bw 245c has been researched along with hydantoins in 86 studies
| Studies (bw 245c) | Trials (bw 245c) | Recent Studies (post-2010) (bw 245c) | Studies (hydantoins) | Trials (hydantoins) | Recent Studies (post-2010) (hydantoins) |
|---|---|---|---|---|---|
| 96 | 3 | 10 | 3,404 | 80 | 435 |
| Protein | Taxonomy | bw 245c (IC50) | hydantoins (IC50) |
|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.062 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (24.42) | 18.7374 |
| 1990's | 21 (24.42) | 18.2507 |
| 2000's | 32 (37.21) | 29.6817 |
| 2010's | 12 (13.95) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baxter, GS; Clayton, JK; Marshall, K; Sangha, R; Senior, J | 1 |
| Barraclough, P; Harris, CJ; Jackson, WP | 1 |
| Fairbairn, CE; Goodrum, DD; Krauss, AH; Ralston, TL; Williams, LS; Woodward, DF | 1 |
| al-Lamee, KG; Bamford, CH; Middleton, IP | 2 |
| Azuma, I; Goh, Y; Hayaishi, O; Nakajima, M | 1 |
| Church, MK; Featherstone, RL; Holgate, ST; Robinson, C | 1 |
| Hawley, SB; Nieves, AL; Protzman, CE; Ralston, TR; Spada, CS; Williams, LS; Woodward, DF | 1 |
| Keery, RJ; Lumley, P | 1 |
| Collins, BA; Kelly, MG; Robertson, AD; Trist, DG; Wood, J | 1 |
| Hamid-Bloomfield, S; Whittle, BJ | 1 |
| Hamid, S; Lidbury, P; Rosam, AC; Whittle, BJ | 1 |
| Bolofo, ML; Giles, H; Kelly, MG; Leff, P; Robertson, AD | 1 |
| Hamid, S; Whittle, BJ | 1 |
| Narumiya, S; Toda, N | 1 |
| Hughes, RD; Noda, Y; Williams, R | 1 |
| Ivanyi, J; Kay, JE; Kingston, AE | 1 |
| Al-Sinawi, LA; Burke, C; Hassan, S; Hedges, A; Mekki, QA; Moody, SG; O'Grady, J | 1 |
| Andersen, NH; Hanson, SR; Harker, LA; Tynan, SS; Wills, MT | 1 |
| Kakkar, VV; Zahavi, J; Zahavi, M | 1 |
| De Sarro, A; De Sarro, GB; Ientile, R; Nistico, G; Rotiroti, D | 1 |
| Casals-Stenzel, J; Schillinger, E; Town, MH | 1 |
| Moncada, S; Mullane, K; Vane, JR; Whittle, BJ | 1 |
| Lewis, PJ; Orchard, MA; Ritter, JM; Shepherd, GL | 1 |
| Coceani, F; Hamilton, F; Olley, PM; Sideris, E; Yokochi, K | 1 |
| Joshi, M; O'Grady, J; Pickles, H; Shah, A; Webster, A | 1 |
| Bennett, A; Jackson, A; Sanger, GJ | 1 |
| Naccari, F; Nisticò, G; Rotiroti, D | 1 |
| Betti, PA; Prior, ET; Rangachari, PK; Roberts, LJ | 1 |
| Crankshaw, D; Fernandes, B | 1 |
| Giles, H; Kageyama, M; Matsugi, T; Nishimura, K; Shirasawa, E | 1 |
| Barraclough, P; Brockwell, M; Caldwell, AG; Demaine, DA; Harris, CJ; King, WR; Stepney, RJ; Wharton, CJ; Whittle, BJ | 1 |
| Lawrence, RA; Woodward, DF | 1 |
| Vardey, CJ; Wheeldon, A | 1 |
| Barraclough, P; Bolofo, ML; Giles, H; Gillam, J; Harris, CJ; Kelly, MG; Leff, P; McNeill, A; Robertson, AD; Stepney, RJ; Whittle, BJ | 1 |
| Blackham, A; Jackson, DM; Leff, P; Liu, YJ | 1 |
| Leff, P; Lydford, SJ; McKechnie, KC | 1 |
| Crider, JY; Griffin, BW; Sharif, NA; Williams, GW | 1 |
| Eguchi, N; Hayaishi, O; Ito, S; Kanaoka, Y; Minami, T; Nagata, A; Shirafuji, N; Tanaka, T; Urade, Y; Yoshida, N | 1 |
| Brink, C; de Montpreville, V; Gascard, JP; Labat, C; Norel, X; Walch, L | 1 |
| Brink, C; Dulmet, E; Gascard, JP; Labat, C; Norel, X; Walch, L | 1 |
| Chan, CL; Lau, HY | 1 |
| Chan, CL; Jones, RL; Lau, HY | 1 |
| Ajuebor, MN; Singh, A; Wallace, JL | 1 |
| Al-Lamee, KG; Middleton, IP; Paprotny, J | 1 |
| Angeli, V; Capron, A; Capron, M; Faveeuw, C; Fontaine, J; Roye, O; Teissier, E; Trottein, F; Wolowczuk, I | 1 |
| Foley, JF; Kelley, LP; Kinsella, BT | 1 |
| Hu, DN; McCormick, SA; Woodward, DF | 1 |
| Cao, J; Kitazawa, T; Shayibuzhati, M; Tajima, T; Taneike, T | 1 |
