Page last updated: 2024-08-23

bw-755c and arachidonic acid

bw-755c has been researched along with arachidonic acid in 128 studies

Research

Studies (128)

Timeframe	Studies, this research(%)	All Research%
pre-1990	91 (71.09)	18.7374
1990's	33 (25.78)	18.2507
2000's	4 (3.13)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Apgar, JR; Mescher, MF; O'Rourke, AM	1
Guivarc'h, P; Iliou, JP; Jourd'heuil, D; Robin, F; Serkiz, B; Vilaine, JP; Volland, JP	1
Chapkin, RS; Lee, DY; Lupton, JR	1
Cowden, WB; Hugh, AR; Simmons, RD; Willenborg, DO	1
Gross, R; Ramanadham, S; Turk, J	1
Furman, BL; Gray, GA; Parratt, JR	1
Braquet, P; Lagente, V; Mencia-Huerta, JM; Pons, F; Touvay, C	1
Ishizaki, Y; Murota, S	1
Ebbesen, MA; Gibel, L; Goodwin, JS; Harford, AM; Shopp, GM; Smith, AY; Sterling, WA	1
Lonigro, AJ; Sprague, RS; Stephenson, AH	1
Beraud, M; Cambon, C; Didier, A; Forgue, MF; Pinelli, E; Pipy, B; Souqual, MC; Vandaele, J	1
McGiff, JC; Oyekan, AO; Quilley, J	1
Hirota, K; Ikegami, H; Kadowaki, K; Koike, K; Miyake, A; Ohmichi, M; Tanizawa, O; Yamaguchi, M	1
Calixto, JB; Cruz, AB; Medeiros, YS; Yunes, RA; Zanini Júnior, JC	1
Holub, BJ; Thomas, LM	1
Quilley, J; Sarubbi, D	1
Aréjola, JM; Guarner, F; Prieto, J; Quiroga, J; Rodríguez Ortigosa, C; Rodríguez-Sanromán, JL	1
Alonso, MT; Garcia-Sancho, J; Sanchez, A	1
Bhattacherjee, P; Guo, A; Kulkarni, P; Ohia, E; Xu, JT	1
Ikeda, Y; Long, DM	1
Judd, AM; Koike, K; MacLeod, RM	2
Boctor, AM; Pugsley, TA	1
Miura, K; Nozawa, Y; Okano, Y; Yamada, K	1
Baethmann, A; Hammersen, F; Unterberg, A; Wahl, M	1
Disa, J; Kowalska, MA; Rao, AK	1
Bereziat, G; Breton, M; Chevy, F; Colard, O; Pepin, D; Polonovski, J	1
Nakashima, S; Nozawa, Y; Tohmatsu, T	1
Carroll, MA; Rosenthal, WS; Schwartzman, ML; Stahl, RE; Stein, BE	1
Bjertnaes, L; Kjaeve, J; Vaage, J	1
Azizova, OA; Borin, ML; Ivanova, MA; Khodorov, BI; Markov, CM; Pinelis, VG	1
Iakhnitsa, IA; Piliavskiĭ, AI; Skryma, RN	1
Abraham, NG; Lutton, JD; Schwartzman, ML	1
Burkart, V; Epstein, S; Kawai, K; Kiesel, U; Kolb, H; Maruta, K; Schmidt, M	1
Farnam, J; Giclas, PC; Grant, JA; Hunt, C; Lett-Brown, MA; Thueson, DO	1
Bednar, MM; Hatala, MA; Kraemer, R; Mullane, KM	1
Gordon, T; Sheppard, D; Thompson, JE	1
Iizuka, T; Ishimura, Y; Kanegasaki, S; Makino, R; Tanaka, T	1
Hartung, HP; Heininger, K; Schäfer, B; Stoll, G; Toyka, KV	1
Canonico, PL; Cronin, MJ; MacLeod, RM; Scapagnini, U; Sortino, MA; Speciale, C	1
Canonico, PL; Judd, AM; Koike, K; MacLeod, RM; Valdenegro, CA	1
Bednar, M; Mullane, KM; Pinto, A; Smith, B	1
Jondal, M; Kullman, C; Lindgren, JA; Rossi, P	1
Demharter, R; Gärtner, R; Greil, W; Horn, K	1
Catt, KJ; Kiesel, L; Naor, Z; Vanderhoek, JY	1
Ishitoya, J; Nagai, Y; Takenawa, T	1
Conn, PJ; Sanders-Bush, E	1
Beetens, JR; Coene, MC; De Clerck, F; Loots, W; Somers, Y	1
Dreyling, KW; Hoppe, U; Kozuschek, W; Morgenroth, K; Peskar, BA; Peskar, BM	1
Maridonneau-Parini, I; Tauber, AI; Tringale, SM	1
Mita, H; Shida, T; Yui, Y	1
Roth, JA; Webb, DS	1
Abraham, NG; Mullane, KM; Pinto, A	1
Bennett, A; Capasso, F; Tavares, IA; Tsang, R	1
Desforges, JF; Snyder, DS	1
Boukili, MA; Bureau, M; Lagente, V; Lefort, J; Lellouch-Tubiana, A; Malanchère, E; Vargaftig, BB	1
Wallace, JL; Whittle, BJ	1
Dunkel, CG; Evers, AS; Needleman, P; Saffitz, JE	1
Murlas, CG; Thorpe, JE	1
Kim, SD; Marshall, BE; Marshall, C	1
Chan, KM; Turk, J	1
Mahadevappa, VG	1
Edwards, RH; Jackson, MJ; Wagenmakers, AJ	1
Nakashima, S; Nozawa, Y; Shirato, L; Takenaka, A; Tohmatsu, T	1
Cook, JA; Halushka, PV; Katz, SA; Wise, WC	1
Bennett, A; Capasso, F; Rennie, JA; Tavares, IA; Tsang, R	1
Beckman, BS; Fisher, JW; King, L; Mason-Garcia, M; Nystuen, L	1
Bertrand, C; Frossard, N; Landry, Y; Tschirhart, E	1
Fleisher, LN	1
Beckman, B; Nystuen, L	1
Easom, RA; Hughes, JH; Lacy, PE; McDaniel, ML; Scharp, DW; Turk, J; Wolf, BA	1
Bekemeier, H; Giessler, AJ; Zarnack, S	1
Cooper, DR; Kelliher, GJ; Kowey, PR	1
Reynolds, CH	1
Carey, F; Edmonds, AE; Forder, RA; Haworth, D	1
Brooks, RR; Doerr, IL; Kaufman, J	1
Carbonell, L; Parellada, PP	1
Colca, JR; McDaniel, ML; Turk, J	1
Zawalich, K; Zawalich, W	1
Colca, J; Comens, PG; Jakschik, B; McDaniel, ML; Turk, J; Wolf, BA	1
Dangelmaier, C; Mauco, G; Smith, JB	1
Förstermann, U; Neufang, B	1
Kojima, I; Kojima, K; Rasmussen, H	1
Boeynaems, JM; Galand, N; Ketelbant, P	1
Canonico, PL; Scapagnini, U; Sortino, MA; Speciale, C	1
Falkay, G; Pacsa, AS; Szekeres-Bartho, J; Török, A	1
Boughton-Smith, NK; Whittle, BJ	1
Lee, HK; Murlas, C	1
Carter, AJ; Heptinstall, S	1
Carlson, RP; Chang, J; Lewis, AJ; O'Neill-Davis, L	1
Colotta, F; de Gaetano, G; Semeraro, N; Villa, S	1
Feduska, R; Lefer, AM; Roth, DM; Smith, JB	1
Andersson, RG; Norrby, K	1
Corzo, J; Fremont-Smith, M; Guarner, F; Prieto, J; Quiroga, J; Rodriguez, JL	1
Higgs, GA; Moncada, S; Mugridge, KG; Vane, JR	1
Bhattacherjee, P; Eakins, KE; Williams, RN	1
Appleby, BJ; Buck, DC; Casey, FB	1
Harvey, J; Osborne, DJ	1
Boughton-Smith, NK; Hawkey, CJ; Whittle, BJ	1
Moncada, S; Mullane, KM; Read, N; Salmon, JA	1
Canonico, PL; Judd, AM; MacLeod, RM; Valdenegro, CA	1
Chang, J; Cherney, ML; Lewis, AJ; Skowronek, MD	1
Seaman, WE; Woodcock, J	1
Adams, T; Manley, G; Steiner, S	1
Mallarkey, G; Smith, GM	1
Caen, JP; Hardisty, R; Levy-Toledano, S; Maclouf, J; Savariau, E	1
Kohen, F; Naor, Z; Reich, R; Tsafriri, A	1
Bodach, E; Borgeat, P; Coceani, F; Jhamandas, VM; Labuc, J; Olley, PM	1
Mitchell, HW	1
Duniec, Z; Robak, J	1
Fujimoto, WY; Metz, SA; Robertson, RP	1
Johns, E; Michael, J; Richards, NT; Wu, XC	2
Adachi, T; Nakamura, T; Nakashima, S; Nozawa, Y; Saji, S	1
Boughton-Smith, NK; Deakin, AM; Follenfant, RL; Garland, LG; Whittle, BJ	1
Delton, I; Gharib, A; Lagarde, M; Pace-Asciak, CR; Reynaud, D; Sarda, N	1
Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M	1
Denizot, Y; Najid, A; Rigaud, M	1
Arnould, T; Dieu, M; Knott, I; Michiels, C; Remacle, J	1
Campbell, WB; Pfister, SL	1
Baethmann, A; Goerke, U; Kempski, O; Peters, J; Staub, F; Winkler, A	1
Conzen, J; Grimminger, F; Kiss, L; Seeger, W; Weissmann, N	1
Geertsma, MF; Nibbering, PH; Van Den Barselaar, MT; Van Furth, R; Zheng, L; Zomerdijk, TP	1
Lutnicki, K; Szpringer, E; Wróbel, J	1
Baethmann, A; Kempski, O; Peters, J; Staub, F; Winkler, AS	1
Chang, LC; Wang, JP	1
Bhattacharjee, S; Dhara, AK; Nag Chaudhuri, AK; Pal, S; Sen, T	1
Adhikari, D; Karmakar, S; Kumar, KT; Pal, S; Roy, DK; Samanta, SK; Sen, T	1

Other Studies

128 other study(ies) available for bw-755c and arachidonic acid

Article	Year
IgE receptor-mediated arachidonic acid release by rat basophilic leukemia (RBL-2H3) cells: possible role in activating degranulation. Molecular immunology, 1992, Volume: 29, Issue:11 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Arachidonic Acid; Cell Degranulation; Dose-Response Relationship, Immunologic; Fatty Acids; Inositol Phosphates; Ionomycin; Leukemia, Basophilic, Acute; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Quercetin; Quinacrine; Rats; Receptors, IgE; Serotonin; Signal Transduction; Time Factors	1992
