bw 245c has been researched along with prostaglandin d2 in 52 studies
| Studies (bw 245c) | Trials (bw 245c) | Recent Studies (post-2010) (bw 245c) | Studies (prostaglandin d2) | Trials (prostaglandin d2) | Recent Studies (post-2010) (prostaglandin d2) |
|---|---|---|---|---|---|
| 96 | 3 | 10 | 3,454 | 78 | 751 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (19.23) | 18.7374 |
| 1990's | 15 (28.85) | 18.2507 |
| 2000's | 19 (36.54) | 29.6817 |
| 2010's | 8 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abramovitz, M; Boie, Y; Metters, KM; Sawyer, N; Slipetz, DM | 1 |
| Hirata, M; Kiriyama, M; Kobayashi, T; Narumiya, S; Sugimoto, Y; Ushikubi, F | 1 |
| Abramovitz, M; Ford-Hutchinson, AW; Metters, KM; Wright, DH | 1 |
| Ford-Hutchinson, AW; Metters, KM; Nantel, F; Wright, DH | 1 |
| Azuma, I; Goh, Y; Hayaishi, O; Nakajima, M | 1 |
| Church, MK; Featherstone, RL; Holgate, ST; Robinson, C | 1 |
| Hawley, SB; Nieves, AL; Protzman, CE; Ralston, TR; Spada, CS; Williams, LS; Woodward, DF | 1 |
| Keery, RJ; Lumley, P | 1 |
| Collins, BA; Kelly, MG; Robertson, AD; Trist, DG; Wood, J | 1 |
| Hamid-Bloomfield, S; Whittle, BJ | 1 |
| Hamid, S; Lidbury, P; Rosam, AC; Whittle, BJ | 1 |
| Bolofo, ML; Giles, H; Kelly, MG; Leff, P; Robertson, AD | 1 |
| Hamid, S; Whittle, BJ | 1 |
| Narumiya, S; Toda, N | 1 |
| Andersen, NH; Hanson, SR; Harker, LA; Tynan, SS; Wills, MT | 1 |
| Casals-Stenzel, J; Schillinger, E; Town, MH | 1 |
| Moncada, S; Mullane, K; Vane, JR; Whittle, BJ | 1 |
| Betti, PA; Prior, ET; Rangachari, PK; Roberts, LJ | 1 |
| Crankshaw, D; Fernandes, B | 1 |
| Lawrence, RA; Woodward, DF | 1 |
| Leff, P; Lydford, SJ; McKechnie, KC | 1 |
| Eguchi, N; Hayaishi, O; Ito, S; Kanaoka, Y; Minami, T; Nagata, A; Shirafuji, N; Tanaka, T; Urade, Y; Yoshida, N | 1 |
| Brink, C; de Montpreville, V; Gascard, JP; Labat, C; Norel, X; Walch, L | 1 |
| Brink, C; Dulmet, E; Gascard, JP; Labat, C; Norel, X; Walch, L | 1 |
| Chan, CL; Lau, HY | 1 |
| Chan, CL; Jones, RL; Lau, HY | 1 |
| Ajuebor, MN; Singh, A; Wallace, JL | 1 |
| Angeli, V; Capron, A; Capron, M; Faveeuw, C; Fontaine, J; Roye, O; Teissier, E; Trottein, F; Wolowczuk, I | 1 |
| Cao, J; Kitazawa, T; Shayibuzhati, M; Tajima, T; Taneike, T | 1 |
| Heinemann, A; Holzer, P; Peskar, BA; Shahbazian, A | 1 |
| DeMasi, GM; Hardwick, JC; Jelson, GS; Sager, KL | 1 |
| de Heer, HJ; Hammad, H; Hoogsteden, HC; Lambrecht, BN; Soullie, T; Trottein, F | 1 |
| Azuma, Y; Daito, M; Date, M; Ohura, K; Watanabe, K | 1 |
| Bacon, KB; Hirai, K; Iikura, M; Ishii, A; Matsushima, K; Nagase, H; Shichijo, M; Yamaguchi, M; Yamamoto, K; Yoshimura-Uchiyama, C | 1 |
| Andreasson, K; Hand, T; Liang, X; Wu, L | 1 |
| Gazi, L; Gyles, SL; Hunter, MG; Pettipher, R; Townsend, E; Wettey, FR; Xue, L | 1 |
| Cheng, K; Gottesdiener, K; Lai, E; Metters, K; O'Neill, G; Sturino, C; Wang, Z; Waters, MG; Wright, SD; Wu, KK; Wu, TJ | 1 |
| de Brum-Fernandes, AJ; Doré, S; Maruyama, T; Narumiya, S; Saleem, S; Zhuang, H | 1 |
| Andreasson, K; Liang, X; Wang, Q; Wu, L | 1 |
| Araldi, GL; Brugger, N; Kim, NN; Palmer, SS; Traish, AM | 1 |