| Nieves, AL; Spada, CS; Woodward, DF | 1 |
| Heinemann, A; Holzer, P; Peskar, BA; Shahbazian, A | 1 |
| Albadawi, H; Goldstein, I; Kim, NN; Min, KS; Moreland, RB; Nehra, A; Traish, AM; Watkins, MT | 1 |
| DeMasi, GM; Hardwick, JC; Jelson, GS; Sager, KL | 1 |
| Jones, RL; Kan, KK; Ngan, MP; Rudd, JA | 2 |
| de Heer, HJ; Hammad, H; Hoogsteden, HC; Lambrecht, BN; Soullie, T; Trottein, F | 1 |
| Sharif, NA; Xu, SX | 1 |
| Azuma, Y; Daito, M; Date, M; Ohura, K; Watanabe, K | 1 |
| Bacon, KB; Hirai, K; Iikura, M; Ishii, A; Matsushima, K; Nagase, H; Shichijo, M; Yamaguchi, M; Yamamoto, K; Yoshimura-Uchiyama, C | 1 |
| Kinsella, BT; O'Meara, SJ | 1 |
| Andreasson, K; Hand, T; Liang, X; Wu, L | 1 |
| Gazi, L; Gyles, SL; Hunter, MG; Pettipher, R; Townsend, E; Wettey, FR; Xue, L | 1 |
| Cox, BF; Koch, KA; Moreland, R; Reinhart, GA; Wessale, JL | 1 |
| Cheng, K; Gottesdiener, K; Lai, E; Metters, K; O'Neill, G; Sturino, C; Wang, Z; Waters, MG; Wright, SD; Wu, KK; Wu, TJ | 1 |
| de Brum-Fernandes, AJ; Gallant, MA; Miousse, MC; Parent, JL; Samadfam, R | 1 |
| de Brum-Fernandes, AJ; Doré, S; Maruyama, T; Narumiya, S; Saleem, S; Zhuang, H | 1 |
| Andreasson, K; Liang, X; Wang, Q; Wu, L | 1 |
| Araldi, GL; Brugger, N; Kim, NN; Palmer, SS; Traish, AM | 1 |
| Capron, M; Faveeuw, C; Fontaine, J; Gosset, P; Mallevaey, T; Maruyama, T; Matsuoka, T; Narumiya, S; Paget, C; Torres, D; Trottein, F | 1 |
| Heinemann, A; Peskar, BA; Prenn, C; Schuligoi, R | 1 |
| Cisowski, J; Dulak, J; Jozkowicz, A; Kotlinowski, J; Mleczko, K; Taha, H; Was, H; Weigel, G | 1 |
| Aritake, K; Hori, M; Lin, MI; Matsumoto, S; Murata, T; Narumiya, S; Ozaki, H; Sessa, WC; Urade, Y | 1 |
| Furuta, K; Hokamura, K; Ibaraki, K; Maeda, M; Suzuki, M; Thura, M; Umemura, K; Yamamoto, S | 1 |
| Bing, N; Cox, RF; Gauthier, J; Jensen, D; Johnson, EN; Kostura, M; Murray, DL; Sorensen, SD; Vanderwall, D; Wang, P; Xu, Z | 1 |
| Baglole, CJ; Feldon, SE; Guo, N; O'Loughlin, CW; Phipps, RP | 1 |
| Huaux, F; Lison, D; Uwambayinema, F; van den Brule, S; Wallemme, L | 1 |
| Alcaraz, MJ; Ferrándiz, ML; Ibáñez, L; Maicas, N; Úbeda, A | 1 |
| Bell, K; Heinemann, A; Kostenis, E; Platzer, W; Schröder, R; Sedej, M; Vukoja, A; Waldhoer, M | 1 |
| Doi, H; Egawa, G; Hirabayashi, T; Kabashima, K; Miyachi, Y; Murakami, M; Nakahigashi, K; Otsuka, A; Tanizaki, H; Urade, Y; Zouboulis, CC | 1 |
| Devillier, P; Grassin-Delyle, S; Mechiche, H; Nazeyrollas, P; Robinet, A | 1 |
| Ayabe, S; Hori, M; Kida, T; Murata, T; Ozaki, H | 1 |
| Wu, X; Yu, S; Zhang, S | 1 |
| Arai, T; Awata, A; Fujino, H; Murayama, T; Okura, I; Oyama, S; Regan, JW; Yamazaki, R | 1 |
| Ahmad, AS | 1 |
| Afif, H; Benderdour, M; Fahmi, H; Habouri, L; Kapoor, M; Lussier, B; Martel-Pelletier, J; Narumiya, S; Nebbaki, SS; Ouhaddi, Y; Pelletier, JP | 1 |
| Hirai, R; Masuko, S; Murata, T; Nagata, N; Nakamura, T; Tachibana, Y | 1 |
1 review(s) available for bw 245c and hydantoins
| Article | Year |
|---|---|
Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin E1 and D2 on platelets.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Membrane; Epoprostenol; Humans; Hydantoins; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Prostaglandins, Synthetic; Radioligand Assay; Receptors, Epoprostenol; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Species Specificity; Structure-Activity Relationship | 1985 |
3 trial(s) available for bw 245c and hydantoins
| Article | Year |
|---|---|
Effects of prostaglandin D2 and its analogue, BW245C, on intraocular pressure in humans.
