Page last updated: 2024-09-03

bw 245c and dinoprostone

bw 245c has been researched along with dinoprostone in 17 studies

Compound Research Comparison

Studies
(bw 245c)
Trials
(bw 245c)
Recent Studies (post-2010)
(bw 245c)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
9631029,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomybw 245c (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's6 (35.29)18.2507
2000's7 (41.18)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abramovitz, M; Boie, Y; Metters, KM; Sawyer, N; Slipetz, DM1
Hirata, M; Kiriyama, M; Kobayashi, T; Narumiya, S; Sugimoto, Y; Ushikubi, F1
Abramovitz, M; Ford-Hutchinson, AW; Metters, KM; Wright, DH1
Ivanyi, J; Kay, JE; Kingston, AE1
Andersen, NH; Hanson, SR; Harker, LA; Tynan, SS; Wills, MT1
Lawrence, RA; Woodward, DF1
Leff, P; Lydford, SJ; McKechnie, KC1
Eguchi, N; Hayaishi, O; Ito, S; Kanaoka, Y; Minami, T; Nagata, A; Shirafuji, N; Tanaka, T; Urade, Y; Yoshida, N1
Hu, DN; McCormick, SA; Woodward, DF1
Cao, J; Kitazawa, T; Shayibuzhati, M; Tajima, T; Taneike, T1
Heinemann, A; Holzer, P; Peskar, BA; Shahbazian, A1
DeMasi, GM; Hardwick, JC; Jelson, GS; Sager, KL1
Sharif, NA; Xu, SX1
Jones, RL; Kan, KK; Ngan, MP; Rudd, JA1
de Brum-Fernandes, AJ; Gallant, MA; Miousse, MC; Parent, JL; Samadfam, R1
Devillier, P; Grassin-Delyle, S; Mechiche, H; Nazeyrollas, P; Robinet, A1
Arai, T; Awata, A; Fujino, H; Murayama, T; Okura, I; Oyama, S; Regan, JW; Yamazaki, R1

Other Studies

17 other study(ies) available for bw 245c and dinoprostone

ArticleYear
Molecular cloning and characterization of the human prostanoid DP receptor.
    The Journal of biological chemistry, 1995, Aug-11, Volume: 270, Issue:32

    Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Calcium; Cells, Cultured; Cloning, Molecular; Cyclic AMP; Humans; Molecular Sequence Data; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin

1995
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
    British journal of pharmacology, 1997, Volume: 122, Issue:2

    Topics: Animals; CHO Cells; Cricetinae; Ligands; Mice; Prostaglandins; Receptors, Prostaglandin; Transfection

1997
Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist.
    British journal of pharmacology, 1998, Volume: 123, Issue:7

    Topics: Adenine Nucleotides; Benzoates; Binding, Competitive; Cell Line; Cyclic AMP; Dinoprostone; Guanine Nucleotides; Humans; Kinetics; Receptors, Immunologic; Receptors, Prostaglandin; Recombinant Proteins; Thiazoles; Thiazolidines; Tritium

1998
The effects of prostaglandin E and I analogues on lymphocyte stimulation.
    International journal of immunopharmacology, 1985, Volume: 7, Issue:1

    Topics: Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Leucine; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Prostaglandins E; Prostaglandins E, Synthetic; Protein Biosynthesis

1985
On the multiplicity of platelet prostaglandin receptors. II. The use of N-0164 for distinguishing the loci of action for PGI2, PGD2, PGE2 and hydantoin analogs.
    Prostaglandins, 1984, Volume: 27, Issue:5

    Topics: Blood Platelets; Dinoprostone; Epoprostenol; Humans; Hydantoins; Organophosphonates; Organophosphorus Compounds; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Receptors, Cell Surface; Receptors, Prostaglandin; Structure-Activity Relationship

1984
Identification of a single (FP) receptor associated with prostanoid-induced Ca2+ signals in Swiss 3T3 cells.
    Biochemical pharmacology, 1994, Apr-29, Volume: 47, Issue:9

    Topics: 3T3 Cells; Animals; Binding, Competitive; Calcium; Dinoprostone; Hydantoins; Mice; Prostaglandin D2; Prostaglandins F; Prostaglandins F, Synthetic; Receptors, Prostaglandin; Second Messenger Systems

1994
Interaction of BW A868C, a prostanoid DP-receptor antagonist, with two receptor subtypes in the rabbit isolated saphenous vein.
    Prostaglandins, 1996, Volume: 52, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Biphenyl Compounds; Dinoprostone; Dose-Response Relationship, Drug; Hydantoins; Male; Potassium Chloride; Prostaglandin D2; Rabbits; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Saphenous Vein