Kinetics of photoperoxidation of arachidonic acid: molecular mechanisms and effects of antioxidants. Lipids, 1992, Volume: 27, Issue:12 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Antioxidants; Arachidonic Acid; beta Carotene; Carotenoids; Free Radicals; Indomethacin; Kinetics; Oxidation-Reduction; Peroxides; Photochemistry; Photosensitizing Agents; Probucol; Vitamin E	1992
Prostaglandin profile and synthetic capacity of the colon: comparison of tissue sources and subcellular fractions. Prostaglandins, 1992, Volume: 43, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Caffeic Acids; Colon; Cytosol; Dinoprostone; Epoprostenol; Indomethacin; Intestinal Mucosa; Male; Microsomes; Muscle, Smooth; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred Strains	1992
Suppression of active but not passive autoimmune encephalomyelitis by dual cyclo-oxygenase and 5-lipoxygenase inhibition. Acta neurologica Scandinavica, 1992, Volume: 85, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cyclooxygenase Inhibitors; Encephalomyelitis, Autoimmune, Experimental; Female; Lipoxygenase Inhibitors; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Spinal Cord; Tumor Necrosis Factor-alpha	1992
Arachidonic acid induces an increase in the cytosolic calcium concentration in single pancreatic islet beta cells. Biochemical and biophysical research communications, 1992, Apr-30, Volume: 184, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Calcium; Cytosol; Egtazic Acid; Flow Cytometry; Fluorescent Dyes; Fura-2; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Nifedipine; Potassium Chloride	1992
Endotoxin-induced impairment of vascular reactivity in the pithed rat: role of arachidonic acid metabolites. Circulatory shock, 1990, Volume: 31, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Endotoxins; Epoprostenol; Flurbiprofen; Hemodynamics; Iloprost; Male; Norepinephrine; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Spinal Cord; Sympathetic Nervous System	1990
Comparison of the effects of intra-arterial and aerosol administration of endothelin-1 (ET-1) in the guinea-pig isolated lung. British journal of pharmacology, 1991, Volume: 102, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Aerosols; Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Endothelins; Guinea Pigs; Histamine Release; In Vitro Techniques; Indomethacin; Injections, Intra-Arterial; Lung; Male; Masoprocol; Perfusion; Respiratory Function Tests; SRS-A; Thromboxane A2	1991
Arachidonic acid metabolism in cultured astrocytes: presence of 12-lipoxygenase activity in the intact cells. Neuroscience letters, 1991, Oct-14, Volume: 131, Issue:2 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Astrocytes; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Hydroxyeicosatetraenoic Acids; Indomethacin; Pregnancy; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet	1991
Murine thymocyte lysis by inhibitors of arachidonic acid metabolism. Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21B Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenal Cortex Hormones; Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Caffeic Acids; Cells, Cultured; Dexamethasone; Dinoprostone; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred C57BL; Spleen; Thymus Gland	1991
Role of arachidonic acid metabolites in the pathogenesis of acute lung injury. Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Diethylcarbamazine; Disease Models, Animal; Dogs; Ethchlorvynol; Indomethacin; Leukotrienes; Lung; Male; Methacrylates; Neutrophils; Pulmonary Edema; Respiratory Distress Syndrome; Tetradecanoylphorbol Acetate; Thromboxanes	1991
Possible implication of arachidonic acid metabolism in the decrease of chemiluminescence production after exposure of murine peritoneal macrophages to diethylnitrosamine and tumour promoter, 12-O-tetradecanoylphorbol-13-acetate. Carcinogenesis, 1991, Volume: 12, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cell Survival; Culture Media; Cyclooxygenase Inhibitors; Diethylnitrosamine; Dose-Response Relationship, Drug; Extracellular Space; Female; Indomethacin; Intracellular Fluid; Isoquinolines; Kinetics; Leukotrienes; Luminescent Measurements; Macrophage Activation; Macrophages; Mice; Oxygen; Peritoneal Cavity; Phospholipids; Piperazines; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tritium	1991
Cytochrome P-450-dependent vasodilator responses to arachidonic acid in the isolated, perfused kidney of the rat. Circulation research, 1991, Volume: 68, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Clotrimazole; Cytochrome P-450 Enzyme System; In Vitro Techniques; Indomethacin; Kidney; Male; Oxazines; Phenylephrine; Rats; Rats, Inbred Strains; Renal Circulation; Sulfonamides; Vasoconstriction; Vasodilation; Vasodilator Agents	1991
Tumor necrosis factor-alpha increases release of arachidonate and prolactin from rat anterior pituitary cells. Endocrinology, 1991, Volume: 128, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Culture Media; Female; Indomethacin; Melitten; Phospholipases A; Phospholipases A2; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha	1991
Extract and compounds obtained from Mandevilla velutina inhibit arachidonic acid-induced ear oedema in mice, but not rat stomach contraction. Prostaglandins, 1991, Volume: 41, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Edema; Female; In Vitro Techniques; Indomethacin; Isometric Contraction; Lipoxygenase Inhibitors; Male; Masoprocol; Mice; Muscle, Smooth; Plant Extracts; Pyrazoles; Rats; Stomach	1991
Inhibition of phosphatidic acid production and lysophospholipid formation in collagen-stimulated human platelets by staurosporine, a protein kinase inhibitor. Cellular signalling, 1991, Volume: 3, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alkaloids; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Humans; Lysophospholipids; Phosphatidic Acids; Phospholipases A; Phospholipases A2; Prostaglandin Endoperoxides, Synthetic; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Stearic Acids; Thromboxane B2; Type C Phospholipases	1991
Evidence against a role of arachidonic acid metabolites in autoregulatory responses of the isolated perfused kidney of the rat. European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cytochrome P-450 Enzyme Inhibitors; Diabetes Mellitus, Experimental; Dinoprostone; In Vitro Techniques; Indomethacin; Kidney; Male; Nifedipine; Perfusion; Rats; Rats, Inbred Strains; Renal Circulation; Vascular Resistance	1991
Inhibitors of the lipoxygenase arachidonic acid pathway impair glycocholate efflux in isolated rat hepatocytes. Journal of hepatology, 1991, Volume: 12, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Cell Survival; Glycocholic Acid; In Vitro Techniques; Lipoxygenase Inhibitors; Liver; Male; Masoprocol; Oxygen Consumption; Rats; Rats, Inbred Strains	1991