Topics: Administration, Topical; Adult; Conjunctiva; Double-Blind Method; Female; Humans; Hydantoins; Hyperemia; Intraocular Pressure; Male; Prostaglandin D2; Pruritus; Tonometry, Ocular | 1991 |
Effect of a hydantoin prostaglandin analogue, BW245C, during oral dosing in man.
Topics: Adenosine Diphosphate; Administration, Oral; Adult; Blood Pressure; Double-Blind Method; Drug Evaluation; Electrocardiography; Flushing; Headache; Heart Rate; Humans; Hydantoins; Male; Platelet Aggregation | 1985 |
Effects of single oral dose administration of a hydantoin prostaglandin analogue BW 245C in man.
Topics: Administration, Oral; Adult; Blood Pressure; Female; Flushing; Heart Rate; Humans; Hydantoins; Male; Pilot Projects; Platelet Aggregation | 1984 |
82 other study(ies) available for bw 245c and hydantoins
| Article | Year |
|---|---|
In vitro characterization of prostanoid FP-, DP-, IP- and TP-receptors on the non-pregnant human myometrium.
Topics: Female; Humans; Hydantoins; In Vitro Techniques; Myometrium; Prostaglandin Antagonists; Prostaglandins; Receptors, Epoprostenol; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Thromboxane; Uterine Contraction | 1992 |
Imidazolidin-2-one prostaglandin analogues.
Topics: Cyclohexanes; Humans; Hydantoins; Imidazoles; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins, Synthetic; Structure-Activity Relationship | 1991 |
Ca2+ transients evoked by prostanoids in Swiss 3T3 cells suggest an FP-receptor mediated response.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Dinoprost; Dose-Response Relationship, Drug; Fibroblasts; Hydantoins; Mice; Phenylacetates; Platelet-Derived Growth Factor; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins F, Synthetic; Receptors, Prostaglandin; Sulfonamides | 1991 |
Influence of molecular structure on the synergistic action of theophylline or dipyridamole derivatives in the prostaglandin-type inhibition of platelet aggregation.
Topics: Animals; Dipyridamole; Drug Synergism; Hydantoins; Molecular Structure; Molecular Weight; Platelet Aggregation Inhibitors; Polymers; Sheep; Structure-Activity Relationship; Theophylline | 1991 |
Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9 alpha,11 beta-PGF2 and PGF2 alpha.
Topics: Animals; Biphenyl Compounds; Bronchi; Dinoprost; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Humans; Hydantoins; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin D2; Prostaglandins, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxanes; Trachea | 1990 |
Studies on the ocular pharmacology of prostaglandin D2.
Topics: Animals; Aqueous Humor; Capillary Permeability; Chemotaxis, Leukocyte; Conjunctiva; Dinoprost; Eosinophils; Evans Blue; Eye; Female; Guinea Pigs; Hydantoins; Inflammation; Intraocular Pressure; Male; Prostaglandin D2; Rabbits | 1990 |
Polymeric inhibitors of platelet aggregation. Synergistic effects and proposals for a new mechanism.
Topics: Adenosine Diphosphate; Animals; Dextrans; Drug Synergism; Hydantoins; Kinetics; Platelet Aggregation; Polyethylene Glycols; Povidone; Sheep; Theophylline | 1986 |
AH6809, a prostaglandin DP-receptor blocking drug on human platelets.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Dinoprost; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Receptors, Immunologic; Receptors, Prostaglandin; Xanthenes; Xanthones | 1988 |
The antagonism by BW A868C of PGD2 and BW245C activation of human platelet adenylate cyclase.
Topics: Adenylyl Cyclases; Blood Platelets; Enzyme Activation; Epoprostenol; Humans; Hydantoins; Iloprost; In Vitro Techniques; Platelet Aggregation; Prostaglandin D2; Receptors, Prostaglandin | 1989 |
Antagonism of PGD2 vasodepressor responses in the rat in vivo by the novel, selective antagonist, BW A868C.
Topics: Animals; Blood Pressure; Epoprostenol; Hydantoins; Infusions, Intravenous; Male; Prostaglandin D2; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Sulfonamides | 1989 |
The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; Blood Vessels; Guinea Pigs; Humans; Hydantoins; In Vitro Techniques; Jugular Veins; Male; Muscle Contraction; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Prostaglandin; Sulfonamides; Trachea | 1989 |
Interaction of prostaglandin D2 with prostacyclin, carbacyclin and the hydantoin prostaglandin, BW245C, in guinea-pig platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Bucladesine; Colforsin; Diterpenes; Drug Interactions; Epoprostenol; Guinea Pigs; Hydantoins; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin D2; Prostaglandins D | 1985 |
Different responsiveness of prostaglandin D2-sensitive systems to prostaglandin D2 and its analogues.
