Page last updated: 2024-09-03

bw 245c and dinoprost

bw 245c has been researched along with dinoprost in 13 studies

Compound Research Comparison

Studies
(bw 245c)
Trials
(bw 245c)
Recent Studies (post-2010)
(bw 245c)
Studies
(dinoprost)
Trials
(dinoprost)
Recent Studies (post-2010) (dinoprost)
9631011,5549401,936

Protein Interaction Comparison

ProteinTaxonomybw 245c (IC50)dinoprost (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.0025
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.0713
Prostaglandin G/H synthase 1Homo sapiens (human)0.14
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.3
Prostaglandin G/H synthase 2Homo sapiens (human)0.14
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)4.2
Prostaglandin F2-alpha receptorBos taurus (cattle)0.14
Prostaglandin F2-alpha receptorHomo sapiens (human)0.0139
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.216
Prostaglandin D2 receptorHomo sapiens (human)4.5
Solute carrier organic anion transporter family member 2B1Rattus norvegicus (Norway rat)0.287

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's8 (61.54)18.2507
2000's4 (30.77)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirata, M; Kiriyama, M; Kobayashi, T; Narumiya, S; Sugimoto, Y; Ushikubi, F1
Abramovitz, M; Ford-Hutchinson, AW; Metters, KM; Wright, DH1
Fairbairn, CE; Goodrum, DD; Krauss, AH; Ralston, TL; Williams, LS; Woodward, DF1
Church, MK; Featherstone, RL; Holgate, ST; Robinson, C1
Hawley, SB; Nieves, AL; Protzman, CE; Ralston, TR; Spada, CS; Williams, LS; Woodward, DF1
Keery, RJ; Lumley, P1
Crankshaw, D; Fernandes, B1
Eguchi, N; Hayaishi, O; Ito, S; Kanaoka, Y; Minami, T; Nagata, A; Shirafuji, N; Tanaka, T; Urade, Y; Yoshida, N1
Chan, CL; Lau, HY1
Chan, CL; Jones, RL; Lau, HY1
Cao, J; Kitazawa, T; Shayibuzhati, M; Tajima, T; Taneike, T1
Sharif, NA; Xu, SX1
Jones, RL; Kan, KK; Ngan, MP; Rudd, JA1

Other Studies

13 other study(ies) available for bw 245c and dinoprost

ArticleYear
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
    British journal of pharmacology, 1997, Volume: 122, Issue:2

    Topics: Animals; CHO Cells; Cricetinae; Ligands; Mice; Prostaglandins; Receptors, Prostaglandin; Transfection

1997
Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist.
    British journal of pharmacology, 1998, Volume: 123, Issue:7

    Topics: Adenine Nucleotides; Benzoates; Binding, Competitive; Cell Line; Cyclic AMP; Dinoprostone; Guanine Nucleotides; Humans; Kinetics; Receptors, Immunologic; Receptors, Prostaglandin; Recombinant Proteins; Thiazoles; Thiazolidines; Tritium

1998
Ca2+ transients evoked by prostanoids in Swiss 3T3 cells suggest an FP-receptor mediated response.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Dinoprost; Dose-Response Relationship, Drug; Fibroblasts; Hydantoins; Mice; Phenylacetates; Platelet-Derived Growth Factor; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins F, Synthetic; Receptors, Prostaglandin; Sulfonamides

1991
Evidence for thromboxane receptor mediated contraction of guinea-pig and human airways in vitro by prostaglandin (PG) D2, 9 alpha,11 beta-PGF2 and PGF2 alpha.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:5

    Topics: Animals; Biphenyl Compounds; Bronchi; Dinoprost; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Humans; Hydantoins; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin D2; Prostaglandins, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxanes; Trachea

1990
Studies on the ocular pharmacology of prostaglandin D2.
    Investigative ophthalmology & visual science, 1990, Volume: 31, Issue:1

    Topics: Animals; Aqueous Humor; Capillary Permeability; Chemotaxis, Leukocyte; Conjunctiva; Dinoprost; Eosinophils; Evans Blue; Eye; Female; Guinea Pigs; Hydantoins; Inflammation; Intraocular Pressure; Male; Prostaglandin D2; Rabbits

1990
AH6809, a prostaglandin DP-receptor blocking drug on human platelets.
    British journal of pharmacology, 1988, Volume: 94, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Dinoprost; Epoprostenol; Humans; Hydantoins; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Receptors, Immunologic; Receptors, Prostaglandin; Xanthenes; Xanthones

1988
Functional characterization of the prostanoid DP receptor in human myometrium.
    European journal of pharmacology, 1995, Sep-05, Volume: 283, Issue:1-3

    Topics: Adult; Dinoprost; Dose-Response Relationship, Drug; Female; Humans; Hydantoins; Hysterectomy; Middle Aged; Muscle Contraction; Muscle, Smooth; Myometrium; Prostaglandin D2; Prostanoic Acids; Receptors, Prostaglandin

1995
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jan-19, Volume: 96, Issue:2

    Topics: Anesthesia; Animals; Bicuculline; Central Nervous System; Dinoprost; Dinoprostone; GABA Antagonists; Gene Targeting; Hydantoins; Hyperalgesia; Immunohistochemistry; Intramolecular Oxidoreductases; Lipocalins; Mice; Mice, Knockout; Molecular Sequence Data; Pain; Prostaglandin D2; Receptors, Prostaglandin

1999
Prostanoid DP receptor activation inhibits anti-IgE induced histamine release from rat peritoneal mast cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1999, Volume: 48 Suppl 1

    Topics: Animals; Antibodies; Dinoprost; Histamine Release; Hydantoins; Immunoglobulin E; Male; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin

1999
Characterization of prostanoid receptors mediating inhibition of histamine release from anti-IgE-activated rat peritoneal mast cells.
    British journal of pharmacology, 2000, Volume: 129, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Algorithms; Animals; Dinoprost; Histamine Release; Hydantoins; Hypersensitivity, Immediate; Male; Mast Cells; Peritoneal Cavity; Prostaglandin Antagonists; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin

2000
In vitro pharmacological characterization of the prostanoid receptor population in the non-pregnant porcine myometrium.
    European journal of pharmacology, 2002, May-03, Volume: 442, Issue:1-2

    Topics: Animals; Cloprostenol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Female; Hydantoins; Iloprost; In Vitro Techniques; Muscle Contraction; Myometrium; Prostaglandin D2; Receptors, Prostaglandin; Swine

2002
Pharmacological characterization and identification of EP3 prostanoid receptor binding sites in hamster uterus homogenates.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:2

    Topics: Animals; Binding Sites; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cloprostenol; Cricetinae; Dinoprost; Dinoprostone; Enprostil; Epoprostenol; Fatty Acids, Unsaturated; Female; Hydantoins; Hydrazines; Iloprost; Latanoprost; Misoprostol; Prostaglandins; Prostaglandins E, Synthetic; Prostaglandins F, Synthetic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Tritium; Uterus

2004
Excitatory action of prostanoids on the ferret isolated vagus nerve preparation.
    European journal of pharmacology, 2004, Apr-26, Volume: 491, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Biguanides; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Electrophysiology; Epoprostenol; Ferrets; Hydantoins; Iloprost; In Vitro Techniques; Male; Prostaglandins; Prostaglandins F, Synthetic; Serotonin; Vagus Nerve

2004