Arachidonic acid-induced calcium influx in human platelets. Comparison with the effect of thrombin. The Biochemical journal, 1990, Dec-01, Volume: 272, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Biological Transport; Blood Platelets; Calcium; Carcinoma, Ehrlich Tumor; Egtazic Acid; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Fluoresceins; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; Kinetics; Manganese; Masoprocol; Mice; Neutrophils; Prostaglandin Endoperoxides, Synthetic; Rats; Spectrometry, Fluorescence; Structure-Activity Relationship; T-Lymphocytes; Thrombin	1990
Effects of anti-inflammatory and immunosuppressive drugs on the heterolamellar corneal transplantation in rabbits. Current eye research, 1990, Volume: 9, Issue:8 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Administration, Topical; Animals; Anti-Inflammatory Agents; Aqueous Humor; Arachidonic Acid; Arachidonic Acids; Cattle; Cell Count; Corneal Transplantation; Cyclosporins; Dexamethasone; Eye Proteins; Graft Rejection; Immunosuppressive Agents; Indomethacin; Inflammation; Neutrophils; Rabbits; Transplantation, Heterologous	1990
Effects of the arachidonate lipoxygenase inhibitor BW755C on traumatic and peritumoural brain oedema. Acta neurochirurgica. Supplementum, 1990, Volume: 51 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Body Water; Brain; Brain Edema; Brain Injuries; Brain Neoplasms; Cats; Female; Freezing; Lipoxygenase Inhibitors; Male	1990
A possible role of arachidonate metabolism in the mechanism of prolactin release. The American journal of physiology, 1986, Volume: 250, Issue:3 Pt 1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Cobalt; Cyclohexanones; Dopamine; Female; Ion Channels; Marine Toxins; Neurotensin; Oxocins; Penfluridol; Phospholipids; Pituitary Gland, Anterior; Prolactin; Pyrazoles; Rats; Rats, Inbred Strains; Somatostatin; Stimulation, Chemical; Thyrotropin-Releasing Hormone	1986
Effect of CI-922, a potential new antiallergy agent, on arachidonic acid metabolism in vitro. Inflammation, 1986, Volume: 10, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adult; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Azoles; Calcimycin; Cattle; Histamine Release; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indoles; Indomethacin; Leukocytes; Male; Masoprocol; Pyrazoles; Seminal Vesicles; Tetrazoles	1986
Arachidonic acid release in BW755C-pretreated rat peritoneal mast cells stimulated with A23187, concanavalin A and compound 48/80. Biochimica et biophysica acta, 1987, Feb-14, Volume: 917, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Concanavalin A; Cyclooxygenase Inhibitors; Histamine Release; In Vitro Techniques; Lipoxygenase Inhibitors; Mast Cells; p-Methoxy-N-methylphenethylamine; Pyrazoles; Rats; Rats, Inbred Strains	1987
Permeability and vasomotor response of cerebral vessels during exposure to arachidonic acid. Acta neuropathologica, 1987, Volume: 73, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Blood-Brain Barrier; Capillaries; Capillary Permeability; Cats; Cerebral Arteries; Cerebral Veins; Cerebrovascular Circulation; Dextrans; Female; Fluorescein-5-isothiocyanate; Fluoresceins; Indomethacin; Male; Microscopy, Electron; Pyrazoles; Thiocyanates; Vasomotor System	1987
High concentrations of exogenous arachidonate inhibit calcium mobilization in platelets by stimulation of adenylate cyclase. The Biochemical journal, 1988, Jul-01, Volume: 253, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenylyl Cyclases; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Calcium; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Enzyme Induction; Epoprostenol; Humans; Iloprost; In Vitro Techniques; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyrazoles; Thromboxane B2	1988
Arachidonate cannot be released directly from diacyl-sn-glycero-3-phosphocholine in thrombin-stimulated platelets. The Biochemical journal, 1989, Apr-15, Volume: 259, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Phosphatidylcholines; Pyrazoles; Rats; Thrombin	1989
Evidence of Ca2+ mobilizing action of arachidonic acid in human platelets. Biochimica et biophysica acta, 1989, Jun-15, Volume: 1012, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Aminobenzoates; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Calcium Radioisotopes; Cell Membrane; Chlorobenzoates; Cinnamates; Cyclooxygenase Inhibitors; Fatty Acids; Fatty Acids, Unsaturated; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lipid Peroxides; Lipoxygenase Inhibitors; ortho-Aminobenzoates; Phospholipases A; Phospholipases A2; Pyrazoles; Thrombin	1989
Role of arachidonic acid metabolites in acid-pepsin injury to rabbit esophagus. Gastroenterology, 1989, Volume: 97, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Esophagitis; Esophagus; Hydrogen-Ion Concentration; Indomethacin; Male; Pepsin A; Premedication; Pyrazoles; Rabbits; Sodium Chloride	1989
Increased microvascular permeability caused by toxic oxygen metabolites is partly reversed by exchanging the perfusate in isolated rat lungs. Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:7 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Capillary Permeability; Catalase; Hypoxanthines; In Vitro Techniques; Indomethacin; Lung; Male; Oxygen; Papaverine; Perfusion; Rats; Rats, Inbred Strains; Xanthine Oxidase	1989
Blockade of ADP-induced Ca2+-signal and platelet aggregation by lipoxygenase inhibitors. FEBS letters, 1989, Nov-06, Volume: 257, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Calcium; Humans; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Platelet Aggregation; Platelet Aggregation Inhibitors; Signal Transduction	1989
[Enhancement of the posttraumatic dissociation of descending influences under the suppression of arachidonic acid metabolism]. Doklady Akademii nauk SSSR, 1989, Volume: 309, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cats; Electric Stimulation; Neural Inhibition; Neural Pathways; Reflex, Monosynaptic; Spinal Cord Injuries	1989
Cytochrome P450 dependent arachidonic acid metabolism in hemopoietic cells. Advances in experimental medicine and biology, 1989, Volume: 271 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythropoiesis; Hematopoietic Stem Cells; Humans; Indomethacin; Lipoxygenase Inhibitors; Mice; NADP; Neutrophils; Pyridines	1989
Modulation of arachidonic acid metabolism has limited effects on the development of type I diabetes in animal models. Diabetes research (Edinburgh, Scotland), 1989, Volume: 12, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred BB; Sulfasalazine	1989
Complement- and IgE-mediated release of histamine from basophils in vitro. V. Differential effects of drugs modulating arachidonic acid metabolism. Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 134, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Basophils; Catechols; Complement C5; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Masoprocol; Phospholipases; Pyrazoles	1985
A neutrophil-derived cytochrome P450-dependent metabolite of arachidonic acid modulates neutrophil behavior. The American journal of pathology, 1987, Volume: 128, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Adhesion; Cell Aggregation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dogs; Leukotriene B4; Mixed Function Oxygenases; Neutrophils; Pyrazoles; Superoxides	1987