Topics: Animals; Cerebral Arteries; Cyclic AMP; Dogs; Guinea Pigs; Humans; Hydantoins; Mast Cells; Muscle Contraction; Muscle Relaxation; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Rabbits; Rats; Rats, Inbred Strains; Stomach; Trachea | 1985 |
Effect of prostacyclin (PGI2) and a prostaglandin analogue BW 245C on galactosamine-induced hepatic necrosis.
Topics: Acetylglucosaminidase; Animals; Aspartate Aminotransferases; Cathepsin D; Epoprostenol; Galactosamine; Hydantoins; Liver; Male; Necrosis; Nucleotides, Cyclic; Rats; Rats, Inbred Strains | 1986 |
The effects of prostaglandin E and I analogues on lymphocyte stimulation.
Topics: Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Leucine; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Prostaglandins E; Prostaglandins E, Synthetic; Protein Biosynthesis | 1985 |
On the multiplicity of platelet prostaglandin receptors. II. The use of N-0164 for distinguishing the loci of action for PGI2, PGD2, PGE2 and hydantoin analogs.
Topics: Blood Platelets; Dinoprostone; Epoprostenol; Humans; Hydantoins; Organophosphonates; Organophosphorus Compounds; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Receptors, Cell Surface; Receptors, Prostaglandin; Structure-Activity Relationship | 1984 |
Effect of adenyl-cyclase activators, phosphodiesterase inhibitors and pyridoxal-5-phosphate on platelet aggregation and adenosine-3'-5'-cyclic monophosphate accumulation.
Topics: Adenylyl Cyclases; Adult; Alprostadil; Blood Platelets; Cyclic AMP; Dipyridamole; Female; Humans; Hydantoins; Male; Middle Aged; Papaverine; Phosphodiesterase Inhibitors; Platelet Aggregation; Prostaglandins E; Pyridoxal Phosphate; Theophylline | 1984 |
Stimulation of rat caudate nucleus adenylate cyclase activity by BW 245 C, a prostaglandin analogue with prostacyclin-like activity.
Topics: Adenylyl Cyclases; Animals; Caudate Nucleus; Chlorpromazine; Hydantoins; Male; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Sulpiride | 1983 |
Pharmacological and cardiovascular properties of a hydantoin derivative, BW 245 C, with high affinity and selectivity for PGD2 receptors.
Topics: Animals; Blood Platelets; Blood Pressure; Cattle; Female; Heart Rate; Hemodynamics; Humans; Hydantoins; Hypertension; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Rats; Receptors, Cell Surface; Receptors, Prostaglandin; Subcellular Fractions; Thromboxanes; Uterus | 1983 |
Platelet and cardiovascular activity of the hydantoin BW245C, a potent prostaglandin analogue.
Topics: Animals; Arteries; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Female; Gastric Juice; Gastric Mucosa; Horses; Humans; Hydantoins; Male; Platelet Aggregation; Prostaglandin D2; Prostaglandins; Prostaglandins D; Rabbits; Rats; Rats, Inbred Strains; Sheep; Species Specificity; Structure-Activity Relationship | 1983 |
Cardiovascular and platelet effects in man of BW 245C, a stable mimic of epoprostenol (PGI2).
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Blood Pressure; Electrocardiography; Epoprostenol; Heart Rate; Hemodynamics; Humans; Hydantoins; Male; Prostaglandins; Time Factors | 1983 |
Action of PGI2 analogs on the pulmonary and systemic circulations in the conscious newborn lamb.
Topics: Animals; Animals, Newborn; Blood Pressure; Cardiac Output; Epoprostenol; Hydantoins; Pulmonary Circulation; Regional Blood Flow; Sheep; Vascular Resistance; Vasodilation | 1984 |
A prostaglandin analogue which potently relaxes human uterus but not gut muscle.
Topics: Digestive System; Epoprostenol; Female; Humans; Hydantoins; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Myometrium; Uterus | 1982 |
Behavioural, ECoG spectrum power and body temperature effects of BW 245C, a prostaglandin analogue after intraventricular microinjection in chicks.
Topics: Animals; Behavior, Animal; Body Temperature; Cerebral Cortex; Chickens; Electric Conductivity; Hydantoins; Injections, Intraventricular; Microinjections; Motor Activity; Vocalization, Animal | 1981 |
Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: an argument for a different DP receptor?
Topics: Animals; Colon; Dogs; Electrophysiology; Female; Hydantoins; In Vitro Techniques; Intestinal Mucosa; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin | 1995 |
Functional characterization of the prostanoid DP receptor in human myometrium.
Topics: Adult; Dinoprost; Dose-Response Relationship, Drug; Female; Humans; Hydantoins; Hysterectomy; Middle Aged; Muscle Contraction; Muscle, Smooth; Myometrium; Prostaglandin D2; Prostanoic Acids; Receptors, Prostaglandin | 1995 |
Selective prostaglandin D2 receptor stimulation elicits ocular hypotensive effects in rabbits and cats.
Topics: Animals; Butyrates; Cats; Hydantoins; Imidazoles; Intraocular Pressure; Male; Rabbits; Receptors, Immunologic; Receptors, Prostaglandin | 1995 |
Synthesis and inhibitory activity on platelet aggregation of 13'-aza and other omega-chain modified BW245C analogues.
