bw 373u86 has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 6 studies
| Studies (bw 373u86) | Trials (bw 373u86) | Recent Studies (post-2010) (bw 373u86) | Studies (enkephalin, ala(2)-mephe(4)-gly(5)-) | Trials (enkephalin, ala(2)-mephe(4)-gly(5)-) | Recent Studies (post-2010) (enkephalin, ala(2)-mephe(4)-gly(5)-) |
|---|---|---|---|---|---|
| 80 | 0 | 4 | 151 | 0 | 71 |
| 80 | 0 | 4 | 2,727 | 1 | 374 |
| Protein | Taxonomy | bw 373u86 (IC50) | enkephalin, ala(2)-mephe(4)-gly(5)- (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.003 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 1.2415 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0132 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.004 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.0014 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0048 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0283 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burgess, JP; Carroll, FI; Dersch, CM; Herault, XM; Horel, RB; Mascarella, SW; Rothman, RB; Thomas, JB; Xu, H | 1 |
| Atkinson, RN; Carroll, FI; Dersch, CM; Herault, XM; Horel, RB; Mascarella, SW; Rothman, RB; Thomas, JB; Xu, H | 1 |
| Atkinson, RN; Burgess, JP; Carroll, FI; Dersch, CM; Flippen-Anderson, JL; George, CF; Herault, XM; Mascarella, SW; Rothman, RB; Thomas, JB; Xu, H | 1 |
| Becketts, K; Bilsky, EJ; Calderon, SN; Davis, P; Flippen-Anderson, JL; Horvath, R; Kayakiri, H; Porreca, F; Rice, KC; Rothman, RB; Smith, LE; Xu, H | 1 |
| Han, JS; Wang, XM; Wang, Y | 1 |
| Ballard, ME; Harmon, AC; Holtzman, SG; White, DA | 1 |
6 other study(ies) available for bw 373u86 and enkephalin, ala(2)-mephe(4)-gly(5)-
| Article | Year |
|---|---|
(+/-)-4-[(N-allyl-cis-3-methyl-4-piperidinyl)phenylamino]-N,N-diethylbenzamide displays selective binding for the delta opioid receptor.
Topics: Benzamides; Piperazines; Piperidines; Radioligand Assay; Receptors, Opioid, delta | 1999 |
Optically pure (-)-4-[(N-allyl-3-methyl-4-piperidinyl)phenyl-amino]-N,N-diethylbenzami de displays selective binding and full agonist activity for the delta opioid receptor.
Topics: Benzamides; Brain; Piperidines; Radioligand Assay; Receptors, Opioid, delta | 1999 |
Factors influencing agonist potency and selectivity for the opioid delta receptor are revealed in structure-activity relationship studies of the 4-[(N-substituted-4-piperidinyl)arylamino]-N,N-diethylbenzamides.
Topics: Animals; Benzamides; Brain; Crystallography, X-Ray; Guinea Pigs; In Vitro Techniques; Ligands; Piperazines; Piperidines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship | 2001 |
Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80)
Topics: Animals; Benzamides; Binding, Competitive; Brain; Crystallography, X-Ray; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Vas Deferens | 1997 |
Discrimination between peptide and non-peptide opioid agonists on the transcription of opioid receptors in two cell lines.
Topics: Benzamides; Cell Line; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Piperazines; Polymerase Chain Reaction; Receptors, Opioid, delta; Receptors, Opioid, mu; RNA, Messenger; Transcription, Genetic | 2001 |
Acute delta- and kappa-opioid agonist pretreatment potentiates opioid antagonist-induced suppression of water consumption.
Topics: Analgesics, Opioid; Animals; Benzamides; Benzomorphans; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Water Deprivation | 2008 |