Arachidonic acid metabolites do not mediate toluene diisocyanate-induced airway hyperresponsiveness in guinea pigs. Prostaglandins, 1988, Volume: 35, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetylcholine; Airway Obstruction; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Dogs; Drug Synergism; Epoprostenol; Guinea Pigs; Indomethacin; Male; Ozone; Pyrazoles; Respiratory System; Toluene 2,4-Diisocyanate	1988
Activation by saturated and monounsaturated fatty acids of the O2- -generating system in a cell-free preparation from neutrophils. The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Membrane; Cell-Free System; Cytosol; Fatty Acids; Fatty Acids, Unsaturated; Kinetics; Lauric Acids; Lipoxygenase Inhibitors; Masoprocol; NADP; Neutrophils; Oleic Acid; Oleic Acids; Oxygen Consumption; Pyrazoles; Superoxides; Swine; Tetradecanoylphorbol Acetate	1988
The role of macrophages and eicosanoids in the pathogenesis of experimental allergic neuritis. Serial clinical, electrophysiological, biochemical and morphological observations. Brain : a journal of neurology, 1988, Volume: 111 ( Pt 5) Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Dexamethasone; Female; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Neuritis, Autoimmune, Experimental; Pyrazoles; Rats; Rats, Inbred Lew; Silicon Dioxide	1988
Growth hormone releasing factor (GRF) increases free arachidonate levels in the pituitary: a role for lipoxygenase products. Life sciences, 1986, Jan-20, Volume: 38, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Growth Hormone-Releasing Hormone; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Male; Peptide Fragments; Pituitary Gland; Pyrazoles; Quinacrine; Rats; Rats, Inbred Strains; Somatostatin	1986
Arachidonate stimulates prolactin release in vitro: a role for the fatty acid and its metabolites as intracellular regulator(s) in mammotrophs. Endocrinology, 1985, Volume: 116, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Catechols; Cells, Cultured; Female; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Oleic Acid; Oleic Acids; Phospholipases A; Phospholipases A2; Pituitary Gland; Pituitary Gland, Anterior; Prolactin; Pyrazoles; Quinacrine; Rats; Rats, Inbred Strains; Stearic Acids; Tetradecanoylphorbol Acetate	1985
Nafazatrom-induced salvage of ischemic myocardium in anesthetized dogs is mediated through inhibition of neutrophil function. Circulation research, 1985, Volume: 57, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Cell Aggregation; Coronary Disease; Dogs; Fibrinolytic Agents; Glucuronidase; Male; Myocardial Infarction; Myocardium; Neutrophils; Platelet Aggregation; Pyrazoles; Pyrazolones; Superoxides	1985
Second messenger function of arachidonic acid lipoxygenation products in human natural killer cell lysis? Scandinavian journal of immunology, 1985, Volume: 22, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Catechols; Cyclic AMP; Cyclic GMP; Cytotoxicity, Immunologic; Humans; Indomethacin; Killer Cells, Natural; Lipoxygenase; Masoprocol; Pyrazoles	1985
Involvement of cyclic AMP, iodide and metabolites of arachidonic acid in the regulation of cell proliferation of isolated porcine thyroid follicles. Molecular and cellular endocrinology, 1985, Volume: 42, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Cell Division; Colforsin; Culture Media; Culture Techniques; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Epidermal Growth Factor; Indomethacin; Insulin; Iodides; Masoprocol; Propylthiouracil; Pyrazoles; Swine; Thyroid Gland; Thyrotropin	1985
Mechanism of action of gonadotropin releasing hormone: role of lipoxygenase products of arachidonic acid in luteinizing hormone release. Journal of steroid biochemistry, 1985, Volume: 23, Issue:5B Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catechols; Cells, Cultured; Gonadotropin-Releasing Hormone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Luteinizing Hormone; Masoprocol; Pituitary Gland; Pyrazoles; Rats; SRS-A	1985
Inhibitory effect of prostaglandin E2, forskolin, and dibutyryl cAMP on arachidonic acid release and inositol phospholipid metabolism in guinea pig neutrophils. The Journal of biological chemistry, 1986, Jan-25, Volume: 261, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Catechols; Colforsin; Dinoprostone; Fatty Acids, Nonesterified; Guinea Pigs; Lysosomes; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Prostaglandins E; Pyrazoles; Superoxides	1986
Biochemical characterization of serotonin stimulated phosphoinositide turnover. Life sciences, 1986, Feb-17, Volume: 38, Issue:7 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Cerebral Cortex; Drug Synergism; Indomethacin; Phosphatidylinositols; Potassium Chloride; Protease Inhibitors; Pyrazoles; Rats; Serotonin; Tetrodotoxin; Veratrine	1986
Ketoconazole inhibits the biosynthesis of leukotrienes in vitro and in vivo. Biochemical pharmacology, 1986, Mar-15, Volume: 35, Issue:6 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bronchi; Catechols; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Ketoconazole; Leukotriene B4; Lipoxygenase Inhibitors; Male; Masoprocol; Neutrophils; Pyrazoles; Rabbits; Rats; Rats, Inbred Strains; Reticulocytes; SRS-A	1986
Leukotriene synthesis by human gastrointestinal tissues. Biochimica et biophysica acta, 1986, Sep-12, Volume: 878, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenocarcinoma; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Colonic Neoplasms; Digestive System; Dinoprostone; Gastric Mucosa; Humans; In Vitro Techniques; Intestinal Mucosa; Leukotriene B4; Masoprocol; Muscle, Smooth; Prostaglandins E; Pyrazoles; SRS-A	1986
Identification of distinct activation pathways of the human neutrophil NADPH-oxidase. Journal of immunology (Baltimore, Md. : 1950), 1986, Nov-01, Volume: 137, Issue:9 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Enzyme Activation; Humans; Indomethacin; Isoquinolines; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Phospholipids; Piperazines; Pyrazoles; Quinacrine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan	1986
Effect of AA-861, a 5-lipoxygenase inhibitor, on leukotriene synthesis in human polymorphonuclear leukocytes and on cyclooxygenase and 12-lipoxygenase activities in human platelets. Allergy, 1986, Volume: 41, Issue:7 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Blood Platelets; Calcimycin; Diethylcarbamazine; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Quinones; SRS-A	1986
Relationship of glucocorticoid suppression of arachidonic acid metabolism to alteration of neutrophil function. Journal of leukocyte biology, 1987, Volume: 41, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Dexamethasone; Diglycerides; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotriene B4; Masoprocol; Neutrophils; Phospholipids; Pyrazoles; Triglycerides; Zymosan	1987