1996
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jan-19, Volume: 96, Issue:2

    Topics: Anesthesia; Animals; Bicuculline; Central Nervous System; Dinoprost; Dinoprostone; GABA Antagonists; Gene Targeting; Hydantoins; Hyperalgesia; Immunohistochemistry; Intramolecular Oxidoreductases; Lipocalins; Mice; Mice, Knockout; Molecular Sequence Data; Pain; Prostaglandin D2; Receptors, Prostaglandin

1999
A functional study on prostanoid receptors involved in cultured human iridal melanocyte stimulation.
    Experimental eye research, 2001, Volume: 73, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Cell Count; Cells, Cultured; Cyclic AMP; Dinoprostone; Epoprostenol; Fibroblast Growth Factor 2; Humans; Hydantoins; Iris; Melanins; Melanocytes; Prostaglandin Antagonists; Prostanoic Acids; Receptors, Prostaglandin

2001
In vitro pharmacological characterization of the prostanoid receptor population in the non-pregnant porcine myometrium.
    European journal of pharmacology, 2002, May-03, Volume: 442, Issue:1-2

    Topics: Animals; Cloprostenol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Female; Hydantoins; Iloprost; In Vitro Techniques; Muscle Contraction; Myometrium; Prostaglandin D2; Receptors, Prostaglandin; Swine

2002
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dinoprostone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Guinea Pigs; Hydantoins; Hydrazines; Iloprost; In Vitro Techniques; Intestine, Small; Leukotriene Antagonists; Leukotriene D4; Male; Oxazepines; Peristalsis; Prostaglandin D2; Prostaglandins A; Receptors, Leukotriene; Receptors, Prostaglandin; Xanthenes; Xanthones; Yohimbine

2002
Modulation of guinea pig intrinsic cardiac neurons by prostaglandins.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 285, Issue:3

    Topics: Animals; Dinoprostone; Female; Ganglia, Parasympathetic; Guinea Pigs; Heart; Hydantoins; Male; Mast Cells; Membrane Potentials; Phospholipases A; Phospholipases A2; Potassium Channel Blockers; Prostaglandin D2; Receptors, Prostaglandin; Xanthenes; Xanthones

2003
Pharmacological characterization and identification of EP3 prostanoid receptor binding sites in hamster uterus homogenates.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:2

    Topics: Animals; Binding Sites; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cloprostenol; Cricetinae; Dinoprost; Dinoprostone; Enprostil; Epoprostenol; Fatty Acids, Unsaturated; Female; Hydantoins; Hydrazines; Iloprost; Latanoprost; Misoprostol; Prostaglandins; Prostaglandins E, Synthetic; Prostaglandins F, Synthetic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Tritium; Uterus

2004
Excitatory action of prostanoids on the ferret isolated vagus nerve preparation.
    European journal of pharmacology, 2004, Apr-26, Volume: 491, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Biguanides; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Electrophysiology; Epoprostenol; Ferrets; Hydantoins; Iloprost; In Vitro Techniques; Male; Prostaglandins; Prostaglandins F, Synthetic; Serotonin; Vagus Nerve

2004
Implication of prostaglandin receptors in the accumulation of osteoprotegerin in human osteoblast cultures.
    The Journal of rheumatology, 2006, Volume: 33, Issue:6

    Topics: Cell Line, Transformed; Cell Line, Tumor; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Gene Expression; Glycoproteins; Humans; Hydantoins; Osteoblasts; Osteoprotegerin; Prostaglandin-Endoperoxide Synthases; Prostaglandins F, Synthetic; Receptors, Cytoplasmic and Nuclear; Receptors, Prostaglandin; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2006
Prostanoid receptors involved in regulation of the beating rate of neonatal rat cardiomyocytes.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Cloprostenol; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Hydantoins; Iloprost; Latanoprost; Myocytes, Cardiac; Prostaglandin D2; Prostaglandins F, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane

2012
A novel indole compound, AWT-489, inhibits prostaglandin D2-induced CD55 expression by acting on DP prostanoid receptors as an antagonist in LS174T human colon cancer cells.
    Archives of biochemistry and biophysics, 2014, Jan-01, Volume: 541

    Topics: Carcinogenesis; CD55 Antigens; Cell Line, Tumor; Colonic Neoplasms; Cyclic AMP; Dinoprostone; Drug Design; Gene Expression Regulation, Neoplastic; Humans; Hydantoins; Indoles; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger

2014