| Capron, M; Faveeuw, C; Fontaine, J; Gosset, P; Mallevaey, T; Maruyama, T; Matsuoka, T; Narumiya, S; Paget, C; Torres, D; Trottein, F | 1 |
| Heinemann, A; Peskar, BA; Prenn, C; Schuligoi, R | 1 |
| Cisowski, J; Dulak, J; Jozkowicz, A; Kotlinowski, J; Mleczko, K; Taha, H; Was, H; Weigel, G | 1 |
| Furuta, K; Hokamura, K; Ibaraki, K; Maeda, M; Suzuki, M; Thura, M; Umemura, K; Yamamoto, S | 1 |
| Baglole, CJ; Feldon, SE; Guo, N; O'Loughlin, CW; Phipps, RP | 1 |
| Alcaraz, MJ; Ferrándiz, ML; Ibáñez, L; Maicas, N; Úbeda, A | 1 |
| Bell, K; Heinemann, A; Kostenis, E; Platzer, W; Schröder, R; Sedej, M; Vukoja, A; Waldhoer, M | 1 |
| Doi, H; Egawa, G; Hirabayashi, T; Kabashima, K; Miyachi, Y; Murakami, M; Nakahigashi, K; Otsuka, A; Tanizaki, H; Urade, Y; Zouboulis, CC | 1 |
| Devillier, P; Grassin-Delyle, S; Mechiche, H; Nazeyrollas, P; Robinet, A | 1 |
| Ayabe, S; Hori, M; Kida, T; Murata, T; Ozaki, H | 1 |
| Wu, X; Yu, S; Zhang, S | 1 |
| Arai, T; Awata, A; Fujino, H; Murayama, T; Okura, I; Oyama, S; Regan, JW; Yamazaki, R | 1 |
1 review(s) available for bw 245c and prostaglandin d2
| Article | Year |
|---|---|
Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin E1 and D2 on platelets.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Membrane; Epoprostenol; Humans; Hydantoins; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Prostaglandins, Synthetic; Radioligand Assay; Receptors, Epoprostenol; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Species Specificity; Structure-Activity Relationship | 1985 |
1 trial(s) available for bw 245c and prostaglandin d2
| Article | Year |
|---|---|
Effects of prostaglandin D2 and its analogue, BW245C, on intraocular pressure in humans.
Topics: Administration, Topical; Adult; Conjunctiva; Double-Blind Method; Female; Humans; Hydantoins; Hyperemia; Intraocular Pressure; Male; Prostaglandin D2; Pruritus; Tonometry, Ocular | 1991 |
50 other study(ies) available for bw 245c and prostaglandin d2
| Article | Year |
|---|---|
Molecular cloning and characterization of the human prostanoid DP receptor.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Calcium; Cells, Cultured; Cloning, Molecular; Cyclic AMP; Humans; Molecular Sequence Data; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin | 1995 |
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
Topics: Animals; CHO Cells; Cricetinae; Ligands; Mice; Prostaglandins; Receptors, Prostaglandin; Transfection | 1997 |
Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist.
Topics: Adenine Nucleotides; Benzoates; Binding, Competitive; Cell Line; Cyclic AMP; Dinoprostone; Guanine Nucleotides; Humans; Kinetics; Receptors, Immunologic; Receptors, Prostaglandin; Recombinant Proteins; Thiazoles; Thiazolidines; Tritium | 1998 |
A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Epitopes; Gene Expression; Humans; In Situ Hybridization; Molecular Sequence Data; Oligopeptides; Peptides; Prostaglandin D2; Radioligand Assay; Rats; Receptors, Immunologic; Receptors, Prostaglandin; Recombinant Fusion Proteins; RNA Probes; RNA, Messenger; Sequence Homology, Amino Acid; Tissue Distribution | 1999 |
Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9 alpha,11 beta-PGF2 and PGF2 alpha.