Cytochrome P-450-dependent monooxygenase activity and endothelial-dependent relaxations induced by arachidonic acid. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Benzoflavones; beta-Naphthoflavone; Blood Vessels; Cobalt; Cytochrome P-450 Enzyme System; Drug Synergism; Endothelium; Fatty Acids; Indomethacin; Male; Methylcholanthrene; Oxygenases; Phenylephrine; Proadifen; Pulmonary Artery; Pyrazoles; Rabbits; Vasoconstriction; Vasodilation	1986
Effects of d-penicillamine, levamisole and tiopronin on eicosanoid synthesis by rat gut tissue. Agents and actions, 1986, Volume: 17, Issue:3-4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Amino Acids, Sulfur; Animals; Arachidonic Acid; Arachidonic Acids; Colon; Eicosanoic Acids; In Vitro Techniques; Levamisole; Male; Penicillamine; Pyrazoles; Rats; Rats, Inbred Strains; Tiopronin	1986
Lipoxygenase metabolites of arachidonic acid modulate hematopoiesis. Blood, 1986, Volume: 67, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Colony-Forming Units Assay; Erythrocytes; Erythropoiesis; Granulocytes; Hematopoiesis; Humans; Indomethacin; Lipoxygenase; Macrophages; Male; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Tetradecanoylphorbol Acetate	1986
Pharmacological modulation of the effects of N-formyl-L-methionyl-L-leucyl-L-phenylalanine in guinea-pigs: involvement of the arachidonic acid cascade. British journal of pharmacology, 1986, Volume: 89, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Cell Count; Blood Platelets; Bronchi; Female; Guinea Pigs; Indomethacin; Lung; Male; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Pyrazoles; Thromboxane B2	1986
Effects of inhibitors of arachidonic acid metabolism on Paf-induced gastric mucosal necrosis and haemoconcentration. British journal of pharmacology, 1986, Volume: 89, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Pressure; Dexamethasone; Gastric Mucosa; Hematocrit; Male; Necrosis; Platelet Activating Factor; Prednisolone; Pyrazoles; Rats; Rats, Inbred Strains	1986
Exaggerated atrial arachidonate metabolism in rabbit left ventricular myocardial infarction. The Journal of clinical investigation, 1987, Volume: 79, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Coronary Circulation; Coronary Vessels; Heart Atria; Indomethacin; Kinetics; Myocardial Infarction; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandins; Pyrazoles; Rabbits; SRS-A; Thromboxane B2; Vasoconstriction	1987
Effects of leukotriene D4 and antagonists of arachidonic acid metabolism and calcium entry on guinea pig tracheal muscle responsiveness. Prostaglandins, leukotrienes, and medicine, 1986, Volume: 24, Issue:2-3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium Channel Blockers; Guinea Pigs; In Vitro Techniques; Indomethacin; Muscle Contraction; Nifedipine; Potassium Chloride; Pyrazoles; SRS-A; Trachea	1986
The actions of halothane, ibuprofen and BW755C on hypoxic pulmonary vasoconstriction. Anesthesiology, 1987, Volume: 66, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Drug Interactions; Female; Halothane; Hypoxia; Ibuprofen; Lipoxygenase Inhibitors; Pulmonary Circulation; Pyrazoles; Rats; Rats, Inbred Strains; Vasoconstriction	1987
Mechanism of arachidonic acid-induced Ca2+ mobilization from rat liver microsomes. Biochimica et biophysica acta, 1987, Apr-22, Volume: 928, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Fatty Acids; In Vitro Techniques; Indomethacin; Male; Microsomes, Liver; Pyrazoles; Rats; Rats, Inbred Strains	1987
Thrombin-induced transfer of arachidonic acid in human platelets is not inhibited by trifluoperazine. Biochemical and biophysical research communications, 1987, Apr-29, Volume: 144, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Kinetics; Pyrazoles; Thrombin; Trifluoperazine	1987
Effect of inhibitors of arachidonic acid metabolism on efflux of intracellular enzymes from skeletal muscle following experimental damage. The Biochemical journal, 1987, Jan-15, Volume: 241, Issue:2 Topics: 2,4-Dinitrophenol; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Creatine Kinase; Cyclooxygenase Inhibitors; Dinitrophenols; Female; In Vitro Techniques; Masoprocol; Muscles; Muscular Diseases; Phenylacetates; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains	1987
Neomycin is a potent agent for arachidonic acid release in human platelets. Biochemical and biophysical research communications, 1987, Jul-31, Volume: 146, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Cell Membrane Permeability; Humans; Neomycin; Phospholipases A; Phospholipases A2; Pyrazoles; Saponins; Serotonin; Thrombin	1987
Oleic acid induces pulmonary injury independent of eicosanoids in the isolated, perfused rabbit lung. Circulatory shock, 1987, Volume: 22, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Fatty Acids, Unsaturated; In Vitro Techniques; Lung Compliance; Lung Diseases; Male; Oleic Acids; Organ Size; Pyrazoles; Rabbits; SRS-A; Tetrazoles	1987
Eicosanoid formation by mammalian intestine. Effects of some intestinal secretagogues. European journal of pharmacology, 1987, Jun-12, Volume: 138, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Cathartics; Colon; Eicosanoic Acids; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Intestines; Mice; Pyrazoles; Rats; Rats, Inbred Strains; Ricinoleic Acids; Species Specificity	1987
The action of erythropoietin is mediated by lipoxygenase metabolites in murine fetal liver cells. Biochemical and biophysical research communications, 1987, Aug-31, Volume: 147, Issue:1 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxyanisole; Erythropoiesis; Erythropoietin; Hydroxyeicosatetraenoic Acids; Liver; Masoprocol; Meclofenamic Acid; Mice; Phosphatidylinositols; Pyrazoles	1987
Arachidonic acid metabolites and airway epithelium-dependent relaxant factor. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Biological Products; Carbachol; Epithelium; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Pyrazoles; Trachea	1987
Effects of inhibitors of arachidonic acid metabolism on endotoxin-induced ocular inflammation. Current eye research, 1988, Volume: 7, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Arachidonic Acid; Arachidonic Acids; Clonixin; Endotoxins; Hydroxyeicosatetraenoic Acids; Indomethacin; Male; Prostaglandins; Pyrazoles; Rabbits; Uveitis	1988
Comparative effects of inhibitors of arachidonic acid metabolism on erythropoiesis. Prostaglandins, leukotrienes, and essential fatty acids, 1988, Volume: 31, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxyanisole; Cyclooxygenase Inhibitors; Erythropoiesis; Hematopoietic Stem Cells; Lipoxygenase Inhibitors; Masoprocol; Meclofenamic Acid; Mice; Pyrazoles	1988
Arachidonic acid metabolism and insulin secretion by isolated human pancreatic islets. Diabetes, 1988, Volume: 37, Issue:7 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Glucose; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase Inhibitors; Mass Spectrometry; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Pyrazoles	1988
[Inhibition of arachidonic acid-induced ear edema in the mouse with lipoxygenase-, cyclo-oxygenase- and dual inhibitors]. Die Pharmazie, 1988, Volume: 43, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Edema; In Vitro Techniques; Lipoxygenase Inhibitors; Mice; Pyrazoles	1988
