Arachidonate Lipoxygenases; Dinoprostone; Female; Hydroxamic Acids; Inflammation; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred Strains; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
Lipoxygenase metabolites mediate increased airways responsiveness to histamine after acute platelet activating factor exposure in the guinea-pig.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Aspirin; Bronchi; Chromones; Female; Guinea Pigs; Histamine; Leukotriene B4; Lipoxygenase; Lung Compliance; Male; Platelet Activating Factor; Pyrazoles; Quinolinium Compounds; SRS-A | 1988 |
Murine glomerular leukotriene B4 synthesis. Manipulation by (n-6) fatty acid deprivation and cellular origin.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Calcimycin; Chromatography, High Pressure Liquid; Dinoprostone; Dose-Response Relationship, Drug; Fatty Acids; Indomethacin; Kidney Glomerulus; Leukotriene B4; Mice; Pyrazoles; Radioimmunoassay; Rats; Rats, Inbred Lew | 1988 |
Evaluation of inhibitors of eicosanoid synthesis in leukocytes: possible pitfall of using the calcium ionophore A23187 to stimulate 5' lipoxygenase.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonate Lipoxygenases; Calcimycin; Humans; Leukotriene B4; Lipoxygenase; Neutrophils; Propionates; Pyrazoles; Thromboxane B2; Zymosan | 1985 |
Inhibition of leukotriene C4 and B4 generation by human eosinophils and neutrophils with the lipoxygenase pathway inhibitors U60257 and BW755C.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Cross Reactions; Eosinophils; Epoprostenol; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Pyrazoles; Radioimmunoassay; SRS-A | 1985 |
Synergistic inhibition of complement induced granulocyte margination by BW755C and calcium channel blockers.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Agranulocytosis; Animals; Calcium; Calcium Channel Blockers; Cell Aggregation; Chemotactic Factors; Complement System Proteins; Female; Granulocytes; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pyrazoles; Rabbits; Verapamil | 1985 |
Mechanism of action of gonadotropin releasing hormone: role of lipoxygenase products of arachidonic acid in luteinizing hormone release.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catechols; Cells, Cultured; Gonadotropin-Releasing Hormone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Luteinizing Hormone; Masoprocol; Pituitary Gland; Pyrazoles; Rats; SRS-A | 1985 |
Ketoconazole inhibits the biosynthesis of leukotrienes in vitro and in vivo.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bronchi; Catechols; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Ketoconazole; Leukotriene B4; Lipoxygenase Inhibitors; Male; Masoprocol; Neutrophils; Pyrazoles; Rabbits; Rats; Rats, Inbred Strains; Reticulocytes; SRS-A | 1986 |
Leukocyte recruitment in the subcutaneous sponge implant model of acute inflammation in the rat is not mediated by leukotriene B1.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acute Disease; Animals; Blood Proteins; Calcimycin; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Inflammation; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Prostaglandins E; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Strains; Skin | 1986 |
Radioimmunoassay of LTB4 and 6-trans LTB4: analytical and pharmacological characterisation of immunoreactive LTB4 in ionophore stimulated human blood.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antibodies; Antibody Specificity; Calcimycin; Catechols; Chromatography, High Pressure Liquid; Cross Reactions; Dose-Response Relationship, Drug; Female; Humans; Leukotriene B4; Male; Masoprocol; Pyrazoles; Pyrazolones; Rabbits; Radioimmunoassay; Thromboxane B2; Time Factors | 1986 |
Effect of endogenous pyrogen, corticosteroids and inhibitors of prostaglandins and leukotrienes on the plasma concentrations of haptoglobin and fibrinogen in rats.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenal Cortex Hormones; Adrenalectomy; Animals; Anti-Inflammatory Agents; Fibrinogen; Haptoglobins; Ibuprofen; Leukotriene B4; Male; Prostaglandin Antagonists; Pyrazoles; Pyrogens; Rats; Rats, Inbred Strains | 1985 |
Leukotriene synthesis by human gastrointestinal tissues.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenocarcinoma; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Colonic Neoplasms; Digestive System; Dinoprostone; Gastric Mucosa; Humans; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Masoprocol; Muscle, Smooth; Prostaglandins E; Pyrazoles; SRS-A | 1986 |
Reversible inhibition of lymphokine-activated killer cell activity by lipoxygenase-pathway inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Centrifugation, Density Gradient; Chromium; Cytotoxicity, Immunologic; Humans; Interleukin-2; Killer Cells, Natural; Leukotriene B4; Lipoxygenase Inhibitors; Lymphokines; Masoprocol; Pyrazoles | 1986 |