Topics: Animals; Biphenyl Compounds; Bronchi; Dinoprost; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Humans; Hydantoins; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin D2; Prostaglandins, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxanes; Trachea | 1990 |
Studies on the ocular pharmacology of prostaglandin D2.
Topics: Animals; Aqueous Humor; Capillary Permeability; Chemotaxis, Leukocyte; Conjunctiva; Dinoprost; Eosinophils; Evans Blue; Eye; Female; Guinea Pigs; Hydantoins; Inflammation; Intraocular Pressure; Male; Prostaglandin D2; Rabbits | 1990 |
AH6809, a prostaglandin DP-receptor blocking drug on human platelets.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Dinoprost; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Receptors, Immunologic; Receptors, Prostaglandin; Xanthenes; Xanthones | 1988 |
The antagonism by BW A868C of PGD2 and BW245C activation of human platelet adenylate cyclase.
Topics: Adenylyl Cyclases; Blood Platelets; Enzyme Activation; Epoprostenol; Humans; Hydantoins; Iloprost; In Vitro Techniques; Platelet Aggregation; Prostaglandin D2; Receptors, Prostaglandin | 1989 |
Antagonism of PGD2 vasodepressor responses in the rat in vivo by the novel, selective antagonist, BW A868C.
Topics: Animals; Blood Pressure; Epoprostenol; Hydantoins; Infusions, Intravenous; Male; Prostaglandin D2; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Sulfonamides | 1989 |
The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; Blood Vessels; Guinea Pigs; Humans; Hydantoins; In Vitro Techniques; Jugular Veins; Male; Muscle Contraction; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Prostaglandin; Sulfonamides; Trachea | 1989 |
Interaction of prostaglandin D2 with prostacyclin, carbacyclin and the hydantoin prostaglandin, BW245C, in guinea-pig platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Bucladesine; Colforsin; Diterpenes; Drug Interactions; Epoprostenol; Guinea Pigs; Hydantoins; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin D2; Prostaglandins D | 1985 |
Different responsiveness of prostaglandin D2-sensitive systems to prostaglandin D2 and its analogues.
Topics: Animals; Cerebral Arteries; Cyclic AMP; Dogs; Guinea Pigs; Humans; Hydantoins; Mast Cells; Muscle Contraction; Muscle Relaxation; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Rabbits; Rats; Rats, Inbred Strains; Stomach; Trachea | 1985 |
On the multiplicity of platelet prostaglandin receptors. II. The use of N-0164 for distinguishing the loci of action for PGI2, PGD2, PGE2 and hydantoin analogs.
Topics: Blood Platelets; Dinoprostone; Epoprostenol; Humans; Hydantoins; Organophosphonates; Organophosphorus Compounds; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Receptors, Cell Surface; Receptors, Prostaglandin; Structure-Activity Relationship | 1984 |
Pharmacological and cardiovascular properties of a hydantoin derivative, BW 245 C, with high affinity and selectivity for PGD2 receptors.
Topics: Animals; Blood Platelets; Blood Pressure; Cattle; Female; Heart Rate; Hemodynamics; Humans; Hydantoins; Hypertension; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Rats; Receptors, Cell Surface; Receptors, Prostaglandin; Subcellular Fractions; Thromboxanes; Uterus | 1983 |
Platelet and cardiovascular activity of the hydantoin BW245C, a potent prostaglandin analogue.
Topics: Animals; Arteries; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Female; Gastric Juice; Gastric Mucosa; Horses; Humans; Hydantoins; Male; Platelet Aggregation; Prostaglandin D2; Prostaglandins; Prostaglandins D; Rabbits; Rats; Rats, Inbred Strains; Sheep; Species Specificity; Structure-Activity Relationship | 1983 |
Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: an argument for a different DP receptor?