Topics: Animals; Dogs; Hemodynamics; Humans; Hydantoins; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Wistar; Structure-Activity Relationship; Vasodilator Agents | 1994 |
Identification of a single (FP) receptor associated with prostanoid-induced Ca2+ signals in Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Binding, Competitive; Calcium; Dinoprostone; Hydantoins; Mice; Prostaglandin D2; Prostaglandins F; Prostaglandins F, Synthetic; Receptors, Prostaglandin; Second Messenger Systems | 1994 |
Characterization of the inhibitory prostanoid receptors on human neutrophils.
Topics: Humans; Hydantoins; In Vitro Techniques; Leukotriene B4; Misoprostol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Prostaglandin Antagonists; Prostaglandins; Prostanoic Acids; Receptors, Prostaglandin; Superoxides; Xanthenes; Xanthones; Zymosan | 1993 |
Synthesis of Hexahydrocyclopentimidazol-2-(1H)-one derivatives displaying selective DP-receptor agonist properties.
Topics: Animals; Blood Pressure; Butyrates; Drug Design; Humans; Hydantoins; Imidazoles; Jugular Veins; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Receptors, Prostaglandin; Structure-Activity Relationship | 1996 |
Partial agonist effects of BW A868C, a selective DP receptor antagonist, on Cl- secretion in dog tracheal epithelium.
Topics: Animals; Chlorides; Dogs; Drug Interactions; Epithelium; Female; Hydantoins; In Vitro Techniques; Male; Models, Biological; Prostaglandins D; Receptors, Prostaglandin; Trachea | 1996 |
Interaction of BW A868C, a prostanoid DP-receptor antagonist, with two receptor subtypes in the rabbit isolated saphenous vein.
Topics: Animals; Anti-Arrhythmia Agents; Biphenyl Compounds; Dinoprostone; Dose-Response Relationship, Drug; Hydantoins; Male; Potassium Chloride; Prostaglandin D2; Rabbits; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Saphenous Vein | 1996 |
FP prostaglandin receptors mediating inositol phosphates generation and calcium mobilization in Swiss 3T3 cells: a pharmacological study.
Topics: 3T3 Cells; Animals; Calcium; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Hydantoins; Inositol Phosphates; Mice; Prostaglandin Antagonists; Protein Binding; Receptors, Prostaglandin; Xanthenes; Xanthones | 1997 |
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice.
Topics: Anesthesia; Animals; Bicuculline; Central Nervous System; Dinoprost; Dinoprostone; GABA Antagonists; Gene Targeting; Hydantoins; Hyperalgesia; Immunohistochemistry; Intramolecular Oxidoreductases; Lipocalins; Mice; Mice, Knockout; Molecular Sequence Data; Pain; Prostaglandin D2; Receptors, Prostaglandin | 1999 |
Prostanoid receptors involved in the relaxation of human pulmonary vessels.
Topics: Female; Humans; Hydantoins; Iloprost; In Vitro Techniques; Male; Middle Aged; Norepinephrine; Prostaglandin D2; Prostaglandins E; Pulmonary Artery; Pulmonary Veins; Receptors, Prostaglandin; Vasodilation | 1999 |
Prostanoid receptors involved in the relaxation of human bronchial preparations.
Topics: Aged; Bronchi; Female; Humans; Hydantoins; Iloprost; In Vitro Techniques; Male; Middle Aged; Muscle Relaxation; Prostaglandin D2; Prostaglandins E; Receptors, Prostaglandin | 1999 |
Prostanoid DP receptor activation inhibits anti-IgE induced histamine release from rat peritoneal mast cells.
Topics: Animals; Antibodies; Dinoprost; Histamine Release; Hydantoins; Immunoglobulin E; Male; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin | 1999 |
Characterization of prostanoid receptors mediating inhibition of histamine release from anti-IgE-activated rat peritoneal mast cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Algorithms; Animals; Dinoprost; Histamine Release; Hydantoins; Hypersensitivity, Immediate; Male; Mast Cells; Peritoneal Cavity; Prostaglandin Antagonists; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin | 2000 |
Cyclooxygenase-2-derived prostaglandin D(2) is an early anti-inflammatory signal in experimental colitis.
Topics: Animals; Blotting, Western; Celecoxib; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hydantoins; Indomethacin; Intramolecular Oxidoreductases; Isoenzymes; Lipocalins; Male; Necrosis; Neutrophils; Peroxidase; Peroxisomes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger; Sulfonamides; Transcription Factors | 2000 |
Professor Bamford's research in the field of biomaterials.
Topics: Amino Acids; Amino Sugars; Biochemistry; Biocompatible Materials; Dipyridamole; History, 20th Century; Hydantoins; Phosphodiesterase Inhibitors; Polyethylene Glycols; Polymers; Theophylline | 2000 |
Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection.