Modulation of arachidonic acid metabolites and vulnerability to ventricular fibrillation during myocardial ischemia in the cat. American heart journal, 1988, Volume: 116, Issue:5 Pt 1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Cardiac Pacing, Artificial; Cats; Chromones; Coronary Disease; Female; Male; Naphthoquinones; ortho-Aminobenzoates; Pyrazoles; SRS-A; Sulfinpyrazone; Ventricular Fibrillation	1988
Inactivation of soybean lipoxygenase by lipoxygenase inhibitors in the presence of 15-hydroperoxyeicosatetraenoic acid. Biochemical pharmacology, 1988, Dec-01, Volume: 37, Issue:23 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Benzeneacetamides; Ethanol; Ethylene Glycol; Ethylene Glycols; Glycine max; Hydroxamic Acids; Leukotrienes; Linoleic Acid; Linoleic Acids; Lipid Peroxides; Lipoxygenase Inhibitors; Masoprocol; Pyrazoles	1988
Simple procedure for measuring the pharmacodynamics and analgesic potential of lipoxygenase inhibitors. Journal of pharmacological methods, 1988, Volume: 20, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipoxygenase Inhibitors; Masoprocol; Mice; Pain; Pyrazoles	1988
Effects of orpanoxin on arachidonic acid metabolism of human polymorphonuclear leucocytes and platelets in vitro. Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:7 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Chromatography, High Pressure Liquid; Female; Humans; In Vitro Techniques; Indicators and Reagents; Indomethacin; Male; Neutrophils; Propionates	1988
The effect of BW775C on respiratory distress in the rat induced by arachidonic acid. Prostaglandins, 1985, Volume: 29, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Indomethacin; Pyrazoles; Rats; Respiratory Distress Syndrome; Time Factors	1985
Arachidonic acid metabolism in isolated pancreatic islets. III. Effects of exogenous lipoxygenase products and inhibitors on insulin secretion. Biochimica et biophysica acta, 1985, Mar-27, Volume: 834, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Insulin; Insulin Secretion; Islets of Langerhans; Leukotrienes; Lipoxygenase; Male; Pyrazoles; Rats; Rats, Inbred Strains	1985
5-Hydroxyeicosatetraenoic acid increases prolactin release from rat anterior pituitary cells. Endocrinology, 1985, Volume: 116, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Female; Gallopamil; Hydroxyeicosatetraenoic Acids; Luteinizing Hormone; Penfluridol; Pituitary Gland, Anterior; Prolactin; Pyrazoles; Rats; Rats, Inbred Strains	1985
Effect of exogenous phospholipase A2 on insulin secretion from perifused rat islets. Diabetes, 1985, Volume: 34, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcium; Catechols; Cyclooxygenase Inhibitors; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase Inhibitors; Male; Masoprocol; Perfusion; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors	1985
Arachidonic acid metabolism in isolated pancreatic islets. IV. Negative ion-mass spectrometric quantitation of monooxygenase product synthesis by liver and islets. Biochimica et biophysica acta, 1985, Jun-14, Volume: 835, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Catechols; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase; Masoprocol; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxygenases; Pyrazoles; Rats; SRS-A	1985
Measurement of arachidonic acid liberation in thrombin-stimulated human platelets. Use of agents that inhibit both the cyclooxygenase and lipoxygenase enzymes. Biochimica et biophysica acta, 1985, Jul-09, Volume: 835, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Kinetics; Lipoxygenase; Lipoxygenase Inhibitors; Propyl Gallate; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Thrombin; Tritium	1985
Endothelium-dependent vasodilation by melittin: are lipoxygenase products involved? The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Bee Venoms; Catechols; Endothelium; Female; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Melitten; Muscle, Smooth, Vascular; Nitric Oxide; Phospholipases; Pyrazoles; Rabbits; Vasodilation; Vasodilator Agents	1985
Possible role of phospholipase A2 action and arachidonic acid metabolism in angiotensin II-mediated aldosterone secretion. Endocrinology, 1985, Volume: 117, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Aldosterone; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Calcium; Cattle; Cyclooxygenase Inhibitors; Dantrolene; Dose-Response Relationship, Drug; Indomethacin; Lipoxygenase Inhibitors; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Quinacrine	1985
Prostacyclin production by the deendothelialized rabbit aorta. The Journal of clinical investigation, 1985, Volume: 76, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Calcimycin; Endothelium; Epoprostenol; Indomethacin; Kinetics; Male; Pyrazoles; Rabbits	1985
Involvement of arachidonate metabolism in neurotensin-induced prolactin release in vitro. The American journal of physiology, 1985, Volume: 249, Issue:3 Pt 1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Cyclohexanones; Female; In Vitro Techniques; Kinetics; Lipoprotein Lipase; Neurotensin; Pituitary Gland; Prolactin; Pyrazoles; Quinacrine; Rats; Rats, Inbred Strains; Tritium	1985
The mechanism of the inhibitory effect of progesterone on lymphocyte cytotoxicity: II. Relationship between cytotoxicity and the cyclooxygenase pathway of arachidonic acid metabolism. American journal of reproductive immunology and microbiology : AJRIM, 1985, Volume: 9, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Cytotoxicity, Immunologic; Female; Humans; Indomethacin; Kinetics; Lipopolysaccharides; Lymphocytes; Pregnancy; Progesterone; Prostaglandin-Endoperoxide Synthases; Pyrazoles	1985
Increased metabolism of arachidonic acid in an immune model of colitis in guinea-pigs. British journal of pharmacology, 1985, Volume: 86, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Chromatography, Thin Layer; Colitis, Ulcerative; Dinitrochlorobenzene; Disease Models, Animal; Guinea Pigs; Immunization; Indomethacin; Male; Prostaglandins; Pyrazoles; Radioimmunoassay	1985
Ozone-induced bronchial hyperreactivity in guinea pigs is abolished by BW 755C or FPL 55712 but not by indomethacin. The American review of respiratory disease, 1985, Volume: 132, Issue:5 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Airway Resistance; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Bronchi; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lipoxygenase; Male; Ozone; Pyrazoles; SRS-A	1985
Platelet aggregation in whole blood: the role of thromboxane A2 and adenosine diphosphate. Thrombosis and haemostasis, 1985, Oct-30, Volume: 54, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhibitors; Epinephrine; Flurbiprofen; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Platelet Aggregation; Pyrazoles; Thrombin; Thromboxane A2; Thromboxane-A Synthase	1985