Meclofenamate sodium is an inhibitor of both the 5-lipoxygenase and cyclooxygenase pathways of the arachidonic acid cascade in vitro.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Arachidonic Acids; Cattle; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Meclofenamic Acid; ortho-Aminobenzoates; Prostaglandins E; Pyrazoles; Seminal Vesicles | 1986 |
Effect of AA-861, a 5-lipoxygenase inhibitor, on leukotriene synthesis in human polymorphonuclear leukocytes and on cyclooxygenase and 12-lipoxygenase activities in human platelets.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Blood Platelets; Calcimycin; Diethylcarbamazine; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Quinones; SRS-A | 1986 |
Relationship of glucocorticoid suppression of arachidonic acid metabolism to alteration of neutrophil function.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Dexamethasone; Diglycerides; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotriene B4; Masoprocol; Neutrophils; Phospholipids; Pyrazoles; Triglycerides; Zymosan | 1987 |
Detection of sputum eicosanoids in cystic fibrosis and in normal saliva by bioassay and radioimmunoassay.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adolescent; Adult; Arachidonic Acids; Biological Assay; Child; Cystic Fibrosis; Female; Humans; Leukotriene B4; Male; Prostaglandins; Pyrazoles; Radioimmunoassay; Saliva; Sputum; SRS-A | 1987 |
Evidence for a dual pathway in platelet activating factor-induced aggregation of rat polymorphonuclear leucocytes.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cell Aggregation; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; Neutrophils; Platelet Activating Factor; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Strains | 1987 |
Arachidonic acid and leukotriene B4 induce aggregation of human peripheral blood mononuclear leucocytes in vitro.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Cell Aggregation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indomethacin; Leukocytes; Leukotriene B4; Masoprocol; Neutrophils; Pyrazoles | 1984 |
Role of peptide leukotrienes and their hepatobiliary elimination in endotoxin action.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Bile; Chromones; Dexamethasone; Diethylcarbamazine; Endotoxins; Female; Ibuprofen; Indomethacin; Leukotriene B4; Liver; Metabolic Clearance Rate; Mice; Pyrazoles; Rats; Rats, Inbred Strains; Shock, Septic; SRS-A | 1984 |
The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Dexamethasone; Dinoprostone; Exudates and Transudates; Fatty Acids, Unsaturated; Indomethacin; Inflammation; Leukocyte Count; Leukocytes; Leukotriene B4; Male; Prostaglandins E; Pyrazoles; Rats; Thromboxane B2 | 1983 |
Release of leukotriene B4 from human neutrophils measured by specific radioimmunoassay.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Calcimycin; Cytochalasin B; Dinoprostone; Humans; Indomethacin; Kinetics; Leukotriene B4; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Prostaglandins E; Pyrazoles; Radioimmunoassay; Thromboxane B2 | 1983 |
Inhibition of tissue damage by the arachidonate lipoxygenase inhibitor BW755C.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Dexamethasone; Foreign-Body Reaction; Indomethacin; Inflammation; Leukocytes; Leukotriene B4; Male; Pyrazoles; Rats; SRS-A | 1984 |
Effect of norathyriol, isolated from Tripterospermum lanceolatum, on A23187-induced pleurisy and analgesia in mice.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Analgesia; Animals; Calcimycin; Dinoprostone; Female; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Mice; Neutrophils; Pleurisy; Radioimmunoassay; Xanthenes | 1994 |
Limitation of myocardial infarct size in pigs with a dual lipoxygenase-cyclooxygenase blocking agent by inhibition of neutrophil activity without reduction of neutrophil migration.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Analysis of Variance; Animals; Cell Movement; Coronary Circulation; Female; Hemodynamics; Leukotriene B4; Male; Myocardial Infarction; Neutrophils; Peroxidase; Superoxides; Swine | 1993 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
LTB4-induced transient neutropenia in the rat: a model for evaluating efficacy and bioavailability of LTB4 receptor antagonists.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Dexamethasone; Hydroxyurea; Indomethacin; Leukocyte Count; Leukotriene B4; Male; Models, Biological; Naproxen; Neutropenia; Neutrophils; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene B4 | 1993 |
Clearance and metabolism of arachidonic acid by C6 glioma cells and astrocytes.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Astrocytes; Culture Media; Cyclooxygenase Inhibitors; Dinoprost; Glioma; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; Tumor Cells, Cultured | 1995 |