Topics: Animals; Colon; Dogs; Electrophysiology; Female; Hydantoins; In Vitro Techniques; Intestinal Mucosa; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin | 1995 |
Functional characterization of the prostanoid DP receptor in human myometrium.
Topics: Adult; Dinoprost; Dose-Response Relationship, Drug; Female; Humans; Hydantoins; Hysterectomy; Middle Aged; Muscle Contraction; Muscle, Smooth; Myometrium; Prostaglandin D2; Prostanoic Acids; Receptors, Prostaglandin | 1995 |
Identification of a single (FP) receptor associated with prostanoid-induced Ca2+ signals in Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Binding, Competitive; Calcium; Dinoprostone; Hydantoins; Mice; Prostaglandin D2; Prostaglandins F; Prostaglandins F, Synthetic; Receptors, Prostaglandin; Second Messenger Systems | 1994 |
Interaction of BW A868C, a prostanoid DP-receptor antagonist, with two receptor subtypes in the rabbit isolated saphenous vein.
Topics: Animals; Anti-Arrhythmia Agents; Biphenyl Compounds; Dinoprostone; Dose-Response Relationship, Drug; Hydantoins; Male; Potassium Chloride; Prostaglandin D2; Rabbits; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Saphenous Vein | 1996 |
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice.
Topics: Anesthesia; Animals; Bicuculline; Central Nervous System; Dinoprost; Dinoprostone; GABA Antagonists; Gene Targeting; Hydantoins; Hyperalgesia; Immunohistochemistry; Intramolecular Oxidoreductases; Lipocalins; Mice; Mice, Knockout; Molecular Sequence Data; Pain; Prostaglandin D2; Receptors, Prostaglandin | 1999 |
Prostanoid receptors involved in the relaxation of human pulmonary vessels.
Topics: Female; Humans; Hydantoins; Iloprost; In Vitro Techniques; Male; Middle Aged; Norepinephrine; Prostaglandin D2; Prostaglandins E; Pulmonary Artery; Pulmonary Veins; Receptors, Prostaglandin; Vasodilation | 1999 |
Prostanoid receptors involved in the relaxation of human bronchial preparations.
Topics: Aged; Bronchi; Female; Humans; Hydantoins; Iloprost; In Vitro Techniques; Male; Middle Aged; Muscle Relaxation; Prostaglandin D2; Prostaglandins E; Receptors, Prostaglandin | 1999 |
Prostanoid DP receptor activation inhibits anti-IgE induced histamine release from rat peritoneal mast cells.
Topics: Animals; Antibodies; Dinoprost; Histamine Release; Hydantoins; Immunoglobulin E; Male; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin | 1999 |
Characterization of prostanoid receptors mediating inhibition of histamine release from anti-IgE-activated rat peritoneal mast cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Algorithms; Animals; Dinoprost; Histamine Release; Hydantoins; Hypersensitivity, Immediate; Male; Mast Cells; Peritoneal Cavity; Prostaglandin Antagonists; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin | 2000 |
Cyclooxygenase-2-derived prostaglandin D(2) is an early anti-inflammatory signal in experimental colitis.
Topics: Animals; Blotting, Western; Celecoxib; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hydantoins; Indomethacin; Intramolecular Oxidoreductases; Isoenzymes; Lipocalins; Male; Necrosis; Neutrophils; Peroxidase; Peroxisomes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger; Sulfonamides; Transcription Factors | 2000 |
Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection.
Topics: Animals; Cell Movement; Cyclic AMP; Eicosanoids; Epidermal Cells; Epidermis; Fluorescein-5-isothiocyanate; Hydantoins; Interleukin-10; Langerhans Cells; Mice; Mice, Knockout; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Schistosomiasis mansoni; Signal Transduction; Tumor Necrosis Factor-alpha | 2001 |
In vitro pharmacological characterization of the prostanoid receptor population in the non-pregnant porcine myometrium.