Modulation of mouse ear edema by cyclooxygenase and lipoxygenase inhibitors and other pharmacologic agents. Agents and actions, 1985, Volume: 17, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Edema; Female; Lipoxygenase Inhibitors; Methylprednisolone; Mice; Mice, Inbred Strains; Otitis Externa; Pyrazoles; Tetradecanoylphorbol Acetate	1985
Arachidonic acid and leukotriene B4 induce aggregation of human peripheral blood mononuclear leucocytes in vitro. British journal of haematology, 1984, Volume: 58, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Cell Aggregation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indomethacin; Leukocytes; Leukotriene B4; Masoprocol; Neutrophils; Pyrazoles	1984
Effects of lipoxygenase inhibitors in arachidonate-induced sudden death. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Cathepsin D; Cathepsins; Death, Sudden; Glucuronidase; Lipoxygenase Inhibitors; Liver; Lung; Lysosomes; Male; Masoprocol; Pancreas; Pyrazoles; Rabbits; Thromboxane B2	1984
On the role of arachidonic acid metabolites in mast-cell mediated mitogenesis in the rat. Virchows Archiv. B, Cell pathology including molecular pathology, 1984, Volume: 46, Issue:1-2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; DNA; Histamine; Indomethacin; Lipoxygenase Inhibitors; Male; Mast Cells; Mesentery; Mitosis; p-Methoxy-N-methylphenethylamine; Phospholipases A; Phospholipases A2; Prostaglandins; Pyrazoles; Quinacrine; Rats; Rats, Inbred Strains; SRS-A	1984
In vivo and in vitro effects of arachidonic acid products on liver cell integrity following carbon tetrachloride poisoning. Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 12 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alanine Transaminase; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbon Tetrachloride Poisoning; Epoprostenol; Female; Indomethacin; Liver; Lysine; Peroxides; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains	1983
Inhibition of tissue damage by the arachidonate lipoxygenase inhibitor BW755C. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:9 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Dexamethasone; Foreign-Body Reaction; Indomethacin; Inflammation; Leukocytes; Leukotriene B4; Male; Pyrazoles; Rats; SRS-A	1984
Biosynthesis of lipoxygenase products by ocular tissues. Experimental eye research, 1983, Volume: 36, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cats; Conjunctiva; Dogs; Guinea Pigs; Haplorhini; Indomethacin; Iris; Lipoxygenase; Pyrazoles; Rabbits	1983
Selective inhibition of the lipoxygenase metabolic pathway of arachidonic acid by the SRS-A antagonist, FPL 55712. Prostaglandins, 1983, Volume: 25, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromones; Cyclooxygenase Inhibitors; Indomethacin; Lipoxygenase Inhibitors; Pyrazoles; Rats; SRS-A	1983
A rapid method for detecting inhibitors of both cyclo-oxygenase lipoxygenase metabolites of arachidonic acid. Journal of pharmacological methods, 1983, Volume: 9, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Biotransformation; Calcimycin; Catechols; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Neutrophils; Oxygenases; Propionates; Pyrazoles	1983
Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa. Gut, 1983, Volume: 24, Issue:12 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colitis, Ulcerative; Colon; Humans; Indomethacin; Intestinal Mucosa; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Thromboxane B2	1983
Role of leukocytes in acute myocardial infarction in anesthetized dogs: relationship to myocardial salvage by anti-inflammatory drugs. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:2 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anesthesia; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Dexamethasone; Dogs; Hydroxyurea; Indomethacin; Lymphocyte Activation; Male; Myocardial Infarction; Myocardium; Neutrophils; Pyrazoles	1984
Arachidonic acid metabolism and thyrotropin secretion in vitro. European journal of pharmacology, 1984, Feb-10, Volume: 98, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Female; In Vitro Techniques; Indomethacin; Masoprocol; Phospholipases A; Phospholipases A2; Pituitary Gland; Pyrazoles; Quinacrine; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin; Thyrotropin-Releasing Hormone	1984
Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations. Inflammation, 1984, Volume: 8, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Neutrophils; Pyrazoles; Quercetin; Rats	1984
Human and murine natural killer cell activity may require lipoxygenation of arachidonic acid. The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:3 Pt 2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Antibody-Dependent Cell Cytotoxicity; Antioxidants; Arachidonic Acid; Arachidonic Acids; Catechols; Cell Line; Humans; Indomethacin; Killer Cells, Natural; Leukemia, Myeloid, Acute; Masoprocol; Pyrazoles	1984
Effect of inhibitors of the lipoxygenase pathway on mouse myoblast fusion. Experimental cell research, 1984, Volume: 155, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Fusion; Cells, Cultured; Cyclooxygenase Inhibitors; Indomethacin; Lipoxygenase Inhibitors; Mice; Muscles; Pyrazoles; Umbelliferones	1984
The effect of arachidonic acid metabolism on intravascular platelet aggregation in rats. Thrombosis research, 1984, Oct-15, Volume: 36, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Chromatography, Thin Layer; Collagen; Indomethacin; Piroxicam; Platelet Aggregation; Propionates; Pyrazoles; Radioimmunoassay; Rats; Thiazines; Thromboxane B2	1984
Arachidonic acid-induced human platelet aggregation independent of cyclooxygenase and lipoxygenase. Prostaglandins, 1984, Volume: 28, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium Chloride; Humans; Indomethacin; L-Lactate Dehydrogenase; Lipoxygenase; Microscopy, Electron; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Serotonin	1984
Possible involvement of lipoxygenase products of arachidonic acid pathway in ovulation. Prostaglandins, 1983, Volume: 26, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Chromones; Fatty Acids, Unsaturated; Female; Lipoxygenase Inhibitors; Masoprocol; Ovulation; Pyrazoles; Rats; Rats, Inbred Strains	1983
Evidence against a role for lipoxygenase-derived products of arachidonic acid in the lamb ductus arteriosus. Canadian journal of physiology and pharmacology, 1982, Volume: 60, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Chromones; Ductus Arteriosus; Female; Lipoxygenase; Muscle Contraction; Pregnancy; Pyrazoles; Sheep; SRS-A	1982
Effect of ETYA and BW 755c on arachidonate-induced contractions in the guinea-pig isolated trachea. British journal of pharmacology, 1982, Volume: 76, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Drug Interactions; Fatty Acids, Unsaturated; Guinea Pigs; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Pyrazoles; Trachea	1982
The influence of some 3-amino-2-pyrazoline derivatives on cyclooxygenase and lipoxidase activities. Biochemical pharmacology, 1982, Jun-01, Volume: 31, Issue:11 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Horses; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Microsomes; Oxygen Consumption; Prostaglandins; Pyrazoles; Seminal Vesicles; Sheep	1982