Topics: Animals; Cell Movement; Cyclic AMP; Eicosanoids; Epidermal Cells; Epidermis; Fluorescein-5-isothiocyanate; Hydantoins; Interleukin-10; Langerhans Cells; Mice; Mice, Knockout; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Schistosomiasis mansoni; Signal Transduction; Tumor Necrosis Factor-alpha | 2001 |
Prostaglandin D(2) receptor-mediated desensitization of the alpha isoform of the human thromboxane A(2) receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Cells, Cultured; Humans; Hydantoins; Inositol 1,4,5-Trisphosphate; Phosphorylation; Protein Isoforms; Receptor Cross-Talk; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Thromboxane; Signal Transduction; Vasoconstrictor Agents | 2001 |
A functional study on prostanoid receptors involved in cultured human iridal melanocyte stimulation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Cell Count; Cells, Cultured; Cyclic AMP; Dinoprostone; Epoprostenol; Fibroblast Growth Factor 2; Humans; Hydantoins; Iris; Melanins; Melanocytes; Prostaglandin Antagonists; Prostanoic Acids; Receptors, Prostaglandin | 2001 |
In vitro pharmacological characterization of the prostanoid receptor population in the non-pregnant porcine myometrium.
Topics: Animals; Cloprostenol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Female; Hydantoins; Iloprost; In Vitro Techniques; Muscle Contraction; Myometrium; Prostaglandin D2; Receptors, Prostaglandin; Swine | 2002 |
Vascular activities of prostaglandins and selective prostanoid receptor agonists in human retinal microvessels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cricetinae; Dose-Response Relationship, Drug; Humans; Hydantoins; Microcirculation; Prostaglandins; Prostaglandins F, Synthetic; Receptors, Prostaglandin; Retinal Vessels | 2002 |
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dinoprostone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Guinea Pigs; Hydantoins; Hydrazines; Iloprost; In Vitro Techniques; Intestine, Small; Leukotriene Antagonists; Leukotriene D4; Male; Oxazepines; Peristalsis; Prostaglandin D2; Prostaglandins A; Receptors, Leukotriene; Receptors, Prostaglandin; Xanthenes; Xanthones; Yohimbine | 2002 |
Expression of functional prostaglandin D (DP) receptors in human corpus cavernosum smooth muscle.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Humans; Hydantoins; Hydrazines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Penis; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger; Vasoconstriction; Vasodilation | 2002 |
Modulation of guinea pig intrinsic cardiac neurons by prostaglandins.
Topics: Animals; Dinoprostone; Female; Ganglia, Parasympathetic; Guinea Pigs; Heart; Hydantoins; Male; Mast Cells; Membrane Potentials; Phospholipases A; Phospholipases A2; Potassium Channel Blockers; Prostaglandin D2; Receptors, Prostaglandin; Xanthenes; Xanthones | 2003 |
Action of prostanoids on the emetic reflex of Suncus murinus (the house musk shrew).
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Biphenyl Compounds; Copper Sulfate; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Hydantoins; Injections, Intraperitoneal; Injections, Subcutaneous; Intubation, Gastrointestinal; Male; Nausea; Nicotine; Prostaglandins; Prostaglandins F, Synthetic; Reaction Time; Receptors, Thromboxane; Shrews; Time Factors; Vomiting | 2003 |
Prostaglandin D2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1.
Topics: Animals; Cell Migration Inhibition; Cell Movement; Cytokines; Dendritic Cells; Down-Regulation; Epitopes, T-Lymphocyte; Hydantoins; Intubation, Intratracheal; Lung; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Transgenic; Ovalbumin; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; T-Lymphocyte Subsets; Thorax | 2003 |
Pharmacological characterization and identification of EP3 prostanoid receptor binding sites in hamster uterus homogenates.
Topics: Animals; Binding Sites; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cloprostenol; Cricetinae; Dinoprost; Dinoprostone; Enprostil; Epoprostenol; Fatty Acids, Unsaturated; Female; Hydantoins; Hydrazines; Iloprost; Latanoprost; Misoprostol; Prostaglandins; Prostaglandins E, Synthetic; Prostaglandins F, Synthetic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Tritium; Uterus | 2004 |
Possible involvement of p38 in mechanisms underlying acceleration of proliferation by 15-deoxy-Delta(12,14)-prostaglandin J2 and the precursors in leukemia cell line THP-1.
Topics: Apoptosis; CD11 Antigens; CD11b Antigen; Cell Cycle; Cell Division; Cell Survival; Chromones; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flavonoids; Humans; Hydantoins; Imidazoles; Macrophages; Morpholines; p38 Mitogen-Activated Protein Kinases; Phenanthrenes; Prostaglandin D2; Pyridines; Time Factors; Tumor Cells, Cultured | 2004 |
Excitatory action of prostanoids on the ferret isolated vagus nerve preparation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Biguanides; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Electrophysiology; Epoprostenol; Ferrets; Hydantoins; Iloprost; In Vitro Techniques; Male; Prostaglandins; Prostaglandins F, Synthetic; Serotonin; Vagus Nerve | 2004 |
Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2.