Topics: Animals; Cloprostenol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Female; Hydantoins; Iloprost; In Vitro Techniques; Muscle Contraction; Myometrium; Prostaglandin D2; Receptors, Prostaglandin; Swine | 2002 |
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dinoprostone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Guinea Pigs; Hydantoins; Hydrazines; Iloprost; In Vitro Techniques; Intestine, Small; Leukotriene Antagonists; Leukotriene D4; Male; Oxazepines; Peristalsis; Prostaglandin D2; Prostaglandins A; Receptors, Leukotriene; Receptors, Prostaglandin; Xanthenes; Xanthones; Yohimbine | 2002 |
Modulation of guinea pig intrinsic cardiac neurons by prostaglandins.
Topics: Animals; Dinoprostone; Female; Ganglia, Parasympathetic; Guinea Pigs; Heart; Hydantoins; Male; Mast Cells; Membrane Potentials; Phospholipases A; Phospholipases A2; Potassium Channel Blockers; Prostaglandin D2; Receptors, Prostaglandin; Xanthenes; Xanthones | 2003 |
Prostaglandin D2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1.
Topics: Animals; Cell Migration Inhibition; Cell Movement; Cytokines; Dendritic Cells; Down-Regulation; Epitopes, T-Lymphocyte; Hydantoins; Intubation, Intratracheal; Lung; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Transgenic; Ovalbumin; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; T-Lymphocyte Subsets; Thorax | 2003 |
Possible involvement of p38 in mechanisms underlying acceleration of proliferation by 15-deoxy-Delta(12,14)-prostaglandin J2 and the precursors in leukemia cell line THP-1.
Topics: Apoptosis; CD11 Antigens; CD11b Antigen; Cell Cycle; Cell Division; Cell Survival; Chromones; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flavonoids; Humans; Hydantoins; Imidazoles; Macrophages; Morpholines; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Prostaglandin D2; Pyridines; Time Factors; Tumor Cells, Cultured | 2004 |
Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2.
Topics: Basophils; Calcium; CD11b Antigen; Cell Movement; Cell Survival; Cells, Cultured; Chemotaxis; Histamine Release; Humans; Hydantoins; Hypersensitivity; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; Th2 Cells | 2004 |
Prostaglandin D2 mediates neuronal protection via the DP1 receptor.
Topics: Animals; Cell Survival; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoprotection; Female; Hippocampus; Hydantoins; In Situ Hybridization; Intramolecular Oxidoreductases; Lipocalins; Neurons; Neuroprotective Agents; Prostaglandin D2; Rats; Receptors, Immunologic; Receptors, Prostaglandin; Signal Transduction | 2005 |
Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells.
Topics: Base Sequence; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Cells, Cultured; Cytokines; DNA; Fatty Acids, Unsaturated; Humans; Hydantoins; Hydrazines; Inflammation; Inflammation Mediators; Interleukin-13; Interleukin-4; Interleukin-5; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Sulfonamides; Th2 Cells; Up-Regulation | 2005 |
Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans.
Topics: Adolescent; Adult; Animals; Aspirin; Female; Flushing; Humans; Hydantoins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Niacin; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Receptors, Immunologic; Receptors, Prostaglandin; Vasodilation | 2006 |
PGD(2) DP1 receptor protects brain from ischemia-reperfusion injury.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Cells, Cultured; Glutamic Acid; Hydantoins; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin | 2007 |
Divergent effects of prostaglandin receptor signaling on neuronal survival.
Topics: Animals; Animals, Newborn; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hippocampus; Hydantoins; Mice; Mice, Inbred C57BL; Neurons; Nootropic Agents; Organ Culture Techniques; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Signal Transduction; Spinal Cord; Tacrine; Time Factors | 2007 |
Pharmacological and functional characterization of novel EP and DP receptor agonists: DP1 receptor mediates penile erection in multiple species.
Topics: Aged; Alprostadil; Animals; Binding Sites; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hydantoins; In Vitro Techniques; Injections, Intravenous; Male; Middle Aged; Muscle, Smooth; Penile Erection; Phenylephrine; Phosphodiesterase Inhibitors; Prostaglandin D2; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Species Specificity; Vasodilator Agents | 2008 |
Prostaglandin D2 inhibits the production of IFN-gamma by invariant NK T cells: consequences in the control of B16 melanoma.
