Compounds > bw 58c
Page last updated: 2024-09-04

bw 58c and naphthoquinones

bw 58c has been researched along with naphthoquinones in 6 studies

Compound Research Comparison

Studies
(bw 58c)		Trials
(bw 58c)		Recent Studies (post-2010)
(bw 58c)		Studies
(naphthoquinones)		Trials
(naphthoquinones)		Recent Studies (post-2010) (naphthoquinones)
6007,1101492,923

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dickins, M; Ginger, CD; Gutteridge, WE; Holdich, T; Hudson, AT; Hutchinson, DB; Latter, VS; Pudney, M; Randall, AW1
Astbury, PJ; Morgan, RJ; Parsons, DN; Port, CJ; Read, NG1
Burchell, JR; Hammond, DJ; Pudney, M1
Warhurst, DC1
Burke, MD; Dickins, M; Weaver, RJ2

Reviews

1 review(s) available for bw 58c and naphthoquinones

ArticleYear
New drugs and their potential use against drug-resistant malaria.
    Annali dell'Istituto superiore di sanita, 1985, Volume: 21, Issue:3

    Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Mice; Naphthoquinones; Plasmodium falciparum; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine

1985

Other Studies

5 other study(ies) available for bw 58c and naphthoquinones

ArticleYear
566C80: a potent broad spectrum anti-infective agent with activity against malaria and opportunistic infections in AIDS patients.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:9

    Topics: 4-Quinolones; Acquired Immunodeficiency Syndrome; Adult; Animals; Anti-Infective Agents; Antimalarials; Aotus trivirgatus; Atovaquone; Dogs; Humans; Malaria, Falciparum; Male; Microsomes, Liver; Middle Aged; NADP; Naphthoquinones; Opportunistic Infections; Plasmodium; Rats; Toxoplasma

1991
Induction and exacerbation of hyaline droplet formation in the proximal tubular cells of the kidneys from male rats receiving a variety of pharmacological agents.
    Toxicology, 1988, Nov-14, Volume: 52, Issue:1-2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Female; Kidney Tubules, Proximal; Levamisole; Male; Naphthalenes; Naphthoquinones; Pyrazoles; Rats; Rats, Inbred Strains

1988
Inhibition of pyrimidine biosynthesis de novo in Plasmodium falciparum by 2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone in vitro.
    Molecular and biochemical parasitology, 1985, Volume: 14, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antimalarials; Bicarbonates; Naphthoquinones; Plasmodium falciparum; Pyrimidines; Uridine Triphosphate

1985
Hydroxylation of the antimalarial drug 58C80 by CYP2C9 in human liver microsomes: comparison with mephenytoin and tolbutamide hydroxylations.
    Biochemical pharmacology, 1995, Mar-30, Volume: 49, Issue:7

    Topics: Antimalarials; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Kinetics; Mephenytoin; Microsomes, Liver; Naphthoquinones; Steroid 16-alpha-Hydroxylase; Tolbutamide

1995
Cytochrome P450 2C9 is responsible for hydroxylation of the naphthoquinone antimalarial drug 58C80 in human liver.
    Biochemical pharmacology, 1993, Oct-05, Volume: 46, Issue:7

    Topics: Amino Acid Sequence; Animals; Antimalarials; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Female; Humans; Hydroxylation; Isoenzymes; Male; Microsomes, Liver; Molecular Sequence Data; Naphthoquinones; Rats; Rats, Sprague-Dawley; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

1993