Topics: Basophils; Calcium; CD11b Antigen; Cell Movement; Cell Survival; Cells, Cultured; Chemotaxis; Histamine Release; Humans; Hydantoins; Hypersensitivity; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; Th2 Cells | 2004 |
Effect of the statin atorvastatin on intracellular signalling by the prostacyclin receptor in vitro and in vivo.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Animals; Atorvastatin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Line; Cell Line, Tumor; Cholesterol; Clinical Trials as Topic; Cyclic AMP; Drug Evaluation, Preclinical; Fatty Acids, Unsaturated; Female; Heptanoic Acids; Humans; Hydantoins; Hydrazines; Iloprost; Ireland; Lipids; Male; Mice; Middle Aged; Propanolamines; Protein Prenylation; Pyrroles; Radioligand Assay; Receptor Cross-Talk; Receptors, Epoprostenol; Receptors, Immunologic; Receptors, Prostaglandin; Signal Transduction; Tritium | 2004 |
Prostaglandin D2 mediates neuronal protection via the DP1 receptor.
Topics: Animals; Cell Survival; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoprotection; Female; Hippocampus; Hydantoins; In Situ Hybridization; Intramolecular Oxidoreductases; Lipocalins; Neurons; Neuroprotective Agents; Prostaglandin D2; Rats; Receptors, Immunologic; Receptors, Prostaglandin; Signal Transduction | 2005 |
Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells.
Topics: Base Sequence; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Cells, Cultured; Cytokines; DNA; Fatty Acids, Unsaturated; Humans; Hydantoins; Hydrazines; Inflammation; Inflammation Mediators; Interleukin-13; Interleukin-4; Interleukin-5; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Sulfonamides; Th2 Cells; Up-Regulation | 2005 |
Effects of BW245C, a prostaglandin dp receptor agonist, on systemic and regional haemodynamics in the anaesthetized rat.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hemodynamics; Hydantoins; Infusions, Intravenous; Injections, Intraperitoneal; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Regional Blood Flow; Skin; Thiopental; Vascular Resistance; Vasodilation; Vasodilator Agents | 2005 |
Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans.
Topics: Adolescent; Adult; Animals; Aspirin; Female; Flushing; Humans; Hydantoins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Niacin; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Receptors, Immunologic; Receptors, Prostaglandin; Vasodilation | 2006 |
Implication of prostaglandin receptors in the accumulation of osteoprotegerin in human osteoblast cultures.
Topics: Cell Line, Transformed; Cell Line, Tumor; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Gene Expression; Glycoproteins; Humans; Hydantoins; Osteoblasts; Osteoprotegerin; Prostaglandin-Endoperoxide Synthases; Prostaglandins F, Synthetic; Receptors, Cytoplasmic and Nuclear; Receptors, Prostaglandin; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
PGD(2) DP1 receptor protects brain from ischemia-reperfusion injury.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Cells, Cultured; Glutamic Acid; Hydantoins; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin | 2007 |
Divergent effects of prostaglandin receptor signaling on neuronal survival.
Topics: Animals; Animals, Newborn; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hippocampus; Hydantoins; Mice; Mice, Inbred C57BL; Neurons; Nootropic Agents; Organ Culture Techniques; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Signal Transduction; Spinal Cord; Tacrine; Time Factors | 2007 |
Pharmacological and functional characterization of novel EP and DP receptor agonists: DP1 receptor mediates penile erection in multiple species.
Topics: Aged; Alprostadil; Animals; Binding Sites; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hydantoins; In Vitro Techniques; Injections, Intravenous; Male; Middle Aged; Muscle, Smooth; Penile Erection; Phenylephrine; Phosphodiesterase Inhibitors; Prostaglandin D2; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Species Specificity; Vasodilator Agents | 2008 |
Prostaglandin D2 inhibits the production of IFN-gamma by invariant NK T cells: consequences in the control of B16 melanoma.
Topics: Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dendritic Cells; Hydantoins; Immunity, Innate; Interferon-gamma; Killer Cells, Natural; Lung Neoplasms; Melanoma, Experimental; Mice; Prostaglandin D2; Receptors, Prostaglandin; Skin Neoplasms; T-Lymphocytes | 2008 |
CRTH2 is not involved in the anti-enteropooling effect of PGD2 in the small intestine.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Female; Hydantoins; Intestinal Secretions; Intestine, Small; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin | 2008 |
15d-PGJ2 upregulates synthesis of IL-8 in endothelial cells through induction of oxidative stress.
Topics: Acetylcysteine; Cells, Cultured; Colforsin; Cyclic AMP; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Ethacrynic Acid; Ethylmaleimide; Gene Expression; Hemin; Humans; Hydantoins; Interleukin-8; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Protein Kinase Inhibitors; Reactive Oxygen Species; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Superoxide Dismutase; Transfection; Xanthones | 2008 |
Role of prostaglandin D2 receptor DP as a suppressor of tumor hyperpermeability and angiogenesis in vivo.
Topics: Animals; Capillary Permeability; Cell Movement; Cell Proliferation; Corneal Neovascularization; Cyclic AMP; Endothelium, Vascular; Hydantoins; Interleukin-1beta; Mice; Mice, Mutant Strains; Neoplasms; Neovascularization, Pathologic; Receptors, Immunologic; Receptors, Prostaglandin; Vascular Endothelial Growth Factor A | 2008 |
GIF-0173 protects against cerebral infarction through DP1 receptor activation.