Topics: Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dendritic Cells; Hydantoins; Immunity, Innate; Interferon-gamma; Killer Cells, Natural; Lung Neoplasms; Melanoma, Experimental; Mice; Prostaglandin D2; Receptors, Prostaglandin; Skin Neoplasms; T-Lymphocytes | 2008 |
CRTH2 is not involved in the anti-enteropooling effect of PGD2 in the small intestine.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Female; Hydantoins; Intestinal Secretions; Intestine, Small; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin | 2008 |
15d-PGJ2 upregulates synthesis of IL-8 in endothelial cells through induction of oxidative stress.
Topics: Acetylcysteine; Cells, Cultured; Colforsin; Cyclic AMP; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Ethacrynic Acid; Ethylmaleimide; Gene Expression; Hemin; Humans; Hydantoins; Interleukin-8; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Protein Kinase Inhibitors; Reactive Oxygen Species; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Superoxide Dismutase; Transfection; Xanthones | 2008 |
GIF-0173 protects against cerebral infarction through DP1 receptor activation.
Topics: Animals; Brain Infarction; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Cerebrovascular Circulation; Dantrolene; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hydantoins; Infarction, Middle Cerebral Artery; Intracellular Fluid; Lactones; Laser-Doppler Flowmetry; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Platelet Aggregation Inhibitors; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Immunologic; Receptors, Prostaglandin; Sesquiterpenes; Severity of Illness Index; Tetrazolium Salts | 2009 |
Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease.
Topics: Adipocytes; Adipogenesis; Cells, Cultured; Coculture Techniques; Eye Diseases; Fibroblasts; Glucuronosyltransferase; Hyaluronan Synthases; Hyaluronic Acid; Hydantoins; Indoles; Isoenzymes; Mast Cells; Orbit; Prostaglandin D2; Receptors, Prostaglandin; Thyroid Diseases | 2010 |
Prostaglandin D2 regulates joint inflammation and destruction in murine collagen-induced arthritis.
Topics: Animals; Arthritis, Experimental; Bone Marrow; Chemokine CXCL1; Cytokines; Hindlimb; Hydantoins; Indoles; Interleukin-10; Interleukin-1beta; Intramolecular Oxidoreductases; Joints; Lipocalins; Mice; Mice, Inbred DBA; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Up-Regulation | 2012 |
D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells.
Topics: Calcium; Eosinophils; HEK293 Cells; Humans; Hydantoins; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Signal Transduction | 2012 |
PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis.
Topics: Anilides; Carbazoles; Cell Line; Cells, Cultured; Chemokine CCL26; Chemokines, CC; Eosinophilia; Eosinophils; Fibroblasts; Folliculitis; Humans; Hydantoins; Keratinocytes; PPAR gamma; Prostaglandin D2; Receptors, Prostaglandin; RNA, Messenger; RNA, Small Interfering; Sebaceous Glands; Skin Diseases, Vesiculobullous; Sulfonamides; Transfection | 2012 |
Prostanoid receptors involved in regulation of the beating rate of neonatal rat cardiomyocytes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Cloprostenol; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Hydantoins; Iloprost; Latanoprost; Myocytes, Cardiac; Prostaglandin D2; Prostaglandins F, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane | 2012 |
Prostaglandin D2 inhibits collagen secretion from lung fibroblasts by activating the DP receptor.
Topics: Cells, Cultured; Collagen; Cyclic AMP; Fibroblasts; Humans; Hydantoins; Lung; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Transforming Growth Factor beta | 2013 |
Prostaglandin D2 receptor D-type prostanoid receptor 2 mediates eosinophil trafficking into the esophagus.
Topics: Animals; Carbazoles; Cell Movement; Eosinophil Major Basic Protein; Eosinophilic Esophagitis; Eosinophils; Epithelium; Esophagus; Guinea Pigs; Hydantoins; Male; Mast Cells; Ovalbumin; Prostaglandin Antagonists; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Sulfonamides | 2014 |
A novel indole compound, AWT-489, inhibits prostaglandin D2-induced CD55 expression by acting on DP prostanoid receptors as an antagonist in LS174T human colon cancer cells.
Topics: Carcinogenesis; CD55 Antigens; Cell Line, Tumor; Colonic Neoplasms; Cyclic AMP; Dinoprostone; Drug Design; Gene Expression Regulation, Neoplastic; Humans; Hydantoins; Indoles; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger | 2014 |