Lipoxygenation of arachidonic acid: a pivotal step in stimulus-secretion coupling in the pancreatic beta cell. Endocrinology, 1982, Volume: 111, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Arachidonic Acids; Catechols; Islets of Langerhans; Lipoxygenase Inhibitors; Masoprocol; Pyrazoles; Tolbutamide	1982
Interdependence of contractile responses of rat small mesenteric arteries on nitric oxide and cyclo-oxygenase and lipoxygenase products of arachidonic acid. British journal of pharmacology, 1994, Volume: 112, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetylcholine; Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Arginine; Cholic Acids; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar	1994
Roles of prostaglandin production and mitogen-activated protein kinase activation in hepatocyte growth factor-mediated rat hepatocyte proliferation. Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cells, Cultured; DNA; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; Indomethacin; Kinetics; Liver; Male; Phospholipases A; Phospholipases A2; Phosphotyrosine; Prostaglandins; Rats; Rats, Wistar; Tyrosine	1995
Relative roles of nitric oxide and cyclo-oxygenase and lipoxygenase products of arachidonic acid in the contractile responses of rat renal arcuate arteries. British journal of pharmacology, 1994, Volume: 112, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetylcholine; Animals; Arachidonic Acid; Arginine; Arteries; Cholic Acids; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Renal Circulation	1994
Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat. British journal of pharmacology, 1993, Volume: 110, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antioxidants; Arachidonic Acid; Arthus Reaction; Carrageenan; Colchicine; Cyclooxygenase Inhibitors; Deferoxamine; Dexamethasone; Edema; Lipoxygenase Inhibitors; Male; Peroxidase; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase	1993
Formation, metabolism, and action of hepoxilin A3 in the rat pineal gland. Journal of neurochemistry, 1994, Volume: 62, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 8,11,14-Eicosatrienoic Acid; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arachidonic Acid; Cells, Cultured; Cyclic AMP; Gas Chromatography-Mass Spectrometry; Male; Pineal Gland; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tritium	1994
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells. The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate	1993
Effects of eicosanoid metabolism inhibitors on growth of a human gastric tumour cell line (HGT). Cancer letters, 1993, Sep-15, Volume: 73, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Aspirin; Cell Division; Eicosanoids; Fatty Acids; Humans; Masoprocol; Membrane Lipids; Phospholipids; Stomach Neoplasms; Tumor Cells, Cultured	1993
Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia. The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Calcium; Carbon Radioisotopes; Cell Hypoxia; Endothelium, Vascular; Humans; Indomethacin; Kinetics; Oxygen; Phospholipases A; Phospholipases A2; Prostaglandins; Quinacrine; Stearic Acids; Tritium; Umbilical Veins; Verapamil	1993
Role of endothelium-derived metabolites of arachidonic acid in enhanced pulmonary artery contractions in female rabbits. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:1 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Methacholine Chloride; Potassium Chloride; Pulmonary Artery; Rabbits; Sex Characteristics; Thromboxane B2; Vasoconstriction	1996
Clearance and metabolism of arachidonic acid by C6 glioma cells and astrocytes. Neurochemical research, 1995, Volume: 20, Issue:12 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Astrocytes; Culture Media; Cyclooxygenase Inhibitors; Dinoprost; Glioma; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; Tumor Cells, Cultured	1995
Effects of arachidonic acid metabolism on hypoxic vasoconstriction in rabbit lungs. European journal of pharmacology, 1998, Sep-04, Volume: 356, Issue:2-3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Aspirin; Cyclooxygenase Inhibitors; Drug Interactions; Female; Hypoxia; Indoles; Lipoxygenase Inhibitors; Lung; Male; Masoprocol; Rabbits; Vasoconstriction	1998
Arachidonic acid, but not its metabolites, is essential for FcgammaR-stimulated intracellular killing of Staphylococcus aureus by human monocytes. Immunology, 1999, Volume: 96, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetophenones; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Immunoglobulin G; Indomethacin; Lipoxygenase Inhibitors; Monocytes; Oxygen; Phagocytosis; Phospholipases A; Phospholipases A2; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, IgG; Staphylococcus aureus; Sulfonamides	1999
The influence of certain arachidonic acid pathway inhibitors on central nervous system catecholamine level in rats administered with ethanol. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1998, Volume: 53 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Benzoquinones; Brain; Dopamine; Enzyme Inhibitors; Ethanol; Imidazoles; Male; Norepinephrine; Pyridines; Rats; Rats, Wistar	1998
Mechanisms of arachidonic acid induced glial swelling. Brain research. Molecular brain research, 2000, Mar-29, Volume: 76, Issue:2 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Amiloride; Animals; Arachidonic Acid; Brain Edema; Cell Size; Enzyme Inhibitors; Glioma; Models, Neurological; Neuroglia; Ouabain; Superoxide Dismutase; Tumor Cells, Cultured	2000
Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils. Journal of leukocyte biology, 2001, Volume: 69, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Androstadienes; Animals; Arachidonic Acid; Arachidonic Acids; Butadienes; Calcium; Carbazoles; Chelating Agents; Chromones; Cyclooxygenase Inhibitors; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Indoles; Lipoxygenase Inhibitors; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neutrophils; Nitriles; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin	2001
Antioxidant activity of the methanol fraction of Pluchea indica root extract. Phytotherapy research : PTR, 2002, Volume: 16, Issue:4 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Asteraceae; Carbon Tetrachloride; Edema; Free Radical Scavengers; Glucose Oxidase; Hydrogen Peroxide; Hydroxyl Radical; Inflammation; Lipid Peroxidation; Lipoxygenase; Methanol; Mice; Phytotherapy; Plant Extracts; Plant Roots; Pyrazoles; Superoxides; Vitamin E	2002
Pharmacological studies on Indian black tea (leaf variety) in acute and chronic inflammatory conditions. Phytotherapy research : PTR, 2008, Volume: 22, Issue:6 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetic Acid; Acute Disease; Animals; Arachidonic Acid; Arthritis, Experimental; Chronic Disease; Edema; Inflammation; Lipopolysaccharides; Male; Plant Extracts; Plant Leaves; Rats; Tea	2008