bw 373u86 has been researched along with morphine in 10 studies
| Studies (bw 373u86) | Trials (bw 373u86) | Recent Studies (post-2010) (bw 373u86) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 80 | 0 | 4 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | bw 373u86 (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bishop, MJ; Boswell, GE; Chang, KJ; Collins, MA; Garrido, DM; Harris, PA; McNutt, RW; O'Neill, SJ; Wei, K | 1 |
| Adams, JU; Adler, MW; Chen, XH; DeRiel, JK; Geller, EB; Liu-Chen, LY | 1 |
| Moerschbaecher, JM; Pakarinen, ED; Woods, JH | 1 |
| Chang, KJ; Comer, SD; De Costa, BR; McNutt, RW; Mosberg, HI; Woods, JH | 1 |
| Chang, KJ; Lee, PH; McNutt, RW | 1 |
| Cook, CD; Morgan, D; Negus, SS; Picker, MJ | 1 |
| Fiore, P; Gannon, RL; Tierno, A | 1 |
| Gross, ER; Gross, GJ; Hsu, AK | 2 |
| Bradbury, FA; Traynor, JR; Zelnik, JC | 1 |
10 other study(ies) available for bw 373u86 and morphine
| Article | Year |
|---|---|
3-(alphaR)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N-alkyl-N-arylbenzamides: potent, non-peptidic agonists of both the micro and delta opioid receptors.
Topics: Animals; Benzamides; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship; Vas Deferens | 2003 |
An antisense oligodeoxynucleotide to mu-opioid receptors inhibits mu-opioid receptor agonist-induced analgesia in rats.
Topics: Analgesia; Analgesics; Analysis of Variance; Animals; Base Sequence; Benzamides; Cerebrospinal Fluid; Endorphins; Injections, Intraventricular; Injections, Subcutaneous; Male; Molecular Sequence Data; Morphine; Oligonucleotides, Antisense; Piperazines; Pyrrolidines; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1995 |
Repeated acquisition of behavioral chains in squirrel monkeys: comparisons of a mu, kappa and delta opioid agonist.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzamides; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Morphine; Naltrexone; Piperazines; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri | 1995 |
Discriminative stimulus effects of BW373U86: a nonpeptide ligand with selectivity for delta opioid receptors.
Topics: Amino Acid Sequence; Analgesics; Animals; Benzamides; Benzomorphans; Columbidae; Discrimination Learning; Enkephalin, Leucine; Molecular Sequence Data; Morphine; Naltrexone; Narcotic Antagonists; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, mu | 1993 |
A nonpeptidic delta opioid receptor agonist, BW373U86, attenuates the development and expression of morphine abstinence precipitated by naloxone in rat.
Topics: Animals; Benzamides; Injections, Subcutaneous; Male; Morphine; Morphine Dependence; Naloxone; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Substance Withdrawal Syndrome; Time Factors | 1993 |
Effects of the delta opioid against BW373U86 in pigeons trained to discriminate fentanyl, bremazocine and water in a three-choice drug discrimination procedure.
Topics: Analgesics; Animals; Benzamides; Benzomorphans; Columbidae; Discrimination, Psychological; Female; Fentanyl; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Piperazines; Receptors, Opioid, delta | 1996 |
Delta opioid inhibition of light-induced phase advances in hamster circadian activity rhythms.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzamides; Biological Clocks; Circadian Rhythm; Cricetinae; Enkephalins; Light; Male; Mesocricetus; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Opioid Peptides; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Suprachiasmatic Nucleus | 2002 |
Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts.
Topics: Aminophenols; Androstadienes; Animals; Benzamides; Cardiotonic Agents; Chromones; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Male; Maleimides; Morphine; Morpholines; Myocardial Infarction; Narcotic Antagonists; Nuclear Receptor Subfamily 1, Group F, Member 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Premedication; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Signal Transduction; Sirolimus; Wortmannin | 2004 |
GSK3beta inhibition and K(ATP) channel opening mediate acute opioid-induced cardioprotection at reperfusion.
Topics: Analgesics, Opioid; Androstadienes; Animals; Benzamides; Benzopyrans; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanidines; Heart Rate; Imidazoles; Indoles; Ion Channel Gating; Male; Maleimides; Morphine; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Sarcolemma; Signal Transduction; Time Factors; Wortmannin | 2007 |
G protein independent phosphorylation and internalization of the delta-opioid receptor.
Topics: Analgesics, Opioid; Arrestins; Benzamides; beta-Arrestin 2; beta-Arrestins; Cell Line, Transformed; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Green Fluorescent Proteins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Morphine; Oligopeptides; Pertussis Toxin; Phosphorylation; Piperazines; Protein Binding; Protein Transport; Quinolines; Receptors, Opioid, delta; Serine; Sulfur Isotopes; Transfection | 2009 |