Topics: Animals; Brain Infarction; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Cerebrovascular Circulation; Dantrolene; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hydantoins; Infarction, Middle Cerebral Artery; Intracellular Fluid; Lactones; Laser-Doppler Flowmetry; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Platelet Aggregation Inhibitors; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Immunologic; Receptors, Prostaglandin; Sesquiterpenes; Severity of Illness Index; Tetrazolium Salts | 2009 |
Functional antagonism of IL-1alpha induced gene expression profiles define the cAMP/PKA pathway as a unique regulator of IL-1alpha signaling networks.
Topics: Alprostadil; Anti-Ulcer Agents; Calcium; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fibroblasts; Gene Expression Profiling; Humans; Hydantoins; I-kappa B Kinase; Iloprost; Interleukin-1alpha; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Kinase Kinases; Misoprostol; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Platelet Aggregation Inhibitors; Prostaglandins E, Synthetic; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Signal Transduction | 2009 |
Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease.
Topics: Adipocytes; Adipogenesis; Cells, Cultured; Coculture Techniques; Eye Diseases; Fibroblasts; Glucuronosyltransferase; Hyaluronan Synthases; Hyaluronic Acid; Hydantoins; Indoles; Isoenzymes; Mast Cells; Orbit; Prostaglandin D2; Receptors, Prostaglandin; Thyroid Diseases | 2010 |
The D prostanoid receptor agonist BW245C [(4S)-(3-[(3R,S)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxo)-4-imidazolidineheptanoic acid] inhibits fibroblast proliferation and bleomycin-induced lung fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Proliferation; Cells, Cultured; Collagen; Female; Fibroblasts; Humans; Hydantoins; Interleukin-13; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Receptors, Prostaglandin; Transforming Growth Factor beta | 2010 |
Prostaglandin D2 regulates joint inflammation and destruction in murine collagen-induced arthritis.
Topics: Animals; Arthritis, Experimental; Bone Marrow; Chemokine CXCL1; Cytokines; Hindlimb; Hydantoins; Indoles; Interleukin-10; Interleukin-1beta; Intramolecular Oxidoreductases; Joints; Lipocalins; Mice; Mice, Inbred DBA; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Up-Regulation | 2012 |
D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells.
Topics: Calcium; Eosinophils; HEK293 Cells; Humans; Hydantoins; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Signal Transduction | 2012 |
PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis.
Topics: Anilides; Carbazoles; Cell Line; Cells, Cultured; Chemokine CCL26; Chemokines, CC; Eosinophilia; Eosinophils; Fibroblasts; Folliculitis; Humans; Hydantoins; Keratinocytes; PPAR gamma; Prostaglandin D2; Receptors, Prostaglandin; RNA, Messenger; RNA, Small Interfering; Sebaceous Glands; Skin Diseases, Vesiculobullous; Sulfonamides; Transfection | 2012 |
Prostanoid receptors involved in regulation of the beating rate of neonatal rat cardiomyocytes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Cloprostenol; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Hydantoins; Iloprost; Latanoprost; Myocytes, Cardiac; Prostaglandin D2; Prostaglandins F, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane | 2012 |
Prostaglandin D2 inhibits collagen secretion from lung fibroblasts by activating the DP receptor.
Topics: Cells, Cultured; Collagen; Cyclic AMP; Fibroblasts; Humans; Hydantoins; Lung; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Transforming Growth Factor beta | 2013 |
Prostaglandin D2 receptor D-type prostanoid receptor 2 mediates eosinophil trafficking into the esophagus.
Topics: Animals; Carbazoles; Cell Movement; Eosinophil Major Basic Protein; Eosinophilic Esophagitis; Eosinophils; Epithelium; Esophagus; Guinea Pigs; Hydantoins; Male; Mast Cells; Ovalbumin; Prostaglandin Antagonists; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Sulfonamides | 2014 |
A novel indole compound, AWT-489, inhibits prostaglandin D2-induced CD55 expression by acting on DP prostanoid receptors as an antagonist in LS174T human colon cancer cells.
Topics: Carcinogenesis; CD55 Antigens; Cell Line, Tumor; Colonic Neoplasms; Cyclic AMP; Dinoprostone; Drug Design; Gene Expression Regulation, Neoplastic; Humans; Hydantoins; Indoles; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger | 2014 |
PGD2 DP1 receptor stimulation following stroke ameliorates cerebral blood flow and outcomes.
Topics: Animals; Brain; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Hydantoins; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Receptors, Immunologic; Receptors, Prostaglandin; Recovery of Function; Stroke | 2014 |
Exacerbation of Aging-Associated and Instability-Induced Murine Osteoarthritis With Deletion of D Prostanoid Receptor 1, a Prostaglandin D
Topics: ADAMTS5 Protein; Animals; Arthritis, Experimental; Cartilage; Disease Progression; Hydantoins; Interleukin-1alpha; Matrix Metalloproteinase 13; Mice; Mice, Inbred C57BL; Osteoarthritis, Knee; Proteoglycans; Receptors, Prostaglandin | 2017 |
Therapeutic potential of D prostanoid receptor 1 signal enhancement in a murine model of food allergy.
Topics: Animals; Disease Models, Animal; Female; Food Hypersensitivity; Hydantoins; Intestines; Mast Cells; Mice, Inbred BALB C; Receptors, Prostaglandin | 2019 |